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","tags":[{"term_id":685,"name":"Biology","slug":"biology","term_group":0,"term_taxonomy_id":685,"taxonomy":"research_areas","description":"","parent":0,"count":26,"filter":"raw"},{"term_id":704,"name":"Informatics and Data Standards","slug":"informatics-and-data-standards","term_group":0,"term_taxonomy_id":704,"taxonomy":"research_areas","description":"","parent":0,"count":18,"filter":"raw"}]},{"id":10773,"title":"Dr. J\u00fcri Reimand","url":"https:\/\/oicr.on.ca\/researchers\/dr-juri-reimand\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2016\/12\/juri-reimand-e1624979749917.jpg","excerpt":"The Reimand Lab develops and applies methods to interpret cancer data using pathway and network information.","tags":[{"term_id":685,"name":"Biology","slug":"biology","term_group":0,"term_taxonomy_id":685,"taxonomy":"research_areas","description":"","parent":0,"count":26,"filter":"raw"},{"term_id":704,"name":"Informatics and Data Standards","slug":"informatics-and-data-standards","term_group":0,"term_taxonomy_id":704,"taxonomy":"research_areas","description":"","parent":0,"count":18,"filter":"raw"}]},{"id":10766,"title":"Dr. Kristin Hope","url":"https:\/\/oicr.on.ca\/researchers\/dr-kristin-hope\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2016\/12\/kristin-hope-e1624979655135.jpg","excerpt":"Dr. Hope aims to identify the underlying processes that lead to the transformation of healthy cells into leukemic cells and contribute to the progression of the disease.","tags":[{"term_id":685,"name":"Biology","slug":"biology","term_group":0,"term_taxonomy_id":685,"taxonomy":"research_areas","description":"","parent":0,"count":26,"filter":"raw"},{"term_id":698,"name":"Treatment","slug":"treatment","term_group":0,"term_taxonomy_id":698,"taxonomy":"research_areas","description":"","parent":0,"count":23,"filter":"raw"}]},{"id":8648,"title":"Dr. Laurie Ailles","url":"https:\/\/oicr.on.ca\/researchers\/laurie-ailles\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2016\/12\/laura-ailes-banner-e1624979596640.jpg","excerpt":"Dr. Ailles and her team are focusing on three major research areas: identification of prognostic biomarkers and novel targets for head and neck squamous cell carcinoma (HNSCC) patients, epigenetics in clear cell renal cell carcinoma (ccRCC), an targeting cancer-associated fibroblasts (CAFs) in solid tumors.","tags":[{"term_id":685,"name":"Biology","slug":"biology","term_group":0,"term_taxonomy_id":685,"taxonomy":"research_areas","description":"","parent":0,"count":26,"filter":"raw"},{"term_id":705,"name":"Early Detection and Diagnosis","slug":"early-detection-and-diagnosis","term_group":0,"term_taxonomy_id":705,"taxonomy":"research_areas","description":"","parent":0,"count":21,"filter":"raw"},{"term_id":698,"name":"Treatment","slug":"treatment","term_group":0,"term_taxonomy_id":698,"taxonomy":"research_areas","description":"","parent":0,"count":23,"filter":"raw"}]},{"id":10480,"title":"Dr. Lillian Siu","url":"https:\/\/oicr.on.ca\/researchers\/lillian-siu\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2018\/10\/siuwide-e1624979470613.jpg","excerpt":"Dr. Siu is Co-Principal Investigator of the Ontario-wide Cancer TArgeted Nucleic Acid Evaluation (OCTANE) study.","tags":[{"term_id":698,"name":"Treatment","slug":"treatment","term_group":0,"term_taxonomy_id":698,"taxonomy":"research_areas","description":"","parent":0,"count":23,"filter":"raw"}]},{"id":10991,"title":"Dr. Lincoln Stein","url":"https:\/\/oicr.on.ca\/researchers\/dr-lincoln-stein\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2016\/12\/lincoln-stein.jpg","excerpt":"Dr. Stein is the Acting Scientific Director, and Head, Adaptive Oncology at OICR. ","tags":[{"term_id":685,"name":"Biology","slug":"biology","term_group":0,"term_taxonomy_id":685,"taxonomy":"research_areas","description":"","parent":0,"count":26,"filter":"raw"},{"term_id":707,"name":"Cancer Origins","slug":"cancer-origins","term_group":0,"term_taxonomy_id":707,"taxonomy":"research_areas","description":"","parent":0,"count":10,"filter":"raw"},{"term_id":705,"name":"Early Detection and Diagnosis","slug":"early-detection-and-diagnosis","term_group":0,"term_taxonomy_id":705,"taxonomy":"research_areas","description":"","parent":0,"count":21,"filter":"raw"}]},{"id":10994,"title":"Dr. Martin