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Major Programs | Division of Cancer Prevention

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<nav class="navbar" id="navbar-top"> <div class="container"> <section class="row region region-logo-section"> <a href="/" title="Home" rel="home" class="navbar-brand"> <img src="https://prevention.cancer.gov/themes/custom/custom_base_theme/siteLogo.png" alt="Home" class="img-fluid d-inline-block align-top" /> <div class="sr-only">Division of Cancer Prevention</div> </a> </section> <section class="row region region-top-header"> <div id="block-thunderstonesearchbox" class="block-content-basic block block-block-content block-block-content251f5f2d-e6b6-4f48-bd5e-79f0c0fc84e7"> <div class="content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><form class="searchbox search-form search-block-form form-row" name="form1" method="get" action="/search" id="search-block-form"> <fieldset class="js-form-item js-form-type-search form-type-search js-form-item-keys form-item-keys form-no-label form-group"> <label 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class="sf-depth-2">Alliance of Glycobiologists for Cancer Research</a></li><li id="main-menu-link-content95066f34-2f24-4e8b-a69a-67f8c981b4b8" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="cancer-immunoprevention-network-cip-net_child" data-modstate="modstate-"><a href="/major-programs/cancer-immunoprevention-network-cip-net" class="sf-depth-2">Cancer Immunoprevention Network (CIP-Net)</a></li><li id="main-menu-link-contentb23b3271-1024-4d3a-98ef-d91635feeaeb" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="cancer-prevention-clinical-trials-network-cp-ctnet_child" data-modstate="modstate-"><a href="/major-programs/cancer-prevention-clinical-trials-network-cp-ctnet" class="sf-depth-2">Cancer Prevention Clinical Trials Network (CP-CTNet)</a></li><li id="main-menu-link-content046e53c7-945b-4964-8ae0-df5cc4fadb2a" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="cancer-prevention-fellowship-program-cpfp_child" data-modstate="modstate-"><a 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sf-clone-parent sf-no-children" data-title="cancer-treatment-tolerability-consortium_child" data-modstate="modstate-"><a href="/major-programs/cancer-treatment-tolerability-consortium" class="sf-depth-2">Cancer Treatment Tolerability Consortium</a></li><li id="main-menu-link-content6c4e49ef-a758-4301-8a1c-4a90057acbdd" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="consortium-for-imaging-and-biomarkers-cib_child" data-modstate="modstate-"><a href="/major-programs/consortium-imaging-and-biomarkers-cib" class="sf-depth-2">Consortium for Imaging and Biomarkers (CIB)</a></li><li id="main-menu-link-contenta24c0b8f-678c-4cd4-a967-0a49d802543a" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="discovery-and-development-of-natural-products-for-cancer-interception-and-prevention-ddnp-cip_child" data-modstate="modstate-"><a href="/major-programs/discovery-and-development-natural-products-cancer-interception-and-prevention-ddnp" class="sf-depth-2">Discovery and Development of Natural Products for Cancer Interception and Prevention (DDNP-CIP)</a></li><li id="main-menu-link-content7202d751-4043-40a0-8a1b-f6303f367d95" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="early-detection-research-network-edrn_child" data-modstate="modstate-"><a href="/major-programs/early-detection-research-network-edrn" class="sf-depth-2">Early Detection Research Network (EDRN)</a></li><li id="main-menu-link-contentc246bc5a-912f-46f8-ae26-944a737c7307" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="hiv-cervical-cancer-prevention-‘cascade’-clinical-trials-network_child" data-modstate="modstate-"><a href="/major-programs/hivcervical-cancer-prevention-cascade-clinical-trials-network" class="sf-depth-2">HIV/Cervical Cancer Prevention ‘CASCADE’ Clinical Trials Network</a></li><li id="main-menu-link-content958c16e8-d85b-48f7-8f18-8ffb45a8236d" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="liquid-biopsy-consortium_child" data-modstate="modstate-"><a href="/major-programs/liquid-biopsy-consortium" class="sf-depth-2">Liquid Biopsy Consortium</a></li><li id="main-menu-link-content0085a339-9a09-4888-bd21-1b1eb1d44636" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="lung-cancer-screening-image-library_child" data-modstate="modstate-"><a href="/major-programs/lung-cancer-screening-image-library" class="sf-depth-2">Lung Cancer Screening Image Library</a></li><li id="main-menu-link-content2691dee7-cf01-4f03-b6ef-b33559f02d20" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="multi-cancer-detection-mcd-research_child" data-modstate="modstate-"><a href="/major-programs/multi-cancer-detection-mcd-research" class="sf-depth-2">Multi-Cancer Detection (MCD) Research</a></li><li id="main-menu-link-content8f15d63c-1f0c-4442-982d-2ca4337e30f6" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="nci-cervical-cancer-‘last-mile’-initiative_child" data-modstate="modstate-"><a href="/major-programs/nci-cervical-cancer-last-mile-initiative" class="sf-depth-2">NCI