Search results for: Jacobo Bielak

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Bielak</title> <meta name="description" content="Search results for: Jacobo Bielak"> <meta name="keywords" content="Jacobo Bielak"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Jacobo Bielak"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 4</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Jacobo Bielak</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Soil-Structure Interaction in Stiffness and Strength Degrading Systems</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Enrique%20Bazan-Zurita">Enrique Bazan-Zurita</a>, <a href="https://publications.waset.org/abstracts/search?q=Sittipong%20Jarernprasert"> Sittipong Jarernprasert</a>, <a href="https://publications.waset.org/abstracts/search?q=Jacobo%20Bielak"> Jacobo Bielak</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We study the effects of soil-structure interaction (SSI) on the inelastic seismic response of a single-degree-of-freedom system whose hysteretic behaviour exhibits stiffness and/or strength degrading characteristics. Two sets of accelerograms are used as seismic input: the first comprising 87 record from stiff to medium stiff sites in California, and the second comprising 66 records from the soft lakebed of Mexico City. This study focuses in three seismic response parameters: ductility demand, inter-story drift, and total lateral displacement. The results allow quantitative estimates of changes in such parameters in an SSI system in comparison with those corresponding to the associated fixed-base system. We found that degrading features affect significantly both the response of fixed-base structures and the impact of soil-structure interaction. We propose a procedure to incorporate the results of this and similar studies in seismic design regulations for SSI system with anticipated nonlinear degrading behaviour. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=inelastic" title="inelastic">inelastic</a>, <a href="https://publications.waset.org/abstracts/search?q=seismic" title=" seismic"> seismic</a>, <a href="https://publications.waset.org/abstracts/search?q=building" title=" building"> building</a>, <a href="https://publications.waset.org/abstracts/search?q=foundation" title=" foundation"> foundation</a>, <a href="https://publications.waset.org/abstracts/search?q=interaction" title=" interaction"> interaction</a> </p> <a href="https://publications.waset.org/abstracts/7045/soil-structure-interaction-in-stiffness-and-strength-degrading-systems" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7045.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">286</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Viscoelastic Characterization of Bovine Trabecular Bone Samples</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20Ramirez%20D.%20Edgar">I. Ramirez D. Edgar</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Angeles%20H.%20Jos%C3%A9"> J. Angeles H. Jos茅</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruiz%20C.%20Osvaldo"> Ruiz C. Osvaldo</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Jacobo%20A.%20Victor"> H. Jacobo A. Victor</a>, <a href="https://publications.waset.org/abstracts/search?q=Ortiz%20P.%20Armando"> Ortiz P. Armando</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Knowledge of bone mechanical properties is important for bone substitutes design and fabrication, and more efficient prostheses development. The aim of this study is to characterize the viscoelastic behavior of bone specimens, through stress relaxation and fatigue tests performed to trabecular bone samples from bovine femoral heads. Relaxation tests consisted on preloading the samples at five different magnitudes and evaluate them for 1020 seconds, adjusting the results to a KWW mathematical model. Fatigue tests consisted of 700 load cycles and analyze their status at the end of the tests. As a conclusion we have that between relaxation stress and each preload there is linear relation and for samples with initial Young麓s modulus greater than 1.5 GPa showed no effects due fatigue test loading cycles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20viscoelasticity" title="bone viscoelasticity">bone viscoelasticity</a>, <a href="https://publications.waset.org/abstracts/search?q=fatigue%20test" title=" fatigue test"> fatigue test</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20relaxation%20test" title=" stress relaxation test"> stress relaxation test</a>, <a href="https://publications.waset.org/abstracts/search?q=trabecular%20bone%20properties" title=" trabecular bone properties"> trabecular bone properties</a> </p> <a href="https://publications.waset.org/abstracts/21146/viscoelastic-characterization-of-bovine-trabecular-bone-samples" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21146.