Yaffe","url":"https:\/\/oicr.on.ca\/researchers\/dr-martin-yaffe\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2016\/12\/martin-yaffe-e1624979164434.jpg","excerpt":"Dr. Yaffe researches the development and improvement of imaging techniques for the earlier detection, diagnosis and treatment of cancer.","tags":[{"term_id":705,"name":"Early Detection and Diagnosis","slug":"early-detection-and-diagnosis","term_group":0,"term_taxonomy_id":705,"taxonomy":"research_areas","description":"","parent":0,"count":21,"filter":"raw"},{"term_id":691,"name":"Imaging","slug":"imaging","term_group":0,"term_taxonomy_id":691,"taxonomy":"research_areas","description":"","parent":0,"count":6,"filter":"raw"}]},{"id":10763,"title":"Dr. Masoom Haider","url":"https:\/\/oicr.on.ca\/researchers\/dr-masoom-haider\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2018\/10\/Haider-2018.jpg","excerpt":" Dr. Haider\u2019s research focus is abdominal and pelvic MRI with an interest in therapeutic response assessment and quantitative imaging of cancer.","tags":[{"term_id":705,"name":"Early Detection and Diagnosis","slug":"early-detection-and-diagnosis","term_group":0,"term_taxonomy_id":705,"taxonomy":"research_areas","description":"","parent":0,"count":21,"filter":"raw"}]},{"id":21356,"title":"Dr. Masoud Vedadi","url":"https:\/\/oicr.on.ca\/researchers\/dr-masoud-vedadi\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2023\/01\/Masoud-Vedadi-1-1024x682.jpg","excerpt":"Dr. Vedadi is a Senior Scientific Advisor in the Drug Discovery Program.","tags":[{"term_id":1172,"name":"Drug discovery","slug":"drug-discovery","term_group":0,"term_taxonomy_id":1172,"taxonomy":"research_areas","description":"","parent":0,"count":1,"filter":"raw"}]},{"id":10481,"title":"Dr. Mathieu Lupien","url":"https:\/\/oicr.on.ca\/researchers\/dr-mathieu-lupien\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2018\/10\/Mathieu-e1624979100580.jpg","excerpt":"Dr. Lupien works to characterize and understand the role of noncoding regulatory elements as targets of genetic and epigenetic changes in oncogenesis.","tags":[{"term_id":685,"name":"Biology","slug":"biology","term_group":0,"term_taxonomy_id":685,"taxonomy":"research_areas","description":"","parent":0,"count":26,"filter":"raw"}]},{"id":21833,"title":"Dr. M\u00e9lanie Courtot","url":"https:\/\/oicr.on.ca\/researchers\/dr-melanie-courtot\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2023\/02\/Melanie-Courtot-scaled-e1676479554413-823x1024.jpg","excerpt":"Dr. M\u00e9lanie Courtot's team develops new software, databases and other necessary components to store, organize and compute over the large and complex datasets being generated by OICR\u2019s cancer research programs.","tags":[{"term_id":692,"name":"Informatics","slug":"informatics","term_group":0,"term_taxonomy_id":692,"taxonomy":"research_areas","description":"","parent":0,"count":3,"filter":"raw"},{"term_id":704,"name":"Informatics and Data Standards","slug":"informatics-and-data-standards","term_group":0,"term_taxonomy_id":704,"taxonomy":"research_areas","description":"","parent":0,"count":18,"filter":"raw"}]},{"id":14735,"title":"Dr. Melanie Spears","url":"https:\/\/oicr.on.ca\/researchers\/melanie-spears\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2021\/10\/mel-oicr-1-1024x1024.jpg","excerpt":"Dr. Spears is Interim Co-Director, Diagnostic Development. Her research focuses novel approaches to translate scientific research into innovative treatment approaches.","tags":[{"term_id":685,"name":"Biology","slug":"biology","term_group":0,"term_taxonomy_id":685,"taxonomy":"research_areas","description":"","parent":0,"count":26,"filter":"raw"},{"term_id":686,"name":"Biomarkers","slug":"biomarkers","term_group":0,"term_taxonomy_id":686,"taxonomy":"research_areas","description":"","parent":0,"count":4,"filter":"raw"},{"term_id":687,"name":"Diagnostics","slug":"diagnostics","term_group":0,"term_taxonomy_id":687,"taxonomy":"research_areas","description":"","parent":0,"count":3,"filter":"raw"}]},{"id":16350,"title":"Dr. Methvin Isaac","url":"https:\/\/oicr.on.ca\/researchers\/methvin-isaac\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2022\/02\/methvin.jpg","excerpt":"Dr. Isaac investigates the Hippo-pathway and the integrated stress response pathway that cancers