CD20 Antibody Pair (H00000931-AP22): Novus Biologicals

<!DOCTYPE html> <html> <head> <meta charset="UTF-8"><script type="text/javascript">(window.NREUM||(NREUM={})).init={privacy:{cookies_enabled:true},ajax:{deny_list:[]},session_replay:{sampling_rate:10.0,mask_text_selector:"",block_selector:"",mask_input_options:{date:true,text_area:true,week:true,select:true,color:true,range:true,textarea:true,url:true,number:true,search:true,month:true,datetime_local:true,tel:true,text:true,time:true,email:true},enabled:true,error_sampling_rate:100.0}};(window.NREUM||(NREUM={})).loader_config={xpid:"UA8FUVBADwsIV1VaAgQD",licenseKey:"76fb58fb05",applicationID:"788348554"};;/*! For license information please see nr-loader-full-1.274.0.min.js.LICENSE.txt */ (()=>{var e,t,r={8122:(e,t,r)=>{"use strict";r.d(t,{a:()=>i});var n=r(944);function i(e,t){try{if(!e||"object"!=typeof e)return(0,n.R)(3);if(!t||"object"!=typeof t)return(0,n.R)(4);const r=Object.create(Object.getPrototypeOf(t),Object.getOwnPropertyDescriptors(t)),o=0===Object.keys(r).length?e:r;for(let a in o)if(void 0!==e[a])try{if(null===e[a]){r[a]=null;continue}Array.isArray(e[a])&&Array.isArray(t[a])?r[a]=Array.from(new Set([...e[a],...t[a]])):"object"==typeof e[a]&&"object"==typeof t[a]?r[a]=i(e[a],t[a]):r[a]=e[a]}catch(e){(0,n.R)(1,e)}return r}catch(e){(0,n.R)(2,e)}}},2555:(e,t,r)=>{"use strict";r.d(t,{Vp:()=>c,fn:()=>s,x1:()=>d});var n=r(384),i=r(8122);const o={beacon:n.NT.beacon,errorBeacon:n.NT.errorBeacon,licenseKey:void 0,applicationID:void 0,sa:void 0,queueTime:void 0,applicationTime:void 0,ttGuid:void 0,user:void 0,account:void 0,product:void 0,extra:void 0,jsAttributes:{},userAttributes:void 0,atts:void 0,transactionName:void 0,tNamePlain:void 0},a={};function s(e){try{const t=c(e);return!!t.licenseKey&&!!t.errorBeacon&&!!t.applicationID}catch(e){return!1}}function c(e){if(!e)throw new Error("All info objects require an agent identifier!");if(!a[e])throw new Error("Info for ".concat(e," was never set"));return a[e]}function d(e,t){if(!e)throw new Error("All info objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.info=a[e])}},9417:(e,t,r)=>{"use strict";r.d(t,{D0:()=>h,gD:()=>p,xN:()=>g});var n=r(993);const i=e=>{if(!e||"string"!=typeof e)return!1;try{document.createDocumentFragment().querySelector(e)}catch{return!1}return!0};var o=r(2614),a=r(944),s=r(384),c=r(8122);const d="[data-nr-mask]",u=()=>{const e={mask_selector:"*",block_selector:"[data-nr-block]",mask_input_options:{color:!1,date:!1,"datetime-local":!1,email:!1,month:!1,number:!1,range:!1,search:!1,tel:!1,text:!1,time:!1,url:!1,week:!1,textarea:!1,select:!1,password:!0}};return{ajax:{deny_list:void 0,block_internal:!0,enabled:!0,harvestTimeSeconds:10,autoStart:!0},distributed_tracing:{enabled:void 0,exclude_newrelic_header:void 0,cors_use_newrelic_header:void 0,cors_use_tracecontext_headers:void 0,allowed_origins:void 0},feature_flags:[],generic_events:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},harvest:{tooManyRequestsDelay:60},jserrors:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},logging:{enabled:!0,harvestTimeSeconds:10,autoStart:!0,level:n.p_.INFO},metrics:{enabled:!0,autoStart:!0},obfuscate:void 0,page_action:{enabled:!0},page_view_event:{enabled:!0,autoStart:!0},page_view_timing:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},performance:{capture_marks:!1,capture_measures:!1},privacy:{cookies_enabled:!0},proxy:{assets:void 0,beacon:void 0},session:{expiresMs:o.wk,inactiveMs:o.BB},session_replay:{autoStart:!0,enabled:!1,harvestTimeSeconds:60,preload:!1,sampling_rate:10,error_sampling_rate:100,collect_fonts:!1,inline_images:!1,fix_stylesheets:!0,mask_all_inputs:!0,get mask_text_selector(){return e.mask_selector},set mask_text_selector(t){i(t)?e.mask_selector="".concat(t,",").concat(d):""===t||null===t?e.mask_selector=d:(0,a.R)(5,t)},get block_class(){return"nr-block"},get ignore_class(){return"nr-ignore"},get mask_text_class(){return"nr-mask"},get block_selector(){return e.block_selector},set block_selector(t){i(t)?e.block_selector+=",".concat(t):""!==t&&(0,a.R)(6,t)},get mask_input_options(){return e.mask_input_options},set mask_input_options(t){t&&"object"==typeof t?e.mask_input_options={...t,password:!0}:(0,a.R)(7,t)}},session_trace:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},soft_navigations:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},spa:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},ssl:void 0,user_actions:{enabled:!0}}},l={},f="All configuration objects require an agent identifier!";function h(e){if(!e)throw new Error(f);if(!l[e])throw new Error("Configuration for ".concat(e," was never set"));return l[e]}function g(e,t){if(!e)throw new Error(f);l[e]=(0,c.a)(t,u());const r=(0,s.nY)(e);r&&(r.init=l[e])}function p(e,t){if(!e)throw new Error(f);var r=h(e);if(r){for(var n=t.split("."),i=0;i<n.length-1;i++)if("object"!=typeof(r=r[n[i]]))return;r=r[n[n.length-1]]}return r}},5603:(e,t,r)=>{"use strict";r.d(t,{a:()=>c,o:()=>s});var n=r(384),i=r(8122);const o={accountID:void 0,trustKey:void 0,agentID:void 0,licenseKey:void 0,applicationID:void 0,xpid:void 0},a={};function s(e){if(!e)throw new Error("All loader-config objects require an agent identifier!");if(!a[e])throw new Error("LoaderConfig for ".concat(e," was never set"));return a[e]}function c(e,t){if(!e)throw new Error("All loader-config objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.loader_config=a[e])}},3371:(e,t,r)=>{"use strict";r.d(t,{V:()=>f,f:()=>l});var n=r(8122),i=r(384),o=r(6154),a=r(9324);let s=0;const c={buildEnv:a.F3,distMethod:a.Xs,version:a.xv,originTime:o.WN},d={customTransaction:void 0,disabled:!1,isolatedBacklog:!1,loaderType:void 0,maxBytes:3e4,onerror:void 0,ptid:void 0,releaseIds:{},appMetadata:{},session:void 0,denyList:void 0,timeKeeper:void 0,obfuscator:void 0},u={};function l(e){if(!e)throw new Error("All runtime objects require an agent identifier!");if(!u[e])throw new Error("Runtime for ".concat(e," was never set"));return u[e]}function f(e,t){if(!e)throw new Error("All runtime objects require an agent identifier!");u[e]={...(0,n.a)(t,d),...c},Object.hasOwnProperty.call(u[e],"harvestCount")||Object.defineProperty(u[e],"harvestCount",{get:()=>++s});const r=(0,i.nY)(e);r&&(r.runtime=u[e])}},9324:(e,t,r)=>{"use strict";r.d(t,{F3:()=>i,Xs:()=>o,Yq:()=>a,xv:()=>n});const n="1.274.0",i="PROD",o="CDN",a="^2.0.0-alpha.17"},6154:(e,t,r)=>{"use strict";r.d(t,{OF:()=>d,RI:()=>i,WN:()=>f,bv:()=>o,gm:()=>a,lR:()=>l,m:()=>c,mw:()=>s,sb:()=>u});var n=r(1863);const i="undefined"!=typeof window&&!!window.document,o="undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self.navigator instanceof WorkerNavigator||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis.navigator instanceof WorkerNavigator),a=i?window:"undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis),s=Boolean("hidden"===a?.document?.visibilityState),c=""+a?.location,d=/iPad|iPhone|iPod/.test(a.navigator?.userAgent),u=d&&"undefined"==typeof SharedWorker,l=(()=>{const e=a.navigator?.userAgent?.match(/Firefox[/\s](\d+\.\d+)/);return Array.isArray(e)&&e.length>=2?+e[1]:0})(),f=Date.now()-(0,n.t)()},7295:(e,t,r)=>{"use strict";r.d(t,{Xv:()=>a,gX:()=>i,iW:()=>o});var n=[];function i(e){if(!e||o(e))return!1;if(0===n.length)return!0;for(var t=0;t<n.length;t++){var r=n[t];if("*"===r.hostname)return!1;if(s(r.hostname,e.hostname)&&c(r.pathname,e.pathname))return!1}return!0}function o(e){return void 0===e.hostname}function a(e){if(n=[],e&&e.length)for(var t=0;t<e.length;t++){let r=e[t];if(!r)continue;0===r.indexOf("http://")?r=r.substring(7):0===r.indexOf("https://")&&(r=r.substring(8));const i=r.indexOf("/");let o,a;i>0?(o=r.substring(0,i),a=r.substring(i)):(o=r,a="");let[s]=o.split(":");n.push({hostname:s,pathname:a})}}function s(e,t){return!(e.length>t.length)&&t.indexOf(e)===t.length-e.length}function c(e,t){return 0===e.indexOf("/")&&(e=e.substring(1)),0===t.indexOf("/")&&(t=t.substring(1)),""===e||e===t}},1687:(e,t,r)=>{"use strict";r.d(t,{Ak:()=>c,Ze:()=>l,x3:()=>d});var n=r(7836),i=r(3606),o=r(860),a=r(2646);const s={};function c(e,t){const r={staged:!1,priority:o.P3[t]||0};u(e),s[e].get(t)||s[e].set(t,r)}function d(e,t){e&&s[e]&&(s[e].get(t)&&s[e].delete(t),h(e,t,!1),s[e].size&&f(e))}function u(e){if(!e)throw new Error("agentIdentifier required");s[e]||(s[e]=new Map)}function l(e="",t="feature",r=!1){if(u(e),!e||!s[e].get(t)||r)return h(e,t);s[e].get(t).staged=!0,f(e)}function f(e){const t=Array.from(s[e]);t.every((([e,t])=>t.staged))&&(t.sort(((e,t)=>e[1].priority-t[1].priority)),t.forEach((([t])=>{s[e].delete(t),h(e,t)})))}function h(e,t,r=!0){const o=e?n.ee.get(e):n.ee,s=i.i.handlers;if(!o.aborted&&o.backlog&&s){if(r){const e=o.backlog[t],r=s[t];if(r){for(let t=0;e&&t<e.length;++t)g(e[t],r);Object.entries(r).forEach((([e,t])=>{Object.values(t||{}).forEach((t=>{t[0]?.on&&t[0]?.context()instanceof a.y&&t[0].on(e,t[1])}))}))}}o.isolatedBacklog||delete s[t],o.backlog[t]=null,o.emit("drain-"+t,[])}}function g(e,t){var r=e[1];Object.values(t[r]||{}).forEach((t=>{var r=e[0];if(t[0]===r){var n=t[1],i=e[3],o=e[2];n.apply(i,o)}}))}},7836:(e,t,r)=>{"use strict";r.d(t,{P:()=>c,ee:()=>d});var n=r(384),i=r(8990),o=r(3371),a=r(2646),s=r(5607);const c="nr@context:".concat(s.W),d=function e(t,r){var n={},s={},u={},l=!1;try{l=16===r.length&&(0,o.f)(r).isolatedBacklog}catch(e){}var f={on:g,addEventListener:g,removeEventListener:function(e,t){var r=n[e];if(!r)return;for(var i=0;i<r.length;i++)r[i]===t&&r.splice(i,1)},emit:function(e,r,n,i,o){!1!==o&&(o=!0);if(d.aborted&&!i)return;t&&o&&t.emit(e,r,n);for(var a=h(n),c=p(e),u=c.length,l=0;l<u;l++)c[l].apply(a,r);var g=v()[s[e]];g&&g.push([f,e,r,a]);return a},get:m,listeners:p,context:h,buffer:function(e,t){const r=v();if(t=t||"feature",f.aborted)return;Object.entries(e||{}).forEach((([e,n])=>{s[n]=t,t in r||(r[t]=[])}))},abort:function(){f._aborted=!0,Object.keys(f.backlog).forEach((e=>{delete f.backlog[e]}))},isBuffering:function(e){return!!v()[s[e]]},debugId:r,backlog:l?{}:t&&"object"==typeof t.backlog?t.backlog:{},isolatedBacklog:l};return Object.defineProperty(f,"aborted",{get:()=>{let e=f._aborted||!1;return e||(t&&(e=t.aborted),e)}}),f;function h(e){return e&&e instanceof a.y?e:e?(0,i.I)(e,c,(()=>new a.y(c))):new a.y(c)}function g(e,t){n[e]=p(e).concat(t)}function p(e){return n[e]||[]}function m(t){return u[t]=u[t]||e(f,t)}function v(){return f.backlog}}(void 0,"globalEE"),u=(0,n.Zm)();u.ee||(u.ee=d)},2646:(e,t,r)=>{"use strict";r.d(t,{y:()=>n});class n{constructor(e){this.contextId=e}}},9908:(e,t,r)=>{"use strict";r.d(t,{d:()=>n,p:()=>i});var n=r(7836).ee.get("handle");function i(e,t,r,i,o){o?(o.buffer([e],i),o.emit(e,t,r)):(n.buffer([e],i),n.emit(e,t,r))}},3606:(e,t,r)=>{"use strict";r.d(t,{i:()=>o});var n=r(9908);o.on=a;var i=o.handlers={};function o(e,t,r,o){a(o||n.d,i,e,t,r)}function a(e,t,r,i,o){o||(o="feature"),e||(e=n.d);var a=t[o]=t[o]||{};(a[r]=a[r]||[]).push([e,i])}},3878:(e,t,r)=>{"use strict";function n(e,t){return{capture:e,passive:!1,signal:t}}function i(e,t,r=!1,i){window.addEventListener(e,t,n(r,i))}function o(e,t,r=!1,i){document.addEventListener(e,t,n(r,i))}r.d(t,{DD:()=>o,jT:()=>n,sp:()=>i})},5607:(e,t,r)=>{"use strict";r.d(t,{W:()=>n});const n=(0,r(9566).bz)()},9566:(e,t,r)=>{"use strict";r.d(t,{LA:()=>s,ZF:()=>c,bz:()=>a,el:()=>d});var n=r(6154);const i="xxxxxxxx-xxxx-4xxx-yxxx-xxxxxxxxxxxx";function o(e,t){return e?15&e[t]:16*Math.random()|0}function a(){const e=n.gm?.crypto||n.gm?.msCrypto;let t,r=0;return e&&e.getRandomValues&&(t=e.getRandomValues(new Uint8Array(30))),i.split("").map((e=>"x"===e?o(t,r++).toString(16):"y"===e?(3&o()|8).toString(16):e)).join("")}function s(e){const t=n.gm?.crypto||n.gm?.msCrypto;let r,i=0;t&&t.getRandomValues&&(r=t.getRandomValues(new Uint8Array(e)));const a=[];for(var s=0;s<e;s++)a.push(o(r,i++).toString(16));return a.join("")}function c(){return s(16)}function d(){return s(32)}},2614:(e,t,r)=>{"use strict";r.d(t,{BB:()=>a,H3:()=>n,g:()=>d,iL:()=>c,tS:()=>s,uh:()=>i,wk:()=>o});const n="NRBA",i="SESSION",o=144e5,a=18e5,s={STARTED:"session-started",PAUSE:"session-pause",RESET:"session-reset",RESUME:"session-resume",UPDATE:"session-update"},c={SAME_TAB:"same-tab",CROSS_TAB:"cross-tab"},d={OFF:0,FULL:1,ERROR:2}},1863:(e,t,r)=>{"use strict";function n(){return Math.floor(performance.now())}r.d(t,{t:()=>n})},7485:(e,t,r)=>{"use strict";r.d(t,{D:()=>i});var n=r(6154);function i(e){if(0===(e||"").indexOf("data:"))return{protocol:"data"};try{const t=new URL(e,location.href),r={port:t.port,hostname:t.hostname,pathname:t.pathname,search:t.search,protocol:t.protocol.slice(0,t.protocol.indexOf(":")),sameOrigin:t.protocol===n.gm?.location?.protocol&&t.host===n.gm?.location?.host};return r.port&&""!==r.port||("http:"===t.protocol&&(r.port="80"),"https:"===t.protocol&&(r.port="443")),r.pathname&&""!==r.pathname?r.pathname.startsWith("/")||(r.pathname="/".concat(r.pathname)):r.pathname="/",r}catch(e){return{}}}},944:(e,t,r)=>{"use strict";function n(e,t){"function"==typeof console.debug&&console.debug("New Relic Warning: https://github.com/newrelic/newrelic-browser-agent/blob/main/docs/warning-codes.md#".concat(e),t)}r.d(t,{R:()=>n})},5284:(e,t,r)=>{"use strict";r.d(t,{t:()=>c,B:()=>s});var n=r(7836),i=r(6154);const o="newrelic";const a=new Set,s={};function c(e,t){const r=n.ee.get(t);s[t]??={},e&&"object"==typeof e&&(a.has(t)||(r.emit("rumresp",[e]),s[t]=e,a.add(t),function(e={}){try{i.gm.dispatchEvent(new CustomEvent(o,{detail:e}))}catch(e){}}({loaded:!0})))}},8990:(e,t,r)=>{"use strict";r.d(t,{I:()=>i});var n=Object.prototype.hasOwnProperty;function i(e,t,r){if(n.call(e,t))return e[t];var i=r();if(Object.defineProperty&&Object.keys)try{return Object.defineProperty(e,t,{value:i,writable:!0,enumerable:!1}),i}catch(e){}return e[t]=i,i}},6389:(e,t,r)=>{"use strict";function n(e,t=500,r={}){const n=r?.leading||!1;let i;return(...r)=>{n&&void 0===i&&(e.apply(this,r),i=setTimeout((()=>{i=clearTimeout(i)}),t)),n||(clearTimeout(i),i=setTimeout((()=>{e.apply(this,r)}),t))}}function i(e){let t=!1;return(...r)=>{t||(t=!0,e.apply(this,r))}}r.d(t,{J:()=>i,s:()=>n})},3304:(e,t,r)=>{"use strict";r.d(t,{A:()=>o});var n=r(7836);const i=()=>{const e=new WeakSet;return(t,r)=>{if("object"==typeof r&&null!