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href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%90%D0%BA%D1%86%D0%B8%D1%98%D0%B0_%D0%BF%D1%80%D0%BE%D1%88%D0%B8%D1%80%D0%B8%D0%B2%D0%B0%D1%9A%D0%B0_%D0%BA%D0%BB%D0%B8%D1%86%D0%B0\" title=\"Википедија:Акција проширивања клица\"\u003Eакцији проширивања клица\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E";}}());</script></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Сајт"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Садржај" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" 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href="#Funkcija"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Funkcija</span> </div> </a> <ul id="toc-Funkcija-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Klinički_značaj" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Klinički_značaj"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Klinički značaj</span> </div> </a> <ul id="toc-Klinički_značaj-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Ligandi" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Ligandi"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Ligandi</span> </div> </a> <ul id="toc-Ligandi-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Reference" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Reference"> <div 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screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox"><tbody><tr><th colspan="4" class="infobox-above">Metabotropni glutamatni receptor 1</th></tr><tr><td colspan="4" class="infobox-image"> <span class="mw-image-border" typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:Protein_GRM1_PDB_1ewk.png" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Protein_GRM1_PDB_1ewk.png/250px-Protein_GRM1_PDB_1ewk.png" decoding="async" width="250" height="202" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Protein_GRM1_PDB_1ewk.png/375px-Protein_GRM1_PDB_1ewk.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/f2/Protein_GRM1_PDB_1ewk.png/500px-Protein_GRM1_PDB_1ewk.png 2x" data-file-width="895" data-file-height="724" /></a></span><div class="infobox-caption"><a href="/wiki/Proteinska_banka_podataka" title="Proteinska banka podataka">PDB</a> prikaz baziran na <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1ewk">1ewk</a></span>.</div></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Dostupne strukture</th></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/3KS9">3KS9</a></span></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Identifikatori</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Organizacija_za_ljudski_genom" title="Organizacija za ljudski genom">Simboli</a></th><td colspan="3" class="infobox-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genenames.org/data/hgnc_data.php?hgnc_id=4593">GRM1</a>; GPRC1A; GRM1A; MGLUR1; MGLUR1A; mGlu1</span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Vanjski ID</th><td colspan="3" class="infobox-data" style="background-color: #eee"> <span class="plainlinks"><a href="/wiki/%D0%9C%D0%B5%D0%BD%D0%B4%D0%B5%D0%BB%D0%BE%D0%B2%D1%81%D0%BA%D0%BE_%D0%BD%D0%B0%D1%81%D0%BB%D0%B5%D1%92%D0%B8%D0%B2%D0%B0%D1%9A%D0%B5_%D0%BA%D0%BE%D0%B4_%D1%87%D0%BE%D0%B2%D0%B5%D0%BA%D0%B0" title="Менделовско наслеђивање код човека">OMIM</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=604473">604473 </a></span> <span class="plainlinks"><a href="/wiki/%D0%98%D0%BD%D1%84%D0%BE%D1%80%D0%BC%D0%B0%D1%82%D0%B8%D0%BA%D0%B0_%D0%BC%D0%B8%D1%88%D1%98%D0%B5%D0%B3_%D0%B3%D0%B5%D0%BD%D0%BE%D0%BC%D0%B0" title="Информатика мишјег генома">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:1351338">1351338 </a></span> <span class="plainlinks"><a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=649">649 </a></span> <a href="/wiki/International_Union_of_Basic_and_Clinical_Pharmacology" class="mw-redirect" title="International Union of Basic and Clinical Pharmacology">IUPHAR</a>: <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.iuphar-db.org/DATABASE/ObjectDisplayForward?objectId=289">mGlu<sub>1</sub></a></span> <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=2911">GRM1 Gene</a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <table class="collapsible collapsed" style="border: none; padding: 0; margin: 0; width: 100%; text-align: left"> <tbody><tr style="background-color: #ddd; text-align: center"> <th colspan="2"><a href="/wiki/Ontologija_gena" title="Ontologija gena">Ontologija gena</a></th> </tr> <tr> <th style="background-color: #c3fdb8">Molekularna funkcija</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0004871">aktivnost prenosnika signala</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0004872">receptorska aktivnost</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0004930">aktivnost G-protein spregnutog receptora</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0008066">aktivnost glutamatnog receptora</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0030331">vezivanje estrogenskog receptora</a></span><br /></td> </tr> <tr> <th style="background-color: #c3fdb8">Celularna komponenta</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005634">nukleus</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005792">mikrozom</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005886">ćelijska membrana</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0005887">integralno sa ćelijskom membranom</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0014069">postsinaptička gustina</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0030424">akson</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0042734">presinaptička membrana</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0043197">dendritna osnova</a></span><br /></td> </tr> <tr> <th style="background-color: #c3fdb8">Biološki proces</th> <td style="background-color: #eee"><big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0000186">aktivacija MAPKK aktivnosti</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0000187">aktivacija MAPK aktivnosti</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007186">signalni put G-protein spregnutog receptora</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007268">sinaptička transmisija</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0007626">lokomotorno ponašanje</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0019722">kalcijumom posredovana signalizacija</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0043408">regulacija MAPK kascade</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0051930">regulacija senzorne percepcije bola</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0051966">regulacija sinaptičke transmisije, glutamatergička</a></span><br /> <big>•</big> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&search_constraint=terms&depth=0&query=GO:0071257">celularni respons na električni stimulus</a></span><br /></td> </tr> </tbody></table></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Pregled RNK izražavanja</th></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PBB_GE_GRM1_207299_s_at_tn.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/PBB_GE_GRM1_207299_s_at_tn.png/250px-PBB_GE_GRM1_207299_s_at_tn.png" decoding="async" width="250" height="132" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/8/8a/PBB_GE_GRM1_207299_s_at_tn.png 1.5x" data-file-width="255" data-file-height="135" /></a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PBB_GE_GRM1_210939_s_at_tn.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e6/PBB_GE_GRM1_210939_s_at_tn.png/250px-PBB_GE_GRM1_210939_s_at_tn.png" decoding="async" width="250" height="132" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/e/e6/PBB_GE_GRM1_210939_s_at_tn.png 1.5x" data-file-width="255" data-file-height="135" /></a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PBB_GE_GRM1_210940_s_at_tn.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/9/95/PBB_GE_GRM1_210940_s_at_tn.png/250px-PBB_GE_GRM1_210940_s_at_tn.png" decoding="async" width="250" height="132" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/9/95/PBB_GE_GRM1_210940_s_at_tn.png 1.5x" data-file-width="255" data-file-height="135" /></a></span></td></tr><tr><td colspan="4" class="infobox-full-data" style="background-color: #eee"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.gnf.org/gene/2911/Dodatni">podaci</a></span></td></tr><tr><th colspan="4" class="infobox-header" style="background-color: #ddd">Ortolozi</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Vrsta</th><td class="infobox-data infobox-data-a"> <b>Čovek</b></td><td class="infobox-data infobox-data-b"> <b>Miš</b></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=2911&rn=1">2911</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=14816&rn=1">14816</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/Ensembl" title="Ensembl">Ensembl</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000152822;db=core">ENSG00000152822</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000019828;db=core">ENSMUSG00000019828</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td class="infobox-data infobox-data-a"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/Q13255">Q13255</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/P97772">P97772</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">RefSeq (mRNA)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_000838.3">NM_000838.3</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001114333.2">NM_001114333.2</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">RefSeq (protein)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_000829.2">NP_000829.2</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_001107805.1">NP_001107805.1</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8">Lokacija (UCSC)</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg19&position=chr6:146348782-146758734">Chr 6:<br />146.35 - 146.76 Mb</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm9&position=chr10:10405857-10802154">Chr 10:<br />10.41 - 10.8 Mb</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #c3fdb8"><a href="/wiki/PubMed" title="PubMed">PubMed</a> pretraga</th><td class="infobox-data infobox-data-a"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=2911">[1]</a></span></td><td class="infobox-data infobox-data-b"> <span class="plainlinks" style="white-space: nowrap"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=14816">[2]</a></span></td></tr></tbody></table> <p><b>Metabotropni glutamatni receptor 1</b> (<i><a rel="nofollow" class="external text" href="http://www.genenames.org/data/hgnc_data.php?match=GRM1">GRM1</a></i>) je ljudski <a href="/wiki/%D0%93%D0%B5%D0%BD" title="Ген">gen</a> koji kodira <i>mGluR1</i> protein.