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Guo</title> <meta name="description" content="Search results for: Ziwei Guo"> <meta name="keywords" content="Ziwei Guo"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Ziwei Guo"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 10</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Ziwei Guo</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Collective Efficacy and Rural Migration in Urban China—Social Determinants on Urbanization, Social Integration and Civic Engagement</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ziwei%20Qi">Ziwei Qi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper focuses on issues on Urbanization, Rural Migration and Neighborhood Collective Efficacy in urban China. The urbanization and migration trend and policies in China will be discussed and the various mechanisms through which social structures affect economic action and the consequent of social disequilibrium due to urbanization will be discussed. The positive and negative propositions on urbanization will also be highlighted. The primary methodologies applied in the paper will be the theoretical application and empirical implication on urbanization in developing countries. Western sociological theories, including theories in urban criminology /sociology including social disorganization, theories of social capital and collective efficacy will be applied and analyzed to test the market society in Chinese economic and cultural setting. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=collective%20efficacy" title="collective efficacy">collective efficacy</a>, <a href="https://publications.waset.org/abstracts/search?q=civic%20engagement" title=" civic engagement"> civic engagement</a>, <a href="https://publications.waset.org/abstracts/search?q=rural%20migration" title=" rural migration"> rural migration</a>, <a href="https://publications.waset.org/abstracts/search?q=urbanization" title=" urbanization"> urbanization</a> </p> <a href="https://publications.waset.org/abstracts/36411/collective-efficacy-and-rural-migration-in-urban-china-social-determinants-on-urbanization-social-integration-and-civic-engagement" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/36411.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">331</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> Analysis of NFC and Biometrics in the Retail Industry</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ziwei%20Xu">Ziwei Xu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The increasing emphasis on mobility has driven the application of innovative communication technologies across various industries. In the retail sector, Near Field Communication (NFC) has emerged as a significant and transformative technology, particularly in the payment and retail supermarket sectors. NFC enables new payment methods, such as electronic wallets, and enhances information management in supermarkets, contributing to the growth of the trade. This report presents a comprehensive analysis of NFC technology, focusing on five key aspects. Firstly, it provides an overview of NFC, including its application methods and development history. Additionally, it incorporates Arthur's work on combinatorial evolution to elucidate the emergence and impact of NFC technology, while acknowledging the limitations of the model in analyzing NFC. The report then summarizes the positive influence of NFC on the retail industry along with its associated constraints. Furthermore, it explores the adoption of NFC from both organizational and individual perspectives, employing the Best Predictors of organizational IT adoption and UTAUT2 models, respectively. Finally, the report discusses the potential future replacement of NFC with biometrics technology, highlighting its advantages over NFC and leveraging Arthur's model to investigate its future development prospects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=innovation" title="innovation">innovation</a>, <a href="https://publications.waset.org/abstracts/search?q=NFC" title=" NFC"> NFC</a>, <a href="https://publications.waset.org/abstracts/search?q=industry" title=" industry"> industry</a>, <a href="https://publications.waset.org/abstracts/search?q=biometrics" title=" biometrics"> biometrics</a> </p> <a href="https://publications.waset.org/abstracts/167485/analysis-of-nfc-and-biometrics-in-the-retail-industry" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/167485.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">75</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Overview of Standard Unit System of Shenzhen Land Spatial Planning and Case Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ziwei%20Huang">Ziwei Huang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The standard unit of Shenzhen land spatial planning has the characteristics of vertical conduction, horizontal evaluation, internal balance and supervision of implementation. It mainly assumes the role of geospatial unit, assists in promoting the complex development of the business in Shenzhen and undertakes the management and transmission of upper and lower levels of planning as well as the Urban management functions such as gap analysis of public facilities, planning evaluation and dynamic monitoring of planning information. Combining with the application examples of the analysis of gaps in public facilities in Longgang District, it can be found that the standard unit of land spatial planning in Shenzhen as a small-scale geographic basic unit, has a stronger urban spatial coupling effect. However, the universality of the application of the system is still lacking and it is necessary to propose more scientific and powerful standard unit delineation standards and planning function evaluation indicators to guide the implementation of the system's popularization and application. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shenzhen%20city" title="Shenzhen city">Shenzhen city</a>, <a href="https://publications.waset.org/abstracts/search?q=land%20spatial%20planning" title=" land spatial planning"> land spatial planning</a>, <a href="https://publications.waset.org/abstracts/search?q=standard%20unit%20system" title=" standard unit system"> standard unit system</a>, <a href="https://publications.waset.org/abstracts/search?q=urban%20delicacy%20management" title=" urban delicacy management"> urban delicacy management</a> </p> <a href="https://publications.waset.org/abstracts/146407/overview-of-standard-unit-system-of-shenzhen-land-spatial-planning-and-case-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/146407.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">128</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> A Preliminary Study of Urban Resident Space Redundancy in the Context of Rapid Urbanization: Based on Urban Research of Hongkou District of Shanghai</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ziwei%20Chen">Ziwei Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Yujiang%20Gao"> Yujiang Gao</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The rapid urbanization has caused the massive physical space in Chinese cities to be in a state of duplication and dislocation through the rapid development, forming many daily spaces that cannot be standardized, typed, and identified, such as illegal construction. This phenomenon is known as urban spatial redundancy and is often excluded from mainstream architectural discussions because of its 'remaining' and 'excessive' derogatory label. In recent years, some practice architects have begun to pay attention to this phenomenon and tried to tap the value behind it. In this context, the author takes the redundancy phenomenon of resident space as the research object and explores the inspiration to the urban architectural renewal and the innovative residential area model, based on the urban survey of redundant living space in Hongkou District of Shanghai. On this basis, it shows that the changes accumulated in the long-term use of the building can be re-applied to the goals before the design, which is an important link and significance of the existence of an architecture. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=rapid%20urbanization" title="rapid urbanization">rapid urbanization</a>, <a href="https://publications.waset.org/abstracts/search?q=living%20space%20redundancy" title=" living space redundancy"> living space redundancy</a>, <a href="https://publications.waset.org/abstracts/search?q=architectural%20renewal" title=" architectural renewal"> architectural renewal</a>, <a href="https://publications.waset.org/abstracts/search?q=residential%20area%20model" title=" residential area model"> residential area model</a> </p> <a href="https://publications.waset.org/abstracts/93404/a-preliminary-study-of-urban-resident-space-redundancy-in-the-context-of-rapid-urbanization-based-on-urban-research-of-hongkou-district-of-shanghai" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/93404.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">135</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Post Occupancy Evaluation of the Green Office Building with Different Air-Conditioning Systems</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ziwei%20Huang">Ziwei Huang</a>, <a href="https://publications.waset.org/abstracts/search?q=Jian%20Ge"> Jian Ge</a>, <a href="https://publications.waset.org/abstracts/search?q=Jie%20Shen"> Jie Shen</a>, <a href="https://publications.waset.org/abstracts/search?q=Jiantao%20Weng"> Jiantao Weng</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Retrofitting of existing buildings plays a critical role to achieve sustainable development. This is being considered as one of the approaches to achieving sustainability in the built environment. In order to evaluate the different air-conditioning systems effectiveness and user satisfaction of the existing building which had transformed into green building effectively and accurately. This article takes the green office building in Zhejiang province, China as an example, analyzing the energy consumption, occupant satisfaction and indoor environment quality (IEQ) from the perspective of the thermal environment. This building is special because it combines ground source heat pump system and Variable Refrigerant Flow (VRF) air-conditioning system. Results showed that the ground source heat pump system(EUIa≈25.6) consumes more energy than VRF(EUIb≈23.8). In terms of a satisfaction survey, the use of the VRF air-conditioning was more satisfactory in temperature. However, the ground source heat pump is more satisfied in air quality. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=post-occupancy%20evaluation" title="post-occupancy evaluation">post-occupancy evaluation</a>, <a href="https://publications.waset.org/abstracts/search?q=green%20office%20building" title=" green office building"> green office building</a>, <a href="https://publications.waset.org/abstracts/search?q=air-conditioning%20systems" title=" air-conditioning systems"> air-conditioning systems</a>, <a href="https://publications.waset.org/abstracts/search?q=ground%20source%20heat%20pump%20system" title=" ground source heat pump system"> ground source heat pump system</a> </p> <a href="https://publications.waset.org/abstracts/88345/post-occupancy-evaluation-of-the-green-office-building-with-different-air-conditioning-systems" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/88345.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">196</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Beyond ‘Mother India’ and ‘New Indian Woman’: Indian Educated Middle-Class Women in Partition Novels</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yan%20Ziwei">Yan Ziwei</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This article attempts to restore the subjectivity of Indian-educated middle-class women during the partition period through three partition novels: Anita Desai’s Clear Light of Day (1980), Amitav Ghosh’s The Shadow Lines (1988), and Vikram Seth’s A Suitable Boy (1993). Despite extensive research on women in partition, there is little focus on the group of educated middle-class women. In mainstream historical and political discourse, these women have consistently been constructed within the official discourse dominated by males. They are either ‘Mother India’, or the ‘new woman’ to meet the requirements of India’s changing political atmosphere. However, by delving into the particular historical context and personal experience of the educated middle-class women in the three novels, the article argues that they continuously subvert the essentialized identities imposed upon them by different versions of official discourse. As the embodiment of Shakti, they are distinct from the archetypes of ‘Mother India’ and the ‘new woman’. Instead, they create their ideal family spaces based on their personal cognition and transcend the homogeneous gender discourse to reflect the fluid and complex nature of female identity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Indian%20educated%20middle-class%20women" title="Indian educated middle-class women">Indian educated middle-class women</a>, <a href="https://publications.waset.org/abstracts/search?q=subjectivity" title=" subjectivity"> subjectivity</a>, <a href="https://publications.waset.org/abstracts/search?q=partition%20novels" title=" partition novels"> partition novels</a>, <a href="https://publications.waset.org/abstracts/search?q=Mother%20India" title=" Mother India"> Mother India</a>, <a href="https://publications.waset.org/abstracts/search?q=new%20woman" title=" new woman"> new woman</a>, <a href="https://publications.waset.org/abstracts/search?q=Shakti" title=" Shakti"> Shakti</a> </p> <a href="https://publications.waset.org/abstracts/188833/beyond-mother-india-and-new-indian-woman-indian-educated-middle-class-women-in-partition-novels" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/188833.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">43</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Research on the Strategy of Old City Reconstruction under Market Orientation: Taking Mutoulong Community in Shenzhen as an Example</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ziwei%20Huang">Ziwei Huang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In order to promote Inventory development in Shenzhen, the market-oriented real estate development mode has occupied a dominant position in the urban renewal activities of Shenzhen. This research is based on the theory of role relationship and urban regime, taking the Mutoulong community as the research object. Carries on the case depth analysis found that: Under the situation of absence and dislocation of the government's role, land property rights disputes and lack of communication platforms is the main reason for the problems of nail households and market failures, and the long-term delay in the progress of old city reconstruction. Through the analysis of the cause of the transformation problem and the upper planning and interest coordination mechanism, the optimization strategy of the old city transformation is finally proposed as follows: the establishment of interest coordination platform, the risk assessment of the government's intervention in the preliminary construction of the land, the adaptive construction of laws and regulations, and the re-examination of the interest relationship between the government and the market. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shenzhen%20city" title="Shenzhen city">Shenzhen city</a>, <a href="https://publications.waset.org/abstracts/search?q=Mutoulong%20community" title=" Mutoulong community"> Mutoulong community</a>, <a href="https://publications.waset.org/abstracts/search?q=urban%20regeneration" title=" urban regeneration"> urban regeneration</a>, <a href="https://publications.waset.org/abstracts/search?q=urban%20regime%20theory" title=" urban regime theory"> urban regime theory</a>, <a href="https://publications.waset.org/abstracts/search?q=role%20relationship%20theory" title=" role relationship theory"> role relationship theory</a> </p> <a href="https://publications.waset.org/abstracts/146412/research-on-the-strategy-of-old-city-reconstruction-under-market-orientation-taking-mutoulong-community-in-shenzhen-as-an-example" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/146412.