==r){if(e.has(r))return;e.add(r)}return r}};function o(e){try{return JSON.stringify(e,i())??""}catch(e){try{n.ee.emit("internal-error",[e])}catch(e){}return""}}},5289:(e,t,r)=>{"use strict";r.d(t,{GG:()=>o,sB:()=>a});var n=r(3878);function i(){return"undefined"==typeof document||"complete"===document.readyState}function o(e,t){if(i())return e();(0,n.sp)("load",e,t)}function a(e){if(i())return e();(0,n.DD)("DOMContentLoaded",e)}},384:(e,t,r)=>{"use strict";r.d(t,{NT:()=>o,US:()=>u,Zm:()=>a,bQ:()=>c,dV:()=>s,nY:()=>d,pV:()=>l});var n=r(6154),i=r(1863);const o={beacon:"bam.nr-data.net",errorBeacon:"bam.nr-data.net"};function a(){return n.gm.NREUM||(n.gm.NREUM={}),void 0===n.gm.newrelic&&(n.gm.newrelic=n.gm.NREUM),n.gm.NREUM}function s(){let e=a();return e.o||(e.o={ST:n.gm.setTimeout,SI:n.gm.setImmediate,CT:n.gm.clearTimeout,XHR:n.gm.XMLHttpRequest,REQ:n.gm.Request,EV:n.gm.Event,PR:n.gm.Promise,MO:n.gm.MutationObserver,FETCH:n.gm.fetch,WS:n.gm.WebSocket}),e}function c(e,t){let r=a();r.initializedAgents??={},t.initializedAt={ms:(0,i.t)(),date:new Date},r.initializedAgents[e]=t}function d(e){let t=a();return t.initializedAgents?.[e]}function u(e,t){a()[e]=t}function l(){return function(){let e=a();const t=e.info||{};e.info={beacon:o.beacon,errorBeacon:o.errorBeacon,...t}}(),function(){let e=a();const t=e.init||{};e.init={...t}}(),s(),function(){let e=a();const t=e.loader_config||{};e.loader_config={...t}}(),a()}},2843:(e,t,r)=>{"use strict";r.d(t,{u:()=>i});var n=r(3878);function i(e,t=!1,r,i){(0,n.DD)("visibilitychange",(function(){if(t)return void("hidden"===document.visibilityState&&e());e(document.visibilityState)}),r,i)}},8139:(e,t,r)=>{"use strict";r.d(t,{u:()=>f});var n=r(7836),i=r(3434),o=r(8990),a=r(6154);const s={},c=a.gm.XMLHttpRequest,d="addEventListener",u="removeEventListener",l="nr@wrapped:".concat(n.P);function f(e){var t=function(e){return(e||n.ee).get("events")}(e);if(s[t.debugId]++)return t;s[t.debugId]=1;var r=(0,i.YM)(t,!0);function f(e){r.inPlace(e,[d,u],"-",g)}function g(e,t){return e[1]}return"getPrototypeOf"in Object&&(a.RI&&h(document,f),h(a.gm,f),h(c.prototype,f)),t.on(d+"-start",(function(e,t){var n=e[1];if(null!==n&&("function"==typeof n||"object"==typeof n)){var i=(0,o.I)(n,l,(function(){var e={object:function(){if("function"!=typeof n.handleEvent)return;return n.handleEvent.apply(n,arguments)},function:n}[typeof n];return e?r(e,"fn-",null,e.name||"anonymous"):n}));this.wrapped=e[1]=i}})),t.on(u+"-start",(function(e){e[1]=this.wrapped||e[1]})),t}function h(e,t,...r){let n=e;for(;"object"==typeof n&&!Object.prototype.hasOwnProperty.call(n,d);)n=Object.getPrototypeOf(n);n&&t(n,...r)}},3434:(e,t,r)=>{"use strict";r.d(t,{YM:()=>c});var n=r(7836),i=r(5607);const o="nr@original:".concat(i.W);var a=Object.prototype.hasOwnProperty,s=!1;function c(e,t){return e||(e=n.ee),r.inPlace=function(e,t,n,i,o){n||(n="");const a="-"===n.charAt(0);for(let s=0;s<t.length;s++){const c=t[s],d=e[c];u(d)||(e[c]=r(d,a?c+n:n,i,c,o))}},r.flag=o,r;function r(t,r,n,s,c){return u(t)?t:(r||(r=""),nrWrapper[o]=t,function(e,t,r){if(Object.defineProperty&&Object.keys)try{return Object.keys(e).forEach((function(r){Object.defineProperty(t,r,{get:function(){return e[r]},set:function(t){return e[r]=t,t}})})),t}catch(e){d([e],r)}for(var n in e)a.call(e,n)&&(t[n]=e[n])}(t,nrWrapper,e),nrWrapper);function nrWrapper(){var o,a,u,l;try{a=this,o=[...arguments],u="function"==typeof n?n(o,a):n||{}}catch(t){d([t,"",[o,a,s],u],e)}i(r+"start",[o,a,s],u,c);try{return l=t.apply(a,o)}catch(e){throw i(r+"err",[o,a,e],u,c),e}finally{i(r+"end",[o,a,l],u,c)}}}function i(r,n,i,o){if(!s||t){var a=s;s=!0;try{e.emit(r,n,i,t,o)}catch(t){d([t,r,n,i],e)}s=a}}}function d(e,t){t||(t=n.ee);try{t.emit("internal-error",e)}catch(e){}}function u(e){return!(e&&"function"==typeof e&&e.apply&&!e[o])}},9300:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.ajax},3333:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,Zp:()=>i,mq:()=>s,nf:()=>a,qN:()=>o});const n=r(860).K7.genericEvents,i=["auxclick","click","copy","keydown","paste","scrollend"],o=["focus","blur"],a=4,s=1e3},6774:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.jserrors},993:(e,t,r)=>{"use strict";r.d(t,{ET:()=>o,TZ:()=>a,p_:()=>i});var n=r(860);const i={ERROR:"ERROR",WARN:"WARN",INFO:"INFO",DEBUG:"DEBUG",TRACE:"TRACE"},o="log",a=n.K7.logging},3785:(e,t,r)=>{"use strict";r.d(t,{R:()=>c,b:()=>d});var n=r(9908),i=r(1863),o=r(860),a=r(3969),s=r(993);function c(e,t,r={},c=s.p_.INFO){(0,n.p)(a.xV,["API/logging/".concat(c.toLowerCase(),"/called")],void 0,o.K7.metrics,e),(0,n.p)(s.ET,[(0,i.t)(),t,r,c],void 0,o.K7.logging,e)}function d(e){return"string"==typeof e&&Object.values(s.p_).some((t=>t===e.toUpperCase().trim()))}},3969:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,XG:()=>s,rs:()=>i,xV:()=>a,z_:()=>o});const n=r(860).K7.metrics,i="sm",o="cm",a="storeSupportabilityMetrics",s="storeEventMetrics"},6630:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewEvent},782:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewTiming},6344:(e,t,r)=>{"use strict";r.d(t,{BB:()=>u,G4:()=>o,Qb:()=>l,TZ:()=>i,Ug:()=>a,_s:()=>s,bc:()=>d,yP:()=>c});var n=r(2614);const i=r(860).K7.sessionReplay,o={RECORD:"recordReplay",PAUSE:"pauseReplay",REPLAY_RUNNING:"replayRunning",ERROR_DURING_REPLAY:"errorDuringReplay"},a=.12,s={DomContentLoaded:0,Load:1,FullSnapshot:2,IncrementalSnapshot:3,Meta:4,Custom:5},c={[n.g.ERROR]:15e3,[n.g.FULL]:3e5,[n.g.OFF]:0},d={RESET:{message:"Session was reset",sm:"Reset"},IMPORT:{message:"Recorder failed to import",sm:"Import"},TOO_MANY:{message:"429: Too Many Requests",sm:"Too-Many"},TOO_BIG:{message:"Payload was too large",sm:"Too-Big"},CROSS_TAB:{message:"Session Entity was set to OFF on another tab",sm:"Cross-Tab"},ENTITLEMENTS:{message:"Session Replay is not allowed and will not be started",sm:"Entitlement"}},u=5e3,l={API:"api"}},5270:(e,t,r)=>{"use strict";r.d(t,{Aw:()=>c,CT:()=>d,SR:()=>s});var n=r(384),i=r(9417),o=r(7767),a=r(6154);function s(e){return!!(0,n.dV)().o.MO&&(0,o.V)(e)&&!0===(0,i.gD)(e,"session_trace.enabled")}function c(e){return!0===(0,i.gD)(e,"session_replay.preload")&&s(e)}function d(e,t){const r=t.correctAbsoluteTimestamp(e);return{originalTimestamp:e,correctedTimestamp:r,timestampDiff:e-r,originTime:a.WN,correctedOriginTime:t.correctedOriginTime,originTimeDiff:Math.floor(a.WN-t.correctedOriginTime)}}},3738:(e,t,r)=>{"use strict";r.d(t,{He:()=>i,Kp:()=>s,Lc:()=>d,Rz:()=>u,TZ:()=>n,bD:()=>o,d3:()=>a,jx:()=>l,uP:()=>c});const n=r(860).K7.sessionTrace,i="bstResource",o="resource",a="-start",s="-end",c="fn"+a,d="fn"+s,u="pushState",l=1e3},4234:(e,t,r)=>{"use strict";r.d(t,{W:()=>o});var n=r(7836),i=r(1687);class o{constructor(e,t){this.agentIdentifier=e,this.ee=n.ee.get(e),this.featureName=t,this.blocked=!1}deregisterDrain(){(0,i.x3)(this.agentIdentifier,this.featureName)}}},7767:(e,t,r)=>{"use strict";r.d(t,{V:()=>o});var n=r(9417),i=r(6154);const o=e=>i.RI&&!0===(0,n.gD)(e,"privacy.cookies_enabled")},425:(e,t,r)=>{"use strict";r.d(t,{j:()=>P});var n=r(860),i=r(2555),o=r(3371),a=r(9908),s=r(7836),c=r(1687),d=r(5289),u=r(6154),l=r(944),f=r(3969),h=r(384),g=r(6344);const p=["setErrorHandler","finished","addToTrace","addRelease","addPageAction","setCurrentRouteName","setPageViewName","setCustomAttribute","interaction","noticeError","setUserId","setApplicationVersion","start",g.G4.RECORD,g.G4.PAUSE,"log","wrapLogger"],m=["setErrorHandler","finished","addToTrace","addRelease"];var v=r(1863),b=r(2614),y=r(993),R=r(3785),x=r(2646),w=r(3434);function T(e,t,r,n){if("object"!=typeof t||!t||"string"!=typeof r||!r||"function"!=typeof t[r])return(0,l.R)(29);const i=function(e){return(e||s.ee).get("logger")}(e),o=(0,w.YM)(i),a=new x.y(s.P);return a.level=n.level,a.customAttributes=n.customAttributes,o.inPlace(t,[r],"wrap-logger-",a),i}function A(){const e=(0,h.pV)();p.forEach((t=>{e[t]=(...r)=>function(t,...r){let n=[];return Object.values(e.initializedAgents).forEach((e=>{e&&e.api?e.exposed&&e.api[t]&&n.push(e.api[t](...r)):(0,l.R)(38,t)})),n.length>1?n:n[0]}(t,...r)}))}const E={};var S=r(9417),_=r(5603),O=r(5284);const N=e=>{const t=e.startsWith("http");e+="/",r.p=t?e:"https://"+e};let I=!1;function P(e,t={},p,x){let{init:w,info:P,loader_config:j,runtime:C={},exposed:k=!0}=t;C.loaderType=p;const H=(0,h.pV)();P||(w=H.init,P=H.info,j=H.loader_config),(0,S.xN)(e.agentIdentifier,w||{}),(0,_.a)(e.agentIdentifier,j||{}),P.jsAttributes??={},u.bv&&(P.jsAttributes.isWorker=!0),(0,i.x1)(e.agentIdentifier,P);const D=(0,S.D0)(e.agentIdentifier),L=[P.beacon,P.errorBeacon];I||(D.proxy.assets&&(N(D.proxy.assets),L.push(D.proxy.assets)),D.proxy.beacon&&L.push(D.proxy.beacon),A(),(0,h.US)("activatedFeatures",O.B),e.runSoftNavOverSpa&&=!0===D.soft_navigations.enabled&&D.feature_flags.includes("soft_nav")),C.denyList=[...D.ajax.deny_list||[],...D.ajax.block_internal?L:[]],C.ptid=e.agentIdentifier,(0,o.V)(e.agentIdentifier,C),e.ee=s.ee.get(e.agentIdentifier),void 0===e.api&&(e.api=function(e,t,h=!1){t||(0,c.Ak)(e,"api");const p={};var x=s.ee.get(e),w=x.get("tracer");E[e]=b.g.OFF,x.on(g.G4.REPLAY_RUNNING,(t=>{E[e]=t}));var A="api-",S=A+"ixn-";function _(t,r,n,o){const a=(0,i.Vp)(e);return null===r?delete a.jsAttributes[t]:(0,i.x1)(e,{...a,jsAttributes:{...a.jsAttributes,[t]:r}}),I(A,n,!0,o||null===r?"session":void 0)(t,r)}function O(){}p.log=function(e,{customAttributes:t={},level:r=y.p_.INFO}={}){(0,a.p)(f.xV,["API/log/called"],void 0,n.K7.metrics,x),(0,R.R)(x,e,t,r)},p.wrapLogger=(e,t,{customAttributes:r={},level:i=y.p_.INFO}={})=>{(0,a.p)(f.xV,["API/wrapLogger/called"],void 0,n.K7.metrics,x),T(x,e,t,{customAttributes:r,level:i})},m.forEach((e=>{p[e]=I(A,e,!0,"api")})),p.addPageAction=I(A,"addPageAction",!0,n.K7.genericEvents),p.setPageViewName=function(t,r){if("string"==typeof t)return"/"!==t.charAt(0)&&(t="/"+t),(0,o.f)(e).customTransaction=(r||"http://custom.transaction")+t,I(A,"setPageViewName",!0)()},p.setCustomAttribute=function(e,t,r=!1){if("string"==typeof e){if(["string","number","boolean"].includes(typeof t)||null===t)return _(e,t,"setCustomAttribute",r);(0,l.R)(40,typeof t)}else(0,l.R)(39,typeof e)},p.setUserId=function(e){if("string"==typeof e||null===e)return _("enduser.id",e,"setUserId",!0);(0,l.R)(41,typeof e)},p.setApplicationVersion=function(e){if("string"==typeof e||null===e)return _("application.version",e,"setApplicationVersion",!1);(0,l.R)(42,typeof e)},p.start=()=>{try{(0,a.p)(f.xV,["API/start/called"],void 0,n.K7.metrics,x),x.emit("manual-start-all")}catch(e){(0,l.R)(23,e)}},p[g.G4.RECORD]=function(){(0,a.p)(f.xV,["API/recordReplay/called"],void 0,n.K7.metrics,x),(0,a.p)(g.G4.RECORD,[],void 0,n.K7.sessionReplay,x)},p[g.G4.PAUSE]=function(){(0,a.p)(f.xV,["API/pauseReplay/called"],void 0,n.K7.metrics,x),(0,a.p)(g.G4.PAUSE,[],void 0,n.K7.sessionReplay,x)},p.interaction=function(e){return(new O).get("object"==typeof e?e:{})};const N=O.prototype={createTracer:function(e,t){var r={},i=this,o="function"==typeof t;return(0,a.p)(f.xV,["API/createTracer/called"],void 0,n.K7.metrics,x),h||(0,a.p)(S+"tracer",[(0,v.t)(),e,r],i,n.K7.spa,x),function(){if(w.emit((o?"":"no-")+"fn-start",[(0,v.t)(),i,o],r),o)try{return t.apply(this,arguments)}catch(e){const t="string"==typeof e?new Error(e):e;throw w.emit("fn-err",[arguments,this,t],r),t}finally{w.emit("fn-end",[(0,v.t)()],r)}}}};function I(e,t,r,i){return function(){return(0,a.p)(f.xV,["API/"+t+"/called"],void 0,n.K7.metrics,x),i&&(0,a.p)(e+t,[(0,v.t)(),...arguments],r?null:this,i,x),r?void 0:this}}function P(){r.e(891).then(r.bind(r,8778)).then((({setAPI:t})=>{t(e),(0,c.Ze)(e,"api")})).catch((e=>{(0,l.R)(27,e),x.abort()}))}return["actionText","setName","setAttribute","save","ignore","onEnd","getContext","end","get"].forEach((e=>{N[e]=I(S,e,void 0,h?n.K7.softNav:n.K7.spa)})),p.setCurrentRouteName=h?I(S,"routeName",void 0,n.K7.softNav):I(A,"routeName",!0,n.K7.spa),p.noticeError=function(t,r){"string"==typeof t&&(t=new Error(t)),(0,a.p)(f.xV,["API/noticeError/called"],void 0,n.K7.metrics,x),(0,a.p)("err",[t,(0,v.t)(),!1,r,!!E[e]],void 0,n.K7.jserrors,x)},u.RI?(0,d.GG)((()=>P()),!0):P(),p}(e.agentIdentifier,x,e.runSoftNavOverSpa)),void 0===e.exposed&&(e.exposed=k),I=!0}},8374:(e,t,r)=>{r.nc=(()=>{try{return document?.currentScript?.nonce}catch(e){}return""})()},860:(e,t,r)=>{"use strict";r.d(t,{$J:()=>o,K7:()=>n,P3:()=>i});const n={ajax:"ajax",genericEvents:"generic_events",jserrors:"jserrors",logging:"logging",metrics:"metrics",pageAction:"page_action",pageViewEvent:"page_view_event",pageViewTiming:"page_view_timing",sessionReplay:"session_replay",sessionTrace:"session_trace",softNav:"soft_navigations",spa:"spa"},i={[n.pageViewEvent]:1,[n.pageViewTiming]:2,[n.metrics]:3,[n.jserrors]:4,[n.spa]:5,[n.ajax]:6,[n.sessionTrace]:7,[n.softNav]:8,[n.sessionReplay]:9,[n.logging]:10,[n.genericEvents]:11},o={[n.pageViewTiming]:"events",[n.ajax]:"events",[n.spa]:"events",[n.softNav]:"events",[n.metrics]:"jserrors",[n.jserrors]:"jserrors",[n.sessionTrace]:"browser/blobs",[n.sessionReplay]:"browser/blobs",[n.logging]:"browser/logs",[n.genericEvents]:"ins"}}},n={};function i(e){var t=n[e];if(void 0!==t)return t.exports;var o=n[e]={exports:{}};return r[e](o,o.exports,i),o.exports}i.m=r,i.d=(e,t)=>{for(var r in t)i.o(t,r)&&!i.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})},i.f={},i.e=e=>Promise.all(Object.keys(i.f).reduce(((t,r)=>(i.f[r](e,t),t)),[])),i.u=e=>({95:"nr-full-compressor",222:"nr-full-recorder",891:"nr-full"}[e]+"-1.274.0.min.js"),i.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),e={},t="NRBA-1.274.0.PROD:",i.l=(r,n,o,a)=>{if(e[r])e[r].push(n);else{var s,c;if(void 0!==o)for(var d=document.getElementsByTagName("script"),u=0;u<d.length;u++){var l=d[u];if(l.getAttribute("src")==r||l.getAttribute("data-webpack")==t+o){s=l;break}}if(!s){c=!0;var f={891:"sha512-Sx2xJQrHp2m/Ngn/ZcfBCUwNr2Xy/C5urYtWpfm3bWpil4spXOQGTtNwIfF5HvPGioGASn9QTyE4Z+zC7r7wcg==",222:"sha512-hMte3OWgwwYeisSiD7WCIx/6tT16zLaPjag9uF4tIZp7ybOvrJKbeyzhe4fz1tDbkdcdOMm8dvgPPLBatSAGeA==",95:"sha512-MPaT9dkHv16XzwEUVZPyqpN1do/Er1XFAZoIAPYWylmv+iGIThqN+GwQq27pUyAX7sNXVJQVZezH96p53Ks3Pg=="};(s=document.createElement("script")).charset="utf-8",s.timeout=120,i.nc&&s.setAttribute("nonce",i.nc),s.setAttribute("data-webpack",t+o),s.src=r,0!