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Barthel Lab – A Lab of Glycobiological Inquiry and Therapeutics for Cancer and Immune Diseases
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background-image: none; border-top-width: 0px; border-top-color: #03a9f4; border-top-style: solid; border-right-width: 0px; border-right-color: #03a9f4; border-right-style: solid; border-bottom-width: 0px; border-bottom-color: #03a9f4; border-bottom-style: solid; border-left-width: 0px; border-left-color: #03a9f4; border-left-style: solid; } #colibri .woocommerce-store-notice:hover,#colibri .woocommerce-store-notice:focus,#colibri .woocommerce-store-notice:active,#colibri.woocommerce .content .h-section input[type=submit]:hover,#colibri.woocommerce .content .h-section input[type=submit]:focus,#colibri.woocommerce .content .h-section input[type=submit]:active,#colibri.woocommerce-page .content .h-section input[type=button]:hover,#colibri.woocommerce-page .content .h-section input[type=button]:focus,#colibri.woocommerce-page .content .h-section input[type=button]:active,#colibri.woocommerce .content .h-section input[type=button]:hover,#colibri.woocommerce .content .h-section input[type=button]:focus,#colibri.woocommerce .content .h-section input[type=button]:active,#colibri.woocommerce-page .content .h-section .button:hover,#colibri.woocommerce-page .content .h-section .button:focus,#colibri.woocommerce-page .content .h-section .button:active,#colibri.woocommerce .content .h-section .button:hover,#colibri.woocommerce .content .h-section .button:focus,#colibri.woocommerce .content .h-section .button:active,#colibri.woocommerce-page .content .h-section a.button:hover,#colibri.woocommerce-page .content .h-section a.button:focus,#colibri.woocommerce-page .content .h-section a.button:active,#colibri.woocommerce .content .h-section a.button:hover,#colibri.woocommerce .content .h-section a.button:focus,#colibri.woocommerce .content .h-section a.button:active,#colibri.woocommerce-page .content .h-section button.button:hover,#colibri.woocommerce-page .content .h-section button.button:focus,#colibri.woocommerce-page .content .h-section button.button:active,#colibri.woocommerce .content .h-section button.button:hover,#colibri.woocommerce .content .h-section button.button:focus,#colibri.woocommerce .content .h-section button.button:active,#colibri.woocommerce-page .content .h-section input.button:hover,#colibri.woocommerce-page .content .h-section input.button:focus,#colibri.woocommerce-page .content .h-section input.button:active,#colibri.woocommerce .content .h-section input.button:hover,#colibri.woocommerce .content .h-section input.button:focus,#colibri.woocommerce .content .h-section input.button:active,#colibri.woocommerce-page .content .h-section input#submit:hover,#colibri.woocommerce-page .content .h-section input#submit:focus,#colibri.woocommerce-page .content .h-section input#submit:active,#colibri.woocommerce .content .h-section input#submit:hover,#colibri.woocommerce .content .h-section input#submit:focus,#colibri.woocommerce .content .h-section input#submit:active,#colibri.woocommerce-page .content .h-section a.added_to_cart:hover,#colibri.woocommerce-page .content .h-section a.added_to_cart:focus,#colibri.woocommerce-page .content .h-section a.added_to_cart:active,#colibri.woocommerce .content .h-section a.added_to_cart:hover,#colibri.woocommerce .content .h-section a.added_to_cart:focus,#colibri.woocommerce .content .h-section a.added_to_cart:active,#colibri.woocommerce-page .content .h-section .ui-slider-range:hover,#colibri.woocommerce-page .content .h-section .ui-slider-range:focus,#colibri.woocommerce-page .content .h-section .ui-slider-range:active,#colibri.woocommerce .content .h-section .ui-slider-range:hover,#colibri.woocommerce .content .h-section .ui-slider-range:focus,#colibri.woocommerce .content .h-section .ui-slider-range:active,#colibri.woocommerce-page .content .h-section .ui-slider-handle:hover,#colibri.woocommerce-page .content .h-section .ui-slider-handle:focus,#colibri.woocommerce-page .content .h-section .ui-slider-handle:active,#colibri.woocommerce .content .h-section .ui-slider-handle:hover,#colibri.woocommerce .content .h-section .ui-slider-handle:focus,#colibri.woocommerce .content .h-section .ui-slider-handle:active { background-color: rgb(2, 110, 159); background-image: none; border-top-width: 0px; border-top-color: rgb(2, 110, 159); border-top-style: solid; border-right-width: 0px; border-right-color: rgb(2, 110, 159); border-right-style: solid; border-bottom-width: 0px; border-bottom-color: rgb(2, 110, 159); border-bottom-style: solid; border-left-width: 0px; border-left-color: rgb(2, 110, 159); border-left-style: solid; } #colibri.woocommerce-page .content .h-section .star-rating::before,#colibri.woocommerce .content .h-section .star-rating::before,#colibri.woocommerce-page .content .h-section .star-rating span::before,#colibri.woocommerce .content .h-section .star-rating span::before { color: #03a9f4; } #colibri.woocommerce-page .content .h-section .price,#colibri.woocommerce .content .h-section .price { color: #03a9f4; } #colibri.woocommerce-page .content .h-section .price del,#colibri.woocommerce .content .h-section .price del { color: rgb(84, 194, 244); } #colibri.woocommerce-page .content .h-section .onsale,#colibri.woocommerce .content .h-section .onsale { background-color: #03a9f4; background-image: none; } #colibri.woocommerce-page .content .h-section .onsale:hover,#colibri.woocommerce-page .content .h-section .onsale:focus,#colibri.woocommerce-page .content .h-section .onsale:active,#colibri.woocommerce .content .h-section .onsale:hover,#colibri.woocommerce .content .h-section .onsale:focus,#colibri.woocommerce .content .h-section .onsale:active { background-color: rgb(2, 110, 159); background-image: none; } #colibri.woocommerce ul.products li.product h2:hover { color: #03a9f4; } #colibri.woocommerce-page .content .h-section .woocommerce-pagination .page-numbers.current,#colibri.woocommerce .content .h-section .woocommerce-pagination .page-numbers.current,#colibri.woocommerce-page .content .h-section .woocommerce-pagination a.page-numbers:hover,#colibri.woocommerce .content .h-section .woocommerce-pagination a.page-numbers:hover { background-color: #03a9f4; background-image: none; } #colibri.woocommerce-page .content .h-section .comment-form-rating .stars a,#colibri.woocommerce .content .h-section .comment-form-rating .stars a { color: #03a9f4; } .h-section-global-spacing { padding-top: 90px; padding-bottom: 90px; } #colibri .colibri-language-switcher { background-color: white; background-image: none; top: 80px; border-top-width: 0px; border-top-style: none; border-top-left-radius: 4px; border-top-right-radius: 0px; border-right-width: 0px; border-right-style: none; border-bottom-width: 0px; border-bottom-style: none; border-bottom-left-radius: 4px; border-bottom-right-radius: 0px; border-left-width: 0px; border-left-style: none; } #colibri .colibri-language-switcher .lang-item { padding-top: 14px; padding-right: 18px; padding-bottom: 14px; padding-left: 18px; } body { font-family: Open Sans; font-weight: 400; font-size: 16px; line-height: 1.6; color: rgb(70, 112, 127); } body a { font-family: Open Sans; font-weight: 400; text-decoration: none; font-size: 1em; line-height: 1.5; color: #03a9f4; } body p { margin-bottom: 16px; font-family: Open Sans; font-weight: 400; font-size: 16px; line-height: 1.6; color: rgb(70, 112, 127); } body .h-lead p { margin-bottom: 16px; font-family: Open Sans; font-weight: 300; font-size: 1.25em; line-height: 1.5; color: rgb(37, 41, 42); } body blockquote p { margin-bottom: 16px; font-family: Open Sans; font-weight: 400; font-size: 16px; line-height: 1.6; color: rgb(70, 112, 127); } body h1 { margin-bottom: 16px; font-family: Open Sans; font-weight: 300; font-size: 3.375em; line-height: 1.26; color: rgb(23, 37, 42); } body h2 { margin-bottom: 16px; font-family: Open Sans; font-weight: 300; font-size: 2.625em; line-height: 1.143; color: rgb(23, 37, 42); } body h3 { margin-bottom: 16px; font-family: Open Sans; font-weight: 300; font-size: 2.25em; line-height: 1.25; color: rgb(23, 37, 42); } body h4 { margin-bottom: 16px; font-family: Open Sans; font-weight: 600; font-size: 1.25em; line-height: 1.6; color: rgb(23, 37, 42); } body h5 { margin-bottom: 16px; font-family: Open Sans; font-weight: 600; font-size: 1.125em; line-height: 1.55; color: rgb(23, 37, 42); } body h6 { margin-bottom: 16px; font-family: Open Sans; font-weight: 600; font-size: 1em; line-height: 1.6; color: rgb(23, 37, 42); } @media (min-width: 768px) and (max-width: 1023px){ .h-section-global-spacing { padding-top: 60px; padding-bottom: 60px; } } @media (max-width: 767px){ .h-section-global-spacing { padding-top: 30px; padding-bottom: 30px; } } /* part css : page */ #colibri .style-217 { height: auto; min-height: unset; background-color: #FFFFFF; background-image: none; padding-top: 45px; padding-bottom: 45px; } #colibri .style-219 { text-align: center; height: auto; min-height: unset; padding-top: 0px; padding-right: 30px; padding-bottom: 0px; padding-left: 30px; } #colibri .style-220-image { opacity: 1; box-shadow: 0px 10px 20px 2px rgba(0, 0, 0, 0.2) ; } #colibri .style-220-caption { margin-top: 10px; } #colibri .style-220-frameImage { z-index: -1; transform: translateX(5%) translateY(5%); transform-origin: center center 0px; background-color: #03a9f4; height: 100%; width: 100% ; border-top-width: 10px; border-top-color: #03a9f4; border-top-style: none; border-right-width: 10px; border-right-color: #03a9f4; border-right-style: none; border-bottom-width: 10px; border-bottom-color: #03a9f4; border-bottom-style: none; border-left-width: 10px; border-left-color: #03a9f4; border-left-style: none; } #colibri .style-221 { text-align: left; height: auto; min-height: unset; } #colibri .style-222 .text-wrapper-fancy svg path { stroke: #000000; stroke-linejoin: initial; stroke-linecap: initial; stroke-width: 8px; } #colibri .style-233 { height: auto; min-height: unset; background-color: rgb(245, 250, 253); background-image: none; padding-top: 45px; padding-bottom: 45px; } #colibri .style-235 { text-align: left; height: auto; min-height: unset; } #colibri .style-237 ol { list-style-type: decimal; } #colibri .style-237 ul { list-style-type: disc; } #colibri .style-243 { text-align: center; height: auto; min-height: unset; padding-top: 0px; padding-right: 30px; padding-bottom: 0px; padding-left: 30px; } #colibri .style-244-image { opacity: 1; box-shadow: 0px 10px 20px 2px rgba(0, 0, 0, 0.2) ; } #colibri .style-244-caption { margin-top: 10px; } #colibri .style-244-frameImage { z-index: -1; transform: translateX(-5%) translateY(5%); transform-origin: center center 0px; background-color: #03a9f4; height: 100%; width: 100% ; border-top-width: 10px; border-top-color: #03a9f4; border-top-style: none; border-right-width: 10px; border-right-color: #03a9f4; border-right-style: none; border-bottom-width: 10px; border-bottom-color: #03a9f4; border-bottom-style: none; border-left-width: 10px; border-left-color: #03a9f4; border-left-style: none; } #colibri .style-349 { height: auto; min-height: unset; background-position: center center; background-size: cover; background-image: linear-gradient(90deg, rgba(106, 17, 203, 0.8) 0%, rgba(37, 117, 252, 0.8) 100%); background-attachment: scroll; background-repeat: no-repeat; padding-top: 40px; padding-bottom: 40px; color: #FFFFFF; } #colibri .style-349 h1 { color: #FFFFFF; } #colibri .style-349 h2 { color: #FFFFFF; } #colibri .style-349 h3 { color: #FFFFFF; } #colibri .style-349 h4 { color: #FFFFFF; } #colibri .style-349 h5 { color: #FFFFFF; } #colibri .style-349 h6 { color: #FFFFFF; } #colibri .style-349 p { color: #FFFFFF; } #colibri .style-353 { text-align: center; height: auto; min-height: unset; } #colibri .style-355-icon { width: 14px; height: 14px; margin-right: 10px; margin-left: 0px; } #colibri .style-355 { padding-top: 15px; padding-right: 30px; padding-bottom: 15px; padding-left: 30px; font-family: Open Sans; font-weight: 600; text-transform: uppercase; font-size: 14px; line-height: 1; letter-spacing: 1px; color: #fff; background-color: #f79007; background-image: none; border-top-width: 2px; border-top-color: #f79007; border-top-style: solid; border-top-left-radius: 5px; border-top-right-radius: 5px; border-right-width: 2px; border-right-color: #f79007; border-right-style: solid; border-bottom-width: 2px; border-bottom-color: #f79007; border-bottom-style: solid; border-bottom-left-radius: 5px; border-bottom-right-radius: 5px; border-left-width: 2px; border-left-color: #f79007; border-left-style: solid; text-align: center; } #colibri .style-355:hover,#colibri .style-355:focus { background-color: rgb(247, 179, 89); border-top-color: rgb(247, 179, 89); border-right-color: rgb(247, 179, 89); border-bottom-color: rgb(247, 179, 89); border-left-color: rgb(247, 179, 89); } #colibri .style-355:active .style-355-icon { width: 14px; height: 14px; margin-right: 10px; margin-left: 0px; } #colibri .style-367 { line-height: 0.7; } #colibri .style-367 p { line-height: 0.7; } #colibri .style-367 ol { list-style-type: decimal; } #colibri .style-367 ul { list-style-type: disc; } #colibri .style-local-246-c4-outer { width: 39.98% ; flex: 0 0 auto; -ms-flex: 0 0 auto; } #colibri .style-local-246-c6-outer { width: 60.02% ; flex: 0 0 auto; -ms-flex: 0 0 auto; } #colibri .style-local-246-c15-outer { width: 53.14% ; flex: 0 0 auto; -ms-flex: 0 0 auto; } #colibri .style-local-246-c17-outer { width: 46.86% ; flex: 0 0 auto; -ms-flex: 0 0 auto; } #colibri .style-2 { animation-duration: 0.5s; padding-top: 20px; padding-bottom: 20px; } #colibri .h-navigation_sticky .style-2,#colibri .h-navigation_sticky.style-2 { background-color: #ffffff; background-image: none; padding-top: 10px; padding-bottom: 10px; box-shadow: 0px 0px 4px 0px rgba(0,0,0,0.5) ; } #colibri .style-4 { text-align: center; height: auto; min-height: unset; } #colibri .style-5-image { max-height: 70px; } #colibri .style-5 a,#colibri .style-5 .logo-text { color: #ffffff; text-decoration: none; } #colibri .h-navigation_sticky .style-5-image,#colibri .h-navigation_sticky.style-5-image { max-height: 70px; } #colibri .h-navigation_sticky .style-5 a,#colibri .h-navigation_sticky .style-5 .logo-text,#colibri .h-navigation_sticky.style-5 a,#colibri .h-navigation_sticky.style-5 .logo-text { color: #000000; text-decoration: none; } #colibri .style-6 { text-align: center; height: auto; min-height: unset; } #colibri .style-7 { height: 50px; } #colibri .style-8 { text-align: center; height: auto; min-height: unset; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu { justify-content: flex-end; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li { margin-top: 0px; margin-right: 20px; margin-bottom: 0px; margin-left: 20px; padding-top: 10px; padding-right: 0px; padding-bottom: 10px; padding-left: 0px; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li.current_page_item,#colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li.current_page_item:hover { margin-top: 0px; margin-right: 20px; margin-bottom: 0px; margin-left: 20px; padding-top: 10px; padding-right: 0px; padding-bottom: 10px; padding-left: 0px; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li > a { font-family: Open Sans; font-weight: 600; text-transform: uppercase; font-size: 14px; line-height: 1.5em; letter-spacing: 0px; color: #FFFFFF; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li.hover > a { color: rgb(166, 220, 244); } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li:hover > a,#colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li.hover > a { color: rgb(166, 220, 244); } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li.current_page_item > a,#colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li.current_page_item > a:hover { font-family: Open Sans; font-weight: 600; text-transform: uppercase; font-size: 14px; line-height: 1.5em; letter-spacing: 0px; color: rgb(166, 220, 244); } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul { background-color: #ffffff; background-image: none; margin-right: 5px; margin-left: 5px; box-shadow: 0px 0px 5px 2px rgba(0, 0, 0, 0.04) ; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul li { padding-top: 10px; padding-right: 20px; padding-bottom: 10px; padding-left: 20px; border-top-width: 0px; border-top-style: none; border-right-width: 0px; border-right-style: none; border-bottom-width: 1px; border-bottom-color: rgba(128,128,128,.2); border-bottom-style: solid; border-left-width: 0px; border-left-style: none; background-color: rgb(255, 255, 255); background-image: none; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul > li.hover { background-color: #03a9f4; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul > li:hover,#colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul > li.hover { background-color: #03a9f4; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul li.current_page_item,#colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul > li.current_page_item:hover { padding-top: 10px; padding-right: 20px; padding-bottom: 10px; padding-left: 20px; border-top-width: 0px; border-top-style: none; border-right-width: 0px; border-right-style: none; border-bottom-width: 1px; border-bottom-color: rgba(128,128,128,.2); border-bottom-style: solid; border-left-width: 0px; border-left-style: none; background-color: #03a9f4; background-image: none; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul > li > a { font-size: 14px; color: rgb(37, 41, 42); } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul > li.hover > a { color: rgb(255, 255, 255); } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul > li:hover > a,#colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul > li.hover > a { color: rgb(255, 255, 255); } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul > li.current_page_item > a,#colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > ul > li.current_page_item > a:hover { font-size: 14px; color: rgb(255, 255, 255); } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu.bordered-active-item > li::after,#colibri .style-9 ul.colibri-menu.bordered-active-item > li::before { background-color: rgb(166, 220, 244); background-image: none; height: 3px; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu.solid-active-item > li::after,#colibri .style-9 ul.colibri-menu.solid-active-item > li::before { background-color: white; background-image: none; border-top-width: 0px; border-top-style: none; border-top-left-radius: 0%; border-top-right-radius: 0%; border-right-width: 0px; border-right-style: none; border-bottom-width: 0px; border-bottom-style: none; border-bottom-left-radius: 0%; border-bottom-right-radius: 0%; border-left-width: 0px; border-left-style: none; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li > ul { margin-top: 0px; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu > li > ul::before { height: 0px; width: 100% ; } #colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > a > svg,#colibri .style-9 > div > .colibri-menu-container > ul.colibri-menu li > a > .arrow-wrapper { padding-right: 5px; padding-left: 5px; 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src="https://barthellab.bwh.harvard.edu/wp-content/uploads/2024/07/Steven-Barthel_pic.jpg" class="wp-image-314 style-220-image style-local-246-c5-image" alt="" srcset="https://barthellab.bwh.harvard.edu/wp-content/uploads/2024/07/Steven-Barthel_pic.jpg 1500w, https://barthellab.bwh.harvard.edu/wp-content/uploads/2024/07/Steven-Barthel_pic-300x300.jpg 300w, https://barthellab.bwh.harvard.edu/wp-content/uploads/2024/07/Steven-Barthel_pic-1024x1024.jpg 1024w, https://barthellab.bwh.harvard.edu/wp-content/uploads/2024/07/Steven-Barthel_pic-150x150.jpg 150w, https://barthellab.bwh.harvard.edu/wp-content/uploads/2024/07/Steven-Barthel_pic-768x768.jpg 768w" sizes="(max-width: 1500px) 100vw, 1500px" /> <div class="h-image__frame h-image__frame_shadow h-hide-sm style-220-frameImage style-local-246-c5-frameImage"></div> </div> </div> </div> </div> </div> </div> <div class="h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-221-outer style-local-246-c6-outer"> <div data-colibri-id="246-c6" class="d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-221 style-local-246-c6 position-relative"> <!----> <!----> <div class="w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center"> <!----> <div data-colibri-id="246-c7" class="h-global-transition-all h-heading style-222 style-local-246-c7 position-relative h-element"> <!----> <div class="h-heading__outer style-222 style-local-246-c7"> <!----> <!----> <h3 class="">Steven R. Barthel, Ph.D. </h3> </div> </div> <div data-colibri-id="246-c28" class="h-text h-text-component style-367 style-local-246-c28 position-relative h-element"> <!----> <!