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Oligodendrócito – Wikipédia, a enciclopédia livre
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<ul id="toc-Referências-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Bibliografia" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Bibliografia"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Bibliografia</span> </div> </a> <ul id="toc-Bibliografia-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Ligações_externas" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Ligações_externas"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>Ligações externas</span> </div> </a> <ul id="toc-Ligações_externas-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Conteúdo" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Alternar o índice" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Alternar o índice</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Oligodendrócito</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Ir para um artigo noutra língua. Disponível em 30 línguas" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-30" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">30 línguas</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AE%D9%84%D9%8A%D8%A9_%D8%AF%D8%A8%D9%82%D9%8A%D8%A9_%D9%82%D9%84%D9%8A%D9%84%D8%A9_%D8%A7%D9%84%D8%AA%D8%BA%D8%B5%D9%86" title="خلية دبقية قليلة التغصن — árabe" lang="ar" hreflang="ar" data-title="خلية دبقية قليلة التغصن" data-language-autonym="العربية" data-language-local-name="árabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%9E%D0%BB%D0%B8%D0%B3%D0%BE%D0%B4%D0%B5%D0%BD%D0%B4%D1%80%D0%BE%D1%86%D0%B8%D1%82" title="Олигодендроцит — búlgaro" lang="bg" hreflang="bg" data-title="Олигодендроцит" data-language-autonym="Български" data-language-local-name="búlgaro" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Oligodendrocit" title="Oligodendrocit — bósnio" lang="bs" hreflang="bs" data-title="Oligodendrocit" data-language-autonym="Bosanski" data-language-local-name="bósnio" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Oligodendrocyt" title="Oligodendrocyt — checo" lang="cs" hreflang="cs" data-title="Oligodendrocyt" data-language-autonym="Čeština" data-language-local-name="checo" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Oligodendrocyt" title="Oligodendrocyt — dinamarquês" lang="da" hreflang="da" data-title="Oligodendrocyt" data-language-autonym="Dansk" data-language-local-name="dinamarquês" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Oligodendrozyt" title="Oligodendrozyt — alemão" lang="de" hreflang="de" data-title="Oligodendrozyt" data-language-autonym="Deutsch" data-language-local-name="alemão" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Oligodendrocyte" title="Oligodendrocyte — inglês" lang="en" hreflang="en" data-title="Oligodendrocyte" data-language-autonym="English" data-language-local-name="inglês" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Oligodendrocito" title="Oligodendrocito — espanhol" lang="es" hreflang="es" data-title="Oligodendrocito" data-language-autonym="Español" data-language-local-name="espanhol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A7%D9%84%DB%8C%DA%AF%D9%88%D8%AF%D9%86%D8%AF%D8%B1%D9%88%D8%B3%DB%8C%D8%AA" title="الیگودندروسیت — persa" lang="fa" hreflang="fa" data-title="الیگودندروسیت" data-language-autonym="فارسی" data-language-local-name="persa" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Oligodendrocyte" title="Oligodendrocyte — francês" lang="fr" hreflang="fr" data-title="Oligodendrocyte" data-language-autonym="Français" data-language-local-name="francês" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Oligodendrocito" title="Oligodendrocito — galego" lang="gl" hreflang="gl" data-title="Oligodendrocito" data-language-autonym="Galego" data-language-local-name="galego" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%90%D7%95%D7%9C%D7%99%D7%92%D7%95%D7%93%D7%A0%D7%93%D7%A8%D7%95%D7%A6%D7%99%D7%98%D7%99%D7%9D" title="אוליגודנדרוציטים — hebraico" lang="he" hreflang="he" data-title="אוליגודנדרוציטים" data-language-autonym="עברית" data-language-local-name="hebraico" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%95%D5%AC%D5%AB%D5%A3%D5%B8%D5%A4%D5%A5%D5%B6%D5%A4%D6%80%D5%B8%D6%81%D5%AB%D5%BF" title="Օլիգոդենդրոցիտ — arménio" lang="hy" hreflang="hy" data-title="Օլիգոդենդրոցիտ" data-language-autonym="Հայերեն" data-language-local-name="arménio" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Oligodendrosit" title="Oligodendrosit — indonésio" lang="id" hreflang="id" data-title="Oligodendrosit" data-language-autonym="Bahasa Indonesia" data-language-local-name="indonésio" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Oligodendrocita" title="Oligodendrocita — italiano" lang="it" hreflang="it" data-title="Oligodendrocita" data-language-autonym="Italiano" data-language-local-name="italiano" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E5%B8%8C%E7%AA%81%E8%B5%B7%E8%86%A0%E7%B4%B0%E8%83%9E" title="希突起膠細胞 — japonês" lang="ja" hreflang="ja" data-title="希突起膠細胞" data-language-autonym="日本語" data-language-local-name="japonês" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%ED%9D%AC%EC%86%8C%EB%8F%8C%EA%B8%B0%EC%95%84%EA%B5%90%EC%84%B8%ED%8F%AC" title="희소돌기아교세포 — coreano" lang="ko" hreflang="ko" data-title="희소돌기아교세포" data-language-autonym="한국어" data-language-local-name="coreano" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/Oligodendrocytus" title="Oligodendrocytus — latim" lang="la" hreflang="la" data-title="Oligodendrocytus" data-language-autonym="Latina" data-language-local-name="latim" class="interlanguage-link-target"><span>Latina</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Oligodendrocyt" title="Oligodendrocyt — neerlandês" lang="nl" hreflang="nl" data-title="Oligodendrocyt" data-language-autonym="Nederlands" data-language-local-name="neerlandês" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-nn mw-list-item"><a href="https://nn.wikipedia.org/wiki/Oligodendrocytt" title="Oligodendrocytt — norueguês nynorsk" lang="nn" hreflang="nn" data-title="Oligodendrocytt" data-language-autonym="Norsk nynorsk" data-language-local-name="norueguês nynorsk" class="interlanguage-link-target"><span>Norsk nynorsk</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Oligodendrocyt" title="Oligodendrocyt — polaco" lang="pl" hreflang="pl" data-title="Oligodendrocyt" data-language-autonym="Polski" data-language-local-name="polaco" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Oligodendroglie" title="Oligodendroglie — romeno" lang="ro" hreflang="ro" data-title="Oligodendroglie" data-language-autonym="Română" data-language-local-name="romeno" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9E%D0%BB%D0%B8%D0%B3%D0%BE%D0%B4%D0%B5%D0%BD%D0%B4%D1%80%D0%BE%D1%86%D0%B8%D1%82%D1%8B" title="Олигодендроциты — russo" lang="ru" hreflang="ru" data-title="Олигодендроциты" data-language-autonym="Русский" data-language-local-name="russo" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Oligodendroglia" title="Oligodendroglia — eslovaco" lang="sk" hreflang="sk" data-title="Oligodendroglia" data-language-autonym="Slovenčina" data-language-local-name="eslovaco" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Oligodendrocit" title="Oligodendrocit — esloveno" lang="sl" hreflang="sl" data-title="Oligodendrocit" data-language-autonym="Slovenščina" data-language-local-name="esloveno" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%9E%D0%BB%D0%B8%D0%B3%D0%BE%D0%B4%D0%B5%D0%BD%D0%B4%D1%80%D0%BE%D1%86%D0%B8%D1%82%D0%B8" title="Олигодендроцити — sérvio" lang="sr" hreflang="sr" data-title="Олигодендроцити" data-language-autonym="Српски / srpski" data-language-local-name="sérvio" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Oligodendrocyt" title="Oligodendrocyt — sueco" lang="sv" hreflang="sv" data-title="Oligodendrocyt" data-language-autonym="Svenska" data-language-local-name="sueco" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B9%82%E0%B8%AD%E0%B8%A5%E0%B8%B4%E0%B9%82%E0%B8%81%E0%B9%80%E0%B8%94%E0%B8%99%E0%B9%82%E0%B8%94%E0%B8%A3%E0%B9%84%E0%B8%8B%E0%B8%95%E0%B9%8C" title="โอลิโกเดนโดรไซต์ — tailandês" lang="th" hreflang="th" data-title="โอลิโกเดนโดรไซต์" data-language-autonym="ไทย" data-language-local-name="tailandês" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9E%D0%BB%D1%96%D0%B3%D0%BE%D0%B4%D0%B5%D0%BD%D0%B4%D1%80%D0%BE%D1%86%D0%B8%D1%82" title="Олігодендроцит — ucraniano" 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livre.</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="pt" dir="ltr"><table class="infobox infobox_v2" cellpadding="3" border="0" style="width: 270px; font-size: 88%; line-height: 1.2em;"> <tbody><tr> <th colspan="2" class="topo padrao" style="text-align:center; font-size:large; background-color:lightblue; border-radius: 3px 3px 0 0;"><span class="">Oligodendrócito</span> </th></tr> <tr> <td colspan="2" style="text-align:center;"><div style="padding-bottom: 5px;"><figure class="mw-halign-center" typeof="mw:File"><a href="/wiki/Ficheiro:Oligodendrocytes.tif" class="mw-file-description" title="Oligodendrócito"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/Oligodendrocytes.tif/lossless-page1-200px-Oligodendrocytes.tif.png" decoding="async" width="200" height="199" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/de/Oligodendrocytes.tif/lossless-page1-300px-Oligodendrocytes.tif.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/de/Oligodendrocytes.tif/lossless-page1-400px-Oligodendrocytes.tif.png 2x" data-file-width="2248" data-file-height="2235" /></a><figcaption>Oligodendrócito</figcaption></figure></div> </td></tr> <tr> <td colspan="2" style="text-align:center;"><div style="padding-bottom: 5px;"><figure class="mw-halign-center" typeof="mw:File"><a href="/wiki/Ficheiro:Oligodendrocyte_illustration.png" class="mw-file-description" title="Oligodendrócito"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Oligodendrocyte_illustration.png/200px-Oligodendrocyte_illustration.png" decoding="async" width="200" height="159" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Oligodendrocyte_illustration.png/300px-Oligodendrocyte_illustration.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Oligodendrocyte_illustration.png/400px-Oligodendrocyte_illustration.png 2x" data-file-width="1146" data-file-height="913" /></a><figcaption>Oligodendrócito</figcaption></figure></div> </td></tr> <tr> <td scope="row" style="vertical-align: top; text-align: left; font-weight:bold; padding:4px 4px 4px 0;">Subclasse de </td> <td style="vertical-align: top; text-align: left; padding:4px 4px 4px 0;"><a href="/wiki/Neur%C3%B3glia" title="Neuróglia">neuróglia</a>, macroglia, set of macroglial cells </td></tr> <tr> <td scope="row" style="vertical-align: top; text-align: left; font-weight:bold; padding:4px 4px 4px 0;">Cell Ontology </td> <td style="vertical-align: top; text-align: left; padding:4px 4px 4px 0;"><a rel="nofollow" class="external text" href="http://purl.obolibrary.org/obo/CL_0000128">CL_0000128</a> </td></tr> <tr> <td scope="row" style="vertical-align: top; text-align: left; font-weight:bold; padding:4px 4px 4px 0;">MeSH </td> <td style="vertical-align: top; text-align: left; padding:4px 4px 4px 0;"><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=D009836">D009836</a> </td></tr> <tr> <td scope="row" style="vertical-align: top; text-align: left; font-weight:bold; padding:4px 4px 4px 0;">Foundational Model of Anatomy </td> <td style="vertical-align: top; text-align: left; padding:4px 4px 4px 0;"><a rel="nofollow" class="external text" href="http://purl.org/sig/ont/fma/fma54540,">83665 54540, 83665</a> </td></tr> <tr> <td colspan="2" style="text-align:center; padding:4px 0 4px 4px; background-color:lightblue"><div style="text-align: right;">[<a href="https://www.wikidata.org/wiki/Q916698" class="extiw" title="d:Q916698">edite no Wikidata</a>]</div> </td></tr> </tbody></table> <p><b>Oligodendrócitos</b> (do <a href="/wiki/L%C3%ADngua_grega" title="Língua grega">grego</a>, 'células com alguns ramos') são um tipo de <a href="/wiki/C%C3%A9lula_da_glia" class="mw-redirect" title="Célula da glia">célula da glia</a> cujas funções principais são fornecer suporte e isolamento para <a href="/wiki/Ax%C3%B4nio" class="mw-redirect" title="Axônio">axônios</a> no <a href="/wiki/Sistema_nervoso_central" title="Sistema nervoso central">sistema nervoso central</a> de alguns <a href="/wiki/Vertebrados" title="Vertebrados">vertebrados</a>, equivalente à função desempenhada pelas <a href="/wiki/C%C3%A9lulas_de_Schwann" class="mw-redirect" title="Células de Schwann">células de Schwann</a> no <a href="/wiki/Sistema_nervoso_perif%C3%A9rico" title="Sistema nervoso periférico">sistema nervoso periférico</a>. Os oligodendrócitos fazem isso criando a <a href="/wiki/Bainha_de_mielina" title="Bainha de mielina">bainha de mielina</a>.