<sup id="cite_ref-entrez_1-0" class="reference"><a href="#cite_note-entrez-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid9076744_2-0" class="reference"><a href="#cite_note-pmid9076744-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid9376535_3-0" class="reference"><a href="#cite_note-pmid9376535-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Funkcija">Funkcija</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&veaction=edit&section=1" title="Уредите одељак „Funkcija”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&action=edit&section=1" title="Уреди извор одељка: Funkcija"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>L-<a href="/wiki/Glutamat" class="mw-redirect" title="Glutamat">glutamat</a> je ekscitatorni <a href="/wiki/%D0%9D%D0%B5%D1%83%D1%80%D0%BE%D1%82%D1%80%D0%B0%D0%BD%D1%81%D0%BC%D0%B8%D1%82%D0%B5%D1%80" title="Неуротрансмитер">neurotransmiter</a> u <a href="/wiki/%D0%A6%D0%B5%D0%BD%D1%82%D1%80%D0%B0%D0%BB%D0%BD%D0%B8_%D0%BD%D0%B5%D1%80%D0%B2%D0%BD%D0%B8_%D1%81%D0%B8%D1%81%D1%82%D0%B5%D0%BC" title="Централни нервни систем">centralnom nervom sistemu</a>. On aktivira <a href="/wiki/Ligandom_kontrolisani_jonski_kanal" class="mw-redirect" title="Ligandom kontrolisani jonski kanal">jonotropne</a> i <a href="/wiki/Metabotropni_glutamatni_receptor" title="Metabotropni glutamatni receptor">metabotropne</a> <a href="/wiki/Glutamatni_receptor" title="Glutamatni receptor">glutamatne receptore</a>. Glutamatergična neurotransmisija učestvuje u znatnom broju aspekata normalne moždane funkcije i može da bude poremećena u slučajevima mnogih neuropatoloških oboljenja. Metabotropni glutamatni receptori su familija <a href="/wiki/G_protein_spregnuti_receptor" class="mw-redirect" title="G protein spregnuti receptor">G protein spregnutih receptora</a>, koja se deli u tri grupe na osnovu sekventne homologije, mehanizma prenosa signala, i farmakoloških svojstava. Grupa I obuhvata GRM1 i <a href="/wiki/Metabotropni_glutamatni_receptor_5" title="Metabotropni glutamatni receptor 5">GRM5</a>. Za te receptore je pokazano da aktiviraju <a href="/wiki/Fosfolipaza_C" class="mw-redirect" title="Fosfolipaza C">fosfolipazu C</a>. U grupi II su <a href="/wiki/Metabotropni_glutamatni_receptor_2" title="Metabotropni glutamatni receptor 2">GRM2</a> i <a href="/wiki/Metabotropni_glutamatni_receptor_3" title="Metabotropni glutamatni receptor 3">GRM3</a>, dok su u grupi III <a href="/wiki/Metabotropni_glutamatni_receptor_4" title="Metabotropni glutamatni receptor 4">GRM4</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_6" title="Metabotropni glutamatni receptor 6">GRM6</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_7" title="Metabotropni glutamatni receptor 7">GRM7</a> i <a href="/wiki/Metabotropni_glutamatni_receptor_8" title="Metabotropni glutamatni receptor 8">GRM8</a>. Grupe II i III receptora su vezana za inhibiciju kaskade <a href="/wiki/%D0%A6%D0%B8%D0%BA%D0%BB%D0%B8%D1%87%D0%BD%D0%B8_%D0%B0%D0%B4%D0%B5%D0%BD%D0%BE%D0%B7%D0%B8%D0%BD_%D0%BC%D0%BE%D0%BD%D0%BE%D1%84%D0%BE%D1%81%D1%84%D0%B0%D1%82" title="Циклични аденозин монофосфат">cikličnog AMP</a>, ali se razlikuju u njihovoj specifičnosti za agoniste. <a href="/wiki/Alternativno_splajsovanje" title="Alternativno splajsovanje">Alternativno splajsne</a> varijante GRM1 gena su opisane, ali odgovarajući proteini pune dužine nisu bili određeni.<sup id="cite_ref-entrez_1-1" class="reference"><a href="#cite_note-entrez-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Klinički_značaj"><span id="Klini.C4.8Dki_zna.C4.8Daj"></span>Klinički značaj</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&veaction=edit&section=2" title="Уредите одељак „Klinički značaj”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&action=edit&section=2" title="Уреди извор одељка: Klinički značaj"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Mutacije <i>GRM1</i> gena mogu da doprinesu podložnosti na razvoj <a href="/wiki/%D0%9C%D0%B5%D0%BB%D0%B0%D0%BD%D0%BE%D0%BC" title="Меланом">melanoma</a>.<sup id="cite_ref-pmid17609672_4-0" class="reference"><a href="#cite_note-pmid17609672-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Ligandi">Ligandi</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&veaction=edit&section=3" title="Уредите одељак „Ligandi”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&action=edit&section=3" title="Уреди извор одељка: Ligandi"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Pored ortosternog mesta vezivanja liganda gde se glutamat vezuje, postoje bar još dva <a href="/wiki/Alosterna_regulacija" title="Alosterna regulacija">alosterna</a> mesta vezivanja na mGluR1 receptoru.<sup id="cite_ref-Hemstapat_K,_de_Paulis_T,_Chen_Y,_et_al._2006_616–26_5-0" class="reference"><a href="#cite_note-Hemstapat_K,_de_Paulis_T,_Chen_Y,_et_al._2006_616–26-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> Znatan broj potentnih i specifičnih alosternih liganda – predominantno antagonista/inhibitora je razvijen, mada ortosterni podtip-selektivni ligandi nisu poznati. </p> <ul><li>JNJ-16259685: visoko potentan, selektivan nekompetitivan antagonist<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup></li> <li>R-214,127 i <a href="/wiki/Radioligand" title="Radioligand">[<sup>3</sup>H]</a>-analog: selektivni alosterni inhibitor visokog afiniteta<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup></li> <li>YM-202,074: selektivni alosterni antagonist visokog afiniteta<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup></li> <li>YM-230,888: selektivni alosterni antagonist visokog afiniteta<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup></li> <li>YM-298,198 i [<sup>3</sup>H]-analog: selektivni nekompetitivni antagonist<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup></li> <li>FTIDC: selektivni alosterni antagonist/inverzni agonist visokog afiniteta<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup></li> <li>A-841,720: potentan nekompetitivni antagonist; manje hmGluR5 vezivanje<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup></li> <li>VU-71: potencijator<sup id="cite_ref-Hemstapat_K,_de_Paulis_T,_Chen_Y,_et_al._2006_616–26_5-1" class="reference"><a href="#cite_note-Hemstapat_K,_de_Paulis_T,_Chen_Y,_et_al._2006_616–26-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup></li> <li>Fluorisani oksazol-2-il-amidi 9<i>H</i>-ksanten-9-karboksilne kiseline: oralno dostupni potencijatori<sup id="cite_ref-pmid19233648_13-0" class="reference"><a href="#cite_note-pmid19233648-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup></li></ul> <figure class="mw-halign-left" typeof="mw:File/Thumb"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:Selective_mGluR1_ligands.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/6/67/Selective_mGluR1_ligands.png/600px-Selective_mGluR1_ligands.png" decoding="async" width="600" height="332" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/67/Selective_mGluR1_ligands.png/900px-Selective_mGluR1_ligands.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/67/Selective_mGluR1_ligands.png/1200px-Selective_mGluR1_ligands.png 2x" data-file-width="2932" data-file-height="1622" /></a><figcaption>Hemijska strukture mGluR1 selektivnih liganda.</figcaption></figure><div style="clear:left;"></div> <div class="mw-heading mw-heading2"><h2 id="Reference">Reference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&veaction=edit&section=4" title="Уредите одељак „Reference”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&action=edit&section=4" title="Уреди извор одељка: Reference"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r28440201">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output 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title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3AMetabotropni+glutamatni+receptor+1&rft.atitle=Fluorinated+9H-xanthene-9-carboxylic+acid+oxazol-2-yl-amides+as+potent%2C+orally+available+mGlu1+receptor+enhancers&rft.au=Huwyler%2C+J&rft.au=Jolidon%2C+S&rft.au=Knoflach%2C+F&rft.au=Mutel%2C+V&rft.au=Wichmann%2C+J&rft.aufirst=E&rft.aulast=Vieira&rft.date=2009&rft.genre=article&rft.issue=6&rft.jtitle=Bioorg.+Med.+Chem.+Lett.&rft.pages=1666-9&rft.volume=19&rft_id=info%3Adoi%2F10.1016%2Fj.bmcl.2009.01.108&rft_id=info%3Apmid%2F19233648&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Literatura">Literatura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&veaction=edit&section=5" title="Уредите одељак „Literatura”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&action=edit&section=5" title="Уреди извор одељка: Literatura"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r28440192">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-count references-column-count-2" style="column-count: 2;"> <ul><li><cite class="citation journal">Bockaert J, Pin JP (1999). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1171258">„Molecular tinkering of G protein-coupled receptors: an evolutionary success.”</a>. <i>EMBO J</i>. <b>18</b> (7): 1723—9. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1171258">1171258</a> <span typeof="mw:File"><span title="Слободан приступ"><img alt="Слободан приступ" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" 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Chem</i>. <b>275</b> (44): 34245—51. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/10945991">10945991</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.M005581200">10.1074/jbc.M005581200</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3AMetabotropni+glutamatni+receptor+1&rft.atitle=Cys-140+is+critical+for+metabotropic+glutamate+receptor-1+dimerization&rft.au=Hauschild%2C+BC&rft.aufirst=K&rft.aulast=Ray&rft.date=2000&rft.genre=article&rft.issue=44&rft.jtitle=J.+Biol.+Chem.&rft.pages=34245-51&rft.volume=275&rft_id=info%3Adoi%2F10.1074%2Fjbc.M005581200&rft_id=info%3Apmid%2F10945991&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li> <li><cite class="citation journal">Hartley JL, Temple GF, Brasch MA (2001). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC310948">„DNA cloning using in vitro site-specific recombination”</a>. <i>Genome Res</i>. <b>10</b> (11): 1788—95. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <span class="plainlinks"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC310948">310948</a> <span typeof="mw:File"><span title="Слободан приступ"><img alt="Слободан приступ" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png" decoding="async" width="9" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/14px-Lock-green.