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Lilly expands manufacturing footprint in Ireland
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class="menu-item search"><a href="#" class="search-toggle"><i class="icon-search"></i></a></li></ul></div></nav><div style="padding-top:10px;text-align:center"><div id='div-gpt-pharma_largeleader'> <script> googletag.cmd.push(function() { googletag.display('div-gpt-pharma_largeleader'); }); </script> </div></div><div class="site-inner"><div class="wrap"><div class="content-sidebar-wrap"><main class="content"><article class="type-post entry" aria-label="Lilly expands manufacturing footprint in Ireland"><header class="entry-header"><h1 class="entry-title">Lilly expands manufacturing footprint in Ireland</h1> <p class="entry-meta"><span class="entry-author">By <a href="https://www.pharmaceuticalprocessingworld.com/author/cnewmarker/" class="entry-author-link" rel="author"><span class="entry-author-name">Chris Newmarker</span></a></span> | <time class="entry-time">September 17, 2024</time></p></header><div class="entry-content"><p><img decoding="async" class="alignright size-medium wp-image-14204" src="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2021/01/Eli_Lilly_and_Company-1-300x195.jpg" alt="This is the logo of Eli Lilly." width="300" height="195" srcset="https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2021/01/Eli_Lilly_and_Company-1-300x195.jpg 300w, https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2021/01/Eli_Lilly_and_Company-1-768x499.jpg 768w, https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2021/01/Eli_Lilly_and_Company-1-368x238.jpg 368w, https://www.pharmaceuticalprocessingworld.com/wp-content/uploads/2021/01/Eli_Lilly_and_Company-1.jpg 770w" sizes="(max-width: 300px) 100vw, 300px" />Eli Lilly and Co. recently announced that it’s spending $1 billion to expand its Limerick, Ireland, manufacturing site.</p> <p>The goal of the expansion, announced Sept. 12, is to increase the production of biologic active ingredients, including those for the company’s recently approved treatment for early symptomatic Alzheimer’s disease. The company announced in July that the FDA has approved Kisunla (donanemab-azbt, 350 mg/20 mL once-monthly injection for IV infusion), an amyloid plaque-targeting therapy that could be stopped when amyloid plaques are removed.</p> <p>“Alzheimer’s disease is a devastating diagnosis for both the patient and for their loved ones, along with having a huge burden on society,” Anne E. White, EVP and president of Lilly Neuroscience, said in a news release. “The treatments we will make here in Limerick offer the potential to be able to slow the progression of the disease and make life better for millions of people around the world.”</p> <p>Here’s more from Lilly about the Limerick project:</p> <blockquote><p>“Today’s announcement brings Lilly’s total Limerick investment to $2 billion, doubling the investment the company announced in March 2023. Advanced technologies such as machine learning, AI and automated robotics and systems at the site will enable right-first-time execution, all in support of the safe and reliable supply of medicines. As a part of this expansion, Lilly will create another 150 jobs for highly skilled workers in Limerick such as engineers, scientists, quality assurance professionals and operations personnel, for a total of 450 employees. Lilly initially announced the Limerick site in 2022 and broke ground in March 2023. Production of biologic active ingredients for Lilly medicines is on track to start in 2026.”