<sup id="cite_ref-CarlsonPhysiology_1-0" class="reference"><a href="#cite_note-CarlsonPhysiology-1"><span>[</span>1<span>]</span></a></sup> Um único oligodendrócito pode estender seus processos para 50 axônios,<sup id="cite_ref-Baumann2011_2-0" class="reference"><a href="#cite_note-Baumann2011-2"><span>[</span>2<span>]</span></a></sup> envolvendo aproximadamente 1 μm de bainha de mielina em torno de cada axônio; As células de Schwann, por outro lado, podem envolver apenas um axônio. Cada oligodendrócito forma um segmento de mielina para vários axônios adjacentes.<sup id="cite_ref-CarlsonPhysiology_1-1" class="reference"><a href="#cite_note-CarlsonPhysiology-1"><span>[</span>1<span>]</span></a></sup> </p><p>Os oligodendrócitos são encontrados apenas no sistema nervoso central, que compreende o cérebro e a medula espinhal. Originalmente, pensava-se que essas células eram produzidas no tubo neural ventral; no entanto, a pesquisa agora mostra que os oligodendrócitos se originam da zona ventricular ventral da medula espinhal embrionária e, possivelmente, têm algumas concentrações no prosencéfalo.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span>[</span>3<span>]</span></a></sup> Eles são o último tipo de célula a ser gerado no SNC.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span>[</span>4<span>]</span></a></sup> Os oligodendrócitos foram descobertos por <a href="/w/index.php?title=P%C3%ADo_del_R%C3%ADo_Hortega&action=edit&redlink=1" class="new" title="Pío del Río Hortega (página não existe)">Pío del Río Hortega</a>.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span>[</span>5<span>]</span></a></sup><sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span>[</span>6<span>]</span></a></sup> </p><p>Sem os oligodendrócitos, os neurônios não sobrevivem em meio de cultura. Em suas características físicas os oligodendrócitos mostram-se um corpo celular arredondado e pequeno, com poucos prolongamentos, curtos, finos e pouco ramificados (daí o nome: <i>oligo</i>= pouco; <i>dendro</i>= ramificação). Assim como em diversas células do corpo humano nos oligodendrócitos podem ser geradas <a href="/wiki/Neoplasia" title="Neoplasia">neoplasias</a> (tumores), que neste caso são os <a href="/wiki/Oligodedroglioma" title="Oligodedroglioma">oligodedrogliomas</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Classificação"><span id="Classifica.C3.A7.C3.A3o"></span>Classificação</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Oligodendr%C3%B3cito&veaction=edit&section=1" title="Editar secção: Classificação" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Oligodendr%C3%B3cito&action=edit&section=1" title="Editar código-fonte da secção: Classificação"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Os oligodendrócitos são um tipo de <a href="/wiki/C%C3%A9lula_da_glia" class="mw-redirect" title="Célula da glia">célula da glia</a>. Eles surgem durante o desenvolvimento de células precursoras de oligodendrócitos (OPCs),<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span>[</span>7<span>]</span></a></sup> que podem ser identificadas por sua expressão de uma série de <a href="/wiki/Ant%C3%ADgeno" title="Antígeno">antígenos</a>, incluindo o <a href="/wiki/Ganglios%C3%ADdio" title="Gangliosídio">gangliosídio</a> GD3,<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span>[</span>8<span>]</span></a></sup><sup id="cite_ref-Hardy1991_9-0" class="reference"><a href="#cite_note-Hardy1991-9"><span>[</span>9<span>]</span></a></sup>, o <a href="/w/index.php?title=CSPG4&action=edit&redlink=1" class="new" title="CSPG4 (página não existe)">proteoglicano de sulfato de condroitina G2</a>, e o <a href="/w/index.php?title=PDGFRA&action=edit&redlink=1" class="new" title="PDGFRA (página não existe)">receptor do fator de crescimento derivado de plaquetas</a> (PDGF-alphaR).<sup id="cite_ref-Pringle1992_10-0" class="reference"><a href="#cite_note-Pringle1992-10"><span>[</span>10<span>]</span></a></sup> Os oligodendrócitos maduros são amplamente classificados em oligodendrócitos satélites mielinizantes ou não mielinizantes. Os precursores e ambos os tipos maduros são tipicamente identificados por sua expressão do fator de transcrição <a href="/w/index.php?title=OLIG2&action=edit&redlink=1" class="new" title="OLIG2 (página não existe)">OLIG2</a>.<sup id="cite_ref-pmid15111318_11-0" class="reference"><a href="#cite_note-pmid15111318-11"><span>[</span>11<span>]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Desenvolvimento">Desenvolvimento</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Oligodendr%C3%B3cito&veaction=edit&section=2" title="Editar secção: Desenvolvimento" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Oligodendr%C3%B3cito&action=edit&section=2" title="Editar código-fonte da secção: Desenvolvimento"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>A maioria dos oligodendrócitos se desenvolve durante a <a href="/wiki/Embriog%C3%AAnese" class="mw-redirect" title="Embriogênese">embriogênese</a> e no início da vida pós-natal a partir de regiões germinativas periventriculares restritas.<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span>[</span>12<span>]</span></a></sup> A formação de oligodendrócitos no cérebro adulto está associada a células progenitoras restritas à glia, conhecidas como células progenitoras de oligodendrócitos (OPCs).<sup id="cite_ref-Menn2006_13-0" class="reference"><a href="#cite_note-Menn2006-13"><span>[</span>13<span>]</span></a></sup> As células da <a href="/w/index.php?title=Zona_subventricular&action=edit&redlink=1" class="new" title="Zona subventricular (página não existe)">zona subventricular</a> migram para longe das zonas <a href="/wiki/Folheto_embrion%C3%A1rio" title="Folheto embrionário">germinativas</a><sup id="cite_ref-Menn2006_13-1" class="reference"><a href="#cite_note-Menn2006-13"><span>[</span>13<span>]</span></a></sup> para preencher as substâncias <a href="/wiki/Subst%C3%A2ncia_branca" title="Substância branca">branca</a> e <a href="/wiki/Subst%C3%A2ncia_cinzenta" title="Substância cinzenta">cinzenta</a> em desenvolvimento, onde se diferenciam e amadurecem em oligodendrócitos formadores de mielina.<sup id="cite_ref-Hardy1991_9-1" class="reference"><a href="#cite_note-Hardy1991-9"><span>[</span>9<span>]</span></a></sup><sup id="cite_ref-14" class="reference"><a href="#cite_note-14"><span>[</span>14<span>]</span></a></sup> No entanto, não está claro se todos os progenitores de oligodendrócitos sofrem essa sequência de eventos. </p><p>Entre a gestação média e o nascimento a termo, três estágios sucessivos da linhagem clássica de oligodendrócitos humanos são encontrados na substância branca cerebral humana: OPCs, oligodendrócitos imaturos (não mielinizantes) e oligodendrócitos maduros (mielinizantes).<sup id="cite_ref-pmid24768715_15-0" class="reference"><a href="#cite_note-pmid24768715-15"><span>[</span>15<span>]</span></a></sup> Foi sugerido que alguns sofrem apoptose,<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span>[</span>16<span>]</span></a></sup> e outros não conseguem se diferenciar em oligodendrócitos maduros, mas persistem como OPCs adultos.<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span>[</span>17<span>]</span></a></sup> Notavelmente, a população de oligodendrócitos originada na zona subventricular pode ser dramaticamente expandida pela administração de <a href="/w/index.php?title=Fator_de_crescimento_epid%C3%A9rmico&action=edit&redlink=1" class="new" title="Fator de crescimento epidérmico (página não existe)">fator de crescimento epidérmico</a> (EGF).<sup id="cite_ref-Gonzalez-Perez2009_18-0" class="reference"><a href="#cite_note-Gonzalez-Perez2009-18"><span>[</span>18<span>]</span></a></sup><sup id="cite_ref-Gonzalez-Perez2011_19-0" class="reference"><a href="#cite_note-Gonzalez-Perez2011-19"><span>[</span>19<span>]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Função"><span id="Fun.C3.A7.C3.A3o"></span>Função</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Oligodendr%C3%B3cito&veaction=edit&section=3" title="Editar secção: Função" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Oligodendr%C3%B3cito&action=edit&section=3" title="Editar código-fonte da secção: Função"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Mielinização"><span id="Mieliniza.C3.A7.C3.A3o"></span>Mielinização</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Oligodendr%C3%B3cito&veaction=edit&section=4" title="Editar secção: Mielinização" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Oligodendr%C3%B3cito&action=edit&section=4" title="Editar código-fonte da secção: Mielinização"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/Ficheiro:Oligodendrocyte_illustration.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Oligodendrocyte_illustration.png/220px-Oligodendrocyte_illustration.png" decoding="async" width="220" height="175" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Oligodendrocyte_illustration.png/330px-Oligodendrocyte_illustration.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Oligodendrocyte_illustration.png/440px-Oligodendrocyte_illustration.png 2x" data-file-width="1146" data-file-height="913" /></a><figcaption>Um oligodendrócito mielinizando vários axônios.</figcaption></figure> <p>O <a href="/wiki/Sistema_nervoso" title="Sistema nervoso">sistema nervoso</a> dos mamíferos depende crucialmente das <a href="/wiki/Bainha_de_mielina" title="Bainha de mielina">bainhas de mielina</a>, que reduzem o vazamento de íons e diminuem a capacitância da <a href="/wiki/Membrana_celular" title="Membrana celular">membrana celular</a>, para uma rápida condução do impulso nervoso. A mielina também aumenta a velocidade do impulso, pois a propagação saltatória dos potenciais de ação ocorre nos nódulos de Ranvier entre as células de Schwann (do <a href="/wiki/Sistema_nervoso_perif%C3%A9rico" title="Sistema nervoso periférico">SNP</a>) e os oligodendrócitos (do <a href="/wiki/Sistema_nervoso_central" title="Sistema nervoso central">SNC</a>). Além disso, a velocidade de impulso dos axônios mielinizados aumenta linearmente com o diâmetro do axônio, enquanto a velocidade de impulso das células não mielinizadas aumenta apenas com a raiz quadrada do diâmetro. O isolamento deve ser proporcional ao diâmetro da fibra interna. A proporção ideal do diâmetro do axônio dividido pelo diâmetro total da fibra (que inclui a mielina) é de 0,6.<sup id="cite_ref-Fields_20-0" class="reference"><a href="#cite_note-Fields-20"><span>[</span>20<span>]</span></a></sup> </p><p>A mielinização é prevalente apenas em algumas regiões do cérebro no nascimento e continua na idade adulta. Todo o processo não está completo até cerca de 25-30 anos de idade.<sup id="cite_ref-Fields_20-1" class="reference"><a href="#cite_note-Fields-20"><span>[</span>20<span>]</span></a></sup> Ratos que foram criados em um ambiente enriquecido, que é conhecido por aumentar a flexibilidade cognitiva, tiveram mais mielinização no <a href="/wiki/Corpo_caloso" title="Corpo caloso">corpo caloso</a>.<sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span>[</span>21<span>]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Suporte_metabólico"><span id="Suporte_metab.C3.B3lico"></span>Suporte metabólico</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Oligodendr%C3%B3cito&veaction=edit&section=5" title="Editar secção: Suporte metabólico" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Oligodendr%C3%B3cito&action=edit&section=5" title="Editar código-fonte da secção: Suporte metabólico"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Os oligodendrócitos interagem intimamente com as células nervosas e fornecem suporte trófico pela produção de fator neurotrófico derivado da linha de células gliais (GDNF), fator neurotrófico derivado do cérebro (BDNF) ou fator de crescimento semelhante à insulina-1 (IGF-1).<sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span>[</span>22<span>]</span></a></sup> Eles também podem fornecer metabólitos diretamente aos neurônios, conforme descrito pela hipótese do transporte de lactato.<sup id="cite_ref-Philips2017_23-0" class="reference"><a href="#cite_note-Philips2017-23"><span>[</span>23<span>]</span></a></sup> </p><p>É hipotetizado que os oligodendrócitos satélite (ou oligodendrócitos perineuronais) são funcionalmente distintos de outros oligodendrócitos. Eles não estão ligados aos neurônios por meio de bainhas de mielina e, portanto, não contribuem para o isolamento. Eles permanecem opostos aos neurônios e regulam o fluido extracelular.<sup id="cite_ref-Baumann2011_2-1" class="reference"><a href="#cite_note-Baumann2011-2"><span>[</span>2<span>]</span></a></sup> Os oligodendrócitos satélite são considerados parte da substância cinzenta, enquanto os oligodendrócitos mielinizantes são parte da substância branca. Eles podem apoiar o metabolismo neuronal. Oligodendrócitos satélite podem ser recrutados para produzir nova mielina após uma lesão desmielinizante..<sup id="cite_ref-Szuchet2011_24-0" class="reference"><a href="#cite_note-Szuchet2011-24"><span>[</span>24<span>]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Significância_clínica"><span id="Signific.C3.A2ncia_cl.C3.ADnica"></span>Significância clínica</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Oligodendr%C3%B3cito&veaction=edit&section=6" title="Editar secção: Significância clínica" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Oligodendr%C3%B3cito&action=edit&section=6" title="Editar código-fonte da secção: Significância clínica"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>As doenças que resultam em lesão de oligodendrócitos incluem doenças desmielinizantes, como <a href="/wiki/Esclerose_m%C3%BAltipla" title="Esclerose múltipla">esclerose múltipla</a> e várias <a href="/wiki/Leucodistrofia" title="Leucodistrofia">leucodistrofias</a>. Trauma no corpo (por ex. lesão da medula espinhal) também pode causar desmielinização. Os oligodendrócitos imaturos, que aumentam em número durante o meio da gestação, são mais vulneráveis a lesões por hipóxia e estão envolvidos na leucomalácia periventricular.<sup id="cite_ref-pmid9777676_25-0" class="reference"><a href="#cite_note-pmid9777676-25"><span>[</span>25<span>]</span></a></sup> A disfunção de oligodendrócitos também pode estar implicada na fisiopatologia da <a href="/wiki/Esquizofrenia" title="Esquizofrenia">esquizofrenia</a> e <a href="/wiki/Transtorno_bipolar" title="Transtorno bipolar">transtorno bipolar</a>.<sup id="cite_ref-26" class="reference"><a href="#cite_note-26"><span>[</span>26<span>]</span></a></sup> </p><p>Os oligodendrócitos também são suscetíveis à infecção pelo <a href="/wiki/V%C3%ADrus_JC" title="Vírus JC">vírus JC</a>, que causa <a href="/wiki/Leucoencefalopatia_multifocal_progressiva" title="Leucoencefalopatia multifocal progressiva">leucoencefalopatia multifocal progressiva</a> (LMP), uma condição que afeta especificamente a substância branca, geralmente em pacientes imunocomprometidos. Os <a href="/wiki/Tumor" class="mw-redirect" title="Tumor">tumores</a> de oligodendrócitos são chamados de <a href="/wiki/Oligodendroglioma" title="Oligodendroglioma">oligodendrogliomas</a>. O agente quimioterápico <a href="/wiki/Fluorouracil" title="Fluorouracil">Fluorouracil</a> (5-FU) causa danos aos oligodendrócitos em camundongos, causando danos agudos ao sistema nervoso central (SNC) e piora progressiva da degeneração do SNC.<sup id="cite_ref-27" class="reference"><a href="#cite_note-27"><span>[</span>27<span>]</span></a></sup><sup id="cite_ref-28" class="reference"><a href="#cite_note-28"><span>[</span>28<span>]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Ver_também"><span id="Ver_tamb.C3.A9m"></span>Ver também</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Oligodendr%C3%B3cito&veaction=edit&section=7" title="Editar secção: Ver também" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Oligodendr%C3%B3cito&action=edit&section=7" title="Editar código-fonte da secção: Ver também"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Subst%C3%A2ncia_branca" title="Substância branca">Substância branca</a></li> <li><a href="/wiki/C%C3%A9lulas_de_Schwann" class="mw-redirect" title="Células de Schwann">Células de Schwann</a></li></ul> <h2 id="Referências" style="cursor: help;" title="Esta seção foi configurada para não ser editável diretamente. Edite a página toda ou a seção anterior em vez disso."><span id="Refer.C3.AAncias"></span>Referências</h2> <div class="reflist" style="list-style-type: decimal;"><div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-CarlsonPhysiology-1"><span class="mw-cite-backlink">↑ <sup><i><b><a href="#cite_ref-CarlsonPhysiology_1-0">a</a></b></i></sup> <sup><i><b><a href="#cite_ref-CarlsonPhysiology_1-1">b</a></b></i></sup></span> <span class="reference-text"><cite class="citation book">Carlson, Neil (2010). <i>Physiology of Behavior</i>. Boston, MA: Allyn & Bacon. pp. 38–39. <a href="/wiki/International_Standard_Book_Number" title="International Standard Book Number">ISBN</a> <a href="/wiki/Especial:Fontes_de_livros/978-0-205-66627-0" title="Especial:Fontes de livros/978-0-205-66627-0">978-0-205-66627-0</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.aufirst=Neil&rft.aulast=Carlson&rft.btitle=Physiology+of+Behavior&rft.date=2010&rft.genre=book&rft.isbn=978-0-205-66627-0&rft.pages=38-39&rft.place=Boston%2C+MA&rft.pub=Allyn+%26+Bacon&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Baumann2011-2"><span class="mw-cite-backlink">↑ <sup><i><b><a href="#cite_ref-Baumann2011_2-0">a</a></b></i></sup> <sup><i><b><a href="#cite_ref-Baumann2011_2-1">b</a></b></i></sup></span> <span class="reference-text"><cite class="citation journal">Baumann, Nicole; Pham-Dinh, Danielle (1 de abril de 2001). «Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System». <i>Physiological Reviews</i> (em inglês). <b>81</b> (2): 871–927. <a href="/wiki/International_Standard_Serial_Number" title="International Standard Serial Number">ISSN</a> <a rel="nofollow" class="external text" href="//www.worldcat.org/issn/0031-9333">0031-9333</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/11274346">11274346</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1152%2Fphysrev.2001.81.2.871">10.1152/physrev.2001.81.2.871</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Biology+of+Oligodendrocyte+and+Myelin+in+the+Mammalian+Central+Nervous+System&rft.au=Pham-Dinh%2C+Danielle&rft.aufirst=Nicole&rft.aulast=Baumann&rft.date=2001-04-01&rft.genre=article&rft.issn=0031-9333&rft.issue=2&rft.jtitle=Physiological+Reviews&rft.pages=871-927&rft.volume=81&rft_id=info%3Adoi%2F10.1152%2Fphysrev.2001.81.2.871&rft_id=info%3Apmid%2F11274346&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><a href="#cite_ref-3">↑</a></span> <span class="reference-text"><cite class="citation journal">Richardson, WD; Kessaris, N; Pringle, N (2006). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC6328010">«Oligodendrocyte wars.»</a>. <i>Nature Reviews. Neuroscience</i>. <b>7</b> (1): 11–8. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC6328010">6328010</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16371946">16371946</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnrn1826">10.1038/nrn1826</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Oligodendrocyte+wars.&rft.au=Kessaris%2C+N&rft.au=Pringle%2C+N&rft.aufirst=WD&rft.aulast=Richardson&rft.date=2006&rft.genre=article&rft.issue=1&rft.jtitle=Nature+Reviews.+Neuroscience&rft.pages=11-8&rft.volume=7&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6328010&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6328010&rft_id=info%3Adoi%2F10.1038%2Fnrn1826&rft_id=info%3Apmid%2F16371946&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text"><cite class="citation journal">Thomas, JL; Spassky, N; Perez Villegas, EM; Olivier, C; Cobos, I; Goujet-Zalc, C; Martínez, S; Zalc, B (2000). «Spatiotemporal development of oligodendrocytes in the embryonic brain». <i>Journal of Neuroscience Research</i>. <b>59</b> (4): 471–6. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/10679785">10679785</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1002%2F%28SICI%291097-4547%2820000215%2959%3A4%3C471%3A%3AAID-JNR1%3E3.0.CO%3B2-3">10.1002/(SICI)1097-4547(20000215)59:4<471::AID-JNR1>3.0.CO;2-3</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Spatiotemporal+development+of+oligodendrocytes+in+the+embryonic+brain&rft.au=Cobos%2C+I&rft.au=Goujet-Zalc%2C+C&rft.au=Mart%C3nez%2C+S&rft.au=Olivier%2C+C&rft.au=Perez+Villegas%2C+EM&rft.au=Spassky%2C+N&rft.au=Zalc%2C+B&rft.aufirst=JL&rft.aulast=Thomas&rft.date=2000&rft.genre=article&rft.issue=4&rft.jtitle=Journal+of+Neuroscience+Research&rft.pages=471-6&rft.volume=59&rft_id=info%3Adoi%2F10.1002%2F%28SICI%291097-4547%2820000215%2959%3A4%3C471%3A%3AAID-JNR1%3E3.0.CO%3B2-3&rft_id=info%3Apmid%2F10679785&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text"><cite class="citation journal">Pérez-Cerdá, Fernando; Sánchez-Gómez, María Victoria; Matute, Carlos (2015). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC4493393">«Pío del Río Hortega and the discovery of the oligodendrocytes»</a>. <i>Frontiers in Neuroanatomy</i> (em inglês). <b>9</b>. 92 páginas. <a href="/wiki/International_Standard_Serial_Number" title="International Standard Serial Number">ISSN</a> <a rel="nofollow" class="external text" href="//www.worldcat.org/issn/1662-5129">1662-5129</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC4493393">4493393</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/26217196">26217196</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.3389%2Ffnana.2015.00092">10.3389/fnana.2015.00092</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=P%C3o+del+R%C3o+Hortega+and+the+discovery+of+the+oligodendrocytes&rft.au=Matute%2C+Carlos&rft.au=S%C3%A1nchez-G%C3%B3mez%2C+Mar%C3a+Victoria&rft.aufirst=Fernando&rft.aulast=P%C3%A9rez-Cerd%C3%A1&rft.date=2015&rft.genre=article&rft.issn=1662-5129&rft.jtitle=Frontiers+in+Neuroanatomy&rft.volume=9&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4493393&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4493393&rft_id=info%3Adoi%2F10.3389%2Ffnana.2015.00092&rft_id=info%3Apmid%2F26217196&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><a href="#cite_ref-6">↑</a></span> <span class="reference-text"><cite class="citation journal">James, Owen G; Mehta, Arpan R; Behari, Madhuri; Chandran, Siddharthan (2021). <a rel="nofollow" class="external text" href="https://linkinghub.elsevier.com/retrieve/pii/S1474442221001368">«Centenary of the oligodendrocyte»</a>. <i>The Lancet Neurology</i> (em inglês). <b>20</b> (6). 422 páginas. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2FS1474-4422%2821%2900136-8">10.1016/S1474-4422(21)00136-8</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Centenary+of+the+oligodendrocyte&rft.au=Behari%2C+Madhuri&rft.au=Chandran%2C+Siddharthan&rft.au=Mehta%2C+Arpan+R&rft.aufirst=Owen+G&rft.aulast=James&rft.date=2021&rft.genre=article&rft.issue=6&rft.jtitle=The+Lancet+Neurology&rft.volume=20&rft_id=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1474442221001368&rft_id=info%3Adoi%2F10.1016%2FS1474-4422%2821%2900136-8&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><a href="#cite_ref-7">↑</a></span> <span class="reference-text"><cite class="citation journal">Cameron-Curry, Patrizia; Le Douarin, Nicole M. (1995). «Oligodendrocyte precursors originate from both the dorsal and the ventral parts of the spinal cord». <i>Neuron</i>. <b>15</b> (6): 1299–1310. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/8845154">8845154</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2F0896-6273%2895%2990009-8">10.1016/0896-6273(95)90009-8</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Oligodendrocyte+precursors+originate+from+both+the+dorsal+and+the+ventral+parts+of+the+spinal+cord&rft.au=Le+Douarin%2C+Nicole+M.&rft.aufirst=Patrizia&rft.aulast=Cameron-Curry&rft.date=1995&rft.genre=article&rft.issue=6&rft.jtitle=Neuron&rft.pages=1299-1310&rft.volume=15&rft_id=info%3Adoi%2F10.1016%2F0896-6273%2895%2990009-8&rft_id=info%3Apmid%2F8845154&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><a href="#cite_ref-8">↑</a></span> <span class="reference-text"><cite class="citation journal">LeVine, S. M.; Goldman, J. E. (1988). «Spatial and temporal patterns of oligodendrocyte differentiation in rat cerebrum and cerebellum». <i>The Journal of comparative neurology</i>. <b>277</b> (3): 441–455. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1002%2Fcne.902770309">10.1002/cne.902770309</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Spatial+and+temporal+patterns+of+oligodendrocyte+differentiation+in+rat+cerebrum+and+cerebellum&rft.au=Goldman%2C+J.+E.&rft.au=LeVine%2C+S.+M.&rft.date=1988&rft.genre=article&rft.issue=3&rft.jtitle=The+Journal+of+comparative+neurology&rft.pages=441-455&rft.volume=277&rft_id=info%3Adoi%2F10.1002%2Fcne.902770309&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Hardy1991-9"><span class="mw-cite-backlink">↑ <sup><i><b><a href="#cite_ref-Hardy1991_9-0">a</a></b></i></sup> <sup><i><b><a href="#cite_ref-Hardy1991_9-1">b</a></b></i></sup></span> <span class="reference-text"><cite class="citation journal">Hardy, R.; Reynolds, R. (1991). «Proliferation and differentiation potential of rat forebrain oligodendroglial progenitors both in vitro and in vivo.». <i>Development</i>. <b>111</b> (4): 1061-1080</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Proliferation+and+differentiation+potential+of+rat+forebrain+oligodendroglial+progenitors+both+in+vitro+and+in+vivo.&rft.au=Hardy%2C+R.&rft.au=Reynolds%2C+R.&rft.date=1991&rft.genre=article&rft.issue=4&rft.jtitle=Development&rft.pages=1061-1080&rft.volume=111&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Pringle1992-10"><span class="mw-cite-backlink"><a href="#cite_ref-Pringle1992_10-0">↑</a></span> <span class="reference-text"><cite class="citation journal">Pringle, N.P.; Mudhar, H.S.; Collarini, E.J.; Richardson, WD (1992). <a rel="nofollow" class="external text" href="http://dev.biologists.org/content/115/2/535.full.pdf">«PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage.»</a> <span style="font-size:85%;">(PDF)</span>. <i>Development</i>. <b>115</b> (2): 535–51. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/1425339">1425339</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=PDGF+receptors+in+the+rat+CNS%3A+during+late+neurogenesis%2C+PDGF+alpha-receptor+expression+appears+to+be+restricted+to+glial+cells+of+the+oligodendrocyte+lineage.&rft.au=Collarini%2C+E.J.&rft.au=Mudhar%2C+H.S.&rft.au=Richardson%2C+WD&rft.aufirst=N.P.&rft.aulast=Pringle&rft.date=1992&rft.genre=article&rft.issue=2&rft.jtitle=Development&rft.pages=535-51&rft.volume=115&rft_id=http%3A%2F%2Fdev.biologists.org%2Fcontent%2F115%2F2%2F535.full.pdf&rft_id=info%3Apmid%2F1425339&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid15111318-11"><span class="mw-cite-backlink"><a href="#cite_ref-pmid15111318_11-0">↑</a></span> <span class="reference-text"><cite class="citation journal">Yokoo, H.; Nobusawa, S.; Takebayashi, H.; Ikenaka, K.; Isoda, K.; Kamiya, M.; Sasaki, A.; Hirato, J.; Nakazato, Y. (2004). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1615653">«Anti-human Olig2 antibody as a useful immunohistochemical marker of normal oligodendrocytes and gliomas.»</a>. <i>Am J Pathol</i>. <b>164</b> (5): 1717–25. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1615653">1615653</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15111318">15111318</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2FS0002-9440%2810%2963730-3">10.1016/S0002-9440(10)63730-3</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Anti-human+Olig2+antibody+as+a+useful+immunohistochemical+marker+of+normal+oligodendrocytes+and+gliomas.&rft.au=Yokoo%2C+H.%3B+Nobusawa%2C+S.%3B+Takebayashi%2C+H.%3B+Ikenaka%2C+K.%3B+Isoda%2C+K.%3B+Kamiya%2C+M.%3B+Sasaki%2C+A.%3B+Hirato%2C+J.%3B+Nakazato%2C+Y.&rft.date=2004&rft.genre=article&rft.issue=5&rft.jtitle=Am+J+Pathol&rft.pages=1717-25&rft.volume=164&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1615653&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1615653&rft_id=info%3Adoi%2F10.1016%2FS0002-9440%2810%2963730-3&rft_id=info%3Apmid%2F15111318&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33"> !CS1 manut: Nomes múltiplos: lista de autores (<a href="/wiki/Categoria:!CS1_manut:_Nomes_m%C3%BAltiplos:_lista_de_autores" title="Categoria:!CS1 manut: Nomes múltiplos: lista de autores">link</a>)</span></span> </li> <li id="cite_note-12"><span class="mw-cite-backlink"><a href="#cite_ref-12">↑</a></span> <span class="reference-text"><cite class="citation journal">Vallstedt, Anna; M.Klos,Joanna; =Ericson, Johan (2005). «Multiple Dorsoventral Origins of Oligodendrocyte Generation in the Spinal Cord and Hindbrain». <i>Neuron</i>. <b>45</b> (1): 55-67. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.neuron.2004.12.026">10.1016/j.neuron.2004.12.026</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Multiple+Dorsoventral+Origins+of+Oligodendrocyte+Generation+in+the+Spinal+Cord+and+Hindbrain&rft.au=%3DEricson%2C+Johan&rft.au=M.Klos%2CJoanna&rft.au=Vallstedt%2C+Anna&rft.date=2005&rft.genre=article&rft.issue=1&rft.jtitle=Neuron&rft.pages=55-67&rft.volume=45&rft_id=info%3Adoi%2F10.1016%2Fj.neuron.2004.12.026&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Menn2006-13"><span class="mw-cite-backlink">↑ <sup><i><b><a href="#cite_ref-Menn2006_13-0">a</a></b></i></sup> <sup><i><b><a href="#cite_ref-Menn2006_13-1">b</a></b></i></sup></span> <span class="reference-text"><cite class="citation journal">Menn, B; Garcia-Verdugo, JM; Yaschine, C; Gonzalez-Perez, O; Rowitch, D; Alvarez-Buylla, A (2006). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC6674207">«Origin of oligodendrocytes in the subventricular zone of the adult brain.»</a>. <i>The Journal of Neuroscience</i>. <b>26</b> (30): 7907–18. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC6674207">6674207</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16870736">16870736</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1523%2FJNEUROSCI.1299-06.2006">10.1523/JNEUROSCI.1299-06.2006</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Origin+of+oligodendrocytes+in+the+subventricular+zone+of+the+adult+brain.&rft.au=Alvarez-Buylla%2C+A&rft.au=Garcia-Verdugo%2C+JM&rft.au=Gonzalez-Perez%2C+O&rft.au=Rowitch%2C+D&rft.au=Yaschine%2C+C&rft.aufirst=B&rft.aulast=Menn&rft.date=2006&rft.genre=article&rft.issue=30&rft.jtitle=The+Journal+of+Neuroscience&rft.pages=7907-18&rft.volume=26&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6674207&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6674207&rft_id=info%3Adoi%2F10.1523%2FJNEUROSCI.1299-06.2006&rft_id=info%3Apmid%2F16870736&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-14"><span class="mw-cite-backlink"><a href="#cite_ref-14">↑</a></span> <span class="reference-text"><cite class="citation journal">Levison, S.W.; Goldman, J.E. (1991). «Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain». <i>Neuron</i>. <b>10</b> (2): 201-212. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2F0896-6273%2893%2990311-e">10.1016/0896-6273(93)90311-e</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Both+oligodendrocytes+and+astrocytes+develop+from+progenitors+in+the+subventricular+zone+of+postnatal+rat+forebrain&rft.au=Goldman%2C+J.E.&rft.au=Levison%2C+S.W.&rft.date=1991&rft.genre=article&rft.issue=2&rft.jtitle=Neuron&rft.pages=201-212&rft.volume=10&rft_id=info%3Adoi%2F10.1016%2F0896-6273%2893%2990311-e&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid24768715-15"><span class="mw-cite-backlink"><a href="#cite_ref-pmid24768715_15-0">↑</a></span> <span class="reference-text"><cite class="citation journal">Barateiro, Andreia; Fernandes, Adelaide (2014). «Temporal oligodendrocyte lineage progression: In vitro models of proliferation, differentiation and myelination». <i>Biochimica et Biophysica Acta (BBA) - Molecular Cell Research</i>. <b>1843</b> (9): 1917–1929. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/24768715">24768715</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.bbamcr.2014.04.018">10.1016/j.bbamcr.2014.04.018</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Temporal+oligodendrocyte+lineage+progression%3A+In+vitro+models+of+proliferation%2C+differentiation+and+myelination&rft.au=Fernandes%2C+Adelaide&rft.aufirst=Andreia&rft.aulast=Barateiro&rft.date=2014&rft.genre=article&rft.issue=9&rft.jtitle=Biochimica+et+Biophysica+Acta+%28BBA%29+-+Molecular+Cell+Research&rft.pages=1917-1929&rft.volume=1843&rft_id=info%3Adoi%2F10.1016%2Fj.bbamcr.2014.04.018&rft_id=info%3Apmid%2F24768715&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span typeof="mw:File"><a href="/wiki/Acesso_livre" title="publicação de acesso livre - leitura gratuita"><img alt="publicação de acesso livre - leitura gratuita" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/77/Open_Access_logo_PLoS_transparent.svg/8px-Open_Access_logo_PLoS_transparent.svg.png" decoding="async" width="8" height="13" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/77/Open_Access_logo_PLoS_transparent.svg/12px-Open_Access_logo_PLoS_transparent.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/77/Open_Access_logo_PLoS_transparent.svg/16px-Open_Access_logo_PLoS_transparent.svg.png 2x" data-file-width="640" data-file-height="1000" /></a></span></span> </li> <li id="cite_note-16"><span class="mw-cite-backlink"><a href="#cite_ref-16">↑</a></span> <span class="reference-text"><cite class="citation journal">Barres, B. A., Hart, I. K., Coles, H. S., Burne, J. F., Voyvodic, J. T., Richardson, W. D., & Raff, M. C. (1992). «Cell death and control of cell survival in the oligodendrocyte lineage». <i>Cell</i>. <b>70</b> (1): 31–46. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2F0092-8674%2892%2990531-g">10.1016/0092-8674(92)90531-g</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Cell+death+and+control+of+cell+survival+in+the+oligodendrocyte+lineage&rft.au=Barres%2C+B.+A.%2C+Hart%2C+I.+K.%2C+Coles%2C+H.+S.%2C+Burne%2C+J.+F.%2C+Voyvodic%2C+J.+T.%2C+Richardson%2C+W.+D.%2C+%26+Raff%2C+M.+C.&rft.date=1992&rft.genre=article&rft.issue=1&rft.jtitle=Cell&rft.pages=31-46&rft.volume=70&rft_id=info%3Adoi%2F10.1016%2F0092-8674%2892%2990531-g&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33"> !CS1 manut: Nomes múltiplos: lista de autores (<a href="/wiki/Categoria:!CS1_manut:_Nomes_m%C3%BAltiplos:_lista_de_autores" title="Categoria:!CS1 manut: Nomes múltiplos: lista de autores">link</a>)</span></span> </li> <li id="cite_note-17"><span class="mw-cite-backlink"><a href="#cite_ref-17">↑</a></span> <span class="reference-text">Wren et al., 1992</span> </li> <li id="cite_note-Gonzalez-Perez2009-18"><span class="mw-cite-backlink"><a href="#cite_ref-Gonzalez-Perez2009_18-0">↑</a></span> <span class="reference-text"><cite class="citation journal">Gonzalez-Perez, O, B; Romero-Rodriguez, R; Soriano-Navarro, M; Garcia-Verdugo, JM; Alvarez-Buylla, A (2009). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3346259">«Epidermal growth factor induces the progeny of subventricular zone type B cells to migrate and differentiate into oligodendrocytes»</a>. <i>Stem Cells</i>. <b>27</b> (8): 2032–43. