CINXE.COM

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class="ds_title_table"> <h1 class="ds_title">Human CD11c/Integrin alpha X (NP_000878) VersaClone cDNA </h1> <div class="dsSprite_rnd ds_brand_logo ds_rnd_logo"></div> </div> <div class="product_meta"> <span class="category_number">Catalog #: RDC1094</span> <a href="/reviews/RDC1094" rel="nofollow"><span class="submit_review"><button class="btn btn-quaternary">Submit a Review</button></span></a> <span class="datasheet_link"> <a href="#product-datasheets">Datasheet / COA / SDS</a> </span> </div>  <div class="product_wrapper row"> <div class="product_ordering_wrapper col-xs-12 col-md-8 col-md-push-4"> <div class="product_ordering"> <form action="/products/human-cd11c-integrin-alpha-x-np-000878-versaclone-cdna_rdc1094" method="post" id="atc-datasheet-form" accept-charset="UTF-8"><div><div id="atc_datasheet_block">     <table class="add_to_cart"> <thead> <tr> <th class="ds_catalog">Catalog #</th> <th class="ds_availability_column mobile-hide">Availability</th> <th 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Upon receipt, store it immediately at the temperature recommended below.</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Storage</div> <div class="ds_table_cell summary_table_data">Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Species</div> <div class="ds_table_cell summary_table_data">Human</div> </div> </div> </div> </div> <div class="datasheet_section" id="product-datasheets"> <h2 id="ds_datasheets">Product Datasheets</h2> <div class="product_datasheets"> <span class="sds-message hide"> <p class="sds-label">You must select a language.</p> <span class="close_sds_message">x</span> </span> <div class="ds_document"> <a id="cfpdf" href="//resources.rndsystems.com/pdfs/datasheets/rdc1094.pdf?v=20241123" class="datasheets-link " target="_blank" rel="noreferrer nofollow">Product Datasheet</a> </div> <div class="ds_document"> <div class="ds_pdfData"><a class="datasheets-link" href="https://www.rndsystems.com/cofas/human-cd11c-integrin-alpha-x-np-000878-versaclone-cdna_rdc1094">COA</a> </div> </div> <div class="ds_document sds_link"> <a class="sds_non_cf datasheets-link non_cf_download_link" target="_blank" rel="noreferrer" data-path="//aero.bio-techne.com/sds/pdf/rdc1094?v=20241123">SDS</a> </div> </div> </div> <div id="customer_also_purchased_block" class="loader" data-catalogId="RDC1094"></div> <div id="ds_background" class="datasheet_section"> <h2>Background: CD11c</h2> <p>Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. They exist as heterodimers consisting of alpha and beta subunits. Some alpha and beta subunits exhibit specificity for one another and may be designated as a VLA (very late antigen) member. Heterodimers often preferentially bind certain cell adhesion molecules, or constituents of the ECM. Although they have no catalytic activity, integrins can be part of multimolecular signaling complexes known as focal adhesions.</p> <div class="ds_table background_table"> <div class="ds_table_body"> <div class="ds_table_row"> <div class="ds_table_cell background_table_name">Entrez Gene IDs</div> <div class="ds_table_cell background_table_data">3687 (Human); 16411 (Mouse); 64350 (Rat)</div> </div> <div class="ds_table_row"> <div class="ds_table_cell background_table_name">Alternate Names</div> <div class="ds_table_cell background_table_data">95 alpha chain; 95; 95, alpha subunit; CD11 antigen-like family member C; CD11c antigen; CD11c; CD11Cleu M5, alpha subunit; Integrin alpha X; integrin alpha-X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); ITGAX; Leu M5; Leukocyte adhesion glycoprotein p150; Leukocyte adhesion receptor p150; leukocyte surface antigen p150; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain; p150,95 alpha; SLEB6</div> </div> </div> </div> </div> <div id="ds_related_research_areas" class="datasheet_section"> <h2>Related Research Areas</h2> <ul class="ds_details"> <li> <a href="/research-area/adhesion-molecules">Adhesion Molecules</a> </li> <li> <a href="/research-area/adhesion-molecules-in-angiogenesis">Adhesion Molecules in Angiogenesis</a> </li> <li> <a href="/research-area/adhesive-interactions-in-allergy-and-asthma">Adhesive Interactions in Allergy and Asthma</a> </li> <li> <a href="/research-area/b-cell-chemotaxis--migration--and-adhesion">B Cell Chemotaxis, Migration, and Adhesion</a> </li> <li> <a href="/research-area/basophils">Basophils</a> </li> <li> <a href="/research-area/common-macrophage-markers">Common Macrophage Markers</a> </li> <li> <a href="/research-area/conventional-classical-dendritic-cells">Conventional/Classical Dendritic Cells</a> </li> <li> <a href="/research-area/granulocyte-markers">Granulocyte Markers</a> </li> <li> <a href="/research-area/inflammatory-monocyte--derived-dendritic-cells">Inflammatory/Monocyte-derived Dendritic Cells</a> </li> <li> <a href="/research-area/integrins-and-associated-molecules">Integrins and Associated Molecules</a> </li> <li> <a href="/research-area/isolation--culture--and-identification-of-natural-killer-cells">Isolation, Culture, and Identification of Natural Killer Cells</a> </li> <li> <a href="/research-area/langerhans-and-dermal-dendritic-cells">Langerhans and Dermal Dendritic Cells</a> </li> <li> <a href="/research-area/mdsc-phenotyping----negative-markers">MDSC Phenotyping - Negative Markers</a> </li> <li> <a href="/research-area/monocyte-markers">Monocyte Markers</a> </li> <li> <a href="/research-area/mouse-tissue--resident-macrophage-markers">Mouse Tissue-Resident Macrophage Markers</a> </li> <li> <a href="/research-area/plasmacytoid-dendritic-cells">Plasmacytoid Dendritic Cells</a> </li> <li> <a href="/research-area/t-cell-migration-adhesion">T Cell Migration/Adhesion</a> </li> </ul> </div> </div>    <div class="tab_content tab_4" data-tab="4" data-tabname="product-faqs" id="product-faqs"> <h2>FAQs</h2> <div class="row"> <div class="col-xs-12"> <p>No product specific FAQs exist for this product, however you may</p> <a class="btn btn-quinary view_all_faqs_btn" href="/resources/faqs/cdna-clones"> View all cDNA Clone FAQs </a> </div> </div> </div>   <div class="tab_content tab_6" data-tab="6" data-tabname="product-reviews" id="reviews"> <h3>Reviews for Human CD11c/Integrin alpha X (NP_000878) VersaClone cDNA</h3> <div class="row"> <div class="col-xs-12"> <div> <div class="row"> <div class="col-md-6"> <p>There are currently no reviews for this product. 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