</p></blockquote> <h3>Lilly is engaged in a major expansion project</h3> <p>Lilly has also unveiled its new $800 million facility expansion in Kinsale, Ireland. The expanded Kinsale site started making medicines last year to meet demand for Lilly’s latest diabetes and obesity treatments. For example, last year, Lilly<a href="https://investor.lilly.com/news-releases/news-release-details/zepboundtm-tirzepatide-now-available-us-pharmacies-adults-living"> made Zepbound (tirzepatide) available in the U.S.</a> for treating obesity in adults; Zepbound activates both GIP and GLP-1 hormone receptors.</p> <p>The additional investment in Ireland is part of Lilly’s major manufacturing expansion. The Indianapolis-based company has spent more than $20 billion since 2020 to build, expand and acquire manufacturing facilities in the U.S. and Europe.</p> <p>“These investments will boost the production of some of our medicines, helping millions of people with diabetes, obesity and Alzheimer’s disease live the healthiest lives possible,” said Edgardo Hernandez, EVP and president of Lilly Manufacturing Operations. “We won’t stop there — these state-of-the-art facilities will also be equipped to support our promising pipeline molecules of the future.”</p> <!--<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:trackback="http://madskills.com/public/xml/rss/module/trackback/"> <rdf:Description rdf:about="https://www.pharmaceuticalprocessingworld.com/lilly-expands-manufacturing-footprint-in-ireland/" dc:identifier="https://www.pharmaceuticalprocessingworld.com/lilly-expands-manufacturing-footprint-in-ireland/" dc:title="Lilly expands manufacturing footprint in Ireland" trackback:ping="https://www.pharmaceuticalprocessingworld.com/lilly-expands-manufacturing-footprint-in-ireland/trackback/" /> </rdf:RDF>--> </div><footer class="entry-footer"></footer></article><section id="custom_html-10" class="widget_text widget widget_custom_html"><div class="widget_text widget-wrap"><div class="textwidget custom-html-widget"><div id="trendmd-suggestions"></div></div></div></section> <div class="author-box"><h4 class="block-header">About The Author</h4><div class="author-box-content"><img alt='' src='https://secure.gravatar.com/avatar/bcec739a5f1ba9600a33099ba78f5710?s=168&d=mm&r=g' srcset='https://secure.gravatar.com/avatar/bcec739a5f1ba9600a33099ba78f5710?s=336&d=mm&r=g 2x' class='avatar avatar-168 photo' height='168' width='168' loading='lazy' decoding='async'/><h5>Chris Newmarker</h5><p>Chris Newmarker is the executive editor of WTWH Media life science's news websites and publications including MassDevice, Medical Design & Outsourcing and more. A professional journalist of 18 years, he is a veteran of UBM (now Informa) and The Associated Press whose career has taken him from Ohio to Virginia, New Jersey and, most recently, Minnesota. He’s covered a wide variety of subjects, but his focus over the past decade has been business and technology. He holds bachelor’s degrees in journalism and political science from Ohio State University. Connect with him on <a href="https://www.linkedin.com/in/chrisnewmarker/">LinkedIn</a> or email at cnewmarker@wtwhmedia.com.