----> <div class=""> <p><strong>Assistant Professor of Dermatology</strong></p> <p><strong>Co-Director, Program of Glyco-Immunology and Oncology (PGIO)</strong></p> <p>Harvard Medical School, Brigham and Women鈥檚 Hospital</p> <p>Cancer Immunotherapy, Immune Checkpoint Blockade, Glycobiology, Metastasis</p> <p><strong>Postdoctoral Fellowship</strong></p> <p>Brigham and Women鈥檚 Hospital, Harvard</p> <p>Cancer Glycobiology and Immune Trafficking</p> <p><strong>Ph.D., Biomolecular Chemistry</strong></p> <p>University of Wisconsin-Madison</p> <p>Integrins in Leukocyte Adhesion/Migration</p> <p><strong>B.S., Biochemistry, Molecular Genetics</strong></p> <p>The Ohio State University</p> <p> <br> </p> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div data-colibri-component="section" data-colibri-id="246-c13" id="content-2" class="h-section h-section-global-spacing d-flex align-items-lg-center align-items-md-center align-items-center style-233 style-local-246-c13 position-relative"> <!----> <!----> <div class="h-section-grid-container h-section-boxed-container"> <!----> <div data-colibri-id="246-c14" class="h-row-container gutters-row-lg-2 gutters-row-md-2 gutters-row-2 gutters-row-v-lg-2 gutters-row-v-md-2 gutters-row-v-2 style-234 style-local-246-c14 position-relative"> <!----> <div class="h-row justify-content-lg-center justify-content-md-center justify-content-center align-items-lg-stretch align-items-md-stretch align-items-stretch gutters-col-lg-2 gutters-col-md-2 gutters-col-2 gutters-col-v-lg-2 gutters-col-v-md-2 gutters-col-v-2"> <!----> <div class="h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-235-outer style-local-246-c15-outer"> <div data-colibri-id="246-c15" class="d-flex h-flex-basis h-column__inner h-px-lg-2 h-px-md-2 h-px-2 v-inner-lg-2 v-inner-md-2 v-inner-2 style-235 style-local-246-c15 position-relative"> <!----> <!----> <div class="w-100 h-y-container h-column__content h-column__v-align flex-basis-100 align-self-lg-center align-self-md-center align-self-center"> <!----> <div data-colibri-id="246-c16" class="h-text h-text-component style-237 style-local-246-c16 position-relative h-element"> <!----> <!----> <div class=""> <p>The Barthel Laboratory is led by Principal Investigator Steven R. Barthel, Ph.D., an Assistant Professor in Dermatology and Co-Director of the Program of Glyco-Immunology and Oncology (PGIO) at Harvard Medical School, Brigham and Women鈥檚 Hospital. Dr. Barthel is a Faculty Affiliate for the Harvard Stem Cell Institute (HSCI), a Member of the Melanoma Program and Invasion, Metastasis Group at Dana-Farber/Harvard Cancer Center (DFHCC), and an Investigator for the Consortium for Functional Glycomics (CFG). The lab is located on the 6th floor of the Harvard Institutes of Medicine building. Dr. Barthel received his Ph.D. from the University of Wisconsin-Madison on integrin/integrin-ligand mediated leukocyte adhesion and migration. He subsequently trained as a postdoctoral fellow in the Department of Dermatology, Harvard Skin Disease Research Center at Brigham and Women鈥檚 Hospital investigating carbohydrate and integrin-dependent adhesion, migration and metastasis of immune and cancer cells to bone and skin. His work yielded novel glycobiological and cell adhesive insight into the traffic control machinery of cancer and catalyzed pivotal leaps in deciphering metastasis. He custom-engineered innovative carbohydate binding proteins (lectins), including galectin-IgG Fc fusion molecules, to identify and study unrecognized galectin ligands on melanoma, squamous cell carcinoma (SCC) and immune cells. His new galectin-fusion biologics have become versatile probes for characterizing galectin-binding proteins and galectin pathophysiological functions on tumor and immune cells, assessing galectin antibody neutralizing or stimulatory activities, and in the identification of new biomarkers for diagnosing and staging melanoma and various cancers.</p> <p>Dr. Barthel鈥檚 interdisciplinary expertise and ongoing research in glycobiology, galectins, melanoma/skin cancer, cancer stem cells, signaling, metastasis and biomarkers underlies his overall career and research goals to (1) characterize carbohydrate mediators of cancer progression and immune diseases, (2) identify and develop therapies to treat and diagnose cancer and inflammation, and to (3) mentor/train the next-generation of researchers in cancer and immunology.</p> <p> <br> </p> </div> </div> </div> </div> </div> <div class="h-column h-column-container d-flex h-col-lg-auto h-col-md-auto h-col-auto style-243-outer 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