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Articles in press |Immunobiology
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text-primary">Journal of Immunobiology</h1> <div class="row"> <div class="col"> <p class="mb-1">ISSN: 2476-1966 </p> </div> <div class="col"> Open Access </div> <!---languages drop down----> <div class="nav-item dropdown multi_lang j_multi_lang"> <a class="nav-link dropdown-toggle" href="#" id="multi_lang" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false">Language</a> <div class="dropdown-menu" aria-labelledby=""> <a class="dropdown-item" href="https://spanish.hilarispublisher.com/immunobiology/inpress.html" title="Spanish"> <img src="/admin/flags/spain.png">Spanish </a> <a class="dropdown-item" href="https://chinese.hilarispublisher.com/immunobiology/inpress.html" title="Chinese"> <img src="/admin/flags/china.png">Chinese </a> <a class="dropdown-item" href="https://russian.hilarispublisher.com/immunobiology/inpress.html" title="Russian"> <img src="/admin/flags/russia.png">Russian </a> <a class="dropdown-item" 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</span> </a> <img src="/assets/img/manuscript.svg" alt=".." width="50"> </div> </div> <div class="mt-2 cu_whatsapp"> <button type="button" class="btn btn-md btn-fb waves-effect waves-light bg-primary text-white cu_wtsapp"><span class="wow flash bg_cu p-4 rounded" data-wow-duration="2s" data-wow-delay="1s" data-wow-iteration="infinite"><i class="fab fa-whatsapp-square text-white pr-1"></i></span><span class="pl-3 pos_cl">+447897072958 </span> </button> </div> </div> </div> </header> <section class="container"> <div class="row"> <div class="col-12 col-sm a_tag_c"> <h2 class="font-size-7">Articles in press and Articles in process</h2> <!-- <h3 class="text-primary font-size-6 my-3 border-bottom-2 border-yellow-900 pb-2"> </h3> --> <ul class="list-group list-group-flush"> <div class="border-bottom-1 py-2"> <div class="d-flex w-100 justify-content-between mb-1"> <span class="align-self-center">Research Article</span> <span class="w-25 ml-4 text-right"> Pages: 1 - 6<br> </span> </div> <h3 class="font-size-4"><a href="https://www.hilarispublisher.com/open-access/synthesis-and-characterization-of-gold-nanoparticle-conjugated-recombinant-aprv2-of-emdichelobactor-nodosusem-and-its-immunogenici-95747.html" title="Synthesis and Characterization of Gold Nanoparticle Conjugated Recombinant Aprv2 of <em>Dichelobactor nodosus</em> and its Immunogenicity">Synthesis and Characterization of Gold Nanoparticle Conjugated Recombinant Aprv2 of <em>Dichelobactor nodosus</em> and its Immunogenicity</a></h3> <p class="mb-1 font-size-3 text-muted"> <i class="fas fa-user"></i> <a href='https://www.hilarispublisher.com/author/subhash-verma-32822' style='color:#555; border-bottom:1px dotted #CCC;' title='Subhash Verma'>Subhash Verma</a>*, <a href='https://www.hilarispublisher.com/author/geetanjali-singh-32823' style='color:#555; border-bottom:1px dotted #CCC;' title='Geetanjali Singh'>Geetanjali Singh</a>, <a href='https://www.hilarispublisher.com/author/mandeep-sharma-32824' style='color:#555; border-bottom:1px dotted #CCC;' title='Mandeep Sharma'>Mandeep Sharma</a>, <a href='https://www.hilarispublisher.com/author/pratiksha-srivastava-32825' style='color:#555; border-bottom:1px dotted #CCC;' title='Pratiksha Srivastava'>Pratiksha Srivastava</a>, <a href='https://www.hilarispublisher.com/author/richa-salwan-32826' style='color:#555; border-bottom:1px dotted #CCC;' title='Richa Salwan'>Richa Salwan</a> and <a href='https://www.hilarispublisher.com/author/chayan-nandi-32827' style='color:#555; border-bottom:1px dotted #CCC;' title='Chayan Nandi'>Chayan Nandi</a> </p> <p class="mb-1 font-size-3 text-muted">DOI: <a href="https://www.hilarispublisher.com/open-access/synthesis-and-characterization-of-gold-nanoparticle-conjugated-recombinant-aprv2-of-emdichelobactor-nodosusem-and-its-immunogenici-95747.html" title="Click here">10.37421/2476-1966.2023.8.186</a></p> <div class="row justify-content-between align-items-center"> <div class="col pl-0"> <a class="btn btn-link" data-toggle="collapse" href="#collapseAbstract95747" role="button" aria-expanded="false" aria-controls="collapseAbstract"> Preview Abstract </a> </div> <div class="col-12 col-sm-auto"> <nav class="nav a-mx-2"> <a