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is-small is-grey tooltip is-tooltip-top" data-tooltip="Computer Vision and Pattern Recognition">cs.CV</span> <span class="tag is-small is-grey tooltip is-tooltip-top" data-tooltip="Machine Learning">cs.LG</span> </div> <div class="is-inline-block" style="margin-left: 0.5rem"> <div class="tags has-addons"> <span class="tag is-dark is-size-7">doi</span> <span class="tag is-light is-size-7"><a class="" href="https://doi.org/10.1007/978-3-031-72111-3_68">10.1007/978-3-031-72111-3_68 <i class="fa fa-external-link" aria-hidden="true"></i></a></span> </div> </div> </div> <p class="title is-5 mathjax"> Topologically Faithful Multi-class Segmentation in Medical Images </p> <p class="authors"> <span class="search-hit">Authors:</span> <a href="/search/eess?searchtype=author&amp;query=Berger%2C+A+H">Alexander H. Berger</a>, <a href="/search/eess?searchtype=author&amp;query=Stucki%2C+N">Nico Stucki</a>, <a href="/search/eess?searchtype=author&amp;query=Lux%2C+L">Laurin Lux</a>, <a href="/search/eess?searchtype=author&amp;query=Buergin%2C+V">Vincent Buergin</a>, <a href="/search/eess?searchtype=author&amp;query=Shit%2C+S">Suprosanna Shit</a>, <a href="/search/eess?searchtype=author&amp;query=Banaszak%2C+A">Anna Banaszak</a>, <a href="/search/eess?searchtype=author&amp;query=Rueckert%2C+D">Daniel Rueckert</a>, <a href="/search/eess?searchtype=author&amp;query=Bauer%2C+U">Ulrich Bauer</a>, <a href="/search/eess?searchtype=author&amp;query=Paetzold%2C+J+C">Johannes C. Paetzold</a> </p> <p class="abstract mathjax"> <span class="has-text-black-bis has-text-weight-semibold">Abstract</span>: <span class="abstract-short has-text-grey-dark mathjax" id="2403.11001v2-abstract-short" style="display: inline;"> Topological accuracy in medical image segmentation is a highly important property for downstream applications such as network analysis and flow modeling in vessels or cell counting. Recently, significant methodological advancements have brought well-founded concepts from algebraic topology to binary segmentation. However, these approaches have been underexplored in multi-class segmentation scenari&hellip; <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('2403.11001v2-abstract-full').style.display = 'inline'; document.getElementById('2403.11001v2-abstract-short').style.display = 'none';">&#9661; More</a> </span> <span class="abstract-full has-text-grey-dark mathjax" id="2403.11001v2-abstract-full" style="display: none;"> Topological accuracy in medical image segmentation is a highly important property for downstream applications such as network analysis and flow modeling in vessels or cell counting. Recently, significant methodological advancements have brought well-founded concepts from algebraic topology to binary segmentation. However, these approaches have been underexplored in multi-class segmentation scenarios, where topological errors are common. We propose a general loss function for topologically faithful multi-class segmentation extending the recent Betti matching concept, which is based on induced matchings of persistence barcodes. We project the N-class segmentation problem to N single-class segmentation tasks, which allows us to use 1-parameter persistent homology, making training of neural networks computationally feasible. We validate our method on a comprehensive set of four medical datasets with highly variant topological characteristics. Our loss formulation significantly enhances topological correctness in cardiac, cell, artery-vein, and Circle of Willis segmentation. <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('2403.11001v2-abstract-full').style.display = 'none'; document.getElementById('2403.11001v2-abstract-short').style.display = 'inline';">&#9651; Less</a> </span> </p> <p class="is-size-7"><span class="has-text-black-bis has-text-weight-semibold">Submitted</span> 9 October, 2024; <span class="has-text-black-bis has-text-weight-semibold">v1</span> submitted 16 March, 2024; <span class="has-text-black-bis has-text-weight-semibold">originally announced</span> March 2024. </p> <p class="comments is-size-7"> <span class="has-text-black-bis has-text-weight-semibold">Journal ref:</span> MICCAI 2024, Lecture Notes in Computer Science, vol. 15008, pp. 721-731, 2024 </p> </li> </ol> <div class="is-hidden-tablet"> <!-- feedback for mobile only --> <span class="help" style="display: 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