</p> <p class="socials"><a href="https://www.linkedin.com/in/chrisnewmarker/" target="_blank" rel="noopener noreferrer"><i class="icon-url"></i></a> <a href="https://twitter.com/newmarker" target="_blank" rel="noopener noreferrer"><i class="icon-twitter"></i></a></p></div></div> <div id="respond" class="comment-respond"> <h3 id="reply-title" class="comment-reply-title">Tell Us What You Think! <small><a rel="nofollow" id="cancel-comment-reply-link" href="/lilly-expands-manufacturing-footprint-in-ireland/#respond" style="display:none;">Cancel reply</a></small></h3><form action="https://www.pharmaceuticalprocessingworld.com/wp-comments-post.php?wpe-comment-post=pharmp" method="post" id="commentform" class="comment-form" novalidate><p class="comment-form-comment"><label for="comment">Comment <span class="required">*</span></label> <textarea placeholder="Enter your 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e({values:Mr(t,e.normalizeUnit),loc:xi.fromObject(n),conversionAccuracy:n.conversionAccuracy})},e.fromDurationLike=function(t){if(or(t))return e.fromMillis(t);if(e.isDuration(t))return t;if("object"==typeof t)return e.fromObject(t);throw new Fn("Unknown duration argument "+t+" of type "+typeof t)},e.fromISO=function(t,n){var r=Mi(t,[Pi,Yi])[0];return r?e.fromObject(r,n):e.invalid("unparsable",'the input "'+t+"\" can't be parsed as ISO 8601")},e.fromISOTime=function(t,n){var r=Mi(t,[ji,oo])[0];return r?e.fromObject(r,n):e.invalid("unparsable",'the input "'+t+"\" can't be parsed as ISO 8601")},e.invalid=function(t,n){if(void 0===n&&(n=null),!t)throw new Fn("need to specify a reason the Duration is invalid");var r=t instanceof Hr?t:new Hr(t,n);if(li.throwOnInvalid)throw new In(r);return new e({invalid:r})},e.normalizeUnit=function(e){var t={year:"years",years:"years",quarter:"quarters",quarters:"quarters",month:"months",months:"months",week:"weeks",weeks:"weeks",day:"days",days:"days",hour:"hours",hours:"hours",minute:"minutes",minutes:"minutes",second:"seconds",seconds:"seconds",millisecond:"milliseconds",milliseconds:"milliseconds"}[e?e.toLowerCase():e];if(!t)throw new Cn(e);return t},e.isDuration=function(e){return e&&e.isLuxonDuration||!1};var t=e.prototype;return t.toFormat=function(e,t){void 0===t&&(t={});var n=gn({},t,{floor:!1!==t.round&&!1!==t.floor});return this.isValid?Ur.create(this.loc,n).formatDurationFromString(this,e):"Invalid Duration"},t.toHuman=function(e){var t=this;void 0===e&&(e={});var n=ho.map((function(n){var r=t.values[n];return ir(r)?null:t.loc.numberFormatter(gn({style:"unit",unitDisplay:"long"},e,{unit:n.slice(0,-1)})).format(r)})).filter((function(e){return e}));return this.loc.listFormatter(gn({type:"conjunction",style:e.listStyle||"narrow"},e)).format(n)},t.toObject=function(){return this.isValid?gn({},this.values):{}},t.toISO=function(){if(!this.isValid)return null;var e="P";return 0!==this.years&&(e+=this.years+"Y"),0===this.months&&0===this.quarters||(e+=this.months+3*this.quarters+"M"),0!==this.weeks&&(e+=this.weeks+"W"),0!==this.days&&(e+=this.days+"D"),0===this.hours&&0===this.minutes&&0===this.seconds&&0===this.milliseconds||(e+="T"),0!==this.hours&&(e+=this.hours+"H"),0!==this.minutes&&(e+=this.minutes+"M"),0===this.seconds&&0===this.milliseconds||(e+=yr(this.seconds+this.milliseconds/1e3,3)+"S"),"P"===e&&(e+="T0S"),e},t.toISOTime=function(e){if(void 0===e&&(e={}),!this.isValid)return null;var t=this.toMillis();if(t<0||t>=864e5)return null;e=gn({suppressMilliseconds:!1,suppressSeconds:!1,includePrefix:!1,format:"extended"},e);var n=this.shiftTo("hours","minutes","seconds","milliseconds"),r="basic"===e.format?"hhmm":"hh:mm";e.suppressSeconds&&0===n.seconds&&0===n.milliseconds||(r+="basic"===e.format?"ss":":ss",e.suppressMilliseconds&&0===n.milliseconds||(r+=".SSS"));var i=n.toFormat(r);return e.includePrefix&&(i="T"+i),i},t.toJSON=function(){return this.toISO()},t.toString=function(){return this.toISO()},t.toMillis=function(){return this.as("milliseconds")},t.valueOf=function(){return this.toMillis()},t.plus=function(t){if(!this.isValid)return this;for(var n,r=e.fromDurationLike(t),i={},o=Dn(ho);!