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id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Početak</div> </a> </li> <li id="toc-Struktura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Struktura"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Struktura</span> </div> </a> <button aria-controls="toc-Struktura-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Uključi/isključi podsekciju Struktura</span> </button> <ul id="toc-Struktura-sublist" class="vector-toc-list"> <li id="toc-Mikroanatomija" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Mikroanatomija"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.1</span> <span>Mikroanatomija</span> </div> </a> <ul id="toc-Mikroanatomija-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Opskrba_krvlju_i_nervima" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Opskrba_krvlju_i_nervima"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.2</span> <span>Opskrba krvlju i nervima</span> </div> </a> <ul id="toc-Opskrba_krvlju_i_nervima-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Varijacija" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Varijacija"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.3</span> <span>Varijacija</span> </div> </a> <ul id="toc-Varijacija-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Razvoj" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Razvoj"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Razvoj</span> </div> </a> <button aria-controls="toc-Razvoj-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Uključi/isključi podsekciju Razvoj</span> </button> <ul id="toc-Razvoj-sublist" class="vector-toc-list"> <li id="toc-Involucija" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Involucija"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.1</span> <span>Involucija</span> </div> </a> <ul id="toc-Involucija-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Funkcija" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Funkcija"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Funkcija</span> </div> </a> <button aria-controls="toc-Funkcija-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Uključi/isključi podsekciju Funkcija</span> </button> <ul id="toc-Funkcija-sublist" class="vector-toc-list"> <li id="toc-Sazrijevanje_T-ćelija" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Sazrijevanje_T-ćelija"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.1</span> <span>Sazrijevanje T-ćelija</span> </div> </a> <ul id="toc-Sazrijevanje_T-ćelija-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Pozitivna_selekcija" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Pozitivna_selekcija"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.2</span> <span>Pozitivna selekcija</span> </div> </a> <ul id="toc-Pozitivna_selekcija-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Negativna_selekcija" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Negativna_selekcija"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.3</span> <span>Negativna selekcija</span> </div> </a> <ul id="toc-Negativna_selekcija-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Klinički_značaj" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Klinički_značaj"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Klinički značaj</span> </div> </a> <button aria-controls="toc-Klinički_značaj-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Uključi/isključi podsekciju Klinički značaj</span> </button> <ul id="toc-Klinički_značaj-sublist" class="vector-toc-list"> <li id="toc-Imunodeficijencija" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Imunodeficijencija"> <div class="vector-toc-text"> <span class="vector-toc-numb">4.1</span> <span>Imunodeficijencija</span> </div> </a> <ul id="toc-Imunodeficijencija-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Historija" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Historija"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Historija</span> </div> </a> <ul id="toc-Historija-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Dodatne_slike" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Dodatne_slike"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Dodatne slike</span> </div> </a> <ul id="toc-Dodatne_slike-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reference" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Reference"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Reference</span> </div> </a> <ul id="toc-Reference-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Dopunska_literatura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Dopunska_literatura"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>Dopunska literatura</span> </div> </a> <ul id="toc-Dopunska_literatura-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Vanjski_linkovi" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Vanjski_linkovi"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>Vanjski linkovi</span> </div> </a> <ul id="toc-Vanjski_linkovi-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Sadržaj" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Uključi/isključi sadržaj" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Uključi/isključi sadržaj</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Timus</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Idi na članak na drugom jeziku. Dostupno na 75 jezika" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-75" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">75 jezika</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%BA%D8%AF%D8%A9_%D8%B2%D8%B9%D8%AA%D8%B1%D9%8A%D8%A9" title="غدة زعترية – arapski" lang="ar" hreflang="ar" data-title="غدة زعترية" data-language-autonym="العربية" data-language-local-name="arapski" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-az mw-list-item"><a href="https://az.wikipedia.org/wiki/%C3%87%C9%99ng%C9%99l%C9%99b%C9%99nz%C9%99r_v%C9%99zi" title="Çəngələbənzər vəzi – azerbejdžanski" lang="az" hreflang="az" data-title="Çəngələbənzər vəzi" data-language-autonym="Azərbaycanca" data-language-local-name="azerbejdžanski" class="interlanguage-link-target"><span>Azərbaycanca</span></a></li><li class="interlanguage-link interwiki-be-x-old mw-list-item"><a href="https://be-tarask.wikipedia.org/wiki/%D0%92%D1%96%D0%BB%D0%B0%D0%B2%D0%B0%D1%82%D0%B0%D1%8F_%D0%B7%D0%B0%D0%BB%D0%BE%D0%B7%D0%B0" title="Вілаватая залоза – Belarusian (Taraškievica orthography)" lang="be-tarask" hreflang="be-tarask" data-title="Вілаватая залоза" data-language-autonym="Беларуская (тарашкевіца)" data-language-local-name="Belarusian (Taraškievica orthography)" class="interlanguage-link-target"><span>Беларуская (тарашкевіца)</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%A2%D0%B8%D0%BC%D1%83%D1%81" title="Тимус – bugarski" lang="bg" hreflang="bg" data-title="Тимус" data-language-autonym="Български" data-language-local-name="bugarski" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%A5%E0%A6%BE%E0%A6%87%E0%A6%AE%E0%A6%BE%E0%A6%B8" title="থাইমাস – bengalski" lang="bn" hreflang="bn" data-title="থাইমাস" data-language-autonym="বাংলা" data-language-local-name="bengalski" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Tim" title="Tim – katalonski" lang="ca" hreflang="ca" data-title="Tim" data-language-autonym="Català" data-language-local-name="katalonski" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-ckb mw-list-item"><a href="https://ckb.wikipedia.org/wiki/%D8%AA%D8%A7%DB%8C%D9%85%DB%86%D8%B3" title="تایمۆس – centralnokurdski" lang="ckb" hreflang="ckb" data-title="تایمۆس" data-language-autonym="کوردی" data-language-local-name="centralnokurdski" class="interlanguage-link-target"><span>کوردی</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Brzl%C3%ADk" title="Brzlík – češki" lang="cs" hreflang="cs" data-title="Brzlík" data-language-autonym="Čeština" data-language-local-name="češki" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Thymws" title="Thymws – velški" lang="cy" hreflang="cy" data-title="Thymws" data-language-autonym="Cymraeg" data-language-local-name="velški" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Brissel" title="Brissel – danski" lang="da" hreflang="da" data-title="Brissel" data-language-autonym="Dansk" data-language-local-name="danski" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Thymus" title="Thymus – njemački" lang="de" hreflang="de" data-title="Thymus" data-language-autonym="Deutsch" data-language-local-name="njemački" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%98%CF%8D%CE%BC%CE%BF%CF%82_%CE%B1%CE%B4%CE%AD%CE%BD%CE%B1%CF%82" title="Θύμος αδένας – grčki" lang="el" hreflang="el" data-title="Θύμος αδένας" data-language-autonym="Ελληνικά" data-language-local-name="grčki" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en badge-Q17437798 badge-goodarticle mw-list-item" title="dobar članak"><a href="https://en.wikipedia.org/wiki/Thymus" title="Thymus – engleski" lang="en" hreflang="en" data-title="Thymus" data-language-autonym="English" data-language-local-name="engleski" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Timuso" title="Timuso – esperanto" lang="eo" hreflang="eo" data-title="Timuso" data-language-autonym="Esperanto" data-language-local-name="esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Timo" title="Timo – španski" lang="es" hreflang="es" data-title="Timo" data-language-autonym="Español" data-language-local-name="španski" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/T%C3%BC%C3%BCmus" title="Tüümus – estonski" lang="et" hreflang="et" data-title="Tüümus" data-language-autonym="Eesti" data-language-local-name="estonski" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Timo" title="Timo – baskijski" lang="eu" hreflang="eu" data-title="Timo" data-language-autonym="Euskara" data-language-local-name="baskijski" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%AA%DB%8C%D9%85%D9%88%D8%B3" title="تیموس – perzijski" lang="fa" hreflang="fa" data-title="تیموس" data-language-autonym="فارسی" data-language-local-name="perzijski" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Kateenkorva" title="Kateenkorva – finski" lang="fi" hreflang="fi" data-title="Kateenkorva" data-language-autonym="Suomi" data-language-local-name="finski" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Thymus_(anatomie)" title="Thymus (anatomie) – francuski" lang="fr" hreflang="fr" data-title="Thymus (anatomie)" data-language-autonym="Français" data-language-local-name="francuski" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ga mw-list-item"><a href="https://ga.wikipedia.org/wiki/Faireog_th%C3%ADmis" title="Faireog thímis – irski" lang="ga" hreflang="ga" data-title="Faireog thímis" data-language-autonym="Gaeilge" data-language-local-name="irski" class="interlanguage-link-target"><span>Gaeilge</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Timo" title="Timo – galicijski" lang="gl" hreflang="gl" data-title="Timo" data-language-autonym="Galego" data-language-local-name="galicijski" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%AA%D7%99%D7%9E%D7%95%D7%A1" title="תימוס – hebrejski" lang="he" hreflang="he" data-title="תימוס" data-language-autonym="עברית" data-language-local-name="hebrejski" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%A5%E0%A4%BE%E0%A4%87%E0%A4%AE%E0%A4%B8_%E0%A4%97%E0%A5%8D%E0%A4%B0%E0%A4%82%E0%A4%A5%E0%A4%BF" title="थाइमस ग्रंथि – hindi" lang="hi" hreflang="hi" data-title="थाइमस ग्रंथि" data-language-autonym="हिन्दी" data-language-local-name="hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Timus" title="Timus – hrvatski" lang="hr" hreflang="hr" data-title="Timus" data-language-autonym="Hrvatski" data-language-local-name="hrvatski" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Csecsem%C5%91mirigy" title="Csecsemőmirigy – mađarski" lang="hu" hreflang="hu" data-title="Csecsemőmirigy" data-language-autonym="Magyar" data-language-local-name="mađarski" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%88%D6%82%D6%80%D6%81%D5%A1%D5%A3%D5%A5%D5%B2%D5%B1" title="Ուրցագեղձ – armenski" lang="hy" hreflang="hy" data-title="Ուրցագեղձ" data-language-autonym="Հայերեն" data-language-local-name="armenski" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-ia mw-list-item"><a href="https://ia.wikipedia.org/wiki/Thymo" title="Thymo – interlingva" lang="ia" hreflang="ia" data-title="Thymo" data-language-autonym="Interlingua" data-language-local-name="interlingva" class="interlanguage-link-target"><span>Interlingua</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Timus_(anatomi)" title="Timus (anatomi) – indonezijski" lang="id" hreflang="id" data-title="Timus (anatomi)" data-language-autonym="Bahasa Indonesia" data-language-local-name="indonezijski" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-io mw-list-item"><a href="https://io.wikipedia.org/wiki/Timuso" title="Timuso – ido" lang="io" hreflang="io" data-title="Timuso" data-language-autonym="Ido" data-language-local-name="ido" class="interlanguage-link-target"><span>Ido</span></a></li><li class="interlanguage-link interwiki-is mw-list-item"><a href="https://is.wikipedia.org/wiki/H%C3%B3starkirtill" title="Hóstarkirtill – islandski" lang="is" hreflang="is" data-title="Hóstarkirtill" data-language-autonym="Íslenska" data-language-local-name="islandski" class="interlanguage-link-target"><span>Íslenska</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Timo_(anatomia)" title="Timo (anatomia) – italijanski" lang="it" hreflang="it" data-title="Timo (anatomia)" data-language-autonym="Italiano" data-language-local-name="italijanski" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E8%83%B8%E8%85%BA" title="胸腺 – japanski" lang="ja" hreflang="ja" data-title="胸腺" data-language-autonym="日本語" data-language-local-name="japanski" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-jv mw-list-item"><a href="https://jv.wikipedia.org/wiki/Timus" title="Timus – javanski" lang="jv" hreflang="jv" data-title="Timus" data-language-autonym="Jawa" data-language-local-name="javanski" class="interlanguage-link-target"><span>Jawa</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/%D0%90%D0%B9%D1%8B%D1%80%D1%88%D0%B0_%D0%B1%D0%B5%D0%B7" title="Айырша без – kazaški" lang="kk" hreflang="kk" data-title="Айырша без" data-language-autonym="Қазақша" data-language-local-name="kazaški" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-km mw-list-item"><a