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">489</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Evaluation of Toxic Metals in Water Hyacinth (Eichhornia crassipes) from Valsequillo Reservoir, Puebla, Central Mexico</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jacobo%20Tabla">Jacobo Tabla</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20F.%20Rodriguez-Espinosa"> P. F. Rodriguez-Espinosa</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20E.%20Perez-Lopez"> M. E. Perez-Lopez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Valsequillo reservoir located in Puebla City, Central Mexico receives water from the Atoyac River (Northwest) and from Alseseca River in the north. It has been the receptacle of municipal and industrial wastes for the past few decades affecting the water quality lethally. As a result, there is an outburst of water hyacinths (Eichhornia crassipes) in the reservoir occupying around 50 % of the total area. Therefore, the aim of the present work was to assess the concentration levels of toxic metals (Co, Zn, Ni, Cu and As) in the water hyacinths and the ambient waters during the dry season. Fourteen water samples and three water hyacinth samples were procured from the Valsequillo reservoir. The collected samples of water hyacinth (roots, rhizome, stems and leaves) were analyzed using an Inductively coupled plasma mass spectrometry (ICP-MS) Ultramass 700 (Varian Inc.) to determine the metal levels. Results showed that water hyacinth presented an exhaustion in metal capture from the inlet to outlet of the reservoir. The maximum bioaccumulation factors (BF) of Co, Zn, Ni, Cu and As were 5000, 47474, 4929, 17090 and 74000 respectively. On the other hand, the maximum Translocation Factor (TF) of 0.85 was observed in Zn, whilst Co presented the minimum TF of 0.059. Thus, the results presented the fact that water hyacinth in Valsequillo reservoir proves to be an important environmental utility for efficiently accumulating and translocating heavy metals from the ambient waters to its organelles (stems and leaves). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bioaccumulation%20factor" title="bioaccumulation factor">bioaccumulation factor</a>, <a href="https://publications.waset.org/abstracts/search?q=toxic%20metals" title=" toxic metals"> toxic metals</a>, <a href="https://publications.waset.org/abstracts/search?q=translocation%20factor" title=" translocation factor"> translocation factor</a>, <a href="https://publications.waset.org/abstracts/search?q=water%20hyacinth" title=" water hyacinth"> water hyacinth</a> </p> <a href="https://publications.waset.org/abstracts/67434/evaluation-of-toxic-metals-in-water-hyacinth-eichhornia-crassipes-from-valsequillo-reservoir-puebla-central-mexico" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/67434.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">255</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Design of DNA Origami Structures Using LAMP Products as a Combined System for the Detection of Extended Spectrum B-Lactamases</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kalaumari%20Mayoral-Pe%C3%B1a">Kalaumari Mayoral-Pe帽a</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20I.%20Montejano-Montelongo"> Ana I. Montejano-Montelongo</a>, <a href="https://publications.waset.org/abstracts/search?q=Josu%C3%A9%20Reyes-Mu%C3%B1oz"> Josu茅 Reyes-Mu帽oz</a>, <a href="https://publications.waset.org/abstracts/search?q=Gonzalo%20A.%20Ortiz-Mancilla"> Gonzalo A. Ortiz-Mancilla</a>, <a href="https://publications.waset.org/abstracts/search?q=Mayrin%20Rodr%C3%ADguez-Cruz"> Mayrin Rodr铆guez-Cruz</a>, <a href="https://publications.waset.org/abstracts/search?q=V%C3%ADctor%20Hern%C3%A1ndez-Villalobos"> V铆ctor Hern谩ndez-Villalobos</a>, <a href="https://publications.waset.org/abstracts/search?q=Jes%C3%BAs%20A.