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/18px-Lock-green.svg.png 2x" data-file-width="512" data-file-height="813" /></span></span></span>. <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/11076863">11076863</a>. <a href="/wiki/Digitalni_identifikator_objekta" title="Digitalni identifikator objekta">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1101%2Fgr.143000">10.1101/gr.143000</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3AMetabotropni+glutamatni+receptor+1&rft.atitle=DNA+cloning+using+in+vitro+site-specific+recombination&rft.au=Brasch%2C+MA&rft.au=Temple%2C+GF&rft.aufirst=JL&rft.aulast=Hartley&rft.date=2001&rft.genre=article&rft.issue=11&rft.jtitle=Genome+Res.&rft.pages=1788-95&rft.volume=10&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC310948&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC310948&rft_id=info%3Adoi%2F10.1101%2Fgr.143000&rft_id=info%3Apmid%2F11076863&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="Vidi_još"><span id="Vidi_jo.C5.A1"></span>Vidi još</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&veaction=edit&section=6" title="Уредите одељак „Vidi još”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&action=edit&section=6" title="Уреди извор одељка: Vidi još"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Metabotropni_glutamatni_receptor" title="Metabotropni glutamatni receptor">Metabotropni glutamatni receptor</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Spoljašnje_veze"><span id="Spolja.C5.A1nje_veze"></span>Spoljašnje veze</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&veaction=edit&section=7" title="Уредите одељак „Spoljašnje veze”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Metabotropni_glutamatni_receptor_1&action=edit&section=7" title="Уреди извор одељка: Spoljašnje veze"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><cite class="citation web"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20160303204041/http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2268">„Metabotropic Glutamate Receptors: mGlu<sub>1</sub>”</a>. <i>IUPHAR Database of Receptors and Ion Channels</i>. International Union of Basic and Clinical Pharmacology. Архивирано из <a rel="nofollow" class="external text" href="http://www.iuphar-db.org/GPCR/ReceptorDisplayForward?receptorID=2268">оригинала</a> 03. 03. 2016. г.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fsr.wikipedia.org%3AMetabotropni+glutamatni+receptor+1&rft.atitle=Metabotropic+Glutamate+Receptors%3A+mGlu%3Csub%3E1%3C%2Fsub%3E&rft.genre=unknown&rft.jtitle=IUPHAR+Database+of+Receptors+and+Ion+Channels&rft_id=http%3A%2F%2Fwww.iuphar-db.org%2FGPCR%2FReceptorDisplayForward%3FreceptorID%3D2268&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></li></ul> <div style="clear:both;"></div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r25469611">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output 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data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1isr">1isr</a></span></b>: Kristalna struktura ekstracelularnog domena metabotropnog glutamatnog receptora 1 u kompleksu sa glutamatom i jonom gadolinijuma</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:PDB_1iss_EBI.jpg" class="mw-file-description" title="1iss: Kristalna struktura ekstracelularnog domena metabotropnog glutamatnog receptora 1 u kompleksu sa antagonistom"><img alt="1iss: Kristalna struktura ekstracelularnog domena metabotropnog glutamatnog receptora 1 u kompleksu sa antagonistom" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/36/PDB_1iss_EBI.jpg/180px-PDB_1iss_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/36/PDB_1iss_EBI.jpg/270px-PDB_1iss_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/36/PDB_1iss_EBI.jpg/360px-PDB_1iss_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1iss">1iss</a></span></b>: Kristalna struktura ekstracelularnog domena metabotropnog glutamatnog receptora 1 u kompleksu sa antagonistom</div> </li> </ul></div></div></div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r25469611"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r24365370"></div><div role="navigation" class="navbox" aria-labelledby="Transmembranski_receptor:_receptori_spregnuti_s_G_proteinom" style="padding:3px"><table class="nowraplinks 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class="navbox-group" style="width:1%;text-align:left; background-color: AntiqueWhite"><a href="/wiki/Rodopsinu-sli%C4%8Dni_receptori" title="Rodopsinu-slični receptori">Klasa A</a>: <a href="/wiki/Rodopsin" title="Rodopsin">Rodopsinu</a> slični</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:8em;"><a href="/wiki/%D0%9D%D0%B5%D1%83%D1%80%D0%BE%D1%82%D1%80%D0%B0%D0%BD%D1%81%D0%BC%D0%B8%D1%82%D0%B5%D1%80" title="Неуротрансмитер">Neurotransmiter</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/Adrenergi%C4%8Dki_receptor" title="Adrenergički receptor">Adrenergički</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><a href="/wiki/Alfa-1_adrenergi%C4%8Dki_receptor" title="Alfa-1 adrenergički receptor">α1</a> (<a href="/wiki/Alfa-1A_adrenergi%C4%8Dki_receptor" title="Alfa-1A adrenergički receptor">A</a>, <a href="/wiki/Alfa-1B_adrenergi%C4%8Dki_receptor" title="Alfa-1B adrenergički receptor">B</a>, <a href="/wiki/Alfa-1D_adrenergi%C4%8Dki_receptor" title="Alfa-1D adrenergički receptor">D</a>) •  <a href="/wiki/Alfa-2_adrenergi%C4%8Dki_receptor" title="Alfa-2 adrenergički receptor">α2</a> (<a href="/wiki/Alfa-2A_adrenergi%C4%8Dki_receptor" title="Alfa-2A adrenergički receptor">A</a>, <a href="/wiki/Alfa-2B_adrenergi%C4%8Dki_receptor" title="Alfa-2B adrenergički receptor">B</a>, <a href="/wiki/Alfa-2C_adrenergi%C4%8Dki_receptor" title="Alfa-2C adrenergički receptor">C</a>) •  <a href="/wiki/Beta-1_adrenergi%C4%8Dki_receptor" title="Beta-1 adrenergički receptor">β1</a> •  <a href="/wiki/Beta-2_adrenergi%C4%8Dki_receptor" title="Beta-2 adrenergički receptor">β2</a> •  <a href="/wiki/Beta-3_adrenergi%C4%8Dki_receptor" title="Beta-3 adrenergički receptor">β3</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/Purinski_receptor" title="Purinski receptor">Purinski</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Adenozinski_receptor" title="Adenozinski receptor">Adenozinski</a> (<a href="/wiki/Adenozinski_A1_receptor" title="Adenozinski A1 receptor">A1</a>, <a href="/wiki/Adenozinski_A2A_receptor" title="Adenozinski A2A receptor">A2A</a>, <a href="/wiki/Adenozinski_A2B_receptor" title="Adenozinski A2B receptor">A2B</a>, <a href="/wiki/Adenozinski_A3_receptor" title="Adenozinski A3 receptor">A3</a>) •  <a href="/wiki/P2Y_receptor" title="P2Y receptor">P2Y</a> (<a href="/wiki/P2RY1" title="P2RY1">1</a>, <a href="/wiki/P2RY2" title="P2RY2">2</a>, <a href="/wiki/P2RY4" title="P2RY4">4</a>, <a href="/wiki/LPAR6" title="LPAR6">5</a>, <a href="/wiki/P2RY6" title="P2RY6">6</a>, <a href="/wiki/P2RY8" title="P2RY8">8</a>, <a href="/wiki/GPR23" class="mw-redirect" title="GPR23">9</a>, <a href="/wiki/P2RY10" title="P2RY10">10</a>, <a href="/wiki/P2RY11" title="P2RY11">11</a>, <a href="/wiki/P2Y12" title="P2Y12">12</a>, <a href="/wiki/P2RY13" title="P2RY13">13</a>, <a href="/wiki/P2RY14" title="P2RY14">14</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/5-HT_receptor" title="5-HT receptor">Serotoninski</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><i>(svi osim 5-HT3)</i> <a href="/wiki/5-HT1_receptor" title="5-HT1 receptor">5-HT1</a> (<a href="/wiki/5-HT1A_receptor" title="5-HT1A receptor">A</a>, <a href="/wiki/5-HT1B_receptor" title="5-HT1B receptor">B</a>, <a href="/wiki/5-HT1D_receptor" title="5-HT1D receptor">D</a>, <a href="/wiki/5-HT1E_receptor" title="5-HT1E receptor">E</a>, <a href="/wiki/5-HT1F_receptor" title="5-HT1F receptor">F</a>) •  <a href="/wiki/5-HT2_receptor" title="5-HT2 receptor">5-HT2</a> (<a href="/wiki/5-HT2A_receptor" title="5-HT2A receptor">A</a>, <a href="/wiki/5-HT2B_receptor" title="5-HT2B receptor">B</a>, <a href="/wiki/5-HT2C_receptor" title="5-HT2C receptor">C</a>) •  <i>5-HT</i> (<a href="/wiki/5-HT4_receptor" title="5-HT4 receptor">4</a>, <a href="/wiki/5-HT5A_receptor" title="5-HT5A receptor">5A</a>, <a href="/wiki/5-HT6_receptor" title="5-HT6 receptor">6</a>, <a href="/wiki/5-HT7_receptor" title="5-HT7 receptor">7</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;">Drugi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Muskarinski_acetilholinski_receptor" title="Muskarinski acetilholinski receptor">Acetilholin</a> (<a href="/wiki/Muskarinski_acetilholinski_receptor_M1" title="Muskarinski acetilholinski receptor M1">M1</a>, <a href="/wiki/Muskarinski_acetilholinski_receptor_M2" title="Muskarinski acetilholinski receptor M2">M2</a>, <a href="/wiki/Muskarinski_acetilholinski_receptor_M3" title="Muskarinski acetilholinski receptor M3">M3</a>, <a href="/wiki/Muskarinski_acetilholinski_receptor_M4" title="Muskarinski acetilholinski receptor M4">M4</a>, <a href="/wiki/Muskarinski_acetilholinski_receptor_M5" title="Muskarinski acetilholinski receptor M5">M5</a>) •  <a href="/wiki/Dopaminski_receptor" title="Dopaminski receptor">Dopamin</a> (<a href="/wiki/Dopaminski_receptor_D1" title="Dopaminski receptor D1">D1</a>, <a href="/wiki/Dopaminski_receptor_D2" title="Dopaminski receptor D2">D2</a>, <a href="/wiki/Dopaminski_receptor_D3" title="Dopaminski receptor D3">D3</a>, <a href="/wiki/Dopaminski_receptor_D4" title="Dopaminski receptor D4">D4</a>, <a href="/wiki/Dopaminski_receptor_D5" title="Dopaminski receptor D5">D5</a>) •  <a href="/wiki/Histaminski_receptor" title="Histaminski receptor">Histamin</a> (<a href="/wiki/Histaminski_H1_receptor" title="Histaminski H1 receptor">H1</a>, <a href="/wiki/Histaminski_H2_receptor" title="Histaminski H2 receptor">H2</a>, <a href="/wiki/Histaminski_H3_receptor" title="Histaminski H3 receptor">H3</a>, <a href="/wiki/Histaminski_H4_receptor" title="Histaminski H4 receptor">H4</a>) •  <a href="/wiki/Melatoninski_receptor" title="Melatoninski receptor">Melatonin</a> (<a href="/wiki/Melatoninski_receptor_1A" title="Melatoninski receptor 1A">1A</a>, <a href="/wiki/Melatoninski_receptor_1B" title="Melatoninski receptor 1B">1B</a>, <a href="/wiki/Melatoninski_receptor_1C" title="Melatoninski receptor 1C">1C</a>) •  <a href="/wiki/Trag_amin-asocirani_receptor" title="Trag amin-asocirani receptor">TAAR</a> (<a href="/wiki/TAAR1" title="TAAR1">1</a>, <a href="/wiki/TAAR2" title="TAAR2">2</a>, <a href="/wiki/TAAR3" title="TAAR3">3</a>, <a