href="https://km.wikipedia.org/wiki/%E1%9E%80%E1%9F%92%E1%9E%9A%E1%9E%96%E1%9F%81%E1%9E%89%E1%9E%91%E1%9E%B8%E1%9E%98%E1%9E%BB%E1%9E%9F" title="ក្រពេញទីមុស – kmerski" lang="km" hreflang="km" data-title="ក្រពេញទីមុស" data-language-autonym="ភាសាខ្មែរ" data-language-local-name="kmerski" class="interlanguage-link-target"><span>ភាសាខ្មែរ</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EA%B0%80%EC%8A%B4%EC%83%98" title="가슴샘 – korejski" lang="ko" hreflang="ko" data-title="가슴샘" data-language-autonym="한국어" data-language-local-name="korejski" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-ku mw-list-item"><a href="https://ku.wikipedia.org/wiki/T%C3%AEmus" title="Tîmus – kurdski" lang="ku" hreflang="ku" data-title="Tîmus" data-language-autonym="Kurdî" data-language-local-name="kurdski" class="interlanguage-link-target"><span>Kurdî</span></a></li><li class="interlanguage-link interwiki-ky mw-list-item"><a href="https://ky.wikipedia.org/wiki/%D0%91%D0%BE%D0%B3%D0%BE%D0%BA_%D0%B1%D0%B5%D0%B7%D0%B8" title="Богок бези – kirgiški" lang="ky" hreflang="ky" data-title="Богок бези" data-language-autonym="Кыргызча" data-language-local-name="kirgiški" class="interlanguage-link-target"><span>Кыргызча</span></a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/Thymus_(glandula)" title="Thymus (glandula) – latinski" lang="la" hreflang="la" data-title="Thymus (glandula)" data-language-autonym="Latina" data-language-local-name="latinski" class="interlanguage-link-target"><span>Latina</span></a></li><li class="interlanguage-link interwiki-lfn mw-list-item"><a href="https://lfn.wikipedia.org/wiki/Timo" title="Timo – Lingua Franca Nova" lang="lfn" hreflang="lfn" data-title="Timo" data-language-autonym="Lingua Franca Nova" data-language-local-name="Lingua Franca Nova" class="interlanguage-link-target"><span>Lingua Franca Nova</span></a></li><li class="interlanguage-link interwiki-lmo mw-list-item"><a href="https://lmo.wikipedia.org/wiki/Tim_(orghen)" title="Tim (orghen) – lombardski" lang="lmo" hreflang="lmo" data-title="Tim (orghen)" data-language-autonym="Lombard" data-language-local-name="lombardski" class="interlanguage-link-target"><span>Lombard</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/U%C5%BEkr%C5%AB%C4%8Dio_liauka" title="Užkrūčio liauka – litvanski" lang="lt" hreflang="lt" data-title="Užkrūčio liauka" data-language-autonym="Lietuvių" data-language-local-name="litvanski" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-lv mw-list-item"><a href="https://lv.wikipedia.org/wiki/Aizkr%C5%ABtes_dziedzeris" title="Aizkrūtes dziedzeris – latvijski" lang="lv" hreflang="lv" data-title="Aizkrūtes dziedzeris" data-language-autonym="Latviešu" data-language-local-name="latvijski" class="interlanguage-link-target"><span>Latviešu</span></a></li><li class="interlanguage-link interwiki-map-bms mw-list-item"><a href="https://map-bms.wikipedia.org/wiki/Timus" title="Timus – Banyumasan" lang="jv-x-bms" hreflang="jv-x-bms" data-title="Timus" data-language-autonym="Basa Banyumasan" data-language-local-name="Banyumasan" class="interlanguage-link-target"><span>Basa Banyumasan</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%93%D1%80%D0%B0%D0%B4%D0%BD%D0%B0_%D0%B6%D0%BB%D0%B5%D0%B7%D0%B4%D0%B0" title="Градна жлезда – makedonski" lang="mk" hreflang="mk" data-title="Градна жлезда" data-language-autonym="Македонски" data-language-local-name="makedonski" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%A4%E0%B5%88%E0%B4%AE%E0%B4%B8%E0%B5%8D_%E0%B4%97%E0%B5%8D%E0%B4%B0%E0%B4%A8%E0%B5%8D%E0%B4%A5%E0%B4%BF" title="തൈമസ് ഗ്രന്ഥി – malajalam" lang="ml" hreflang="ml" data-title="തൈമസ് ഗ്രന്ഥി" data-language-autonym="മലയാളം" data-language-local-name="malajalam" class="interlanguage-link-target"><span>മലയാളം</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Timus" title="Timus – malajski" lang="ms" hreflang="ms" data-title="Timus" data-language-autonym="Bahasa Melayu" data-language-local-name="malajski" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Thymus_(orgaan)" title="Thymus (orgaan) – nizozemski" lang="nl" hreflang="nl" data-title="Thymus (orgaan)" data-language-autonym="Nederlands" data-language-local-name="nizozemski" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-nn mw-list-item"><a href="https://nn.wikipedia.org/wiki/Bris_i_anatomi" title="Bris i anatomi – norveški (Nynorsk)" lang="nn" hreflang="nn" data-title="Bris i anatomi" data-language-autonym="Norsk nynorsk" data-language-local-name="norveški (Nynorsk)" class="interlanguage-link-target"><span>Norsk nynorsk</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Brissel" title="Brissel – norveški (Bokmal)" lang="nb" hreflang="nb" data-title="Brissel" data-language-autonym="Norsk bokmål" data-language-local-name="norveški (Bokmal)" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Grasica" title="Grasica – poljski" lang="pl" hreflang="pl" data-title="Grasica" data-language-autonym="Polski" data-language-local-name="poljski" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Timo" title="Timo – portugalski" lang="pt" hreflang="pt" data-title="Timo" data-language-autonym="Português" data-language-local-name="portugalski" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Timus" title="Timus – rumunski" lang="ro" hreflang="ro" data-title="Timus" data-language-autonym="Română" data-language-local-name="rumunski" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%A2%D0%B8%D0%BC%D1%83%D1%81" title="Тимус – ruski" lang="ru" hreflang="ru" data-title="Тимус" data-language-autonym="Русский" data-language-local-name="ruski" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sco mw-list-item"><a href="https://sco.wikipedia.org/wiki/Thymus" title="Thymus – škotski" lang="sco" hreflang="sco" data-title="Thymus" data-language-autonym="Scots" data-language-local-name="škotski" class="interlanguage-link-target"><span>Scots</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Timus" title="Timus – srpskohrvatski" lang="sh" hreflang="sh" data-title="Timus" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="srpskohrvatski" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Thymus" title="Thymus – Simple English" lang="en-simple" hreflang="en-simple" data-title="Thymus" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Detsk%C3%A1_%C5%BE%C4%BEaza" title="Detská žľaza – slovački" lang="sk" hreflang="sk" data-title="Detská žľaza" data-language-autonym="Slovenčina" data-language-local-name="slovački" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Pri%C5%BEeljc" title="Priželjc – slovenski" lang="sl" hreflang="sl" data-title="Priželjc" data-language-autonym="Slovenščina" data-language-local-name="slovenski" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%93%D1%80%D1%83%D0%B4%D0%BD%D0%B0_%D0%B6%D0%BB%D0%B5%D0%B7%D0%B4%D0%B0" title="Грудна жлезда – srpski" lang="sr" hreflang="sr" data-title="Грудна жлезда" data-language-autonym="Српски / srpski" data-language-local-name="srpski" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Br%C3%A4ss" title="Bräss – švedski" lang="sv" hreflang="sv" data-title="Bräss" data-language-autonym="Svenska" data-language-local-name="švedski" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a href="https://ta.wikipedia.org/wiki/%E0%AE%A4%E0%AF%88%E0%AE%AE%E0%AE%B8%E0%AF%8D_%E0%AE%9A%E0%AF%81%E0%AE%B0%E0%AE%AA%E0%AF%8D%E0%AE%AA%E0%AE%BF" title="தைமஸ் சுரப்பி – tamilski" lang="ta" hreflang="ta" data-title="தைமஸ் சுரப்பி" data-language-autonym="தமிழ்" data-language-local-name="tamilski" class="interlanguage-link-target"><span>தமிழ்</span></a></li><li class="interlanguage-link interwiki-te mw-list-item"><a href="https://te.wikipedia.org/wiki/%E0%B0%A5%E0%B1%88%E0%B0%AE%E0%B0%B8%E0%B1%8D_%E0%B0%97%E0%B1%8D%E0%B0%B0%E0%B0%82%E0%B0%A5%E0%B0%BF" title="థైమస్ గ్రంథి – telugu" lang="te" hreflang="te" data-title="థైమస్ గ్రంథి" data-language-autonym="తెలుగు" data-language-local-name="telugu" class="interlanguage-link-target"><span>తెలుగు</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%95%E0%B9%88%E0%B8%AD%E0%B8%A1%E0%B9%84%E0%B8%97%E0%B8%A1%E0%B8%B1%E0%B8%AA" title="ต่อมไทมัส – tajlandski" lang="th" hreflang="th" data-title="ต่อมไทมัส" data-language-autonym="ไทย" data-language-local-name="tajlandski" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Tim%C3%BCs" title="Timüs – turski" lang="tr" hreflang="tr" data-title="Timüs" data-language-autonym="Türkçe" data-language-local-name="turski" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-ug mw-list-item"><a href="https://ug.wikipedia.org/wiki/%D8%AA%DB%86%D8%B4_%D8%A8%DB%90%D8%B2%D9%89" title="تۆش بېزى – ujgurski" lang="ug" hreflang="ug" data-title="تۆش بېزى" data-language-autonym="ئۇيغۇرچە / Uyghurche" data-language-local-name="ujgurski" class="interlanguage-link-target"><span>ئۇيغۇرچە / Uyghurche</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%A2%D0%B8%D0%BC%D1%83%D1%81" title="Тимус – ukrajinski" lang="uk" hreflang="uk" data-title="Тимус" data-language-autonym="Українська" data-language-local-name="ukrajinski" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-ur mw-list-item"><a href="https://ur.wikipedia.org/wiki/%D8%AA%D9%88%D8%AA%DB%81" title="توتہ – urdu" lang="ur" hreflang="ur" data-title="توتہ" data-language-autonym="اردو" data-language-local-name="urdu" class="interlanguage-link-target"><span>اردو</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Tuy%E1%BA%BFn_%E1%BB%A9c" title="Tuyến ức – vijetnamski" lang="vi" hreflang="vi" data-title="Tuyến ức" data-language-autonym="Tiếng Việt" data-language-local-name="vijetnamski" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-wa mw-list-item"><a href="https://wa.wikipedia.org/wiki/Timusse_(organe)" title="Timusse (organe) – valun" lang="wa" hreflang="wa" data-title="Timusse (organe)" data-language-autonym="Walon" data-language-local-name="valun" class="interlanguage-link-target"><span>Walon</span></a></li><li class="interlanguage-link interwiki-war mw-list-item"><a href="https://war.wikipedia.org/wiki/Timus_(anatomiya)" title="Timus (anatomiya) – varej" lang="war" hreflang="war" data-title="Timus (anatomiya)" data-language-autonym="Winaray" data-language-local-name="varej" class="interlanguage-link-target"><span>Winaray</span></a></li><li class="interlanguage-link interwiki-wuu mw-list-item"><a href="https://wuu.wikipedia.org/wiki/%E8%83%B8%E8%85%BA" title="胸腺 – Wu kineski" lang="wuu" hreflang="wuu" data-title="胸腺" data-language-autonym="吴语" data-language-local-name="Wu kineski" class="interlanguage-link-target"><span>吴语</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E8%83%B8%E8%85%BA" title="胸腺 – kineski" lang="zh" hreflang="zh" data-title="胸腺" data-language-autonym="中文" data-language-local-name="kineski" class="interlanguage-link-target"><span>中文</span></a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a href="https://zh-yue.wikipedia.org/wiki/%E8%83%B8%E8%85%BA" title="胸腺 – kantonski" lang="yue" hreflang="yue" data-title="胸腺" data-language-autonym="粵語" data-language-local-name="kantonski" class="interlanguage-link-target"><span>粵語</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q163987#sitelinks-wikipedia" title="Uredi međujezičke linkove" class="wbc-editpage">Uredi veze</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Imenski prostori"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul 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class="mw-content-ltr mw-parser-output" lang="bs" dir="ltr"><div role="note" class="hatnote navigation-not-searchable">Razlikovati: <a href="/wiki/Thymus" title="Thymus">Thymus</a>.</div> <style data-mw-deduplicate="TemplateStyles:r3638947">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}body.skin-minerva .mw-parser-output .infobox-header,body.skin-minerva .mw-parser-output .infobox-subheader,body.skin-minerva .mw-parser-output .infobox-above,body.skin-minerva .mw-parser-output .infobox-title,body.skin-minerva .mw-parser-output .infobox-image,body.skin-minerva .mw-parser-output .infobox-full-data,body.skin-minerva .mw-parser-output .infobox-below{text-align:center}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data div{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data div{background:#1f1f23!important;color:#f8f9fa}}</style><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above" style="background-color:dimgray; color: white">Timus<br />(Grudna žlijezda)</th></tr><tr><td colspan="2" class="infobox-image"><span typeof="mw:File"><a href="/wiki/Datoteka:Illu_thymus.