==s.src.indexOf(window.location.origin+"/")&&(s.crossOrigin="anonymous"),f[a]&&(s.integrity=f[a])}e[r]=[n];var h=(t,n)=>{s.onerror=s.onload=null,clearTimeout(g);var i=e[r];if(delete e[r],s.parentNode&&s.parentNode.removeChild(s),i&&i.forEach((e=>e(n))),t)return t(n)},g=setTimeout(h.bind(null,void 0,{type:"timeout",target:s}),12e4);s.onerror=h.bind(null,s.onerror),s.onload=h.bind(null,s.onload),c&&document.head.appendChild(s)}},i.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})},i.p="https://js-agent.newrelic.com/",(()=>{var e={959:0,85:0};i.f.j=(t,r)=>{var n=i.o(e,t)?e[t]:void 0;if(0!==n)if(n)r.push(n[2]);else{var o=new Promise(((r,i)=>n=e[t]=[r,i]));r.push(n[2]=o);var a=i.p+i.u(t),s=new Error;i.l(a,(r=>{if(i.o(e,t)&&(0!==(n=e[t])&&(e[t]=void 0),n)){var o=r&&("load"===r.type?"missing":r.type),a=r&&r.target&&r.target.src;s.message="Loading chunk "+t+" failed.\n("+o+": "+a+")",s.name="ChunkLoadError",s.type=o,s.request=a,n[1](s)}}),"chunk-"+t,t)}};var t=(t,r)=>{var n,o,[a,s,c]=r,d=0;if(a.some((t=>0!==e[t]))){for(n in s)i.o(s,n)&&(i.m[n]=s[n]);if(c)c(i)}for(t&&t(r);d<a.length;d++)o=a[d],i.o(e,o)&&e[o]&&e[o][0](),e[o]=0},r=self["webpackChunk:NRBA-1.274.0.PROD"]=self["webpackChunk:NRBA-1.274.0.PROD"]||[];r.forEach(t.bind(null,0)),r.push=t.bind(null,r.push.bind(r))})(),(()=>{"use strict";i(8374);var e=i(944),t=i(6344),r=i(9566);class n{agentIdentifier;constructor(e=(0,r.LA)(16)){this.agentIdentifier=e}#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}addPageAction(e,t){return this.#e("addPageAction",e,t)}setPageViewName(e,t){return this.#e("setPageViewName",e,t)}setCustomAttribute(e,t,r){return this.#e("setCustomAttribute",e,t,r)}noticeError(e,t){return this.#e("noticeError",e,t)}setUserId(e){return this.#e("setUserId",e)}setApplicationVersion(e){return this.#e("setApplicationVersion",e)}setErrorHandler(e){return this.#e("setErrorHandler",e)}addRelease(e,t){return this.#e("addRelease",e,t)}log(e,t){return this.#e("log",e,t)}}class o extends n{#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}start(){return this.#e("start")}finished(e){return this.#e("finished",e)}recordReplay(){return this.#e(t.G4.RECORD)}pauseReplay(){return this.#e(t.G4.PAUSE)}addToTrace(e){return this.#e("addToTrace",e)}setCurrentRouteName(e){return this.#e("setCurrentRouteName",e)}interaction(){return this.#e("interaction")}wrapLogger(e,t,r){return this.#e("wrapLogger",e,t,r)}}var a=i(860),s=i(9417);const c=Object.values(a.K7);function d(e){const t={};return c.forEach((r=>{t[r]=function(e,t){return!0===(0,s.gD)(t,"".concat(e,".enabled"))}(r,e)})),t}var u=i(425);var l=i(1687),f=i(4234),h=i(5289),g=i(6154),p=i(5270),m=i(7767),v=i(6389);class b extends f.W{constructor(e,t,r=!0){super(e.agentIdentifier,t),this.auto=r,this.abortHandler=void 0,this.featAggregate=void 0,this.onAggregateImported=void 0,!1===e.init[this.featureName].autoStart&&(this.auto=!1),this.auto?(0,l.Ak)(e.agentIdentifier,t):this.ee.on("manual-start-all",(0,v.J)((()=>{(0,l.Ak)(e.agentIdentifier,this.featureName),this.auto=!0,this.importAggregator(e)})))}importAggregator(t,r={}){if(this.featAggregate||!this.auto)return;let n;this.onAggregateImported=new Promise((e=>{n=e}));const o=async()=>{let o;try{if((0,m.V)(this.agentIdentifier)){const{setupAgentSession:e}=await i.e(891).then(i.bind(i,6526));o=e(t)}}catch(t){(0,e.R)(20,t),this.ee.emit("internal-error",[t]),this.featureName===a.K7.sessionReplay&&this.abortHandler?.()}try{if(t.sharedAggregator)await t.sharedAggregator;else{t.sharedAggregator=i.e(891).then(i.bind(i,9337));const{EventAggregator:e}=await t.sharedAggregator;t.sharedAggregator=new e}if(!this.#t(this.featureName,o))return(0,l.Ze)(this.agentIdentifier,this.featureName),void n(!1);const{lazyFeatureLoader:e}=await i.e(891).then(i.bind(i,6103)),{Aggregate:a}=await e(this.featureName,"aggregate");this.featAggregate=new a(t,r),n(!0)}catch(t){(0,e.R)(34,t),this.abortHandler?.(),(0,l.Ze)(this.agentIdentifier,this.featureName,!0),n(!1),this.ee&&this.ee.abort()}};g.RI?(0,h.GG)((()=>o()),!0):o()}#t(e,t){switch(e){case a.K7.sessionReplay:return(0,p.SR)(this.agentIdentifier)&&!!t;case a.K7.sessionTrace:return!!t;default:return!0}}}var y=i(6630);class R extends b{static featureName=y.T;constructor(e,t=!0){super(e,y.T,t),this.importAggregator(e)}}var x=i(384);var w=i(9908),T=i(2843),A=i(3878),E=i(782),S=i(1863);class _ extends b{static featureName=E.T;constructor(e,t=!0){super(e,E.T,t),g.RI&&((0,T.u)((()=>(0,w.p)("docHidden",[(0,S.t)()],void 0,E.T,this.ee)),!0),(0,A.sp)("pagehide",(()=>(0,w.p)("winPagehide",[(0,S.t)()],void 0,E.T,this.ee))),this.importAggregator(e))}}var O=i(3969);class N extends b{static featureName=O.TZ;constructor(e,t=!0){super(e,O.TZ,t),this.importAggregator(e)}}var I=i(6774),P=i(3304);class j{constructor(e,t,r,n,i){this.name="UncaughtError",this.message="string"==typeof e?e:(0,P.A)(e),this.sourceURL=t,this.line=r,this.column=n,this.__newrelic=i}}function C(e){return D(e)?e:new j(void 0!==e?.message?e.message:e,e?.filename||e?.sourceURL,e?.lineno||e?.line,e?.colno||e?.col,e?.__newrelic)}function k(e){const t="Unhandled Promise Rejection";if(!e?.reason)return;if(D(e.reason))try{return e.reason.message=t+": "+e.reason.message,C(e.reason)}catch(t){return C(e.reason)}const r=C(e.reason);return r.message=t+": "+r?.message,r}function H(e){if(e.error instanceof SyntaxError&&!/:\d+$/.test(e.error.stack?.trim())){const t=new j(e.message,e.filename,e.lineno,e.colno,e.error.__newrelic);return t.name=SyntaxError.name,t}return D(e.error)?e.error:C(e)}function D(e){return e instanceof Error&&!!e.stack}class L extends b{static featureName=I.T;#r=!1;constructor(e,r=!0){super(e,I.T,r);try{this.removeOnAbort=new AbortController}catch(e){}this.ee.on("internal-error",(e=>{this.abortHandler&&(0,w.p)("ierr",[C(e),(0,S.t)(),!0,{},this.#r],void 0,this.featureName,this.ee)})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.#r=e})),g.gm.addEventListener("unhandledrejection",(e=>{this.abortHandler&&(0,w.p)("err",[k(e),(0,S.t)(),!1,{unhandledPromiseRejection:1},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),g.gm.addEventListener("error",(e=>{this.abortHandler&&(0,w.p)("err",[H(e),(0,S.t)(),!1,{},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var K=i(8990);let M=1;const U="nr@id";function V(e){const t=typeof e;return!e||"object"!==t&&"function"!==t?-1:e===g.gm?0:(0,K.I)(e,U,(function(){return M++}))}function G(e){if("string"==typeof e&&e.length)return e.length;if("object"==typeof e){if("undefined"!=typeof ArrayBuffer&&e instanceof ArrayBuffer&&e.byteLength)return e.byteLength;if("undefined"!=typeof Blob&&e instanceof Blob&&e.size)return e.size;if(!("undefined"!=typeof FormData&&e instanceof FormData))try{return(0,P.A)(e).length}catch(e){return}}}var F=i(8139),B=i(7836),W=i(3434);const z={},q=["open","send"];function Z(t){var r=t||B.ee;const n=function(e){return(e||B.ee).get("xhr")}(r);if(z[n.debugId]++)return n;z[n.debugId]=1,(0,F.u)(r);var i=(0,W.YM)(n),o=g.gm.XMLHttpRequest,a=g.gm.MutationObserver,s=g.gm.Promise,c=g.gm.setInterval,d="readystatechange",u=["onload","onerror","onabort","onloadstart","onloadend","onprogress","ontimeout"],l=[],f=g.gm.XMLHttpRequest=function(t){const r=new o(t),a=n.context(r);try{n.emit("new-xhr",[r],a),r.addEventListener(d,(s=a,function(){var e=this;e.readyState>3&&!s.resolved&&(s.resolved=!0,n.emit("xhr-resolved",[],e)),i.inPlace(e,u,"fn-",y)}),(0,A.jT)(!1))}catch(t){(0,e.R)(15,t);try{n.emit("internal-error",[t])}catch(e){}}var s;return r};function h(e,t){i.inPlace(t,["onreadystatechange"],"fn-",y)}if(function(e,t){for(var r in e)t[r]=e[r]}(o,f),f.prototype=o.prototype,i.inPlace(f.prototype,q,"-xhr-",y),n.on("send-xhr-start",(function(e,t){h(e,t),function(e){l.push(e),a&&(p?p.then(b):c?c(b):(m=-m,v.data=m))}(t)})),n.on("open-xhr-start",h),a){var p=s&&s.resolve();if(!c&&!s){var m=1,v=document.createTextNode(m);new a(b).observe(v,{characterData:!0})}}else r.on("fn-end",(function(e){e[0]&&e[0].type===d||b()}));function b(){for(var e=0;e<l.length;e++)h(0,l[e]);l.length&&(l=[])}function y(e,t){return t}return n}var Y="fetch-",X=Y+"body-",Q=["arrayBuffer","blob","json","text","formData"],J=g.gm.Request,ee=g.gm.Response,te="prototype";const re={};function ne(e){const t=function(e){return(e||B.ee).get("fetch")}(e);if(!(J&&ee&&g.gm.fetch))return t;if(re[t.debugId]++)return t;function r(e,r,n){var i=e[r];"function"==typeof i&&(e[r]=function(){var e,r=[...arguments],o={};t.emit(n+"before-start",[r],o),o[B.P]&&o[B.P].dt&&(e=o[B.P].dt);var a=i.apply(this,r);return t.emit(n+"start",[r,e],a),a.then((function(e){return t.emit(n+"end",[null,e],a),e}),(function(e){throw t.emit(n+"end",[e],a),e}))})}return re[t.debugId]=1,Q.forEach((e=>{r(J[te],e,X),r(ee[te],e,X)})),r(g.gm,"fetch",Y),t.on(Y+"end",(function(e,r){var n=this;if(r){var i=r.headers.get("content-length");null!==i&&(n.rxSize=i),t.emit(Y+"done",[null,r],n)}else t.emit(Y+"done",[e],n)})),t}var ie=i(7485),oe=i(5603);class ae{constructor(e){this.agentIdentifier=e}generateTracePayload(e){if(!this.shouldGenerateTrace(e))return null;var t=(0,oe.o)(this.agentIdentifier);if(!t)return null;var n=(t.accountID||"").toString()||null,i=(t.agentID||"").toString()||null,o=(t.trustKey||"").toString()||null;if(!n||!i)return null;var a=(0,r.ZF)(),s=(0,r.el)(),c=Date.now(),d={spanId:a,traceId:s,timestamp:c};return(e.sameOrigin||this.isAllowedOrigin(e)&&this.useTraceContextHeadersForCors())&&(d.traceContextParentHeader=this.generateTraceContextParentHeader(a,s),d.traceContextStateHeader=this.generateTraceContextStateHeader(a,c,n,i,o)),(e.sameOrigin&&!this.excludeNewrelicHeader()||!e.sameOrigin&&this.isAllowedOrigin(e)&&this.useNewrelicHeaderForCors())&&(d.newrelicHeader=this.generateTraceHeader(a,s,c,n,i,o)),d}generateTraceContextParentHeader(e,t){return"00-"+t+"-"+e+"-01"}generateTraceContextStateHeader(e,t,r,n,i){return i+"@nr=0-1-"+r+"-"+n+"-"+e+"----"+t}generateTraceHeader(e,t,r,n,i,o){if(!("function"==typeof g.gm?.btoa))return null;var a={v:[0,1],d:{ty:"Browser",ac:n,ap:i,id:e,tr:t,ti:r}};return o&&n!==o&&(a.d.tk=o),btoa((0,P.A)(a))}shouldGenerateTrace(e){return this.isDtEnabled()&&this.isAllowedOrigin(e)}isAllowedOrigin(e){var t=!1,r={};if((0,s.gD)(this.agentIdentifier,"distributed_tracing")&&(r=(0,s.D0)(this.agentIdentifier).distributed_tracing),e.sameOrigin)t=!0;else if(r.allowed_origins instanceof Array)for(var n=0;n<r.allowed_origins.length;n++){var i=(0,ie.D)(r.allowed_origins[n]);if(e.hostname===i.hostname&&e.protocol===i.protocol&&e.port===i.port){t=!0;break}}return t}isDtEnabled(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.enabled}excludeNewrelicHeader(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.exclude_newrelic_header}useNewrelicHeaderForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!1!==e.cors_use_newrelic_header}useTraceContextHeadersForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.cors_use_tracecontext_headers}}var se=i(9300),ce=i(7295),de=["load","error","abort","timeout"],ue=de.length,le=(0,x.dV)().o.REQ,fe=(0,x.dV)().o.XHR;class he extends b{static featureName=se.T;constructor(e,t=!0){super(e,se.T,t),this.dt=new ae(e.agentIdentifier),this.handler=(e,t,r,n)=>(0,w.p)(e,t,r,n,this.ee);try{const e={xmlhttprequest:"xhr",fetch:"fetch",beacon:"beacon"};g.gm?.performance?.getEntriesByType("resource").forEach((t=>{if(t.initiatorType in e&&0!==t.responseStatus){const r={status:t.responseStatus},n={rxSize:t.transferSize,duration:Math.floor(t.duration),cbTime:0};ge(r,t.name),this.handler("xhr",[r,n,t.startTime,t.responseEnd,e[t.initiatorType]],void 0,a.K7.ajax)}}))}catch(e){}ne(this.ee),Z(this.ee),function(e,t,r,n){function i(e){var t=this;t.totalCbs=0,t.called=0,t.cbTime=0,t.end=x,t.ended=!1,t.xhrGuids={},t.lastSize=null,t.loadCaptureCalled=!1,t.params=this.params||{},t.metrics=this.metrics||{},e.addEventListener("load",(function(r){T(t,e)}),(0,A.jT)(!1)),g.lR||e.addEventListener("progress",(function(e){t.lastSize=e.loaded}),(0,A.jT)(!1))}function o(e){this.params={method:e[0]},ge(this,e[1]),this.metrics={}}function s(t,r){e.loader_config.xpid&&this.sameOrigin&&r.setRequestHeader("X-NewRelic-ID",e.loader_config.xpid);var i=n.generateTracePayload(this.parsedOrigin);if(i){var o=!1;i.newrelicHeader&&(r.setRequestHeader("newrelic",i.newrelicHeader),o=!0),i.traceContextParentHeader&&(r.setRequestHeader("traceparent",i.traceContextParentHeader),i.traceContextStateHeader&&r.setRequestHeader("tracestate",i.traceContextStateHeader),o=!0),o&&(this.dt=i)}}function c(e,r){var n=this.metrics,i=e[0],o=this;if(n&&i){var a=G(i);a&&(n.txSize=a)}this.startTime=(0,S.t)(),this.body=i,this.listener=function(e){try{"abort"!==e.type||o.loadCaptureCalled||(o.params.aborted=!0),("load"!==e.type||o.called===o.totalCbs&&(o.onloadCalled||"function"!=typeof r.onload)&&"function"==typeof o.end)&&o.end(r)}catch(e){try{t.emit("internal-error",[e])}catch(e){}}};for(var s=0;s<ue;s++)r.addEventListener(de[s],this.listener,(0,A.jT)(!1))}function d(e,t,r){this.cbTime+=e,t?this.onloadCalled=!0:this.called+=1,this.called!==this.totalCbs||!this.onloadCalled&&"function"==typeof r.onload||"function"!=typeof this.end||this.end(r)}function u(e,t){var r=""+V(e)+!!t;this.xhrGuids&&!this.xhrGuids[r]&&(this.xhrGuids[r]=!0,this.totalCbs+=1)}function l(e,t){var r=""+V(e)+!!t;this.xhrGuids&&this.xhrGuids[r]&&(delete this.xhrGuids[r],this.totalCbs-=1)}function f(){this.endTime=(0,S.t)()}function h(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-added",[e[1],e[2]],r)}function p(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-removed",[e[1],e[2]],r)}function m(e,t,r){t instanceof fe&&("onload"===r&&(this.onload=!0),("load"===(e[0]&&e[0].type)||this.onload)&&(this.xhrCbStart=(0,S.t)()))}function v(e,r){this.xhrCbStart&&t.emit("xhr-cb-time",[(0,S.t)()-this.xhrCbStart,this.onload,r],r)}function b(e){var t,r=e[1]||{};if("string"==typeof e[0]?0===(t=e[0]).length&&g.RI&&(t=""+g.gm.location.href):e[0]&&e[0].url?t=e[0].url:g.gm?.URL&&e[0]&&e[0]instanceof URL?t=e[0].href:"function"==typeof e[0].toString&&(t=e[0].toString()),"string"==typeof t&&0!