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Guidelines for Manuscript Type and Related Ethics and Relevant Documents </div> <div class="bpgnews"> <div class="newsstat"> <span>Browse:&nbsp;</span><span>211024</span>&nbsp;&nbsp;|&nbsp;&nbsp; <span>Download:&nbsp;</span><span>2914</span>&nbsp;&nbsp;|&nbsp;&nbsp; <span>Issue Date:&nbsp;</span><span>2017-06-27</span> </div> <div class="htmlcontent"> <p style="line-height:150%"><a name="OLE_LINK3"><span style="font-size:12.0pt;line-height:150%; font-family:'Book Antiqua','serif';color:black;">Last updated December 17, 2021</span></a></p> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:blue">&nbsp;</span></strong></p> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Guidelines for Manuscript Type and Related Ethics and Relevant Documents</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">&nbsp;</span></p> <p style="line-height:150%; text-autospace:none"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">First, for all manuscripts involving human studies and/or animal experiments, author(s) must submit the related formal ethics documents that were reviewed and approved by their local ethical review committee. This is mandatory and is one of the determining factors for whether or not the manuscript will be sent for peer review or finally accepted. If human and animal studies received waiver of the approval requirement from the ethics committee, the author(s) must provide an official statement to this effect made by the ethics committee. The guidelines for manuscript type and related ethics and relevant documents/statements are as follows:</span></p> <p style="line-height:150%; text-autospace:none"><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">1</span></strong> <strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Ethics and relevant document(s) required for the different manuscript types</span></strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;"> </span></p> <table style="margin-left:5.4pt;border-collapse:collapse; border:none;" width="642" cellspacing="0" cellpadding="0" border="1"> <tbody><tr> <td style="width:111.35pt;border:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="148" valign="top"> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;Times New Roman';color:black;">Manuscript type</span></strong></p> </td> <td style="width:301.5pt;border:solid windowtext 1.0pt; border-left:none;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma; color:black;">Name(s) of ethics and relevant documents required</span></strong></p> </td> <td style="width:68.65pt;border:solid windowtext 1.0pt; border-left:none;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Sample</span></strong></p> </td> </tr> <tr> <td rowspan="2" style="width:111.35pt;border:solid windowtext 1.0pt; border-top:none; padding:0cm 5.4pt 0cm 5.4pt" width="148" valign="top"> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Editorial, Review, Frontier, Field of Vision, Minireview, Guidelines, Opinion Review, Letter to the Editor, Correction, Retraction Note&nbsp;</span></strong></p> </td> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">(1 of 2)<strong> Conflict-of-Interest Disclosure Form</strong></span> </p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please download the fillable ICMJE Form for Disclosure of Potential Conflicts of Interest (PDF), fill it in, and then upload the completed PDF version to the system.</span></p> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Note:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;"> The Corresponding Author is responsible for filling out a Conflict-of-Interest Disclosure Form.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Conflict-of-interest_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">(2 of 2) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Copyright License Agreement</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Please upload the PDF version of the Copyright License Agreement Form that has been signed by all authors.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/BPG_Copyright_License_Agreement.docx"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td rowspan="6" style="width:111.35pt;border:solid windowtext 1.0pt; border-top:none; padding:0cm 5.4pt 0cm 5.4pt" width="148" valign="top"> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Basic study</span></strong></p> </td> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(1 of 6) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Institutional Review Board Approval Form or Document</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please upload the primary version (PDF) of the Institutional Review Board’s official approval, prepared in the official language of the authors’ country to the system; for example, authors from China should upload the Chinese version of the document, authors from Italy should upload the Italian version of the document, authors from Germany should upload the Deutsch version of the document, and authors from the United States and the United Kingdom should upload the English version of the document, <em>etc</em>.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Institutional_review_board_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(2 of 6) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Institutional Animal Care and Use Committee Approval Form or Document</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please upload the primary version (PDF) of the Institutional Animal Care and Use Committee’s official approval in the official language of the authors’ country to the system; for example, authors from China should upload the Chinese version of the document, authors from Italy should upload the Italian version of the document, authors from Germany should upload the Deutsch version of the document, and authors from the United States and the United Kingdom should upload the English version of the document, <em>etc</em>.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Institutional_animal_care_and_use_committee_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr style="height:19.75pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:19.75pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(3 of 6) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Conflict-of-Interest Disclosure Form</span></strong> </p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please download the fillable ICMJE Form for Disclosure of Potential Conflicts of Interest (PDF), fill it in, and then upload the completed PDF version to the system.</span></p> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Note:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;"> The Corresponding Author is responsible for filling out a Conflict-of-Interest Disclosure Form.