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href="/BlassanGeorge/mentions"><div class="stat-container"><p class="label">Mentions</p><p class="data">1</p></div></a><span><div class="stat-container"><p class="label"><span class="js-profile-total-view-text">Public Views</span></p><p class="data"><span class="js-profile-view-count"></span></p></div></span></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="10849334" href="https://www.academia.edu/Documents/in/_Zhuangzi_Jean_Francois_Billeter_"><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://independent.academia.edu/BlassanGeorge","location":"/BlassanGeorge","scheme":"https","host":"independent.academia.edu","port":null,"pathname":"/BlassanGeorge","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["莊子 Zhuangzi，畢來德Jean François Billeter，跨文化研究，跨文化批判，台灣民主政治"]}" data-trace="false" data-dom-id="Pill-react-component-7fcd1a8a-afea-4a16-af3d-18247579d487"></div> <div id="Pill-react-component-7fcd1a8a-afea-4a16-af3d-18247579d487"></div> </a></div></div></div></div><div class="right-panel-container"><div class="user-content-wrapper"><div class="uploads-container" id="social-redesign-work-container"><div class="upload-header"><h2 class="ds2-5-heading-sans-serif-xs">Uploads</h2></div><div class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by Blassan George</h3></div><div class="js-work-strip profile--work_container" data-work-id="114143514"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/114143514/%CE%B1_Glucosidase_%CE%B1_amylase_inhibition_kinetics_in_vitro_gastro_intestinal_digestion_and_apoptosis_inducing_abilities_of_Ficus_microcarpa_L_f_and_Ficus_racemosa_L_fruit_polysaccharides"><img alt="Research paper thumbnail of α-Glucosidase, α-amylase inhibition kinetics, in vitro gastro-intestinal digestion, and apoptosis inducing abilities of Ficus microcarpa L. f. and Ficus racemosa L. fruit polysaccharides" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/114143514/%CE%B1_Glucosidase_%CE%B1_amylase_inhibition_kinetics_in_vitro_gastro_intestinal_digestion_and_apoptosis_inducing_abilities_of_Ficus_microcarpa_L_f_and_Ficus_racemosa_L_fruit_polysaccharides">α-Glucosidase, α-amylase inhibition kinetics, in vitro gastro-intestinal digestion, and apoptosis inducing abilities of Ficus microcarpa L. f. and Ficus racemosa L. fruit polysaccharides</a></div><div class="wp-workCard_item"><span>Food Science and Biotechnology</span><span>, Sep 16, 2022</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="114143514"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span 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src="https://attachments.academia-assets.com/110919206/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/114143513/Potential_Application_of_Photosensitizers_With_High_Z_Elements_for_Synergic_Cancer_Therapy">Potential Application of Photosensitizers With High-Z Elements for Synergic Cancer Therapy</a></div><div class="wp-workCard_item"><span>Frontiers in Pharmacology</span><span>, Jun 28, 2022</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="606440f2dd6de202af92a113df26bf1a" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":110919206,"asset_id":114143513,"asset_type":"Work","button_location":"profile"}" 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href="https://www.academia.edu/114143511/Paradigm_shift_in_future_biophotonics_for_imaging_and_therapy_Miniature_living_lasers_to_cellular_scale_optoelectronics"><img alt="Research paper thumbnail of Paradigm shift in future biophotonics for imaging and therapy: Miniature living lasers to cellular scale optoelectronics" class="work-thumbnail" src="https://attachments.academia-assets.com/110919173/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/114143511/Paradigm_shift_in_future_biophotonics_for_imaging_and_therapy_Miniature_living_lasers_to_cellular_scale_optoelectronics">Paradigm shift in future biophotonics for imaging and therapy: Miniature living lasers to cellular scale optoelectronics</a></div><div class="wp-workCard_item"><span>Theranostics</span><span>, 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Root Acetone Extract</a></div><div class="wp-workCard_item"><span>Pharmacologia</span><span>, Mar 1, 2013</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b8138a436d4dcbf613c43e479848469d" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":110919204,"asset_id":114143509,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/110919204/download_file?st=MTczMjM3NDM1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="114143509"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="114143509"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 114143509; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=114143509]").text(description); $(".js-view-count[data-work-id=114143509]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 114143509; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='114143509']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 114143509, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b8138a436d4dcbf613c43e479848469d" } } $('.js-work-strip[data-work-id=114143509]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":114143509,"title":"Anti-inflammatory, Analgesic and Antipyretic Properties of Rubus niveus Thunb. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="114143508"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/114143508/Anti_inflammatory_and_wound_healing_properties_of_Rubus_fairholmianus_Gard_root_An_in_vivo_study"><img alt="Research paper thumbnail of Anti-inflammatory and wound healing properties of Rubus fairholmianus Gard. root—An in vivo study" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/114143508/Anti_inflammatory_and_wound_healing_properties_of_Rubus_fairholmianus_Gard_root_An_in_vivo_study">Anti-inflammatory and wound healing properties of Rubus fairholmianus Gard. root—An in vivo study</a></div><div class="wp-workCard_item"><span>Industrial Crops and Products</span><span>, Mar 1, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">ABSTRACT This study aims to develop an effective therapeutic agent from Rubus fairholmianus root ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">ABSTRACT This study aims to develop an effective therapeutic agent from Rubus fairholmianus root acetone extract (RFRA) against inflammatory related diseases as this plant is being used in folk medicine to treat various other ailments. The root acetone extract (up to 2000 mg/kg b. wt.) was used to observe acute toxicity in mice for 14 days. Two doses (200 and 400 mg/kg) were used to evaluate anti-inflammatory activity using carrageenan induced paw edema in rats and croton oil induced ear edema in mice. Both the doses significantly reduced the paw and ear edema compared to indomethacin. The acute dermal toxicity studies for RFRA extract were carried out and examined for wound healing activity at two doses (1% and 2%) in excision, incision, staphylococcus aureus infected and burn wound models in rat. RFRA 2% depicted significant wound healing properties; by increasing the percentage of wound contraction thereby by decreasing the period of epithelization compared with betadine (5%) and neomycin (5%). We have assumed that the peak shown close to the standard quercetin in the extract could be quercetin like compound (20.89 min). RFRA showed significant anti-inflammatory and wound healing properties which may be due to the presence of analogues of quercetin and other related polyphenolic compounds and hence it has immense scope as an effective source to develop a drug for the treatment of inflammatory related disorders.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="114143508"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="114143508"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 114143508; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=114143508]").text(description); $(".js-view-count[data-work-id=114143508]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 114143508; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='114143508']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 114143508, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=114143508]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":114143508,"title":"Anti-inflammatory and wound healing properties of Rubus fairholmianus Gard. root—An in vivo study","translated_title":"","metadata":{"abstract":"ABSTRACT This study aims to develop an effective therapeutic agent from Rubus fairholmianus root acetone extract (RFRA) against inflammatory related diseases as this plant is being used in folk medicine to treat various other ailments. 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Cancer Cell Death</a></div><div class="wp-workCard_item"><span>Anti-Cancer Agents in Medicinal Chemistry</span><span>, 2020</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Cancer refers to a collection of diseases where cells begin to multiply uncontrollabl...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Cancer refers to a collection of diseases where cells begin to multiply uncontrollably. Breast cancer is the most predominant malignancy in women. Herbal medicine is one of the important health care system in most of developing countries. Many studies have shown that naturally occurring compounds may support the prevention and treatment of various diseases, including cancer. Some of the plant extracts and isolated compounds shown photosensitizing activities and reduces cell proliferation whereas some revealed photoprotective effects. Objectives: The biological properties and medicinal uses of extracts and bioactive compounds from V. nilgiriensis have not been investigated. This study aims to evaluate the cytotoxic effects of V. nilgiriensis in combination with 680 nm laser irradiation on MCF-7 breast cancer cells. Methods: The inverted microscopy, ATP and LDH assay were used to analyze the cellular morphology, proliferation, cytotoxicity after the treatment with V. nilgi...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="114143502"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="114143502"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 114143502; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=114143502]").text(description); $(".js-view-count[data-work-id=114143502]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 114143502; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='114143502']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 114143502, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=114143502]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":114143502,"title":"Combined Effect of Vaccinium nilgiriensis Bark Extract and 680nm Laser Irradiation in Inducing Breast Cancer Cell Death","translated_title":"","metadata":{"abstract":"Background: Cancer refers to a collection of diseases where cells begin to multiply uncontrollably. 