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/cf/Illu_thymus.jpg/280px-Illu_thymus.jpg" decoding="async" width="280" height="311" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/c/cf/Illu_thymus.jpg 1.5x" data-file-width="350" data-file-height="389" /></a></span></td></tr><tr><td colspan="2" class="infobox-image"><span typeof="mw:File"><span><video id="mwe_player_0" 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src="//upload.wikimedia.org/wikipedia/commons/transcoded/7/7a/Function_of_the_thymus_-_Inside_the_Thymus.webm/Function_of_the_thymus_-_Inside_the_Thymus.webm.1080p.vp9.webm" type="video/webm; codecs="vp9, opus"" data-transcodekey="1080p.vp9.webm" data-width="1920" data-height="1080" /><source src="//upload.wikimedia.org/wikipedia/commons/7/7a/Function_of_the_thymus_-_Inside_the_Thymus.webm" type="video/webm; codecs="vp8, vorbis"" data-width="1920" data-height="1080" /><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/7/7a/Function_of_the_thymus_-_Inside_the_Thymus.webm/Function_of_the_thymus_-_Inside_the_Thymus.webm.144p.mjpeg.mov" type="video/quicktime" data-transcodekey="144p.mjpeg.mov" data-width="256" data-height="144" /><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/7/7a/Function_of_the_thymus_-_Inside_the_Thymus.webm/Function_of_the_thymus_-_Inside_the_Thymus.webm.240p.vp9.webm" type="video/webm; codecs="vp9, opus"" data-transcodekey="240p.vp9.webm" data-width="426" data-height="240" /><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/7/7a/Function_of_the_thymus_-_Inside_the_Thymus.webm/Function_of_the_thymus_-_Inside_the_Thymus.webm.360p.vp9.webm" type="video/webm; codecs="vp9, opus"" data-transcodekey="360p.vp9.webm" data-width="640" data-height="360" /><source src="//upload.wikimedia.org/wikipedia/commons/transcoded/7/7a/Function_of_the_thymus_-_Inside_the_Thymus.webm/Function_of_the_thymus_-_Inside_the_Thymus.webm.360p.webm" type="video/webm; codecs="vp8, vorbis"" data-transcodekey="360p.webm" data-width="640" data-height="360" /><track src="https://commons.wikimedia.org/w/api.php?action=timedtext&title=File%3AFunction_of_the_thymus_-_Inside_the_Thymus.webm&lang=en&trackformat=vtt&origin=%2A" kind="subtitles" type="text/vtt" srclang="en" label="English ‪(en)‬" data-dir="ltr" /><track src="https://commons.wikimedia.org/w/api.php?action=timedtext&title=File%3AFunction_of_the_thymus_-_Inside_the_Thymus.webm&lang=fr&trackformat=vtt&origin=%2A" kind="subtitles" type="text/vtt" srclang="fr" label="français ‪(fr)‬" data-dir="ltr" /><track src="https://commons.wikimedia.org/w/api.php?action=timedtext&title=File%3AFunction_of_the_thymus_-_Inside_the_Thymus.webm&lang=ru&trackformat=vtt&origin=%2A" kind="subtitles" type="text/vtt" srclang="ru" label="русский ‪(ru)‬" data-dir="ltr" /></video></span></span></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #efefef">Detalji</th></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Embriologija" title="Embriologija">Prekursor</a></th><td class="infobox-data"><a href="/w/index.php?title=%C5%BDdrijelna_torbica&action=edit&redlink=1" class="new" title="Ždrijelna torbica (stranica ne postoji)">Treća ždrijelna vrećica</a></td></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Organski_sistem" title="Organski sistem">Sistem</a></th><td class="infobox-data"><a href="/wiki/Limfni_sistem" title="Limfni sistem">Limfni</a>, dio <a href="/wiki/Imunski_sistem" class="mw-redirect" title="Imunski sistem">imunskog sistema</a></td></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Limfa" title="Limfa">Limfa</a></th><td class="infobox-data"><a href="/w/index.php?title=Traheobronhijski_limni_%C4%8Dvor&action=edit&redlink=1" class="new" title="Traheobronhijski limni čvor (stranica ne postoji)">Traheobronhijski</a>, <a href="/w/index.php?title=Parasternumski_limfni_%C4%8Dvorovi&action=edit&redlink=1" class="new" title="Parasternumski limfni čvorovi (stranica ne postoji)">parasternumski čvorovi</a></td></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em">Funkcija</th><td class="infobox-data">Podrška razvoju djelotvornih <a href="/wiki/T-%C4%87elija" title="T-ćelija">T-ćelija</a></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #efefef">Identifikatori</th></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Latinski_jezik" title="Latinski jezik">Latinski</a></th><td class="infobox-data">'<b>Thymus'</b></td></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=D013950">D013950</a></td></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Terminologia_Anatomica" title="Terminologia Anatomica">TA98</a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="http://www.unifr.ch/ifaa/Public/EntryPage/TA98%20Tree/Entity%20TA98%20EN/13.1.02.001%20Entity%20TA98%20EN.htm">A13.1.02.001</a></td></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/wiki/Terminologia_Anatomica" title="Terminologia Anatomica">TA2</a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://ta2viewer.openanatomy.org/?id=5152">5152</a></td></tr><tr><th scope="row" class="infobox-label" style="padding-right:0.25em"><a href="/w/index.php?title=Foundational_Model_of_Anatomy&action=edit&redlink=1" class="new" title="Foundational Model of Anatomy (stranica ne postoji)">FMA</a></th><td class="infobox-data"><a rel="nofollow" class="external text" href="http://fme.biostr.washington.edu/FME/index.jsp?fmaid=9607">9607</a></td></tr><tr><td colspan="2" class="infobox-below"><a href="/wiki/Anatomska_terminologija" title="Anatomska terminologija">Anatomska terminologija</a><div style="text-align: right;"><small class="noprint">[<a href="https://www.wikidata.org/wiki/Q163987" class="extiw" title="d:Q163987">uredi na Wikidata</a>]</small></div></td></tr></tbody></table> <p><b>Timus</b> je specijalizirani primarni <a href="/wiki/Limfni_sistem" title="Limfni sistem">limfoidni organ</a> <a href="/wiki/Imunski_sistem" class="mw-redirect" title="Imunski sistem">imunskog sistema</a>. Unutar timusa sazrevaju <a href="/wiki/T-%C4%87elija" title="T-ćelija">timusne ćelije</a> <a href="/wiki/Limfociti" title="Limfociti">limfociti</a> ili <a href="/wiki/T-%C4%87elije" class="mw-redirect" title="T-ćelije">T-ćelije</a> . T-ćelije su ključne za <a href="/wiki/Adaptivni_imunski_sistem" title="Adaptivni imunski sistem">adaptivni imunski sistem</a>, gdje se tijelo posebno prilagođava stranim osvajačima. Timus se nalazi u gornjem prednjem dijelu grudi, u prednjem <a href="/w/index.php?title=Mediastinum&action=edit&redlink=1" class="new" title="Mediastinum (stranica ne postoji)">gornjrm mediastinumu</a>, iza <a href="/wiki/Grudna_kost" title="Grudna kost">grudne kosti</a> i ispred <a href="/wiki/Srce" title="Srce">srca</a>. Sastoji se od dva režnja, od kojih se svaki sastoji od središnje srži i vanjske kore, okružene kapsulom. </p><p>Timus se sastoji od nezrelih <a href="/wiki/T-%C4%87elija" title="T-ćelija">T-ćelija</a> zvanih <a href="/w/index.php?title=Timociti&action=edit&redlink=1" class="new" title="Timociti (stranica ne postoji)">timociti</a>, kao i ćelija sluznice zvanih <a href="/w/index.php?title=Epitelne_%C4%87elije&action=edit&redlink=1" class="new" title="Epitelne ćelije (stranica ne postoji)">epitelne ćelije</a> koje pomažu timocitima u razvoju. T-ćelije koje se uspješno razviju na odgovarajući način, reagiraju sa <a href="/wiki/Glavni_kompleks_histokompatibilnosti" title="Glavni kompleks histokompatibilnosti">MHC-om</a>, imunskim receptorima tijela (koji se nazivaju <i> pozitivna selekcija </i>), a ne protiv proteina u tijelu (zvanih <i>negativna selekcija</i>). Timus je najveći i najaktivniji tokom neonatalnog i predadolescentnog perioda. U ranim tinejdžerskim godinama <a href="/w/index.php?title=Timusna_involucija&action=edit&redlink=1" class="new" title="Timusna involucija (stranica ne postoji)">timus počinje smanjivati i veličinu i aktivnost</a> i tkivo mu se postepeno zamjenjuje <a href="/wiki/Masno_tkivo" title="Masno tkivo">masnim tkivom</a>. Ipak, razvoj nekih T-ćelija nastavlja se i tokom života odraslih.<sup id="cite_ref-Greys2008_1-0" class="reference"><a href="#cite_note-Greys2008-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Greys2016_2-0" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>Abnormalnosti timusa mogu rezultirati smanjenim brojem T-ćelija i autoimunskim bolestima kao što su <a href="/w/index.php?title=Autoimunski_poliendokrini_sindrom_tip_1&action=edit&redlink=1" class="new" title="Autoimunski poliendokrini sindrom tip 1 (stranica ne postoji)">autoimunski poliendokrini sindrom tip 1</a> i <i><a href="/w/index.php?title=Miastenija_gravis&action=edit&redlink=1" class="new" title="Miastenija gravis (stranica ne postoji)">miastenija gravis</a></i>. Oni su često povezani sa rakom tkiva timusa, koji se naziva <a href="/w/index.php?title=Timom&action=edit&redlink=1" class="new" title="Timom (stranica ne postoji)">timom</a>, ili tkivima koja proizlaze iz nezrelih limfocita, poput T-ćelija, zvanih <a href="/wiki/Limfom" title="Limfom">limfom</a>. Uklanjanje timusa naziva se <a href="/w/index.php?title=Timetomija&action=edit&redlink=1" class="new" title="Timetomija (stranica ne postoji)">timetomija</a>. Iako je timus identificiran kao dio tijela još u doba <a href="/wiki/Drevna_Gr%C4%8Dka" class="mw-redirect" title="Drevna Grčka">Drevni Grci</a>, tek je od 1960-ih funkcija timusa u imunskom sistemu postala jasnija. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Struktura">Struktura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=1" title="Uredi odlomak "Struktura"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=1" title="Edit section's source code: Struktura"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Timus je organ koji se nalazi ispod <a href="/wiki/Grudna_kost" title="Grudna kost">sternuma</a> u gornjem prednjem dijelu grudi, protežući se prema vratu. U djece je ružičasto-siv, mehak i režnjevit na svojim površinama. Pri rođenju je dugačak oko 4–6 cm, širok 2,5–5 cm i debeo oko 1 cm. Povećava se do <a href="/wiki/Pubertet" title="Pubertet">puberteta</a>, kada može imati veličinu oko 40–50 g, nakon čega se smanjuje u veličini u procesu poznatom kao <a href="/w/index.php?title=Involucija&action=edit&redlink=1" class="new" title="Involucija (stranica ne postoji)">involucija</a>. </p><p>Timus se sastoji od dva režnja koji se sastaju u gornjoj srednjoj liniji i protežu se od ispod <a href="/wiki/%C5%A0titasta_%C5%BElijezda" title="Štitasta žlijezda">štitaste žlijezde</a> u vratu do nižeg nivoa hrskavice četvrtog rebra.<sup id="cite_ref-Grays2008_3-0" class="reference"><a href="#cite_note-Grays2008-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Režnjevi su prekriveni kapsulom.<sup id="cite_ref-Robbins9th_4-0" class="reference"><a href="#cite_note-Robbins9th-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> Nalazi se na <a href="/wiki/Perikard" title="Perikard">perikardu</a> i odvojen je od <a href="/wiki/Aortni_luk" title="Aortni luk">aortnog luka</a> i <a href="/wiki/Aorta" title="Aorta">velikih krvnih sudova</a> slojem <a href="/wiki/Fascija" title="Fascija">fascija</a>. Lijeva <a href="/w/index.php?title=Brahiocefalna_vena&action=edit&redlink=1" class="new" title="Brahiocefalna vena (stranica ne postoji)">brahiocefalna vena</a> može čak biti ugrađena u timus. U vratu leži na prednjoj i bočnoj strani <a href="/wiki/Du%C5%A1nik" title="Dušnik">dušnika</a>, iza <a href="/w/index.php?title=Sternohioidni_mi%C5%A1i%C4%87&action=edit&redlink=1" class="new" title="Sternohioidni mišić (stranica ne postoji)">sternohioidnog</a> i <a href="/w/index.php?title=Sternotiroidni_mi%C5%A1i%C4%87&action=edit&redlink=1" class="new" title="Sternotiroidni mišić (stranica ne postoji)">sternotiroidnog mišića</a>.<sup id="cite_ref-Greys2008_1-1" class="reference"><a href="#cite_note-Greys2008-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Mikroanatomija">Mikroanatomija</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=2" title="Uredi odlomak "Mikroanatomija"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=2" title="Edit section's source code: Mikroanatomija"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Timus se sastoji od dva režnja, spojena u sredini, okružena kapsulom koja se produžava krvnim sudovima u unutrašnjost.<sup id="cite_ref-Grays2016_5-0" class="reference"><a href="#cite_note-Grays2016-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> Režnjevi se sastoje od vanjske kore, bogate ćelijama i unutrašnjeg manje guste srži (medule). Režnjevi su podijeljeni u manje režnjiće, promjera 0,5–2 mm, između kojih se istiskuju zračeći umeci iz kapsule duž pregrada. </p><p>Korteks (kora) se uglavnom sastoji od <a href="/wiki/Timocit" title="Timocit">timocita</a> i epitelnih ćelija. Timociti, nezrele <a href="/wiki/T-%C4%87elije" class="mw-redirect" title="T-ćelije">T-ćelije</a>, podržani su mrežom fino razgranatih <a href="/wiki/Epitel" title="Epitel">mrežastih epitelnih ćelija</a>, koja je kontinuirana sa sličnom mrežom u meduli. Ova mreža formira <a href="/w/index.php?title=Adventitia&action=edit&redlink=1" class="new" title="Adventitia (stranica ne postoji)">adventitia</a> u krvnim sudovima, koji ulaze u korteks preko pregrada u blizini spoja s medulom. U timusu se nalaze i druge ćelije, uključujući <a href="/wiki/Makrofag" title="Makrofag">makrofage</a> , <a href="/wiki/Dendritska_%C4%87elija" title="Dendritska ćelija">dendritske ćelije</a> i malu količinu <a href="/wiki/B-%C4%87elija" title="B-ćelija">B-ćelija</a> , <a href="/wiki/Neutrofil" class="mw-redirect" title="Neutrofil">neutrofila</a> i <a href="/wiki/Eozinofil" class="mw-redirect" title="Eozinofil">eozinofila</a>.<sup id="cite_ref-Robbins9th_4-1" class="reference"><a href="#cite_note-Robbins9th-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p><p>U meduli je mreža epitelnih ćelija grublja nego u korteksu, a limfoidne ćelije su relativno manje.<sup id="cite_ref-Grays2008_3-1" class="reference"><a href="#cite_note-Grays2008-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Koncentrična tijela poput gnijezda koja se nazivaju <a href="/w/index.php?title=Hassallova_tjela%C5%A1ca&action=edit&redlink=1" class="new" title="Hassallova tjelašca (stranica ne postoji)">Hassallova tjelašca</a> (zvana i <i>timusna tijela</i>) nastaju skupljanjem epitelnih ćelija srži.<sup id="cite_ref-Robbins9th_4-2" class="reference"><a href="#cite_note-Robbins9th-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> To su koncentrični, slojeviti zamotuljci <a href="/wiki/Epitel" title="Epitel">epitelnih ćelija</a> koji se povećavaju tokom života. Oni su ostaci epitelnih cijevi, koje izrastaju iz treće <a href="/w/index.php?title=%C5%BDdrijelna_vre%C4%87ica&action=edit&redlink=1" class="new" title="Ždrijelna vrećica (stranica ne postoji)">ždrijelne vrećice</a> <a href="/wiki/Embrion" class="mw-redirect" title="Embrion">embriona</a> da tvore timus.<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <ul class="gallery mw-gallery-traditional"> <li class="gallerybox" style="width: 155px"> <div class="thumb" style="width: 150px; height: 150px;"><span typeof="mw:File"><a href="/wiki/Datoteka:Thymus.JPG" class="mw-file-description" title="Mikrografija sa režnjićima timusa. Kora (dublje ljubičasto područje) okružuje manje gustu i svjetliju srž."><img alt="Mikrografija sa režnjićima timusa. Kora (dublje ljubičasto područje) okružuje manje gustu i svjetliju srž." src="//upload.wikimedia.org/wikipedia/commons/thumb/8/89/Thymus.JPG/120px-Thymus.JPG" decoding="async" width="120" height="90" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/89/Thymus.JPG/180px-Thymus.JPG 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/89/Thymus.JPG/240px-Thymus.JPG 2x" data-file-width="400" data-file-height="300" /></a></span></div> <div class="gallerytext"><a href="/wiki/Mikrografija" title="Mikrografija">Mikrografija</a> sa režnjićima timusa. Kora (dublje ljubičasto područje) okružuje manje gustu i svjetliju srž.</div> </li> <li class="gallerybox" style="width: 155px"> <div class="thumb" style="width: 150px; height: 150px;"><span typeof="mw:File"><a href="/wiki/Datoteka:Thymic_corpuscle.jpg" class="mw-file-description" title="Mikrografija Hassallovog tijela, unutar timusne srži."><img alt="Mikrografija Hassallovog tijela, unutar timusne srži." src="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/Thymic_corpuscle.jpg/81px-Thymic_corpuscle.jpg" decoding="async" width="81" height="120" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/9/94/Thymic_corpuscle.jpg/121px-Thymic_corpuscle.