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:19.75pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Conflict-of-interest_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr style="height:69.25pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:69.25pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(4 of 6) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Copyright License Agreement</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Please upload the PDF version of the Copyright License Agreement Form that has been signed by all authors.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:69.25pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/BPG_Copyright_License_Agreement.docx"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr style="height:28.3pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:28.3pt" width="402" valign="top"><p style="margin-left:-1.0pt; text-indent:-.05pt;line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">(5 of 6) <strong>The ARRIVE Guidelines</strong><br />In order to improve the quality of Basic Study manuscripts, authors should: </span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">1) Download ‘The ARRIVE Guidelines’ before the peer review process;</span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">2) Complete the</span> <span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">ARRIVE checklist to ensure that the manuscript meets the requirements of the ARRIVE Guidelines;</span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">3) State on the title page of the manuscript that the ARRIVE Guidelines have been adopted; </span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">4) And, </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;background:white">upload the PDF version of the completed </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">ARRIVE checklist</span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;background:white"> to the system.</span> </p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:28.3pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/The_ARRIVE_Guidelines_English.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download(English)</span></a></p> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/The_ARRIVE_Guidelines_Chinese.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download(Chinese)</span></a></p> </td> </tr> <tr style="height:19.5pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:19.5pt" width="402" valign="top"> <p style="line-height:150%; background:white"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">(6 of 6)&nbsp;<strong>Biostatistics Review Certificate</strong></span></p> <p style="line-height:150%; background:white"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">Please upload to the system the PDF version of a statement affirming that the statistical review of the study was performed by a biomedical statistician.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:19.5pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Biostatistics_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td rowspan="5" style="width:111.35pt;border:solid windowtext 1.0pt; border-top:none; padding:0cm 5.4pt 0cm 5.4pt" width="148" valign="top"> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Retrospective study, Clinical Practice study</span></strong></p> </td> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(1 of 5) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Institutional Review Board Approval Form or Document</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please upload the primary version (PDF) of the Institutional Review Board’s official approval in the official language of the authors’ country to the system; for example, authors from China should upload the Chinese version of the document, authors from Italy should upload the Italian version of the document, authors from Germany should upload the Deutsch version of the document, and authors from the United States and the United Kingdom should upload the English version of the document, <em>etc</em>.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Institutional_review_board_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(2 of 5) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Signed Informed Consent Form(s) or Document(s)</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please upload the primary version (PDF) of the Informed Consent Form </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">that has been </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma; color:black;">signed by all subjects and investigators of the study, prepared in the official language of the authors’ country to the system; for example, authors from China should upload the Chinese version of the document, authors from Italy should upload the Italian version of the document, authors from Germany should upload the Deutsch version of the document, and authors from the United States and the United Kingdom should upload the English version of the document, <em>etc</em>.</span></p><p style="line-height:150%"><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma; color:black;"><strong>Note: </strong>To obey the publication ethics and improve the protection of all patients' rights to privacy, the authors should provide the informed consent form on which the patient's name, address, birthday, address, ward, bed number, hospital number and other private information are obfuscated.<br /></span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Informed_consent_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(3 of 5) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Conflict-of-Interest Disclosure Form</span></strong> </p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please download the fillable ICMJE Form for Disclosure of Potential Conflicts of Interest (PDF), fill it in, and then upload the completed PDF version to the system.</span></p> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Note:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;"> The Corresponding Author is responsible for filling out a Conflict-of-Interest Disclosure Form.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Conflict-of-interest_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr style="height:60.25pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:60.25pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(4 of 5) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Copyright License Agreement</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Please upload the PDF version of the Copyright License Agreement Form that has been signed by all authors.