exploit.","tags":[{"term_id":693,"name":"Therapeutics","slug":"therapeutics","term_group":0,"term_taxonomy_id":693,"taxonomy":"research_areas","description":"","parent":0,"count":5,"filter":"raw"}]},{"id":10765,"title":"Dr. Naoto Hirano","url":"https:\/\/oicr.on.ca\/researchers\/dr-naoto-hirano\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2021\/02\/Naoto-hirano.jpg","excerpt":"The overarching goal of Dr. Hirano\u2019s research is to devise novel anti-tumour immunotherapeutic modalities that can cure cancer.","tags":[{"term_id":698,"name":"Treatment","slug":"treatment","term_group":0,"term_taxonomy_id":698,"taxonomy":"research_areas","description":"","parent":0,"count":23,"filter":"raw"}]},{"id":10478,"title":"Dr. Parisa Shooshtari","url":"https:\/\/oicr.on.ca\/researchers\/parisa-shooshtari\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2019\/08\/Parisa-Shooshtari-web-e1624978926323.jpg","excerpt":"Dr. Shooshtari develops computational and statistical methods to understand the cellular and molecular mechanisms of complex diseases.","tags":[{"term_id":685,"name":"Biology","slug":"biology","term_group":0,"term_taxonomy_id":685,"taxonomy":"research_areas","description":"","parent":0,"count":26,"filter":"raw"},{"term_id":704,"name":"Informatics and Data Standards","slug":"informatics-and-data-standards","term_group":0,"term_taxonomy_id":704,"taxonomy":"research_areas","description":"","parent":0,"count":18,"filter":"raw"}]},{"id":8652,"title":"Dr. Philip Awadalla","url":"https:\/\/oicr.on.ca\/researchers\/philip-awadalla\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2018\/03\/philip-awadalla-e1624978824382.jpg","excerpt":"Dr. Awadalla focuses on the development of genomics approaches, model-based tools and population-based approaches to study mutation rates, genome biology and 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study.","tags":[{"term_id":685,"name":"Biology","slug":"biology","term_group":0,"term_taxonomy_id":685,"taxonomy":"research_areas","description":"","parent":0,"count":26,"filter":"raw"},{"term_id":698,"name":"Treatment","slug":"treatment","term_group":0,"term_taxonomy_id":698,"taxonomy":"research_areas","description":"","parent":0,"count":23,"filter":"raw"}]},{"id":13174,"title":"Dr. Raymond Kim","url":"https:\/\/oicr.on.ca\/researchers\/dr-raymond-kim\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2021\/08\/RKim-963x1024.jpg","excerpt":"Dr. Raymond Kim leads OICR\u2019s Ontario Hereditary Cancer Research Network.","tags":[{"term_id":689,"name":"Genomics","slug":"genomics","term_group":0,"term_taxonomy_id":689,"taxonomy":"research_areas","description":"","parent":0,"count":4,"filter":"raw"}]},{"id":8649,"title":"Dr. Rima Al-awar","url":"https:\/\/oicr.on.ca\/researchers\/rima-al-awar\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2021\/06\/Rima-sq.jpg","excerpt":"Dr. Al-awar founded the OICR Drug Discovery Program and she now serves as a Senior Advisor to OICR.","tags":[{"term_id":698,"name":"Treatment","slug":"treatment","term_group":0,"term_taxonomy_id":698,"taxonomy":"research_areas","description":"","parent":0,"count":23,"filter":"raw"}]},{"id":10474,"title":"Dr. Robert Rottapel","url":"https:\/\/oicr.on.ca\/researchers\/robert-rottapel\/","image":"https:\/\/oicr.on.ca\/wp-content\/uploads\/2018\/12\/rottapelwide-e1624978724609.jpg","excerpt":"The Rottapel Lab uses functional genetic screens, identifying novel vulnerabilities in ovarian cancer to develop new therapeutic targets.","tags":[{"term_id":698,"name":"Treatment","slug":"treatment","term_group":0,"term_taxonomy_id":698,"taxonomy":"research_areas","description":"","parent":0,"count":23,"filter":"raw"}]},{"id":12595,"title":"Dr. Rola 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class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-1 wp-block-columns-is-layout-flex"> <div class="wp-block-column pb-0 is-layout-flow wp-block-column-is-layout-flow" style="flex-basis:100%"> <p class="text-large">At OICR, our research helps people live better, makes research work better and harnesses the power of Ontario innovation to keep Ontario a world leader in cancer research and care.