Cervical Cancer ‘Last Mile’ Initiative</a></li><li id="main-menu-link-contentb89054c9-6b64-458b-9e67-c0e640a84044" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="nci-community-oncology-research-program-ncorp_child" data-modstate="modstate-"><a href="/major-programs/nci-community-oncology-research-program-ncorp" class="sf-depth-2">NCI Community Oncology Research Program (NCORP)</a></li><li id="main-menu-link-content19cf16f5-1d6c-4e5f-8f46-08b90d25216c" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="pancreatic-cancer-detection-consortium-pcdc_child" data-modstate="modstate-"><a href="/major-programs/pancreatic-cancer-detection-consortium-pcdc" class="sf-depth-2">Pancreatic Cancer Detection Consortium (PCDC)</a></li><li id="main-menu-link-contentd3cf0fc2-69cc-44c8-beed-fc2fea2cead6" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="pre-cancer-atlas-pca_child" data-modstate="modstate-"><a href="/major-programs/pre-cancer-atlas-pca" class="sf-depth-2">Pre-Cancer Atlas (PCA)</a></li><li id="main-menu-link-content68abbf31-af00-42e0-8201-abc3c7ecfd45" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="prevent-cancer-preclinical-drug-development-program-prevent_child" data-modstate="modstate-"><a href="/major-programs/prevent-cancer-preclinical-drug-development-program-prevent" class="sf-depth-2">PREVENT Cancer Preclinical Drug Development Program (PREVENT)</a></li><li id="main-menu-link-content4638ae44-de1a-464b-88ca-13cd2ed64225" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="prostate-lung-colorectal-and-ovarian-cancer-screening-trial-plco_child" data-modstate="modstate-"><a href="/major-programs/prostate-lung-colorectal-and-ovarian-cancer-screening-trial-plco" class="sf-depth-2">Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO)</a></li><li id="main-menu-link-content89320c74-a77c-4bb8-bd35-20d3db95ad78" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="supportive-care-and-symptom-management_child" data-modstate="modstate-"><a href="/major-programs/supportive-care-and-symptom-management" class="sf-depth-2">Supportive Care and Symptom Management</a></li><li id="main-menu-link-content8cad61e8-21e4-4054-9bd8-d708b7284ddb" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="translational-and-basic-science-research-in-early-lesions-tbel-program_child" data-modstate="modstate-"><a href="/major-programs/translational-and-basic-science-research-early-lesions-tbel-program" class="sf-depth-2">Translational and Basic Science Research in Early Lesions (TBEL) Program</a></li><li id="main-menu-link-contenteb96a8c5-5b50-4a8c-bfe5-98a67ba4e0a9" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="translational-liver-cancer-tlc-consortium_child" data-modstate="modstate-"><a href="/major-programs/translational-liver-cancer-tlc-consortium" class="sf-depth-2">Translational Liver Cancer (TLC) Consortium</a></li><li id="main-menu-link-contentf578bd5e-0bd7-4e66-9cec-e58e64af261b" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="us-latin-american-caribbean-hiv-hpv-cancer-prevention-clinical-trials-network-ulacnet_child" data-modstate="modstate-"><a href="/major-programs/us-latin-american-caribbean-hivhpv-cancer-prevention-clinical-trials-network-ulacnet" class="sf-depth-2">US-Latin American-Caribbean HIV/HPV-Cancer Prevention Clinical Trials Network (ULACNet)</a></li></ul></li><li id="main-menu-link-contentf0d78abe-0e3b-42fe-a2cc-7ed1af974de7" class="sf-depth-1 menuparent" data-title="research-groups_parent" data-modstate="modstate-"><a href="/research-groups" class="sf-depth-1 menuparent">Research Groups</a><ul><li id="main-menu-link-contentf0d78abe-0e3b-42fe-a2cc-7ed1af974de7--2" class="sf-depth-1 sf-clone-parent sf-no-children" 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class="sf-depth-2 sf-clone-parent sf-no-children" data-title="gastrointestinal-and-other-cancers_child" data-modstate="modstate-"><a href="/research-groups/gastrointestinal-and-other-cancers" class="sf-depth-2">Gastrointestinal and Other Cancers</a></li><li id="main-menu-link-contentb3971e4e-6eee-4357-a81a-be9d3ef21d26" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="lung-and-upper-aerodigestive-cancer_child" data-modstate="modstate-"><a href="/research-groups/lung-and-upper-aerodigestive-cancer" class="sf-depth-2">Lung and Upper Aerodigestive Cancer</a></li><li id="main-menu-link-contentc5ea769e-725d-45b8-bc95-e6d162fae7b6" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="nutritional-science_child" data-modstate="modstate-"><a href="/research-groups/nutritional-science" class="sf-depth-2">Nutritional Science</a></li><li id="main-menu-link-contentfafa3008-bd1f-4f2b-81af-60332becb795" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="prostate-and-urologic-cancer_child" data-modstate="modstate-"><a href="/research-groups/prostate-and-urologic-cancer" class="sf-depth-2">Prostate and Urologic Cancer</a></li></ul></li><li id="main-menu-link-contentde5ae2a3-36c6-4202-b76e-de9704e060a6" class="sf-depth-1 menuparent" data-title="clinical-trials_parent" data-modstate="modstate-"><a