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:60.25pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/BPG_Copyright_License_Agreement.docx"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'">&nbsp;</span></p> </td> </tr> <tr style="height:90.85pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:90.85pt" width="402" valign="top"> <p style="line-height:150%; background:white"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">(5 of 5)&nbsp;<strong>Biostatistics Review Certificate</strong></span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">Please upload the PDF version of a statement affirming that the statistical review of the study was performed by a biomedical statistician to the system.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:90.85pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Biostatistics_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%; font-family:'Book Antiqua','serif'"><span style="text-decoration:none">&nbsp;</span></span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%; font-family:'Book Antiqua','serif'"><span style="text-decoration:none">&nbsp;</span></span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'">&nbsp;</span></p> </td> </tr> <tr> <td rowspan="6" style="width:111.35pt;border:solid windowtext 1.0pt; border-top:none; padding:0cm 5.4pt 0cm 5.4pt" width="148" valign="top"> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Case Control study, Observational study, Retrospective Cohort study</span></strong></p> </td> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(1 of 6) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Institutional Review Board Approval Form or Document</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please upload the primary version (PDF) of the Institutional Review Board’s official approval in the official language of the authors’ country to the system; for example, authors from China should upload the Chinese version of the document, authors from Italy should upload the Italian version of the document, authors from Germany should upload the Deutsch version of the document, and authors from the United States and the United Kingdom should upload the English version of the document, <em>etc</em>.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Institutional_review_board_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(2 of 6) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Signed Informed Consent Form(s) or Document(s)</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please upload the primary version (PDF) of the Informed Consent Form </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">that has been </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma; color:black;">signed by all subjects and investigators of the study, prepared in the official language of the authors’ country to the system; for example, authors from China should upload the Chinese version of the document, authors from Italy should upload the Italian version of the document, authors from Germany should upload the Deutsch version of the document, and authors from the United States and the United Kingdom should upload the English version of the document, <em>etc</em>.</span></p><p style="line-height:150%"><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma; color:black;"><strong>Note: </strong>To obey the publication ethics and improve the protection of all patients' rights to privacy, the authors should provide the informed consent form on which the patient's name, address, birthday, address, ward, bed number, hospital number and other private information are obfuscated.<br /></span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Informed_consent_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr style="height:15.25pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.25pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(3 of 6) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Conflict-of-Interest Disclosure Form</span></strong> </p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please download the fillable ICMJE Form for Disclosure of Potential Conflicts of Interest (PDF), fill it in, and then upload the completed PDF version to the system.</span></p> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Note:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;"> The Corresponding Author is responsible for filling out a Conflict-of-Interest Disclosure Form.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:15.25pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Conflict-of-interest_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr style="height:69.25pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:69.25pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(4 of 6) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Copyright License Agreement</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Please upload the PDF version of the Copyright License Agreement Form that has been signed by all authors.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:69.25pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/BPG_Copyright_License_Agreement.docx"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%; font-family:'Book Antiqua','serif'"><span style="text-decoration:none">&nbsp;</span></span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'">&nbsp;</span></p> </td> </tr> <tr style="height:27.0pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:27.0pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(5 of 6) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">STROBE Statement</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">In order to improve the quality of Case Control study, Observational study and Retrospective Cohort study manuscripts, authors should: </span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">1) Download the ‘</span><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">STROBE Statement—checklist of items that should be included in reports of observational studies’</span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;"> before the peer review process; </span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">2) Complete the</span> <span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">checklist to ensure that the manuscript meets the requirements of the </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">STROBE Statement</span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">; </span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">3) State on the title page of the manuscript that the guidelines of the STROBE Statement have been adopted; </span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">4) And, </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;background:white">upload the PDF version of the completed </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">checklist</span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;background:white"> to the system.