间氟苯乙酮的化学性质与稳定性研究

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class="zy_top zy-top_bottom"> <div class="zhiyao_nav_all contain"> <div class="visibleBox"> <div class="cont_l"> <div class="c_l_top"> <i class="iconfont icon-caidan"></i> 产品分类导航 </div> <div class="c_l_list"> <ul> <li> <span> <a href="/Products/list-htm-catid-4.html"> 原料药</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-4.html" target="_blank">原料药</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-5.html"> 维生素类</a> <a href="/Products/list-htm-catid-6.html"> 四环素类</a> <a href="/Products/list-htm-catid-7.html"> 青霉素类</a> <a href="/Products/list-htm-catid-8.html"> 头孢菌素类</a> <a href="/Products/list-htm-catid-9.html"> 激素类</a> <a href="/Products/list-htm-catid-10.html"> 氨基酸及其衍生物</a> <a href="/Products/list-htm-catid-11.html"> 氨基糖苷类</a> <a href="/Products/list-htm-catid-12.html"> 大环内酯类</a> <a href="/Products/list-htm-catid-13.html"> 磺胺类</a> <a href="/Products/list-htm-catid-14.html"> 氯霉素类</a> <a 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href="/Products/list-htm-catid-86.html"> 消化系统制剂</a> <a href="/Products/list-htm-catid-87.html"> 呼吸系统制剂</a> <a href="/Products/list-htm-catid-88.html"> 循环系统制剂</a> <a href="/Products/list-htm-catid-89.html"> 神经系统类制剂</a> <a href="/Products/list-htm-catid-90.html"> 血液系统药制剂</a> <a href="/Products/list-htm-catid-91.html"> 泌尿与生殖系统制剂</a> <a href="/Products/list-htm-catid-93.html"> 调节免疫功能制剂</a> <a href="/Products/list-htm-catid-94.html"> 调节水、电解质及酸碱平衡制剂</a> <a href="/Products/list-htm-catid-95.html"> 维生素、矿物质与氨基酸类制剂</a> <a href="/Products/list-htm-catid-96.html"> 酶类及其它生化制剂</a> <a href="/Products/list-htm-catid-97.html"> 解热镇痛类制剂</a> <a href="/Products/list-htm-catid-98.html"> 滋补营养药</a> <a href="/Products/list-htm-catid-99.html"> 有关激素类药</a> <a href="/Products/list-htm-catid-100.html"> 内分泌及代谢类制剂</a> <a href="/Products/list-htm-catid-101.html"> 清热解毒制剂</a> <a href="/Products/list-htm-catid-102.html"> 心脑血管类制剂</a> <a href="/Products/list-htm-catid-103.html"> 其它药品制剂</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> <a href="/Products/list-htm-catid-104.html"> 药用辅料</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-104.html" target="_blank">药用辅料</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-105.html"> 赋形剂</a> <a href="/Products/list-htm-catid-106.html"> 崩解剂</a> <a href="/Products/list-htm-catid-107.html"> 润滑剂</a> <a href="/Products/list-htm-catid-108.html"> 助流剂</a> <a href="/Products/list-htm-catid-109.html"> 包衣材料</a> <a href="/Products/list-htm-catid-110.html"> 增塑剂</a> <a href="/Products/list-htm-catid-111.html"> 肠溶材料</a> <a href="/Products/list-htm-catid-112.html"> 表面活性剂</a> <a href="/Products/list-htm-catid-113.html"> 溶媒</a> <a href="/Products/list-htm-catid-114.html"> 抗氧剂</a> <a href="/Products/list-htm-catid-115.html"> 遮光剂</a> <a href="/Products/list-htm-catid-116.html"> 矫味剂</a> <a href="/Products/list-htm-catid-117.html"> 甜味剂</a> <a href="/Products/list-htm-catid-118.html"> 香精</a> <a href="/Products/list-htm-catid-119.html"> 着色剂</a> <a href="/Products/list-htm-catid-120.html"> 促透剂</a> <a href="/Products/list-htm-catid-121.html"> 助滤剂</a> <a href="/Products/list-htm-catid-122.html"> 澄清剂</a> <a href="/Products/list-htm-catid-123.html"> 防腐剂</a> <a href="/Products/list-htm-catid-124.html"> 稳定剂</a> <a href="/Products/list-htm-catid-125.html"> ＰＨ调节剂</a> <a href="/Products/list-htm-catid-126.html"> 催化剂</a> <a href="/Products/list-htm-catid-127.html"> 其他药用辅料</a> </div> <div class="list_list_img"> </div> </div> </li> <li> <span> <a