==t.length){t&&(this.parsedOrigin=(0,ie.D)(t),this.sameOrigin=this.parsedOrigin.sameOrigin);var i=n.generateTracePayload(this.parsedOrigin);if(i&&(i.newrelicHeader||i.traceContextParentHeader))if(e[0]&&e[0].headers)s(e[0].headers,i)&&(this.dt=i);else{var o={};for(var a in r)o[a]=r[a];o.headers=new Headers(r.headers||{}),s(o.headers,i)&&(this.dt=i),e.length>1?e[1]=o:e.push(o)}}function s(e,t){var r=!1;return t.newrelicHeader&&(e.set("newrelic",t.newrelicHeader),r=!0),t.traceContextParentHeader&&(e.set("traceparent",t.traceContextParentHeader),t.traceContextStateHeader&&e.set("tracestate",t.traceContextStateHeader),r=!0),r}}function y(e,t){this.params={},this.metrics={},this.startTime=(0,S.t)(),this.dt=t,e.length>=1&&(this.target=e[0]),e.length>=2&&(this.opts=e[1]);var r,n=this.opts||{},i=this.target;"string"==typeof i?r=i:"object"==typeof i&&i instanceof le?r=i.url:g.gm?.URL&&"object"==typeof i&&i instanceof URL&&(r=i.href),ge(this,r);var o=(""+(i&&i instanceof le&&i.method||n.method||"GET")).toUpperCase();this.params.method=o,this.body=n.body,this.txSize=G(n.body)||0}function R(e,t){if(this.endTime=(0,S.t)(),this.params||(this.params={}),(0,ce.iW)(this.params))return;let n;this.params.status=t?t.status:0,"string"==typeof this.rxSize&&this.rxSize.length>0&&(n=+this.rxSize);const i={txSize:this.txSize,rxSize:n,duration:(0,S.t)()-this.startTime};r("xhr",[this.params,i,this.startTime,this.endTime,"fetch"],this,a.K7.ajax)}function x(e){const t=this.params,n=this.metrics;if(!this.ended){this.ended=!0;for(let t=0;t<ue;t++)e.removeEventListener(de[t],this.listener,!1);t.aborted||(0,ce.iW)(t)||(n.duration=(0,S.t)()-this.startTime,this.loadCazptureCalled||4!==e.readyState?null==t.status&&(t.status=0):T(this,e),n.cbTime=this.cbTime,r("xhr",[t,n,this.startTime,this.endTime,"xhr"],this,a.K7.ajax))}}function T(e,r){e.params.status=r.status;var n=function(e,t){var r=e.responseType;return"json"===r&&null!==t?t:"arraybuffer"===r||"blob"===r||"json"===r?G(e.response):"text"===r||""===r||void 0===r?G(e.responseText):void 0}(r,e.lastSize);if(n&&(e.metrics.rxSize=n),e.sameOrigin){var i=r.getResponseHeader("X-NewRelic-App-Data");i&&((0,w.p)(O.rs,["Ajax/CrossApplicationTracing/Header/Seen"],void 0,a.K7.metrics,t),e.params.cat=i.split(", ").pop())}e.loadCaptureCalled=!0}t.on("new-xhr",i),t.on("open-xhr-start",o),t.on("open-xhr-end",s),t.on("send-xhr-start",c),t.on("xhr-cb-time",d),t.on("xhr-load-added",u),t.on("xhr-load-removed",l),t.on("xhr-resolved",f),t.on("addEventListener-end",h),t.on("removeEventListener-end",p),t.on("fn-end",v),t.on("fetch-before-start",b),t.on("fetch-start",y),t.on("fn-start",m),t.on("fetch-done",R)}(e,this.ee,this.handler,this.dt),this.importAggregator(e)}}function ge(e,t){var r=(0,ie.D)(t),n=e.params||e;n.hostname=r.hostname,n.port=r.port,n.protocol=r.protocol,n.host=r.hostname+":"+r.port,n.pathname=r.pathname,e.parsedOrigin=r,e.sameOrigin=r.sameOrigin}const pe={},me=["pushState","replaceState"];function ve(e){const t=function(e){return(e||B.ee).get("history")}(e);return!g.RI||pe[t.debugId]++||(pe[t.debugId]=1,(0,W.YM)(t).inPlace(window.history,me,"-")),t}var be=i(3738);const{He:ye,bD:Re,d3:xe,Kp:we,TZ:Te,Lc:Ae,uP:Ee,Rz:Se}=be;class _e extends b{static featureName=Te;constructor(e,t=!0){super(e,Te,t);if(!(0,m.V)(this.agentIdentifier))return void this.deregisterDrain();const r=this.ee;let n;ve(r),this.eventsEE=(0,F.u)(r),this.eventsEE.on(Ee,(function(e,t){this.bstStart=(0,S.t)()})),this.eventsEE.on(Ae,(function(e,t){(0,w.p)("bst",[e[0],t,this.bstStart,(0,S.t)()],void 0,a.K7.sessionTrace,r)})),r.on(Se+xe,(function(e){this.time=(0,S.t)(),this.startPath=location.pathname+location.hash})),r.on(Se+we,(function(e){(0,w.p)("bstHist",[location.pathname+location.hash,this.startPath,this.time],void 0,a.K7.sessionTrace,r)}));try{n=new PerformanceObserver((e=>{const t=e.getEntries();(0,w.p)(ye,[t],void 0,a.K7.sessionTrace,r)})),n.observe({type:Re,buffered:!0})}catch(e){}this.importAggregator(e,{resourceObserver:n})}}var Oe=i(2614);class Ne extends b{static featureName=t.TZ;#i;#o;constructor(e,r=!0){let n;super(e,t.TZ,r),this.replayRunning=!1,this.#o=e;try{n=JSON.parse(localStorage.getItem("".concat(Oe.H3,"_").concat(Oe.uh)))}catch(e){}(0,p.SR)(e.agentIdentifier)&&this.ee.on(t.G4.RECORD,(()=>this.#a())),this.#s(n)?(this.#i=n?.sessionReplayMode,this.#c()):this.importAggregator(e),this.ee.on("err",(e=>{this.replayRunning&&(this.errorNoticed=!0,(0,w.p)(t.G4.ERROR_DURING_REPLAY,[e],void 0,this.featureName,this.ee))})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.replayRunning=e}))}#s(e){return e&&(e.sessionReplayMode===Oe.g.FULL||e.sessionReplayMode===Oe.g.ERROR)||(0,p.Aw)(this.agentIdentifier)}#d=!1;async#c(e){if(!this.#d){this.#d=!0;try{const{Recorder:t}=await Promise.all([i.e(891),i.e(222)]).then(i.bind(i,8589));this.recorder??=new t({mode:this.#i,agentIdentifier:this.agentIdentifier,trigger:e,ee:this.ee}),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording}catch(e){}this.importAggregator(this.#o,{recorder:this.recorder,errorNoticed:this.errorNoticed})}}#a(){this.featAggregate?this.featAggregate.mode!==Oe.g.FULL&&this.featAggregate.initializeRecording(Oe.g.FULL,!0):(this.#i=Oe.g.FULL,this.#c(t.Qb.API),this.recorder&&this.recorder.parent.mode!==Oe.g.FULL&&(this.recorder.parent.mode=Oe.g.FULL,this.recorder.stopRecording(),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording))}}var Ie=i(3333);class Pe extends b{static featureName=Ie.TZ;constructor(e,t=!0){super(e,Ie.TZ,t);const r=[e.init.page_action.enabled,e.init.performance.capture_marks,e.init.performance.capture_measures,e.init.user_actions.enabled];g.RI&&e.init.user_actions.enabled&&(Ie.Zp.forEach((e=>(0,A.sp)(e,(e=>(0,w.p)("ua",[e],void 0,this.featureName,this.ee)),!0))),Ie.qN.forEach((e=>(0,A.sp)(e,(e=>(0,w.p)("ua",[e],void 0,this.featureName,this.ee)))))),r.some((e=>e))?this.importAggregator(e):this.deregisterDrain()}}var je=i(993),Ce=i(3785);class ke extends b{static featureName=je.TZ;constructor(e,t=!0){super(e,je.TZ,t);const r=this.ee;this.ee.on("wrap-logger-end",(function([e]){const{level:t,customAttributes:n}=this;(0,Ce.R)(r,e,n,t)})),this.importAggregator(e)}}new class extends o{constructor(t,r){super(r),g.gm?(this.features={},(0,x.bQ)(this.agentIdentifier,this),this.desiredFeatures=new Set(t.features||[]),this.desiredFeatures.add(R),this.runSoftNavOverSpa=[...this.desiredFeatures].some((e=>e.featureName===a.K7.softNav)),(0,u.j)(this,t,t.loaderType||"agent"),this.run()):(0,e.R)(21)}get config(){return{info:this.info,init:this.init,loader_config:this.loader_config,runtime:this.runtime}}run(){try{const t=d(this.agentIdentifier),r=[...this.desiredFeatures];r.sort(((e,t)=>a.P3[e.featureName]-a.P3[t.featureName])),r.forEach((r=>{if(!t[r.featureName]&&r.featureName!==a.K7.pageViewEvent)return;if(this.runSoftNavOverSpa&&r.featureName===a.K7.spa)return;if(!this.runSoftNavOverSpa&&r.featureName===a.K7.softNav)return;const n=function(e){switch(e){case a.K7.ajax:return[a.K7.jserrors];case a.K7.sessionTrace:return[a.K7.ajax,a.K7.pageViewEvent];case a.K7.sessionReplay:return[a.K7.sessionTrace];case a.K7.pageViewTiming:return[a.K7.pageViewEvent];default:return[]}}(r.featureName).filter((e=>!(e in this.features)));n.length>0&&(0,e.R)(36,{targetFeature:r.featureName,missingDependencies:n}),this.features[r.featureName]=new r(this)}))}catch(t){(0,e.R)(22,t);for(const e in this.features)this.features[e].abortHandler?.();const r=(0,x.Zm)();delete r.initializedAgents[this.agentIdentifier]?.api,delete r.initializedAgents[this.agentIdentifier]?.features,delete this.sharedAggregator;return r.ee.get(this.agentIdentifier).abort(),!1}}}({features:[R,_,_e,Ne,he,N,L,Pe,ke],loaderType:"pro"})})()})();</script> <meta charset="UTF-8" /> <meta name="keywords" content="CD20, CD20 Antibody Pair (H00000931-AP22), Novus Biologicals, H00000931-AP22" /> <link rel="canonical" href="https://www.novusbio.com/products/cd20-antibody-pair_h00000931-ap22" /> <title>CD20 Antibody Pair (H00000931-AP22): Novus Biologicals</title> <meta name="description" content="CD20 Antibody Pair. Matched antibody pairs validated for ELISA or IP-Western Blot. Backed by our 100% Guarantee." /> <meta property="og:description" content="CD20 Antibody Pair. Matched antibody pairs validated for ELISA or IP-Western Blot. Backed by our 100% Guarantee." /> <meta property="og:image" content="//images.novusbio.com/thumbnails/CD20-Antibody-Pair-Sandwich-ELISA-H00000931-AP22-img0001.jpg" /> <meta refresh_date="11/20/2024 3:01:14 AM" /> <meta name="baidu-site-verification" content="xQr2vSIwwB" /> <script id="json-ld" type="application/ld+json">[{"@context":"http://schema.org","@type":"Product","description":"CD20 Antibody Pair. Tested Applications: Sandwich ELISA. Tested Reactivity: Human.","aggregateRating":[],"offers":{"@type":"Offer","price":949,"priceCurrency":"USD"},"url":"https://www.novusbio.com/products/cd20-antibody-pair_h00000931-ap22","name":"CD20 Antibody Pair","productID":"H00000931-AP22","mpn":"H00000931-AP22","sku":"H00000931-AP22","brand":{"@type":"Brand","name":"Novus Biologicals"},"itemcondition":"new","image":[{"@type":"ImageObject","url":"//images.novusbio.com/fullsize/CD20-Antibody-Pair-Sandwich-ELISA-H00000931-AP22-img0001.jpg","caption":"Sandwich ELISA: CD20 Antibody Pair [H00000931-AP22] - Detection sensitivity ranging from 0.03 ng/ml to 100 ng/ml.","width":400,"height":400}],"review":[],"isRelatedTo":[{"@type":"Product","name":"CD20 Antibodies","url":"https://www.novusbio.com/primary-antibodies/cd20"},{"@type":"Product","name":"CD20 Antibody Pair","url":"https://www.novusbio.com/antibody-pairs/cd20"},{"@type":"Product","name":"CD20 ELISA Kits","url":"https://www.novusbio.com/elisa-kits/cd20"},{"@type":"Product","name":"CD20 Lysates","url":"https://www.novusbio.com/lysates/cd20"},{"@type":"Product","name":"CD20 Proteins","url":"https://www.novusbio.com/proteins/cd20"}]},{"@context":"http://schema.org","@type":"CreativeWork","additionalType":"Citation","Headline":" Cerebrospinal fluid markers reveal intrathecal inflammation in progressive multiple sclerosis. ","isBasedOnUrl":"https://www.novusbio.com/products/cd20-antibody-pair_h00000931-ap22","datePublished":"2015-07-01","publisher":{"@type":"Organization","name":"Ann Neurol"},"author":{"@type":"person","name":"Komori M, Blake A, Greenwood M et al."}},{"@context":"http://schema.org","@type":"SiteNavigationElement","about":[{"@type":"Thing","url":"/support/sars-cov-research-resources","name":"COVID-19 Research Tools"},{"@type":"Thing","url":"/productsearch/novus","name":"Antibodies"},{"@type":"Thing","url":"/products/primary-antibodies","name":"Primary Antibodies"},{"@type":"Thing","url":"/conjugatedantibodies.html","name":"Conjugated Antibodies"},{"@type":"Thing","url":"/samplesize","name":"Sample Size Antibodies"},{"@type":"Thing","url":"/products/crispr-cas9-genetic-knockout-antibody-validation-reproducibility","name":"KO Validated Antibodies"},{"@type":"Thing","url":"https://www.novusbio.com/recombinant-monoclonals","name":"Recombinant Antibodies"},{"@type":"Thing","url":"/product-type/antibody-packs","name":"Antibody Sampler Packs"},{"@type":"Thing","url":"/product-type/antibody-pairs","name":"Antibody Pairs"},{"@type":"Thing","url":"/support/GeneralSecondaryAntibodies","name":"Secondary Antibodies"},{"@type":"Thing","url":"/products/isotype-controls","name":"Isotype Control Antibodies"},{"@type":"Thing","url":"/product-type/peptides-and-proteins","name":"Proteins and Peptides"},{"@type":"Thing","url":"/products/peptides-and-proteins","name":"Peptides & Proteins"},{"@type":"Thing","url":"/support/blocking-with-immunizing-peptide","name":"Blocking Peptides"},{"@type":"Thing","url":"/product-type/peptides-and-proteins%3Fapplications%3DBioactivity","name":"Biologically Active Proteins"},{"@type":"Thing","url":"https://www.novusbio.com/product-type/lysates","name":"Lysates and Cell Lines"},{"@type":"Thing","url":"/product-type/lysates","name":"Lysates"},{"@type":"Thing","url":"/research-areas/stem-cells/stem-cell-lines.html","name":"Stem Cell Lines"},{"@type":"Thing","url":"/product-type/kits","name":"Kits"},{"@type":"Thing","url":"/Lightning-Link%20Antibody%20Labeling%20Kits","name":"Antibody Labeling Kits"},{"@type":"Thing","url":"/product-type/kits%3Fcategory%3DKits%26kit_type%3DChIP%2520Kit","name":"ChIP Kits"},{"@type":"Thing","url":"/products/elisa-kits","name":"ELISA Kits"},{"@type":"Thing","url":"/product-type/kits%3Fcategory%3DKits%26kit_type%3DFlow%2520Cytometry%2520Kit","name":"Flow Cytometry Kits"},{"@type":"Thing","url":"/product-type/support-products%3Fcategory%3DSupport%2520Products%26applications%3DLigand%2520Activation","name":"Activators and Inhibitors"},{"@type":"Thing","url":"/product-type/inhibitors","name":"Inhibitors"},{"@type":"Thing","url":"/product-type/support-products%3Fcategory%3DSupport%2520Products%26applications%3DLigand%2520Activation","name":"Activators"},{"@type":"Thing","url":"/product-type/support-products","name":"Support Products"},{"@type":"Thing","url":"/research-topics/cell-biology/exosome-isolation-and-detection","name":"Exosome Isolation"},{"@type":"Thing","url":"/products/flow-cytometry-quality-control-beads","name":"Flow Cytometry Beads"},{"@type":"Thing","url":"/control-slides","name":"IHC Tissue Slides"},{"@type":"Thing","url":"/tissue-microarrays","name":"IHC Microarrays"},{"@type":"Thing","url":"/search%3Fkeywords%3Drunblue","name":"Western Blot Gels & Buffers"},{"@type":"Thing","url":"/product-type/wb-membranes","name":"Western Blot Membranes"},{"@type":"Thing","url":"/product-type/support-products","name":"All Support Products"},{"@type":"Thing","url":"/support/bulk-and-custom.html","name":"Bulk and Custom"},{"@type":"Thing","url":"/support.html","name":"Resources"},{"@type":"Thing","url":"/support/support-by-application.html","name":"Protocols"},{"@type":"Thing","url":"/support/video-protocols","name":"Video Protocols"},{"@type":"Thing","url":"/support/troubleshooting","name":"Troubleshooting Guides"},{"@type":"Thing","url":"/mailing-list","name":"Posters and Literature"},{"@type":"Thing","url":"/support/handbooks-and-guides","name":"Handbooks and Guides"},{"@type":"Thing","url":"/resources/calculators","name":"Calculators"},{"@type":"Thing","url":"/support/faqs.html","name":"FAQs"},{"@type":"Thing","url":"/antibody-news","name":"Blogs"},{"@type":"Thing","url":"/all-diseases.html","name":"Diseases"},{"@type":"Thing","url":"/whitepapers.html","name":"Whitepapers"},{"@type":"Thing","url":"/webform/help-finding-antibodies","name":"Antibody