(n=o()).done;){var s=n.value;(lr(r.values,s)||lr(this.values,s))&&(i[s]=r.get(s)+this.get(s))}return yo(this,{values:i},!0)},t.minus=function(t){if(!this.isValid)return this;var n=e.fromDurationLike(t);return this.plus(n.negate())},t.mapUnits=function(e){if(!this.isValid)return this;for(var t={},n=0,r=Object.keys(this.values);n<r.length;n++){var i=r[n];t[i]=Tr(e(this.values[i],i))}return yo(this,{values:t},!0)},t.get=function(t){return this[e.normalizeUnit(t)]},t.set=function(t){return this.isValid?yo(this,{values:gn({},this.values,Mr(t,e.normalizeUnit))}):this},t.reconfigure=function(e){var t=void 0===e?{}:e,n=t.locale,r=t.numberingSystem,i=t.conversionAccuracy,o={loc:this.loc.clone({locale:n,numberingSystem:r})};return i&&(o.conversionAccuracy=i),yo(this,o)},t.as=function(e){return this.isValid?this.shiftTo(e).get(e):NaN},t.normalize=function(){if(!this.isValid)return this;var e=this.toObject();return function(e,t){mo.reduce((function(n,r){return ir(t[r])?n:(n&&vo(e,t,n,t,r),r)}),null)}(this.matrix,e),yo(this,{values:e},!0)},t.shiftTo=function(){for(var t=arguments.length,n=new Array(t),r=0;r<t;r++)n[r]=arguments[r];if(!this.isValid)return this;if(0===n.length)return this;n=n.map((function(t){return e.normalizeUnit(t)}));for(var i,o,s={},u={},a=this.toObject(),l=Dn(ho);!(o=l()).done;){var c=o.value;if(n.indexOf(c)>=0){i=c;var f=0;for(var d in u)f+=this.matrix[d][c]*u[d],u[d]=0;or(a[c])&&(f+=a[c]);var h=Math.trunc(f);for(var m in s[c]=h,u[c]=(1e3*f-1e3*h)/1e3,a)ho.indexOf(m)>ho.indexOf(c)&&vo(this.matrix,a,m,s,c)}else or(a[c])&&(u[c]=a[c])}for(var y in u)0!==u[y]&&(s[i]+=y===i?u[y]:u[y]/this.matrix[i][y]);return yo(this,{values:s},!0).normalize()},t.negate=function(){if(!this.isValid)return this;for(var e={},t=0,n=Object.keys(this.values);t<n.length;t++){var r=n[t];e[r]=0===this.values[r]?0:-this.values[r]}return yo(this,{values:e},!0)},t.equals=function(e){if(!this.isValid||!e.isValid)return!1;if(!this.loc.equals(e.loc))return!1;for(var t,n=Dn(ho);!(t=n()).done;){var r=t.value;if(i=this.values[r],o=e.values[r],!(void 0===i||0===i?void 0===o||0===o:i===o))return!1}var i,o;return!0},pn(e,[{key:"locale",get:function(){return this.isValid?this.loc.locale:null}},{key:"numberingSystem",get:function(){return this.isValid?this.loc.numberingSystem:null}},{key:"years",get:function(){return this.isValid?this.values.years||0:NaN}},{key:"quarters",get:function(){return this.isValid?this.values.quarters||0:NaN}},{key:"months",get:function(){return this.isValid?this.values.months||0:NaN}},{key:"weeks",get:function(){return this.isValid?this.values.weeks||0:NaN}},{key:"days",get:function(){return this.isValid?this.values.days||0:NaN}},{key:"hours",get:function(){return this.isValid?this.values.hours||0:NaN}},{key:"minutes",get:function(){return this.isValid?this.values.minutes||0:NaN}},{key:"seconds",get:function(){return this.isValid?this.values.seconds||0:NaN}},{key:"milliseconds",get:function(){return this.isValid?this.values.milliseconds||0:NaN}},{key:"isValid",get:function(){return null===this.invalid}},{key:"invalidReason",get:function(){return