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3346259">3346259</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/19544429">19544429</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1002%2Fstem.119">10.1002/stem.119</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Epidermal+growth+factor+induces+the+progeny+of+subventricular+zone+type+B+cells+to+migrate+and+differentiate+into+oligodendrocytes&rft.au=Alvarez-Buylla%2C+A&rft.au=Garcia-Verdugo%2C+JM&rft.au=Romero-Rodriguez%2C+R&rft.au=Soriano-Navarro%2C+M&rft.aufirst=B&rft.aulast=Gonzalez-Perez%2C+O&rft.date=2009&rft.genre=article&rft.issue=8&rft.jtitle=Stem+Cells&rft.pages=2032-43&rft.volume=27&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3346259&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3346259&rft_id=info%3Adoi%2F10.1002%2Fstem.119&rft_id=info%3Apmid%2F19544429&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Gonzalez-Perez2011-19"><span class="mw-cite-backlink"><a href="#cite_ref-Gonzalez-Perez2011_19-0">↑</a></span> <span class="reference-text"><cite class="citation journal">Gonzalez-Perez, O., B.; Alvarez-Buylla, A. (2011). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3109119">«Oligodendrogenesis in the subventricular zone and the role of epidermal growth factor»</a>. <i>Brain Research Reviews</i>. <b>67</b> (1–2): 147–56. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3109119">3109119</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/21236296">21236296</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.brainresrev.2011.01.001">10.1016/j.brainresrev.2011.01.001</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Oligodendrogenesis+in+the+subventricular+zone+and+the+role+of+epidermal+growth+factor&rft.au=Alvarez-Buylla%2C+A.&rft.aufirst=B.&rft.aulast=Gonzalez-Perez%2C+O.&rft.date=2011&rft.genre=article&rft.issue=1%932&rft.jtitle=Brain+Research+Reviews&rft.pages=147-56&rft.volume=67&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3109119&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3109119&rft_id=info%3Adoi%2F10.1016%2Fj.brainresrev.2011.01.001&rft_id=info%3Apmid%2F21236296&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Fields-20"><span class="mw-cite-backlink">↑ <sup><i><b><a href="#cite_ref-Fields_20-0">a</a></b></i></sup> <sup><i><b><a href="#cite_ref-Fields_20-1">b</a></b></i></sup></span> <span class="reference-text"><cite class="citation journal">Fields, Douglas (2008). «White Matter Matters». <i>Scientific American</i>. <b>298</b> (March 2008): 54–61. <a href="/wiki/Bibcode" title="Bibcode">Bibcode</a>:<a rel="nofollow" class="external text" href="http://ui.adsabs.harvard.edu/abs/2008SciAm.298c..54D">2008SciAm.298c..54D</a>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18357821">18357821</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fscientificamerican0308-54">10.1038/scientificamerican0308-54</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=White+Matter+Matters&rft.aufirst=Douglas&rft.aulast=Fields&rft.date=2008&rft.genre=article&rft.issue=March+2008&rft.jtitle=Scientific+American&rft.pages=54-61&rft.volume=298&rft_id=info%3Abibcode%2F2008SciAm.298c..54D&rft_id=info%3Adoi%2F10.1038%2Fscientificamerican0308-54&rft_id=info%3Apmid%2F18357821&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-21"><span class="mw-cite-backlink"><a href="#cite_ref-21">↑</a></span> <span class="reference-text"><cite class="citation journal">Juraska, J. 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(1988). «Sex and environmental influences on the size and ultrastructure of the rat corpus callosum». <i>Brain Research</i>. <b>450</b> (1–2): 1–8. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/3401704">3401704</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2F0006-8993%2888%2991538-7">10.1016/0006-8993(88)91538-7</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Sex+and+environmental+influences+on+the+size+and+ultrastructure+of+the+rat+corpus+callosum&rft.au=Juraska%2C+J.+M.&rft.au=Kopcik%2C+J.+R.&rft.date=1988&rft.genre=article&rft.issue=1%932&rft.jtitle=Brain+Research&rft.pages=1-8&rft.volume=450&rft_id=info%3Adoi%2F10.1016%2F0006-8993%2888%2991538-7&rft_id=info%3Apmid%2F3401704&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-22"><span class="mw-cite-backlink"><a href="#cite_ref-22">↑</a></span> <span class="reference-text"><cite class="citation journal">Bradl, M. (2010). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2799635">«Oligodendrocytes: biology and pathology»</a>. <i>Acta Neuropathol</i>. <b>119</b> (1): 37–53. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2799635">2799635</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/19847447">19847447</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1007%2Fs00401-009-0601-5">10.1007/s00401-009-0601-5</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Oligodendrocytes%3A+biology+and+pathology&rft.au=Bradl%2C+M.&rft.date=2010&rft.genre=article&rft.issue=1&rft.jtitle=Acta+Neuropathol.&rft.pages=37-53&rft.volume=119&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2799635&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2799635&rft_id=info%3Adoi%2F10.1007%2Fs00401-009-0601-5&rft_id=info%3Apmid%2F19847447&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Philips2017-23"><span class="mw-cite-backlink"><a href="#cite_ref-Philips2017_23-0">↑</a></span> <span class="reference-text"><cite class="citation journal">Philips, T; Rothstein, J.D. (2017). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC5669561">«Oligodendroglia: metabolic supporters of neurons.»</a>. <i>J Clin Invest</i>. <b>127</b> (9): 3271–3280. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC5669561">5669561</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/28862639">28862639</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1172%2FJCI90610">10.1172/JCI90610</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Oligodendroglia%3A+metabolic+supporters+of+neurons.&rft.au=Philips%2C+T&rft.au=Rothstein%2C+J.D.&rft.date=2017&rft.genre=article&rft.issue=9&rft.jtitle=J+Clin+Invest&rft.pages=3271-3280&rft.volume=127&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5669561&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5669561&rft_id=info%3Adoi%2F10.1172%2FJCI90610&rft_id=info%3Apmid%2F28862639&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-Szuchet2011-24"><span class="mw-cite-backlink"><a href="#cite_ref-Szuchet2011_24-0">↑</a></span> <span class="reference-text"><cite class="citation journal">Szuchet, S.; Nielsen, J.A.; Lovas, G.; Domowicz M.S.; de Velasco, J.M.; Maric, D.; Hudson, L.D. (2011). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC4286392">«The genetic signature of perineuronal oligodendrocytes reveals their unique phenotype.»</a>. <i>Eur J Neurosci</i>. <b>34</b> (12): 1906–22. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC4286392">4286392</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/22132705">22132705</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1111%2Fj.1460-9568.2011.07922.x">10.1111/j.1460-9568.2011.07922.x</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=The+genetic+signature+of+perineuronal+oligodendrocytes+reveals+their+unique+phenotype.&rft.au=Domowicz+M.S.&rft.au=Hudson%2C+L.D.&rft.au=Lovas%2C+G.&rft.au=Maric%2C+D.&rft.au=Nielsen%2C+J.A.&rft.au=Szuchet%2C+S.&rft.au=de+Velasco%2C+J.M.&rft.date=2011&rft.genre=article&rft.issue=12&rft.jtitle=Eur+J+Neurosci&rft.pages=1906-22&rft.volume=34&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4286392&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4286392&rft_id=info%3Adoi%2F10.1111%2Fj.1460-9568.2011.07922.x&rft_id=info%3Apmid%2F22132705&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid9777676-25"><span class="mw-cite-backlink"><a href="#cite_ref-pmid9777676_25-0">↑</a></span> <span class="reference-text"><cite class="citation journal">Kinney, HC; Back, SA (1998). «Human oligodendroglial development: relationship to periventricular leukomalacia.». <i>Seminars in Pediatric Neurology</i>. <b>5</b> (3): 180–9. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/9777676">9777676</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fs1071-9091%2898%2980033-8">10.1016/s1071-9091(98)80033-8</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Human+oligodendroglial+development%3A+relationship+to+periventricular+leukomalacia.&rft.au=Back%2C+SA&rft.aufirst=HC&rft.aulast=Kinney&rft.date=1998&rft.genre=article&rft.issue=3&rft.jtitle=Seminars+in+Pediatric+Neurology&rft.pages=180-9&rft.volume=5&rft_id=info%3Adoi%2F10.1016%2Fs1071-9091%2898%2980033-8&rft_id=info%3Apmid%2F9777676&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-26"><span class="mw-cite-backlink"><a href="#cite_ref-26">↑</a></span> <span class="reference-text"><cite class="citation journal">Tkachev, D.; Mimmack, M.L.; Ryan, M.M. (2003). «Oligodendrocyte dysfunction in schizophrenia and bipolar disorder». <i>Lancet</i>. <b>362</b> (9386): 798–805. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/13678875">13678875</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2FS0140-6736%2803%2914289-4">10.1016/S0140-6736(03)14289-4</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Oligodendrocyte+dysfunction+in+schizophrenia+and+bipolar+disorder&rft.au=Tkachev%2C+D.%3B+Mimmack%2C+M.L.%3B+Ryan%2C+M.M.&rft.date=2003&rft.genre=article&rft.issue=9386&rft.jtitle=Lancet&rft.pages=798-805&rft.volume=362&rft_id=info%3Adoi%2F10.1016%2FS0140-6736%2803%2914289-4&rft_id=info%3Apmid%2F13678875&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33"> !CS1 manut: Nomes múltiplos: lista de autores (<a href="/wiki/Categoria:!CS1_manut:_Nomes_m%C3%BAltiplos:_lista_de_autores" title="Categoria:!CS1 manut: Nomes múltiplos: lista de autores">link</a>)</span></span> </li> <li id="cite_note-27"><span class="mw-cite-backlink"><a href="#cite_ref-27">↑</a></span> <span class="reference-text"><cite class="citation web">Dr. Mark D. Noble (27 de dezembro de 2011). <a rel="nofollow" class="external text" href="http://www.urmc.rochester.edu/biomedical-genetics/faculty/chemotherapy-induced-damage-to-cns.cfm">«Chemotherapy-induced Damage to the CNS as a Precursor Cell Disease»</a>. University of Rochester. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20111227061529/http://www.urmc.rochester.edu/biomedical-genetics/faculty/chemotherapy-induced-damage-to-cns.cfm">Cópia arquivada em 27 de dezembro de 2011</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.au=Dr.+Mark+D.+Noble&rft.btitle=Chemotherapy-induced+Damage+to+the+CNS+as+a+Precursor+Cell+Disease&rft.date=2011-12-27&rft.genre=unknown&rft.pub=University+of+Rochester&rft_id=http%3A%2F%2Fwww.urmc.rochester.edu%2Fbiomedical-genetics%2Ffaculty%2Fchemotherapy-induced-damage-to-cns.cfm&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-28"><span class="mw-cite-backlink"><a href="#cite_ref-28">↑</a></span> <span class="reference-text"><cite class="citation journal">Han, R; Yang, Y. M.; Dietrich, J.; Luebke, A.; Mayer-Pröschel, M.; Noble, M. (2008). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2397490">«Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system»</a>. <i>Journal of Biology</i>. <b>7</b> (4): 12. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2397490">2397490</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18430259">18430259</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1186%2Fjbiol69">10.1186/jbiol69</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Systemic+5-fluorouracil+treatment+causes+a+syndrome+of+delayed+myelin+destruction+in+the+central+nervous+system&rft.au=Dietrich%2C+J.&rft.au=Luebke%2C+A.&rft.au=Mayer-Pr%C3%B6schel%2C+M.&rft.au=Noble%2C+M.&rft.au=Yang%2C+Y.+M.&rft.aufirst=R&rft.aulast=Han&rft.date=2008&rft.genre=article&rft.issue=4&rft.jtitle=Journal+of+Biology&rft.pages=12&rft.volume=7&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2397490&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2397490&rft_id=info%3Adoi%2F10.1186%2Fjbiol69&rft_id=info%3Apmid%2F18430259&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Bibliografia">Bibliografia</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Oligodendr%C3%B3cito&veaction=edit&section=8" title="Editar secção: Bibliografia" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Oligodendr%C3%B3cito&action=edit&section=8" title="Editar código-fonte da secção: Bibliografia"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r60995074">.mw-parser-output .refbegin{font-size:90%;margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{list-style-type:none;margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li,.mw-parser-output .refbegin-hanging-indents>dl>dd{margin-left:0;padding-left:3.2em;text-indent:-3.2em;list-style:none}.mw-parser-output .refbegin-100{font-size:100%}</style><div class="refbegin reflist columns references-column-width" style="-moz-column-width: 30em; -webkit-column-width: 30em; column-width: 30em;"> <ul><li>Raine, C.S. (1991). Oligodendrocytes and central nervous system myelin. In Textbook of Neuropathology, second edition, R.L. Davis and D.M. Robertson, eds. (Baltimore, Maryland: Williams and Wilkins), pp. 115–141.