PDB-101: Browse: Nanotechnology

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class="pdb101-left-menu-subheader-caret"><span id="caret4" class="fa fa-caret-down"></span> </div> <div class="pdb101-left-menu-subheader-text">Structures and Structure Determination</div> </div> <div id="category4" style="display:none;"> <div onclick="location.href="/browse/biomolecular-structural-biology"" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">Biomolecular Structural Biology</div> <div class="pdb101-left-menu-item-chevron"><span id="chevron-24" class="fa fa-chevron-right fade"></span> </div> </div> <div onclick="location.href="/browse/biomolecules"" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">Biomolecules</div> <div class="pdb101-left-menu-item-chevron"><span id="chevron-23" class="fa fa-chevron-right fade"></span> </div> </div> <div onclick="location.href="/browse/integrative-hybrid-methods"" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">Integrative/Hybrid Methods</div> <div class="pdb101-left-menu-item-chevron"><span id="chevron-25" class="fa fa-chevron-right fade"></span> </div> </div> <div onclick="location.href="/browse/nobel-prizes-and-pdb-structures"" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">Nobel Prizes and PDB structures</div> <div class="pdb101-left-menu-item-chevron"><span id="chevron-28" class="fa fa-chevron-right fade"></span> </div> </div> <div onclick="location.href="/browse/pdb-data"" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">PDB Data</div> <div class="pdb101-left-menu-item-chevron"><span id="chevron-26" class="fa fa-chevron-right fade"></span> </div> </div> <div onclick="location.href="/browse/protein-structure-prediction-design-and-computed-structure-models"" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">Protein Structure Prediction, Design, and Computed Structure Models</div> <div class="pdb101-left-menu-item-chevron"><span id="chevron-39" class="fa fa-chevron-right fade"></span> </div> </div> <div onclick="location.href="/browse/visualizing-molecules"" class="pdb101-left-menu-item"> <div class="pdb101-left-menu-item-text">Visualizing Molecules</div> <div class="pdb101-left-menu-item-chevron"><span id="chevron-27" class="fa fa-chevron-right fade"></span> </div> </div> </div> </div> </div> <div class="col-sm-12 col-md-9 pdb101-page-content"> <div class="row grid-list-btns"> <div class="col-xs-12 col-sm-9"> <h1>Nanotechnology</h1> </div> <div class="col-xs-12 col-sm-3 text-right"> <div role="group" class="btn-group"> <button id="grid-btn" type="button" onclick="toggleGridList("grid")" class="btn btn-default btn-sm active"><img src='https://cdn.rcsb.org/pdb101/common/images/grid.png'>Grid</button> <button id="list-btn" type="button" onclick="toggleGridList("list")" class="btn btn-default btn-sm"><img src='https://cdn.rcsb.org/pdb101/common/images/list.png'>List</button> </div> </div> </div> <div id="section-introduction"> <p><i>building on nature</i></p> <p>Scientists are using their understanding of structural biology to design new molecules to perform custom nanoscale tasks. Structures in the PDB include many successful examples of this design, ranging from designed molecular containers to custom enzymes.</p> </div> <h3>Molecule of the Month Articles (19)</h3> <div id="molecule-of-the-month-articles"> <div class="row grid-view"> <div style="display:block;" id="motm0" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/132"><img src="https://cdn.rcsb.org/pdb101/motm/132/132-Adenovirus_adenovirus-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/132">Adenovirus</a></div> </div> <div style="display:block;" id="motm1" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/21"><img src="https://cdn.rcsb.org/pdb101/motm/21/1igt-tn.gif" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/21">Antibodies</a></div> </div> <div style="display:block;" id="motm2" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/181"><img src="https://cdn.rcsb.org/pdb101/motm/181/181-CascadeAndCRISPR_1vy8-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/181">Cascade and CRISPR</a></div> </div> <div style="display:block;" id="motm3" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/124"><img src="https://cdn.rcsb.org/pdb101/motm/124/1cvn-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/124">Concanavalin A and Circular Permutation</a></div> </div> <div style="display:none;" id="motm4" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/137"><img src="https://cdn.rcsb.org/pdb101/motm/137/137-Cytochromebc1_3h1j-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/137">Cytochrome bc1</a></div> </div> <div style="display:none;" id="motm5" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/119"><img src="https://cdn.rcsb.org/pdb101/motm/119/3gbi_composite-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/119">Designed