href="/clinical-trials" class="sf-depth-1 menuparent">Clinical Trials</a><ul><li id="main-menu-link-contentde5ae2a3-36c6-4202-b76e-de9704e060a6--2" class="sf-depth-1 sf-clone-parent sf-no-children" data-title="clinical-trials_child" data-modstate="modstate-"><a href="/clinical-trials" class="sf-depth-1">Clinical Trials</a></li><li id="main-menu-link-content70bcbc14-12af-492e-8243-d172b9a8f419" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="clinical-trials-search_child" data-modstate="modstate-"><a href="/clinical-trials/clinical-trials-search" title="Search the DCP&#039;s clinical trials database for ongoing clinical trials in prevention, early detection, and the management of symptoms related to cancer and its treatments." class="sf-depth-2">Clinical Trials Search</a></li><li id="main-menu-link-contentf2fecf16-ad86-44b1-85d6-251eddaf5249" class="sf-depth-2 sf-clone-parent sf-no-children" data-title="clinical-trials-management_child" data-modstate="modstate-"><a href="/clinical-trials/clinical-trials-management" class="sf-depth-2">Clinical Trials Management</a></li></ul></li><li id="main-menu-link-content804395ec-0bc0-4579-b932-077c0340d0e3" class="sf-depth-1 menuparent" data-title="funding-amp-grants_parent" data-modstate="modstate-"><a href="/funding-and-grants" class="sf-depth-1 menuparent">Funding &amp; Grants</a><ul><li id="main-menu-link-content804395ec-0bc0-4579-b932-077c0340d0e3--2" class="sf-depth-1 sf-clone-parent sf-no-children" data-title="funding-amp-grants_child" data-modstate="modstate-"><a href="/funding-and-grants" class="sf-depth-1">Funding &amp; Grants</a></li><li 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class="layout-main-wrapper clearfix"> <div id="main" class="container" data-currenturl="https://prevention.cancer.gov/major-programs"> <div id="block-custom-base-theme-breadcrumbs" class="block block-system block-system-breadcrumb-block"> <div class="content"> <nav role="navigation" aria-label="breadcrumb"> <ol class="breadcrumb"> <li class="breadcrumb-item"> <a href="/">Home</a> </li> </ol> </nav> </div> </div> <div class="row row-offcanvas row-offcanvas-left clearfix"> <main class="main-content col" id="content" role="main"> <section class="section"> <a id="main-content" tabindex="-1"></a> <div data-drupal-messages-fallback class="hidden"></div><div id="block-custom-base-theme-page-title" class="block block-core block-page-title-block"> <div class="content"> <h1 class="title"><span class="field field--name-title field--type-string field--label-hidden">Major Programs</span> </h1> </div> </div> <div id="block-custom-base-theme-content" class="block block-system block-system-main-block"> <div class="content"> <article data-history-node-id="13" about="/major-programs" class="node node--type-book node--view-mode-full clearfix"> <header> </header> <div class="node__content clearfix"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The Division of Cancer Prevention supports major scientific collaborations, research networks, investigator-initiated grants, postdoctoral training, and specialized resources across the United States.</p> <h2>&nbsp;</h2></div> <div class="field field--name-field-boxes field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--regular-row paragraph--view-mode--default _5col-20-20-20-20-20"> </div> </div> <div class="field__item"> <div class="paragraph paragraph--type--regular-row paragraph--view-mode--default _5col-20-20-20-20-20"> <div class="field field--name-field-add-a-box field--type-entity-reference-revisions field--label-hidden paragraph--type--columns__28col row field__items"> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/alliance-glycobiologists-cancer-research" data-card-layout="" data-card-height="" data-title="Learn more about the Alliance of Glycobiologists for Cancer Research"> <h2>Alliance of Glycobiologists for Cancer Research</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/glyco-mp.png" width="400" height="266" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>Tumor Glycomics Laboratories work to reveal cancer-related dynamics of complex carbohydrates.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/cancer-immunoprevention-network-cip-net" data-card-layout="" data-card-height="" data-title="Learn more about CIP-Net"> <h2>Cancer Immunoprevention Network (CIP-Net)</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-04/cip-net.jpg" width="300" height="299" typeof="foaf:Image" alt="Wildtype and frameshift mutant Asxl1 mRNA detected by in situ hybridization using RNAScope technology in organoids derived from a mismatch repair-deficient mouse intestinal tumor." /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>This program supports research projects focused on discovery of novel immunoprevention pathways and immune targets.