</li> <li><cite class="citation journal">Káradóttir, R.; D. Attwell (2007). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2173944">«Neurotransmiter receptors in the life and death of oligodendrocytes»</a>. <i>Neuroscience</i>. <b>145</b> (4): 1426–1438. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2173944">2173944</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/17049173">17049173</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.neuroscience.2006.08.070">10.1016/j.neuroscience.2006.08.070</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Neurotransmiter+receptors+in+the+life+and+death+of+oligodendrocytes&rft.au=D.+Attwell&rft.aufirst=R.&rft.aulast=K%C3%A1rad%C3%B3ttir&rft.date=2007&rft.genre=article&rft.issue=4&rft.jtitle=Neuroscience&rft.pages=1426-1438&rft.volume=145&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2173944&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2173944&rft_id=info%3Adoi%2F10.1016%2Fj.neuroscience.2006.08.070&rft_id=info%3Apmid%2F17049173&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Gonzalez-Perez, O, B; Romero-Rodriguez, R; Soriano-Navarro, M; Garcia-Verdugo, JM; Alvarez-Buylla, A (2009). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3346259">«Epidermal growth factor induces the progeny of subventricular zone type B cells to migrate and differentiate into oligodendrocytes.»</a>. <i>Stem Cells</i>. <b>27</b> (8): 2032–43. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3346259">3346259</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/19544429">19544429</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1002%2Fstem.119">10.1002/stem.119</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Epidermal+growth+factor+induces+the+progeny+of+subventricular+zone+type+B+cells+to+migrate+and+differentiate+into+oligodendrocytes.&rft.au=Alvarez-Buylla%2C+A&rft.au=Garcia-Verdugo%2C+JM&rft.au=Romero-Rodriguez%2C+R&rft.au=Soriano-Navarro%2C+M&rft.aufirst=B&rft.aulast=Gonzalez-Perez%2C+O&rft.date=2009&rft.genre=article&rft.issue=8&rft.jtitle=Stem+Cells&rft.pages=2032-43&rft.volume=27&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3346259&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3346259&rft_id=info%3Adoi%2F10.1002%2Fstem.119&rft_id=info%3Apmid%2F19544429&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Vallstedt, A; Klos JM; Ericson F (2005). «Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain». <i>Neuron</i>. 1. <b>45</b> (1): 55–67. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/15629702">15629702</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.neuron.2004.12.026">10.1016/j.neuron.2004.12.026</a>. <a href="/wiki/Handle_System" title="Handle System">hdl</a>:<a rel="nofollow" class="external text" href="//hdl.handle.net/10616%2F40454">10616/40454</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Multiple+dorsoventral+origins+of+oligodendrocyte+generation+in+the+spinal+cord+and+hindbrain&rft.au=Ericson+F&rft.au=Klos+JM&rft.aufirst=A&rft.aulast=Vallstedt&rft.date=2005&rft.genre=article&rft.issue=1&rft.jtitle=Neuron&rft.pages=55-67&rft.volume=45&rft_id=info%3Adoi%2F10.1016%2Fj.neuron.2004.12.026&rft_id=info%3Ahdl%2F10616%2F40454&rft_id=info%3Apmid%2F15629702&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Thomas, JL; Spassky N; Perez Villegas EM; Olivier C; Cobos I; Goujet-Zalc C; Martínez S; Zalc B. (2000). «Spatiotemporal development of oligodendrocytes in the embryonic brain». <i>Journal of Neuroscience Research</i>. <b>59</b> (4): 471–476. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/10679785">10679785</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1002%2F%28SICI%291097-4547%2820000215%2959%3A4%3C471%3A%3AAID-JNR1%3E3.0.CO%3B2-3">10.1002/(SICI)1097-4547(20000215)59:4<471::AID-JNR1>3.0.CO;2-3</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Spatiotemporal+development+of+oligodendrocytes+in+the+embryonic+brain&rft.au=Cobos+I&rft.au=Goujet-Zalc+C&rft.au=Mart%C3nez+S&rft.au=Olivier+C&rft.au=Perez+Villegas+EM&rft.au=Spassky+N&rft.au=Zalc+B.&rft.aufirst=JL&rft.aulast=Thomas&rft.date=2000&rft.genre=article&rft.issue=4&rft.jtitle=Journal+of+Neuroscience+Research&rft.pages=471-476&rft.volume=59&rft_id=info%3Adoi%2F10.1002%2F%28SICI%291097-4547%2820000215%2959%3A4%3C471%3A%3AAID-JNR1%3E3.0.CO%3B2-3&rft_id=info%3Apmid%2F10679785&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Richardson, WD; Kessaris, N; Pringle, N (2006). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC6328010">«Oligodendrocyte wars»</a>. <i>Nature Reviews Neuroscience</i>. 1. <b>7</b> (1): 11–18. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC6328010">6328010</a><span style="margin-left:0.1em"><span typeof="mw:File"><span title="Acessível livremente"><img alt="Acessível livremente" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span></span>. <a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/16371946">16371946</a>. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038%2Fnrn1826">10.1038/nrn1826</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Oligodendrocyte+wars&rft.au=Kessaris%2C+N&rft.au=Pringle%2C+N&rft.aufirst=WD&rft.aulast=Richardson&rft.date=2006&rft.genre=article&rft.issue=1&rft.jtitle=Nature+Reviews+Neuroscience&rft.pages=11-18&rft.volume=7&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6328010&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC6328010&rft_id=info%3Adoi%2F10.1038%2Fnrn1826&rft_id=info%3Apmid%2F16371946&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation book">Fancy, Stephen P. J.; Miller, Robert H. (2020). «Chapter 35 - Signaling pathways that regulate glial development and early migration—oligodendrocytes». In: Rubenstein, J.; Rakic, P.; Chen, B.; Kwan, Kenneth Y. (eds.). <i>Patterning and Cell Type Specification in the Developing CNS and PNS (Second Edition)</i>. [S.l.]: Academic Press. pp. 867–890. <a href="/wiki/International_Standard_Book_Number" title="International Standard Book Number">ISBN</a> <a href="/wiki/Especial:Fontes_de_livros/978-0-12-814405-3" title="Especial:Fontes de livros/978-0-12-814405-3">978-0-12-814405-3</a></cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fpt.wikipedia.org%3AOligodendr%C3%B3cito&rft.atitle=Chapter+35+-+Signaling+pathways+that+regulate+glial+development+and+early+migration%94oligodendrocytes&rft.au=Miller%2C+Robert+H.&rft.aufirst=Stephen+P.+J.&rft.aulast=Fancy&rft.btitle=Patterning+and+Cell+Type+Specification+in+the+Developing+CNS+and+PNS+%28Second+Edition%29&rft.date=2020&rft.genre=bookitem&rft.isbn=978-0-12-814405-3&rft.pages=867-890&rft.pub=Academic+Press&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33"> !CS1 manut: Nomes múltiplos: lista de editores (<a href="/wiki/Categoria:!CS1_manut:_Nomes_m%C3%BAltiplos:_lista_de_editores" title="Categoria:!CS1 manut: Nomes múltiplos: lista de editores">link</a>)</span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="Ligações_externas"><span id="Liga.C3.A7.C3.B5es_externas"></span>Ligações externas</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Oligodendr%C3%B3cito&veaction=edit&section=9" title="Editar secção: Ligações externas" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Oligodendr%C3%B3cito&action=edit&section=9" title="Editar código-fonte da secção: Ligações externas"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="http://www.afh.bio.br/nervoso/nervoso2.asp#neuroglia">Anatomia & Fisiologia Humanas</a></li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20050313073254/http://www.fcm.unicamp.br/departamentos/anatomia/taneutecnervnl.html">Anatomia Unicamp</a></li></ul> <div role="navigation" class="navbox" aria-labelledby="Histologia:_Tecido_nervoso" style="padding:3px"><table class="nowraplinks collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div class="plainlinks hlist navbar mini"><ul><li class="nv-ver"><a href="/wiki/Predefini%C3%A7%C3%A3o:Tecido_nervoso" title="Predefinição:Tecido nervoso"><abbr title="Ver esta predefinição" style=";;background:none transparent;border:none;-moz-box-shadow:none;-webkit-box-shadow:none;box-shadow:none; padding:0;">v</abbr></a></li><li class="nv-discutir"><a href="/wiki/Predefini%C3%A7%C3%A3o_Discuss%C3%A3o:Tecido_nervoso" title="Predefinição Discussão:Tecido nervoso"><abbr title="Discutir esta predefinição" style=";;background:none 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style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Soma_(neurologia)" title="Soma (neurologia)">soma</a>, <a href="/wiki/Ax%C3%B4nio" class="mw-redirect" title="Axônio">axônio</a> (<a href="/w/index.php?title=Axon_hillock&action=edit&redlink=1" class="new" title="Axon hillock (página não existe)">axon hillock</a>, <a href="/wiki/Axoplasma" title="Axoplasma">axoplasma</a>, <a href="/w/index.php?title=Axolema&action=edit&redlink=1" class="new" title="Axolema (página não existe)">axolema</a>, <a href="/wiki/Neurofilamento" title="Neurofilamento">Neurofilamento</a>), <a href="/wiki/Dendrito" title="Dendrito">dendrito</a> (<a href="/wiki/Corp%C3%BAsculo_de_Nissl" title="Corpúsculo de Nissl">corpúsculo de Nissl</a>, <a href="/w/index.php?title=Dendrito_espinhal&action=edit&redlink=1" class="new" title="Dendrito espinhal (página não existe)">dendrito espinhal</a>, <a href="/w/index.php?title=Dendrito_apical&action=edit&redlink=1" class="new" title="Dendrito apical (página não existe)">dendrito apical</a>, <a href="/w/index.php?title=Dendrito_basal&action=edit&redlink=1" class="new" title="Dendrito basal (página não existe)">dendrito basal</a>)<br /><i>tipos</i> (<a href="/w/index.php?title=Bipolar_cell&action=edit&redlink=1" class="new" title="Bipolar cell (página não existe)">bipolar</a>, <a href="/w/index.php?title=Pseudounipolar_cells&action=edit&redlink=1" class="new" title="Pseudounipolar cells (página não existe)">pseudounipolar</a>, <a href="/wiki/Neur%C3%B4nio_multipolar" title="Neurônio multipolar">multipolar</a>, <a href="/wiki/C%C3%A9lula_piramidal" title="Célula piramidal">piramidal</a>, <a href="/wiki/C%C3%A9lula_de_Purkinje" title="Célula de Purkinje">célula de Purkinje</a>, <a href="/w/index.php?title=Granule_cell&action=edit&redlink=1" class="new" title="Granule cell (página não existe)">célula granular</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/w/index.php?title=Nervo_aferente&action=edit&redlink=1" class="new" title="Nervo aferente (página não existe)">nervo aferente</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=General_somatic_afferent_fibers&action=edit&redlink=1" class="new" title="General somatic afferent fibers (página não existe)">GSA</a>, <a href="/w/index.php?title=General_visceral_afferent_fibers&action=edit&redlink=1" class="new" title="General visceral afferent fibers (página não existe)">GVA</a>, <a href="/w/index.php?title=Special_somatic_afferent&action=edit&redlink=1" class="new" title="Special somatic afferent (página não existe)">SSA</a>, <a href="/w/index.php?title=Special_visceral_afferent&action=edit&redlink=1" class="new" title="Special visceral afferent (página não existe)">SVA</a>, fibras (<a href="/wiki/Fibra_sensorial_Ia" title="Fibra sensorial Ia">Ia</a>, <a href="/wiki/%C3%93rg%C3%A3o_tendinoso_de_Golgi" title="Órgão tendinoso de Golgi">Ib ou Golgi</a>, <a href="/wiki/Fibra_sensorial_tipo_II" title="Fibra sensorial tipo II">II</a>, <a href="/w/index.php?title=Fibra_sensorial_III&action=edit&redlink=1" class="new" title="Fibra sensorial III (página não existe)">III</a>, <a href="/w/index.php?title=Fibra_sensorial_IV&action=edit&redlink=1" class="new" title="Fibra sensorial