DNA Crystal</a></div> </div> <div style="display:none;" id="motm6" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/165"><img src="https://cdn.rcsb.org/pdb101/motm/165/165-DesignedProteinCages_3vdx_4egg-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/165">Designed Protein Cages</a></div> </div> <div style="display:none;" id="motm7" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/70"><img src="https://cdn.rcsb.org/pdb101/motm/70/1qys-composite-tn.gif" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/70">Designer Proteins</a></div> </div> <div style="display:none;" id="motm8" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/261"><img src="https://cdn.rcsb.org/pdb101/motm/261/4uv3_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/261">DNA-Sequencing Nanopores</a></div> </div> <div style="display:none;" id="motm9" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/229"><img src="https://cdn.rcsb.org/pdb101/motm/229/229-Fluorescent_RNA_AptamersSpinach_fluorescent_aptamer_with_RNA_in_light_orange_and_fluorophore_in_green-4kzd_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/229">Fluorescent RNA Aptamers</a></div> </div> <div style="display:none;" id="motm10" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/174"><img src="https://cdn.rcsb.org/pdb101/motm/174/174-GFPLikeProteins_1g7k-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/174">GFP-like Proteins</a></div> </div> <div style="display:none;" id="motm11" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/42"><img src="https://cdn.rcsb.org/pdb101/motm/42/1gfl-tn.gif" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/42">Green Fluorescent Protein (GFP)</a></div> </div> <div style="display:none;" id="motm12" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/131"><img src="https://cdn.rcsb.org/pdb101/motm/131/1jva-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/131">Inteins</a></div> </div> <div style="display:none;" id="motm13" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/237"><img src="https://cdn.rcsb.org/pdb101/motm/237/237-Nanodiscs_and_HDL-6clz_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/237">Nanodiscs and HDL</a></div> </div> <div style="display:none;" id="motm14" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/290"><img src="https://cdn.rcsb.org/pdb101/motm/290/7qv7_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/290">Nanowires</a></div> </div> <div style="display:none;" id="motm15" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/232"><img src="https://cdn.rcsb.org/pdb101/motm/232/231-Proteins_and_Biominerals-1q8h_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/232">Proteins and Biominerals</a></div> </div> <div style="display:none;" id="motm16" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/222"><img src="https://cdn.rcsb.org/pdb101/motm/222/221-Proteins_and_Nanoparticles-5et3_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/222">Proteins and Nanoparticles</a></div> </div> <div style="display:none;" id="motm17" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/161"><img src="https://cdn.rcsb.org/pdb101/motm/161/161-Ricin_2aai-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/161">Ricin</a></div> </div> <div style="display:none;" id="motm18" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/motm/180"><img src="https://cdn.rcsb.org/pdb101/motm/180/180-TALEffectors_3ugm-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a> <div><a href="/motm/180">TAL Effectors</a></div> </div> <div class="col-xs-12 more-or-less"><span id="motm-caret" onclick="showMoreOrLess("motm")" class="fa fa-caret-down link-color"></span><span id="motm-more-or-less" onclick="showMoreOrLess("motm")" class="link-color">More</span></div> </div> <div style="display:none;" class="list-view"> <table class="list-view"> <tr> <td class="tn"><a href="/motm/132"><img src="https://cdn.rcsb.org/pdb101/motm/132/132-Adenovirus_adenovirus-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/132" style="font-size:16px;">Adenovirus</a> <p>Adenovirus has an icosahedral capsid with unusual cell-binding fibers</p> </td> </tr> <tr> <td class="tn"><a href="/motm/21"><img src="https://cdn.rcsb.org/pdb101/motm/21/1igt-tn.gif" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/21" style="font-size:16px;">Antibodies</a> <p>Antibodies search for foreign molecules in the blood</p> </td> </tr> <tr> <td class="tn"><a href="/motm/181"><img src="https://cdn.rcsb.org/pdb101/motm/181/181-CascadeAndCRISPR_1vy8-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/181" style="font-size:16px;">Cascade and CRISPR</a> <p>Cascade and CRISPR help bacteria remember how to fight viral infection</p> </td> </tr> <tr> <td class="tn"><a href="/motm/124"><img src="https://cdn.rcsb.org/pdb101/motm/124/1cvn-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/124" style="font-size:16px;">Concanavalin