</span> </p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:27.0pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/STROBE.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr style="height:22.5pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt" width="402" valign="top"> <p style="line-height:150%; background:white"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">(6 of 6)&nbsp;<strong>Biostatistics Review Certificate</strong></span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">Please upload the PDF version of a statement affirming that the statistical review of the study was performed by a biomedical statistician to the system.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:22.5pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Biostatistics_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td rowspan="7" style="width:111.35pt;border:solid windowtext 1.0pt; border-top:none; padding:0cm 5.4pt 0cm 5.4pt" width="148" valign="top"> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Clinical Trials study, Prospective study, Randomized Controlled trial, Randomized Clinical trial</span></strong></p> </td> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(1 of 7) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Institutional Review Board Approval Form or Document</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please upload the primary version (PDF) of the Institutional Review Board’s official approval in official language of the authors’ country to the system; for example, authors from China should upload the Chinese version of the document, authors from Italy should upload the Italian version of the document, authors from Germany should upload the Deutsch version of the document, and authors from the United States and the United Kingdom should upload the English version of the document, <em>etc</em>.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Institutional_review_board_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(2 of 7) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Clinical Trial Registration Statement</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please upload the PDF version of</span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;"> the document providing the registration identification number and the URL for the trial's registry</span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma; color:black;">.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Clinical_trial_registration_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(3 of 7)</span> <strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Signed Informed Consent Form(s) or Document(s)</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please upload the primary version (PDF) of the Informed Consent Form </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">that has been </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma; color:black;">signed by all subjects and investigators of the study, prepared in the official language of the authors’ country to the system; for example, authors from China should upload the Chinese version of the document, authors from Italy should upload the Italian version of the document, authors from Germany should upload the Deutsch version of the document, and authors from the United States and the United Kingdom should upload the English version of the document, <em>etc</em>.</span></p><p style="line-height:150%"><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma; color:black;"><strong>Note:</strong> To obey the publication ethics and improve the protection of all patients' rights to privacy, the authors should provide the informed consent form on which the patient's name, address, birthday, address, ward, bed number, hospital number and other private information are obfuscated.<br /></span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Informed_consent_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(4 of 7) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Conflict-of-Interest Disclosure Form</span></strong> </p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please download the fillable ICMJE Form for Disclosure of Potential Conflicts of Interest (PDF), fill it in, and then upload the completed PDF version to the system.</span></p> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Note:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;"> The Corresponding Author is responsible for filling out a Conflict-of-Interest Disclosure Form.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Conflict-of-interest_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr style="height:61.6pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:61.6pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(5 of 7) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Copyright License Agreement</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Please upload the PDF version of the Copyright License Agreement Form that has been signed by all authors.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:61.6pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/BPG_Copyright_License_Agreement.docx"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'">&nbsp;</span></p> </td> </tr> <tr style="height:76.65pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:76.65pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(6 of 7) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">CONSORT 2010 Statement</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">In order to improve the quality of Clinical Trials study, Prospective study, Randomized Controlled trial and Randomized Clinical trial manuscripts, authors should:</span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">1) Download the ‘CONSORT 2010 checklist of information to include when reporting a randomised trial</span><span style="font-size:12.0pt;line-height:150%; font-family:'Book Antiqua','serif';color:black;">’</span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;"> before the peer review process;</span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">2) Complete the</span> <span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">checklist to ensure that the manuscript meets the requirements of the CONSORT 2010 </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Statement</span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">;</span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">3) State on the title page of the manuscript that the guidelines of the CONSORT 2010 Statement have been adopted; </span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">4) And, </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;background:white">upload the PDF version of the completed </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">checklist</span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;background:white"> to the system.