IV (página não existe)">IV</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Nervo_motor" title="Nervo motor">nervo motor</a>/<a href="/wiki/Neur%C3%B4nio_motor" title="Neurônio motor">neurônio motor</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=General_somatic_efferent_fibers&action=edit&redlink=1" class="new" title="General somatic efferent fibers (página não existe)">GSE</a>, <a href="/w/index.php?title=General_visceral_efferent_fibers&action=edit&redlink=1" class="new" title="General visceral efferent fibers (página não existe)">GVE</a>, <a href="/w/index.php?title=Special_visceral_efferent&action=edit&redlink=1" class="new" title="Special visceral efferent (página não existe)">SVE</a>, <a href="/wiki/Neur%C3%B4nio_motor" title="Neurônio motor">neurônio motor</a> superior, <a href="/wiki/Neur%C3%B4nio_motor" title="Neurônio motor">neurônio motor</a> inferior (alfa, beta e gama)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Sinapse_qu%C3%ADmica" class="mw-redirect" title="Sinapse química">sinapses</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=Neur%C3%B3pila&action=edit&redlink=1" class="new" title="Neurópila (página não existe)">neurópila</a>, <a href="/wiki/Ves%C3%ADcula_sin%C3%A1ptica" title="Vesícula sináptica">vesícula sináptica</a>, <a href="/wiki/Jun%C3%A7%C3%A3o_neuromuscular" title="Junção neuromuscular">junção neuromuscular</a>, <a href="/w/index.php?title=Sinapse_el%C3%A9trica&action=edit&redlink=1" class="new" title="Sinapse elétrica (página não existe)">sinapse elétrica</a> - <a href="/wiki/Interneur%C3%B4nio" title="Interneurônio">Interneurônio</a> (<a href="/w/index.php?title=Interneur%C3%B4nio_inibit%C3%B3rio_Ia&action=edit&redlink=1" class="new" title="Interneurônio inibitório Ia (página não existe)">inibitório Ia</a>, <a href="/w/index.php?title=Interneur%C3%B4nio_inibit%C3%B3rio_Ib&action=edit&redlink=1" class="new" title="Interneurônio inibitório Ib (página não existe)">inibitório Ib</a>, <a href="/wiki/C%C3%A9lula_de_Renshaw" title="Célula de Renshaw">célula de Renshaw</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Receptor_sensorial" title="Receptor sensorial">receptores sensoriais</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Termina%C3%A7%C3%A3o_livre" title="Terminação livre">Terminação nervosa livre</a>, <a href="/wiki/Corp%C3%BAsculo_de_Meissner" title="Corpúsculo de Meissner">corpúsculo de Meissner</a>, <a href="/wiki/Disco_de_Merkel" title="Disco de Merkel">disco de Merkel</a>, <a href="/wiki/Fuso_muscular" title="Fuso muscular">fuso muscular</a>, <a href="/wiki/Corp%C3%BAsculo_de_Pacini" title="Corpúsculo de Pacini">corpúsculo de Pacini</a>, <a href="/wiki/Corp%C3%BAsculo_de_Ruffini" title="Corpúsculo de Ruffini">corpúsculo de Ruffini</a>, <a href="/wiki/Neur%C3%B4nios_olfat%C3%B3rios" class="mw-redirect" title="Neurônios olfatórios">beurônio olfativo</a>, <a href="/wiki/Fotorreceptor" title="Fotorreceptor">fotorreceptor</a>, <a href="/w/index.php?title=Receptor_do_fol%C3%ADculo_piloso&action=edit&redlink=1" class="new" title="Receptor do folículo piloso (página não existe)">receptor do folículo piloso</a>, <a href="/wiki/Papila_gustativa" title="Papila gustativa">papila gustativa</a>, <a href="/wiki/%C3%93rg%C3%A3o_tendinoso_de_Golgi" title="Órgão tendinoso de Golgi">órgão tendinoso de Golgi</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/C%C3%A9lula_glial" class="mw-redirect" title="Célula glial">células da glia</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Astr%C3%B3cito" title="Astrócito">astrócito</a>, <a class="mw-selflink selflink">oligodendrócito</a>, <a href="/wiki/Ep%C3%AAndima" title="Epêndima">células ependimárias</a>, <a href="/wiki/Micr%C3%B3glia" title="Micróglia">micróglia</a>, <a href="/w/index.php?title=Glia_radial&action=edit&redlink=1" class="new" title="Glia radial (página não existe)">glia radial</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Mielina" class="mw-redirect" title="Mielina">mielinação</a> (<a href="/wiki/Subst%C3%A2ncia_branca" title="Substância branca">substância branca</a>)</th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/C%C3%A9lula_de_Schwann" title="Célula de Schwann">célula de Schwann</a>, <a class="mw-selflink selflink">oligodendrócito</a>, <a href="/wiki/N%C3%B3dulo_de_Ranvier" title="Nódulo de Ranvier">nódulo de Ranvier</a>, <a href="/w/index.php?title=Internodal_segment&action=edit&redlink=1" class="new" title="Internodal segment (página não existe)">internode</a>, <a href="/w/index.php?title=Incisura_de_Schmidt-Lantermann&action=edit&redlink=1" class="new" title="Incisura de Schmidt-Lantermann (página não existe)">incisura de Schmidt-Lantermann</a>, <a href="/wiki/Neurilema" title="Neurilema">neurolema</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Tecidos_conjuntivos" class="mw-redirect" title="Tecidos conjuntivos">relacionados aos tecidos conjuntivos</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Epineuro" title="Epineuro">epineuro</a>, <a href="/wiki/Perineuro" title="Perineuro">perineuro</a>, <a href="/w/index.php?title=Endoneuro&action=edit&redlink=1" class="new" title="Endoneuro (página não existe)">endoneuro</a>, <a href="/w/index.php?title=Fasc%C3%ADculo_nervoso&action=edit&redlink=1" class="new" title="Fascículo nervoso (página não existe)">fascículo nervoso</a>, <a href="/wiki/Meninges" class="mw-redirect" title="Meninges">meninges</a></div></td></tr></tbody></table></div> <div role="navigation" class="navbox" aria-labelledby="Sistema_nervoso" style="padding:3px"><table class="nowraplinks collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div class="plainlinks hlist navbar mini"><ul><li class="nv-ver"><a href="/wiki/Predefini%C3%A7%C3%A3o:Sistema_nervoso" title="Predefinição:Sistema nervoso"><abbr title="Ver esta predefinição" style=";;background:none transparent;border:none;-moz-box-shadow:none;-webkit-box-shadow:none;box-shadow:none; padding:0;">v</abbr></a></li><li class="nv-discutir"><a href="/w/index.php?title=Predefini%C3%A7%C3%A3o_Discuss%C3%A3o:Sistema_nervoso&action=edit&redlink=1" class="new" title="Predefinição Discussão:Sistema nervoso (página não existe)"><abbr title="Discutir esta predefinição" style=";;background:none transparent;border:none;-moz-box-shadow:none;-webkit-box-shadow:none;box-shadow:none; padding:0;">d</abbr></a></li><li class="nv-editar"><a class="external text" href="https://pt.wikipedia.org/w/index.php?title=Predefini%C3%A7%C3%A3o:Sistema_nervoso&action=edit"><abbr title="Editar esta predefinição" style=";;background:none transparent;border:none;-moz-box-shadow:none;-webkit-box-shadow:none;box-shadow:none; padding:0;">e</abbr></a></li></ul></div><div id="Sistema_nervoso" style="font-size:114%;margin:0 4em"><a href="/wiki/Sistema_nervoso" title="Sistema nervoso">Sistema nervoso</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Sistema_nervoso_central" title="Sistema nervoso central">Sistema nervoso central</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Enc%C3%A9falo" title="Encéfalo">Encéfalo</a> (<a href="/wiki/C%C3%B3rtex_cerebral" title="Córtex cerebral">córtex cerebral</a>, <a href="/wiki/Ponte_(sistema_nervoso)" title="Ponte (sistema nervoso)">ponte</a>, <a href="/wiki/Hipot%C3%A1lamo" title="Hipotálamo">hipotálamo</a>, <a href="/wiki/T%C3%A1lamo_(anatomia)" title="Tálamo (anatomia)">tálamo</a>, <a href="/wiki/Bulbo_raquidiano" title="Bulbo raquidiano">bulbo</a>, <a href="/wiki/Cerebelo" title="Cerebelo">cerebelo</a>), <a href="/wiki/Medula_espinhal" title="Medula espinhal">medula espinhal</a>.</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Sistema_nervoso_perif%C3%A9rico" title="Sistema nervoso periférico">Sistema nervoso periférico</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Nervos_cranianos" class="mw-redirect" title="Nervos cranianos">Nervos cranianos</a>, <a href="/wiki/Nervo_espinhal" title="Nervo espinhal">nervos espinhais</a>, <a href="/wiki/Plexo_nervoso" title="Plexo nervoso">plexo nervoso</a>.</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Neur%C3%B4nio" class="mw-redirect" title="Neurônio">Neurônios</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Peric%C3%A1rio" class="mw-redirect" title="Pericário">Pericário</a>, <a href="/wiki/Dendritos" class="mw-redirect" title="Dendritos">dendritos</a>, <a href="/wiki/Ax%C3%B4nio" class="mw-redirect" title="Axônio">axônio</a>.</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Neur%C3%B3glia" title="Neuróglia">Células da Glia</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a class="mw-selflink selflink">Oligodendrócito</a>/<a href="/wiki/C%C3%A9lula_de_Schwann" title="Célula de Schwann">célula de Schwann</a>, <a href="/wiki/Astr%C3%B3cito" title="Astrócito">astrócitos</a>, <a href="/wiki/Ependim%C3%B3cito" title="Ependimócito">ependimócito</a>, <a href="/wiki/Micr%C3%B3glia" title="Micróglia">micróglia</a>.</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Meninges" class="mw-redirect" title="Meninges">Meninges</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Dura-m%C3%A1ter" title="Dura-máter">Dura-máter</a>, <a href="/wiki/Aracnoide" title="Aracnoide">aracnoide</a>, <a href="/wiki/Pia-m%C3%A1ter" title="Pia-máter">pia-máter</a>.</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Sistema_nervoso_aut%C3%B4nomo" title="Sistema nervoso autônomo">Sistema nervoso autônomo</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Sistema_nervoso_simp%C3%A1tico" title="Sistema nervoso simpático">Sistema nervoso simpático</a>, <a href="/wiki/Sistema_nervoso_parassimp%C3%A1tico" title="Sistema nervoso parassimpático">sistema nervoso parassimpático</a>, <a href="/wiki/Sistema_nervoso_ent%C3%A9rico" title="Sistema nervoso entérico">sistema nervoso entérico</a>.</div></td></tr></tbody></table></div> <div role="navigation" class="navbox" aria-labelledby="Tipos_de_células_humanas" style="padding:3px"><table class="nowraplinks collapsible collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div class="plainlinks hlist navbar mini"><ul><li class="nv-ver"><a href="/wiki/Predefini%C3%A7%C3%A3o:Tipos_de_c%C3%A9lulas_humanas" title="Predefinição:Tipos de células humanas"><abbr title="Ver esta predefinição" style=";;background:none transparent;border:none;-moz-box-shadow:none;-webkit-box-shadow:none;box-shadow:none; padding:0;">v</abbr></a></li><li class="nv-discutir"><a href="/wiki/Predefini%C3%A7%C3%A3o_Discuss%C3%A3o:Tipos_de_c%C3%A9lulas_humanas" title="Predefinição Discussão:Tipos de células humanas"><abbr title="Discutir esta predefinição" style=";;background:none transparent;border:none;-moz-box-shadow:none;-webkit-box-shadow:none;box-shadow:none; padding:0;">d</abbr></a></li><li class="nv-editar"><a class="external text" href="https://pt.wikipedia.org/w/index.php?title=Predefini%C3%A7%C3%A3o:Tipos_de_c%C3%A9lulas_humanas&action=edit"><abbr title="Editar esta predefinição" style=";;background:none transparent;border:none;-moz-box-shadow:none;-webkit-box-shadow:none;box-shadow:none; padding:0;">e</abbr></a></li></ul></div><div id="Tipos_de_células_humanas" style="font-size:114%;margin:0 4em">Tipos de <a href="/wiki/C%C3%A9lula" title="Célula">células</a> humanas</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: Linen;background-color:#FFC0CB;"><a href="/wiki/Sangue" title="Sangue">Sangue</a> / <a href="/wiki/Imunidade" title="Imunidade">imunidade</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><i><b><a href="/w/index.php?title=Linhagem_linf%C3%B3ide&action=edit&redlink=1" class="new" title="Linhagem linfóide (página não existe)">Linhagem linfóide</a>:</b></i> <a href="/wiki/Linf%C3%B3cito_B" title="Linfócito B">Linfócito B</a> <b>·</b>  <a href="/wiki/Linf%C3%B3cito_T" title="Linfócito T">Linfócito T</a> (<a href="/wiki/Linf%C3%B3cito_T_citot%C3%B3xico" title="Linfócito T citotóxico">Linfócito T citotóxico</a>, <a href="/wiki/C%C3%A9lula_T_natural_killer" class="mw-redirect" title="Célula T natural killer">Célula T natural killer</a>, <a href="/w/index.php?title=C%C3%A9lula_T_reguladora&action=edit&redlink=1" class="new" title="Célula T reguladora (página não existe)">Célula T reguladora</a>, <a href="/wiki/Linf%C3%B3cito_T_auxiliar" title="Linfócito