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/9/94/Thymic_corpuscle.jpg/162px-Thymic_corpuscle.jpg 2x" data-file-width="2510" data-file-height="3715" /></a></span></div> <div class="gallerytext"> Mikrografija Hassallovog tijela, unutar timusne srži.</div> </li> </ul> <div class="mw-heading mw-heading3"><h3 id="Opskrba_krvlju_i_nervima">Opskrba krvlju i nervima</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=3" title="Uredi odlomak "Opskrba krvlju i nervima"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=3" title="Edit section's source code: Opskrba krvlju i nervima"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Arterije" class="mw-redirect" title="Arterije">Arterije</a> koje opskrbljuju timus su grane <a href="/w/index.php?title=Unutra%C5%A1nja_grudna_arterija&action=edit&redlink=1" class="new" title="Unutrašnja grudna arterija (stranica ne postoji)">unutrašnje grudne</a> i <a href="/w/index.php?title=Donja_%C5%A1titnja%C4%8Dna_arterija&action=edit&redlink=1" class="new" title="Donja štitnjačna arterija (stranica ne postoji)">donje štitnjačne arterije</a>, s granama iz <a href="/w/index.php?title=Gornja_%C5%A1titnja%C4%8Dna_arterija&action=edit&redlink=1" class="new" title="Gornja štitnjačna arterija (stranica ne postoji)">gornje štitnjačne arterije</a>, što se ponekad viđa.<sup id="cite_ref-Greys2016_2-1" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Grane dosežu timus i pregradama kapsule putuju u područje između kore i medule, gdje ulaze u sam timus; alternativno direktno ulaze u kapsulu.<sup id="cite_ref-Greys2016_2-2" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p><a href="/wiki/Vene" class="mw-redirect" title="Vene">Vene</a> timusa završavaju se u <a href="/w/index.php?title=Lijeva_brahioceflna_vena&action=edit&redlink=1" class="new" title="Lijeva brahioceflna vena (stranica ne postoji)">lijevoj brahiocefalnoj veni</a>, <a href="/w/index.php?title=Unutra%C5%A1nja_grudna_vena&action=edit&redlink=1" class="new" title="Unutrašnja grudna vena (stranica ne postoji)">unutrašnjoj grudnoj</a> i u <a href="/w/index.php?title=Donja_%C5%A1titnja%C4%8Dna_vena&action=edit&redlink=1" class="new" title="Donja štitnjačna vena (stranica ne postoji)">donjoj štitnjačnoj veni</a>.<sup id="cite_ref-Greys2016_2-3" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Ponekad vene završavaju direktno u gornjoj šupljini veni.<sup id="cite_ref-Greys2016_2-4" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p><a href="/wiki/Limfni_sud" title="Limfni sud">Limfni sudovi</a> putuju samo dalje od timusa, prateći arterije i vene. Oni se odvode u brahiocefalne, traheobronhijalne i parazternalne <a href="/wiki/Limfni_%C4%8Dvor" title="Limfni čvor">limfne čvorove</a>.<sup id="cite_ref-Greys2016_2-5" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> <a href="/wiki/%C5%BDivci" class="mw-redirect" title="Živci">Živci</a> koji opskrbljuju timus potiču iz <a href="/wiki/Vagus" class="mw-redirect" title="Vagus">vagusnog živca</a> i cerviksa <a href="/wiki/SNS" class="mw-redirect" title="SNS">simpatičkog lanca</a>.<sup id="cite_ref-Greys2016_2-6" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Grane iz <a href="/w/index.php?title=Freni%C4%8Dni_nerv&action=edit&redlink=1" class="new" title="Frenični nerv (stranica ne postoji)">freničnog živca</a> dopiru do kapsula timusa, ali ne ulaze u sam timus.<sup id="cite_ref-Greys2016_2-7" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Varijacija">Varijacija</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=4" title="Uredi odlomak "Varijacija"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=4" title="Edit section's source code: Varijacija"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Dva režnja se malo razlikuju po veličini, a lijevi je obično viši od desnog. Timusno tkivo može se naći raštrkano na ili oko žlijezde, a povremeno i unutar štitnjače.<sup id="cite_ref-Greys2016_2-8" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Timus se u djece proteže prema gore, ponekad i do <a href="/wiki/Tireoidea" class="mw-redirect" title="Tireoidea">štitnjače</a>.<sup id="cite_ref-Greys2016_2-9" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Razvoj">Razvoj</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=5" title="Uredi odlomak "Razvoj"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=5" title="Edit section's source code: Razvoj"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/Datoteka:Gray1175.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/Gray1175.png/220px-Gray1175.png" decoding="async" width="220" height="220" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/8/83/Gray1175.png 1.5x" data-file-width="250" data-file-height="250" /></a><figcaption>Shema razvoja granatih epitelnih tijela iz grudne šupljine fetusa. I, II, III, IV. Područne vrećice.</figcaption></figure> <p>Timociti i epitel timusa imaju različito razvojno porijeklo.<sup id="cite_ref-Wheaters2013_7-0" class="reference"><a href="#cite_note-Wheaters2013-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Epitel timusa razvija se prvo, pojavljujući se kao dva izdanka, po jedan s obje strane, treće <a href="/w/index.php?title=%C5%BDdrijelna_vre%C4%87ica&action=edit&redlink=1" class="new" title="Ždrijelna vrećica (stranica ne postoji)">ždrijelne torbice</a>.<sup id="cite_ref-Wheaters2013_7-1" class="reference"><a href="#cite_note-Wheaters2013-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Ponekad uključuje i četvrtu ždrijelnu vrećicu.<sup id="cite_ref-Robbins9th_4-3" class="reference"><a href="#cite_note-Robbins9th-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> Oni se šire prema vani i unazad u okolni <a href="/wiki/Mezoderm" title="Mezoderm">mezoderm</a> i <a href="/wiki/Nervni_greben" class="mw-redirect" title="Nervni greben">nervni greben</a>– izvedeni <a href="/wiki/Mezenhim" title="Mezenhim">mezenhim</a> ispred ventralne <a href="/wiki/Aorta" title="Aorta">aorte</a>. Tu se timociti i epitel susreću i spajaju vezivnim tkivom. Otvor <a href="/wiki/%C5%BDdrijelo" title="Ždrijelo">ždrijela</a> svakog divertikuluma ubrzo je izbrisan, ali vrat tikvice zadržava se neko vrijeme kao čelijska vrpca. Daljnjom proliferacijom ćelija koje oblažu tikvicu stvaraju se pupoljci ćelija, koji postaju okruženi i izolirani napadnom <a href="/wiki/Mezoderm" title="Mezoderm">mezodermom</a>. </p><p>Epitel tvori fine režnjeve i razvija se u spužvastu strukturu. Tokom ove faze, <a href="/wiki/Hematopoeza" title="Hematopoeza">hematopoetski</a> prekursori koštane srži migriraju u timus. Normalni razvoj ovisi o interakciji između epitela i hematopoetskih <a href="/wiki/Timocit" title="Timocit">timocita</a>. <a href="/wiki/Jod" title="Jod">Jod</a> je također neophodan za razvoj i aktivnost timusa.<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Involucija">Involucija</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=6" title="Uredi odlomak "Involucija"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=6" title="Edit section's source code: Involucija"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <div role="note" class="hatnote navigation-not-searchable">Glavni članak: <a href="/w/index.php?title=Timusna_involucija&action=edit&redlink=1" class="new" title="Timusna involucija (stranica ne postoji)">Timusna involucija</a></div> <p>Timus nastavlja rasti nakon rođenja dostižući relativnu maksimalnu veličinu u <a href="/wiki/Pubertet" title="Pubertet">pubertetu</a>.<sup id="cite_ref-Greys2016_2-10" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Najaktivniji je u životu u <a href="/wiki/Fetus" title="Fetus">fetusu</a> i <a href="/wiki/Novoro%C4%91en%C4%8Dad" class="mw-redirect" title="Novorođenčad">novorođenčadi</a>. Do puberteta, povećava se na 20 – 50 grama.<sup id="cite_ref-Robbins9th_4-4" class="reference"><a href="#cite_note-Robbins9th-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> Zatim počinje smanjivati veličinu i aktivnost u procesu koji se naziva <a href="/w/index.php?title=Involucija_timusa&action=edit&redlink=1" class="new" title="Involucija timusa (stranica ne postoji)">involucija timusa</a>.<sup id="cite_ref-Wheaters2013_7-2" class="reference"><a href="#cite_note-Wheaters2013-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Nakon prve godine života količina proizvedenih <a href="/wiki/T-%C4%87elija" title="T-ćelija">T-ćelija</a> počinje padati.<sup id="cite_ref-Wheaters2013_7-3" class="reference"><a href="#cite_note-Wheaters2013-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Masno i <a href="/wiki/Vezivno_tkivo" title="Vezivno tkivo">vezivno tkivo</a> ispunjavaju dio volumena timusa.<sup id="cite_ref-Greys2016_2-11" class="reference"><a href="#cite_note-Greys2016-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Tokom involucije, timus se smanjuje u veličini i aktivnosti.<sup id="cite_ref-Wheaters2013_7-4" class="reference"><a href="#cite_note-Wheaters2013-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Masne ćelije su prisutne pri rođenju, ali se značajno povećavaju i povećavaju brojnost nakon puberteta, napadajući prvo žlijezdu sa zidova između režnjića, a zatim u kori i srži.<sup id="cite_ref-Wheaters2013_7-5" class="reference"><a href="#cite_note-Wheaters2013-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> Ovaj proces nastavlja se i u dubokoj starosti, gdje je timus možda teško otkriti bilo mikroskopom ili ljudskim okom,<sup id="cite_ref-Wheaters2013_7-6" class="reference"><a href="#cite_note-Wheaters2013-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> iako je obično težak 5 – 15 grama.<sup id="cite_ref-Robbins9th_4-5" class="reference"><a href="#cite_note-Robbins9th-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p><p>Atrofija je posljedica povećanog nivoa <a href="/wiki/Spolni_hormon" title="Spolni hormon">spolnih hormona</a> u cirkulaciji, a hemijska ili fizička kastracija odrasle osobe dovodi do povećanja veličine i aktivnosti timusa.<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> Teška bolest ili <a href="/wiki/Virus_humane_imunodeficijencije" class="mw-redirect" title="Virus humane imunodeficijencije">virus humane imunodeficijencije</a> također može rezultirati involucijom.<sup id="cite_ref-Robbins9th_4-6" class="reference"><a href="#cite_note-Robbins9th-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Funkcija">Funkcija</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=7" title="Uredi odlomak "Funkcija"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=7" title="Edit section's source code: Funkcija"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/Datoteka:Intrathymic_T_Cell_Differentiation.JPG" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Intrathymic_T_Cell_Differentiation.JPG/220px-Intrathymic_T_Cell_Differentiation.JPG" decoding="async" width="220" height="299" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Intrathymic_T_Cell_Differentiation.JPG/330px-Intrathymic_T_Cell_Differentiation.JPG 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/0e/Intrathymic_T_Cell_Differentiation.JPG/440px-Intrathymic_T_Cell_Differentiation.JPG 2x" data-file-width="3117" data-file-height="4230" /></a><figcaption>Diferencijacija T-ćelija</figcaption></figure> <div class="mw-heading mw-heading3"><h3 id="Sazrijevanje_T-ćelija"><span id="Sazrijevanje_T-.C4.87elija"></span>Sazrijevanje T-ćelija</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=8" title="Uredi odlomak "Sazrijevanje T-ćelija"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=8" title="Edit section's source code: Sazrijevanje T-ćelija"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Timus olakšava sazrijevanje <a href="/wiki/T-%C4%87elija" title="T-ćelija">T-ćelija</a>, važnog dijela <a href="/wiki/Imunski_sistem" class="mw-redirect" title="Imunski sistem">imunskog sistema</a> pružajući <a href="/w/index.php?title=%C4%86elijski_posredovani_imunitet&action=edit&redlink=1" class="new" title="Ćelijski posredovani imunitet (stranica ne postoji)">ćelijski posredovani imunitet</a>.<sup id="cite_ref-GH2016_10-0" class="reference"><a href="#cite_note-GH2016-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> T-ćelije započinju kao hematopoetske preteče iz koštane srži i migriraju u timus, gdje se nazivaju <a href="/w/index.php?title=Timociti&action=edit&redlink=1" class="new" title="Timociti (stranica ne postoji)">timociti</a>. U timusu prolaze kroz proces sazrijevanja, koji uključuje osiguravanje da ćelije reagiraju na <a href="/wiki/Antigen" title="Antigen">antigen</a> (pozitivna selekcija), ali da ne reagiraju na antigene koji se nalaze u tjelesnom tkivu ("negativna selekcija").<sup id="cite_ref-GH2016_10-1" class="reference"><a href="#cite_note-GH2016-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> Zrele T-ćelije emigriraju iz timusa da bi pružile vitalne funkcije u imunskom sistemu.<sup id="cite_ref-GH2016_10-2" class="reference"><a href="#cite_note-GH2016-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Robbins9thC6_11-0" class="reference"><a href="#cite_note-Robbins9thC6-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p><p>Svaka T-ćelija ima različit <a href="/w/index.php?title=Receptor_T-%C4%87elija&action=edit&redlink=1" class="new" title="Receptor T-ćelija (stranica ne postoji)">receptor T-ćelija</a>, prilagođen određenoj supstanci, koja se naziva <a href="/wiki/Antigen" title="Antigen">antigen</a>.<sup id="cite_ref-Robbins9thC6_11-1" class="reference"><a href="#cite_note-Robbins9thC6-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Većina receptora T-ćelija veže se za <a href="/wiki/Glavni_kompleks_histokompatibilnosti" title="Glavni kompleks histokompatibilnosti">glavni kompleks histokompatibilnosti</a>, na ćelijama tijela. MHC predstavlja antigen za receptor za T-ćelije, koji postaje aktivan ako se podudara sa određenim receptorima za T-ćeliju.<sup id="cite_ref-Robbins9thC6_11-2" class="reference"><a href="#cite_note-Robbins9thC6-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Da bi bila ispravno funkcionalna, zrela T-ćelija mora se moći vezati za molekule <a href="/wiki/MHC" class="mw-redirect" title="MHC">MHC</a> ("pozitivna selekcija"), a ne da reaguje protiv antigena koji su zapravo iz tjelesnih tkiva ("negativna selekcija").<sup id="cite_ref-Robbins9thC6_11-3" class="reference"><a href="#cite_note-Robbins9thC6-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Pozitivna selekcija se događa u kori, a negativna u srži timusa.