Concierge"},{"@type":"Thing","url":"/webinar","name":"Webinars"},{"@type":"Thing","url":"/research-tools.html","name":"Tools"},{"@type":"Thing","url":"/spectraviewer","name":"Spectra Viewer"},{"@type":"Thing","url":"/novusknowsflow.html","name":"Flow Cytometry Panel Builder"},{"@type":"Thing","url":"/application","name":"Application"},{"@type":"Thing","url":"/application/elisa","name":"ELISA"},{"@type":"Thing","url":"/application/flow-cytometry","name":"Flow Cytometry"},{"@type":"Thing","url":"https://www.novusbio.com/products/antibodies-cytof","name":"Mass Cytometry (CyTOF)"},{"@type":"Thing","url":"/application/icc","name":"ICC"},{"@type":"Thing","url":"/application/ihc","name":"IHC"},{"@type":"Thing","url":"/application/western-blotting","name":"Western Blotting"},{"@type":"Thing","url":"/interviews","name":"Interviews"},{"@type":"Thing","url":"/faculty/faculty-interviews","name":"Faculty"},{"@type":"Thing","url":"/postdoc/postdoc-interviews","name":"Postdoc"},{"@type":"Thing","url":"/research-areas.html","name":"By Research Area"},{"@type":"Thing","url":"/apoptosis-pathway","name":"Apoptosis"},{"@type":"Thing","url":"/autophagy-pathway","name":"Autophagy"},{"@type":"Thing","url":"/research-areas/cancer","name":"Cancer"},{"@type":"Thing","url":"/research-areas/cell-biology","name":"Cell Biology"},{"@type":"Thing","url":"/research-areas/cellular-markers","name":"Cellular Markers"},{"@type":"Thing","url":"/research-areas/epigenetics","name":"Epigenetics"},{"@type":"Thing","url":"/research-areas/epitope-tags","name":"Epitope Tags"},{"@type":"Thing","url":"/research-areas/cell-biology/Exosome-research-tools","name":"Exosomes Research"},{"@type":"Thing","url":"/research-areas/hypoxia","name":"Hypoxia"},{"@type":"Thing","url":"/research-areas/immunology","name":"Immunology"},{"@type":"Thing","url":"/research-areas/microbiology","name":"Microbiology"},{"@type":"Thing","url":"/research-areas/neuroscience","name":"Neuroscience"},{"@type":"Thing","url":"/research-areas/stem-cells","name":"Stem Cells"},{"@type":"Thing","url":"/pathwaypages.html","name":"By Pathway"},{"@type":"Thing","url":"/akt-signaling-pathway","name":"AKT "},{"@type":"Thing","url":"/mapkerkpathway.html","name":"ERK1/2/5 Pathway"},{"@type":"Thing","url":"/hedgehogpathway.html","name":"Hedgehog"},{"@type":"Thing","url":"/hippo-pathway.html","name":"Hippo"},{"@type":"Thing","url":"/jnk-signaling-pathway","name":"JNK Pathway"},{"@type":"Thing","url":"/mtor-pathway","name":"mTOR"},{"@type":"Thing","url":"/necroptosis-pathway","name":"Necroptosis"},{"@type":"Thing","url":"/nfkbpathway","name":"NFKB Signaling"},{"@type":"Thing","url":"/p38mapkpathway.html","name":"p38 Signaling"},{"@type":"Thing","url":"/tgfbetapathway","name":"TGF Beta"},{"@type":"Thing","url":"/toll-like-receptors","name":"TLR"},{"@type":"Thing","url":"/programs.html","name":"Customer Care"},{"@type":"Thing","url":"/guarantee","name":"100% Guarantee"},{"@type":"Thing","url":"/support/innovators-reward.html","name":"Risk Free Testing"},{"@type":"Thing","url":"/about/rewards.html","name":"Novus Rewards Program"},{"@type":"Thing","url":"/publications","name":"Publication Rewards Program"},{"@type":"Thing","url":"/newlab.html","name":"New Lab Discount"},{"@type":"Thing","url":"/scholarship-program.html","name":"Scholarship"},{"@type":"Thing","url":"/travelgrant.html","name":"Travel Grants"},{"@type":"Thing","url":"/products/promotions","name":"Promotions"},{"@type":"Thing","url":"/about.html","name":"About us"},{"@type":"Thing","url":"https://www.bio-techne.com/about/careers","name":"Careers"},{"@type":"Thing","url":"/about/collaborations.html","name":"Collaborations"},{"@type":"Thing","url":"/about/events","name":"Events"},{"@type":"Thing","url":"/about/novus-story.html","name":"Novus Story"},{"@type":"Thing","url":"/about/novus-team.html","name":"Our Team"},{"@type":"Thing","url":"/about/novus-philanthropy.html","name":"Philanthropy"},{"@type":"Thing","url":"/about/press-release.html","name":"Press Releases"},{"@type":"Thing","url":"/why-choose-novus.html","name":"Why choose Novus"},{"@type":"Thing","url":"/about/contact-us.html","name":"Contact Us"},{"@type":"Thing","url":"/about/contact-us.html","name":"Customer Service"},{"@type":"Thing","url":"/novus-distributors/list","name":"Distributors"},{"@type":"Thing","url":"/support/technical-support.html","name":"Technical Support"}]},{"@context":"http://schema.org","@type":"WPFooter","about":[{"@type":"Thing","url":"https://www.novusbio.com/productsearch/novus","name":"Antibodies"},{"@type":"Thing","url":"https://www.novusbio.com/product-type/secondary-antibodies","name":"Secondary Antibodies"},{"@type":"Thing","url":"https://www.novusbio.com/product-type/isotype-controls","name":"Isotype Controls"},{"@type":"Thing","url":"https://www.novusbio.com/product-type/peptides-and-proteins","name":"Proteins and Peptides"},{"@type":"Thing","url":"https://www.novusbio.com/product-type/elisa-kits","name":"ELISA Kits"},{"@type":"Thing","url":"https://www.novusbio.com/samplesize","name":"Sample Size"},{"@type":"Thing","url":"https://www.novusbio.comhttps://www.novusbio.com/new-product-information-page.html","name":"New Products"},{"@type":"Thing","url":"https://www.novusbio.com/about.html","name":"About Us"},{"@type":"Thing","url":"https://www.novusbio.comhttps://www.bio-techne.com/about/careers","name":"Careers"},{"@type":"Thing","url":"https://www.novusbio.com/guarantee","name":"Novus Guarantee"},{"@type":"Thing","url":"https://www.novusbio.com/about/contact-us.html","name":"Contact Us"},{"@type":"Thing","url":"https://www.novusbio.com/about/novus-team.html","name":"Our Team"},{"@type":"Thing","url":"https://www.novusbio.com/support/customer-service/privacy-policy.html","name":"Privacy Policy"},{"@type":"Thing","url":"https://www.novusbio.com/novus-bio-sitemap.html","name":"Sitemap"},{"@type":"Thing","url":"https://www.novusbio.com/about/contact-us.html","name":"Contact Us"},{"@type":"Thing","url":"https://www.novusbio.com/support/customer-service/terms.html","name":"Terms & Conditions"},{"@type":"Thing","url":"https://www.novusbio.com/support/technical-support.html","name":"Technical Support"},{"@type":"Thing","url":"https://www.novusbio.com/support/faqs.html","name":"FAQs"},{"@type":"Thing","url":"https://www.novusbio.com/webform/help-finding-antibodies","name":"Help Finding Antibodies"},{"@type":"Thing","url":"https://www.novusbio.com/support/support-by-application.html","name":"Protocols"}]},{"@context":"http://schema.org","@type":"WebPage","breadcrumb":{"@context":"http://schema.org","@type":"BreadcrumbList","itemListElement":[{"@context":"http://schema.org","@type":"ListItem","position":1,"item":{"@context":"http://schema.org","@type":"Thing","@id":"https://www.novusbio.com/","name":"Home"}},{"@context":"http://schema.org","@type":"ListItem","position":2,"item":{"@context":"http://schema.org","@type":"Thing","@id":"https://www.novusbio.com/common-name/cd20","name":"CD20"}},{"@context":"http://schema.org","@type":"ListItem","position":3,"item":{"@context":"http://schema.org","@type":"Thing","@id":"https://www.novusbio.com/antibody-pairs/cd20","name":"CD20 Antibody Pairs"}}]},"potentialaction":{"query":""}}]</script> <meta name="generator" content="Drupal 7 (https://www.drupal.org)" /> <link rel="shortlink" href="https://www.novusbio.com/products/cd20-antibody-pair_h00000931-ap22" /> <meta property="og:site_name" content="Novus Biologicals" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.novusbio.com/products/cd20-antibody-pair_h00000931-ap22" /> <meta property="og:title" content="CD20 Antibody Pair" /> <link type="text/css" rel="stylesheet" href="https://www.novusbio.com/sites/novusbio.com/files/css/css_LyQQziAp-Ie-zmhrx1RDdqrlziy3o8gvzDqRXCb00hg.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.novusbio.com/sites/novusbio.com/files/css/css_PKXTPBTTuSBPF7NSrNT2twmpZB05BY2cuOTz_4_8ORI.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.novusbio.com/sites/novusbio.com/files/css/css_epQTvxkLlfWLGSq94lW04RlDEK26840QgzyS2d_R_fw.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.novusbio.com/sites/novusbio.com/files/css/css_9eZvvH8xiAz18sT-zmuTZfYzHdV0O-FbSNe_tS771K4.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.novusbio.com/sites/novusbio.com/files/css/css_8-zvMULc0G5JczOUIWkZin0svexCP7R5pWo6msP_YwM.css" media="all" /> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_VUlliwzd-_is1_ryJskaiFlvPtaBpYuWsDxU6fMyUEk.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_c8LbWbHV1txem3q8oAzuadnL-HiBShaQH_WRviNqT_g.js"></script> <script type="text/javascript"> <![CDATA[//><!]]> </script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_4newT8cBOK9auTS1LAR6RL1VYq1INsyOKwxSb1E2BPI.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_L-CbsMNxXdHxvTeHTLjdXGdqfQk0RETDYk8CikUPuJI.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_4Vv8GAuPg4M6GWetVxgFDPNPYfVcP37nnmzoZnsPOj8.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_V5Fwoup1DkxxL-Rm-7is5QWj_MZhigWTY27_fmKn7S4.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_gqaUkMIJgkRbbe8vO9RRpMpmHEBt3qhSSwm3utDtnOw.js"></script> <script type="text/javascript"> <![CDATA[//><!]]> </script> <script type="text/javascript"> <![CDATA[//><!]]> </script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_MrgubHtdOA1nVcjDTR4s-m0ya_aIvugR02VlGxCGGDw.js"></script> <script type="text/javascript" src="https://www.novusbio.com/sites/novusbio.com/files/js/js_sNIdssRhxhJxJxAR2Pduc4_PqOXIKZf2m8g4hyLSJ8s.js"></script> <script type="text/javascript"> <![CDATA[//><!]]> </script> <link rel="shortcut icon" type="image/ico" href="//images.novusbio.com/design/faviconNew.ico"/> <meta name="yandex-verification" content="e7c24419f013b549"/> </head> <body class="html not-front not-logged-in no-sidebars page-products page-products-cd20-antibody-pair-h00000931-ap22" >  <noscript> <iframe src="https://www.googletagmanager.com/ns.html?id=GTM-52KXLL" height="0" width="0" style="display:none;visibility:hidden"></iframe> </noscript>  <div id="skip-link"> <a href="#main-content" class="element-invisible element-focusable">Skip to main content</a> </div> <noscript aria-hidden="true"><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-52KXLL" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>  <div class="region region-bt-brands-bar"> <div id="block-bt-brands-bar-bt-brands-bar" class="block block-bt-brands-bar"> <div class="content"> <div id="bt_brands_bar"> <div class="container_16"> <div style="margin-left: 0px; margin-right: 0px; width:960px;zoom:1;word-wrap:break-word;"> <ul> <li><a href="https://www.bio-techne.com" rel="noopener noreferrer" target="_blank" aria-label="Bio-Techne"><div class="brandsSprite_biotechne"></div></a></li><li><a href="https://www.rndsystems.com" rel="noopener noreferrer" target="_blank" aria-label="R&D Systems"><div class="brandsSprite_rndsystems"></div></a></li><li class="active"><div class="brandsSprite_novusbio_color"></div></li><li><a href="https://www.tocris.com" rel="noopener noreferrer" target="_blank" aria-label="Tocris Bioscience"><div class="brandsSprite_tocris"></div></a></li><li><a href="https://www.bio-techne.com/brands/proteinsimple" rel="noopener noreferrer" target="_blank" aria-label="ProteinSimple"><div class="brandsSprite_proteinsimple"></div></a></li><li><a href="https://www.biospacific.com" rel="noopener noreferrer" target="_blank" aria-label="BiosPacific"><div class="brandsSprite_biospacific"></div></a></li><li><a href="https://www.cliniqa.com" rel="noopener noreferrer" target="_blank" aria-label="Cliniqa"><div class="brandsSprite_cliniqa"></div></a></li><li><a href="https://acdbio.com/ " rel="noopener noreferrer" target="_blank" aria-label="ACD"><div class="brandsSprite_acd"></div></a></li><li><a href="https://www.rndheme.com" rel="noopener noreferrer" target="_blank" aria-label="R&D Heme"><div class="brandsSprite_rndheme"></div></a></li> </ul> </div> </div> </div> </div> </div> <div id="block-et-cookie-policy-cookie-policy" class="block block-et-cookie-policy"> <div class="content"> <div></div> </div> </div> </div> <div class="overlay"></div> <div id="header"> <div class="bluewide_wrapper"> <div class="container_16"> <div class="grid_16"> <div id="top_bar"> <div class="region region-top-left-bar"> <div id="block-et-internationalization-novus-dist-short" class="block block-et-internationalization"> <div class="content"> <div id="top_bar_support_info"><noscript>Support: 1-888-506-6887</noscript></div> </div> </div> </div> <div id="top_bar_novus"> <div class="region region-top-right-bar"> <div id="block-et-quickorder-et-quickorder" class="block block-et-quickorder"> <div class="content"> <div id="quickOrder_topbar">Quick Order  <div class="fp_quickorder_arrow"></div> <div id="quickOrder_dropdown"> <p class="quickOrder_disabled">Quick order is disabled in your country. Please contact Customer Service if you have questions.