</p> </div> </div> </div></div> <div class="p-0 wp-block-group"> <div class="wp-block-group__inner-container"> <div class="oicr-separator bar"></div> </div> </div> <div style="height:40px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-group pb-0 pt-0"><div class="wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained"> <div class="wp-block-columns pb-0 pt-0 is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column pb-0 pt-0 is-layout-flow wp-block-column-is-layout-flow"><div class="wp-block-image"> <figure class="alignright size-full is-resized"><img fetchpriority="high" decoding="async" src="https://oicr.on.ca/wp-content/uploads/2023/05/family.jpg" alt="" class="wp-image-23137" width="400" height="294" srcset="https://oicr.on.ca/wp-content/uploads/2023/05/family.jpg 800w, https://oicr.on.ca/wp-content/uploads/2023/05/family-300x220.jpg 300w, https://oicr.on.ca/wp-content/uploads/2023/05/family-768x564.jpg 768w" sizes="(max-width: 400px) 100vw, 400px" /></figure></div> <p class="text-large"><strong>Helping people live better</strong></p> <p class="text-large">Our innovations in detecting, diagnosing and treating cancer give people a better chance at surviving cancer and living healthier lives.</p> <div style="height:6px" aria-hidden="true" class="wp-block-spacer"></div> </div> </div> </div></div> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-3 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/t-cell.png" alt="Life-changing made-in-Canada immunotherapy."> <div class="mb-3 font-bold leading-tight text-18">Life-changing made-in-Canada immunotherapy.</div> <div class="leading-relaxed text-14"><p class="p1">Canada’s first platform to manufacture CAR-T cells – immune cells trained to kill cancer – is delivering results for Canadians with blood cancers. Multiple patients are cancer-free after an OICR-supported clinical trial. The platform also makes therapy more affordable by manufacturing CAR T-cells at the point of care.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/made-in-canada-car-t-cells-save-lives-in-promising-clinical-trial/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/pancreas.png" alt="Personalized treatment for deadly pancreatic cancer."> <div class="mb-3 font-bold leading-tight text-18">Personalized treatment for deadly pancreatic cancer.</div> <div class="leading-relaxed text-14"><p class="p1">A new OICR clinical trial builds on years of research into Canada’s third deadliest cancer. Tumour samples are being tested against OICR’s world-leading pancreatic cancer database for genetic clues on potential treatments, with results delivered in time to influence patient care.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/programs/pancreatic-cancer-translational-research-initiative-pancurx/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> </div> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-4 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/scan.png" alt="More efficient prostate cancer therapy."> <div class="mb-3 font-bold leading-tight text-18">More efficient prostate cancer therapy.</div> <div class="leading-relaxed text-14"><p class="p1">Treating prostate cancer with radiation can involve up to 28 doses over several weeks. But an OICR-funded clinical trial is using two imaging tools to deliver radiation so precisely it may only take five doses. OICR is also using this combination to spot cancer relapse earlier without painful biopsies.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/prostate-cancer-trial-aims-to-deliver-shorter-more-effective-radiotherapy-thanks-to-advanced-imaging/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/brain.png" alt="Faster, more affordable brain tumour diagnosis."> <div class="mb-3 font-bold leading-tight text-18">Faster, more affordable brain tumour diagnosis.</div> <div class="leading-relaxed text-14"><p class="p1">Diagnosing brain tumours often means sending samples to one of the few centres with expensive molecular testing equipment. But a new molecular test created by OICR researchers can help diagnose brain tumours in less than half the time of existing systems for a fraction of the cost.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/low-cost-molecular-test-targets-more-efficient-brain-cancer-diagnosis/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> <p> </p> </div> </div> </div> </div> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-5 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/molecule-diag.png" alt="State-of-the-art breast cancer diagnostics."