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KEGG ENZYME: 1.5.1.45
<!doctype html> <html><head> <title>KEGG ENZYME: 1.5.1.45</title> <link type="text/css" rel="stylesheet" href="/css/gn2.css?1744084152"> <link type="text/css" rel="stylesheet" href="/css/bget.css?1744084152"> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link type="text/css" rel="stylesheet" href="/css/bgetm.css?1744084152" media="only screen and (max-width: 768px)"> <style>.kcfd{display:none;}</style> <script> <!-- var getElementsByClassName = document.getElementsByClassName ? function (cl){ return document.getElementsByClassName(cl); } : function (cl){ var elms = []; var objs = document.getElementsByTagName('*'); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(obj.className == cl){ elms.push(obj); } } return elms; }; function toggleField(clk,cl,show,hide){ var objs = getElementsByClassName(cl); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(!obj.style.display||obj.style.display == 'none'){ obj.style.display = 'block'; clk.innerHTML = ' « '+hide; 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} } } function Link_XtrctSeq2(form) { var dna_from; var dna_to; var dna_len; var plus_up = Number(form.XtrctSeq_UP.value) ; var plus_down = Number(form.XtrctSeq_DOWN.value); var vector = Number(form.VECTOR.value); var org = form.ORG.value; var chr = form.CHR.value; var kid = form.KEGGID.value; var url; if (plus_up == 0 && plus_down == 0) { url = "/entry/-f+-n+n+" + kid; } else { if (vector == 1) { dna_from = Number(form.FROM.value) - plus_up; dna_to = Number(form.TO.value) + plus_down; } else { dna_from = Number(form.FROM.value) - plus_down; dna_to = Number(form.TO.value) + plus_up; } url = "/dbget-bin/cut_sequence_genes.pl?FROM=" + dna_from + "&TO=" + dna_to +"&VECTOR=" + vector + "&ORG=" + org; if (chr) url += "&CHR=" + chr; } //window.open( url, "_self" ); location.href = url; } function go_taxonomy(form,params){ for(var key in params){ if(form[key]){ form.setAttribute(key,params[key]); } else{ var obj = document.createElement('input'); obj.setAttribute('type','hidden'); obj.setAttribute('name',key); obj.setAttribute('value',params[key]); form.appendChild(obj); } } form.submit(); } window.onload=function(){window.focus();init();}; //---> </script> </head> <body> <div> <table border=0 cellpadding=0 cellspacing=0><tr><td> <table border=0 cellpadding=0 cellspacing=0 width="683"><tr><td width=70><a href="/kegg/kegg2.html"><img align="middle" alt="KEGG" border=0 src="/Fig/bget/kegg2.gif"></a></td><td> </td><td><a name="enzyme:1.5.1.45"></a><font class="title2">ENZYME: 1.5.1.45</font></td><td class="tar vbot"><button class="btn" onclick="javascript:void(window.open('/kegg/document/help_bget_enzyme.html','KEGG_Help','toolbar=no,location=no,directories=no,width=720,height=640,resizable=yes,scrollbars=yes'));return false;">Help</button></td></tr></table><form method="post" action="/kegg-bin/search_htext" enctype="application/x-www-form-urlencoded" id="form1" name="form1"></form><table class="w1" width="650"> <tr> <td class="fr2 w1"> <table width="650" class="w2"> <tr><th class="th20 deft tal vmid"><span class="nowrap">Entry</span></th> <td class="td20 defd"><table class="w1" width="100%"><tr><td class="tal pd0"><code><span class="nowrap">EC 1.5.1.45 Enzyme <br> </span></code></td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Name</span></th> <td class="td21 defd"><div class="cel"><div class="cel">FAD reductase [NAD(P)H];<br> GTNG_3158 (gene name)<br> </div></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Class</span></th> <td class="td20 defd"><div class="cel">Oxidoreductases;<br> Acting on the CH-NH group of donors;<br> With NAD+ or NADP+ as acceptor<br> <button class="btn" onclick="location.href='/brite/ko01000+1.5.1.45';return false;">BRITE hierarchy</button></div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Sysname</span></th> <td class="td21 defd"><div class="cel">FADH2:NAD(P)+ oxidoreductase<br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Reaction(IUBMB)</span></th> <td class="td20 defd"><div class="cel">FADH2 + NAD(P)+ = FAD + NAD(P)H + H+ [RN:<a href="/entry/R09520">R09520</a> <a href="/entry/R09748">R09748</a>]<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Reaction(KEGG)</span></th> <td class="td21 defd"><div class="cel"><a href="/entry/R09520">R09520</a> <a href="/entry/R09748">R09748</a><br> <button class="btn" onclick="location.href='/entry/R09520/R09748';return false;">Reaction</button></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Substrate</span></th> <td class="td20 defd"><div class="cel">FADH2 [CPD:<a href="/entry/C01352">C01352</a>];<br> NAD+ [CPD:<a href="/entry/C00003">C00003</a>];<br> NADP+ [CPD:<a href="/entry/C00006">C00006</a>]<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Product</span></th> <td class="td21 defd"><div class="cel"><div class="cel">FAD [CPD:<a href="/entry/C00016">C00016</a>];<br> NADH [CPD:<a href="/entry/C00004">C00004</a>];<br> NADPH [CPD:<a href="/entry/C00005">C00005</a>];<br> H+ [CPD:<a href="/entry/C00080">C00080</a>]<br> </div></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Comment</span></th> <td class="td20 defd"><div class="cel">This enzyme, isolated from the bacterium Geobacillus thermodenitrificans, participates in the pathway of tryptophan degradation. The enzyme is part of a system that also includes a bifunctional riboflavin kinase/FMN adenylyltransferase and EC <a href="/entry/1.14.14.8">1.14.14.8</a>, anthranilate 3-monooxygenase (FAD). It can reduce either FAD or flavin mononucleotide (FMN) but prefers FAD. The enzyme has a slight preference for NADPH as acceptor. cf. EC <a href="/entry/1.5.1.37">1.5.1.37</a>, FAD reductase (NADH).