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">96</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Electrospun Membrane doped with Gold Nanorods for Surface-Enhanced Raman Sepctroscopy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ziwei%20Wang">Ziwei Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrea%20Lucotti"> Andrea Lucotti</a>, <a href="https://publications.waset.org/abstracts/search?q=Luigi%20Brambilla"> Luigi Brambilla</a>, <a href="https://publications.waset.org/abstracts/search?q=Matteo%20Tommasini"> Matteo Tommasini</a>, <a href="https://publications.waset.org/abstracts/search?q=Chiara%20Bertarelli"> Chiara Bertarelli</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Surface-enhanced Raman Spectroscopy (SERS) is a highly sensitive detection that provides abundant information on low concentration analytes from various researching areas. Based on localized surface plasmon resonance, metal nanostructures including gold, silver and copper have been investigated as SERS substrate during recent decades. There has been increasing more attention of exploring good performance, homogenous, repeatable SERS substrates. Here, we show that electrospinning, which is an inexpensive technique to fabricate large-scale, self-standing and repeatable membranes, can be effectively used for producing SERS substrates. Nanoparticles and nanorods are added to the feed electrospinning solution to collect functionalized polymer fibrous mats. We report stable electrospun membranes as SERS substrate using gold nanorods (AuNRs) and poly(vinyl alcohol). Particularly, a post-processing crosslinking step using glutaraldehyde under acetone environment was carried out to the electrospun membrane. It allows for using the membrane in any liquid environment, including water, which is of interest both for sensing of contaminant in wastewater, as well as for biosensing. This crosslinked AuNRs/PVA membrane has demonstrated excellent performance as SERS substrate for low concentration 10-6 M Rhodamine 6G (Rh6G) aqueous solution. This post-processing for fabricating SERS substrate is the first time reported and proved through Raman imaging of excellent stability and outstanding performance. Finally, SERS tests have been applied to several analytes, and the application of AuNRs/PVA membrane is broadened by removing the detected analyte by rinsing. Therefore, this crosslinked AuNRs/PVA membrane is re-usable. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=SERS%20spectroscopy" title="SERS spectroscopy">SERS spectroscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=electrospinning" title=" electrospinning"> electrospinning</a>, <a href="https://publications.waset.org/abstracts/search?q=crosslinking" title=" crosslinking"> crosslinking</a>, <a href="https://publications.waset.org/abstracts/search?q=composite%20materials" title=" composite materials"> composite materials</a> </p> <a href="https://publications.waset.org/abstracts/149036/electrospun-membrane-doped-with-gold-nanorods-for-surface-enhanced-raman-sepctroscopy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/149036.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">140</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Analysing Modern City Heritage through Modernization Transformation: A Case of Wuhan, China</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ziwei%20Guo">Ziwei Guo</a>, <a href="https://publications.waset.org/abstracts/search?q=Liangping%20Hong"> Liangping Hong</a>, <a href="https://publications.waset.org/abstracts/search?q=Zhiguo%20Ye"> Zhiguo Ye</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The exogenous modernization process in China and other late-coming countries, is not resulted from a gradual growth of their own modernity features, but a conscious response to external challenges. Under this context, it had been equally important for Chinese cities to make themselves ‘Chinese’ as well as ‘modern’. Wuhan was the first opened inland treaty port in late Qing Dynasty. In the following one hundred years, Wuhan transferred from a feudal town to a modern industrial city. It is a good example to illustrate the urban construction and cultural heritage through the process and impact of social transformation. An overall perspective on transformation will contribute to develop the city`s uniqueness and enhance its inclusive development. The study chooses the history of Wuhan from 1861 to 1957 as the study period. The whole transformation process will be divided into four typical periods based on key historical events, and the paper analyzes the changes on urban structure and constructions activities in each period. Then, a lot of examples are used to compare the features of Wuhan modern city heritage in the four periods. In this way, three characteristics of Wuhan modern city heritage are summarized. The paper finds that globalization and localization worked together to shape the urban physical space environment. For Wuhan, social transformation has a profound and comprehensive impact on urban construction, which can be analyzed in the aspects of main construction, architecture style, location and actors. Moreover, the three towns of Wuhan have a disparate cityscape that is reflected by the varied heritages and architecture features over different transformation periods. Lastly, the protection regulations and conservation planning of heritage in Wuhan are discussed, and suggestions about the conservation of Wuhan modern heritage are tried to be drawn. The implications of the study are providing a new perspective on modern city heritage for cities like Wuhan, and the future local planning system and heritage conservation policies can take into consideration the ‘Modern Cultural Transformation Route’ in this paper. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=modern%20city%20heritage" title="modern city heritage">modern city heritage</a>, <a href="https://publications.waset.org/abstracts/search?q=transformation" title=" transformation"> transformation</a>, <a href="https://publications.waset.org/abstracts/search?q=identity" title=" identity"> identity</a>, <a href="https://publications.waset.org/abstracts/search?q=Wuhan" title=" Wuhan"> Wuhan</a> </p> <a href="https://publications.waset.org/abstracts/79543/analysing-modern-city-heritage-through-modernization-transformation-a-case-of-wuhan-china" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79543.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">131</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Liver Regeneration of Small in situ Injury</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ziwei%20Song">Ziwei Song</a>, <a href="https://publications.waset.org/abstracts/search?q=Junjun%20Fan"> Junjun Fan</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeremy%20Teo"> Jeremy Teo</a>, <a href="https://publications.waset.org/abstracts/search?q=Yang%20Yu"> Yang Yu</a>, <a href="https://publications.waset.org/abstracts/search?q=Yukun%20Ma"> Yukun Ma</a>, <a href="https://publications.waset.org/abstracts/search?q=Jie%20Yan"> Jie Yan</a>, <a href="https://publications.waset.org/abstracts/search?q=Shupei%20Mo"> Shupei Mo</a>, <a href="https://publications.waset.org/abstracts/search?q=Lisa%20Tucker-Kellogg"> Lisa Tucker-Kellogg</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20So"> Peter So</a>, <a href="https://publications.waset.org/abstracts/search?q=Hanry%20Yu"> Hanry Yu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Liver is the center of detoxification and exposed to toxic metabolites all the time. It is highly regenerative after injury, with the ability to restore even after 70% partial hepatectomy. Most of the previous studies were using hepatectomy as injury models for liver regeneration study. There is limited understanding of small-scale liver injury, which can be caused by either low dose drug consumption or hepatocyte routine metabolism. Although these small in situ injuries do not cause immediate symptoms, repeated injuries will lead to aberrant wound healing in liver. Therefore, the cellular dynamics during liver regeneration is critical for our understanding of liver regeneration mechanism. We aim to study the liver regeneration of small-scale in situ liver injury in transgenic mice labeling actin (Lifeact-GFP). Previous studies have been using sample sections and biopsies of liver, which lack real-time information. In order to trace every individual hepatocyte during the regeneration process, we have developed and optimized an intravital imaging system that allows in vivo imaging of mouse liver for consecutive 5 days, allowing real-time cellular tracking and quantification of hepatocytes. We used femtosecond-laser ablation to make controlled and repeatable liver injury model, which mimics the real-life small in situ liver injury. This injury model is the first case of its kind for in vivo study on liver. We found that small-scale in situ liver injury is repaired by the coordination of hypertrophy and migration of hepatocytes. Hypertrophy is only transient at initial phase, while migration is the main driving force to complete the regeneration process. From cellular aspect, Akt/mTOR pathway is activated immediately after injury, which leads to transient hepatocyte hypertrophy. From mechano-sensing aspect, the actin cable, formed at apical surface of wound proximal hepatocytes, provides mechanical tension for hepatocyte migration. This study provides important information on both chemical and mechanical signals that promote liver regeneration of small in situ injury. We conclude that hypertrophy and migration play a dominant role at different stages of liver regeneration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hepatocyte" title="hepatocyte">hepatocyte</a>, <a href="https://publications.waset.org/abstracts/search?q=hypertrophy" title=" hypertrophy"> hypertrophy</a>, <a href="https://publications.waset.org/abstracts/search?q=intravital%20imaging" title=" intravital imaging"> intravital imaging</a>, <a href="https://publications.waset.org/abstracts/search?q=liver%20regeneration" title=" liver regeneration"> liver regeneration</a>, <a href="https://publications.waset.org/abstracts/search?q=migration" title=" migration"> migration</a> </p> <a href="https://publications.waset.org/abstracts/77939/liver-regeneration-of-small-in-situ-injury" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/77939.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">205</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); 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