</span> </p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:76.65pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/CONSORT_2010_Checklist.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr style="height:27.3pt"> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:27.3pt" width="402" valign="top"> <p style="line-height:150%; background:white"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">(7 of 7)&nbsp;<strong>Biostatistics Review Certificate</strong></span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">Please upload the PDF version of a statement affirming that the statistical review of the study was performed by a biomedical statistician to the system.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt;height:27.3pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Biostatistics_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td rowspan="4" style="width:111.35pt;border:solid windowtext 1.0pt; border-top:none; padding:0cm 5.4pt 0cm 5.4pt" width="148" valign="top"> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Evidence-Based Medicine, Scientometrics, Systematic review, Meta-Analysis</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">&nbsp;</span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">&nbsp;</span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">&nbsp;</span></p> </td> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(1 of 4) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Conflict-of-Interest Disclosure Form</span></strong> </p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please download the fillable ICMJE Form for Disclosure of Potential Conflicts of Interest (PDF), fill it in, and then upload the completed PDF version to the system.</span></p> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Note:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;"> The Corresponding Author is responsible for filling out a Conflict-of-Interest Disclosure Form.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Conflict-of-interest_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(2 of 4) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Copyright License Agreement</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Please upload the PDF version of the Copyright License Agreement Form that has been signed by all authors.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/BPG_Copyright_License_Agreement.docx"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(3 of 4) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">PRISMA 2009 Checklist</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">In order to improve the quality of </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Systematic review and Meta-Analysis manuscripts</span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">, authors should:</span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">1) Download the ‘PRISMA 2009 Checklist</span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">’</span><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;"> before the peer review process; </span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">2) Complete the</span> <span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">checklist to ensure that the manuscript meets the requirements of the PRISMA 2009 </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Statement</span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">; </span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">3) State on the title page of the manuscript that the guidelines of the PRISMA 2009 Statement have been adopted; </span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">4) And, </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;background:white">upload the PDF version of the completed </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;color:black;">checklist</span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;background:white"> to the system.</span> </p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/PRISMA_2009_Checklist.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%; background:white"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">(4 of 4)&nbsp;<strong>Biostatistics Review Certificate</strong></span></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">Please upload the PDF version of a statement affirming that the statistical review of the study was performed by a biomedical statistician to the system.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Biostatistics_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td rowspan="4" style="width:111.35pt;border:solid windowtext 1.0pt; border-top:none; padding:0cm 5.4pt 0cm 5.4pt" width="148" valign="top"> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Case report</span></strong></p> </td> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(1 of 4) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Signed Consent for Treatment Form(s) or Document(s)<br /></span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please upload the primary version (PDF) of the Consent for Treatment Form(s) or Document(s) </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">that has been </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma; color:black;">signed by the patients in the study, prepared in the official language of the authors’ country to the system; for example, authors from China should upload the Chinese version of the document, authors from Italy should upload the Italian version of the document, authors from Germany should upload the Deutsch version of the document, and authors from the United States and the United Kingdom should upload the English version of the document, <em>etc</em>.</span></p><p style="line-height:150%"><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Tahoma; color:black;"><strong>Note: </strong>To obey the publication ethics and improve the protection of all patients' rights to privacy, the authors should provide the informed consent form on which the patient's name, address, birthday, address, ward, bed number, hospital number and other private information are obfuscated.