</p></div> </div> </div> </div> <div id="block-et-internationalization-country-dropdown" class="block block-et-internationalization"> <div class="content"> <div id="internationalization_country_select"> <div class="internationalization_drop"></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="content-wrapper" class="container_16"> <div class="grid_4"> <div id="logo"> <a href="/"><img src="//images.novusbio.com/design/novus_color_RGB_small.png" alt="Novus Biologicals Logo"></a> </div> </div> <div class="grid_12"> <div class="region region-login-area"> <div id="block-et-internationalization-sign-in" class="block block-et-internationalization"> <div class="content"> <div id="sign_in"><a href="/user/login" rel="nofollow"><noscript>Account</noscript></a></div> </div> </div> </div> <div class="search_form_container"> <div class="region region-search-bar"> <div id="block-et-searchbar-et-searchbar-bar" class="block block-et-searchbar"> <div class="content"> <div class="et_searchbar_wrapper"> <form name="et_searchbar" method="GET" action="/search" class="search_form"><div class="et_searchbar"> <input autocomplete="off" name="keywords" type="text" class="et_searchbar_wide et_searchbar_default" value="" placeholder="Enter Catalog #, Protein, or Keywords." data-default="" /><input type="submit" value="search" class="fp_mag_glass_wideSearch"></div></form><div class="et_spinner_small et_searchbar_spinner"></div> </div> </div> </div> </div>  </div> </div> <div class="clear"></div> </div> </div> <div class="bluewide_wrapper"> <div class="container_16"> <div class="grid_16" id="main_menu"> <div class="region region-header"> <div id="block-et-main-menu-et-main-menu-block" class="block block-et-main-menu"> <div class="content"> <div id="main_menu_wrapper"> <ul id="small_menu"> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_products" class="menu_drop"> <div class="mm_menu"><ul class="menu"><li class="first expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first leaf"><a href="/support/sars-cov-research-resources" title="">COVID-19 Research Tools</a></li> <li class="expanded"><a href="/productsearch/novus" title="">Antibodies</a><ul class="menu"><li class="first expanded"><a href="/products/primary-antibodies" title="">Primary Antibodies</a><ul class="menu"><li class="first leaf"><a href="/conjugatedantibodies.html" title="">Conjugated Antibodies</a></li> <li class="leaf"><a href="/samplesize" title="">Sample Size Antibodies</a></li> <li class="leaf"><a href="/products/crispr-cas9-genetic-knockout-antibody-validation-reproducibility" title="">KO Validated Antibodies</a></li> <li class="leaf"><a href="https://www.novusbio.com/recombinant-monoclonals" title="">Recombinant Antibodies</a></li> <li class="leaf"><a href="/product-type/antibody-packs" title="">Antibody Sampler Packs</a></li> <li class="last leaf"><a href="/product-type/antibody-pairs" title="">Antibody Pairs</a></li> </ul></li> <li class="leaf"><a href="/support/GeneralSecondaryAntibodies" title="">Secondary Antibodies</a></li> <li class="last leaf"><a href="/products/isotype-controls" title="">Isotype Control Antibodies</a></li> </ul></li> <li class="expanded"><a href="/product-type/peptides-and-proteins" title="">Proteins and Peptides</a><ul class="menu"><li class="first leaf"><a href="/products/peptides-and-proteins" title="">Peptides & Proteins</a></li> <li class="leaf"><a href="/support/blocking-with-immunizing-peptide" title="">Blocking Peptides</a></li> <li class="last leaf"><a href="/product-type/peptides-and-proteins?applications=Bioactivity" title="">Biologically Active Proteins</a></li> </ul></li> <li class="last expanded"><a href="https://www.novusbio.com/product-type/lysates" title="">Lysates and Cell Lines</a><ul class="menu"><li class="first leaf"><a href="/product-type/lysates" title="">Lysates</a></li> <li class="last leaf"><a href="/research-areas/stem-cells/stem-cell-lines.html" title="">Stem Cell Lines</a></li> </ul></li> </ul></li> <li class="last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first expanded"><a href="/product-type/kits" title="">Kits</a><ul class="menu"><li class="first leaf"><a href="/Lightning-Link%20Antibody%20Labeling%20Kits" title="">Antibody Labeling Kits</a></li> <li class="leaf"><a href="/product-type/kits?category=Kits&kit_type=ChIP%20Kit" title="">ChIP Kits</a></li> <li class="leaf"><a href="/products/elisa-kits" title="">ELISA Kits</a></li> <li class="last leaf"><a href="/product-type/kits?category=Kits&kit_type=Flow%20Cytometry%20Kit" title="">Flow Cytometry Kits</a></li> </ul></li> <li class="expanded"><a href="/product-type/support-products?category=Support%20Products&applications=Ligand%20Activation" title="">Activators and Inhibitors</a><ul class="menu"><li class="first leaf"><a href="/product-type/inhibitors" title="">Inhibitors</a></li> <li class="last leaf"><a href="/product-type/support-products?category=Support%20Products&applications=Ligand%20Activation" title="">Activators</a></li> </ul></li> <li class="expanded"><a href="/product-type/support-products" title="">Support Products</a><ul class="menu"><li class="first leaf"><a href="/research-topics/cell-biology/exosome-isolation-and-detection" title="Exosome Isolation and Detection Tools">Exosome Isolation</a></li> <li class="leaf"><a href="/products/flow-cytometry-quality-control-beads" title="Flow Cytometry Calibration, Compensation and Cell Counting Beads">Flow Cytometry Beads</a></li> <li class="leaf"><a href="/control-slides" title="">IHC Tissue Slides</a></li> <li class="leaf"><a href="/tissue-microarrays" title="">IHC Microarrays</a></li> <li class="leaf"><a href="/search?keywords=runblue" title="">Western Blot Gels & Buffers</a></li> <li class="leaf"><a href="/product-type/wb-membranes" title="">Western Blot Membranes</a></li> <li class="last leaf"><a href="/product-type/support-products" title="">All Support Products</a></li> </ul></li> <li class="last leaf"><a href="/support/bulk-and-custom.html" title="">Bulk and Custom</a></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/search?keywords=novus" class="main_menu_parent_link">Products</a> </div> </li> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_support" class="menu_drop"> <div class="mm_menu"><a href="/support/support-by-application.html"><div class="link_button link_protocols_button">Our Protocols</div></a><ul class="menu"><li class="first expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/support.html" title="">Resources</a><ul class="menu"><li class="first leaf"><a href="/support/support-by-application.html" title="">Protocols</a></li> <li class="leaf"><a href="/support/video-protocols" title="">Video Protocols</a></li> <li class="leaf"><a href="/support/troubleshooting" title="">Troubleshooting Guides</a></li> <li class="leaf"><a href="/mailing-list" title="">Posters and Literature</a></li> <li class="leaf"><a href="/support/handbooks-and-guides" title="">Handbooks and Guides</a></li> <li class="leaf"><a href="/resources/calculators" title="">Calculators</a></li> <li class="leaf"><a href="/support/faqs.html" title="">FAQs</a></li> <li class="leaf"><a href="/antibody-news" title="">Blogs</a></li> <li class="leaf"><a href="/all-diseases.html" title="">Diseases</a></li> <li class="leaf"><a href="/whitepapers.html" title="">Whitepapers</a></li> <li class="leaf"><a href="/webform/help-finding-antibodies" title="">Antibody Concierge</a></li> <li class="last leaf"><a href="/webinar" title="">Webinars</a></li> </ul></li> </ul></li> <li class="last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first expanded"><a href="/research-tools.html" title="">Tools</a><ul class="menu"><li class="first leaf"><a href="/spectraviewer" title="">Spectra Viewer</a></li> <li class="last leaf"><a href="/novusknowsflow.html" title="">Flow Cytometry Panel Builder</a></li> </ul></li> <li class="expanded"><a href="/application" title="">Application</a><ul class="menu"><li class="first leaf"><a href="/application/elisa" title="">ELISA</a></li> <li class="leaf"><a href="/application/flow-cytometry" title="">Flow Cytometry</a></li> <li class="leaf"><a href="https://www.novusbio.com/products/antibodies-cytof" title="">Mass Cytometry (CyTOF)</a></li> <li class="leaf"><a href="/application/icc" title="">ICC</a></li> <li class="leaf"><a href="/application/ihc" title="">IHC</a></li> <li class="last leaf"><a href="/application/western-blotting" title="">Western Blotting</a></li> </ul></li> <li class="last expanded"><a href="/interviews" title="">Interviews</a><ul class="menu"><li class="first leaf"><a href="/faculty/faculty-interviews" title="">Faculty</a></li> <li class="last leaf"><a href="/postdoc/postdoc-interviews" title="">Postdoc</a></li> </ul></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/support.html" class="main_menu_parent_link">Resources</a> </div> </li> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_ra" class="menu_drop"> <div class="mm_menu"><a href="/pathwaypages.html"><div class="link_button">View Pathways</div></a><ul class="menu"><li class="first expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/research-areas.html" title="">By Research Area</a><ul class="menu"><li class="first leaf"><a href="/research-areas/apoptosis" title="">Apoptosis</a></li> <li class="leaf"><a href="/research-areas/autophagy" title="">Autophagy</a></li> <li class="leaf"><a href="/research-areas/cancer" title="">Cancer</a></li> <li class="leaf"><a href="/research-areas/cell-biology" title="">Cell Biology</a></li> <li class="leaf"><a href="/research-areas/cellular-markers" title="">Cellular Markers</a></li> <li class="leaf"><a href="/research-areas/epigenetics" title="">Epigenetics</a></li> <li class="leaf"><a href="/research-areas/epitope-tags" title="">Epitope Tags</a></li> <li class="leaf"><a href="/research-areas/cell-biology/Exosome-research-tools" title="Exosome Research Tools">Exosomes Research</a></li> <li class="leaf"><a href="/research-areas/hypoxia" title="">Hypoxia</a></li> <li class="leaf"><a href="/research-areas/immunology" title="">Immunology</a></li> <li class="leaf"><a href="/research-areas/microbiology" title="">Microbiology</a></li> <li class="leaf"><a href="/research-areas/neuroscience" title="">Neuroscience</a></li> <li class="last leaf"><a href="/research-areas/stem-cells" title="">Stem Cells</a></li> </ul></li> </ul></li> <li class="last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/pathwaypages.html" title="">By Pathway</a><ul class="menu"><li class="first leaf"><a href="/akt-signaling-pathway" title="">AKT </a></li> <li class="leaf"><a href="/apoptosis-pathway" title="">Apoptosis</a></li> <li class="leaf"><a href="/autophagy-pathway" title="">Autophagy</a></li> <li class="leaf"><a href="/mapkerkpathway.html" title="">ERK1/2/5 Pathway</a></li> <li class="leaf"><a href="/hedgehogpathway.html" title="">Hedgehog</a></li> <li class="leaf"><a href="/hippo-pathway.html" title="">Hippo</a></li> <li class="leaf"><a href="/jnk-signaling-pathway" title="">JNK Pathway</a></li> <li class="leaf"><a href="/mtor-pathway" title="">mTOR</a></li> <li class="leaf"><a href="/necroptosis-pathway" title="">Necroptosis</a></li> <li class="leaf"><a href="/nfkbpathway" title="">NFKB Signaling</a></li> <li class="leaf"><a href="/p38mapkpathway.html" title="">p38 Signaling</a></li> <li class="leaf"><a href="/tgfbetapathway" title="">TGF Beta</a></li> <li class="last leaf"><a href="/toll-like-receptors" title="">TLR</a></li> </ul></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/research-areas.html" class="main_menu_parent_link">Research Areas</a> </div> </li> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_promotions" class="menu_drop"> <div class="mm_menu"><a href="/about/rewards.html"><div class="link_button">Get Rewards</div></a><ul class="menu"><li class="first last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/programs.html" title="">Customer Care</a><ul class="menu"><li class="first leaf"><a href="/guarantee" title="">100% Guarantee</a></li> <li class="leaf"><a href="/support/innovators-reward.html" title="">Risk Free Testing</a></li> <li class="leaf"><a href="/about/rewards.html" title="">Novus Rewards Program</a></li> <li class="leaf"><a href="/publications" title="">Publication Rewards Program</a></li> <li class="leaf"><a href="/newlab.html" title="">New Lab Discount</a></li> <li class="leaf"><a href="/scholarship-program.html" title="">Scholarship</a></li> <li class="leaf"><a href="/travelgrant.html" title="">Travel Grants</a></li> <li class="last leaf"><a href="/products/promotions" title="">Promotions</a></li> </ul></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/programs.html" class="main_menu_parent_link">Customer Care</a> </div> </li> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_about" class="menu_drop"> <div class="mm_menu"><a href="/about/careers-at-novus.html"><div class="link_button">Novus Careers</div></a><ul class="menu"><li class="first last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/about.html" title="">About us</a><ul class="menu"><li class="first leaf"><a href="https://www.bio-techne.com/about/careers" title="">Careers</a></li> <li class="leaf"><a href="/about/collaborations.html" title="">Collaborations</a></li> <li class="leaf"><a href="/about/events" title="Events">Events</a></li> <li class="leaf"><a href="/about/novus-story.html" title="">Novus Story</a></li> <li class="leaf"><a href="/about/novus-team.html" title="">Our Team</a></li> <li class="leaf"><a href="/about/novus-philanthropy.html" title="">Philanthropy</a></li> <li class="leaf"><a href="/about/press-release.html" title="">Press Releases</a></li> <li class="last leaf"><a href="/why-choose-novus.html" title="">Why choose Novus</a></li> </ul></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/about.html" class="main_menu_parent_link">About Us</a> </div> </li> <li class="main_menu_parent"> <div class="main_menu_submenu"><div id="menu_contact" class="menu_drop"> <div class="mm_menu"><ul class="menu"><li class="first last expanded"><span title="" class="separator"><hr></span><ul class="menu"><li class="first last expanded"><a href="/about/contact-us.html" title="">Contact Us</a><ul class="menu"><li class="first leaf"><a href="/about/contact-us.html" title="">Customer Service</a></li> <li class="leaf"><a href="/novus-distributors/list" title="">Distributors</a></li> <li class="last leaf"><a href="/support/technical-support.html" title="">Technical Support</a></li> </ul></li> </ul></li> </ul><div class="clear"></div></div> </div></div> <div class="menu_header"> <a href="/about/contact-us.html" class="main_menu_parent_link">Contact</a> </div> </li> </ul> </div> </div> </div> </div> </div> </div> </div> <div id="caspertesting"> <div class="container_16"> <div id="page-breadcrumb" class="grid_16"> <div class="breadcrumb"><a href="/">Home</a> » <a href="/common-name/cd20">CD20</a> » <a href="/antibody-pairs/cd20">CD20 Antibody Pairs</a> » CD20 Antibody Pair</div> </div> <div class="main grid_16">  <div class="region region-banners"> <div id="block-block-26" class="block block-block"> <div class="content"> <div class="container_12"><a href="https://www.bio-techne.com/account/novus-bio-techne/login?_ga=2.17257593.151271452<br />