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/cancer-prevention-clinical-trials-network-cp-ctnet" data-card-layout="" data-card-height="" data-title="More about the Cancer Prevention Clinical Trials Network (CP-CTNet)"> <h2> Cancer Prevention Clinical Trials Network (CP-CTNet) </h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2024-03/cp-ctnet-hero.jpg" width="867" height="777" typeof="foaf:Image" alt="A medical professional shakes hands with a patient seated on a examination table." /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>Research Centers develop and conduct early phase clinical trials to assess the preventive potential of agents and interventions of varying classes.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/cancer-prevention-fellowship-program-cpfp" data-card-layout="" data-card-height="" data-title="See more about the Cancer Prevention Fellowship Program (CPFP)"> <h2>Cancer Prevention Fellowship Program (CPFP)</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/fellows-group-photo-2017.jpg" width="400" height="297" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>Advanced training for fellows provides a strong foundation in the field of cancer prevention and control to scientists and clinicians from varied health disciplines.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="no_image" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/cancer-prevention-interception-targeted-agent-discovery-program-cap-it" data-card-layout="" data-card-height="" data-title="More about the Cancer Prevention-Interception Targeted Agent Discovery Program (CAP-IT)"> <h2>Cancer Prevention-Interception Targeted Agent Discovery Program (CAP-IT)</h2> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item">A collaborative research network with the overarching goal of discovering molecularly or immunologically targeted agents designed to prevent or intercept the oncogenic process in higher-risk populations.</div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/cancer-screening-research-network-csrn" data-card-layout="" data-card-height="" data-title="Learn more about CSRN Major Program"> <h2> CSRN Major Program </h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2024-03/CSRN-Overview-Graphic.png" width="2134" height="1683" typeof="foaf:Image" alt="Cancer Screening Research Network Structure" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>As a central component of the&nbsp;Cancer Moonshot<sup>sm</sup>, the National Cancer Institute (NCI) is starting a new&nbsp;<strong>Cancer Screening Research Network (CSRN)</strong>&nbsp;in January 2024 that will conduct trials and studies to systematically evaluate promising and emerging technologies for the purpose of cancer screening.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/cancer-treatment-tolerability-consortium" data-card-layout="" data-card-height="" data-title="Learn more about Cancer Treatment Tolerability Consortium"> <h2>Cancer Treatment Tolerability Consortium</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/Tolerability-Consortium.jpg" width="921" height="487" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>A consortium of multi-disciplinary teams that is developing new methods for analyzing patient-reported outcomes in the setting of cancer clinical trials.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/consortium-imaging-and-biomarkers-cib" data-card-layout="" data-card-height="" data-title="Learn more about the Consortium for Imaging and Biomarkers (CIB)"> <h2>Consortium for Imaging and Biomarkers (CIB)</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/mri-breast.jpg" width="400" height="266" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>Research Units integrate imaging strategies with biomarkers to improve cancer screening, early detection of aggressive cancer, assessment of cancer risk, and diagnosis of early stage cancer.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/discovery-and-development-natural-products-cancer-interception-and-prevention-ddnp" data-card-layout="" data-card-height="" data-title="Learn more about Discovery and Development of Natural Products for Cancer Interception and…"> <h2>Discovery and Development of Natural Products for Cancer Interception and Prevention (DDNP-CIP)</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/cpsb-20230109.jpg" width="940" height="600" typeof="foaf:Image" alt="semi-purified products infographic" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>This supports the discovery and development of novel natural products that are safe, non-toxic, and efficacious for cancer interception and prevention</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/early-detection-research-network-edrn" data-card-layout="" data-card-height="" data-title="More about the Early Detection Research Network (EDRN)"> <h2>Early Detection Research Network (EDRN)</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/edrn-sg.jpg" width="926" height="639" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>Labs and centers bring together comprehensive infrastructure and resources critical to discovery, development and validation of biomarkers for cancer risk and early detection.