<br /></span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Informed_consent_statement-Case_report.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(2 of 4) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;color:black;">Conflict-of-Interest Disclosure Form</span></strong> </p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">Please download the fillable ICMJE Form for Disclosure of Potential Conflicts of Interest (PDF), fill it in, and then upload the completed PDF version to the system.</span></p> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;">Note:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';color:black;"> The Corresponding Author is responsible for filling out a Conflict-of-Interest Disclosure Form.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/Conflict-of-interest_statement.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Tahoma;color:black;">(3 of 4) </span><strong><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Copyright License Agreement</span></strong></p> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">Please upload the PDF version of the Copyright License Agreement Form that has been signed by all authors.</span></p> </td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/BPG_Copyright_License_Agreement.docx"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> <tr> <td style="width:301.5pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="402" valign="top"><span style="font-size: 14pt;"></span><p style="text-align:justify;text-justify:inter-ideograph; line-height:150%;"><span style="font-size: 14pt;"><span style="font-size: 12pt;"><span style="font-family: 'Book Antiqua','serif',Arial;color:black;">(4 of 4)<strong> CARE Checklist – 2016: Information for writing a case report&nbsp;</strong><br /><br />In order to improve the quality of Case report manuscripts, authors should:<br /><br />1) Download the ‘CARE Checklist – 2016: Information for writing a case report’ before the peer review process;<br /><br />2) Complete the checklist to ensure that the manuscript meets the requirements of the CARE Checklist – 2016: Information for writing a case report;<br /><br />3) State on the title page of the manuscript that the guidelines of the “CARE Checklist – 2016: Information for writing a case report” have been adopted; <br /></span></span></span></p><p style="text-align:justify;text-justify:inter-ideograph; line-height:150%;"><span style="font-size: 14pt;"><span style="font-size: 12pt;"><span style="font-family: 'Book Antiqua','serif',Arial;color:black;">4) And, </span><span style="font-family:'Book Antiqua','serif'; color:black;background:white">upload the PDF version of the completed </span><span style="font-family: 'Book Antiqua','serif',Arial;color:black;">checklist</span></span><span style="font-family:'Book Antiqua','serif'; color:black;background:white"><span style="font-size: 12pt;"> to the system</span>.</span> </span></p><span style="font-size: 14pt;"> </span></td> <td style="width:68.65pt;border-top:none;border-left: none;border-bottom:solid windowtext 1.0pt;border-right:solid windowtext 1.0pt;padding:0cm 5.4pt 0cm 5.4pt" width="92" valign="top"> <p style="line-height:150%"><a href="https://f6publishing.blob.core.windows.net/customuploadedfiles/CAREchecklist-Eng-20160131.pdf"><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif'">Download</span></a></p> </td> </tr> </tbody></table> <p style="line-height:150%"><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif'; color:black;">&nbsp;</span></p> <p style="line-height:150%"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;;">2 ETHICS POLICIES/STATEMENTS</span></strong></p> <p style="line-height:150%"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;;">2.</span></strong><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond-Bold;">1 </span></strong><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">Institutional review board.</span></strong> <span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',宋体;Times New Roman';color:black">Any article describing a study (basic research, clinical research, and case report) </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;">involving human and/or animal subjects is required to have the institutional review board (IRB) name, whether institutional (part of the author(s)’ academic/medical institution, such as the Oak Grove Children’s Hospital Institutional Review Board) or commercial/independent/private (contracted for-profit organizations, such as the </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;Times New Roman';color:black;">ClinicCare Coalition for Human Rights Institutional Review Board</span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;">), stated explicitly on the title page. </span></p> <p style="line-height:150%;"><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;">Sample wording:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;"> The study was reviewed and approved by the [Name of Institution or Organization] Institutional Review Board.</span> </p> <p style="line-height:150%;"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond-Bold;">2.2 </span></strong><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">Institutional animal care and use committee.</span></strong> <span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',宋体;Times New Roman';color:black">Any article describing a study (basic research) </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;">involving animal subjects is required to have the institutional animal care and use committee (IACUC)’s institution name (such as the Genovese Institute) and protocol number (such as 14-9347-39G or EN-21549) stated explicitly in the </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black">title page section.</span> </p> <p style="line-height:150%;"><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;">Sample wording:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;"> All procedures involving animals were reviewed and approved by the Institutional Animal Care and Use Committee of the [Name of Institution] (IACUC protocol number: [protocol number]). </span></p> <p style="line-height:150%;"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond-Bold;">2.3 </span></strong><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">Animal care and use statement<em>.</em></span></strong> <span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black">Any manuscript describing a study </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',宋体;Times New Roman';color:black">(basic research) </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black">that used animal subjects must include a statement in the Materials and Methods section affirming that all appropriate measures were taken to minimize pain or discomfort, and details of the animals’ care should be provided.