this.invalid?this.invalid.reason:null}},{key:"invalidExplanation",get:function(){return this.invalid?this.invalid.explanation:null}}]),e}();var go=function(){function e(e){this.s=e.start,this.e=e.end,this.invalid=e.invalid||null,this.isLuxonInterval=!0}e.invalid=function(t,n){if(void 0===n&&(n=null),!t)throw new Fn("need to specify a reason the Interval is invalid");var r=t instanceof Hr?t:new Hr(t,n);if(li.throwOnInvalid)throw new _n(r);return new e({invalid:r})},e.fromDateTimes=function(t,n){var r=gs(t),i=gs(n),o=function(e,t){return e&&e.isValid?t&&t.isValid?t<e?go.invalid("end before start","The end of an interval must be after its start, but you had start="+e.toISO()+" and end="+t.toISO()):null:go.invalid("missing or invalid end"):go.invalid("missing or invalid start")}(r,i);return null==o?new e({start:r,end:i}):o},e.after=function(t,n){var r=po.fromDurationLike(n),i=gs(t);return e.fromDateTimes(i,i.plus(r))},e.before=function(t,n){var r=po.fromDurationLike(n),i=gs(t);return e.fromDateTimes(i.minus(r),i)},e.fromISO=function(t,n){var r=(t||"").split("/",2),i=r[0],o=r[1];if(i&&o){var s,u,a,l;try{u=(s=ps.fromISO(i,n)).isValid}catch(e){u=!1}try{l=(a=ps.fromISO(o,n)).isValid}catch(e){l=!1}if(u&&l)return e.fromDateTimes(s,a);if(u){var c=po.fromISO(o,n);if(c.isValid)return e.after(s,c)}else if(l){var f=po.fromISO(i,n);if(f.isValid)return e.before(a,f)}}return e.invalid("unparsable",'the input "'+t+"\" can't be parsed as ISO 8601")},e.isInterval=function(e){return e&&e.isLuxonInterval||!1};var t=e.prototype;return t.length=function(e){return void 0===e&&(e="milliseconds"),this.isValid?this.toDuration.apply(this,[e]).get(e):NaN},t.count=function(e){if(void 0===e&&(e="milliseconds"),!this.isValid)return NaN;var t=this.start.startOf(e),n=this.end.startOf(e);return Math.floor(n.diff(t,e).get(e))+1},t.hasSame=function(e){return!!this.isValid&&(this.isEmpty()||this.e.minus(1).hasSame(this.s,e))},t.isEmpty=function(){return this.s.valueOf()===this.e.valueOf()},t.isAfter=function(e){return!!this.isValid&&this.s>e},t.isBefore=function(e){return!!this.isValid&&this.e<=e},t.contains=function(e){return!!this.isValid&&(this.s<=e&&this.e>e)},t.set=function(t){var n=void 0===t?{}:t,r=n.start,i=n.end;return this.isValid?e.fromDateTimes(r||this.s,i||this.e):this},t.splitAt=function(){var t=this;if(!this.isValid)return[];for(var n=arguments.length,r=new Array(n),i=0;i<n;i++)r[i]=arguments[i];for(var o=r.map(gs).filter((function(e){return t.contains(e)})).sort(),s=[],u=this.s,a=0;u<this.e;){var l=o[a]||this.e,c=+l>+this.e?this.e:l;s.push(e.fromDateTimes(u,c)),u=c,a+=1}return s},t.splitBy=function(t){var n=po.fromDurationLike(t);if(!this.isValid||!n.isValid||0===n.as("milliseconds"))return[];for(var r,i=this.s,o=1,s=[];i<this.e;){var u=this.start.plus(n.mapUnits((function(e){return e*o})));r=+u>+this.e?this.e:u,s.push(e.fromDateTimes(i,r)),i=r,o+=1}return s},t.divideEqually=function(e){return this.isValid?this.splitBy(this.length()/e).slice(0,e):[]},t.overlaps=function(e){return this.e>e.s&&this.s<e.e},t.abutsStart=function(e){return!!this.isValid&&+this.e==+e.s},t.abutsEnd=function(e){return!!this.isValid&&+e.e==+this.s},t.engulfs=function(e){return!!this.isValid&&(this.s<=e.s&&this.e>=e.e)},t.equals=function(e){return!(!this.isValid||!e.isValid)&&(this.s.equals(e.s)&&this.e.equals(e.e))},t.intersection=function(t){if(!this.isValid)return this;var n=this.s>t.s?this.s:t.s,r=this.e<t.e?this.e:t.e;return n>=r?null:e.fromDateTimes(n,r)},t.union=function(t){if(!this.isValid)return this;var n=this.s<t.s?this.s:t.s,r=this.e>t.e?this.e:t.e;return e.fromDateTimes(n,r)},e.merge=function(e){var t=e.sort((function(e,t){return e.s-t.s})).reduce((function(e,t){var n=e[0],r=e[1];return r?r.overlaps(t)||r.abutsStart(t)?