href="/wiki/TAAR5" title="TAAR5">5</a>, <a href="/wiki/TAAR6" title="TAAR6">6</a>, <a href="/wiki/TAAR8" title="TAAR8">8</a>, <a href="/wiki/TAAR9" title="TAAR9">9</a>)</div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:8em;">Metaboliti i<br />signalni molekuli</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/Eikozanoidni_receptor" title="Eikozanoidni receptor">Eikozanoidni</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><i>CysLT</i> (<a href="/wiki/Cisteinil_leukotrienski_receptor_1" title="Cisteinil leukotrienski receptor 1">1</a>, <a href="/wiki/Cisteinil_leukotrienski_receptor_2" title="Cisteinil leukotrienski receptor 2">2</a>) •  <a href="/wiki/Leukotrien_B4" title="Leukotrien B4">LTB4</a> (<a href="/wiki/Leukotrienski_B4_receptor" title="Leukotrienski B4 receptor">1</a>, <a href="/wiki/Leukotrienski_B4_receptor_2" title="Leukotrienski B4 receptor 2">2</a>) •  <a href="/wiki/Formil_peptidni_receptor_2" title="Formil peptidni receptor 2"> FPRL1</a> •  <a href="/wiki/Oksoeikozanoidni_receptor_1" title="Oksoeikozanoidni receptor 1">OXE</a> •  <a href="/wiki/Prostaglandinski_receptor" title="Prostaglandinski receptor">Prostaglandin</a> (<i>DP</i> (<a href="/wiki/Prostaglandinski_D2_receptor" title="Prostaglandinski D2 receptor">1</a>, <a href="/wiki/GPR44" title="GPR44">2</a>), <i>EP</i> (<a href="/wiki/EP1_receptor" title="EP1 receptor">1</a>, <a href="/wiki/Prostaglandinski_E2_receptor" title="Prostaglandinski E2 receptor">2</a>, <a href="/wiki/Prostaglandinski_E_receptor_3" title="Prostaglandinski E receptor 3">3</a>, <a href="/wiki/EP4_receptor" title="EP4 receptor">4</a>), <a href="/wiki/Prostaglandinski_F_receptor" title="Prostaglandinski F receptor">FP</a>) •  <a href="/wiki/Prostaciklinski_receptor" title="Prostaciklinski receptor">Prostaciklin</a> •  <a href="/wiki/Tromboksanski_receptor" title="Tromboksanski receptor"> Tromboksan</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;">Drugi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Receptor_%C5%BEu%C4%8Dne_kiseline" title="Receptor žučne kiseline">Žučna kiselina</a> •  <a href="/wiki/Kanabinoidni_receptor" title="Kanabinoidni receptor">Kanabinoidni</a> (<a href="/wiki/Kanabinoidni_receptor_tip_1" title="Kanabinoidni receptor tip 1">CB1</a>, <a href="/wiki/Kanabinoidni_receptor_2" title="Kanabinoidni receptor 2">CB2</a>, <i>GPR</i> (<a href="/wiki/GPR18" title="GPR18">18</a>, <a href="/wiki/GPR55" title="GPR55">55</a>, <a href="/wiki/GPR119" title="GPR119">119</a>)) •  <a href="/wiki/GPR183" title="GPR183">EBI2</a> •  <a href="/wiki/GPR30" title="GPR30">Estrogen</a> •  <a href="/wiki/Receptor_slobodnih_masnih_kiselina" title="Receptor slobodnih masnih kiselina">Slobodna masna kiselina</a> (<a href="/wiki/Receptor_slobodnih_masnih_kiselina_1" title="Receptor slobodnih masnih kiselina 1">1</a>, <a href="/wiki/Receptor_slobodnih_masnih_kiselina_2" title="Receptor slobodnih masnih kiselina 2">2</a>, <a href="/wiki/Receptor_slobodnih_masnih_kiselina_3" title="Receptor slobodnih masnih kiselina 3">3</a>, <a href="/wiki/GPR42" title="GPR42">4</a>) •  <a href="/wiki/GPR81" title="GPR81">Laktat</a> • <a href="/wiki/Lizofosfatidna_kiselina" title="Lizofosfatidna kiselina">Lizofosfatidna kiselina</a> (<a href="/wiki/LPAR1" title="LPAR1">1</a>, <a href="/wiki/LPAR2" title="LPAR2">2</a>, <a href="/wiki/LPAR3" title="LPAR3">3</a>, <a href="/wiki/LPAR4" title="LPAR4">4</a>, <a href="/wiki/LPAR5" title="LPAR5">5</a>, <a href="/wiki/LPAR6" title="LPAR6">6</a>) • <a href="/wiki/Lizofosfolipidni_receptor" title="Lizofosfolipidni receptor">Lizofosfolipid</a> (<a href="/wiki/S1PR1" title="S1PR1">1</a>, <a href="/wiki/LPAR1" title="LPAR1">2</a>, <a href="/wiki/S1PR3" title="S1PR3">3</a>, <a href="/wiki/LPAR2" title="LPAR2">4</a>, <a href="/wiki/S1PR2" title="S1PR2">5</a>, <a href="/wiki/S1PR4" title="S1PR4">6</a>, <a href="/wiki/LPAR3" title="LPAR3">7</a>, <a href="/wiki/S1PR5" title="S1PR5">8</a>) •  <i><a href="/wiki/%D0%9D%D0%B8%D0%B0%D1%86%D0%B8%D0%BD" title="Ниацин">Niacin</a></i> (<a href="/wiki/Niacinski_receptor_1" title="Niacinski receptor 1">1</a>, <a href="/wiki/Niacinski_receptor_2" title="Niacinski receptor 2">2</a>) •  <a href="/wiki/OXGR1" title="OXGR1">Oksoglutarat</a> •  <a href="/wiki/Receptor_trombocit_aktiviraju%C4%87eg_faktora" title="Receptor trombocit aktivirajućeg faktora">PAF</a> •  <a href="/wiki/Sfingozin-1-fosfat" title="Sfingozin-1-fosfat">Sfingozin-1-fosfat</a> (<a href="/wiki/S1PR1" title="S1PR1">1</a>, <a href="/wiki/S1PR2" title="S1PR2">2</a>, <a href="/wiki/S1PR3" title="S1PR3">3</a>, <a href="/wiki/S1PR4" title="S1PR4">4</a>, <a href="/wiki/S1PR5" title="S1PR5">5</a>) •  <a href="/wiki/SUCNR1" title="SUCNR1">Sukcinat</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:8em;">Peptid</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/GPCR_neuropeptidni_receptor" title="GPCR neuropeptidni receptor">Neuropeptidni</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><a href="/wiki/Neuropeptidni_B/W_receptor" title="Neuropeptidni B/W receptor">B/W</a> (<a href="/wiki/Neuropeptidni_B/W_receptor_1" title="Neuropeptidni B/W receptor 1">1</a>, <a href="/wiki/Neuropeptidni_B/W_receptor_2" title="Neuropeptidni B/W receptor 2">2</a>) •  <a href="/wiki/Neuropeptidni_FF_receptor" title="Neuropeptidni FF receptor">FF</a> (<a href="/wiki/Neuropeptidni_FF_receptor_1" title="Neuropeptidni FF receptor 1">1</a>, <a href="/wiki/Neuropeptidni_FF_receptor_2" title="Neuropeptidni FF receptor 2">2</a>) •  <a href="/wiki/Neuropeptidni_S_receptor" title="Neuropeptidni S receptor">S</a> •  <a href="/wiki/Neuropeptidni_Y_receptor" title="Neuropeptidni Y receptor">Y</a> (<a href="/wiki/Neuropeptidni_Y_receptor_Y1" title="Neuropeptidni Y receptor Y1">1</a>, <a href="/wiki/Neuropeptidni_Y_receptor_Y2" title="Neuropeptidni Y receptor Y2">2</a>, <a href="/wiki/Pankreasni_polipeptidni_receptor_1" title="Pankreasni polipeptidni receptor 1">4</a>, <a href="/wiki/Neuropeptidni_Y_receptor_Y5" title="Neuropeptidni Y receptor Y5">5</a>) •  <i>Neuromedin</i> (<a href="/wiki/Neuromedinski_B_receptor" title="Neuromedinski B receptor">B</a>, <a href="/wiki/Neuromedinski_U_receptor" title="Neuromedinski U receptor">U</a> (<a href="/wiki/Neuromedinski_U_receptor_1" title="Neuromedinski U receptor 1">1</a>, <a href="/wiki/Neuromedinski_U_receptor_2" title="Neuromedinski U receptor 2">2</a>)) •  <a href="/wiki/Neurotenzinski_receptor" title="Neurotenzinski receptor">Neurotenzin</a> (<a href="/wiki/Neurotenzinski_receptor_1" title="Neurotenzinski receptor 1">1</a>, <a href="/wiki/Neurotenzinski_receptor_2" title="Neurotenzinski receptor 2">2</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;">Drugi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Anafilatoksinski_receptori" title="Anafilatoksinski receptori"> Anafilatoksin</a> (<a href="/wiki/C3a_receptor" title="C3a receptor">C3a</a>, <a href="/wiki/C5a_receptor" title="C5a receptor">C5a</a>) •  <a href="/wiki/Angiotenzinski_receptor" title="Angiotenzinski receptor">Angiotenzin</a> (<a href="/wiki/AGTR1" title="AGTR1">1</a>, <a href="/wiki/AGTR2" title="AGTR2">2</a>) •  <a href="/wiki/Apelinski_receptor" title="Apelinski receptor">Apelin</a> •  <a href="/wiki/Bombezinski_receptor" title="Bombezinski receptor">Bombezin</a> (<a href="/wiki/Bombezinu-sli%C4%8Dan_receptor_3" title="Bombezinu-sličan receptor 3">BRS3</a>, <a href="/wiki/Gastrin-osloba%C4%91aju%C4%87i_peptidni_receptor" title="Gastrin-oslobađajući peptidni receptor">GRPR</a>, <a href="/wiki/Neuromedinski_B_receptor" title="Neuromedinski B receptor">NMBR</a>) •  <a href="/wiki/Bradikininski_receptor" title="Bradikininski receptor">Bradikinin</a> (<a href="/wiki/Bradikininski_receptor_B1" title="Bradikininski receptor B1">B1</a>, <a href="/wiki/Bradikininski_receptor_B2" title="Bradikininski receptor B2">B2</a>) •  <a href="/wiki/Hemokinski_receptor" title="Hemokinski receptor">Hemokin</a> •  <a href="/wiki/Holecistokininski_receptor" title="Holecistokininski receptor">Holecistokinin</a> (<a href="/wiki/Holecistokininski_receptor_A" title="Holecistokininski receptor A">A</a>, <a href="/wiki/Holecistokininski_receptor_B" title="Holecistokininski receptor B">B</a>) •  <a href="/wiki/Endotelinski_receptor" title="Endotelinski receptor">Endotelin</a> (<a href="/wiki/Endotelinski_receptor_tip_A" title="Endotelinski receptor tip A">A</a>, <a href="/wiki/Endotelinski_receptor_tip_B" title="Endotelinski receptor tip B">B</a>) •  <a href="/wiki/Formil_peptidni_receptor" title="Formil peptidni receptor">Formil peptid</a> (<a href="/wiki/Formil_peptidni_receptor_1" title="Formil peptidni receptor 1">1</a>, <a href="/wiki/Formil_peptidni_receptor_2" title="Formil peptidni receptor 2">2</a>, <a href="/wiki/Formil_peptidni_receptor_3" title="Formil peptidni receptor 3">3</a>) •  <a href="/wiki/FSH-receptor" title="FSH-receptor">FSH</a> •  <a href="/wiki/Galaninski_receptor" title="Galaninski receptor">Galanin</a> (<a href="/wiki/Galaninski_receptor_1" title="Galaninski receptor 1">1</a>, <a href="/wiki/Galaninski_receptor_2" title="Galaninski receptor 2">2</a>, <a href="/wiki/Galaninski_receptor_3" title="Galaninski receptor 3">3</a>) •  <a href="/wiki/GHB_receptor" title="GHB receptor">GHB receptor</a> •  <a href="/wiki/Gonadotropin-osloba%C4%91aju%C4%87i_hormon_receptor" title="Gonadotropin-oslobađajući hormon receptor">Gonadotropin-oslobađajući hormon</a> (<a href="/wiki/GNRHR" title="GNRHR">1</a>, <a href="/wiki/GNRHR2" title="GNRHR2">2</a>) •  <a href="/wiki/Hormon_rasta_osloba%C4%91aju%C4%87i_receptor" class="mw-redirect" title="Hormon rasta oslobađajući receptor">Grelin</a> •  <a href="/wiki/KISS1R" title="KISS1R"> Kispeptin</a> •  <a href="/wiki/LHCGR" title="LHCGR">Luteinizirajući hormon/horiogonadotropin</a> •  <a href="/wiki/MAS1_onkogen" title="MAS1 onkogen">MAS</a> (<a href="/wiki/MAS1" title="MAS1">1</a>, <a href="/wiki/MAS1L" title="MAS1L">1L</a>, <a href="/wiki/MRGPRD" title="MRGPRD">D</a>, <a href="/wiki/MRGPRE" title="MRGPRE">E</a>, <a href="/wiki/MRGPRF" title="MRGPRF">F</a>, <a href="/wiki/MRGPRG" title="MRGPRG">G</a>, <a href="/wiki/MRGPRX1" title="MRGPRX1">X1</a>, <a href="/wiki/MRGPRX2" title="MRGPRX2">X2</a>, <a href="/wiki/MRGPRX3" title="MRGPRX3">X3</a>, <a href="/wiki/MRGPRX4" title="MRGPRX4">X4</a>) •  <a href="/wiki/Melanokortinski_receptor" title="Melanokortinski receptor">Melanokortin</a> (<a href="/wiki/Melanokortinski_1_receptor" title="Melanokortinski 1 receptor">1</a>, <a href="/wiki/ACTH_receptor" title="ACTH receptor">2</a>, <a href="/wiki/Melanokortinski_3_receptor" title="Melanokortinski 3 receptor">3</a>, <a