T auxiliar">Linfócito T auxiliar</a>) <b>·</b>  <a href="/wiki/C%C3%A9lula_NK" class="mw-redirect" title="Célula NK">Célula NK</a><br /> <i><b><a href="/w/index.php?title=Linhagem_miel%C3%B3ide&action=edit&redlink=1" class="new" title="Linhagem mielóide (página não existe)">Linhagem mielóide</a>:</b></i> <a href="/wiki/Granul%C3%B3cito" title="Granulócito">Granulócito</a> (<a href="/wiki/Granul%C3%B3cito_bas%C3%B3filo" title="Granulócito basófilo">Granulócito basófilo</a>, <a href="/wiki/Granul%C3%B3cito_eosin%C3%B3filo" title="Granulócito eosinófilo">Granulócito eosinófilo</a>, <a href="/wiki/Granul%C3%B3cito_neutr%C3%B3filo" title="Granulócito neutrófilo">Granulócito neutrófilo</a>/<a href="/w/index.php?title=Neutr%C3%B3filo_hipersegmentado&action=edit&redlink=1" class="new" title="Neutrófilo hipersegmentado (página não existe)">Neutrófilo hipersegmentado</a>) <b>·</b>  <a href="/wiki/Mon%C3%B3cito" title="Monócito">Monócito</a> / <a href="/wiki/Macr%C3%B3fago" title="Macrófago">Macrófago</a> <b>·</b>  <a href="/wiki/Reticul%C3%B3cito" title="Reticulócito">Reticulócito</a> / <a href="/wiki/Hem%C3%A1cia" title="Hemácia">Hemácia</a> <b>·</b>  <a href="/wiki/Mast%C3%B3cito" title="Mastócito">Mastócito</a> <b>·</b>  <a href="/wiki/Megacari%C3%B3cito" title="Megacariócito">Megacariócito</a> / <a href="/wiki/Tromb%C3%B3cito" class="mw-redirect" title="Trombócito">Trombócito</a> <b>·</b>  <a href="/wiki/C%C3%A9lula_dendr%C3%ADtica" title="Célula dendrítica">Célula dendrítica</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: Linen;background:#efefef;"><a href="/wiki/Sistema_end%C3%B3crino" title="Sistema endócrino">Sistema endócrino</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><i><a href="/wiki/Tiroide" title="Tiroide">tiroide</a></i> (<a href="/wiki/C%C3%A9lula_epitelial_da_tiroide" title="Célula epitelial da tiroide">Célula epitelial da tiroide</a>, <a href="/wiki/C%C3%A9lula_parafolicular" title="Célula parafolicular">Célula parafolicular</a>)  <b>·</b>  <i><a href="/wiki/Gl%C3%A2ndula_paratiroide" title="Glândula paratiroide">paratiroide</a></i> (<a href="/wiki/C%C3%A9lula_principal_da_paratiroide" title="Célula principal da paratiroide">Célula principal da paratiroide</a>, <a href="/w/index.php?title=C%C3%A9lula_Ox%C3%ADfilas_paratire%C3%B3ide&action=edit&redlink=1" class="new" title="Célula Oxífilas paratireóide (página não existe)">célula oxífilas</a>)  <b>·</b>  <i><a href="/wiki/Gl%C3%A2ndula_suprarrenal" title="Glândula suprarrenal">adrenal</a></i> (<a href="/wiki/C%C3%A9lula_cromafim" title="Célula cromafim">Célula cromafim</a>) <b>·</b>  <i><a href="/wiki/Gl%C3%A2ndula_pineal" title="Glândula pineal">pineal</a></i> (<a href="/wiki/Pineal%C3%B3cito" title="Pinealócito">Pinealócito</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: Linen;background:LightYellow;"><a href="/wiki/Sistema_nervoso" title="Sistema nervoso">Sistema nervoso</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><i><a href="/wiki/C%C3%A9lula_da_glia" class="mw-redirect" title="Célula da glia">células da glia</a>:</i> <a href="/w/index.php?title=Glioblasto&action=edit&redlink=1" class="new" title="Glioblasto (página não existe)">Glioblasto</a> (<a href="/wiki/Astr%C3%B3cito" title="Astrócito">Astrócito</a>, <a class="mw-selflink selflink">Oligodendrócito</a>) <b>·</b>  <a href="/wiki/Micr%C3%B3glia" title="Micróglia">Micróglia</a> <p><a href="/w/index.php?title=Magnocellular_neurosecretory_cell&action=edit&redlink=1" class="new" title="Magnocellular neurosecretory cell (página não existe)">Magnocellular neurosecretory cell</a>  <b>·</b>  <a href="/w/index.php?title=Stellate_cell&action=edit&redlink=1" class="new" title="Stellate cell (página não existe)">Stellate cell</a> <b>·</b>  <a href="/w/index.php?title=Boettcher_cell&action=edit&redlink=1" class="new" title="Boettcher cell (página não existe)">Boettcher cell</a> </p> <i><a href="/wiki/Hip%C3%B3fise" title="Hipófise">hipófise</a></i> (<a href="/wiki/Gonadotrofo" title="Gonadotrofo">Gonadotrofo</a>, <a href="/w/index.php?title=Corticotrofo&action=edit&redlink=1" class="new" title="Corticotrofo (página não existe)">Corticotrofo</a>, <a href="/w/index.php?title=Tirotrofo&action=edit&redlink=1" class="new" title="Tirotrofo (página não existe)">Tirotrofo</a>, <a href="/wiki/Somatotrofo" title="Somatotrofo">Somatotrofo</a>, <a href="/wiki/Lactotrofo" title="Lactotrofo">Lactotrofo</a> )</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: Linen;background:MistyRose;"><a href="/wiki/Sistema_respirat%C3%B3rio" title="Sistema respiratório">Sistema respiratório</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Pneum%C3%B3cito" title="Pneumócito">Pneumócito</a> (<a href="/wiki/Pneum%C3%B3cito_tipo_I" title="Pneumócito tipo I">Pneumócito tipo I</a>, <a href="/wiki/Pneum%C3%B3cito_tipo_II" title="Pneumócito tipo II">Pneumócito tipo II</a>) <b>·</b>  <a href="/wiki/C%C3%A9lulas_de_Clara" class="mw-redirect" title="Células de Clara">Células de Clara</a> <b>·</b>  <a href="/wiki/C%C3%A9lula_de_Goblet" class="mw-redirect" title="Célula de Goblet">Célula de Goblet</a> <b>·</b>  <a href="/w/index.php?title=Macr%C3%B3fago_alveolar&action=edit&redlink=1" class="new" title="Macrófago alveolar (página não existe)">Macrófago alveolar</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: Linen;background:MistyRose;"><a href="/wiki/Sistema_circulat%C3%B3rio" title="Sistema circulatório">Sistema circulatório</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=Miocardi%C3%B3cito&action=edit&redlink=1" class="new" title="Miocardiócito (página não existe)">Miocardiócito</a> <b>·</b>  <a href="/wiki/Pericito" title="Pericito">Pericito</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: Linen;background:#fd6;"><a href="/wiki/Sistema_digestivo" class="mw-redirect" title="Sistema digestivo">Sistema digestivo</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><i><a href="/wiki/Est%C3%B4mago" title="Estômago">estômago</a></i> (<a href="/wiki/C%C3%A9lula_principal" title="Célula principal">Célula principal</a>, <a href="/wiki/C%C3%A9lula_parietal" title="Célula parietal">Célula parietal</a>) <b>·</b>  <a href="/wiki/C%C3%A9lula_de_Goblet" class="mw-redirect" title="Célula de Goblet">Célula de Goblet</a> <b>·</b>  <a href="/wiki/C%C3%A9lula_de_Paneth" title="Célula de Paneth">Célula de Paneth</a> <p><a href="/wiki/C%C3%A9lula_G" title="Célula G">Célula G</a> <b>·</b>  <a href="/w/index.php?title=Delta_cell&action=edit&redlink=1" class="new" title="Delta cell (página não existe)">D cells</a> <b>·</b>  <a href="/w/index.php?title=Enterochromaffin-like_cell&action=edit&redlink=1" class="new" title="Enterochromaffin-like cell (página não existe)">ECL cells</a> <b>·</b>  <a href="/w/index.php?title=Cholecystokinin&action=edit&redlink=1" class="new" title="Cholecystokinin (página não existe)">I cells</a>  <b>·</b>  <a href="/w/index.php?title=Gastric_inhibitory_polypeptide&action=edit&redlink=1" class="new" title="Gastric inhibitory polypeptide (página não existe)">K cells</a>  <b>·</b>  <a href="/w/index.php?title=S_cell&action=edit&redlink=1" class="new" title="S cell (página não existe)">S cells</a> </p><p><a href="/wiki/C%C3%A9lula_enteroend%C3%B3crina" title="Célula enteroendócrina">Célula enteroendócrina</a> <b>·</b>  <a href="/wiki/C%C3%A9lula_enterocromafim" title="Célula enterocromafim">Célula enterocromafim</a> <b>·</b>  <a href="/wiki/C%C3%A9lula_APUD" title="Célula APUD">Célula APUD</a> </p> <i><a href="/wiki/F%C3%ADgado" title="Fígado">fígado</a></i> (<a href="/wiki/Hepat%C3%B3cito" title="Hepatócito">Hepatócito</a>, <a href="/wiki/C%C3%A9lula_de_Kupffer" title="Célula de Kupffer">Célula de Kupffer</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: Linen;background:Linen;"><a href="/wiki/Sistema_esquel%C3%A9tico" class="mw-redirect" title="Sistema esquelético">Sistema esquelético</a>/<br /><a href="/wiki/Sistema_tegumentar" title="Sistema tegumentar">Sistema tegumentar</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><i>osso:</i> <a href="/wiki/Osteoblasto" title="Osteoblasto">Osteoblasto</a> <b>·</b>  <a href="/wiki/Oste%C3%B3cito" title="Osteócito">Osteócito</a> <b>·</b>  <a href="/wiki/Osteoclasto" title="Osteoclasto">Osteoclasto</a> <b>·</b>  <i>dente:</i> <a href="/wiki/Ameloblasto" title="Ameloblasto">Ameloblasto</a> <b>·</b>  <a href="/wiki/Cementoblasto" title="Cementoblasto">Cementoblasto</a><br /> <p><i>cartilagem:</i> <a href="/wiki/Condroblasto" title="Condroblasto">Condroblasto</a> <b>·</b>  <a href="/wiki/Condr%C3%B3cito" title="Condrócito">Condrócito</a> <b>·</b>  <i>pele e anexos:</i> <a href="/wiki/Melan%C3%B3cito" title="Melanócito">Melanócito</a> <b>·</b>  <a href="/wiki/Queratin%C3%B3cito" title="Queratinócito">Queratinócito</a><br /> </p> <i>músculo:</i> <a href="/wiki/Fibra_muscular" title="Fibra muscular">Miócito</a> <b>·</b>  <i>outros:</i> <a href="/wiki/Adip%C3%B3cito" title="Adipócito">Adipócito</a> <b>·</b>  <a href="/wiki/Fibroblasto" title="Fibroblasto">Fibroblasto</a> <b>·</b>  <a href="/w/index.php?title=C%C3%A9lula_tend%C3%ADnea&action=edit&redlink=1" class="new" title="Célula tendínea (página não existe)">Célula tendínea</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: Linen;background:#BBEEBB;"><a href="/wiki/Sistema_urin%C3%A1rio" class="mw-redirect" title="Sistema urinário">Sistema urinário</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/Pod%C3%B3cito" title="Podócito">Podócito</a>  <b>·</b>  <a href="/wiki/C%C3%A9lula_justaglomerular" title="Célula justaglomerular">Célula justaglomerular</a>  <b>·</b>  <a href="/w/index.php?title=Intraglomerular_mesangial_cell&action=edit&redlink=1" class="new" title="Intraglomerular mesangial cell (página não existe)">Intraglomerular mesangial cell</a>/<a href="/w/index.php?title=Extraglomerular_mesangial_cell&action=edit&redlink=1" class="new" title="Extraglomerular mesangial cell (página não existe)">Extraglomerular mesangial cell</a>  <b>·</b>  <a href="/w/index.php?title=Kidney_proximal_tubule_brush_border_cell&action=edit&redlink=1" class="new" title="Kidney proximal tubule brush border cell (página não existe)">Kidney proximal tubule brush border cell</a>  <b>·</b>  <a href="/w/index.php?title=C%C3%A9lula_da_m%C3%A1cula_densa&action=edit&redlink=1" class="new" title="Célula da mácula densa (página não existe)">Célula da mácula densa</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: Linen;background:#BBEEBB;"><a href="/wiki/Sistema_reprodutor" class="mw-redirect" title="Sistema reprodutor">Sistema reprodutor</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"><i>homem:</i> <a href="/wiki/Espermatozoide" title="Espermatozoide">Espermatozoide</a> <b>·</b>  <a href="/wiki/C%C3%A9lula_de_Sertoli" title="Célula de Sertoli">Célula de Sertoli</a> <b>·</b>  <a href="/wiki/C%C3%A9lula_de_Leydig" title="Célula de Leydig">Célula de Leydig</a> <b>·</b>  <i>mulher:</i> <a href="/wiki/Ov%C3%B3cito" title="Ovócito">Ovócito</a> <b>·</b>  <a href="/wiki/C%C3%A9lula_da_granulosa" title="Célula da granulosa">Célula da granulosa</a></div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><i>ver também <a href="/w/index.php?title=Anexo:Lista_de_tipos_celulares_no_ser_humano_adulto&action=edit&redlink=1" class="new" title="Anexo:Lista de tipos celulares no ser humano adulto (página não existe)">Anexo:Lista de tipos celulares no ser humano adulto</a></i></div></td></tr></tbody></table></div> <!-- NewPP limit report Parsed by mw‐web.eqiad.main‐565d46677b‐ds5lv Cached time: 20241128121456 Cache expiry: 2592000 Reduced expiry: false Complications: [show‐toc] CPU time usage: 0.553 seconds Real time usage: 0.660 seconds Preprocessor visited node count: 4766/1000000 Post‐expand include size: 142281/2097152 bytes Template argument size: 1986/2097152 bytes Highest expansion depth: 17/100 Expensive parser function count: 2/500 Unstrip recursion depth: 0/20 Unstrip post‐expand size: 52518/5000000 bytes Lua time usage: 0.165/10.000 seconds Lua memory usage: 4339427/52428800 bytes Number of Wikibase entities loaded: 1/400 --> <!-- Transclusion expansion time report (%,ms,calls,template) 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