CINXE.COM

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class="distributor_region"></div> </div> <div id="search_results" class="col-xs-12 col-sm-4 col-md-9"> <div class="search_mobile_buttons" style="display: none;"> <div class="search_filters_toggle btn btn-secondary">Filter Results</div> </div>  <div class="tabbed_content"> <div class="tab_content tab_1 tab_open"> <div class="search_results_block"> <div class="search_results_top"> <div class="search_header_text"><div class="et-search-content-commonname"><h1>STAT3: Products</h1><p>The STAT family of transcription factors, first described as key mediators of interferon signal transduction, are now recognized as signaling factors downstream of many cytokines, growth factors, and hormones. At least seven STATs exist: STAT1, 2, 3, 4, 5a, 5b, and 6.<span class="text_more collapsed"> They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. They are characterized structurally by the presence of the Src homology 2 (SH2) domain, and a C-terminal tyrosine phosphorylation site. Upon ligand binding, they are recruited to the activated receptor, via their SH2 domains, to receptor-associated tyrosine kinases of the Janus kinase family (JAK). Once phosphorylated by JAK, STATS are free to hetero- or homo-dimerize, and translocate to the nucleus where they bind DNA to regulate gene transcription.</span></p> <div class="cnsp-show-more-wrapper"><div class="cnsp-show-more collapsed">Show More</div></div> </div></div> <div class="search_header"> "<span class="search_term">STAT3</span>" has 42 results in Products. </div> <div class="search_type"> Sort by: <div class="select_wrapper"><select id="search_type_select">'; <option value="/target/stat3?sort=ranking,desc" selected="selected"> Best Match </option> <option value="/target/stat3?sort=product_title,asc"> Products (A-Z) </option> <option value="/target/stat3?sort=product_added,desc"> Newest </option> <option value="/target/stat3?sort=stars,desc"> Rating </option> </select></div>  </div>  </div>  <div class="cnsp-result search_result search_product"> <h2><a href="/products/proteome-profiler-human-phospho-kinase-array-kit_ary003c" class="ecommerce_link" data-id="ARY003C" data-variant="ARY003C" data-search_type="target_search" data-position="1" data-brand="rnd" data-name="Proteome Profiler Human Phospho-Kinase Array Kit" data-category="Proteome Profiler Antibody Arrays" data-sub_category="Proteome Profiler Antibody Array Kits" data-sub_category_id="135" data-price="841" data-currency_code="USD">Proteome Profiler Human Phospho-Kinase Array Kit</a> </h2> <div class="cnsp-description"> Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins </div> <div class="cnsp_content"> <div class="cnsp_table"> <div class="cnsp_table_row"> <div class="cnsp_meta"> <div class="cnsp_catnum"><a href="/products/proteome-profiler-human-phospho-kinase-array-kit_ary003c">ARY003C</a></div> <div class="cnsp_citations"><a href="/products/proteome-profiler-human-phospho-kinase-array-kit_ary003c#product-citations">389 Citations</a></div> <div class="cnsp_reviews"><a 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<a data-toggle="lightbox" data-gallery="ARY003C" data-title="Detection of Human Protein Kinase Phosphorylation in MCF-7 Cell Line." href="https://resources.rndsystems.com/images/datasheets/ary003c_proteome-profiler-human-phospho-kinase-array-kit-9112020141850.png"></a> </div> <div class="cnsp_buttons"> <div class="btn btn-septenary show_sizes_button collapsed">Show Size & Price</div> </div> </div> </div> <div class="cnsp_atc_wrapper"> <div class="add_to_cart_block collapsed" data-skus="ARY003C" data-skus_split="4" data-basesku="ARY003C" data-title="Proteome Profiler Human Phospho-Kinase Array Kit" style="display:none;"></div> </div> </div> </div> <div class="cnsp-result search_result search_product"> <h2><a href="/products/human-mouse-rat-stat3-antibody-232209_mab1799" class="ecommerce_link" data-id="MAB1799" data-variant="MAB1799,MAB1799-SP" data-search_type="target_search" data-position="2" data-brand="rnd" data-name="Human/Mouse/Rat STAT3 Antibody" data-category="Primary Antibodies" data-sub_category="Monoclonal Antibodies" data-sub_category_id="3" data-price="169" data-currency_code="USD">Human/Mouse/Rat STAT3 Antibody</a> </h2> <div class="cnsp-description"> </div> <div class="cnsp_content"> <div class="cnsp_table"> <div class="cnsp_table_row"> <div class="cnsp_meta"> <div class="cnsp_catnum"><a href="/products/human-mouse-rat-stat3-antibody-232209_mab1799">MAB1799</a></div> <div class="cnsp_citations"><a href="/products/human-mouse-rat-stat3-antibody-232209_mab1799#product-citations">22 Citations</a></div> <div class="cnsp_reviews"><a href="/products/human-mouse-rat-stat3-antibody-232209_mab1799#product-reviews"><span class="searchImage_star5"></span> 1 Review</a></div> <a data-toggle="lightbox" data-gallery="MAB1799" data-title="Detection of Human STAT3 by Western Blot." href="https://resources.rndsystems.com/images/datasheets/antibody/STAT3_MAB1799_Western_Blot_5993.jpg"><div class="cnsp_images">7 Images</div></a> <a data-toggle="lightbox" 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