href="/wiki/Melanokortinski_4_receptor" title="Melanokortinski 4 receptor">4</a>, <a href="/wiki/Melanokortinski_5_receptor" title="Melanokortinski 5 receptor">5</a>) •  <a href="/wiki/Melanin-koncentriraju%C4%87i_hormonski_receptor" title="Melanin-koncentrirajući hormonski receptor">MCHR</a> (<a href="/wiki/Melanin-koncentriraju%C4%87i_hormonski_receptor_1" title="Melanin-koncentrirajući hormonski receptor 1">1</a>, <a href="/wiki/Melanin-koncentriraju%C4%87i_hormonski_receptor_2" title="Melanin-koncentrirajući hormonski receptor 2">2</a>) •  <a href="/wiki/Motilin_receptor" title="Motilin receptor">Motilin</a> •  <a href="/wiki/Opioidni_receptor" title="Opioidni receptor">Opioidni</a> (<a href="/wiki/Delta_opioidni_receptor" title="Delta opioidni receptor">δ</a>, <a href="/wiki/Kapa_opioidni_receptor" title="Kapa opioidni receptor">κ</a>, <a href="/wiki/Mi_opioidni_receptor" title="Mi opioidni receptor">μ</a>, <a href="/wiki/Nociceptinski_receptor" title="Nociceptinski receptor">Nociceptin</a> & <a href="/wiki/OGFr" title="OGFr">ζ</a>, ali ne <a href="/wiki/Sigma_receptor" title="Sigma receptor">σ</a>) •  <a href="/wiki/Oreksinski_receptor" title="Oreksinski receptor">Oreksin</a> (<a href="/wiki/Oreksinski_receptor_1" title="Oreksinski receptor 1">1</a>, <a href="/wiki/Oreksinski_receptor_2" title="Oreksinski receptor 2">2</a>) •  <a href="/wiki/Oksitocinski_receptor" title="Oksitocinski receptor">Oksitocin</a> •  <a href="/wiki/Prokineticinski_receptor" title="Prokineticinski receptor">Prokineticin</a> (<a href="/wiki/Prokineticinski_receptor_1" title="Prokineticinski receptor 1">1</a>, <a href="/wiki/Prokineticinski_receptor_2" title="Prokineticinski receptor 2">2</a>) •  <a href="/wiki/PRRP" title="PRRP">Prolaktin-oslobađajući peptid</a> •  <a href="/wiki/Relaksinski_receptor" title="Relaksinski receptor">Relaksin</a> (<a href="/wiki/RXFP1" title="RXFP1">1</a>, <a href="/wiki/RXFP2" title="RXFP2">2</a>, <a href="/wiki/RXFP3" title="RXFP3">3</a>, <a href="/wiki/RXFP4" title="RXFP4">4</a>) •  <a href="/wiki/Somatostatinski_receptor" title="Somatostatinski receptor">Somatostatin</a> (<a href="/wiki/Somatostatinski_receptor_1" title="Somatostatinski receptor 1">1</a>, <a href="/wiki/Somatostatinski_receptor_2" title="Somatostatinski receptor 2">2</a>, <a href="/wiki/Somatostatinski_receptor_3" title="Somatostatinski receptor 3">3</a>, <a href="/wiki/Somatostatinski_receptor_4" title="Somatostatinski receptor 4">4</a>, <a href="/wiki/Somatostatinski_receptor_5" title="Somatostatinski receptor 5">5</a>) •  <a href="/wiki/Tahikininski_receptor" title="Tahikininski receptor">Tahikinin</a> (<a href="/wiki/Tahikininski_receptor_1" title="Tahikininski receptor 1">1</a>, <a href="/wiki/Tahikininski_receptor_2" title="Tahikininski receptor 2">2</a>, <a href="/wiki/Tahikininski_receptor_3" title="Tahikininski receptor 3">3</a>) •  <a href="/wiki/Tirotropinski_receptor" title="Tirotropinski receptor">Tirotropin</a> •  <a href="/wiki/TRHR" title="TRHR">Tirotropin-oslobađajući hormon</a> •  <a href="/wiki/Urotenzin-II_receptor" title="Urotenzin-II receptor">Urotenzin-II</a> •  <a href="/wiki/Vazopresinski_receptor" title="Vazopresinski receptor">Vazopresin</a> (<a href="/wiki/Arginin_vazopresinski_receptor_1A" title="Arginin vazopresinski receptor 1A">1A</a>, <a href="/wiki/Arginin_vazopresinski_receptor_1B" title="Arginin vazopresinski receptor 1B">1B</a>, <a href="/wiki/Arginin_vazopresinski_receptor_2" title="Arginin vazopresinski receptor 2">2</a>)</div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:8em;">Razno</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><a href="/wiki/Orfan_receptor" title="Orfan receptor">Orfan</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><i>GPR</i> (<a href="/wiki/GPR1" title="GPR1">1</a>, <a href="/wiki/GPR3" title="GPR3">3</a>, <a href="/wiki/GPR4" title="GPR4">4</a>, <a href="/wiki/GPR6" title="GPR6">6</a>, <a href="/wiki/GPR12" title="GPR12">12</a>, <a href="/wiki/GPR15" title="GPR15">15</a>, <a href="/wiki/GPR17" title="GPR17">17</a>, <a href="/wiki/GPR18" title="GPR18">18</a>, <a href="/wiki/GPR19" title="GPR19">19</a>, <a href="/wiki/GPR20" title="GPR20">20</a>, <a href="/wiki/GPR21" title="GPR21">21</a>, <a href="/wiki/GPR22" title="GPR22">22</a>, <a href="/wiki/LPAR4" title="LPAR4">23</a>, <a href="/wiki/GPR25" title="GPR25">25</a>, <a href="/wiki/GPR26" title="GPR26">26</a>, <a href="/wiki/GPR27" title="GPR27">27</a>, <a href="/wiki/GPR31" title="GPR31">31</a>, <a href="/wiki/GPR32" title="GPR32">32</a>, <a href="/wiki/GPR33" title="GPR33">33</a>, <a href="/wiki/GPR34" title="GPR34">34</a>, <a href="/wiki/GPR35" title="GPR35">35</a>, <a href="/wiki/GPR37" title="GPR37">37</a>, <a href="/wiki/GPR39" title="GPR39">39</a>, <a href="/wiki/GPR42" title="GPR42">42</a>, <a href="/wiki/GPR44" title="GPR44">44</a>, <a href="/wiki/GPR45" title="GPR45">45</a>, <a href="/wiki/GPR50" title="GPR50">50</a>, <a href="/wiki/GPR52" title="GPR52">52</a>, <a href="/wiki/GPR55" title="GPR55">55</a>, <a href="/wiki/GPR61" title="GPR61">61</a>, <a href="/wiki/GPR62" title="GPR62">62</a>, <a href="/wiki/GPR63" title="GPR63">63</a>, <a href="/wiki/GPR65" title="GPR65">65</a>, <a href="/wiki/GPR68" title="GPR68">68</a>, <a href="/wiki/GPR75" title="GPR75">75</a>, <a href="/wiki/GPR77" title="GPR77">77</a>, <a href="/wiki/GPR78" title="GPR78">78</a>, <a href="/wiki/GPR81" title="GPR81">81</a>, <a href="/wiki/GPR82" title="GPR82">82</a>, <a href="/wiki/GPR83" title="GPR83">83</a>, <a href="/wiki/GPR84" title="GPR84">84</a>, <a href="/wiki/GPR85" title="GPR85">85</a>, <a href="/wiki/GPR87" title="GPR87">87</a>, <a href="/wiki/GPR88" title="GPR88">88</a>, <a href="/wiki/LPAR5" title="LPAR5">92</a>, <a href="/wiki/GPR101" title="GPR101">101</a>, <a href="/wiki/GPR103" title="GPR103">103</a>, <a href="/wiki/Niacinski_receptor_1" title="Niacinski receptor 1">109A</a>, <a href="/wiki/Niacinski_receptor_2" title="Niacinski receptor 2">109B</a>, <a href="/wiki/GPR119" title="GPR119">119</a>, <a href="/wiki/GPR120" title="GPR120">120</a>, <a href="/wiki/GPR132" title="GPR132">132</a>, <a href="/wiki/GPR135" title="GPR135">135</a>, <a href="/wiki/GPR137B" title="GPR137B">137B</a>, <a href="/wiki/GPR139" title="GPR139">139</a>, <a href="/wiki/GPR141" title="GPR141">141</a>, <a href="/wiki/GPR142" title="GPR142">142</a>, <a href="/wiki/GPR146" title="GPR146">146</a>, <a href="/wiki/GPR148" title="GPR148">148</a>, <a href="/wiki/GPR149" title="GPR149">149</a>, <a href="/wiki/GPR150" title="GPR150">150</a>, <a href="/wiki/GPR151" title="GPR151">151</a>, <a href="/wiki/GPR152" title="GPR152">152</a>, <a href="/wiki/GPR153" title="GPR153">153</a>, <a href="/wiki/GPR160" title="GPR160">160</a>, <a href="/wiki/GPR161" title="GPR161">161</a>, <a href="/wiki/GPR162" title="GPR162">162</a>, <a href="/wiki/GPR171" title="GPR171">171</a>, <a href="/wiki/GPR173" title="GPR173">173</a>, <a href="/wiki/GPR174" title="GPR174">174</a>, <a href="/wiki/GPR176" title="GPR176">176</a>, <a href="/wiki/GPR177" title="GPR177">177</a>, <a href="/wiki/GPR182" title="GPR182">182</a>, <a href="/wiki/GPR183" title="GPR183">183</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;width:8em;"><i>Drugi</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/GPR182" title="GPR182">Adrenomedulin</a> •  <a href="/wiki/Mirisni_receptori" title="Mirisni receptori">Mirisni</a> •  <a href="/wiki/Opsin" title="Opsin">Opsin</a> (<a href="/wiki/OPN3" title="OPN3">3</a>, <a href="/wiki/Melanopsin" title="Melanopsin">4</a>, <a href="/wiki/OPN5" title="OPN5">5</a>, <a href="/wiki/OPN1LW" title="OPN1LW">1LW</a>, <a href="/wiki/OPN1MW" title="OPN1MW">1MW</a>, <a href="/wiki/OPN1SW" title="OPN1SW">1SW</a>, <a href="/wiki/Retinalni_G_protein_spregnuti_receptor" title="Retinalni G protein spregnuti receptor">RGR</a>, <a href="/wiki/RRH" title="RRH">RRH</a>) •  <a href="/wiki/Proteazom-aktivirani_receptor" title="Proteazom-aktivirani receptor">Proteazom-aktivirani</a> (<a href="/wiki/Receptor_koagulacionog_faktora_II" title="Receptor koagulacionog faktora II">1</a>, <a href="/wiki/F2RL1" title="F2RL1">2</a>, <a href="/wiki/F2RL2" title="F2RL2">3</a>, <a href="/wiki/F2RL3" title="F2RL3">4</a>) •  <a href="/wiki/SREB" title="SREB">SREB</a> (<a href="/wiki/GPR27" title="GPR27">1</a>, <a href="/wiki/GPR85" title="GPR85">2</a>, <a href="/wiki/GPR173" title="GPR173">3</a>)</div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:left; background-color: AntiqueWhite"><a href="/wiki/Sekretinska_receptorska_familija" title="Sekretinska receptorska familija">Klasa B</a>: <a href="/wiki/Sekretinski_receptor" title="Sekretinski receptor">Sekretinu</a> slični</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;"><a href="/wiki/Orfan_receptor" title="Orfan receptor">Orfan</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><i>GPR</i> (<a href="/wiki/GPR56" title="GPR56">56</a>, <a href="/wiki/GPR64" title="GPR64">64</a>, <a href="/wiki/GPR97" title="GPR97">97</a>, <a href="/wiki/GPR98" title="GPR98">98</a>, <a href="/wiki/GPR110" title="GPR110">110</a>, <a href="/wiki/GPR111" title="GPR111">111</a>, <a href="/wiki/GPR112" title="GPR112">112</a>, <a href="/wiki/GPR113" title="GPR113">113</a>, <a href="/wiki/GPR114" title="GPR114">114</a>, <a href="/wiki/GPR115" title="GPR115">115</a>, <a href="/wiki/GPR116" title="GPR116">116</a>, <a href="/wiki/GPR123" title="GPR123">123</a>, <a href="/wiki/GPR124" title="GPR124">124</a>, <a href="/wiki/GPR125" title="GPR125">125</a>, <a href="/wiki/GPR126" title="GPR126">126</a>, <a href="/wiki/GPR128" title="GPR128">128</a>, <a href="/wiki/GPR133" title="GPR133">133</a>, <a href="/wiki/GPR143" title="GPR143">143</a>, <a href="/wiki/GPR144" title="GPR144">144</a>, <a href="/wiki/GPR155" title="GPR155">155</a>, <a href="/wiki/GPR157" title="GPR157">157</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;"><i>Drugi</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Mo%C5%BEdano_specifi%C4%8Dni_angiogenezni_inhibitor" title="Moždano specifični angiogenezni inhibitor">Moždano specifični angiogenezni inhibitor</a> (<a href="/wiki/Mo%C5%BEdano_specifi%C4%8Dni_angiogenezni_inhibitor_1" title="Moždano specifični angiogenezni inhibitor 1">1</a>, <a href="/wiki/Mo%C5%BEdano_specifi%C4%8Dni_angiogenezni_inhibitor_2" title="Moždano specifični angiogenezni inhibitor 2">2</a>, <a href="/wiki/Mo%C5%BEdano_specifi%C4%8Dni_angiogenezni_inhibitor_3" title="Moždano specifični angiogenezni inhibitor 3">3</a>) •  <a href="/wiki/Flamingo_(protein)" title="Flamingo (protein)">Kadherin</a> (<a href="/wiki/CELSR1" title="CELSR1">1</a>, <a href="/wiki/CELSR2" title="CELSR2">2</a>, <a