href="https://www.hilarispublisher.com/abstract/synthesis-and-characterization-of-gold-nanoparticle-conjugated-recombinant-aprv2-of-emdichelobactor-nodosusem-and-its-im-95747.html" title="Abstract" class="card-link border-bottom-2 yellow-900 border-yellow-900"><i class="fas fa-file-alt fa-lg"></i> Abstract</a> <a href="https://www.hilarispublisher.com/open-access/synthesis-and-characterization-of-gold-nanoparticle-conjugated-recombinant-aprv2-of-emdichelobactor-nodosusem-and-its-immunogenici-95747.html" title="HTML" class="nav-link"><i class="fas fa-file-code fa-lg"></i> Full-Text</a> <a href="https://www.hilarispublisher.com/open-access/synthesis-and-characterization-of-gold-nanoparticle-conjugated--recombinant-aprv2-of-emdichelobactor-nodosusem-and-its-i.pdf" title="PDF" class="card-link border-bottom-2 border-blue-900"><i class="fas fa-file-pdf fa-lg"></i> PDF</a> </nav> </div> <div class="col-12 col-sm-auto"> <div class="d-flex align-items-center"> Share this article <nav class="nav a-px-2"> <a href="https://www.facebook.com/sharer.php?u=https://www.hilarispublisher.com/open-access/synthesis-and-characterization-of-gold-nanoparticle-conjugated-recombinant-aprv2-of-emdichelobactor-nodosusem-and-its-immunogenici-95747.html" class="nav-link" target="_blank"><i class="fab fa-facebook-f facebook"></i></a> <a href="https://twitter.com/share?url=https://www.hilarispublisher.com/open-access/synthesis-and-characterization-of-gold-nanoparticle-conjugated-recombinant-aprv2-of-emdichelobactor-nodosusem-and-its-immunogenici-95747.html" class="nav-link" target="_blank"><i class="fab fa-twitter twitter"></i></a> <a href="https://www.linkedin.com/shareArticle?mini=true&url=https://www.hilarispublisher.com/open-access/synthesis-and-characterization-of-gold-nanoparticle-conjugated-recombinant-aprv2-of-emdichelobactor-nodosusem-and-its-immunogenici-95747.html" class="nav-link" target="_blank"><i class="fab fa-linkedin-in linkedin"></i></a> <a href="https://pinterest.com/pin/create/button/?url=https://www.hilarispublisher.com/open-access/synthesis-and-characterization-of-gold-nanoparticle-conjugated-recombinant-aprv2-of-emdichelobactor-nodosusem-and-its-immunogenici-95747.html" class="nav-link" target="_blank"><i class="fab fa-pinterest-p pinterest"></i></a> <a href="https://www.blogger.com/blog-this.g?u=https://www.hilarispublisher.com/open-access/synthesis-and-characterization-of-gold-nanoparticle-conjugated-recombinant-aprv2-of-emdichelobactor-nodosusem-and-its-immunogenici-95747.html" class="nav-link" target="_blank"><i class="fab fa-blogger-b blogger"></i></a> </nav> </div> </div> </div> <div class="collapse" id="collapseAbstract95747"> <div class="card card-body p-2 bg-light"><p>The present study involves the synthesis, characterization and immunogenicity of Gold Nanoparticle (GNP) conjugated recombinant AprV2 protein of <em>Dichelobactor nodosus</em>. To achieve this, GNPs of size 20 nm were prepared and characterized. The gold nanoparticles effectively adsorbed 3.3 μg of recombinant AprV2 protein over the surface. TEM studies revealed corona of AprV2 over GNPs (1-2 nm thick) in GNPs-AprV2 conjugate. Further, GNP-AprV2 conjugate revealed a red shift from 523 nm to 532 nm, indicating increased size of GNPs after conjugation with AprV2. To evaluate the immunogenic response, mice were allotted to 5 different groups. Mice in group I injected with GNP-AprV2 conjugate, group II with GNP-AprV2 with MPLA (Monophosphoryl lipid A), group III with AprV2 on its own, group IV with GNPs and group V with Phosphate Buffered Saline (PBS). The highest antibody responses against the AprV2 were recorded in pooled sera from mice of group II compared to group me and III on day 28. Among all groups, the group II mice vaccinated with GNP-AprV2/ MPLA exhibited the highest IgG levels. The third dose of vaccine formulations did not enhance antibody levels. This study is a first report studying the immunogenic effect of conjugation of GNPs with rAprV2 of <em>D. nodosus</em>.