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Family therapy for depression is widely used, especially in the United Kingdom and the United States. The small number of randomised controlled trials included in the review were very heterogeneous, and therefore difficult to synthesise. Family therapy seems more effective than no treatment or being placed on a waiting list, but it remains unclear how effective this intervention is in comparison to other interventions. Further randomised controlled trials are needed. </p><div class="donate-box">If you found this evidence helpful, please consider donating to Cochrane. We are a charity that produces accessible evidence to help people make health and care decisions.<div class="donate-button"><a href="https://www.justgiving.com/cochranecollaboration" class="button-purple donate-button" target="_blank">Donate</a></div></div></div></div></div><div tabindex="7" class="required-fields group-abstract"><div class="field field-name-field-abstract-conclusion field-type-text-long field-label-above"> <div class="field-label">Authors' conclusions: </div> <div class="field-items"> <div class="field-item notranslate even"><p>The current evidence base is too heterogeneous and sparse to draw conclusions on the overall effectiveness of family therapy in the treatment of depression. At this point, use of psychological interventions for the treatment of depression for which there is already an evidence-base would seem to be preferable to family therapy. Further high quality trials examining the effectiveness and comparative effectiveness of explicitly defined forms of family therapy are required. </p></div> </div> <div id="abstract-read-more">Read the full abstract...</div> </div> <div class="field field-name-field-abstract-background field-type-text-long field-label-above"><div class="field-label">Background: </div><div class="field-items"><div class="field-item even"><p>People with depression often experience interpersonal problems. Family therapy for depression is a widely used intervention, but it is unclear whether this is an effective therapy for the treatment of depression.</p></div></div></div><div class="field field-name-field-abstract-objectives field-type-text-long field-label-above"><div class="field-label">Objectives: </div><div class="field-items"><div class="field-item even"><p>To assess the efficacy of family therapy for depression.</p></div></div></div><div class="field field-name-field-abstract-search-strategy field-type-text-long field-label-above"><div class="field-label">Search strategy: </div><div class="field-items"><div class="field-item even"><p>The following electronic databases were searched using a specific search strategy: CCDANCTR-Studies and CCDANCTR-References searched on 21/10/2005, The Cochrane Central Register of Controlled Trials, Medline (1966 to January 2005), EMBASE (1980 to January 2005), Psycinfo (1974 to January 2005). Reference lists of articles were also searched. Handsearches of relevant journals and bibliographies were conducted and first authors of included studies and experts in the field were contacted for further information.</p></div></div></div><div class="field field-name-field-abstract-criteria field-type-text-long field-label-above"><div class="field-label">Selection criteria: </div><div class="field-items"><div class="field-item even"><p>Included studies were randomised controlled and controlled clinical trials comparing family therapy with no intervention or an alternative intervention in which depression symptomatology was a main outcome measure. </p></div></div></div><div class="field field-name-field-abstract-data-collection field-type-text-long field-label-above"><div class="field-label">Data collection and analysis: </div><div class="field-items"><div class="field-item even"><p>Methodological quality was independently assessed by two review authors using the Maastricht-Amsterdam Criteria List. The qualitative and quantitative characteristics of the selected trials were independently extracted by three review authors using a standardised data extraction form. Levels of evidence were used to determine the strength of the evidence available. It was not possible to perform meta-analyses because of the heterogeneity of the selected studies. </p></div></div></div><div class="field field-name-field-abstract-main-results field-type-text-long field-label-above"><div class="field-label">Main results: </div><div class="field-items"><div class="field-item even"><p>Three high-quality and three low-quality studies, involving 519 people with depression, were identified. The studies were very heterogeneous in terms of interventions, participants, and measuring instruments. Despite fairly good methodological