href="/wiki/CELSR3" title="CELSR3">3</a>) •  <a href="/wiki/Kalcitoninski_receptor" title="Kalcitoninski receptor">Kalcitonin</a> •  <a href="/wiki/CALCRL" title="CALCRL">CALCRL</a> •  <a href="/wiki/CD97" title="CD97">CD97</a> •  <a href="/wiki/Kortikotropin-osloba%C4%91aju%C4%87i_hormonski_receptor" title="Kortikotropin-oslobađajući hormonski receptor">Kortikotropin-oslobađajući hormon</a> (<a href="/wiki/Kortikotropin-osloba%C4%91aju%C4%87i_hormonski_receptor_1" title="Kortikotropin-oslobađajući hormonski receptor 1">1</a>, <a href="/wiki/Kortikotropin-osloba%C4%91aju%C4%87i_hormonski_receptor_2" title="Kortikotropin-oslobađajući hormonski receptor 2">2</a>) •  <a href="/wiki/EMR_receptor" title="EMR receptor">EMR</a> (<a href="/wiki/EMR1" title="EMR1">1</a>, <a href="/wiki/EMR2" title="EMR2">2</a>, <a href="/wiki/EMR3" title="EMR3">3</a>) •  <a href="/wiki/Glukagonska_receptorska_familija" title="Glukagonska receptorska familija">Glukagon</a> (<a href="/wiki/Glukagonski_receptor" title="Glukagonski receptor">GR</a>, <a href="/wiki/Receptor_gastri%C4%8Dnog_inhibitornog_polipeptida" title="Receptor gastričnog inhibitornog polipeptida">GIPR</a>, <a href="/wiki/Receptor_glukagonu_sli%C4%8Dnog_peptida_1" title="Receptor glukagonu sličnog peptida 1">GLP1R</a>, <a href="/wiki/Receptor_glukagonu_sli%C4%8Dnog_peptida_2" title="Receptor glukagonu sličnog peptida 2">GLP2R</a>) •  <a href="/wiki/Hormon_rasta_osloba%C4%91aju%C4%87i_hormonski_receptor" title="Hormon rasta oslobađajući hormonski receptor">Hormon rasta</a> •  <a href="/wiki/ADCYAP1R1" title="ADCYAP1R1">PACAPR1</a> •  <a href="/wiki/Orfan_receptor" title="Orfan receptor">GPR</a> •  <a href="/wiki/Latrofilinski_receptor" title="Latrofilinski receptor">Latrofilin</a> (<a href="/wiki/LPHN1" title="LPHN1">1</a>, <a href="/wiki/LPHN2" title="LPHN2">2</a>, <a href="/wiki/LPHN3" title="LPHN3">3</a>, <a href="/wiki/ELTD1" title="ELTD1">ELTD1</a>) •  <a href="/wiki/Metuzalemski_protein" title="Metuzalemski protein">Metuzalemski protein</a> •  <a href="/wiki/Receptor_paratiroidnog_hormona" title="Receptor paratiroidnog hormona">Paratiroidni hormon</a> (<a href="/wiki/Receptor_paratiroidnog_hormona_1" title="Receptor paratiroidnog hormona 1">1</a>, <a href="/wiki/Receptor_paratiroidnog_hormona_2" title="Receptor paratiroidnog hormona 2">2</a>) •  <a href="/wiki/Sekretinski_receptor" title="Sekretinski receptor">Sekretin</a> •  <a href="/wiki/Receptor_vazoaktivnog_intestinalnog_peptida" title="Receptor vazoaktivnog intestinalnog peptida">Vazoaktivni intestinalni peptid</a> (<a href="/wiki/VIPR1" title="VIPR1">1</a>, <a href="/wiki/VIPR2" title="VIPR2">2</a>)</div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:left; background-color: AntiqueWhite"><a href="/wiki/Klasa_C_GPCR" title="Klasa C GPCR">Klasa C</a>: <a href="/wiki/Metabotropni_receptor" title="Metabotropni receptor">Metabotropni</a><br /><a href="/wiki/Metabotropni_glutamatni_receptor" title="Metabotropni glutamatni receptor">glutamat</a> / <a href="/wiki/Feromon" title="Feromon">feromon</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;"><a href="/wiki/Receptor_ukusa" title="Receptor ukusa">Ukus</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><i>TAS1R</i> (<a href="/wiki/TAS1R1" title="TAS1R1">1</a>, <a href="/wiki/TAS1R2" title="TAS1R2">2</a>, <a href="/wiki/TAS1R3" title="TAS1R3">3</a>) •  <i>TAS2R</i> (<a href="/wiki/TAS2R1" title="TAS2R1">1</a>, <a href="/wiki/TAS2R3" title="TAS2R3">3</a>, <a href="/wiki/TAS2R4" title="TAS2R4">4</a>, <a href="/wiki/TAS2R5" title="TAS2R5">5</a>, <a href="/wiki/TAS2R8" title="TAS2R8">8</a>, <a href="/wiki/TAS2R9" title="TAS2R9">9</a>, <a href="/wiki/TAS2R10" title="TAS2R10">10</a>, <a href="/wiki/TAS2R12" title="TAS2R12">12</a>, <a href="/wiki/TAS2R13" title="TAS2R13">13</a>, <a href="/wiki/TAS2R14" title="TAS2R14">14</a>, <a href="/wiki/TAS2R16" title="TAS2R16">16</a>, <a href="/wiki/TAS2R19" title="TAS2R19">19</a>, <a href="/wiki/TAS2R20" title="TAS2R20">20</a>, <a href="/wiki/TAS2R30" title="TAS2R30">30</a>, <a href="/wiki/TAS2R31" title="TAS2R31">31</a>, <a href="/wiki/TAS2R38" title="TAS2R38">38</a>, <a href="/wiki/TAS2R39" title="TAS2R39">39</a>, <a href="/wiki/TAS2R40" title="TAS2R40">40</a>, <a href="/wiki/TAS2R41" title="TAS2R41">41</a>, <a href="/wiki/TAS2R42" title="TAS2R42">42</a>, <a href="/wiki/TAS2R43" title="TAS2R43">43</a>, <a href="/wiki/TAS2R45" title="TAS2R45">45</a>, <a href="/wiki/TAS2R46" title="TAS2R46">46</a>, <a href="/wiki/TAS2R50" title="TAS2R50">50</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;"><i>Drugi</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Kalcijum-detektuju%C4%87i_receptor" title="Kalcijum-detektujući receptor">Kalcijum-detektujući receptor</a> •  <a href="/wiki/GABAB_receptor" title="GABAB receptor">GABA B</a> (<a href="/wiki/GABBR1" title="GABBR1">1</a>, <a href="/wiki/GABBR2" title="GABBR2">2</a>) •  <a href="/wiki/Glutamatni_receptor" title="Glutamatni receptor">Glutamatni receptor</a> (<a href="/wiki/Metabotropni_glutamatni_receptor" title="Metabotropni glutamatni receptor">Metabotropni glutamat</a> (<a class="mw-selflink selflink">1</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_2" title="Metabotropni glutamatni receptor 2">2</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_3" title="Metabotropni glutamatni receptor 3">3</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_4" title="Metabotropni glutamatni receptor 4">4</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_5" title="Metabotropni glutamatni receptor 5">5</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_6" title="Metabotropni glutamatni receptor 6">6</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_7" title="Metabotropni glutamatni receptor 7">7</a>, <a href="/wiki/Metabotropni_glutamatni_receptor_8" title="Metabotropni glutamatni receptor 8">8</a>)) •  <a href="/wiki/GPRC6A" title="GPRC6A">GPRC6A</a> •  <a href="/wiki/Orfan_receptor" title="Orfan receptor">GPR</a> (<a href="/wiki/GPR156" title="GPR156">156</a>, <a href="/wiki/GPR158" title="GPR158">158</a>, <a href="/wiki/GPR179" title="GPR179">179</a>) •  <a href="/wiki/RAIG" title="RAIG">RAIG</a> (<a href="/wiki/GPRC5A" title="GPRC5A">1</a>, <a href="/wiki/GPRC5B" title="GPRC5B">2</a>, <a href="/wiki/GPRC5C" title="GPRC5C">3</a>, <a href="/wiki/GPRC5D" title="GPRC5D">4</a>) •  <a href="/wiki/Vomeronazalni_receptor" title="Vomeronazalni receptor">VNR</a> (<a href="/wiki/VN1R1" title="VN1R1">1</a>, <a href="/wiki/VN1R2" title="VN1R2">2</a>, <a href="/wiki/VN1R3" title="VN1R3">3</a>, <a href="/wiki/VN1R5" title="VN1R5">5</a>)</div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:left; background-color: AntiqueWhite">Klasa F:<br /><a href="/wiki/Uvojiti_receptori" title="Uvojiti receptori">Frizzled</a> / <a href="/wiki/Zagla%C4%91eni_receptori" title="Zaglađeni receptori">Zaglađeni</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;">Uvojiti</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0;width:auto;;background-color: AntiqueWhite;"><div style="padding:0 0.25em"><a href="/wiki/Uvojiti_receptori" title="Uvojiti receptori">Frizzled</a> (<a href="/wiki/FZD1" title="FZD1">1</a>, <a href="/wiki/FZD2" title="FZD2">2</a>, <a href="/wiki/FZD3" title="FZD3">3</a>, <a href="/wiki/FZD4" title="FZD4">4</a>, <a href="/wiki/FZD5" title="FZD5">5</a>, <a href="/wiki/FZD6" title="FZD6">6</a>, <a href="/wiki/FZD7" title="FZD7">7</a>, <a href="/wiki/FZD8" title="FZD8">8</a>, <a href="/wiki/FZD9" title="FZD9">9</a>, <a href="/wiki/FZD10" title="FZD10">10</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align:center; width:19.1em;">Zaglađeni</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0;width:auto;"><div style="padding:0 0.25em"><a href="/wiki/Zagla%C4%91eni_receptori" title="Zaglađeni receptori">Zaglađeni</a></div></td></tr></tbody></table><div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r25469611"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r24365370"></div><div role="navigation" class="navbox" aria-labelledby="Glutamatergični_ligandi" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r25469611"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r24365379"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-прикажи"><a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:%D0%93%D0%BB%D1%83%D1%82%D0%B0%D0%BC%D0%B0%D1%82%D0%B5%D1%80%D0%B3%D0%B8%D1%87%D0%BD%D0%B8_%D0%BB%D0%B8%D0%B3%D0%B0%D0%BD%D0%B4%D0%B8" title="Шаблон:Глутаматергични лиганди"><abbr title="Погледајте шаблон" style=";;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">п</abbr></a></li><li class="nv-разговор"><a href="/wiki/%D0%A0%D0%B0%D0%B7%D0%B3%D0%BE%D0%B2%D0%BE%D1%80_%D0%BE_%D1%88%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD%D1%83:%D0%93%D0%BB%D1%83%D1%82%D0%B0%D0%BC%D0%B0%D1%82%D0%B5%D1%80%D0%B3%D0%B8%D1%87%D0%BD%D0%B8_%D0%BB%D0%B8%D0%B3%D0%B0%D0%BD%D0%B4%D0%B8" title="Разговор о шаблону:Глутаматергични лиганди"><abbr title="Разговарајте о шаблону" style=";;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">р</abbr></a></li><li class="nv-уреди"><a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A3%D1%80%D0%B5%D0%B4%D0%B8_%D1%81%D1%82%D1%80%D0%B0%D0%BD%D0%B8%D1%86%D1%83/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Glutamatergi%C4%8Dni_ligandi" title="Посебно:Уреди страницу/Шаблон:Glutamatergični ligandi"><abbr title="Уредите шаблон" style=";;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">у</abbr></a></li></ul></div><div id="Glutamatergični_ligandi" style="font-size:114%;margin:0 4em"><a href="/wiki/Glutaminska_kiselina" title="Glutaminska kiselina">Glutamatergični ligandi</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/Ligand-kontrolisani_jonski_kanali" class="mw-redirect" title="Ligand-kontrolisani jonski kanali">Jonotropni</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/AMPA_receptor" title="AMPA receptor">AMPA</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><b><a href="/wiki/Ampakin" title="Ampakin">Agonisti</a>:</b> <a href="/wiki/5-Fluoro-vilardin" class="mw-redirect" title="5-Fluoro-vilardin">5-Fluoro-vilardin</a> •  <a href="/wiki/AMPA" title="AMPA">AMPA</a> •  <a href="/wiki/Domoi%C4%8Dna_kiselina" class="mw-redirect" title="Domoična kiselina">Domoična kiselina</a> •  <a href="/wiki/Kuiskualinska_kiselina" title="Kuiskualinska kiselina">Kuiskualinska kiselina</a>; <i><a href="/wiki/Pozitivni_alosterni_modulator" title="Pozitivni alosterni modulator">Pozitivni alosterni modulatori</a>:</i> <a href="/wiki/Aniracetam" title="Aniracetam">Aniracetam</a> •  <a