5.1724696046-473375462.1712005244" style="margin: 0 10px;" target="_blank"><img alt="Novus Biologicals products are now on bio-techne.com" src="https://images.novusbio.com/design/ready-to-buy-novus-products-login.png" style="height:120px; width:940px" /></a></div> </div> </div> </div> <h1>CD20 Antibody Pair</h1> </div> <div class="clear"></div> <div> <div class="region region-content"> <div id="block-et-messages-et-messages-block" class="block block-et-messages"> <div class="content"> <span></span> </div> </div> <div id="block-system-main" class="block block-system"> <div class="content"> <div class="grid_16"><div class="ds_info float_left"><a href="#PublicationSection"><div class="sprite_pubBook_large"></div></a> <a href="#PublicationSection" class="bottom2"><span class="ctr">(1 Publication)</span></a></div><div class="ds_info float_left"> <a href="/common-name/cd20"><div class="sprite_allRelated"></div></a> <a href="/common-name/cd20" class="bottom4"><span class="ctr">See All Related</span></a> </div><div class="ds_info float_left"><a href="/reviews/H00000931-AP22"><div class="dsSprite_submitreview"></div></a> <a href="/reviews/H00000931-AP22" class="bottom4"><span class="ctr">Submit a Review</span></a></div></div></div><div class="modalWrapper" style="display:none;"> <h2>Species Glossary</h2> <hr class="customhr"/> <img src="//images.novusbio.com/design/bunny.gif" alt="Species Glossary Rabbit" style="float: right;"> <table class="modalTable"> <tr> <td>At</td> <td>=</td> <td>A. thaliana</td> <td>SyHa</td> <td>=</td> <td>Golden Syrian Hamster</td> </tr> <tr> <td>All</td> <td>=</td> <td>All Species</td> <td>Ha</td> <td>=</td> <td>Hamster</td> </tr> <tr> <td>An</td> <td>=</td> <td>Animal</td> <td>Hu</td> <td>=</td> <td>Human</td> </tr> <tr> <td>ArHa</td> <td>=</td> <td>Armenian Hamster</td> <td>I</td> <td>=</td> <td>Insect</td> </tr> <tr> <td>Av</td> <td>=</td> <td>Avian</td> <td>Ll</td> <td>=</td> <td>Llama</td> </tr> <tr> <td>Bb</td> <td>=</td> <td>Baboon</td> <td>Ma</td> <td>=</td> <td>Mammal</td> </tr> <tr> <td>Ba</td> <td>=</td> <td>Bacteria</td> <td>Mk</td> <td>=</td> <td>Monkey</td> </tr> <tr> <td>Bv</td> <td>=</td> <td>Bovine</td> <td>Mu</td> <td>=</td> <td>Mouse</td> </tr> <tr> <td>Ca</td> <td>=</td> <td>Canine</td> <td>Multi</td> <td>=</td> <td>Multi-species</td> </tr> <tr> <td>Ce</td> <td>=</td> <td>C. Elegans</td> <td>NA</td> <td>=</td> <td>Non-species specific</td> </tr> <tr> <td>Ch</td> <td>=</td> <td>Chicken</td> <td>Or</td> <td>=</td> <td>Orangutan</td> </tr> <tr> <td>ChHa</td> <td>=</td> <td>Chinese Hamster</td> <td>Pl</td> <td>=</td> <td>Plant</td> </tr> <tr> <td>Cm</td> <td>=</td> <td>Cynomolgus Monkey</td> <td>Pm</td> <td>=</td> <td>Primate</td> </tr> <tr> <td>Do</td> <td>=</td> <td>Donkey</td> <td>Po</td> <td>=</td> <td>Porcine</td> </tr> <tr> <td>Dr</td> <td>=</td> <td>Drosophilia</td> <td>Rb</td> <td>=</td> <td>Rabbit</td> </tr> <tr> <td>Ec</td> <td>=</td> <td>E. Coli</td> <td>Rt</td> <td>=</td> <td>Rat</td> </tr> <tr> <td>Eq</td> <td>=</td> <td>Equine</td> <td>RM</td> <td>=</td> <td>Rhesus Macaque</td> </tr> <tr> <td>Fe</td> <td>=</td> <td>Feline</td> <td>Sh</td> <td>=</td> <td>Sheep</td> </tr> <tr> <td>Ft</td> <td>=</td> <td>Ferret</td> <td>Vb</td> <td>=</td> <td>Vertebrate</td> </tr> <tr> <td>Fi</td> <td>=</td> <td>Fish</td> <td>Vi</td> <td>=</td> <td>Virus</td> </tr> <tr> <td>Fu</td> <td>=</td> <td>Fungi</td> <td>Xp</td> <td>=</td> <td>Xenopus</td> </tr> <tr> <td>Ge</td> <td>=</td> <td>Gerbil</td> <td>Ye</td> <td>=</td> <td>Yeast</td> </tr> <tr> <td>GP</td> <td>=</td> <td>Guinea Pig</td> <td>Ze</td> <td>=</td> <td>Zebrafish</td> </tr> <tr> <td>Gt</td> <td>=</td> <td>Goat</td> </tr> </table> <div style="text-align: center;margin-left:25px;margin-right:25px;"> <p>Note: Mouseover a species abbreviation on the product page to display the fullname.</p> </div> </div> </div><div class="clear"></div><div class="grid_10 pos_relative"><div class="ds_blue_border equaltop"><div class="imagesleft equaltop"><h2 class="blueHead">Images</h2> <div class="midBlue"> </div><div class="images"><div class="cycle-slideshow slideshows" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-top" data-cycle-prev="#ss_prev_top" data-cycle-next="#ss_next_top" data-cycle-caption="#image-caption" data-cycle-caption-template="Image {{slideNum}} of {{slideCount}}" data-cycle-slides=".big_thumb_container" data-cycle-carousel-visible="1" id="images_cycle" > <div class="sub_image_wrapper"><div id="cycle-circle-pager-top" class="cycle-circle-pager"></div><div id="image-caption"></div> <a class="enlargeTop">(<div class="dsSprite_magGlass"></div> Enlarge)</a></div> <div class="big_thumb_container"> <div class="image_wrapper"> <a href="//images.novusbio.com/fullsize/CD20-Antibody-Pair-Sandwich-ELISA-H00000931-AP22-img0001.jpg" class="top_images" rel="gallery" title="Sandwich ELISA: CD20 Antibody Pair [H00000931-AP22] - Detection sensitivity ranging from 0.03 ng/ml to 100 ng/ml." > <img src="//images.novusbio.com/images/CD20-Antibody-Pair-Sandwich-ELISA-H00000931-AP22-img0001.jpg" class="big_thumb" alt="Sandwich ELISA: CD20 Antibody Pair [H00000931-AP22] - Detection sensitivity ranging from 0.03 ng/ml to 100 ng/ml." title="Sandwich ELISA: CD20 Antibody Pair [H00000931-AP22] - Detection sensitivity ranging from 0.03 ng/ml to 100 ng/ml." /> </a> </div> <div class="alt-caption padding_left5" >Sandwich ELISA: CD20 Antibody Pair [H00000931-AP22] - Detection sensitivity ranging from 0.03 ng/ml to 100 ng/ml.</div> </div></div></div></div><div class="productsright pos_relative equaltop"><h2 class="blueHead">Product Details</h2> <div class="midBlue">Summary</div><table class="ds_list"><tr class="lined"> <td><strong>Reactivity</strong></td> <td><span title='Human'>Hu</span><span class="myModal">Species Glossary</span></td> </tr><tr class="lined"> <td><strong>Applications</strong></td> <td><span title='ELISA'>ELISA</span></td> </tr><tr class="lined"> <td><strong>Standard Curve Range</strong></td> <td><div>0.03 ng/ml to 100 ng/ml</div></td> </tr></table></div> </div></div><div class="grid_6"><div></div> <div class="ds_blue_border equaltop"> <h2 class="blueHead_nopadding">Order Details</h2><ul class="ds_details"><li class="add-to-cart" data-type="full" data-prodname="" data-catnum="H00000931-AP22" data-catnums="H00000931-AP22" data-disabled=''><noscript><form autocomplete="off" action="/products/cd20-antibody-pair_h00000931-ap22" method="post" id="et-add-multiple-to-cart-form" accept-charset="UTF-8"><div><table class="sticky-enabled"> <thead><tr><th>Size</th><th>Price</th> </tr></thead> <tbody> <tr class="odd"><td><div class="atc_size" title="catalog # H00000931-AP22">1 Set</div><div data-msg='' class="atc_catnum">H00000931-AP22</div></td><td><div style="font-size:11px;"><a class="jump_distributor" href="#jump_distributor">Contact Your<br />Distributor</a></div></td> </tr> <tr class="even"><td colspan="3" class="stock_row">9-11 Business Days</td> </tr> </tbody> </table> <input type="hidden" name="form_build_id" value="form-wz0Nups0OUnbSpf4Mc0jL9Sd-Gbln5jog3rLyHzymh4" /> <input type="hidden" name="form_id" value="et_add_multiple_to_cart_form" /> </div></form></noscript></li></ul><div id="shipping" class="hidden"></td></tr></div><div class="conj_form_buttons"></div><div id="shipping_statement"><span id="shipping_rate"></span></div><div class="shipping_obt_transfer"><span>Novus Biologicals is part of Bio-Techne</span><br><br><a href="https://www.bio-techne.com/p/elisa-kits/cd20-antibody-pair_h00000931-ap22" rel="follow" class="btn btn-primary">Shop this product on bio-techne.com</a></div><br><div class="learn_more"> <a href="/guarantee"> <div class="sprite_noImage" title="Novus Biologicals, part of Bio-Techne, offers 100% Guarantee"></div> <div class="learn_more_text">Novus Biologicals, part of Bio-Techne, offers 100% Guarantee</div></a> </div><span id="conj_form" class="hidden"><tr><td colspan="4"></td></tr></span> </div> </div><div class="clear"></div><div class="grid_10"><div><div id="ds_tabs" style="display:none;"> <div class="ds_tab_active" id="dsTabs_datasheet" data-anchor_desc="datasheet">Datasheet</div> <div class="ds_tab" id="dsTabs_reviews-publications" data-anchor_desc="reviews-publications">Reviews & Publications</div> <div class="ds_tab" id="dsTabs_protocols-faqs" data-anchor_desc="protocols-faqs">Protocols & FAQs</div> <div class="ds_tab" id="dsTabs_supportresearch" data-anchor_desc="supportresearch">Support & Research</div> </div><div class="ds_tab_content equalbottom" id="content_datasheet" > <a id="datasheet"></a><h2 class=greyHead2>CD20 Antibody Pair Summary</h2> <div class="ds_info"> <a id="tab1details"></a> <table class="ds_list wide" style="table-layout:fixed;"> <tr class="lined"> <td><strong>Description</strong></td> <td><div class="full_description">Quality control test: Standard curve using recombinant protein (H00000931-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human MS4A1.</div></td> </tr><tr class="lined"> <td><strong>Standard Curve Range</strong></td> <td><div>0.03 ng/ml to 100 ng/ml</div></td> </tr><tr class="lined"> <td><strong>Assay Type</strong></td> <td><div>Sandwich ELISA</div></td> </tr><tr class="lined"> <td><strong>Gene</strong></td> <td><div>MS4A1</div></td> </tr> </table> </div> <h2 class="greyHead2">Applications/Dilutions</h2> <div class="ds_info"> <a id="tab1appsdiluts"></a> <table class="ds_list wide"> <tr class="lined"> <td><strong>Dilutions</strong></td> <td> <ul class="ds_noDotList"><li>Sandwich ELISA 0.03 ng/ml - 100 ng/ml</li> </ul> </td> </tr><tr class="lined"> <td><strong>Application Notes</strong></td> <td><div>Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.</div></td> </tr><tr class="lined"> <td><strong>Publications</strong></td> <td> <table> <tr> <td>Read <a href="#PublicationSection"> Publication</a> using H00000931-AP22.<br /></td> </tr> </table> </td> </tr> </table> </div> <h2 class="greyHead2">Packaging, Storage & Formulations</h2><div class="ds_info"><table class="ds_list"><tr class="lined"> <td><strong>Storage</strong></td> <td><div>Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.</div></td> </tr><tr class="lined"> <td><strong>Buffer</strong></td> <td><div>1x PBS, pH 7.4</div></td> </tr></table></div> <h2 class="greyHead2">Kit Components</h2><div> <a id="tab1kitcomponents"></a> <table class="ds_list wide top"> <tr> <td> <strong>Components</strong> </td> <td> <ol style="margin:0px;padding:0px;padding-left:21px;"><li>Capture antibody: rabbit MaxPab affinity purified polyclonal anti-MS4A1 (100 ug)</li><li>Detection antibody: mouse purified polyclonal anti-MS4A1 (20 ug)</li> </ol> </td> </tr> </table> </div> <h2 class="greyHead2">Notes</h2><div class="ds_info"> <a id="tab1notes"></a> <div>This product is produced by and distributed for Abnova, a company based in Taiwan.</div> </div><h2 class="greyHead2">Alternate Names for CD20 Antibody Pair</h2> <div class="ds_info"> <a id="tab1altnames"></a> <div class="information-list"> <ul><li>B1</li><li>B-lymphocyte antigen CD20</li><li>B-lymphocyte cell-surface antigen B1</li><li>B-lymphocyte surface antigen B1</li><li>Bp35</li><li>Bp35MGC3969</li><li>CD20 antigen</li><li>CD20 receptor</li><li>CD20</li><li>CD20S7</li><li>CVID5</li><li>LEU-16</li><li>Leukocyte surface antigen Leu-16</li><li>Ly-44</li><li>Membrane-spanning 4-domains subfamily A member 1</li><li>membrane-spanning 4-domains, subfamily A, member 1</li><li>MS4A1</li><li>MS4A2</li><li>S7</li></ul></div> </div> <h2 class="greyHead2">Background</h2> <div class="ds_info"> <a id="tab1background"></a> <div>CD20 is a non-glycosylated phosphoprotein that is expressed on the surface of normal and malignant B cells and functions in mediating calcium transport and B cell differentiation (1,2). CD20 is encoded by the membrane-spanning 4-domain family A member 1 (MS4A1) gene and, in humans, is located on chromosome 11q12 (1). The CD20 protein is 297 amino acids (aa) in length with a theoretical molecular weight (MW) of 33 kDa (1,2). Structurally, the CD20 protein has four membrane-spanning domains, two extracellular loop domains, and intracellular N- and C-terminal domains (1,2). CD20 is expressed at specific stages of B cell maturation including pre-B cells, mature naive and activated B cells, and memory B cells, but is absent from plasmablasts and plasma cells (1,3,4). Expression of CD20 is often increased on malignant B cells associated with various B cell disorders such as chronic lymphocytic leukemia (CLL), multiple sclerosis (MS), and rheumatoid arthritis (2-4). Anti-CD20 monoclonal antibody (mAb)-based therapies have become an appealing target for treating these immune-related disorders and cancers (1-5). Rituximab, a chimeric mAb, was the first FDA approved CD20 monoclonal antibody for the treatment of non-Hodgkin's lymphoma that is now commonly used to treat MS (2,3). Since its initial approval in 1997, several other chimeric and humanized anti-CD20 mAbs have been developed including Ofatumumab, Ublituximab, and Obinutuzumab (1-5). B cell depletion via CD20 mAbs can occur under different mechanisms such as antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), complement-dependent cytotoxicity (CDC), and direct induction of apoptosis (1-4). Many ongoing studies are focused on combination therapies with CD20 mAbs as an addition to chemotherapy, B cell receptor (BCR) signaling inhibitors, or BH3 mimetics (1,2,4). Additionally, the effects of bispecific antibodies and CD20 chimeric antigen receptor (CAR) T cell therapies are under investigation for the treatment of B cell malignancies (4,5). <br/><br/>References<br/><br/>1. Pavlasova G, Mraz M. The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy. Haematologica. 2020; 105(6):1494-1506. https://doi.org/10.3324/haematol.2019.243543<br/><br/>2. Payandeh Z, Bahrami AA, Hoseinpoor R, et al. The applications of anti-CD20 antibodies to treat various B cells disorders. Biomed Pharmacother. 2019; 109:2415-2426. https://doi.org/10.1016/j.biopha.2018.11.121<br/><br/>3. Margoni M, Preziosa P, Filippi M, Rocca MA. Anti-CD20 therapies for multiple sclerosis: current status and future perspectives. J Neurol. 2022; 269(3):1316-1334. https://doi.org/10.1007/s00415-021-10744-x<br/><br/>4. Klein C, Jamois C, Nielsen T. Anti-CD20 treatment for B-cell malignancies: current status and future directions. Expert Opin Biol Ther. 2021; 21(2):161-181. https://doi.org/10.1080/14712598.2020.1822318<br/><br/>5. Sharman JP. Targeting CD20: teaching an old dog new tricks. Hematology Am Soc Hematol Educ Program. 