> <div class="mb-3 font-bold leading-tight text-18">State-of-the-art breast cancer diagnostics.</div> <div class="leading-relaxed text-14"><p class="p1">Two molecular tests developed by OICR researchers can help predict if breast cancer will recur after treatment, and if chemotherapy will be effective against it. The tests have earned international patents and are on their way toward improving breast cancer outcomes and quality of life for women.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/precision-diagnostics-predict-risk-and-response-to-breast-cancer-therapies/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/medication.png" alt="Clinical and pharma collaborations to test pre-surgery treatment."> <div class="mb-3 font-bold leading-tight text-18">Clinical and pharma collaborations to test pre-surgery treatment.</div> <div class="leading-relaxed text-14"><p>A multidisciplinary OICR-led network has launched five clinical trials where participants receive new therapies during the time between their cancer diagnosis and their initial surgery. These trials give trial participants early access to cutting-edge therapies while allowing researchers to study their effect on tumours after they are removed.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/programs/window-of-opportunity-network/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> </div> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-6 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/ultrasound.png" alt="3D ultrasound to diagnose and treat cancer."> <div class="mb-3 font-bold leading-tight text-18">3D ultrasound to diagnose and treat cancer.</div> <div class="leading-relaxed text-14"><p class="p1">A 3D ultrasound system developed by OICR-supported researchers can improve breast cancer screening by accurately and cost-effectively spotting cancer in women with dense breasts, whose cancer is often ‘masked’ in traditional mammograms. OICR scientists are also using <a href="https://oicr.on.ca/making-liver-cancer-ablations-more-accurate-with-3d-ultrasound-guidance/">3D ultrasound to make thermal ablation procedures to treat liver cancer more accurate</a>.</p> <p> </p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/adding-another-dimension-to-breast-cancer-screening/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/literature.png" alt="Evidence for national anti-smoking policy. "> <div class="mb-3 font-bold leading-tight text-18">Evidence for national anti-smoking policy. </div> <div class="leading-relaxed text-14"><p>U.S. lawmakers cited an OICR study when announcing their country’s upcoming ban on menthol cigarettes. The study evaluated a similar ban in Canada that came into effect between 2015 and 2018, estimating that a policy to ban menthols in the U.S. could cause 1.3 million more Americans to quit smoking.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/building-evidence-for-the-landmark-u-s-ban-on-menthol-cigarettes/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> </div> <div style="height:40px" aria-hidden="true" class="wp-block-spacer"></div> <div class="p-0 wp-block-group"> <div class="wp-block-group__inner-container"> <div class="oicr-separator bar"></div> </div> </div> <div style="height:40px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-7 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"><div class="wp-block-image"> <figure class="alignright size-full is-resized"><img decoding="async" src="https://oicr.on.ca/wp-content/uploads/2023/05/research.jpg" alt="" class="wp-image-23149" width="400" height="294" srcset="https://oicr.on.ca/wp-content/uploads/2023/05/research.jpg 1000w, https://oicr.on.ca/wp-content/uploads/2023/05/research-300x220.jpg 300w, https://oicr.on.ca/wp-content/uploads/2023/05/research-768x564.jpg 768w" sizes="(max-width: 400px) 100vw, 400px" /></figure></div> <p class="text-large"><strong>Making research work better</strong></p> <p class="text-large">The partnerships and infrastructure we’ve built empower Ontario’s world-leading scientists make life-changing discoveries.</p> <div style="height:6px" aria-hidden="true" class="wp-block-spacer"></div> </div> </div> </div></div> <div class="wp-block-group pt-0 pb-0"><div class="wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow"> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/OHCRN-2.png" alt="A world-class approach against hereditary cancers."