<sup id="cite_ref-MDB2019_12-0" class="reference"><a href="#cite_note-MDB2019-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> Nakon ovog procesa, preživjele T-ćelije napuštaju timus, što je regulirano <a href="/w/index.php?title=Sfingozin-1-fosfat&action=edit&redlink=1" class="new" title="Sfingozin-1-fosfat (stranica ne postoji)">sfingozin-1-fosfatom</a>.<sup id="cite_ref-MDB2019_12-1" class="reference"><a href="#cite_note-MDB2019-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> Dalje sazrijevanje događa se u perifernoj cirkulaciji.<sup id="cite_ref-MDB2019_12-2" class="reference"><a href="#cite_note-MDB2019-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> Nešto od toga je zbog hormona i <a href="/wiki/Citokin" title="Citokin">citokina</a> koje luče ćelije unutar timusa, uključujući <a href="/wiki/Timulin" title="Timulin">timulin</a>, <a href="/wiki/Timopoetin" title="Timopoetin">timopoetin</a> i <a href="/wiki/Timozin" title="Timozin">timozine</a>.<sup id="cite_ref-Wheaters2013_7-7" class="reference"><a href="#cite_note-Wheaters2013-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Pozitivna_selekcija">Pozitivna selekcija</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=9" title="Uredi odlomak "Pozitivna selekcija"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=9" title="Edit section's source code: Pozitivna selekcija"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>T-ćelije imaju svoje različite receptore. Ovi različiti receptori nastaju procesom preuređenja gena <a href="/w/index.php?title=V_(D)_J&action=edit&redlink=1" class="new" title="V (D) J (stranica ne postoji)">V (D) J</a>, stimuliranim genima <a href="/wiki/RAG1" title="RAG1">RAG1</a> i <a href="/wiki/RAG2" title="RAG2">RAG2</a>.<sup id="cite_ref-MDB2019_12-3" class="reference"><a href="#cite_note-MDB2019-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> Ovaj proces je podložan greškama, a neki timociti ne uspijevaju stvoriti funkcionalne receptore za T-ćelije, dok drugi stvaraju receptore za T-ćelije koji su autoreaktivni. Ako se formira funkcionalni receptor za T-ćelije, timocit će početi istodobno eksprimirati proteine <a href="/w/index.php?title=CD4&action=edit&redlink=1" class="new" title="CD4 (stranica ne postoji)">CD4</a> i <a href="/w/index.php?title=CD8&action=edit&redlink=1" class="new" title="CD8 (stranica ne postoji)">CD8</a> na površini ćelije. </p><p>Preživljavanje i priroda T-ćelije tada ovisi o njenoj interakciji s okolnim epitelnim ćelijama timusa. Ovdje receptor za T-ćeliju stupa u interakciju s molekulama MHC na površini epitelnih ćelija. T-ćelija s receptorom koji ne reagira ili slabo reagira umrijet će od <a href="/wiki/Apoptoza" title="Apoptoza">apoptoze</a>. AT-ćelija koja reagira preživjet će i razmnožiti se. Zrela T-ćelija izražava samo CD4 ili CD8, ali ne i oba. To ovisi o snazi vezanja između TCR i MHC klase 1 ili klase 2. Receptor AT-ćelije, koji se veže uglavnom za MHC klase I, teži stvaranju zrelih "citotoksičnih" CD8 pozitivnih T-ćelija; receptor za T ćelije koji se uglavnom veže za MHC klase II teži stvaranju CD4 pozitivnih T-ćelija. < </p> <div class="mw-heading mw-heading3"><h3 id="Negativna_selekcija">Negativna selekcija</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=10" title="Uredi odlomak "Negativna selekcija"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=10" title="Edit section's source code: Negativna selekcija"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>T-ćelije koje napadaju vlastite proteine u tijelu eliminiraju se u timusu, što se naziva "negativna selekcija".<sup id="cite_ref-Robbins9thC6_11-4" class="reference"><a href="#cite_note-Robbins9thC6-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Epitelne ćelije u srži i dendritne ćelije u timusu izražavaju glavne proteine iz drugih dijelova tijela. Gen koji to stimulirfa je <a href="/wiki/AIRE" title="AIRE">AIRE</a>.<sup id="cite_ref-Robbins9thC6_11-5" class="reference"><a href="#cite_note-Robbins9thC6-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Timociti koji snažno reagiraju na sopstvene antigene ne opstaju i umiru apoptozom.<sup id="cite_ref-Robbins9thC6_11-6" class="reference"><a href="#cite_note-Robbins9thC6-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> Neke CD4 pozitivne T-ćelije izložene samoantigenima opstaju kao <a href="/w/index.php?title=T-regulacijska_%C4%87elija&action=edit&redlink=1" class="new" title="T-regulacijska ćelija (stranica ne postoji)">T-regulacijske ćelije</a>.<sup id="cite_ref-Robbins9thC6_11-7" class="reference"><a href="#cite_note-Robbins9thC6-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Klinički_značaj"><span id="Klini.C4.8Dki_zna.C4.8Daj"></span>Klinički značaj</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=11" title="Uredi odlomak "Klinički značaj"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=11" title="Edit section's source code: Klinički značaj"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Imunodeficijencija">Imunodeficijencija</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=12" title="Uredi odlomak "Imunodeficijencija"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=12" title="Edit section's source code: Imunodeficijencija"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Kako se u timusu razvijaju T-ćelije, urođeni problemi s razvojem timusa mogu dovesti do <a href="/wiki/Imunodeficijencija" title="Imunodeficijencija">imunodeficijencije</a>, bilo zbog problema s razvojem timusne žlijezde, bilo zbog problema specifičnog za razvoj timocita. Imunodeficijencija može biti duboka. <sup id="cite_ref-FOOTNOTEDavidsonova201867_13-0" class="reference"><a href="#cite_note-FOOTNOTEDavidsonova201867-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> Gubitak timusa u ranoj dobi genetičkom mutacijom (kao u <a href="/wiki/DiGeorgeov_sindrom" title="DiGeorgeov sindrom">DiGeorgeovom</a>, <a href="/w/index.php?title=CHARGE_sindrom&action=edit&redlink=1" class="new" title="CHARGE sindrom (stranica ne postoji)">CHARGE sindromu</a> ili vrlo rijetko "goli" timus koji uzrokuje odsustvo dlaka i timusa <sup id="cite_ref-FOOTNOTEHarrison's20152493_14-0" class="reference"><a href="#cite_note-FOOTNOTEHarrison's20152493-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup>) rezultira ozbiljnom imunodeficijencijom i posljedičnom velikom podložnošću infekciji virusima, <a href="/wiki/Protozoa" title="Protozoa">protozoama</a> i <a href="/wiki/Gljiva" class="mw-redirect" title="Gljiva">gljivama</a>. <sup id="cite_ref-FOOTNOTEDavidsonova201879–80_15-0" class="reference"><a href="#cite_note-FOOTNOTEDavidsonova201879–80-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> <a href="/w/index.php?title=Goli_mi%C5%A1&action=edit&redlink=1" class="new" title="Goli miš (stranica ne postoji)">Goli miševi</a> sa vrlo rijetkim "golišavim" nedostatkom kao rezultat mutacije <a href="/w/index.php?title=FOXN1&action=edit&redlink=1" class="new" title="FOXN1 (stranica ne postoji)">FOXN1</a> soj su istraživačkih miševa kao modela nedostatka T-ćelija.<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> </p><p>Najčešći urođeni uzrok imunske insuficijencije povezane s timusom rezultat je delecije <a href="/wiki/Hromosom_22_(%C4%8Dovjek)" class="mw-redirect" title="Hromosom 22 (čovjek)">22. hromosoma</a>, zvane <a href="/wiki/DiGeorgeov_sindrom" title="DiGeorgeov sindrom">DiGeorgeov sindrom</a>. <sup id="cite_ref-FOOTNOTEHarrison's20152493_14-1" class="reference"><a href="#cite_note-FOOTNOTEHarrison's20152493-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> <sup id="cite_ref-FOOTNOTEDavidsonova201879–80_15-1" class="reference"><a href="#cite_note-FOOTNOTEDavidsonova201879–80-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> To rezultira neuspjehom u razvoju treće i četvrte ždrijelne vrećice i neuspjehom u razvoju timusa i promjenjivim drugim povezanim problemima, kao što su <a href="/w/index.php?title=Kongenitalna_bolest_srca&action=edit&redlink=1" class="new" title="Kongenitalna bolest srca (stranica ne postoji)">kongenitalna bolest srca</a> i abnormalnosti usta (kao što su <a href="/wiki/Rascjep_nepca" class="mw-redirect" title="Rascjep nepca">rascjep nepca</a> i <a href="/wiki/Rascjep_usne" class="mw-redirect" title="Rascjep usne">rascjep usne</a>), neuspjeh u razvoju <a href="/wiki/Paratiroidne_%C5%BElijezde" class="mw-redirect" title="Paratiroidne žlijezde">paratiroidnih žlijezda</a> i prisustvo fistule između <a href="/wiki/Du%C5%A1nik" title="Dušnik">dušnika</a> i <a href="/wiki/Jednjak" title="Jednjak">jednjaka</a>. <sup id="cite_ref-FOOTNOTEDavidsonova201879–80_15-2" class="reference"><a href="#cite_note-FOOTNOTEDavidsonova201879–80-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> Primjećen je vrlo mali broj T-ćelija u cirkulaciji. <sup id="cite_ref-FOOTNOTEDavidsonova201879–80_15-3" class="reference"><a href="#cite_note-FOOTNOTEDavidsonova201879–80-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> Stanje se dijagnosticira <a href="/wiki/FISH" class="mw-redirect" title="FISH">fluorescentnom <i>in situ</i> hibridizacijom</a> i liječi se <a href="/w/index.php?title=Transplantacija_timusa&action=edit&redlink=1" class="new" title="Transplantacija timusa (stranica ne postoji)">transplantacijom timusa</a>.<sup id="cite_ref-FOOTNOTEHarrison's20152493_14-2" class="reference"><a href="#cite_note-FOOTNOTEHarrison's20152493-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> </p><p><a href="/wiki/SCID" class="mw-redirect" title="SCID">Teška kombinirana imunodeficijencija</a> (SCID) su skupina rijetkih urođenih genetičkih bolesti koje mogu rezultirati kombiniranim nedostacima T-, B- i <a href="/wiki/NK-%C4%87elija" class="mw-redirect" title="NK-ćelija">NK-ćelija</a>. Ovi sindromi su uzrokovani mutacijama koje utiču na sazrijevanje <a href="/w/index.php?title=Hematopoetski_progenitorne_%C4%87elije&action=edit&redlink=1" class="new" title="Hematopoetski progenitorne ćelije (stranica ne postoji)">hemmatopoetski programiranih ćelija</a>, koje su preteče i B- i <a href="/wiki/T-%C4%87elija" title="T-ćelija">T-ćelija</a>.<sup id="cite_ref-FOOTNOTEDavidson's201879–80_17-0" class="reference"><a href="#cite_note-FOOTNOTEDavidson's201879–80-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> Broj genetički defekti mogu prouzrokovati SCID, uključujući gubitak funkcije gena <a href="/w/index.php?title=IL-2_receptor&action=edit&redlink=1" class="new" title="IL-2 receptor (stranica ne postoji)">IL-2 receptora</a> i mutaciju koja rezultira nedostatkom <a href="/wiki/Enzim" title="Enzim">enzima</a> <a href="/w/index.php?title=Adenin-deaminaza&action=edit&redlink=1" class="new" title="Adenin-deaminaza (stranica ne postoji)">adenin-deaminaza</a>.<sup id="cite_ref-FOOTNOTEDavidson's201879–80_17-1" class="reference"><a href="#cite_note-FOOTNOTEDavidson's201879–80-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Historija">Historija</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=13" title="Uredi odlomak "Historija"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=13" title="Edit section's source code: Historija"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Timus je bio poznat <a href="/wiki/Anti%C4%8Dka_Gr%C4%8Dka" title="Antička Grčka">drevnim Grcima</a>, a njegovo ime dolazi od grčke riječi θυμός – <i>thumos</i> = ljutnja ili srce, duša, želja, život, vjerovatno zbog svoje mjesto u grudima, blizu mjesta gdje se subjektivno osjećaju emocije;<sup id="cite_ref-18" class="reference"><a href="#cite_note-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> ili pak ime potiče od biljke <i><a href="/w/index.php?title=Timijan&action=edit&redlink=1" class="new" title="Timijan (stranica ne postoji)">timijan</a></i> (također na grčkom <i> θύμος </i> ili <i> θυμάρι </i>), koja je postala naziv za "bradavičasto ispuštanje", moguće zbog sličnosti s gomilom timijana.<sup id="cite_ref-19" class="reference"><a href="#cite_note-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> </p><p><a href="/wiki/Galen" title="Galen">Galen</a> je prvi primijetio da se veličina organa mijenjala tokom trajanja čovjekova života.<sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Dodatne_slike">Dodatne slike</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=14" title="Uredi odlomak "Dodatne slike"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=14" title="Edit section's source code: Dodatne slike"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul class="gallery mw-gallery-traditional"> <li class="gallerybox" style="width: 155px"> <div class="thumb" style="width: 150px; height: 150px;"><span typeof="mw:File"><a href="/wiki/Datoteka:Radiology_1300566_Nevit.jpg" class="mw-file-description" title="Fetusni timus: Na rendgenskom snimku grudnog koša timus se pojavljuje kao radiogusta nakupina (sjajnija na ovoj slici), masa uz gornji režanj desnog (lijevog na slici) plućnog krila djeteta."><img alt="Fetusni timus: Na rendgenskom snimku grudnog koša timus se pojavljuje kao radiogusta nakupina (sjajnija na ovoj slici), masa uz gornji režanj desnog (lijevog na slici) plućnog krila djeteta." src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/Radiology_1300566_Nevit.jpg/120px-Radiology_1300566_Nevit.jpg" decoding="async" width="120" height="90" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/Radiology_1300566_Nevit.jpg/180px-Radiology_1300566_Nevit.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/Radiology_1300566_Nevit.jpg/240px-Radiology_1300566_Nevit.jpg 2x" data-file-width="3072" data-file-height="2304" /></a></span></div> <div class="gallerytext"><a href="/wiki/Fetus" title="Fetus">Fetusni</a> timus: Na rendgenskom snimku grudnog koša timus se pojavljuje kao radiogusta nakupina (sjajnija na ovoj slici), masa uz gornji režanj desnog (lijevog na slici) plućnog krila djeteta.