href="/wiki/Ciklotiazid" title="Ciklotiazid">Ciklotiazid</a> •  <a href="/wiki/CX-516" title="CX-516">CX-516</a> •  <a href="/wiki/CX-546" title="CX-546">CX-546</a> •  <a href="/wiki/CX-614" class="mw-redirect" title="CX-614">CX-614</a> •  <a href="/wiki/CX-691" class="mw-redirect" title="CX-691">CX-691</a> •  <a href="/wiki/CX-717" class="mw-redirect" title="CX-717">CX-717</a> •  <a href="/wiki/Diazoksid" title="Diazoksid">Diazoksid</a> •  <a href="/wiki/Hidrohlorotiazid" title="Hidrohlorotiazid">HCTZ</a> •  <a href="/wiki/IDRA-21" title="IDRA-21">IDRA-21</a> •  <a href="/wiki/LY-392,098" title="LY-392,098">LY-392,098</a> •  <a href="/wiki/LY-404,187" title="LY-404,187">LY-404,187</a> •  <a href="/wiki/LY-451,395" class="mw-redirect" title="LY-451,395">LY-451,395</a> •  <a href="/wiki/LY-451,646" title="LY-451,646">LY-451,646</a> •  <a href="/wiki/LY-503,430" title="LY-503,430">LY-503,430</a> •  <a href="/wiki/Oksiracetam" title="Oksiracetam">Oksiracetam</a> •  <a href="/wiki/PEPA_(lek)" title="PEPA (lek)">PEPA</a> •  <a href="/wiki/Piracetam" title="Piracetam">Piracetam</a> •  <a href="/wiki/Pramiracetam" title="Pramiracetam">Pramiracetam</a> •  <a href="/wiki/S-18986" title="S-18986">S-18986</a> •  <a href="/wiki/Sunifiram" title="Sunifiram">Sunifiram</a> •  <a href="/wiki/Unifiram" title="Unifiram">Unifiram</a><br /><b>Antagonisti:</b> <a href="/wiki/2-amino-3-(5-tert-butil-3-(fosfonometoksi)-1,2-oksazol-4-il)propanoinska_kiselina" title="2-amino-3-(5-tert-butil-3-(fosfonometoksi)-1,2-oksazol-4-il)propanoinska kiselina">ATPO</a> •  <a href="/wiki/Karoverin" title="Karoverin">Karoverin</a> •  <a href="/wiki/CNQX" title="CNQX">CNQX</a> •  <a href="/wiki/DNQX" class="mw-redirect" title="DNQX">DNQX</a> •  <a href="/wiki/GYKI-52466" class="mw-redirect" title="GYKI-52466">GYKI-52466</a> •  <a href="/wiki/NBQX" title="NBQX">NBQX</a> •  <a href="/wiki/Perampanel" title="Perampanel">Perampanel</a> •  <a href="/wiki/Talampanel" title="Talampanel">Talampanel</a> •  <a href="/wiki/Tezampanel" title="Tezampanel">Tezampanel</a>; <i><a href="/wiki/Negativni_alosterni_modulator" title="Negativni alosterni modulator">Negativni alosterni modulatori</a>:</i> <a href="/wiki/GYKI-53,655" title="GYKI-53,655">GYKI-53,655</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/NMDA_receptor" title="NMDA receptor">NMDA</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><b>Agonisti:</b> <i>Konkurentni agonisti</i>: <a href="/wiki/Aspartat" class="mw-redirect" title="Aspartat">Aspartat</a> •  <a href="/wiki/Glutamat" class="mw-redirect" title="Glutamat">Glutamat</a> •  <a href="/wiki/Homohinolinska_kiselina" title="Homohinolinska kiselina">Homohinolinska kiselina</a> •  <a href="/wiki/Ibotenska_kiselina" title="Ibotenska kiselina">Ibotenska kiselina</a> •  <a href="/wiki/NMDA" class="mw-redirect" title="NMDA">NMDA</a> •  <a href="/wiki/Hinolinska_kiselina" title="Hinolinska kiselina">Hinolinska kiselina</a> •  <a href="/wiki/Tetrazolilglicin" title="Tetrazolilglicin">Tetrazolilglicin</a>; <i>Agonisti glicinskog mesta:</i> <a href="/wiki/ACBD_(lek)" title="ACBD (lek)">ACBD</a> •  <a href="/wiki/1-Aminociklopropan-1-karboksilna_kiselina" title="1-Aminociklopropan-1-karboksilna kiselina">ACPC</a> •  <a href="/wiki/ACPD" title="ACPD">ACPD</a> •  <a href="/wiki/%D0%90%D0%BB%D0%B0%D0%BD%D0%B8%D0%BD" title="Аланин">Alanin</a> •  <a href="/wiki/Karboksiciklopropilglicin" title="Karboksiciklopropilglicin">CCG</a> •  <a href="/wiki/Cikloserin" title="Cikloserin">Cikloserin</a> •  <a href="/wiki/N-(3,3-Difenilpropil)glicinamid" title="N-(3,3-Difenilpropil)glicinamid">DHPG</a> •  <a href="/wiki/Fluoroalanin" title="Fluoroalanin">Fluoroalanin</a> •  <a href="/wiki/%D0%93%D0%BB%D0%B8%D1%86%D0%B8%D0%BD" title="Глицин">Glicin</a> •  <a href="/wiki/HA-966" title="HA-966">HA-966</a> •  <a href="/wiki/L-687,414" title="L-687,414">L-687,414</a> •  <a href="/wiki/Milacemid" title="Milacemid">Milacemid</a> •  <a href="/wiki/Sarkozin" title="Sarkozin">Sarkozin</a> •  <a href="/wiki/Serin" title="Serin">Serin</a> •  <a href="/wiki/Tetrazolilglicin" title="Tetrazolilglicin">Tetrazolilglicin</a>; <i>Agonisti poliaminskog mesta:</i> <a href="/wiki/Akamprosat" title="Akamprosat">Akamprosat</a> •  <a href="/wiki/Spermidin" title="Spermidin">Spermidin</a> •  <a href="/wiki/Spermin" title="Spermin">Spermin</a><br /><b><a href="/wiki/NMDA_receptor_antagonist" class="mw-redirect" title="NMDA receptor antagonist">Antagonisti</a>:</b> <i>Konkurentni antagonisti:</i> <a href="/wiki/AP5" title="AP5">AP5 (APV)</a> •  <a href="/wiki/AP-7_(drug)" class="mw-redirect" title="AP-7 (drug)">AP7</a> •  <a href="/wiki/CGP-37849" title="CGP-37849">CGP-37849</a> •  <a href="/wiki/CGP-39551" title="CGP-39551">CGP-39551</a> •  <a href="/wiki/CGP-39653" title="CGP-39653">CGP-39653</a> •  <a href="/wiki/CGP-40116" class="mw-redirect" title="CGP-40116">CGP-40116</a> •  <a href="/wiki/CGS-19755" class="mw-redirect" title="CGS-19755">CGS-19755</a> •  <a href="/wiki/3-(2-karboksipiperazin-4-yl)propil-1-fosfonska_kiselina" class="mw-redirect" title="3-(2-karboksipiperazin-4-yl)propil-1-fosfonska kiselina">CPP</a> •  <a href="/wiki/LY-233,053" title="LY-233,053">LY-233,053</a> •  <a href="/wiki/LY-235,959" title="LY-235,959">LY-235,959</a> •  <a href="/wiki/LY-274,614" class="mw-redirect" title="LY-274,614">LY-274,614</a> •  <a href="/wiki/MDL-100,453" title="MDL-100,453">MDL-100,453</a> •  <a href="/wiki/Midafotel" title="Midafotel">Midafotel (d-CPPen)</a> •  <a href="/wiki/NPC-12,626" title="NPC-12,626">NPC-12,626</a> •  <a href="/wiki/NPC-17,742" title="NPC-17,742">NPC-17,742</a> •  <a href="/wiki/PBPD" class="mw-redirect" title="PBPD">PBPD</a> •  <a href="/wiki/PEAQX" title="PEAQX">PEAQX</a> •  <a href="/wiki/Perzinfotel" title="Perzinfotel">Perzinfotel</a> •  <a href="/wiki/Cis-1-(fenantren-2-karbonil)piperazin-2,3-dikarboksilna_kiselina" title="Cis-1-(fenantren-2-karbonil)piperazin-2,3-dikarboksilna kiselina">PPDA</a> •  <a href="/wiki/SDZ-220581" title="SDZ-220581">SDZ-220581</a> •  <a href="/wiki/Selfotel" title="Selfotel">Selfotel</a>; <i>Nekonkurentni antagonisti:</i> <a href="/wiki/ARR-15,896" class="mw-redirect" title="ARR-15,896">ARR-15,896</a> •  <a href="/wiki/Karoverin" title="Karoverin">Karoverin</a> •  <a href="/wiki/Deksanabinol" title="Deksanabinol">Deksanabinol</a> •  <a href="/wiki/FPL-12495" title="FPL-12495">FPL-12495</a> •  <a href="/wiki/FR-115,427" title="FR-115,427">FR-115,427</a> •  <a href="/wiki/Hodgkinsin" class="mw-redirect" title="Hodgkinsin">Hodgkinsin</a> •  <a href="/wiki/%D0%9C%D0%B0%D0%B3%D0%BD%D0%B5%D0%B7%D0%B8%D1%98%D1%83%D0%BC" title="Магнезијум">Magnezijum</a> •  <a href="/wiki/MDL-27,266" title="MDL-27,266">MDL-27,266</a> •  <a href="/wiki/NPS-1506" class="mw-redirect" title="NPS-1506">NPS-1506</a> •  <a href="/wiki/Psihotridin" title="Psihotridin">Psihotridin</a> •  <a href="/wiki/%D0%A6%D0%B8%D0%BD%D0%BA" title="Цинк">Cink</a>; <i>Nekonkurentni blokatori pora:</i> <a href="/wiki/2-MDP" title="2-MDP">2-MDP</a> •  <a href="/wiki/3-MeO-PCP" title="3-MeO-PCP">3-MeO-PCP</a> •  <a href="/wiki/8a-Fenildekahidrokinolin" class="mw-redirect" title="8a-Fenildekahidrokinolin">8A-PDHQ</a> •  <a href="/wiki/Amantadin" title="Amantadin">Amantadin</a> •  <a href="/wiki/Aptiganel" title="Aptiganel">Aptiganel</a> •  <a href="/wiki/ARL-12,495" class="mw-redirect" title="ARL-12,495">ARL-12,495</a> •  <a href="/wiki/ARL-15,896-AR" class="mw-redirect" title="ARL-15,896-AR">ARL-15,896-AR</a> •  <a href="/wiki/ARL-16,247" class="mw-redirect" title="ARL-16,247">ARL-16,247</a> •  <a href="/wiki/Budipin" title="Budipin">Budipin</a> •  <a href="/wiki/Delucemin" title="Delucemin">Delucemin</a> •  <a href="/wiki/Deksoksadrol" title="Deksoksadrol">Deksoksadrol</a> •  <a href="/wiki/Dekstralorfan" title="Dekstralorfan">Dekstralorfan</a> •  <a href="/wiki/Dieticiklidin" title="Dieticiklidin">Dieticiklidin</a> •  <a href="/wiki/Dizocilpin" title="Dizocilpin">Dizocilpin</a> •  <a href="/wiki/Endopsihozin" class="mw-redirect" title="Endopsihozin">Endopsihozin</a> •  <a href="/wiki/Esketamin" title="Esketamin">Esketamin</a> •  <a href="/wiki/Etoksadrol" title="Etoksadrol">Etoksadrol</a> •  <a href="/wiki/Eticiklidin" title="Eticiklidin">Eticiklidin</a> •  <a href="/wiki/Gaciklidin" title="Gaciklidin">Gaciklidin</a> •  <a href="/wiki/Ibogain" title="Ibogain">Ibogain</a> •  <a href="/wiki/Indantadol" title="Indantadol">Indantadol</a> •  <a href="/wiki/%D0%9A%D0%B5%D1%82%D0%B0%D0%BC%D0%B8%D0%BD" title="Кетамин">Ketamin</a> •  <a href="/wiki/Ketobemidon" title="Ketobemidon">Ketobemidon</a> •  <a href="/wiki/Loperamid" title="Loperamid">Loperamid</a> •  <a href="/wiki/Memantin" title="Memantin">Memantin</a> •  <a href="/wiki/Meperidin" class="mw-redirect" title="Meperidin">Meperidin (Petidin)</a> •  <a href="/wiki/%D0%9C%D0%B5%D1%82%D0%B0%D0%B4%D0%BE%D0%BD" title="Метадон">Metadon</a> •  <a href="/wiki/Metorfan" title="Metorfan">Metorfan</a> (<a href="/wiki/Dekstrometorfan" title="Dekstrometorfan">Dekstrometorfan</a>, <a href="/wiki/Levometorfan" title="Levometorfan">Levometorfan</a>) •  <a href="/wiki/Metoksetamin" title="Metoksetamin">Metoksetamin</a> •  <a href="/wiki/Milnacipran" title="Milnacipran">Milnacipran</a> •  <a href="/wiki/Morfanol" class="mw-redirect" title="Morfanol">Morfanol</a> (<a href="/wiki/Dekstrorfan" title="Dekstrorfan">Dekstrorfan</a>, <a href="/wiki/Levorfanol" title="Levorfanol">Levorfanol</a>) •  <a href="/wiki/NEFA_(drug)" class="mw-redirect" title="NEFA (drug)">NEFA</a> •  <a href="/wiki/Nerameksan" title="Nerameksan">Nerameksan</a> •  <a href="/wiki/%D0%90%D0%B7%D0%BE%D1%82%D1%81%D1%83%D0%B1%D0%BE%D0%BA%D1%81%D0%B8%D0%B4" class="mw-redirect" title="Азотсубоксид">Azotsuboksid</a> •  <a href="/wiki/Noribogain" title="Noribogain">Noribogain</a> •  <a href="/wiki/Orfenadrin" title="Orfenadrin">Orfenadrin</a> •  <a href="/wiki/PCPr" class="mw-redirect" title="PCPr">PCPr</a> •  <a href="/wiki/Fenciklamin" title="Fenciklamin">Fenciklamin</a> •  <a href="/wiki/%D0%A4%D0%B5%D0%BD%D1%86%D0%B8%D0%BA%D0%BB%D0%B8%D0%B4%D0%B8%D0%BD" title="Фенциклидин">Fenciklidin</a> •  <a href="/wiki/Propoksifen" class="mw-redirect" title="Propoksifen">Propoksifen</a> •  <a href="/wiki/Remacemid" title="Remacemid">Remacemid</a> •  <a href="/wiki/Rinhofilin" title="Rinhofilin">Rinhofilin</a> •  <a href="/wiki/Riluzol" title="Riluzol">Riluzol</a> •  <a href="/wiki/Rimantadin" title="Rimantadin">Rimantadin</a> •  <a href="/wiki/Roliciklidin" title="Roliciklidin">Roliciklidin</a> •  <a href="/wiki/Sabeluzol" title="Sabeluzol">Sabeluzol</a> •  <a href="/wiki/Tenociklidin" title="Tenociklidin">Tenociklidin</a> •  <a