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="no_image" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/hivcervical-cancer-prevention-cascade-clinical-trials-network" data-card-layout="" data-card-height="" data-title="Learn more about HIV/Cervical Cancer Prevention ‘CASCADE’ Clinical Trials Network"> <h2> HIV/Cervical Cancer Prevention ‘CASCADE’ Clinical Trials Network </h2> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item">Seeks to conduct pragmatic clinical trials evaluating the effectiveness of clinically proven interventions to optimize the cervical cancer screening, management, and precancer treatment cascade for WLWH.</div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/liquid-biopsy-consortium" data-card-layout="" data-card-height="" data-title="Learn more about the Liquid Biopsy Consortium"> <h2>Liquid Biopsy Consortium</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/liquid-biopsy-cropped.jpg" width="400" height="266" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>A partnership with academic and industrial laboratory teams developing noninvasive liquid biopsy techniques to detect early stage cancer from biomarkers in blood, urine and sputum.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/lung-cancer-screening-image-library" data-card-layout="" data-card-height="" data-title="Learn more about Lung Cancer Screening Image Library"> <h2>Lung Cancer Screening Image Library</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/lung-cancer-screening-image-library.jpg" width="440" height="370" typeof="foaf:Image" alt="NCI is creating a Lung Image Library with imaging like these CT scans, for use by Artificial Intelligence researchers to improve lung cancer screening" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>NCI is creating a Lung Image Library for use by Artificial Intelligence researchers to improve lung cancer screening.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/multi-cancer-detection-mcd-research" data-card-layout="" data-card-height="" data-title="Learn more about Multi-Cancer Detection (MCD) Research"> <h2>Multi-Cancer Detection (MCD) Research</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/mced-major-program.png" width="600" height="435" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item">Several assays using different technologies to detect multiple components of a growing cancer are under development for the purpose of detecting cancers at early stages.</div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/nci-cervical-cancer-last-mile-initiative" data-card-layout="" data-card-height="" data-title="More about the NCI Cervical Cancer ‘Last Mile’ Initiative"> <h2>NCI Cervical Cancer ‘Last Mile’ Initiative</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/nci-vol-9718-72.jpg" width="734" height="378" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>A public private partnership between several stakeholders to validate self-collection as a comparable (non-inferior) alternative to provider-collected sampling for HPV testing in cervical cancer screening.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/nci-community-oncology-research-program-ncorp" data-card-layout="" data-card-height="" data-title="Learn more about the NCI Community Oncology Research Program (NCORP)"> <h2>NCI Community Oncology Research Program (NCORP)</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/2019-ncorp-screengrab.PNG" width="1107" height="743" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>A clinical trials network of cancer professionals brings research to diverse populations across the country in the communities where most patients live.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/pancreatic-cancer-detection-consortium-pcdc" data-card-layout="" data-card-height="" data-title="Read more about the Pancreatic Cancer Detection Consortium (PCDC)"> <h2>Pancreatic Cancer Detection Consortium (PCDC)</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/pcdc-logo.jpg" width="400" height="265" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>Research teams develop and test new molecular and imaging biomarkers to detect early stage pancreatic ductal adenocarcinoma and its precursor lesions.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="no_image" data-card-height="cardheight-short"> <a class="hover-box d-block node--type-research-area" href="/major-programs/pre-cancer-atlas-pca" data-card-layout="" data-title="Pre-Cancer Atlas (PCA)"> <h2><span class="field field--name-title field--type-string field--label-hidden">Pre-Cancer Atlas (PCA)</span> </h2> <span class="box-img-wrapper float-right ml-2 mb-2"></span> <div class="box-body-wrapper"><p>The <strong>Pre-cancer Atlas (PCA) Research Centers</strong> are one of the three scientific components of the Human Tumor Atlas Network (HTAN). HTAN is a collaborative research initiative for constructing 3-dimensional (3-D) and dynamic atlases of the cellular, morphological, molecular, and…</div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/prevent-cancer-preclinical-drug-development-program-prevent" data-card-layout="" data-card-height="" data-title="Read more about the PREVENT Cancer Preclinical Drug Development Program (PREVENT)"> <h2>PREVENT Cancer Preclinical Drug Development Program (PREVENT)</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/vo9772.jpg" width="400" height="267" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>The peer-reviewed research pipeline supports new prevention interventions and biomarkers headed toward clinical trials.