A and Circular Permutation</a> <p>For some proteins, clipped and reassembled sequences can produce the same 3D shape</p> </td> </tr> <tr> <td class="tn"><a href="/motm/137"><img src="https://cdn.rcsb.org/pdb101/motm/137/137-Cytochromebc1_3h1j-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/137" style="font-size:16px;">Cytochrome bc1</a> <p>A flow of electrons powers proton pumps in cellular respiration and photosynthesis</p> </td> </tr> <tr> <td class="tn"><a href="/motm/119"><img src="https://cdn.rcsb.org/pdb101/motm/119/3gbi_composite-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/119" style="font-size:16px;">Designed DNA Crystal</a> <p>Small pieces of DNA have been engineered to form a nanoscale lattice</p> </td> </tr> <tr> <td class="tn"><a href="/motm/165"><img src="https://cdn.rcsb.org/pdb101/motm/165/165-DesignedProteinCages_3vdx_4egg-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/165" style="font-size:16px;">Designed Protein Cages</a> <p>Researchers are modifying natural proteins to design new self-assembling protein cages</p> </td> </tr> <tr> <td class="tn"><a href="/motm/70"><img src="https://cdn.rcsb.org/pdb101/motm/70/1qys-composite-tn.gif" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/70" style="font-size:16px;">Designer Proteins</a> <p>Researchers have successfully designed entirely new proteins based on biological principles</p> </td> </tr> <tr> <td class="tn"><a href="/motm/261"><img src="https://cdn.rcsb.org/pdb101/motm/261/4uv3_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/261" style="font-size:16px;">DNA-Sequencing Nanopores</a> <p>Designer nanopores work with enzymes to offer pocket-sized DNA sequencing</p> </td> </tr> <tr> <td class="tn"><a href="/motm/229"><img src="https://cdn.rcsb.org/pdb101/motm/229/229-Fluorescent_RNA_AptamersSpinach_fluorescent_aptamer_with_RNA_in_light_orange_and_fluorophore_in_green-4kzd_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/229" style="font-size:16px;">Fluorescent RNA Aptamers</a> <p>RNA aptamers are being engineered to track molecules inside living cells</p> </td> </tr> <tr> <td class="tn"><a href="/motm/174"><img src="https://cdn.rcsb.org/pdb101/motm/174/174-GFPLikeProteins_1g7k-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/174" style="font-size:16px;">GFP-like Proteins</a> <p>GFP-like proteins found in nature or engineered in the laboratory now span every color of the rainbow </p> </td> </tr> <tr> <td class="tn"><a href="/motm/42"><img src="https://cdn.rcsb.org/pdb101/motm/42/1gfl-tn.gif" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/42" style="font-size:16px;">Green Fluorescent Protein (GFP)</a> <p>A tiny fluorescent protein from jellyfish has revolutionized cell biology</p> </td> </tr> <tr> <td class="tn"><a href="/motm/131"><img src="https://cdn.rcsb.org/pdb101/motm/131/1jva-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/131" style="font-size:16px;">Inteins</a> <p>Inteins splice themselves out of larger protein chains</p> </td> </tr> <tr> <td class="tn"><a href="/motm/237"><img src="https://cdn.rcsb.org/pdb101/motm/237/237-Nanodiscs_and_HDL-6clz_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/237" style="font-size:16px;">Nanodiscs and HDL</a> <p>Nanodiscs conveniently package a small piece of membrane for experimental studies.</p> </td> </tr> <tr> <td class="tn"><a href="/motm/290"><img src="https://cdn.rcsb.org/pdb101/motm/290/7qv7_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/290" style="font-size:16px;">Nanowires</a> <p>Nanowires conduct electrons one at a time inside biological molecules.</p> </td> </tr> <tr> <td class="tn"><a href="/motm/232"><img src="https://cdn.rcsb.org/pdb101/motm/232/231-Proteins_and_Biominerals-1q8h_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/232" style="font-size:16px;">Proteins and Biominerals</a> <p>Small biomineral crystals are used to build bone, eggshells and even tiny compasses.</p> </td> </tr> <tr> <td class="tn"><a href="/motm/222"><img src="https://cdn.rcsb.org/pdb101/motm/222/221-Proteins_and_Nanoparticles-5et3_homepage-tn.png" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/222" style="font-size:16px;">Proteins and Nanoparticles</a> <p>Nanotech scientists are designing new ways to combine proteins and nanoparticles </p> </td> </tr> <tr> <td class="tn"><a href="/motm/161"><img src="https://cdn.rcsb.org/pdb101/motm/161/161-Ricin_2aai-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/161" style="font-size:16px;">Ricin</a> <p>The structure of ricin reveals how it kills cells and how vaccines can produce immunity against ricin poisoning</p> </td> </tr> <tr> <td class="tn"><a href="/motm/180"><img src="https://cdn.rcsb.org/pdb101/motm/180/180-TALEffectors_3ugm-tn.jpg" style="height:100%;" class="icon h-100 