href="/wiki/Tiletamin" title="Tiletamin">Tiletamin</a> •  <a href="/wiki/%D0%A2%D1%80%D0%B0%D0%BC%D0%B0%D0%B4%D0%BE%D0%BB" title="Трамадол">Tramadol</a> •  <a href="/wiki/%D0%9A%D1%81%D0%B5%D0%BD%D0%BE%D0%BD" title="Ксенон">Ksenon</a>; <i>Antagonisti glicinskog mesta:</i> <a href="/wiki/ACEA-1021" class="mw-redirect" title="ACEA-1021">ACEA-1021</a> •  <a href="/wiki/ACEA-1328" title="ACEA-1328">ACEA-1328</a> •  <a href="/wiki/Karisoprodol" title="Karisoprodol">Karisoprodol</a> •  <a href="/wiki/CGP-39653" title="CGP-39653">CGP-39653</a> •  <a href="/wiki/7-hlorokinurenat" class="mw-redirect" title="7-hlorokinurenat">CKA</a> •  <a href="/wiki/DCKA" class="mw-redirect" title="DCKA">DCKA</a> •  <a href="/wiki/Felbamat" title="Felbamat">Felbamat</a> •  <a href="/wiki/Gavestinel" title="Gavestinel">Gavestinel</a> •  <a href="/wiki/GV-196,771" title="GV-196,771">GV-196,771</a> •  <a href="/wiki/Kinurenska_kiselina" title="Kinurenska kiselina">Kinurenska kiselina</a> •  <a href="/wiki/L-689,560" title="L-689,560">L-689,560</a> •  <a href="/wiki/L-701,324" title="L-701,324">L-701,324</a> •  <a href="/wiki/Lakosamid" title="Lakosamid">Lakosamid</a> •  <a href="/wiki/Likostinel" title="Likostinel">Likostinel</a> •  <a href="/wiki/LU-73,068" title="LU-73,068">LU-73,068</a> •  <a href="/wiki/MDL-105,519" title="MDL-105,519">MDL-105,519</a> •  <a href="/wiki/Meprobamat" title="Meprobamat">Meprobamat</a> •  <a href="/wiki/MRZ_2/576" title="MRZ 2/576">MRZ 2/576</a> •  <a href="/wiki/PNQX" title="PNQX">PNQX</a> •  <a href="/wiki/ZD-9379" title="ZD-9379">ZD-9379</a>; <i>Antagonisti NR2B podjedinice:</i> <a href="/wiki/Bezonprodil" class="mw-redirect" title="Bezonprodil">Bezonprodil</a> •  <a href="/wiki/CO-101,244" title="CO-101,244">CO-101,244 (PD-174,494)</a> •  <a href="/wiki/CP-101,606" class="mw-redirect" title="CP-101,606">CP-101,606</a> •  <a href="/wiki/Eliprodil" title="Eliprodil">Eliprodil</a> •  <a href="/wiki/Haloperidol" title="Haloperidol">Haloperidol</a> •  <a href="/wiki/Ifenprodil" title="Ifenprodil">Ifenprodil</a> •  <a href="/wiki/Izoksuprin" title="Izoksuprin">Izoksuprin</a> •  <a href="/wiki/Nilidrin" class="mw-redirect" title="Nilidrin">Nilidrin</a> •  <a href="/wiki/Ro8-4304" title="Ro8-4304">Ro8-4304</a> •  <a href="/wiki/Ro25-6981" title="Ro25-6981">Ro25-6981</a> •  <a href="/wiki/Traksoprodil" title="Traksoprodil">Traksoprodil</a>; <i>Neklasifikovani/nesortirani antagonisti:</i> <a href="/wiki/%D0%A5%D0%BB%D0%BE%D1%80%D0%BE%D1%84%D0%BE%D1%80%D0%BC" title="Хлороформ">Hloroform</a> •  <a href="/wiki/Dietil_etar" title="Dietil etar">Dietil etar</a> •  <a href="/wiki/Enfluran" title="Enfluran">Enfluran</a> •  <a href="/wiki/%D0%95%D1%82%D0%B0%D0%BD%D0%BE%D0%BB" title="Етанол">Etanol (Alkohol)</a> •  <a href="/wiki/Halotan" title="Halotan">Halotan</a> •  <a href="/wiki/Izofluran" title="Izofluran">Izofluran</a> •  <a href="/wiki/Metoksifluran" title="Metoksifluran">Metoksifluran</a> •  <a href="/wiki/Toluen" title="Toluen">Toluen</a> •  <a href="/wiki/1,1,1-Trihloroetan" title="1,1,1-Trihloroetan">Trihloroetan</a> •  <a href="/wiki/2,2,2-Trihloroetanol" title="2,2,2-Trihloroetanol">Trihloroetanol</a> •  <a href="/wiki/Trihloroetilen" title="Trihloroetilen">Trihloroetilen</a> •  <a href="/wiki/%D0%9A%D1%81%D0%B8%D0%BB%D0%B5%D0%BD" title="Ксилен">Ksilen</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/Kainatni_receptor" title="Kainatni receptor">Kainat</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><b>Agonisti:</b> <a href="/wiki/5-Jodovilardin" title="5-Jodovilardin">5-Jodovilardin</a> •  <a href="/wiki/ATPA" title="ATPA">ATPA</a> •  <a href="/wiki/Domoi%C4%8Dna_kiselina" class="mw-redirect" title="Domoična kiselina">Domoična kiselina</a> •  <a href="/wiki/Kainska_kiselina" title="Kainska kiselina">Kainska kiselina</a> •  <a href="/wiki/LY-339,434" title="LY-339,434">LY-339,434</a> •  <a href="/wiki/SYM-2081" title="SYM-2081">SYM-2081</a><br /><b>Antagonisti:</b> <a href="/wiki/CNQX" title="CNQX">CNQX</a> •  <a href="/wiki/DNQX" class="mw-redirect" title="DNQX">DNQX</a> •  <a href="/wiki/LY-382,884" title="LY-382,884">LY-382,884</a> •  <a href="/wiki/NBQX" title="NBQX">NBQX</a> •  <a href="/wiki/NS102" title="NS102">NS102</a> •  <a href="/wiki/UBP-302" title="UBP-302">UBP-302</a>; <i>Negativni alosterni modulatori:</i> <a href="/wiki/NS-3763" title="NS-3763">NS-3763</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/Metabotropni_glutamatni_receptor" title="Metabotropni glutamatni receptor">Metabotropni</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/Metabotropni_glutamatni_receptor" title="Metabotropni glutamatni receptor">Grupa I</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><b>Agonisti:</b> <i>Neselektivni</i>: <a href="/wiki/ACPD" title="ACPD">ACPD</a> •  <a href="/wiki/Dihidroksifenilglicin" title="Dihidroksifenilglicin">DHPG</a> •  <a href="/wiki/Kuiskualinska_kiselina" title="Kuiskualinska kiselina">Kuiskualinska kiselina</a>; <i>mGlu1-selektivni</i>: <a href="/wiki/Ro01-6128" title="Ro01-6128">Ro01-6128</a> •  <a href="/wiki/Ro67-4853" title="Ro67-4853">Ro67-4853</a> •  <a href="/wiki/Ro67-7476" title="Ro67-7476">Ro67-7476</a> •  <a href="/wiki/VU-71" title="VU-71">VU-71</a>; <i>mGlu5-selektivni</i>: <a href="/wiki/ADX-47273" title="ADX-47273">ADX-47273</a> •  <a href="/wiki/CDPPB" title="CDPPB">CDPPB</a> •  <a href="/wiki/CHPG" class="mw-redirect" title="CHPG">CHPG</a> •  <a href="/wiki/1-(3-fluorofenil)-N-((3-fluorofenil)metilideneamino)metanimin" title="1-(3-fluorofenil)-N-((3-fluorofenil)metilideneamino)metanimin">DFB</a> •  <a href="/wiki/VU-1545" title="VU-1545">VU-1545</a><br /><b>Antagonisti:</b> <i>Neselektivni</i>: <a href="/wiki/MCPG" class="mw-redirect" title="MCPG">MCPG</a> •  <a href="/wiki/NPS-2390" title="NPS-2390">NPS-2390</a>; <i>mGlu1-selektivni</i>: <a href="/wiki/BAY_36-7620" title="BAY 36-7620">BAY 36-7620</a> •  <a href="/wiki/CPCCOEt" title="CPCCOEt">CPCCOEt</a> •  <a href="/wiki/LY-367,385" title="LY-367,385">LY-367,385</a> •  <a href="/wiki/LY-456,236" title="LY-456,236">LY-456,236</a>; <i>mGlu5-selektivni</i>: <a href="/wiki/DMeOB" title="DMeOB">DMeOB</a> •  <a href="/wiki/Fenobam" title="Fenobam">Fenobam</a> •  <a href="/wiki/LY-344,545" title="LY-344,545">LY-344,545</a> •  <a href="/wiki/2-Metil-6-(feniletinil)piridin" title="2-Metil-6-(feniletinil)piridin">MPEP</a> •  <a href="/wiki/MTEP" title="MTEP">MTEP</a> •  <a href="/wiki/SIB-1757" title="SIB-1757">SIB-1757</a> •  <a href="/wiki/SIB-1893" title="SIB-1893">SIB-1893</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/Metabotropni_glutamatni_receptor" title="Metabotropni glutamatni receptor">Grupa II</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><b>Agonisti:</b> <i>Neselektivni:</i> <a href="/wiki/CBiPES" title="CBiPES">CBiPES</a> •  <a href="/wiki/DCG-IV" title="DCG-IV">DCG-IV</a> •  <a href="/wiki/Eglumegad" title="Eglumegad">Eglumegad</a> •  <a href="/wiki/LY-379,268" title="LY-379,268">LY-379,268</a> •  <a href="/wiki/LY-404,039" title="LY-404,039">LY-404,039</a> •  <a href="/wiki/LY-487,379" title="LY-487,379">LY-487,379</a> •  <a href="/wiki/MGS-0028" title="MGS-0028">MGS-0028</a>; <i>mGlu2-selektivni:</i> <a href="/wiki/Bifenilindanon_A" title="Bifenilindanon A">BINA</a> •  <a href="/wiki/LY-566,332" class="mw-redirect" title="LY-566,332">LY-566,332</a><br /><b>Antagonisti:</b> <i>Neselektivni:</i> <a href="/wiki/APICA_(lek)" title="APICA (lek)">APICA</a> •  <a href="/wiki/EGLU" title="EGLU">EGLU</a> •  <a href="/wiki/HYDIA" title="HYDIA">HYDIA</a> •  <a href="/wiki/LY-307,452" title="LY-307,452">LY-307,452</a> •  <a href="/wiki/LY-341,495" title="LY-341,495">LY-341,495</a> •  <a href="/wiki/MCPG" class="mw-redirect" title="MCPG">MCPG</a> •  <a href="/wiki/MGS-0039" title="MGS-0039">MGS-0039</a>; <i>mGlu2-selektivni:</i> <a href="/wiki/PCCG-4" title="PCCG-4">PCCG-4</a>; <i>mGlu3-selektivni:</i> <a href="/wiki/CECXG" title="CECXG">CECXG</a>; <i>Negativni alosterni modulatori:</i> <a href="/wiki/RO4491533" title="RO4491533">RO4491533</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/Metabotropni_glutamatni_receptor" title="Metabotropni glutamatni receptor">Grupa III</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><b>Agonisti:</b> <i>Neselektivni:</i> <a href="/wiki/L-AP4" title="L-AP4">L-AP4</a>; <i>mGlu4-selektivni:</i> <a href="/wiki/PHCCC" title="PHCCC">PHCCC</a> •  <a href="/wiki/VU-001,171" title="VU-001,171">VU-001,171</a> •  <a href="/wiki/VU-0155,041" title="VU-0155,041">VU-0155,041</a>; <i>mGlu7-selektivni:</i> <a href="/wiki/AMN082" title="AMN082">AMN082</a>; <i>mGlu8-selektivni:</i> <a href="/wiki/DCPG" title="DCPG">DCPG</a><br /><b>Antagonisti:</b> <i>Neselektivni:</i> <a href="/wiki/2-Amino-2-ciklopropil-2-(4-fosfonofenil)sir%C4%87etna_kiselina" title="2-Amino-2-ciklopropil-2-(4-fosfonofenil)sirćetna kiselina">CPPG</a> •  <a href="/wiki/MAP4_(lek)" class="mw-redirect" title="MAP4 (lek)">MAP4</a> •  <a href="/wiki/MSOP_(lek)" class="mw-redirect" title="MSOP (lek)">MSOP</a> •  <a href="/wiki/MPPG" class="mw-redirect" title="MPPG">MPPG</a> •  <a href="/wiki/MTPG" class="mw-redirect" title="MTPG">MTPG</a> •  <a href="/wiki/UBP-1112" title="UBP-1112">UBP-1112</a>; <i>mGlu7-selektivni:</i> <a href="/wiki/MMPIP" title="MMPIP">MMPIP</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/Inhibitor_reapsorpcije" class="mw-redirect" title="Inhibitor reapsorpcije">Inhibitori</a><br /><a href="/wiki/Glutamatni_transporter" class="mw-redirect" title="Glutamatni transporter">transporta</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/Glutamatni_transporter" class="mw-redirect" title="Glutamatni transporter">EAAT</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Dihidrokainska_kiselina" title="Dihidrokainska kiselina">DHKA</a> •  <a href="/wiki/L-trans-Pirolidin-2,4-dikarboksilna_kiselina" title="L-trans-Pirolidin-2,4-dikarboksilna kiselina">PDC</a> •  <a href="/wiki/WAY-213,613" title="WAY-213,613">WAY-213,613</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background: LightYellow"><a href="/wiki/Vezikularnu_glutamatni_transporteri" class="mw-redirect" title="Vezikularnu glutamatni transporteri">vGluT</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/7-%D0%A5%D0%BB%D0%BE%D1%80%D0%BE%D0%BA%D0%B8%D0%BD%D1%83%D1%80%D0%B5%D0%BD%D1%81%D0%BA%D0%B0_%D0%BA%D0%B8%D1%81%D0%B5%D0%BB%D0%B8%D0%BD%D0%B0" title="7-Хлорокинуренска киселина">7-CKA</a> •  <a href="/wiki/Evansovo_plavo" class="mw-redirect" title="Evansovo plavo">Evansovo plavo</a></div></td></tr></tbody></table><div></div></td></tr></tbody></table></div>    </div><noscript><img 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