</div> </li> <li class="gallerybox" style="width: 155px"> <div class="thumb" style="width: 150px; height: 150px;"><span typeof="mw:File"><a href="/wiki/Datoteka:Thoracic_cavity_of_foetus_2.JPG" class="mw-file-description" title="Grudni koš fetusa"><img alt="Grudni koš fetusa" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/42/Thoracic_cavity_of_foetus_2.JPG/120px-Thoracic_cavity_of_foetus_2.JPG" decoding="async" width="120" height="90" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/42/Thoracic_cavity_of_foetus_2.JPG/180px-Thoracic_cavity_of_foetus_2.JPG 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/42/Thoracic_cavity_of_foetus_2.JPG/240px-Thoracic_cavity_of_foetus_2.JPG 2x" data-file-width="960" data-file-height="720" /></a></span></div> <div class="gallerytext">Grudni koš fetusa</div> </li> </ul> <div class="mw-heading mw-heading2"><h2 id="Reference">Reference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=15" title="Uredi odlomak "Reference"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=15" title="Edit section's source code: Reference"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><i>Ovaj članak sadrži tekst u <a href="/wiki/Javno_vlasni%C5%A1tvo" title="Javno vlasništvo">javnom vlasništvu</a> sa <a rel="nofollow" class="external text" href="https://archive.org/stream/anatomyofhumanbo1918gray#page/1273/mode/2up">stranice 1273</a>  20. izdanja </i> <a href="/w/index.php?title=Grayeva_anatomija&action=edit&redlink=1" class="new" title="Grayeva anatomija (stranica ne postoji)">Grayeve anatomije</a> <i>(1918)</i> </p> <style data-mw-deduplicate="TemplateStyles:r3312388">.mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-Greys2008-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-Greys2008_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Greys2008_1-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text">Standring S, et al., eds. (2008). Gray's Anatomy: The Anatomical Basis of Clinical Practice (40th ed.). London: Churchill Livingstone. <a href="/wiki/Posebno:Knji%C5%BEni_izvori/9780808923718" class="internal mw-magiclink-isbn">ISBN 978-0-8089-2371-8</a>.</span> </li> <li id="cite_note-Greys2016-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-Greys2016_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Greys2016_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Greys2016_2-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-Greys2016_2-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-Greys2016_2-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-Greys2016_2-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-Greys2016_2-6"><sup><i><b>g</b></i></sup></a> <a href="#cite_ref-Greys2016_2-7"><sup><i><b>h</b></i></sup></a> <a href="#cite_ref-Greys2016_2-8"><sup><i><b>i</b></i></sup></a> <a href="#cite_ref-Greys2016_2-9"><sup><i><b>j</b></i></sup></a> <a href="#cite_ref-Greys2016_2-10"><sup><i><b>k</b></i></sup></a> <a href="#cite_ref-Greys2016_2-11"><sup><i><b>l</b></i></sup></a></span> <span class="reference-text">Standring S, Gray H, eds. (2016). Gray's Anatomy: The Anatomical Basis of Clinical Practice (41st ed.). Philadelphia. pp. 983–6. <a href="/wiki/Posebno:Knji%C5%BEni_izvori/9780702052309" class="internal mw-magiclink-isbn">ISBN 9780702052309</a>. OCLC 920806541.</span> </li> <li id="cite_note-Grays2008-3"><span class="mw-cite-backlink">^ <a href="#cite_ref-Grays2008_3-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Grays2008_3-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r3303350">.mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .id-lock-free a,.mw-parser-output .citation .cs1-lock-free a{background:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited a,.mw-parser-output .id-lock-registration a,.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription a,.mw-parser-output .citation .cs1-lock-subscription a{background:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-ws-icon a{background:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-maint{display:none;color:#33aa33;margin-left:0.3em}.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}</style><cite id="CITEREFStandringBorley2008" class="citation book cs1">Standring, Susan; et al., ured. (2008). <i>Gray's Anatomy: The Anatomical Basis of Clinical Practice</i> (40th izd.). London: Churchill Livingstone. <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/978-0-8089-2371-8" title="Posebno:Knjižni izvori/978-0-8089-2371-8"><bdi>978-0-8089-2371-8</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Gray%27s+Anatomy%3A+The+Anatomical+Basis+of+Clinical+Practice&rft.place=London&rft.edition=40th&rft.pub=Churchill+Livingstone&rft.date=2008&rft.isbn=978-0-8089-2371-8&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-Robbins9th-4"><span class="mw-cite-backlink">^ <a href="#cite_ref-Robbins9th_4-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Robbins9th_4-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Robbins9th_4-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-Robbins9th_4-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-Robbins9th_4-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-Robbins9th_4-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-Robbins9th_4-6"><sup><i><b>g</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFKumarAbbasFaustoAster2014" class="citation book cs1">Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon C. (27. 8. 2014). "Chapter 13. Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus: Thymus.". <i>Robbins and Cotran Pathologic Basis of Disease</i> (9th (online) izd.). <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/9780323296397" title="Posebno:Knjižni izvori/9780323296397"><bdi>9780323296397</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Chapter+13.+Diseases+of+White+Blood+Cells%2C+Lymph+Nodes%2C+Spleen%2C+and+Thymus%3A+Thymus.&rft.btitle=Robbins+and+Cotran+Pathologic+Basis+of+Disease&rft.edition=9th+%28online%29&rft.date=2014-08-27&rft.isbn=9780323296397&rft.aulast=Kumar&rft.aufirst=Vinay&rft.au=Abbas%2C+Abul+K.&rft.au=Fausto%2C+Nelson&rft.au=Aster%2C+Jon+C.&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-Grays2016-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-Grays2016_5-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFStandringGray2016" class="citation book cs1">Standring, Susan; Gray, Henry, ured. (2016). <i>Gray's Anatomy: The Anatomical Basis of Clinical Practice</i> (41st izd.). Philadelphia. str. 983–6. <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/9780702052309" title="Posebno:Knjižni izvori/9780702052309"><bdi>9780702052309</bdi></a>. <a href="/wiki/OCLC_(identifikator)" class="mw-redirect" title="OCLC (identifikator)">OCLC</a> <a rel="nofollow" class="external text" href="//www.worldcat.org/oclc/920806541">920806541</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Gray%27s+Anatomy%3A+The+Anatomical+Basis+of+Clinical+Practice&rft.place=Philadelphia&rft.pages=983-6&rft.edition=41st&rft.date=2016&rft_id=info%3Aoclcnum%2F920806541&rft.isbn=9780702052309&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFLarsen2001" class="citation book cs1">Larsen W (2001). <i>Human Embryology</i> (3rd izd.). Elsevier. str. 366–367. <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/978-0-443-06583-5" title="Posebno:Knjižni izvori/978-0-443-06583-5"><bdi>978-0-443-06583-5</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Human+Embryology&rft.pages=366-367&rft.edition=3rd&rft.pub=Elsevier&rft.date=2001&rft.isbn=978-0-443-06583-5&rft.aulast=Larsen&rft.aufirst=W&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-Wheaters2013-7"><span class="mw-cite-backlink">^ <a href="#cite_ref-Wheaters2013_7-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Wheaters2013_7-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Wheaters2013_7-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-Wheaters2013_7-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-Wheaters2013_7-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-Wheaters2013_7-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-Wheaters2013_7-6"><sup><i><b>g</b></i></sup></a> <a href="#cite_ref-Wheaters2013_7-7"><sup><i><b>h</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFYoungO'DowdWoodford2013" class="citation book cs1">Young, Barbara; O'Dowd, Geraldine; Woodford, Phillip (2013). <i>Wheater's functional histology: a text and colour atlas</i> (6th izd.). Philadelphia: Elsevier. str. 204–6. <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/9780702047473" title="Posebno:Knjižni izvori/9780702047473"><bdi>9780702047473</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Wheater%27s+functional+histology%3A+a+text+and+colour+atlas.&rft.place=Philadelphia&rft.pages=204-6&rft.edition=6th&rft.pub=Elsevier&rft.date=2013&rft.isbn=9780702047473&rft.aulast=Young&rft.aufirst=Barbara&rft.au=O%27Dowd%2C+Geraldine&rft.au=Woodford%2C+Phillip&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFVenturiVenturi2009" class="citation journal cs1">Venturi S, Venturi M (septembar 2009). "Iodine, thymus, and immunity". <i>Nutrition</i>. <b>25</b> (9): 977–9. <a href="/wiki/Doi_(identifikator)" class="mw-redirect" title="Doi (identifikator)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.nut.2009.06.002">10.1016/j.nut.2009.06.002</a>. <a href="/wiki/PMID_(identifikator)" class="mw-redirect" title="PMID (identifikator)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/19647627">19647627</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nutrition&rft.atitle=Iodine%2C+thymus%2C+and+immunity&rft.volume=25&rft.issue=9&rft.pages=977-9&rft.date=2009-09&rft_id=info%3Adoi%2F10.1016%2Fj.nut.2009.06.002&rft_id=info%3Apmid%2F19647627&rft.aulast=Venturi&rft.aufirst=S&rft.au=Venturi%2C+M&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-9">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFSutherlandGoldbergHammettUldrich2005" class="citation journal cs1">Sutherland JS, Goldberg GL, Hammett MV, Uldrich AP, Berzins SP, Heng TS, et al. (august 2005). <a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.175.4.2741">"Activation of thymic regeneration in mice and humans following androgen blockade"</a>. <i>Journal of Immunology</i>. <b>175</b> (4): 2741–53. <a href="/wiki/Doi_(identifikator)" class="mw-redirect" title="Doi (identifikator)">doi</a>:<span class="cs1-lock-free" title="Slobodno dostupno"><a rel="nofollow" class="external text" href="https://doi.org/10.4049%2Fjimmunol.175.4.2741">10.4049/jimmunol.175.4.2741</a></span>. <a href="/wiki/PMID_(identifikator)" class="mw-redirect" title="PMID (identifikator)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/16081852">16081852</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Immunology&rft.atitle=Activation+of+thymic+regeneration+in+mice+and+humans+following+androgen+blockade&rft.volume=175&rft.issue=4&rft.pages=2741-53&rft.date=2005-08&rft_id=info%3Adoi%2F10.4049%2Fjimmunol.175.4.2741&rft_id=info%3Apmid%2F16081852&rft.aulast=Sutherland&rft.aufirst=JS&rft.au=Goldberg%2C+GL&rft.au=Hammett%2C+MV&rft.au=Uldrich%2C+AP&rft.au=Berzins%2C+SP&rft.au=Heng%2C+TS&rft.au=Blazar%2C+BR&rft.au=Millar%2C+JL&rft.au=Malin%2C+MA&rft.au=Chidgey%2C+AP&rft.au=Boyd%2C+RL&rft_id=%2F%2Fdoi.org%2F10.4049%252Fjimmunol.175.4.2741&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-GH2016-10"><span class="mw-cite-backlink">^ <a href="#cite_ref-GH2016_10-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-GH2016_10-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-GH2016_10-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFHall2016" class="citation book cs1">Hall, John E. (2016). <a rel="nofollow" class="external text" href="https://archive.org/details/guytonhalltextbo0000hall"><i>Guyton and Hall textbook of medical physiology</i></a> (13th izd.). Philadelphia: Elsevier. str. <a rel="nofollow" class="external text" href="https://archive.org/details/guytonhalltextbo0000hall/page/466">466</a>–7. <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/978-1-4557-7016-8" title="Posebno:Knjižni izvori/978-1-4557-7016-8"><bdi>978-1-4557-7016-8</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Guyton+and+Hall+textbook+of+medical+physiology&rft.place=Philadelphia&rft.pages=466-7&rft.edition=13th&rft.pub=Elsevier&rft.date=2016&rft.isbn=978-1-4557-7016-8&rft.aulast=Hall&rft.aufirst=John+E.&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fguytonhalltextbo0000hall&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-Robbins9thC6-11"><span class="mw-cite-backlink">^ <a href="#cite_ref-Robbins9thC6_11-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Robbins9thC6_11-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Robbins9thC6_11-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-Robbins9thC6_11-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-Robbins9thC6_11-4"><sup><i><b>e</b></i></sup></a> <a href="#cite_ref-Robbins9thC6_11-5"><sup><i><b>f</b></i></sup></a> <a href="#cite_ref-Robbins9thC6_11-6"><sup><i><b>g</b></i></sup></a> <a href="#cite_ref-Robbins9thC6_11-7"><sup><i><b>h</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFKumarAbbasFaustoAster2014" class="citation book cs1">Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon C. (27. 8. 2014). "Chapter 6. Diseases of the immune system. The normal immune system.". <i>Robbins and Cotran Pathologic Basis of Disease</i> (9th (online) izd.). <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/9780323296397" title="Posebno:Knjižni izvori/9780323296397"><bdi>9780323296397</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=Chapter+6.+Diseases+of+the+immune+system.+The+normal+immune+system.&rft.btitle=Robbins+and+Cotran+Pathologic+Basis+of+Disease&rft.edition=9th+%28online%29&rft.date=2014-08-27&rft.isbn=9780323296397&rft.aulast=Kumar&rft.aufirst=Vinay&rft.au=Abbas%2C+Abul+K.&rft.au=Fausto%2C+Nelson&rft.au=Aster%2C+Jon+C.&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-MDB2019-12"><span class="mw-cite-backlink">^ <a href="#cite_ref-MDB2019_12-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-MDB2019_12-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-MDB2019_12-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-MDB2019_12-3"><sup><i><b>d</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFHohl2019" class="citation book cs1">Hohl TM (2019). "6. Cell mediated defence against infection: Thymic selection of CD4+ and CD8+ T Cells". u Bennett JE, Dolin R, Blaser MJ (ured.). <i>Mandell, Douglas, and Bennett's principles and practice of infectious diseases</i> (9th (online) izd.). Elsevier. <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/9780323482554" title="Posebno:Knjižni izvori/9780323482554"><bdi>9780323482554</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=bookitem&rft.atitle=6.+Cell+mediated+defence+against+infection%3A+Thymic+selection+of+CD4%2B+and+CD8%2B+T+Cells&rft.btitle=Mandell%2C+Douglas%2C+and+Bennett%27s+principles+and+practice+of+infectious+diseases&rft.edition=9th+%28online%29&rft.pub=Elsevier&rft.date=2019&rft.isbn=9780323482554&rft.aulast=Hohl&rft.aufirst=Tobias+M.