d-inline-block"></a></td> <td><a href="/motm/180" style="font-size:16px;">TAL Effectors</a> <p>TAL-effectors are modular, DNA-reading proteins that can be used to edit DNA in living cells</p> </td> </tr> </table> </div> </div> <h3>Learning Resources (3)</h3> <div id="learning-resources"> <div class="row grid-view"> <div style="display:block;" id="learn0" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/learn/paper-models/antibody" target="_self" class="no-underline"><img src="https://cdn.rcsb.org/pdb101/learn/images/tn/antibody-paper-model.png" style="height:100%;" class="icon h-100 d-inline-block"> <div>Antibody</div> <div><i>(Paper Model)</i></div></a></div> <div style="display:block;" id="learn1" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/learn/videos/artificial-lattice-of-a-designed-dna-crystal" target="_self" class="no-underline"><img src="https://cdn.rcsb.org/pdb101/learn/images/tn/lattice-anim.png" style="height:100%;" class="icon h-100 d-inline-block"> <div>Artificial lattice of a designed DNA crystal</div> <div><i>(GIF)</i></div></a></div> <div style="display:block;" id="learn2" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/learn/3d-printing/3d-print-green-fluorescent-protein" target="_self" class="no-underline"><img src="https://cdn.rcsb.org/pdb101/learn/images/tn/3d-printing-gfp.png" style="height:100%;" class="icon h-100 d-inline-block"> <div>3D Print: Green Fluorescent Protein</div> <div><i>(Other Resource)</i></div></a></div> </div> <div style="display:none;" class="list-view"> <table class="list-view"> <tr valign="top"> <td class="tn"><a href="/learn/paper-models/antibody" target="_self"><img src="https://cdn.rcsb.org/pdb101/learn/images/tn/antibody-paper-model.png" class="icon"></a></td> <td><a href="/learn/paper-models/antibody" target="_self" class="no-underline"><span style="font-size:16px;">Antibody</span> <div>Paper Model</div></a> <div>A paper folding activity that explores the structure of an antibody</div> </td> </tr> <tr valign="top"> <td class="tn"><a href="/learn/videos/artificial-lattice-of-a-designed-dna-crystal" target="_self"><img src="https://cdn.rcsb.org/pdb101/learn/images/tn/lattice-anim.png" class="icon"></a></td> <td><a href="/learn/videos/artificial-lattice-of-a-designed-dna-crystal" target="_self" class="no-underline"><span style="font-size:16px;">Artificial lattice of a designed DNA crystal</span> <div>GIF</div></a> <div>Designed DNA crystal: Small pieces of DNA have been engineered to form a nanoscale lattice.</div> </td> </tr> <tr valign="top"> <td class="tn"><a href="/learn/3d-printing/3d-print-green-fluorescent-protein" target="_self"><img src="https://cdn.rcsb.org/pdb101/learn/images/tn/3d-printing-gfp.png" class="icon"></a></td> <td><a href="/learn/3d-printing/3d-print-green-fluorescent-protein" target="_self" class="no-underline"><span style="font-size:16px;">3D Print: Green Fluorescent Protein</span> <div>Other Resource</div></a> <div>Download curated file of green fluorescent protein (GFP) for 3D printing</div> </td> </tr> </table> </div> </div> <h3>Structural Biology Highlights (2)</h3> <div id="structural-biology-highlights"> <div class="row grid-view"> <div style="display:block;" id="structuralBiologyHighlights0" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/learn/structural-biology-highlights/bacterial-armor" class="no-underline"><img src="https://cdn.rcsb.org/pdb101/learn/images/tn/structural-biology-highlights/3pyw.jpg" class="icon"> <div>Bacterial Armor</div></a></div> <div style="display:block;" id="structuralBiologyHighlights1" class="col-xs-6 col-sm-4 col-md-3 grid-cell"><a href="/learn/structural-biology-highlights/designer-proteins" class="no-underline"><img src="https://cdn.rcsb.org/pdb101/learn/images/tn/structural-biology-highlights/2lv8_figure.jpg" class="icon"> <div>Designer Proteins</div></a></div> </div> <div style="display:none;" class="list-view"> <table class="list-view"> <tr valign="top"> <td class="tn"><a href="/learn/structural-biology-highlights/bacterial-armor"><img src="https://cdn.rcsb.org/pdb101/learn/images/tn/structural-biology-highlights/3pyw.jpg" class="icon"></a></td> <td><a href="/learn/structural-biology-highlights/bacterial-armor" class="no-underline"><span style="font-size:16px;">Bacterial Armor</span></a> <div></div> </td> </tr> <tr valign="top"> <td class="tn"><a href="/learn/structural-biology-highlights/designer-proteins"><img src="https://cdn.rcsb.org/pdb101/learn/images/tn/structural-biology-highlights/2lv8_figure.jpg" class="icon"></a></td> <td><a href="/learn/structural-biology-highlights/designer-proteins" class="no-underline"><span style="font-size:16px;">Designer Proteins</span></a> <div></div> </td> </tr> </table> </div> </div> </div> </div> </div> <div id="footer_main" class="hidden-print"> <div 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