Reassessing Ketorolac | Athletic Training and Sports Health Care

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Several NSAIDs have been studied, but none more recently than ketorolac. Given the several reported adverse outcomes recently linked to ketorolac, we felt a thorough review was necessary. Ketorolac’s most notable side effects "/><meta id="metaKeywords" name="keywords" content="Athletic Training and Sports Health Care,Orthopedics,Health Professions,Sports Medicine,Athletic Training,,Team Physician,"/><meta id="Meta1" name="scID"/><meta id="scID" name="scID"/><meta name="pubabbv" content="ATSHC"/><meta name="authors" content="Craig Yarbrough MD, Daryl A. Rosenbaum MD"/><meta name="articleid" content="{E9C41C06-AEDC-4EB6-BABE-2813564E93CA}"/><meta name="legacyarticleid" content=""/><meta name="article-title" content="Reassessing Ketorolac"/><meta name="article-link" content="/orthopedics/journals/ATSHC/{E9C41C06-AEDC-4EB6-BABE-2813564E93CA}/Reassessing-Ketorolac"/><meta name="doi" content="10.3928/19425864-20130709-12"/><meta name="pubname" content="Athletic Training and Sports Health Care"/><meta name="pubtype" content="print"/><meta name="author" content="Craig Yarbrough, MD"/><meta name="author" content=" Daryl A. 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href="https://web.archive.org/web/20130729065559/http://www.healio.com/orthopedics/journals/atshc/m/past-issues?pissue=a7153412-3169-43fa-9fd3-62b188f2ae6d&year=ee45d327-427a-4a54-9526-1e785d5a1f92">Past Issues</a></li><li><a href="https://web.archive.org/web/20130729065559/http://www.healio.com/orthopedics/arthroscopy/news/print/orthopedics-today/%7Ba23ce958-029f-4667-9a17-2e43a2e29911%7D/intra-articular-ketorolac-reduces-pain-following-acl-surgery">Intra-articular <b>ketorolac</b> reduces pain following ACL surgery <b>...</b></a></li></ul></div> <script language="javascript" type="text/javascript" xmlns:webutil="http://www.sitecore.net/webutil"></script><div class="journals-content" xmlns:webutil="http://www.sitecore.net/webutil"><div class="journal-tab-group"><ul class="journal-tabs"><li><a href="..">Current Issue</a></li><li><a href="/web/20130729065559/http://www.healio.com/orthopedics/journals/ATSHC/m/OAR">Online Advanced Release</a></li><li><a href="/web/20130729065559/http://www.healio.com/orthopedics/journals/ATSHC/m/Past Issues">Past Issues</a></li></ul><div class="journal-panes"><div class="abstract-content"><p class="kicker-top">Team Physician</p><h2><a href="#">Reassessing Ketorolac</a></h2><p class="authors">Craig Yarbrough, MD; Daryl A. Rosenbaum, MD</p><div class="journal-info"><ul class="full-text"><li class="header">Read Full Text Article</li><li class="html"><a class="active" alt="View HTML Version" title="View HTML Version" rel="nofollow" href="/web/20130729065559/http://www.healio.com/buy-journal-or-article?a={E9C41C06-AEDC-4EB6-BABE-2813564E93CA}&returnUrl=%2forthopedics%2fjournals%2fATSHC%2f%7bE9C41C06-AEDC-4EB6-BABE-2813564E93CA%7d%2fReassessing-Ketorolac&jrnl=J0461"> HTML Icon </a></li><li class="pdf"><a class="active" alt="View PDF Version" title="View PDF Version" rel="nofollow" href="/web/20130729065559/http://www.healio.com/buy-journal-or-article?a={E9C41C06-AEDC-4EB6-BABE-2813564E93CA}&returnUrl=%2forthopedics%2fjournals%2fATSHC%2f%7bE9C41C06-AEDC-4EB6-BABE-2813564E93CA%7d%2fReassessing-Ketorolac%3fpdf%3d1&jrnl=J0461"></a></li></ul><ul class="article-citation"><li>Athletic Training and Sports Health Care</li><li>July/August 2013 - Volume 5 · Issue 4: 157-159</li><li class="doi"> DOI: 10.3928/19425864-20130709-12</li></ul></div><div class="copyrights" style="float:right;"><a href="#" onclick="RightsLinkPopUp();"><img src="https://web.archive.org/web/20130729065559im_/http://213a1ca8842e5e699a80-05ce35571e92a3f7383a191aa5840bba.r66.cf1.rackcdn.com/request-permissions.gif" border="0" alt="Rights and Permissions"></a><script language="javascript" type="text/javascript"></script></div><h4>Abstract</h4><p>For several decades, nonsteroidal anti-inflammatories (NSAIDs) have been a mainstay in providing rapid analgesia, decreasing inflammation, and assisting in return to play. Several NSAIDs have been studied, but none more recently than ketorolac. Given the several reported adverse outcomes recently linked to ketorolac, we felt a thorough review was necessary. Ketorolac’s most notable side effects are gastrointestinal problems, acute kidney injury, platelet dysfunction, and, rarely, cardiovascular events. Oral administration of ketorolac shows significant benefit over other routes of administration and includes a 20-minute time of onset, better bioavailability, less cost, and, most importantly, least risk to the player. Ultimately, the use of ketorolac must be under the direct supervision of a physician. Elite players seen in the club house are not different from patients seen in clinic, and a careful history, with proper documentation, and patient education must be performed with every encounter explaining the potential risks and benefits. [<i>Athletic Training & Sports Health Care.</i> 2013;5(4):157–159.]</p><div class="ftAuthorNotes"><p>The authors are from the Department of Family and Community Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.</p><p>The authors have no financial or proprietary interest in the materials presented herein.</p><p>Address correspondence to Craig M. Yarbrough, MD, Resident, HO-II, Department of Family and Community Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157; e-mail: cyarbrou@wakehealth.edu.</p></div><p> doi: 10.3928/19425864-20130709-12</p><p><div class="fb-like" data-href="" data-send="true" data-width="450" data-show-faces="true"></div></p><ul class="share"><li><a href="javascript:void(0)" id="twitter" target="_new">Tweet</a></li><li><a href="javascript:void(0)" id="facebook" target="_new">Share</a></li><li><a href="javascript:void(0)" id="linkedin">Link</a></li><li><span class="db-wrapper"><span class="g-plusone" data-size="tall" data-annotation="none"></span></span></li><li><a href="javascript:void(0)" id="email">Email</a></li><li class="last"><a href="javascript:void(0)" id="print">Print</a></li></ul><div id="respond"><script language="javascript" type="text/javascript"> var idcomments_acct = 'aa6ff53f9870e40f92f83e1b5df3cddf'; var idcomments_post_id = 'e9c41c06-aedc-4eb6-babe-2813564e93ca'; var idcomments_post_url; </script> <span id="IDCommentsPostTitle" style="display: none"></span> <script type="text/javascript" src="https://web.archive.org/web/20130729065559js_/http://www.intensedebate.com/js/genericCommentWrapperV2.js"></script><p class="comment-notes"> Healio is intended for health care provider use and all comments will be posted at the discretion of the editors. 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