&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-FOOTNOTEDavidsonova201867-13"><span class="mw-cite-backlink"><b><a href="#cite_ref-FOOTNOTEDavidsonova201867_13-0">^</a></b></span> <span class="reference-text"><a href="#CITEREFDavidsonova2018">Davidsonova 2018</a>, str. 67.<span class="error harv-error" style="display: none; font-size:100%"> harv error: no target: CITEREFDavidsonova2018 (<a href="/wiki/Kategorija:Harv_and_Sfn_template_errors" title="Kategorija:Harv and Sfn template errors">help</a>)</span></span> </li> <li id="cite_note-FOOTNOTEHarrison's20152493-14"><span class="mw-cite-backlink">^ <a href="#cite_ref-FOOTNOTEHarrison's20152493_14-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-FOOTNOTEHarrison's20152493_14-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-FOOTNOTEHarrison's20152493_14-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a href="#CITEREFHarrison's2015">Harrison's 2015</a>, str. 2493.</span> </li> <li id="cite_note-FOOTNOTEDavidsonova201879–80-15"><span class="mw-cite-backlink">^ <a href="#cite_ref-FOOTNOTEDavidsonova201879–80_15-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-FOOTNOTEDavidsonova201879–80_15-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-FOOTNOTEDavidsonova201879–80_15-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-FOOTNOTEDavidsonova201879–80_15-3"><sup><i><b>d</b></i></sup></a></span> <span class="reference-text"><a href="#CITEREFDavidsonova2018">Davidsonova 2018</a>, str. 79–80.<span class="error harv-error" style="display: none; font-size:100%"> harv error: no target: CITEREFDavidsonova2018 (<a href="/wiki/Kategorija:Harv_and_Sfn_template_errors" title="Kategorija:Harv and Sfn template errors">help</a>)</span></span> </li> <li id="cite_note-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-16">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFFox2006" class="citation book cs1">Fox, James G. (2006). <a rel="nofollow" class="external text" href="https://books.google.com/books?id=63K0IifQIrgC&pg=PA277"><i>The Mouse in Biomedical Research: Immunology</i></a> (jezik: engleski). Elsevier. str. 277. <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/978-0-08-046908-9" title="Posebno:Knjižni izvori/978-0-08-046908-9"><bdi>978-0-08-046908-9</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=The+Mouse+in+Biomedical+Research%3A+Immunology&rft.pages=277&rft.pub=Elsevier&rft.date=2006&rft.isbn=978-0-08-046908-9&rft.aulast=Fox&rft.aufirst=James+G.&rft_id=https%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D63K0IifQIrgC%26pg%3DPA277&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-FOOTNOTEDavidson's201879–80-17"><span class="mw-cite-backlink">^ <a href="#cite_ref-FOOTNOTEDavidson's201879–80_17-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-FOOTNOTEDavidson's201879–80_17-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><a href="#CITEREFDavidson's2018">Davidson's 2018</a>, str. 79–80.</span> </li> <li id="cite_note-18"><span class="mw-cite-backlink"><b><a href="#cite_ref-18">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFLiddellScott" class="citation web cs1">Liddell, Henry George; Scott, Robert. <a rel="nofollow" class="external text" href="https://www.perseus.tufts.edu/hopper/text?doc=Perseus:text:1999.04.0057:entry=qumo/s">"θυμός"</a>. <i>A Greek-English Lexicon</i><span class="reference-accessdate">. Pristupljeno 10. 12. 2019</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=A+Greek-English+Lexicon&rft.atitle=%CE%B8%CF%85%CE%BC%CF%8C%CF%82&rft.aulast=Liddell&rft.aufirst=Henry+George&rft.au=Scott%2C+Robert&rft_id=https%3A%2F%2Fwww.perseus.tufts.edu%2Fhopper%2Ftext%3Fdoc%3DPerseus%3Atext%3A1999.04.0057%3Aentry%3Dqumo%2Fs&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-19"><span class="mw-cite-backlink"><b><a href="#cite_ref-19">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.etymonline.com/word/thymus">"thymus | Origin and meaning of thymus by Online Etymology Dictionary"</a>. <i>www.etymonline.com</i> (jezik: engleski)<span class="reference-accessdate">. Pristupljeno 10. 12. 2019</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.etymonline.com&rft.atitle=thymus+%7C+Origin+and+meaning+of+thymus+by+Online+Etymology+Dictionary&rft_id=https%3A%2F%2Fwww.etymonline.com%2Fword%2Fthymus&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> <li id="cite_note-20"><span class="mw-cite-backlink"><b><a href="#cite_ref-20">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFNishinoAshikuKocherThurer2006" class="citation journal cs1">Nishino M, Ashiku SK, Kocher ON, Thurer RL, Boiselle PM, Hatabu H (2006). "The thymus: a comprehensive review". <i>Radiographics</i>. <b>26</b> (2): 335–48. <a href="/wiki/Doi_(identifikator)" class="mw-redirect" title="Doi (identifikator)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1148%2Frg.262045213">10.1148/rg.262045213</a>. <a href="/wiki/PMID_(identifikator)" class="mw-redirect" title="PMID (identifikator)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/16549602">16549602</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Radiographics&rft.atitle=The+thymus%3A+a+comprehensive+review&rft.volume=26&rft.issue=2&rft.pages=335-48&rft.date=2006&rft_id=info%3Adoi%2F10.1148%2Frg.262045213&rft_id=info%3Apmid%2F16549602&rft.aulast=Nishino&rft.aufirst=M&rft.au=Ashiku%2C+SK&rft.au=Kocher%2C+ON&rft.au=Thurer%2C+RL&rft.au=Boiselle%2C+PM&rft.au=Hatabu%2C+H&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Dopunska_literatura">Dopunska literatura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=16" title="Uredi odlomak "Dopunska literatura"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=16" title="Edit section's source code: Dopunska literatura"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r3303351">.mw-parser-output .refbegin{font-size:90%;margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-100{font-size:100%}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}</style><div class="refbegin" style=""> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFDavidson's2018" class="citation book cs1">Ralston, Stuart H.; Penman, Ian D.; Strachan, Mark W.; Hobson, Richard P., ured. (2018). <a rel="nofollow" class="external text" href="https://archive.org/details/davidsonsprincip0000unse_j5e8"><i>Davidson's principles and practice of medicine</i></a> (23rd izd.). Elsevier. <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/978-0-7020-7028-0" title="Posebno:Knjižni izvori/978-0-7020-7028-0"><bdi>978-0-7020-7028-0</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Davidson%27s+principles+and+practice+of+medicine&rft.edition=23rd&rft.pub=Elsevier&rft.date=2018&rft.isbn=978-0-7020-7028-0&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fdavidsonsprincip0000unse_j5e8&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r3303350"><cite id="CITEREFHarrison's2015" class="citation book cs1">Kasper, Dennis; Fauci, Anthony; Hauser, Stephen; Longo, Dan; Jameson, J.; Loscalzo, Joseph (2015). <a rel="nofollow" class="external text" href="https://archive.org/details/isbn_9780071842327"><i>Harrison's Principles of Internal Medicine</i></a> (19th izd.). McGraw-Hill Professional. <a href="/wiki/ISBN_(identifikator)" class="mw-redirect" title="ISBN (identifikator)">ISBN</a> <a href="/wiki/Posebno:Knji%C5%BEni_izvori/9780071802154" title="Posebno:Knjižni izvori/9780071802154"><bdi>9780071802154</bdi></a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Harrison%27s+Principles+of+Internal+Medicine&rft.edition=19th&rft.pub=McGraw-Hill+Professional&rft.date=2015&rft.isbn=9780071802154&rft.aulast=Kasper&rft.aufirst=Dennis&rft.au=Fauci%2C+Anthony&rft.au=Hauser%2C+Stephen&rft.au=Longo%2C+Dan&rft.au=Jameson%2C+J.&rft.au=Loscalzo%2C+Joseph&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fisbn_9780071842327&rfr_id=info%3Asid%2Fbs.wikipedia.org%3ATimus" class="Z3988"></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="Vanjski_linkovi">Vanjski linkovi</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timus&veaction=edit&section=17" title="Uredi odlomak "Vanjski linkovi"" class="mw-editsection-visualeditor"><span>uredi</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timus&action=edit&section=17" title="Edit section's source code: Vanjski linkovi"><span>uredi izvor</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r3627399">.mw-parser-output .side-box{margin:4px 0;box-sizing:border-box;border:1px solid #aaa;font-size:88%;line-height:1.25em;background-color:#f9f9f9;display:flow-root}.mw-parser-output .side-box-abovebelow,.mw-parser-output .side-box-text{padding:0.25em 0.9em}.mw-parser-output .side-box-image{padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .side-box-imageright{padding:2px 0.9em 2px 0;text-align:center}@media(min-width:500px){.mw-parser-output .side-box-flex{display:flex;align-items:center}.mw-parser-output .side-box-text{flex:1;min-width:0}}@media(min-width:720px){.mw-parser-output .side-box{width:238px}.mw-parser-output .side-box-right{clear:right;float:right;margin-left:1em}.mw-parser-output .side-box-left{margin-right:1em}}</style><div class="side-box metadata side-box-right"><style data-mw-deduplicate="TemplateStyles:r3486241">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style> <div class="side-box-flex"> <div class="side-box-image"><figure class="mw-halign-none" typeof="mw:File"><a href="/wiki/Datoteka:Commons-logo.svg" class="mw-file-description" title="Commons logo"><img alt="Commons logo" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png" decoding="async" width="30" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/45px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/60px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a><figcaption>Commons logo</figcaption></figure></div> <div class="side-box-text plainlist"><a href="https://commons.wikimedia.org/wiki/Po%C4%8Detna_strana" class="extiw" title="commons:Početna strana">Commons</a> ima datoteke na temu: <b><span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Category:Thymus_(organ)?uselang=bs">Timus </a></span></b></div></div> </div> <ul><li><a rel="nofollow" class="external text" href="https://www.youtube.com/watch?v=9E_UxnC_L2o">T cell development in the thymus.</a> Video by Janice Yau, describing stromal signaling and tolerance. Department of Immunology and Biomedical Communications, University of Toronto. Masters Research Project, Master of Science in Biomedical Communications. 2011.</li></ul> <div class="noprint portal tleft" style="border:solid #aaa 1px;margin:0.5em 1em 0.5em 0"> <table style="background:#f9f9f9;font-size:85%;line-height:110%;max-width:175px"> <tbody><tr style="vertical-align:middle"><td style="text-align:center"><span class="noviewer" typeof="mw:File"><span><img alt="Portal icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/12px-WHO_Rod.svg.png" decoding="async" width="12" height="28" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/18px-WHO_Rod.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d6/WHO_Rod.svg/24px-WHO_Rod.svg.png 2x" data-file-width="107" data-file-height="250" /></span></span></td><td style="padding:0 0.2em;vertical-align:middle;font-style:italic;font-weight:bold"><a href="/wiki/Portal:Medicina" title="Portal:Medicina">Portal 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class="navbox-group" style="width:1%;background:#E3DAC9;"><a href="/wiki/Ljudski_skelet" class="mw-redirect" title="Ljudski skelet">Skeletni sistem</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Kost" title="Kost">kost</a> <ul><li><a href="/w/index.php?title=Carpus&action=edit&redlink=1" class="new" title="Carpus (stranica ne postoji)">Carpus</a></li> <li><a href="/w/index.php?title=Clavicle&action=edit&redlink=1" class="new" title="Clavicle (stranica ne postoji)">Collar bone</a> (clavicle)</li> <li><a href="/wiki/Femur" class="mw-redirect" title="Femur">Thigh bone</a> (femur)</li> <li><a href="/wiki/Fibula" class="mw-redirect" title="Fibula">Fibula</a></li> <li><a href="/wiki/Humerus" class="mw-redirect" title="Humerus">Humerus</a></li> <li><a href="/w/index.php?title=Human_mandible&action=edit&redlink=1" class="new" title="Human mandible (stranica ne postoji)">Mandible</a></li> <li><a href="/w/index.php?title=Metacarpus&action=edit&redlink=1" class="new" title="Metacarpus (stranica ne postoji)">Metacarpus</a></li> <li><a href="/w/index.php?title=Metatarsus&action=edit&redlink=1" class="new" title="Metatarsus (stranica ne postoji)">Metatarsus</a></li> <li><a href="/w/index.php?title=Ossicles&action=edit&redlink=1" class="new" title="Ossicles (stranica ne postoji)">Ossicles</a></li> <li><a href="/w/index.php?title=Patella&action=edit&redlink=1" class="new" title="Patella (stranica ne postoji)">Patella</a></li> <li><a href="/w/index.php?title=Phalanges&action=edit&redlink=1" class="new" title="Phalanges (stranica ne postoji)">Phalanges</a></li> <li><a href="/w/index.php?title=Radius_(kost)&action=edit&redlink=1" class="new" title="Radius (kost) (stranica ne postoji)">Radius</a></li> <li><a href="/w/index.php?title=Ljudska_lobanja&action=edit&redlink=1" class="new" title="Ljudska lobanja (stranica ne postoji)">lobanja</a> (cranium)</li> <li><a href="/w/index.php?title=Tarsus_(skeleton)&action=edit&redlink=1" class="new" title="Tarsus (skeleton) (stranica ne postoji)">Tarsus</a></li> <li><a href="/w/index.php?title=Tibia&action=edit&redlink=1" class="new" title="Tibia (stranica ne postoji)">Tibia</a></li> <li><a href="/wiki/Ulna" class="mw-redirect" title="Ulna">Ulna</a></li> <li><a href="/w/index.php?title=Rib&action=edit&redlink=1" class="new" title="Rib (stranica ne postoji)">Rib</a></li> <li><a href="/w/index.php?title=Human_vertebra&action=edit&redlink=1" class="new" title="Human vertebra (stranica ne postoji)">Vertebra</a></li> <li><a href="/w/index.php?title=Human_pelvis&action=edit&redlink=1" class="new" title="Human pelvis (stranica ne postoji)">Pelvis</a></li> <li><a href="/w/index.php?title=Human_sternum&action=edit&redlink=1" class="new" title="Human sternum (stranica ne postoji)">Sternum</a></li></ul></li> <li><a href="/w/index.php?title=Cartilage&action=edit&redlink=1" class="new" title="Cartilage (stranica ne postoji)">Cartilage</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background:WhiteSmoke;"><a