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Root</a></div><div class="wp-workCard_item"><span>Journal of Environmental Pathology Toxicology and Oncology</span><span>, 2014</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="114143510"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="114143510"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 114143510; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=114143510]").text(description); $(".js-view-count[data-work-id=114143510]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 114143510; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='114143510']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 114143510, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=114143510]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":114143510,"title":"Antitumor and Wound Healing Properties of Rubus niveus Thunb. 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Root Acetone Extract</a></div><div class="wp-workCard_item"><span>Pharmacologia</span><span>, Mar 1, 2013</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b8138a436d4dcbf613c43e479848469d" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":110919204,"asset_id":114143509,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/110919204/download_file?st=MTczMjM3NDM2MCw4LjIyMi4yMDguMTQ2&st=MTczMjM3NDM1OSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="114143509"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="114143509"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 114143509; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=114143509]").text(description); $(".js-view-count[data-work-id=114143509]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 114143509; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='114143509']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 114143509, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b8138a436d4dcbf613c43e479848469d" } } $('.js-work-strip[data-work-id=114143509]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":114143509,"title":"Anti-inflammatory, Analgesic and Antipyretic Properties of Rubus niveus Thunb. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="114143508"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/114143508/Anti_inflammatory_and_wound_healing_properties_of_Rubus_fairholmianus_Gard_root_An_in_vivo_study"><img alt="Research paper thumbnail of Anti-inflammatory and wound healing properties of Rubus fairholmianus Gard. root—An in vivo study" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/114143508/Anti_inflammatory_and_wound_healing_properties_of_Rubus_fairholmianus_Gard_root_An_in_vivo_study">Anti-inflammatory and wound healing properties of Rubus fairholmianus Gard. root—An in vivo study</a></div><div class="wp-workCard_item"><span>Industrial Crops and Products</span><span>, Mar 1, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">ABSTRACT This study aims to develop an effective therapeutic agent from Rubus fairholmianus root ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">ABSTRACT This study aims to develop an effective therapeutic agent from Rubus fairholmianus root acetone extract (RFRA) against inflammatory related diseases as this plant is being used in folk medicine to treat various other ailments. The root acetone extract (up to 2000 mg/kg b. wt.) was used to observe acute toxicity in mice for 14 days. Two doses (200 and 400 mg/kg) were used to evaluate anti-inflammatory activity using carrageenan induced paw edema in rats and croton oil induced ear edema in mice. Both the doses significantly reduced the paw and ear edema compared to indomethacin. The acute dermal toxicity studies for RFRA extract were carried out and examined for wound healing activity at two doses (1% and 2%) in excision, incision, staphylococcus aureus infected and burn wound models in rat. RFRA 2% depicted significant wound healing properties; by increasing the percentage of wound contraction thereby by decreasing the period of epithelization compared with betadine (5%) and neomycin (5%). We have assumed that the peak shown close to the standard quercetin in the extract could be quercetin like compound (20.89 min). RFRA showed significant anti-inflammatory and wound healing properties which may be due to the presence of analogues of quercetin and other related polyphenolic compounds and hence it has immense scope as an effective source to develop a drug for the treatment of inflammatory related disorders.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="114143508"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="114143508"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 114143508; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=114143508]").text(description); $(".js-view-count[data-work-id=114143508]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 114143508; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='114143508']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 114143508, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=114143508]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":114143508,"title":"Anti-inflammatory and wound healing properties of Rubus fairholmianus Gard. root—An in vivo study","translated_title":"","metadata":{"abstract":"ABSTRACT This study aims to develop an effective therapeutic agent from Rubus fairholmianus root acetone extract (RFRA) against inflammatory related diseases as this plant is being used in folk medicine to treat various other ailments. 