</span> </p> <p style="line-height:150%;"><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;">Example wording:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;"> The animal protocol was designed to minimize pain or discomfort to the animals. The animals were acclimatized to laboratory conditions (23 °C, 12 h/12 h light/dark, 50% humidity, <em>ad libitum</em> access to food and water) for 2 wk prior to experimentation. Intragastric gavage administration was carried out with conscious animals, using straight gavage needles appropriate for the animal size (15-17 g body weight: 22 gauge, 1 inch length, 1.25 mm ball diameter). All animals were euthanized by </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;Times New Roman';color:black;">barbiturate overdose (intravenous injection, 150 mg/kg pentobarbital sodium) for tissue collection.</span></p> <p style="line-height:150%;"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">2.4 </span></strong><strong><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">Clinical trial registration</span></strong><strong><span style="font-size:12.0pt;line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">.</span></strong> <span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;Times New Roman';color:black;">Any research study (clinical trial) that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes must be registered. Authors have 6 mo from the first patient enrollment to register the trial, but BPG recommends registration prior to enrollment. This registration policy applies to prospective, randomized, controlled trials only. Authors must provide the registration identification number and the URL for the trial's registry. </span></p> <p style="line-height:150%;"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;;">Sample wording:</span></strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;;"> This study is registered at [URL]. The registration identification number is [registration identification number].</span></p> <p style="line-height:150%;"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond-Bold;">2.5</span></strong> <strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">Informed consent<em>.</em></span></strong> <span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Arial;Times New Roman';color:black;">A</span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',宋体;Times New Roman';color:black;">ny research article describing a study (clinical research and case report) involving humans should contain a statement in the </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;">title page</span><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;Times New Roman';color:black;"> clearly stating that all involved persons (subjects or legally authorized representative) gave their informed consent </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black;">(written or verbal, as appropriate) </span><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',宋体;Times New Roman';color:black;">prior to study inclusion. In general, the BPG requires that any and all details that might disclose the identity of the subjects under study should be omitted or anonymized. In the rare situation that a study participant’s identifiable information is crucial to the case presentation, the statement of informed consent is absolutely necessary, unless the participant is deceased. </span></p> <p style="line-height:150%;"><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Garamond;Times New Roman';color:black;">Sample wording:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Garamond;Times New Roman';color:black;"> All study participants, or their legal guardian, provided informed written consent prior to study enrollment.</span></p> <p style="line-height:150%;"><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',宋体;Times New Roman';color:black;">Note:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',宋体;Times New Roman';color:black;"> Waiver of informed consent for human study subjects may be justifiable under certain rare and specific conditions, such as for a trial with demonstrated minimal risk or cases of emergency care. Authors may petition the BPG for waiver of informed consent, but there is no guarantee that the petition will be granted. In general, the BPG favors the requirement of informed consent for all reports of information (anonymized or identifiable) and reserves the right to refuse publication of such if informed consent was not obtained.</span></p> <p style="line-height:150%;"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond-Bold;">2.6 </span></strong><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;">Conflict-of-interest<em>.</em></span></strong> <span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black">A conflict-of-interest statement is required for all article and study types. In the interests of transparency and helping reviewers to assess any potential bias in a study’s design, interpretation of its results or presentation of its scientific/medical content, the BPG requires all authors of each paper to declare in the title page any conflicting interests (including but not limited to commercial, personal, political, intellectual or religious interests) that are related to the work submitted for consideration of publication. </span></p> <p style="line-height:150%;"><strong><span style="font-size:12.0pt;line-height:150%;font-family: 'Book Antiqua','serif',Garamond;Times New Roman'; color:black">Sample wording:</span></strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Garamond;Times New Roman';color:black"> [Name of individual] has received fees for serving as a speaker, a [</span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black">position; such as </span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Garamond;Times New Roman';color:black">consultant and/or an advisory board member] for [name(s) of organization(s)]. [Name of individual] has received research funding from [name(s) of organization(s)]. [Name of individual] is an employee of [name(s) of organization(s)]. [Name of individual] owns stocks and/or shares in [name(s) of organization(s)]. [Name of individual] owns patent [patent </span><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black">identifier information (including patent number, two-letter country code, and kind code) and a</span><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Garamond;Times New Roman';color:black"> brief description].