[n,r.union(t)]:[n.concat([r]),t]:[n,t]}),[[],null]),n=t[0],r=t[1];return r&&n.push(r),n},e.xor=function(t){for(var n,r,i=null,o=0,s=[],u=t.map((function(e){return[{time:e.s,type:"s"},{time:e.e,type:"e"}]})),a=Dn((n=Array.prototype).concat.apply(n,u).sort((function(e,t){return e.time-t.time})));!(r=a()).done;){var l=r.value;1===(o+="s"===l.type?1:-1)?i=l.time:(i&&+i!=+l.time&&s.push(e.fromDateTimes(i,l.time)),i=null)}return e.merge(s)},t.difference=function(){for(var t=this,n=arguments.length,r=new Array(n),i=0;i<n;i++)r[i]=arguments[i];return e.xor([this].concat(r)).map((function(e){return t.intersection(e)})).filter((function(e){return e&&!e.isEmpty()}))},t.toString=function(){return this.isValid?"["+this.s.toISO()+" – "+this.e.toISO()+")":"Invalid Interval"},t.toISO=function(e){return this.isValid?this.s.toISO(e)+"/"+this.e.toISO(e):"Invalid Interval"},t.toISODate=function(){return this.isValid?this.s.toISODate()+"/"+this.e.toISODate():"Invalid Interval"},t.toISOTime=function(e){return this.isValid?this.s.toISOTime(e)+"/"+this.e.toISOTime(e):"Invalid Interval"},t.toFormat=function(e,t){var n=(void 0===t?{}:t).separator,r=void 0===n?" – ":n;return this.isValid?""+this.s.toFormat(e)+r+this.e.toFormat(e):"Invalid Interval"},t.toDuration=function(e,t){return this.isValid?this.e.diff(this.s,e,t):po.invalid(this.invalidReason)},t.mapEndpoints=function(t){return e.fromDateTimes(t(this.s),t(this.e))},pn(e,[{key:"start",get:function(){return this.isValid?this.s:null}},{key:"end",get:function(){return this.isValid?this.e:null}},{key:"isValid",get:function(){return null===this.invalidReason}},{key:"invalidReason",get:function(){return this.invalid?this.invalid.reason:null}},{key:"invalidExplanation",get:function(){return this.invalid?this.invalid.explanation:null}}]),e}(),wo=function(){function e(){}return e.hasDST=function(e){void 0===e&&(e=li.defaultZone);var t=ps.now().setZone(e).set({month:12});return!e.isUniversal&&t.offset!==t.set({month:6}).offset},e.isValidIANAZone=function(e){return Kr.isValidZone(e)},e.normalizeZone=function(e){return ni(e,li.defaultZone)},e.months=function(e,t){void 0===e&&(e="long");var n=void 0===t?{}:t,r=n.locale,i=void 0===r?null:r,o=n.numberingSystem,s=void 0===o?null:o,u=n.locObj,a=void 0===u?null:u,l=n.outputCalendar,c=void 0===l?"gregory":l;return(a||xi.create(i,s,c)).months(e)},e.monthsFormat=function(e,t){void 0===e&&(e="long");var n=void 0===t?{}:t,r=n.locale,i=void 0===r?null:r,o=n.numberingSystem,s=void 0===o?null:o,u=n.locObj,a=void 0===u?null:u,l=n.outputCalendar,c=void 0===l?"gregory":l;return(a||xi.create(i,s,c)).months(e,!0)},e.weekdays=function(e,t){void 0===e&&(e="long");var n=void 0===t?{}:t,r=n.locale,i=void 0===r?null:r,o=n.numberingSystem,s=void 0===o?null:o,u=n.locObj;return((void 0===u?null:u)||xi.create(i,s,null)).weekdays(e)},e.weekdaysFormat=function(e,t){void 0===e&&(e="long");var n=void 0===t?{}:t,r=n.locale,i=void 0===r?null:r,o=n.numberingSystem,s=void 0===o?null:o,u=n.locObj;return((void 0===u?null:u)||xi.create(i,s,null)).weekdays(e,!0)},e.meridiems=function(e){var t=(void 0===e?{}:e).locale,n=void 0===t?null:t;return xi.create(n).meridiems()},e.eras=function(e,t){void 0===e&&(e="short");var n=(void 0===t?