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Properties of Rubus ellipticus and Rubus niveus" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/114143503/A_Comparative_Study_on_in_vitro_and_in_vivo_Antioxidant_Properties_of_Rubus_ellipticus_and_Rubus_niveus">A Comparative Study on in vitro and in vivo Antioxidant Properties of Rubus ellipticus and Rubus niveus</a></div><div class="wp-workCard_item"><span>Pharmacologia</span><span>, Jul 1, 2014</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper 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class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/114143502/Combined_Effect_of_Vaccinium_nilgiriensis_Bark_Extract_and_680nm_Laser_Irradiation_in_Inducing_Breast_Cancer_Cell_Death"><img alt="Research paper thumbnail of Combined Effect of Vaccinium nilgiriensis Bark Extract and 680nm Laser Irradiation in Inducing Breast Cancer Cell Death" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/114143502/Combined_Effect_of_Vaccinium_nilgiriensis_Bark_Extract_and_680nm_Laser_Irradiation_in_Inducing_Breast_Cancer_Cell_Death">Combined Effect of Vaccinium nilgiriensis Bark Extract and 680nm Laser Irradiation in Inducing Breast Cancer Cell Death</a></div><div class="wp-workCard_item"><span>Anti-Cancer Agents in Medicinal Chemistry</span><span>, 2020</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Background: Cancer refers to a collection of diseases where cells begin to multiply uncontrollabl...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Background: Cancer refers to a collection of diseases where cells begin to multiply uncontrollably. Breast cancer is the most predominant malignancy in women. Herbal medicine is one of the important health care system in most of developing countries. Many studies have shown that naturally occurring compounds may support the prevention and treatment of various diseases, including cancer. Some of the plant extracts and isolated compounds shown photosensitizing activities and reduces cell proliferation whereas some revealed photoprotective effects. Objectives: The biological properties and medicinal uses of extracts and bioactive compounds from V. nilgiriensis have not been investigated. This study aims to evaluate the cytotoxic effects of V. nilgiriensis in combination with 680 nm laser irradiation on MCF-7 breast cancer cells. Methods: The inverted microscopy, ATP and LDH assay were used to analyze the cellular morphology, proliferation, cytotoxicity after the treatment with V. nilgi...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="114143502"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="114143502"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 114143502; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=114143502]").text(description); $(".js-view-count[data-work-id=114143502]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 114143502; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='114143502']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 114143502, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=114143502]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":114143502,"title":"Combined Effect of Vaccinium nilgiriensis Bark Extract and 680nm Laser Irradiation in Inducing Breast Cancer Cell Death","translated_title":"","metadata":{"abstract":"Background: Cancer refers to a collection of diseases where cells begin to multiply uncontrollably. 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Methods: The inverted microscopy, ATP and LDH assay were used to analyze the cellular morphology, proliferation, cytotoxicity after the treatment with V. nilgi...","publisher":"Bentham Science Publishers Ltd.","publication_date":{"day":null,"month":null,"year":2020,"errors":{}},"publication_name":"Anti-Cancer Agents in Medicinal Chemistry"},"translated_abstract":"Background: Cancer refers to a collection of diseases where cells begin to multiply uncontrollably. Breast cancer is the most predominant malignancy in women. Herbal medicine is one of the important health care system in most of developing countries. Many studies have shown that naturally occurring compounds may support the prevention and treatment of various diseases, including cancer. Some of the plant extracts and isolated compounds shown photosensitizing activities and reduces cell proliferation whereas some revealed photoprotective effects. Objectives: The biological properties and medicinal uses of extracts and bioactive compounds from V. nilgiriensis have not been investigated. This study aims to evaluate the cytotoxic effects of V. nilgiriensis in combination with 680 nm laser irradiation on MCF-7 breast cancer cells. 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hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/114143501/The_role_of_photodynamic_therapy_on_multidrug_resistant_breast_cancer"><img alt="Research paper thumbnail of The role of photodynamic therapy on multidrug resistant breast cancer" class="work-thumbnail" src="https://attachments.academia-assets.com/110919165/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/114143501/The_role_of_photodynamic_therapy_on_multidrug_resistant_breast_cancer">The role of photodynamic therapy on multidrug resistant breast cancer</a></div><div class="wp-workCard_item"><span>Cancer Cell International</span><span>, 2019</span></div><div class="wp-workCard_item wp-workCard--actions"><span 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