</p></div> </div> </div> <div class="border-bottom-1 py-2"> <div class="d-flex w-100 justify-content-between mb-1"> <span class="align-self-center">Case Report</span> <span class="w-25 ml-4 text-right"> Pages: 1 - 3<br> </span> </div> <h3 class="font-size-4"><a href="https://www.hilarispublisher.com/open-access/kounis-syndrome-in-a-patient-following-astrazeneca-covid19-vaccination-95748.html" title="Kounis Syndrome in a Patient Following Astrazeneca COVID-19 Vaccination">Kounis Syndrome in a Patient Following Astrazeneca COVID-19 Vaccination</a></h3> <p class="mb-1 font-size-3 text-muted"> <i class="fas fa-user"></i> <a href='https://www.hilarispublisher.com/author/asif-mohamed-farook-32820' style='color:#555; border-bottom:1px dotted #CCC;' title='Asif Mohamed Farook'>Asif Mohamed Farook</a>* and <a href='https://www.hilarispublisher.com/author/dilshan-priyankara-32821' style='color:#555; border-bottom:1px dotted #CCC;' title='Dilshan Priyankara'>Dilshan Priyankara</a> </p> <p class="mb-1 font-size-3 text-muted">DOI: <a href="https://www.hilarispublisher.com/open-access/kounis-syndrome-in-a-patient-following-astrazeneca-covid19-vaccination-95748.html" title="Click here">10.37421/2476-1966.2023.8.185</a></p> <div class="row justify-content-between align-items-center"> <div class="col pl-0"> <a class="btn btn-link" data-toggle="collapse" href="#collapseAbstract95748" role="button" aria-expanded="false" aria-controls="collapseAbstract"> Preview Abstract </a> </div> <div class="col-12 col-sm-auto"> <nav class="nav a-mx-2"> <a href="https://www.hilarispublisher.com/abstract/kounis-syndrome-in-a-patient-following-astrazeneca-covid19-vaccination-95748.html" title="Abstract" class="card-link border-bottom-2 yellow-900 border-yellow-900"><i class="fas fa-file-alt fa-lg"></i> Abstract</a> <a href="https://www.hilarispublisher.com/open-access/kounis-syndrome-in-a-patient-following-astrazeneca-covid19-vaccination-95748.html" title="HTML" class="nav-link"><i class="fas fa-file-code fa-lg"></i> Full-Text</a> <a href="https://www.hilarispublisher.com/open-access/kounis-syndrome-in-a-patient-following-astrazeneca-covid19-vaccination.pdf" title="PDF" class="card-link border-bottom-2 border-blue-900"><i class="fas fa-file-pdf fa-lg"></i> PDF</a> </nav> </div> <div class="col-12 col-sm-auto"> <div class="d-flex align-items-center"> Share this article <nav class="nav a-px-2"> <a href="https://www.facebook.com/sharer.php?u=https://www.hilarispublisher.com/open-access/kounis-syndrome-in-a-patient-following-astrazeneca-covid19-vaccination-95748.html" class="nav-link" target="_blank"><i class="fab fa-facebook-f facebook"></i></a> <a href="https://twitter.com/share?url=https://www.hilarispublisher.com/open-access/kounis-syndrome-in-a-patient-following-astrazeneca-covid19-vaccination-95748.html" class="nav-link" target="_blank"><i class="fab fa-twitter twitter"></i></a> <a href="https://www.linkedin.com/shareArticle?mini=true&url=https://www.hilarispublisher.com/open-access/kounis-syndrome-in-a-patient-following-astrazeneca-covid19-vaccination-95748.html" class="nav-link" target="_blank"><i class="fab fa-linkedin-in linkedin"></i></a> <a href="https://pinterest.com/pin/create/button/?url=https://www.hilarispublisher.com/open-access/kounis-syndrome-in-a-patient-following-astrazeneca-covid19-vaccination-95748.html" class="nav-link" target="_blank"><i class="fab fa-pinterest-p pinterest"></i></a> <a href="https://www.blogger.com/blog-this.g?u=https://www.hilarispublisher.com/open-access/kounis-syndrome-in-a-patient-following-astrazeneca-covid19-vaccination-95748.html" class="nav-link" target="_blank"><i class="fab fa-blogger-b blogger"></i></a> </nav> </div> </div> </div> <div class="collapse" id="collapseAbstract95748"> <div class="card card-body p-2 bg-light"><p>Kounis syndrome also known as allergic angina syndrome is defined as the occurrence of an acute coronary syndrome concomitantly with hypersensitivity reaction. It was first described in 1991 by Kounis and Zavras. It is a rare syndrome and is often an under diagnosed phenomenon as physicians are unaware of the condition. We discuss a 54 years old female Sri Lankan patient who developed Kounis syndrome following Oxford Astra Zeneca COVID-19 vaccination. The patient initially developed anaphylaxis following the Astra Zeneca COVID-19 vaccine and subsequently developed acute coronary syndrome secondary to anaphylaxis. Patient was treated appropriately and eventually recovered from her condition. This syndrome should be suspected when there is concurrent acute coronary syndrome with allergic reactions. 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