</span></p> <p style="line-height:150%;"><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;">&nbsp;</span></strong><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond-Bold;">2.7 </span></strong><strong><span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',TimesNewRomanPS-BoldItalicMT;Times New Roman';color:black;">Data sharing statement<em>.</em></span></strong> <span style="font-size:12.0pt; line-height:150%;font-family: 'Book Antiqua','serif',Garamond;Times New Roman';color:black">Basic research and clinical research studies require a data sharing statement. The data sharing statement will be provided in the title page, and will be presented in the form as shown in the sample below.</span> </p> <p style="line-height:150%"><strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black">Sample wording: </span></strong><span style="font-size:12.0pt; line-height:150%;font-family:'Book Antiqua','serif';Times New Roman';color:black">Technical appendix, statistical code, and dataset available from the corresponding author at [email address or URL]. Participants gave informed consent for data sharing [or ...consent was not obtained but the presented data are anonymized and risk of identification is low... or consent was not obtained but the potential benefits of sharing these data outweigh the potential harms because...]&quot;. If no other data, please state: No additional data are available.</span></p> <p style="line-height:150%;layout-grid-mode:char;"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond-Bold;">2.8</span></strong> <a name="OLE_LINK7"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, TimesNewRomanPS-BoldItalicMT;">Biostatistics</span></strong></a><strong><em><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, TimesNewRomanPS-BoldItalicMT;">.</span></em></strong> <span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond;">Any manuscript describing a study (basic research and clinical research) that used biostatistics must include a statement in the Materials and Methods section affirming that the statistical review of the study was performed by a biomedical statistician. Statistical review is performed before the submission or after peer-review. The author invites an expert in Biomedical Statistics to evaluate the statistical method(s) used in the study, including but not limited to the </span><em><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond-Italic;">t-</span></em><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond;">test (group or paired comparisons), chi-square test, ridit, probit, logit and regression (linear, curvilinear, or stepwise) modeling, correlation, analysis of variance, and analysis of covariance. The review by the biomedical statistician is conducted with respect to the following points: (1) Statistical methods are adequately and appropriately described when they are used to verify the results; </span><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond;">(2) Statistical techniques are suitable or correct; and compliance with the following BPG directives;</span><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond;"> (3) Only homogeneous data can be averaged. Standard deviations are preferred to standard errors. The number of observations and subjects (</span><em><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond-Italic;">n</span></em><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond;">) is given. Losses in observations, such as drop-outs from the study, are reported; (4) Values, such as ED50, LD50 and IC50, have the 95% confidence limits calculated and have been compared by weighted probit modeling (using the functions described by Bliss and Finney); and (5) The word “significantly” is replaced by its synonyms (if it indicates extent) or the </span><em><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond-Italic;">P </span></em><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond;">value (if it indicates statistical significance). </span><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Arial;">Statistical data should be expressed as mean ± SD or mean ± SE. </span><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, &quot;Times New Roman&quot;;">Common statistical expressions</span> <span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;;">are identified </span><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Arial;">as follows: <em>t</em>-test as <em>t</em>; <em>F</em>-test as <em>F</em>; chi-square test as </span><em><span style="font-size:12.0pt;line-height:150%;font-family: Symbol,'Book Antiqua',Arial,Symbol;Book Antiqua';color:black;">c</span></em><em><sup><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Arial;">2</span></sup></em><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Arial;">; relative coefficient as <em>r</em>; degree of freedom as <em>df</em>; number of samples as <em>n</em>; and probability as <em>P</em>. </span></p> <p style="line-height:150%;layout-grid-mode:char;"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond;">Sample wording: </span></strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond;">The statistical methods of this study were reviewed by [name(s) of individual(s)] from [name(s) of organization(s)]…</span></p> <p style="line-height:150%; text-autospace:none"><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;, Garamond;">If a biostatistics editor is employed by the authors, the person’s name (first name and family (sur)name), qualifications, and contact information must be submitted to the editorial office in the form of a letter of confirmation of service. If the biostatistics editing was performed by a commercial service provider, the company’s name and contact information, including URL and E-mail or phone number, must be submitted to the editorial office in the form of a letter of confirmation of service. The letters of confirmation of service must include the corresponding author’s name (first name and family (sur)name) and contact information (E-mail and phone number), and the manuscript title.</span></p> <p style="line-height:150%"><strong><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;;">About BPG</span></strong></p> <p style="line-height:150%"><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;;">The BPG, founded on January 15, 1993, is a professional publisher of medical journals that is dedicated to discovering and disseminating knowledge under the precondition of complying with the standards and norms of scientific and medical publishing and all publishing and academic ethics.</span></p> <p style="line-height:150%"><span style="font-size: 12pt; line-height: 150%; font-family: &quot;Book Antiqua&quot;, &quot;serif&quot;;">BPG is committed to supporting CrossRef, 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