%20Guzm%C3%A1n-L%C3%B3pez"> Jes煤s A. Guzm谩n-L贸pez</a>, <a href="https://publications.waset.org/abstracts/search?q=Santiago%20Garc%C3%ADa-Jacobo"> Santiago Garc铆a-Jacobo</a>, <a href="https://publications.waset.org/abstracts/search?q=Iv%C3%A1n%20Licona-V%C3%A1zquez"> Iv谩n Licona-V谩zquez</a>, <a href="https://publications.waset.org/abstracts/search?q=Grisel%20Fierros-Romero"> Grisel Fierros-Romero</a>, <a href="https://publications.waset.org/abstracts/search?q=Rosario%20Flores-Vallejo"> Rosario Flores-Vallejo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The group B-lactamic antibiotics include some of the most frequently used small drug molecules against bacterial infections. Nevertheless, an alarming decrease in their efficacy has been reported due to the emergence of antibiotic-resistant bacteria. Infections caused by bacteria expressing extended Spectrum B-lactamases (ESBLs) are difficult to treat and account for higher morbidity and mortality rates, delayed recovery, and high economic burden. According to the Global Report on Antimicrobial Resistance Surveillance, it is estimated that mortality due to resistant bacteria will ascend to 10 million cases per year worldwide. These facts highlight the importance of developing low-cost and readily accessible detection methods of drug-resistant ESBLs bacteria to prevent their spread and promote accurate and fast diagnosis. Bacterial detection is commonly done using molecular diagnostic techniques, where PCR stands out for its high performance. However, this technique requires specialized equipment not available everywhere, is time-consuming, and has a high cost. Loop-Mediated Isothermal Amplification (LAMP) is an alternative technique that works at a constant temperature, significantly decreasing the equipment cost. It yields double-stranded DNA of several lengths with repetitions of the target DNA sequence as a product. Although positive and negative results from LAMP can be discriminated by colorimetry, fluorescence, and turbidity, there is still a large room for improvement in the point-of-care implementation. DNA origami is a technique that allows the formation of 3D nanometric structures by folding a large single-stranded DNA (scaffold) into a determined shape with the help of short DNA sequences (staples), which hybridize with the scaffold. This research aimed to generate DNA origami structures using LAMP products as scaffolds to improve the sensitivity to detect ESBLs in point-of-care diagnosis. For this study, the coding sequence of the CTM-X-15 ESBL of E. coli was used to generate the LAMP products. The set of LAMP primers were designed using PrimerExplorerV5. As a result, a target sequence of 200 nucleotides from CTM-X-15 ESBL was obtained. Afterward, eight different DNA origami structures were designed using the target sequence in the SDCadnano and analyzed with CanDo to evaluate the stability of the 3D structures. The designs were constructed minimizing the total number of staples to reduce costs and complexity for point-of-care applications. After analyzing the DNA origami designs, two structures were selected. The first one was a zig-zag flat structure, while the second one was a wall-like shape. Given the sequence repetitions in the scaffold sequence, both were able to be assembled with only 6 different staples each one, ranging between 18 to 80 nucleotides. Simulations of both structures were performed using scaffolds of different sizes yielding stable structures in all the cases. The generation of the LAMP products were tested by colorimetry and electrophoresis. The formation of the DNA structures was analyzed using electrophoresis and colorimetry. The modeling of novel detection methods through bioinformatics tools allows reliable control and prediction of results. To our knowledge, this is the first study that uses LAMP products and DNA-origami in combination to delect ESBL-producing bacterial strains, which represent a promising methodology for diagnosis in the point-of-care. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=beta-lactamases" title="beta-lactamases">beta-lactamases</a>, <a href="https://publications.waset.org/abstracts/search?q=antibiotic%20resistance" title=" antibiotic resistance"> antibiotic resistance</a>, <a href="https://publications.waset.org/abstracts/search?q=DNA%20origami" title=" DNA origami"> DNA origami</a>, <a href="https://publications.waset.org/abstracts/search?q=isothermal%20amplification" title=" isothermal amplification"> isothermal amplification</a>, <a href="https://publications.waset.org/abstracts/search?q=LAMP%20technique" title=" LAMP technique"> LAMP technique</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20diagnosis" title=" molecular diagnosis"> molecular diagnosis</a> </p> <a href="https://publications.waset.org/abstracts/142416/design-of-dna-origami-structures-using-lamp-products-as-a-combined-system-for-the-detection-of-extended-spectrum-b-lactamases" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/142416.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">222</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" 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Search results for: Jacobo Bielak