> <div class="mb-3 font-bold leading-tight text-18">A world-class approach against hereditary cancers.</div> <div class="leading-relaxed text-14"><p class="p1">OICR is creating a Canada-first network to find hereditary cancers earlier and match patients with treatments. The network has inspired a similar approach in the UK, and network leaders helped develop tools and criteria for standardized hereditary cancer testing that were adopted across Ontario.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/programs/ontario-hereditary-cancer-research-network/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/trials.png" alt="Better access to cancer clinical trials."> <div class="mb-3 font-bold leading-tight text-18">Better access to cancer clinical trials.</div> <div class="leading-relaxed text-14"><p>Cancer clinical trial recruitment is up 130 per cent in Ontario since OICR created the Canadian Cancer Clinical Trials Network (3CTN). The network has launched several programs to match patients with trials and is piloting clinical trial ‘satellite sites’ in remote communities to reduce travel times and expenses for participants.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://3ctn.ca/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> </div> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/OHCRN-2.png" alt="Genomics capacity for personalized care."> <div class="mb-3 font-bold leading-tight text-18">Genomics capacity for personalized care.</div> <div class="leading-relaxed text-14"><p>OICR has scaled up Ontario’s capacity for precision medicine, where treatment is tailored to a person’s genetics. Our genomics lab earned world-class accreditation that allows it to influence patient care, we secured Canada’s first state-of-the-art genome sequencer, and we are expanding our Joint Genomics Program across the province.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://genomics.oicr.on.ca/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/data-share.png" alt="Global data sharing to advance genomic medicine."> <div class="mb-3 font-bold leading-tight text-18">Global data sharing to advance genomic medicine.</div> <div class="leading-relaxed text-14"><p>OICR founded and hosts the Global Alliance for Genomics and Health (GA4GH), which has members in 90+ countries. GA4GH created international data <a href="https://pubmed.ncbi.nlm.nih.gov/35072136/">sharing standards</a> to help harness genomics data to benefit all populations<strong>. </strong>OICR scientists also <a href="https://ascopubs.org/doi/full/10.1200/PO.22.00245">provided guidance</a> for countries on integrating genomic sequencing into their healthcare systems.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/programs/global-alliance-for-genomics-and-health/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> </div> </div></div> <div style="height:40px" aria-hidden="true" class="wp-block-spacer"></div> <div class="p-0 wp-block-group"> <div class="wp-block-group__inner-container"> <div class="oicr-separator bar"></div> </div> </div> <div style="height:40px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-group pt-0 pb-0"><div class="wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow"> <div class="wp-block-group pt-0 pb-0"><div class="wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow"> <div class="wp-block-columns pb-0 is-layout-flex wp-container-core-columns-is-layout-10 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="flex-basis:100%"><div class="wp-block-image"> <figure class="alignright size-full is-resized"><img decoding="async" src="https://oicr.on.ca/wp-content/uploads/2017/01/busy-lab.jpg" alt="" class="wp-image-9079" width="400" srcset="https://oicr.on.ca/wp-content/uploads/2017/01/busy-lab.jpg 440w, https://oicr.on.ca/wp-content/uploads/2017/01/busy-lab-300x147.jpg 300w" sizes="(max-width: 440px) 100vw, 440px" /></figure></div> <p class="text-title-med">Harnessing Ontario innovations</p> <p class="text-large">Our support helps made-in-Ontario ideas grow into Ontario-based companies that create jobs and fuel the province’s economy.</p> </div> </div> </div></div> <div class="wp-block-columns pt-0 is-layout-flex wp-container-core-columns-is-layout-11 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/invest.png" alt="$1.5 billion into Ontario’s economy."