<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">History</span></th> <td class="td21 defd"><div class="cel">EC 1.5.1.45 created 2012<br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Pathway</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/ec00740+1.5.1.45">ec00740</a> </span></td><td>Riboflavin metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/ec01100+1.5.1.45">ec01100</a> </span></td><td>Metabolic pathways</td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Orthology</span></th> <td class="td21 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/entry/K16902">K16902</a> </span></td><td>FAD reductase [NAD(P)H]</td></tr></table></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Genes</span></th> <td class="td20 defd"><style>span.g1a{color:#003399}span.g1a:hover{color:#33cc99;cursor:pointer;}div.g1{display:none;}</style><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g11">BMET</span>: </span></td><td id="g11d">BMMGA3_15280</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g12">GST</span>: </span></td><td id="g12d">HW35_13015</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g13">BACO</span>: </span></td><td id="g13d">OXB_0115</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g14">BASB</span>: </span></td><td id="g14d">M662_01960</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g15">NTX</span>: </span></td><td id="g15d">NQZ71_16505</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g16">NIL</span>: </span></td><td id="g16d">L8T27_005470</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g17">NTGC</span>: </span></td><td id="g17d">AB3U99_08295</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g18">BMQ</span>: </span></td><td id="g18d">BMQ_3594</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g19">BMD</span>: </span></td><td id="g19d">BMD_3579</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g110">BMEG</span>: </span></td><td id="g110d">BG04_468</td></tr></table><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g111">BKO</span>: </span></td><td id="g111d">CKF48_21905</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g112">CSOA</span>: </span></td><td id="g112d">LIS82_16125</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g113">BDA</span>: </span></td><td id="g113d">FSZ17_13420</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g114">OJD</span>: </span></td><td id="g114d">NP439_16250</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g115">OON</span>: </span></td><td id="g115d">NP440_15125</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g116">LYP</span>: </span></td><td id="g116d">MTP04_05370 MTP04_06180</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g117">HNZ</span>: </span></td><td id="g117d">P9989_01650 P9989_02080</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g118">HSAN</span>: </span></td><td id="g118d">MUN89_21615</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g119">HSHI</span>: </span></td><td id="g119d">MUO14_14530</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g120">HAMY</span>: </span></td><td id="g120d">MUO15_11750 MUO15_12285</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g121">VNT</span>: </span></td><td id="g121d">OLD84_18510</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g122">VIK</span>: </span></td><td id="g122d">KFZ58_18400</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g123">VSS</span>: </span></td><td id="g123d">PD280_20005</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g124">SAPL</span>: </span></td><td id="g124d">U0355_13440</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g125">APAK</span>: </span></td><td id="g125d">AP3564_00250</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g126">BMUR</span>: </span></td><td id="g126d">ABE28_004135</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g127">PASA</span>: </span></td><td id="g127d">BAOM_0491</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g128">PFRI</span>: </span></td><td id="g128d">L8956_02840</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g129">PERI</span>: </span></td><td id="g129d">RE409_29385</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g130">RAX</span>: </span></td><td id="g130d">KO561_06640 KO561_15520</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g131">MLIT</span>: </span></td><td id="g131d">KDJ21_024660</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g132">MENL</span>: </span></td><td id="g132d">MVE64_20290</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g133">MEBZ</span>: </span></td><td id="g133d">LPC09_06290</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g134">BVJ</span>: </span></td><td id="g134d">I5776_05115</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g135">BOU</span>: </span></td><td id="g135d">I5818_06410</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g136">HSPO</span>: </span></td><td id="g136d">JGZ69_11790</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g137">MSUT</span>: </span></td><td id="g137d">LC048_10450</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g138">DOM</span>: </span></td><td id="g138d">RRU94_06045 RRU94_18790</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g139">GTN</span>: </span></td><td id="g139d">GTNG_3158</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g140">GMC</span>: </span></td><td id="g140d">GY4MC1_3653</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g141">PTL</span>: </span></td><td id="g141d">AOT13_04015</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g142">BHUI</span>: </span></td><td id="g142d">LOK74_00570 LOK74_23405</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g143">BAYD</span>: </span></td><td id="g143d">BSPP4475_07425</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g144">BBOR</span>: </span></td><td id="g144d">RFB14_22190</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g145">BRUM</span>: </span></td><td id="g145d">NDK47_11220</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g146">ASED</span>: </span></td><td id="g146d">IRT44_17660</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g147">PBJ</span>: </span></td><td id="g147d">VN24_18680 VN24_25630</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g148">PNP</span>: </span></td><td id="g148d">IJ22_33750</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g149">PTHI</span>: </span></td><td id="g149d">NDS46_13530</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g150">PMAH</span>: </span></td><td id="g150d">PTQ21_20410</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g151">PDY</span>: </span></td><td id="g151d">QJQ58_08510</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g152">PSPN</span>: </span></td><td id="g152d">L1F29_06950</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g153">PPAB</span>: </span></td><td id="g153d">KET34_16295</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g154">PEZZ</span>: </span></td><td id="g154d">HW560_23515</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g155">PLIG</span>: </span></td><td id="g155d">NAG76_11950</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g156">EFF</span>: </span></td><td id="g156d">skT53_06260</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g157">SSIL</span>: </span></td><td id="g157d">SOLI23_13720</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g158">STHO</span>: </span></td><td id="g158d">QNH10_00625</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g159">STRB</span>: </span></td><td id="g159d">QWT68_10895</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g160">SOW</span>: </span></td><td id="g160d">QWT69_02010</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g161">SJT</span>: </span></td><td id="g161d">PGH26_01330</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g162">UTH</span>: </span></td><td id="g162d">DKZ56_04195</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g163">ACTY</span>: </span></td><td id="g163d">OG774_22995</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g164">HSAI</span>: </span></td><td id="g164d">HPS36_14230</td></tr></table></div><div class="g1"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><span class="g1a" id="g165">NARA</span>: </span></td><td id="g165d">QQ977_12260</td></tr></table></div><a 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onclick="javascript:go_taxonomy(document.form1,{"action":"/kegg-bin/search_htext"});return false;">Taxonomy</button></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Reference</span></th> <td class="td21 defd"><div class="cel">1 [PMID:<a href="https://www.ncbi.nlm.nih.gov/pubmed/19942660">19942660</a>]</div></td></tr> <tr><th class="th20 rept tal vtop"><span class="nowrap"> Authors</span></th> <td class="td20 repd"><div class="cel">Liu X, Dong Y, Li X, Ren Y, Li Y, Wang W, Wang L, Feng L</div></td></tr> <tr><th class="th21 rept tal vtop"><span class="nowrap"> Title</span></th> <td class="td21 repd"><div class="cel">Characterization of the anthranilate degradation pathway in Geobacillus thermodenitrificans NG80-2.</div></td></tr> <tr><th class="th20 rept tal vtop"><span class="nowrap"> Journal</span></th> <td class="td20 repd"><div class="cel">Microbiology 156:589-95 (2010)<br>DOI:<a href="https://doi.org/10.1099/mic.0.031880-0">10.1099/mic.0.031880-0</a></div></td></tr> <tr><th class="th21 rept tal vtop"><span class="nowrap"> Sequence</span></th> <td class="td21 repd"><div class="cel">[gtn:<a href="/entry/gtn:GTNG_3158">GTNG_3158</a>]</div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Other DBs</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">ExplorEnz - The Enzyme Database: </span></td><td><a href="https://www.enzyme-database.org/query.php?ec=1.5.1.45">1.5.1.45</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">IUBMB Enzyme Nomenclature: </span></td><td><a href="https://iubmb.qmul.ac.uk/enzyme/EC1/5/1/45.html">1.5.1.45</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">ExPASy - ENZYME nomenclature database: </span></td><td><a href="https://enzyme.expasy.org/EC/1.5.1.45">1.5.1.45</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">BRENDA, the Enzyme Database: </span></td><td><a href="https://www.brenda-enzymes.info/enzyme.php?ecno=1.5.1.45">1.5.1.45</a></td></tr></table></td></tr> <tr><th class="th21 deft tal vmid"><span class="nowrap">LinkDB</span></th> <td class="td21 defd"><button class="btn" onclick="location.href='https://www.genome.jp/dbget-bin/get_linkdb?enzyme+1.5.1.45';return false;">All DBs</button></td></tr> </table></td></tr></table> <br></td></tr></table> <a href="/dbget/">DBGET</a> integrated database retrieval system</div> </body> </html>