quality and positive findings of some studies, evidence for the effectiveness of family therapy for depression did not exceed level 3 (limited or conflicting evidence), except for moderate evidence (level 2), based on the non-combined findings from three studies, indicating that family therapy is more effective than no treatment or waiting list condition on decreasing depression, and on increasing family functioning. </p></div></div></div></div> </article> <div id="block-cck-blocks-field-terms-cochrane-library" class="block block-cck-blocks last even"> <div class="field field-name-field-terms-cochrane-library field-type-taxonomy-term-reference field-label-above clearfix"> <div class="field-label">Health topics: </div> <div class="field-items"> <div class="field-item even"><span><a href="/search/site?f%5B0%5D=field_terms_cochrane_library%253Aparents_all%3A51005" rel="noindex, nofollow">Mental health</a></span> > <span><a href="/search/site?f%5B0%5D=field_terms_cochrane_library%253Aparents_all%3A51023" rel="noindex, nofollow">Depression</a></span> > <span><strong><a href="/search/site?f%5B0%5D=field_terms_cochrane_library%253Aparents_all%3A51024" rel="noindex, nofollow">Depressive disorders & major depression</a></strong></span></div> </div> </div> </div> </div> <aside class="sidebars"> <section class="region region-sidebar-first column sidebar"> <div id="block-cck-blocks-field-version-published" class="block block-cck-blocks first odd"> <div class="field field-name-field-version-published field-type-date field-label-above"> <div class="field-label">Published: </div> <div class="field-item"> <span class="date-display-single">18 July 2007</span> </div> </div> </div> <div id="block-cck-blocks-field-authors" class="block block-cck-blocks even"> <div class="field field-name-field-authors field-type-text field-label-above"> <div class="field-label">Authors: </div> <div class="field-items notranslate"> Henken T, Huibers MJ.H., Churchill R, Restifo KK, Roelofs JJ </div> </div> </div> <div id="block-cck-blocks-field-doi" class="block block-cck-blocks odd"> <div id="library-link-review"> <a href="https://doi.wiley.com/10.1002/14651858.CD006728" target="_blank"> <div class="line1">See the full Review on</div> <div class="line2">the Cochrane Library</div> <div class="library-arrow">►</div> </a> </div> </div> <div id="article-actions" class="block"> <ul> <li class="active expandable purple" tabindex="18"><div class="icon icon-donate"> </div><div class="label"><div class="label-inner">Was this helpful? Donate.</div></div> <div id="donate-actions"><div class="inner">If you found this evidence helpful, please consider donating to Cochrane. We are a charity that produces accessible evidence to help people make health and care decisions.<div class="donate-button"><a href="https://www.justgiving.com/cochranecollaboration" class="button-purple" target="_blank">Donate</a></div></div></div> </li> <li class="active" tabindex="21"><a href="#print" id="print-link" target="_blank"><div class="icon icon-print"> </div><div class="label"><div class="label-inner">Print</div></div></a></li> <li class="active" tabindex="22"><a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD006728/epdf/abstract" id="pdf-link" target="_blank"><div class="icon icon-pdf"> </div><div class="label"><div class="label-inner">PDF</div></div></a></li> <li class="active expandable citation" tabindex="23"><div class="icon icon-cite"> </div><div class="label"><div class="label-inner">Citation</div></div><div id="citation"><div class="inner notranslate">Henken T, Huibers MJ.H., Churchill R, Restifo KK, Roelofs JJ. Family therapy for depression. Cochrane Database of Systematic Reviews 2007, Issue 3. Art. No.: CD006728. DOI: 10.1002/14651858.CD006728</div></div></li> </ul> </div> </section> <section class="region region-sidebar-second column sidebar"> <div id="block-block-40" class="block block-block first odd"> <script type='text/javascript' src='https://d1bxh8uas1mnw7.cloudfront.net/assets/embed.js'></script> <div data-badge-type="1" data-link-target="_blank" data-doi="10.1002/14651858.CD006728" data-hide-no-mentions="true" class="altmetric-embed"></div> <div class="altmetric-link"><a href="http://www.altmetric.com/details.php?domain=www.cochranelibrary.com&doi=10.1002/14651858.CD006728" target="_blank">Who is talking about this article?</a></div> </div><div id="block-block-14" class="block block-block last even"> <div><a class="button-purple" style="margin: 10px 0;" href="/our-evidence/what-are-systematic-reviews">Video: Systematic reviews explained</a></div> <div><a class="button-blue" style="margin: 10px 0;" href="/evidence">How our health evidence can help you</a></div> <div><a 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