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="no_image" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/prostate-lung-colorectal-and-ovarian-cancer-screening-trial-plco" data-card-layout="" data-card-height="" data-title="Learn more about the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO)"> <h2>Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO)</h2> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item">A large randomized trial designed to determine the effects of screening on cancer-related mortality and secondary endpoints in people aged 55 to 74. Researchers can request valuable PLCO data and biospecimens.</div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/supportive-care-and-symptom-management" data-card-layout="" data-card-height="" data-title="Read more about Supportive Care and Symptom Management"> <h2>Supportive Care and Symptom Management</h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/supp-care-cropped.jpg" width="400" height="266" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>Clinical trials and grant-funded projects examine symptoms and morbidities related to cancer and its treatment, with a focus on interventions to improve quality of life.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="no_image" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/translational-and-basic-science-research-early-lesions-tbel-program" data-card-layout="" data-card-height="" data-title="Learn more about Translational and Basic Science Research in Early Lesions (TBEL) Program"> <h2>Translational and Basic Science Research in Early Lesions (TBEL) Program</h2> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item">A collaborative research network that aims to further understand the biological and pathophysiological mechanisms and to facilitate biology-backed precision prevention approaches.</div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="all_content" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/translational-liver-cancer-tlc-consortium" data-card-layout="" data-card-height="" data-title="Learn more about the Translational Liver Cancer (TLC) Consortium"> <h2> Translational Liver Cancer (TLC) Consortium </h2> <span class="box-img-wrapper float-right ml-2 mb-2"> <div class="field field--name-field-card-image field--type-entity-reference field--label-hidden field__item"><div media-view-mode="default"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/sites/default/files/2023-02/mp-tlc.jpg" width="400" height="266" typeof="foaf:Image" alt="" /> </div> </div></div> </span> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item"><p>Five Translational Research Centers conduct studies to improve surveillance of liver cancer in high-risk populations, increase detectability at early stages, and stratify at-risk patients.</p></div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--link-box-dcp-pages paragraph--view-mode--default box-color-medium-blue btn--color--"> <span data-card-layout="no_image" data-card-height="cardheight-short"> <a class="hover-box d-block type-overwrite-content" href="/major-programs/us-latin-american-caribbean-hivhpv-cancer-prevention-clinical-trials-network-ulacnet" data-card-layout="" data-card-height="" data-title="More about the US-Latin American-Caribbean Clinical Trials Network (ULACNet)"> <h2> US-Latin American-Caribbean HIV/HPV-Cancer Prevention Clinical Trials Network (ULACNet) </h2> <div class="box-body-wrapper"> <div class="clearfix text-formatted field field--name-field-card-body field--type-text-long field--label-hidden field__item">Partnership Centers will focus on improving prevention of human papillomavirus (HPV)-related cancers in human immunodeficiency virus (HIV)-infected individuals.</div> </div> <div style="clear: both;"></div> </a> </span> </div> </div> <div class="field__item d-sm-none d-md-block mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--empty-box paragraph--view-mode--default"> </div> </div> <div class="field__item d-sm-none d-md-block mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--empty-box paragraph--view-mode--default"> </div> </div> <div class="field__item d-sm-none d-md-block mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--empty-box paragraph--view-mode--default"> </div> </div> <div class="field__item d-sm-none d-md-block mw-100" style="flex: 1;"> <div class="paragraph paragraph--type--empty-box paragraph--view-mode--default"> </div> </div> </div> </div> </div> </div> </div> </article> </div> </div> </section> </main> </div> </div> </div> <footer class="site-footer"> <div class="container"> <div class="site-footer__top clearfix"> <section class="row region region-footer-first"> <div id="block-custom-base-theme-footerfollowuslinks" 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