> <div class="mb-3 font-bold leading-tight text-18">$1.5 billion into Ontario’s economy.</div> <div class="leading-relaxed text-14"><p>The total investments attracted to Ontario’s life sciences sector by FACIT’s portfolio of biotechnology start-ups reached $1.5 billion in 2023. This milestone has doubled since 2019 and represents a 30-fold leverage from the private sector for FACIT investments.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://facit.ca/news/facit-generates-1-5-billion-in-follow-on-investment#post-9966"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/doctorandsupport.png" alt="Ontario entrepreneurs bringing cancer discoveries to patients. "> <div class="mb-3 font-bold leading-tight text-18">Ontario entrepreneurs bringing cancer discoveries to patients. </div> <div class="leading-relaxed text-14"><p>FACIT’s investment programs have helped Ontario <a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Foicr.on.ca%2Ffrom-idea-to-impact-an-expanding-solution-to-a-common-surgical-problem%2F&data=05%7C01%7CDaniel.Punch%40oicr.on.ca%7C7116821511b74ba861bb08db44ec6c67%7C9df949f8a6eb419d9caa1f8c83db674f%7C0%7C0%7C638179554440463219%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=%2B9hIKUf9evDo5fCivGoLFzUxCQfnBuZ3I6j4ShB1nhU%3D&reserved=0">start-ups like Xpan</a> advance their cancer innovations. With FACIT support, Xpan has progressed its minimally invasive surgical access port from proof-of-concept to a functional technology, and has now submitted for marketing approval with the U.S. FDA – a significant biotech milestone.</p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://oicr.on.ca/facit-pitch-competition-empowers-ontarios-oncology-entrepreneurs/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow"> <div class="px-8 py-10 transition duration-300 border-t border-gray-100 shadow-md hover:shadow-lg card-component"> <img decoding="async" class="object-cover mb-6 rounded-full w-28 h-28" src="https://oicr.on.ca/wp-content/uploads/2023/05/grow.png" alt="Sustainable Ontario biotech companies."> <div class="mb-3 font-bold leading-tight text-18">Sustainable Ontario biotech companies.</div> <div class="leading-relaxed text-14"><p>Nearly half of FACIT-supported innovations have received follow-on funding and more than 85% are being developed into products. This includes Fusion Pharmaceuticals, which achieved one of Ontario biotech’s largest ever IPOs, and <a href="https://facit.ca/news/ctrl-therapeutics-a-facit-backed-start-up-raises-us10m-to-develop-autologous-cell-therapy-for-patients-living-with-cancer#post-9906">Turnstone Biologics,</a> which received a US<a href="https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.businesswire.com%2Fnews%2Fhome%2F20210721005371%2Fen%2FTurnstone-Biologics-Raises-80-Million-Series-D-Financing&data=05%7C01%7CDaniel.Punch%40oicr.on.ca%7C7116821511b74ba861bb08db44ec6c67%7C9df949f8a6eb419d9caa1f8c83db674f%7C0%7C0%7C638179554440463219%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=4l1v5mptkv%2BJSWTcGRt0%2BZkdGpbsU4mDA7oEyYeLVWc%3D&reserved=0">$80 million Series D.</a></p> <p> </p> <div class="button-wrapper text-left"> <a class="w-icon bg-green oicr-button" target="" href="https://facit.ca/"> <div class="title">Read more</div> <svg class="w-3 fill-current" xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 12 19"><path class="fill-current" fill="#fff" fill-rule="evenodd" d="M1.088 1.145a1.25 1.25 0 00.057 1.767L8.172 9.5l-7.027 6.588a1.25 1.25 0 101.71 1.824L11.828 9.5 2.855 1.088a1.25 1.25 0 00-1.767.057z" clip-rule="evenodd"/></svg> </a></div> </div> </div> </div> </div> </div></div> <div style="height:100px" aria-hidden="true" class="wp-block-spacer"></div> <div class="bg-gray-200 border-t border-b border-gray-200 anim buttons-wrapper md:grid gap-px md:grid-cols-2"> <a class="block py-6 bg-white px-30px hover:bg-gray-100 line-group line-2px transition duration-300 md:px-0 post border-b border-gray-200 md:border-b-0" href="https://oicr.on.ca/about/commercialization-and-facit/"> <div class="inline-flex w-full items-center "> <div class="md:px-8"> <svg class="w-5 mr-6 md:mr-0" viewBox="0 0 24 73" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M23 72L0.999998 36.5L23 1" 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