{}:t).locale,r=void 0===n?null:n;return xi.create(r,null,"gregory").eras(e)},e.features=function(){return{relative:ur()}},e}();function ko(e,t){var n=function(e){return e.toUTC(0,{keepLocalTime:!0}).startOf("day").valueOf()},r=n(t)-n(e);return Math.floor(po.fromMillis(r).as("days"))}function bo(e,t,n,r){var i=function(e,t,n){for(var r,i,o={},s=0,u=[["years",function(e,t){return t.year-e.year}],["quarters",function(e,t){return t.quarter-e.quarter}],["months",function(e,t){return t.month-e.month+12*(t.year-e.year)}],["weeks",function(e,t){var n=ko(e,t);return(n-n%7)/7}],["days",ko]];s<u.length;s++){var a=u[s],l=a[0],c=a[1];if(n.indexOf(l)>=0){var f;r=l;var d,h=c(e,t);(i=e.plus(((f={})[l]=h,f)))>t?(e=e.plus(((d={})[l]=h-1,d)),h-=1):e=i,o[l]=h}}return[e,o,i,r]}(e,t,n),o=i[0],s=i[1],u=i[2],a=i[3],l=t-o,c=n.filter((function(e){return["hours","minutes","seconds","milliseconds"].indexOf(e)>=0}));if(0===c.length){var f;if(u<t)u=o.plus(((f={})[a]=1,f));u!==o&&(s[a]=(s[a]||0)+l/(u-o))}var d,h=po.fromObject(s,r);return c.length>0?(d=po.fromMillis(l,r)).shiftTo.apply(d,c).plus(h):h}var xo={arab:"[٠-٩]",arabext:"[۰-۹]",bali:"[᭐-᭙]",beng:"[০-৯]",deva:"[०-९]",fullwide:"[0-9]",gujr:"[૦-૯]",hanidec:"[〇|一|二|三|四|五|六|七|八|九]",khmr:"[០-៩]",knda:"[೦-೯]",laoo:"[໐-໙]",limb:"[᥆-᥏]",mlym:"[൦-൯]",mong:"[᠐-᠙]",mymr:"[၀-၉]",orya:"[୦-୯]",tamldec:"[௦-௯]",telu:"[౦-౯]",thai:"[๐-๙]",tibt:"[༠-༩]",latn:"\\d"},So={arab:[1632,1641],arabext:[1776,1785],bali:[6992,7001],beng:[2534,2543],deva:[2406,2415],fullwide:[65296,65303],gujr:[2790,2799],khmr:[6112,6121],knda:[3302,3311],laoo:[3792,3801],limb:[6470,6479],mlym:[3430,3439],mong:[6160,6169],mymr:[4160,4169],orya:[2918,2927],tamldec:[3046,3055],telu:[3174,3183],thai:[3664,3673],tibt:[3872,3881]},To=xo.hanidec.replace(/[\[|\]]/g,"").split("");function Mo(e,t){var n=e.numberingSystem;return void 0===t&&(t=""),new RegExp(""+xo[n||"latn"]+t)}function Oo(e,t){return void 0===t&&(t=function(e){return e}),{regex:e,deser:function(e){var n=e[0];return t(function(e){var t=parseInt(e,10);if(isNaN(t)){t="";for(var n=0;n<e.length;n++){var r=e.charCodeAt(n);if(-1!==e[n].search(xo.hanidec))t+=To.indexOf(e[n]);else for(var i in So){var o=So[i],s=o[0],u=o[1];r>=s&&r<=u&&(t+=r-s)}}return parseInt(t,10)}return t}(n))}}}var Do="[ "+String.fromCharCode(160)+"]",No=new RegExp(Do,"g");function Eo(e){return e.replace(/\./g,"\\.?").replace(No,Do)}function _o(e){return e.replace(/\./g,"").replace(No," ").toLowerCase()}function Io(e,t){return null===e?null:{regex:RegExp(e.map(Eo).join("|")),deser:function(n){var r=n[0];return e.findIndex((function(e){return _o(r)===_o(e)}))+t}}}function Vo(e,t){return{regex:e,deser:function(e){return Sr(e[1],e[2])},groups:t}}function Co(e){return{regex:e,deser:function(e){return e[0]}}}var Fo={year:{"2-digit":"yy",numeric:"yyyyy"},month:{numeric:"M","2-digit":"MM",short:"MMM",long:"MMMM"},day:{numeric:"d","2-digit":"dd"},weekday:{short:"EEE",long:"EEEE"},dayperiod:"a",dayPeriod:"a",hour:{numeric:"h","2-digit":"hh"},minute:{numeric:"m","2-digit":"mm"},second:{numeric:"s","2-digit":"ss"}};var zo=null;function Ao(e,t){if(e.literal)return e;var n=Ur.macroTokenToFormatOpts(e.val);if(!n)return e;var r=Ur.create(t,n).formatDateTimeParts((zo||(zo=ps.fromMillis(1555555555555)),zo)).map((function(e){return function(e,t,n){var r=e.type,i=e.value;if("literal"===r)return{literal:!0,val:i};var o=n[r],s=Fo[r];return"object"==typeof s&&(s=s[o]),s?