href="/wiki/Zglob" title="Zglob">zglobovi</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Fibrous_joint&action=edit&redlink=1" class="new" title="Fibrous joint (stranica ne postoji)">Fibrous joint</a></li> <li><a href="/w/index.php?title=Cartilaginous_joint&action=edit&redlink=1" class="new" title="Cartilaginous joint (stranica ne postoji)">Cartilaginous joint</a></li> <li><a href="/w/index.php?title=Synovial_joint&action=edit&redlink=1" class="new" title="Synovial joint (stranica ne postoji)">Synovial joint</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background:Linen;"><a href="/w/index.php?title=Muscular_system&action=edit&redlink=1" class="new" title="Muscular system (stranica ne postoji)">Muscular system</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Muscle&action=edit&redlink=1" class="new" title="Muscle (stranica ne postoji)">Muscle</a></li> <li><a href="/w/index.php?title=Tendon&action=edit&redlink=1" class="new" title="Tendon (stranica ne postoji)">Tendon</a></li> <li><a href="/w/index.php?title=Thoracic_diaphragm&action=edit&redlink=1" class="new" title="Thoracic diaphragm (stranica ne postoji)">Diaphragm</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">TA 5–11:<br /><a href="/w/index.php?title=Splanchnic&action=edit&redlink=1" class="new" title="Splanchnic (stranica ne postoji)">splanchnic</a>/<br /><a href="/w/index.php?title=Viscus&action=edit&redlink=1" class="new" title="Viscus (stranica ne postoji)">viscus</a></th><td class="navbox-list navbox-odd hlist" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">mostly<br /><a href="/w/index.php?title=Thoracic_cavity&action=edit&redlink=1" class="new" title="Thoracic cavity (stranica ne postoji)">Thoracic</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background:MistyRose;"><a href="/w/index.php?title=Respiratory_system&action=edit&redlink=1" class="new" title="Respiratory system (stranica ne postoji)">Respiratory system</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Upper_respiratory_tract&action=edit&redlink=1" class="new" title="Upper respiratory tract (stranica ne postoji)">URT</a> <ul><li><a href="/w/index.php?title=Human_nose&action=edit&redlink=1" class="new" title="Human nose (stranica ne postoji)">Nose</a></li> <li><a href="/w/index.php?title=Nasopharynx&action=edit&redlink=1" class="new" title="Nasopharynx (stranica ne postoji)">Nasopharynx</a></li> <li><a href="/w/index.php?title=Larynx&action=edit&redlink=1" class="new" title="Larynx (stranica ne postoji)">Larynx</a></li></ul></li> <li><a href="/w/index.php?title=Lower_respiratory_tract&action=edit&redlink=1" class="new" title="Lower respiratory tract (stranica ne postoji)">LRT</a> <ul><li><a href="/w/index.php?title=Vertebrate_trachea&action=edit&redlink=1" class="new" title="Vertebrate trachea (stranica ne postoji)">Trachea</a></li> <li><a href="/w/index.php?title=Bronchus&action=edit&redlink=1" class="new" title="Bronchus (stranica ne postoji)">Bronchus</a></li> <li><a href="/w/index.php?title=Human_lung&action=edit&redlink=1" class="new" title="Human lung (stranica ne postoji)">Lung</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">mostly<br /><a href="/w/index.php?title=Abdominopelvic_cavity&action=edit&redlink=1" class="new" title="Abdominopelvic cavity (stranica ne postoji)">Abdominopelvic</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="Digestive_system+adnexa" scope="row" class="navbox-group" style="width:1%;background:#fd6;"><a href="/w/index.php?title=Digestion&action=edit&redlink=1" class="new" title="Digestion (stranica ne postoji)">Digestive system</a>+<br />adnexa</th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Human_mouth&action=edit&redlink=1" class="new" title="Human mouth (stranica ne postoji)">Mouth</a> <ul><li><a href="/w/index.php?title=Salivary_gland&action=edit&redlink=1" class="new" title="Salivary gland (stranica ne postoji)">Salivary gland</a></li> <li><a href="/w/index.php?title=Tongue&action=edit&redlink=1" class="new" title="Tongue (stranica ne postoji)">Tongue</a></li></ul></li> <li><i>upper GI</i> <ul><li><a href="/w/index.php?title=Oropharynx&action=edit&redlink=1" class="new" title="Oropharynx (stranica ne postoji)">Oropharynx</a></li> <li><a href="/w/index.php?title=Laryngopharynx&action=edit&redlink=1" class="new" title="Laryngopharynx (stranica ne postoji)">Laryngopharynx</a></li> <li><a href="/w/index.php?title=Esophagus&action=edit&redlink=1" class="new" title="Esophagus (stranica ne postoji)">Esophagus</a></li> <li><a href="/w/index.php?title=Stomach&action=edit&redlink=1" class="new" title="Stomach (stranica ne postoji)">Stomach</a></li></ul></li> <li><i>lower GI</i> <ul><li><a href="/w/index.php?title=Small_intestine&action=edit&redlink=1" class="new" title="Small intestine (stranica ne postoji)">Small intestine</a></li> <li><a href="/w/index.php?title=Vermiform_appendix&action=edit&redlink=1" class="new" title="Vermiform appendix (stranica ne postoji)">Appendix</a></li> <li><a href="/w/index.php?title=Colon_(anatomy)&action=edit&redlink=1" class="new" title="Colon (anatomy) (stranica ne postoji)">Colon</a></li> <li><a href="/w/index.php?title=Rectum&action=edit&redlink=1" class="new" title="Rectum (stranica ne postoji)">Rectum</a></li> <li><a href="/w/index.php?title=Human_anus&action=edit&redlink=1" class="new" title="Human anus (stranica ne postoji)">Anus</a></li></ul></li> <li><i><a href="/w/index.php?title=Accessory_digestive_gland&action=edit&redlink=1" class="new" title="Accessory digestive gland (stranica ne postoji)">accessory</a></i> <ul><li><a href="/w/index.php?title=Liver&action=edit&redlink=1" class="new" title="Liver (stranica ne postoji)">Liver</a></li> <li><a href="/w/index.php?title=Biliary_tract&action=edit&redlink=1" class="new" title="Biliary tract (stranica ne postoji)">Biliary tract</a></li> <li><a href="/w/index.php?title=Pancreas&action=edit&redlink=1" class="new" title="Pancreas (stranica ne postoji)">Pancreas</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background:#BBEEBB;"><a href="/w/index.php?title=Genitourinarni_sistem&action=edit&redlink=1" class="new" title="Genitourinarni sistem (stranica ne postoji)">GU</a>: <a href="/w/index.php?title=Urinary_system&action=edit&redlink=1" class="new" title="Urinary system (stranica ne postoji)">Urinary system</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Kidney&action=edit&redlink=1" class="new" title="Kidney (stranica ne postoji)">Kidney</a></li> <li><a href="/wiki/Ureter" class="mw-redirect" title="Ureter">Ureter</a></li> <li><a href="/w/index.php?title=Urinary_bladder&action=edit&redlink=1" class="new" title="Urinary bladder (stranica ne postoji)">Bladder</a></li> <li><a href="/wiki/Urethra" class="mw-redirect" title="Urethra">Urethra</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background:#BBEEBB;"><a href="/w/index.php?title=Genitourinary_system&action=edit&redlink=1" class="new" title="Genitourinary system (stranica ne postoji)">GU</a>: <a href="/w/index.php?title=Reproductive_system&action=edit&redlink=1" class="new" title="Reproductive system (stranica ne postoji)">Reproductive system</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Female_reproductive_system_(human)&action=edit&redlink=1" class="new" title="Female reproductive system (human) (stranica ne postoji)">Female</a> <ul><li><a href="/wiki/Uterus" class="mw-redirect" title="Uterus">Uterus</a></li> <li><a href="/wiki/Vagina" title="Vagina">Vagina</a></li> <li><a href="/wiki/Vulva" class="mw-redirect" title="Vulva">Vulva</a></li> <li><a href="/w/index.php?title=Ovary&action=edit&redlink=1" class="new" title="Ovary (stranica ne postoji)">Ovary</a></li> <li><a href="/wiki/Placenta" class="mw-redirect" title="Placenta">Placenta</a></li></ul></li> <li><a href="/w/index.php?title=Human_male_reproductive_system&action=edit&redlink=1" class="new" title="Human male reproductive system (stranica ne postoji)">Male</a> <ul><li><a href="/w/index.php?title=Scrotum&action=edit&redlink=1" class="new" title="Scrotum (stranica ne postoji)">Scrotum</a></li> <li><a href="/w/index.php?title=Human_penis&action=edit&redlink=1" class="new" title="Human penis (stranica ne postoji)">Penis</a></li> <li><a href="/wiki/Prostate" class="mw-redirect" title="Prostate">Prostate</a></li> <li><a href="/w/index.php?title=Testicle&action=edit&redlink=1" class="new" title="Testicle (stranica ne postoji)">Testicle</a></li> <li><a href="/w/index.php?title=Seminal_vesicle&action=edit&redlink=1" class="new" title="Seminal vesicle (stranica ne postoji)">Seminal vesicle</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/w/index.php?title=Endocrine_system&action=edit&redlink=1" class="new" title="Endocrine system (stranica ne postoji)">Endocrine system</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Pituitary_gland&action=edit&redlink=1" class="new" title="Pituitary gland (stranica ne postoji)">Pituitary</a></li> <li><a href="/w/index.php?title=Pineal_gland&action=edit&redlink=1" class="new" title="Pineal gland (stranica ne postoji)">Pineal</a></li> <li><a href="/w/index.php?title=Thyroid&action=edit&redlink=1" class="new" title="Thyroid (stranica ne postoji)">Thyroid</a></li> <li><a href="/w/index.php?title=Parathyroid_gland&action=edit&redlink=1" class="new" title="Parathyroid gland (stranica ne postoji)">Parathyroid</a></li> <li><a href="/w/index.php?title=Adrenal_gland&action=edit&redlink=1" class="new" title="Adrenal gland (stranica ne postoji)">Adrenal</a></li> <li><a href="/w/index.php?title=Islets_of_Langerhans&action=edit&redlink=1" class="new" title="Islets of Langerhans (stranica ne postoji)">Islets of Langerhans</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">TA 12–16</th><td class="navbox-list navbox-odd hlist" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background:MistyRose;"><a href="/w/index.php?title=Circulatory_system&action=edit&redlink=1" class="new" title="Circulatory system (stranica ne postoji)">Circulatory system</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background:MistyRose;"><a href="/w/index.php?title=Circulatory_system&action=edit&redlink=1" class="new" title="Circulatory system (stranica ne postoji)">Cardiovascular system</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><i>peripheral</i> <ul><li><a href="/w/index.php?title=Artery&action=edit&redlink=1" class="new" title="Artery (stranica ne postoji)">Artery</a></li> <li><a href="/w/index.php?title=Vein&action=edit&redlink=1" class="new" title="Vein (stranica ne postoji)">Vein</a></li> <li><a href="/w/index.php?title=Lymphatic_vessel&action=edit&redlink=1" class="new" title="Lymphatic vessel (stranica ne postoji)">Lymphatic vessel</a></li></ul></li> <li><a href="/w/index.php?title=Human_heart&action=edit&redlink=1" class="new" title="Human heart (stranica ne postoji)">Heart</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background:MistyRose;;background-color: LightGreen"><a href="/wiki/Limfni_sistem" title="Limfni sistem">Limfni sistem</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><i>primary</i> <ul><li><a href="/w/index.php?title=Bone_marrow&action=edit&redlink=1" class="new" title="Bone marrow (stranica ne postoji)">Bone marrow</a></li> <li><a href="/wiki/Thymus" title="Thymus">Thymus</a></li></ul></li> <li><i>secondary</i> <ul><li><a href="/w/index.php?title=Spleen&action=edit&redlink=1" class="new" title="Spleen (stranica ne postoji)">Spleen</a></li> <li><a href="/w/index.php?title=Lymph_node&action=edit&redlink=1" class="new" title="Lymph node (stranica ne postoji)">Lymph node</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background:LemonChiffon;"><a href="/wiki/Nervni_sistem" title="Nervni sistem">Nervni sistem</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li> <ul><li><a href="/w/index.php?title=Human_brain&action=edit&redlink=1" class="new" title="Human brain (stranica ne postoji)">Brain</a></li> <li><a href="/w/index.php?title=Spinal_cord&action=edit&redlink=1" class="new" title="Spinal cord (stranica ne postoji)">Spinal cord</a></li> <li><a href="/w/index.php?title=Nerve&action=edit&redlink=1" class="new" title="Nerve (stranica ne postoji)">Nerve</a></li></ul></li> <li><a href="/w/index.php?title=Sensory_system&action=edit&redlink=1" class="new" title="Sensory system (stranica ne postoji)">Sensory system</a> <ul><li><a href="/w/index.php?title=Ear&action=edit&redlink=1" class="new" title="Ear (stranica ne postoji)">Ear</a></li> <li><a href="/w/index.php?title=Human_eye&action=edit&redlink=1" class="new" title="Human eye (stranica ne postoji)">Eye</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background:Linen;"><a href="/w/index.php?title=Integumentary_system&action=edit&redlink=1" class="new" title="Integumentary system (stranica ne postoji)">Integumentary system</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Ljudska_ko%C5%BEa&action=edit&redlink=1" class="new" title="Ljudska koža (stranica ne postoji)">Koža</a></li> <li><a href="/w/index.php?title=Subcutaneous_tissue&action=edit&redlink=1" class="new" title="Subcutaneous tissue (stranica ne postoji)">Subcutaneous tissue</a></li> <li><a href="/w/index.php?title=Breast&action=edit&redlink=1" class="new" title="Breast (stranica ne postoji)">Breast</a> <ul><li><a href="/w/index.php?title=Mammary_gland&action=edit&redlink=1" class="new" title="Mammary gland (stranica ne postoji)">Mammary gland</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/w/index.php?title=Blood&action=edit&redlink=1" class="new" title="Blood (stranica ne postoji)">Blood</a><br />(Non-TA)</th><td class="navbox-list navbox-odd hlist" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background:MistyRose;"><a href="/w/index.php?title=Myeloid&action=edit&redlink=1" class="new" title="Myeloid (stranica ne postoji)">Myeloid</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/w/index.php?title=Immune_system&action=edit&redlink=1" class="new" title="Immune system (stranica ne postoji)">Myeloid immune system</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: LightGreen"><a href="/wiki/Limfociti" title="Limfociti">Limfa</a></th><td class="navbox-list navbox-even" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Imuni_sistem" class="mw-redirect" title="Imuni sistem">Lymphoid immune system</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div><a href="/w/index.php?title=%C5%A0ablon:Anatomy_navs&action=edit&redlink=1" class="new" title="Šablon:Anatomy navs 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