href="/Products/list-htm-catid-128.html"> 合同外包、定制服务及咨询</a> </span> <div class="list_list"> <div class="title"> <a href="/Products/list-htm-catid-128.html" target="_blank">合同外包、定制服务及咨询</a> </div> <div class="list_list_item"> <a href="/Products/list-htm-catid-129.html"> 合同研发外包</a> <a href="/Products/list-htm-catid-130.html"> 合同生产外包</a> <a href="/Products/list-htm-catid-131.html"> 咨询与服务</a> </div> <div class="list_list_img"> </div> </div> </li> <li> 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<div></div> </a> <a href="/Products/" class=""> 产品 <div></div> </a> <a href="/suppliers/" class=""> 供应商 <div></div> </a> <a href="/buy/" class=""> 采购通 <div></div> </a> <a href="/news/" class="active"> 资讯 <div></div> </a> <a href="/meeting/" class=""> 会展活动 <div></div> </a> <a class="exhibiton_menu" onmousemove="showEx()" onmouseleave="closeEx()" href="javascript:void(0)">CPHI & PMEC China展 <div></div> </a> </div> <div class="exhibition" onmouseleave="closeEx()" onmouseenter="showEx()" style="height: max-content;"> <p><a href="https://www.cphi-china.cn/" target="_blank">CPHI China</a></p> <p><a href="https://www.pmecchina.com/" target="_blank">PMEC China</a></p> <p><a href="https://www.cphi-china.cn/shenzhen/" target="_blank">CPHI & PMEC 深圳展</a></p> </div> </div> </div> <div class="newList_route"> <div class="content"> <a href="/">CPHI制药在线</a> <label>></label> <a href="/news/">资讯</a> <label>></label> <a href="javascript:;">间氟苯乙酮的化学性质与稳定性研究</a> <label>></label> </div> </div> <div class="newsDetail"> <div class="content flex_between"> <input id="newsId" type="hidden" value="279703"/> <div class="newsDetail_article"> <div class="zixun-contain"> <h1 class="newsDetail_article_title">间氟苯乙酮的化学性质与稳定性研究</h1> <div class="newsDetail_article_create flex_between"> <div class="exam_news_createlocal"> 热门推荐： <a href="/news/search-htm-txtSearch-间氟苯乙酮-hide_search-4.html">间氟苯乙酮</a> <label>,</label> <a href="/news/search-htm-txtSearch-化学性质-hide_search-4.html">化学性质</a> <label>,</label> <a href="/news/search-htm-txtSearch-含氟有机化合物-hide_search-4.html">含氟有机化合物</a> <label>,</label> </div> <div class="exam_news_createtime" style="display: flex"> <div> 来源：CPHI制药在线</div> &emsp; 2024-11-22</div> </div> <div class="news-brief"> 间氟苯乙酮（m-Fluoroacetophenone），化学式为C8H7FO，是一种重要的含氟有机化合物，在制药领域中作为合成药物的中间体具有重要应用。 </div> <div class="newsDetail_article_content"> <p><img style="display: block; margin-left: auto; margin-right: auto;" src="https://cimg.cphi.cn/img_Cphi_cn/image/2024/11/22/17_55_43.png" alt="间氟苯乙酮" width="300" height="295" /></p> <p>       <strong><a href="https://www.cphi.cn/Products/show-48947.html" target="_blank" rel="noopener">间氟苯乙酮</a></strong>（m-Fluoroacetophenone），化学式为C8H7FO，是一种重要的含氟有机化合物，在制药领域中作为合成药物的中间体具有重要应用。它具有酮的通性，由于分子中含有一个潜在的旋光性碳原子和一个强吸电子的氟原子，因此它在化学反应中表现出一些特殊的性质。</p> <p>       在化学性质方面，间氟苯乙酮是一种无色透明液体，具有特殊的芳香气味。它的密度为1.103g/cm3，沸点为204°C at 760 mmHg，闪点为70.4°C，蒸气压为0.27mmHg at 25°C。稳定性方面，间氟苯乙酮在常温常压下相对稳定，但应避免与强氧化剂、强酸、强碱等物质接触，以防发生危险反应。</p> <p>       在制药领域的应用中，间氟苯乙酮主要用于合成一些特定的药物分子，如抗炎药、抗菌药等。由于其含有氟原子，可以提高药物的生物活性和药代动力学特性。此外，含氟化合物通常具有更好的脂溶性，这有助于药物在体内的吸收和分布。</p> <p>       在制备工艺方面，间氟苯乙酮通常通过间溴氟苯与镁反应生成格氏试剂，然后经过乙酰化、水解等步骤制得。在合成过程中，对原料配比、溶剂用量、反应时间及温度等条件进行了优化，以提高产率和纯度。制备格氏试剂时，加入少许碘可以缩短反应诱导期，而控制溴氟苯的滴加时间和总反应时间对于产物的收率和质量至关重要。</p> <p>       储存条件对间氟苯乙酮的稳定性至关重要。它应在密封、干燥、阴凉的环境中保存，避免光照和高温。此外，由于其易燃性质，应远离火源和热源。在工业生产中，应采取适当的安全措施，如使用防爆设备、通风系统和防护服。</p> <p>       总之，<strong><a href="https://www.cphi.cn/Products/show-48947.html" target="_blank" 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