{literal:!1,val:s}:void 0}(e,0,n)}));return r.includes(void 0)?e:r}function Lo(e,t,n){var r=function(e,t){var n;return(n=Array.prototype).concat.apply(n,e.map((function(e){return Ao(e,t)})))}(Ur.parseFormat(n),e),i=r.map((function(t){return n=t,i=Mo(r=e),o=Mo(r,"{2}"),s=Mo(r,"{3}"),u=Mo(r,"{4}"),a=Mo(r,"{6}"),l=Mo(r,"{1,2}"),c=Mo(r,"{1,3}"),f=Mo(r,"{1,6}"),d=Mo(r,"{1,9}"),h=Mo(r,"{2,4}"),m=Mo(r,"{4,6}"),y=function(e){return{regex:RegExp((t=e.val,t.replace(/[\-\[\]{}()*+?.,\\\^$|#\s]/g,"\\$&"))),deser:function(e){return e[0]},literal:!0};var t},v=function(e){if(n.literal)return y(e);switch(e.val){case"G":return Io(r.eras("short",!1),0);case"GG":return Io(r.eras("long",!1),0);case"y":return Oo(f);case"yy":case"kk":return Oo(h,br);case"yyyy":case"kkkk":return Oo(u);case"yyyyy":return Oo(m);case"yyyyyy":return Oo(a);case"M":case"L":case"d":case"H":case"h":case"m":case"q":case"s":case"W":return Oo(l);case"MM":case"LL":case"dd":case"HH":case"hh":case"mm":case"qq":case"ss":case"WW":return Oo(o);case"MMM":return Io(r.months("short",!0,!1),1);case"MMMM":return Io(r.months("long",!0,!1),1);case"LLL":return Io(r.months("short",!1,!1),1);case"LLLL":return Io(r.months("long",!1,!1),1);case"o":case"S":return Oo(c);case"ooo":case"SSS":return Oo(s);case"u":return Co(d);case"uu":return Co(l);case"uuu":case"E":case"c":return Oo(i);case"a":return Io(r.meridiems(),0);case"EEE":return Io(r.weekdays("short",!1,!1),1);case"EEEE":return Io(r.weekdays("long",!1,!1),1);case"ccc":return Io(r.weekdays("short",!0,!1),1);case"cccc":return Io(r.weekdays("long",!0,!1),1);case"Z":case"ZZ":return Vo(new 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e=JSON.parse(this.responseText).intradayPricing,t=0,n=yn.DateTime.now();e.length>0&&(t=parseFloat(e[e.length-1].price).toFixed(2),n=yn.DateTime.fromISO(e[e.length-1].time));document.getElementById("md-current-price").innerHTML="$"+t;document.getElementById("md-current-time").innerHTML=n.toLocaleString(yn.DateTime.DATETIME_FULL);const r=[],i=[];e.forEach((e=>{const{price:t,time:n}=e,o=yn.DateTime.fromISO(n),s=parseFloat(t).toFixed(2);r.push(o.toUnixInteger()),i.push(s)}));const o=document.getElementById("md-intraday-chart"),s=new mn({width:300,height:120,class:"spark",pxAlign:!1,cursor:{show:!1},select:{show:!1},legend:{show:!1},scales:{x:{time:!1}},axes:[{show:!1},{show:!1}],series:[{},{stroke:"#ec5b2e",fill:"#ffb39c"}]},[r,i]).ctx.canvas;o.parentNode.append(s)}},ws.open("GET","https://medtech100.com/md100/json/pricing",!0),ws.send(); //# sourceMappingURL=index.80f28a61.js.map </script> </head> <body> <div id="md-tech-ad"> <table class="md-table" align="center" cellpadding="0" cellspacing="0" width="100%"> <tr> <td width="100%"> <div class="md-align"> <img id="md-logo" class="md-margin" src="https://images.designworldonline.com/newsletters/images/ee034d8d8274c1ee5e8111f11cf1be49.png" alt="Medtech 100 logo"> </div> </td> </tr> <tr> <td width="100%"> <div class="md-align"> <div class="margin-text"> <span style="font-weight:600;color:#e06636!important;font-size:16px!important;line-height:14px!important"> Market Summary > Current Price </span> </div> </div> </td> </tr> <tr> <td width="100%"> <div class="md-align" id="md-content-container"> <div id="md-current-price"></div> <div id="md-current-time"></div> <div id="md-chart-container"> <div id="md-intraday-chart"></div> </div> </div> </td> </tr> <tr> <td width="100%"> <div class="md-align"> <div class="md-margin-text"> <span style="font-size:13px;line-height:15px!important"> The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing. </span> </div> </div> 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