2019; 2019(1):273-278. https://doi.org/10.1182/hematology.2019000031</div> </div> <h2 class="greyHead2">Limitations</h2> <div class="ds_info"> <a id="tab1background"></a> <div>This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are <a href="/support/quality-assurance.html">guaranteed</a> for 6 months from date of receipt.</div> </div><h2 class="greyHead2">Customers Who Viewed This Item Also Viewed...</h2> <a id="custalsoviewed"></a><div id="cav_prev"><div class="sprite_leftArrow"></div></div> <div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout=0 data-cycle-prev="#cav_prev" data-cycle-next="#cav_next" data-cycle-slides="div.ds_cav_group" id="ds_customer_also_viewed"><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP2-38449"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/plekhm1-antibody_nbp2-38449" style="overflow: hidden; width: 280px;" title="PLEKHM1 Antibody">PLEKHM1 Antibody</a>    </div><div class="sub-header">NBP2-38449</div> <div class="images_customers"><div id="ss_prev_cav0" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-0" data-cycle-prev="#ss_prev_cav0" data-cycle-next="#ss_next_cav0" data-cycle-slides="div.big_thumb_cust_container" data-index=0 ><div class="big_thumb_cust_container"> <a href="/products/plekhm1-antibody_nbp2-38449" title="Immunohistochemistry-Paraffin: PLEKHM1 Antibody [NBP2-38449] - Staining of human cerebral cortex shows moderate postivity in neuropil." class="cust_viewed_0" > <img loading="lazy" src="https://images.novusbio.com/images/PLEKHM1-Antibody-Immunohistochemistry-Paraffin-NBP2-38449-img0005.jpg" alt="Immunohistochemistry-Paraffin PLEKHM1 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/plekhm1-antibody_nbp2-38449" title="Immunohistochemistry-Paraffin: PLEKHM1 Antibody [NBP2-38449] - Staining of human fallopian tube shows moderate cytoplasmic postivity in glandular cells." class="cust_viewed_0" > <img loading="lazy" src="https://images.novusbio.com/images/PLEKHM1-Antibody-Immunohistochemistry-Paraffin-NBP2-38449-img0006.jpg" alt="Immunohistochemistry-Paraffin PLEKHM1 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/plekhm1-antibody_nbp2-38449" title="Immunohistochemistry-Paraffin: PLEKHM1 Antibody [NBP2-38449] - Staining of human placenta shows moderate granular cytoplasmic postivity in trophoblastic cells." class="cust_viewed_0" > <img loading="lazy" src="https://images.novusbio.com/images/PLEKHM1-Antibody-Immunohistochemistry-Paraffin-NBP2-38449-img0007.jpg" alt="Immunohistochemistry-Paraffin PLEKHM1 Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav0" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-0" class="cycle-circle-pager"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-P</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB600-1441"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/cd3-antibody-sp7_nb600-1441" style="overflow: hidden; width: 280px;" title="CD3 Antibody (SP7)">CD3 Antibody (SP7)</a>    </div><div class="sub-header">NB600-1441</div> <div class="images_customers"><div id="ss_prev_cav1" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-1" data-cycle-prev="#ss_prev_cav1" data-cycle-next="#ss_next_cav1" data-cycle-slides="div.big_thumb_cust_container" data-index=1 ><div class="big_thumb_cust_container"> <a href="/products/cd3-antibody-sp7_nb600-1441" title="Immunohistochemistry-Frozen: CD3 Antibody (SP7) [NB600-1441] - T-cells and microglia in mouse spinal cord with acute EAE. Mouse was perfused with 4% paraformaldehyde. Spinal cord was post-fixed overnight, followed by cryoprotection with 30% sucrose for 24h. Spinal cord sections were treated with antigen-retrieval buffer (pH 6.0) at 60C for 10 min, then cooled down to room temperature (this step should not be omitted). Anti-CD3 antibody was diluted at 1:200. Incubation: room temperature overnight. IHC-Fr image submitted by a verified customer review." class="cust_viewed_1" > <img loading="lazy" src="https://images.novusbio.com/images/CD3-Antibody-SP7-Immunohistochemistry-Frozen-NB600-1441-img0002.jpg" alt="Immunohistochemistry-Frozen CD3 Antibody (SP7)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd3-antibody-sp7_nb600-1441" title="Immunohistochemistry-Paraffin: CD3 Antibody (SP7) [NB600-1441] - Mouse lung tissue stained against C3aR normal conditions (left) and knockdown conditions (right). IHC-P image submitted by a verified customer review." class="cust_viewed_1" > <img loading="lazy" src="https://images.novusbio.com/images/CD3-Antibody-SP7-Immunohistochemistry-Paraffin-NB600-1441-img0003.jpg" alt="Immunohistochemistry-Paraffin CD3 Antibody (SP7)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd3-antibody-sp7_nb600-1441" title="Immunohistochemistry-Paraffin: CD3 Antibody (SP7) [NB600-1441] - FFPE human tonsil stained with CD3 antibody." class="cust_viewed_1" > <img loading="lazy" src="https://images.novusbio.com/images/CD3-Antibody-SP7-Immunohistochemistry-Paraffin-NB600-1441-img0001.jpg" alt="Immunohistochemistry-Paraffin CD3 Antibody (SP7)" class="big_thumb" /> </a> </div></div><div id="ss_next_cav1" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-1" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/cd3-antibody-sp7_nb600-1441#ReviewsSection"> <div class="sprite_5Stars"></div> (3 Reviews</a>) </div> <div class="tiny"> <a href="/products/cd3-antibody-sp7_nb600-1441#PublicationSection"> <div class="sprite_pubBook"></div> (44 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Ca, Hu, Mu, Po</div><div class="tiny"><strong>Applications:</strong> Flow, ICC/IF, IHC, IHC-Fr, IHC-P, KD</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="7268-CT"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-ctla-4-fc-chimera-cho-expressed-cf_7268-ct" style="overflow: hidden; width: 280px;" title="CTLA-4 [Unconjugated]">CTLA-4<br> [Unconjugated]</a>    </div><div class="sub-header">7268-CT</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-2" data-cycle-prev="#ss_prev_cav2" data-cycle-next="#ss_next_cav2" data-cycle-slides="div.big_thumb_cust_container" data-index=2 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-ctla-4-fc-chimera-cho-expressed-cf_7268-ct" title="Recombinant Human CTLA-4 Fc Chimera (Catalog # 7268-CT) inhibits IL-2 secretion by stimulated Jurkat human acute Tcell leukemia cells. The&amp;nbsp;ED50 for this effect is 0.03-0.15 μg/mL whenstimulated with 1 μg/mL Recombinant Human B7‑1/CD80 Fc Chimera (Catalog&amp;nbsp;# 140-B1). " class="cust_viewed_2" > <img loading="lazy" src="https://images.novusbio.com/images2/CTLA4_7268CT_2293.jpg" alt="Bioactivity CTLA-4 [Unconjugated]" class="big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-ctla-4-fc-chimera-cho-expressed-cf_7268-ct#PublicationSection"> <div class="sprite_pubBook"></div> (3 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP2-79843"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/hla-dq-dr-dp-antibody-hla-pan-2967r_nbp2-79843" style="overflow: hidden; width: 280px;" title="HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free">HLA DQ/DR/DP<br> Antibody (HLA-Pan/296 ...</a>    </div><div class="sub-header">NBP2-79843</div> <div class="images_customers"><div id="ss_prev_cav3" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-3" data-cycle-prev="#ss_prev_cav3" data-cycle-next="#ss_next_cav3" data-cycle-slides="div.big_thumb_cust_container" data-index=3 ><div class="big_thumb_cust_container"> <a href="/products/hla-dq-dr-dp-antibody-hla-pan-2967r_nbp2-79843" title="Protein Array: HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free [NBP2-79843] - Analysis of Protein Array containing more than 19,000 full-length human proteins using HLA DQ/DR/DP Antibody (HLA-Pan/2967R). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5." class="cust_viewed_3" > <img loading="lazy" src="https://images.novusbio.com/images/HLA-DQ-DR-DP-Antibody-HLA-Pan-2967R-Azide-and-BSA-Free-Protein-Array-NBP2-79843-img0001.jpg" alt="Protein Array HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/hla-dq-dr-dp-antibody-hla-pan-2967r_nbp2-79843" title="Immunocytochemistry/Immunofluorescence: HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free [NBP2-79843] - Immunofluorescence staining of Raji cells using HLA DQ/DR/DP Antibody (HLA-Pan/2967R) followed by goat anti-rabbit IgG-CF488 (Green). Nuclei stained with RedDot (Red)." class="cust_viewed_3" > <img loading="lazy" src="https://images.novusbio.com/images/HLA-DQ-DR-DP-Antibody-HLA-Pan-2967R-Azide-and-BSA-Free-Immunocytochemistry-Immunofluorescence-NBP2-79843-img0002.jpg" alt="Immunocytochemistry/ Immunofluorescence HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/hla-dq-dr-dp-antibody-hla-pan-2967r_nbp2-79843" title="Western Blot: HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free [NBP2-79843] - Western Blot Analysis of Ramos cell lysate using HLA DQ/DR/DP Antibody (HLA-Pan/2967R)." class="cust_viewed_3" > <img loading="lazy" src="https://images.novusbio.com/images/HLA-DQ-DR-DP-Antibody-HLA-Pan-2967R-Azide-and-BSA-Free-Western-Blot-NBP2-79843-img0003.jpg" alt="Western Blot HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav3" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-3" class="cycle-circle-pager"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NB100-524"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/nod2-antibody-2d9_nb100-524" style="overflow: hidden; width: 280px;" title="NOD2 Antibody (2D9) - BSA Free">NOD2 Antibody<br> (2D9) - BSA Free</a>    </div><div class="sub-header">NB100-524</div> <div class="images_customers"><div id="ss_prev_cav4" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-4" data-cycle-prev="#ss_prev_cav4" data-cycle-next="#ss_next_cav4" data-cycle-slides="div.big_thumb_cust_container" data-index=4 ><div class="big_thumb_cust_container"> <a href="/products/nod2-antibody-2d9_nb100-524" title="Flow Cytometry: NOD2 Antibody (2D9) [NB100-524] - An intracellular stain was performed on Jurkat cells with NOD2 (2D9) antibody NB100-524APC (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes." class="cust_viewed_4" > <img loading="lazy" src="https://images.novusbio.com/images/NOD2-Antibody-2D9-Flow-Cytometry-NB100-524-img0014.jpg" alt="Flow Cytometry NOD2 Antibody (2D9) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/nod2-antibody-2d9_nb100-524" title="Flow Cytometry: NOD2 Antibody (2D9) [NB100-524] - An intracellular stain was performed on Jurkat cells with NOD2 (2D9) antibody NB100-524PE (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeablized with 0.1% saponin. Cells were incubated in an antibody dilution of 2.5 ug/mL for 30 minutes.Both antibodies were conjugated to phycoerythrin." class="cust_viewed_4" > <img loading="lazy" src="https://images.novusbio.com/images/NOD2-Antibody-2D9-Flow-Cytometry-NB100-524-img0015.jpg" alt="Flow Cytometry NOD2 Antibody (2D9) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/nod2-antibody-2d9_nb100-524" title="Immunohistochemistry-Frozen: NOD2 Antibody (2D9) [NB100-524] - Overlay of NOD2-DyLight 488 (green) with phase contrast of murine colon. Image from verified customer review." class="cust_viewed_4" > <img loading="lazy" src="https://images.novusbio.com/images/NOD2-Antibody-2D9-Immunohistochemistry-Frozen-NB100-524-img0016.jpg" alt="Immunohistochemistry-Frozen NOD2 Antibody (2D9) - BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav4" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-4" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/nod2-antibody-2d9_nb100-524#ReviewsSection"> <div class="sprite_5Stars"></div> (1 Review</a>) </div> <div class="tiny"> <a href="/products/nod2-antibody-2d9_nb100-524#PublicationSection"> <div class="sprite_pubBook"></div> (26 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP2-25196"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/cd19-antibody-cb19_nbp2-25196" style="overflow: hidden; width: 280px;" title="CD19 Antibody (CB19) - BSA Free">CD19 Antibody<br> (CB19) - BSA Free</a>    </div><div class="sub-header">NBP2-25196</div> <div class="images_customers"><div id="ss_prev_cav5" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-5" data-cycle-prev="#ss_prev_cav5" data-cycle-next="#ss_next_cav5" data-cycle-slides="div.big_thumb_cust_container" data-index=5 ><div class="big_thumb_cust_container"> <a href="/products/cd19-antibody-cb19_nbp2-25196" title="Flow Cytometry: CD19 Antibody (CB19) [NBP2-25196] - Analysis using the FITC conjugate of NBP2-25196. Staining of CD19 in 10^6 human lymphocytes using 10 ul (0.25 ug) of this antibody. Shaded histogram represents cells without antibody; green represents isotype control ; red represents anti-CD19 antibody." class="cust_viewed_5" > <img loading="lazy" src="https://images.novusbio.com/images/CD19-Antibody-CB19-Flow-Cytometry-NBP2-25196-img0007.jpg" alt="Flow Cytometry CD19 Antibody (CB19) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd19-antibody-cb19_nbp2-25196" title="Flow Cytometry: CD19 Antibody (CB19) [NBP2-25196] - Analysis using the PE conjugate of NBP2-25196. Staining of CD19 in 1x10^6 human PBMC using 10 ul (0.25 ug) of was used to test this product. Propidium iodide negative lymphocyte population gated for analysis." class="cust_viewed_5" > <img loading="lazy" src="https://images.novusbio.com/images/CD19-Antibody-CB19-Flow-Cytometry-NBP2-25196-img0008.jpg" alt="Flow Cytometry CD19 Antibody (CB19) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd19-antibody-cb19_nbp2-25196" title="Flow Cytometry: CD19 Antibody (CB19) [NBP2-25196] - Analysis using the Alexa Fluor (R) 700 conjugate of NBP2-25196. Staining of human PBMC. Image from verified customer review." class="cust_viewed_5" > <img loading="lazy" src="https://images.novusbio.com/images/CD19-Antibody-CB19-Flow-Cytometry-NBP2-25196-img0009.jpg" alt="Flow Cytometry CD19 Antibody (CB19) - BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav5" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-5" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/cd19-antibody-cb19_nbp2-25196#ReviewsSection"> <div class="sprite_5Stars"></div> (1 Review</a>) </div> <div class="tiny"> <a href="/products/cd19-antibody-cb19_nbp2-25196#PublicationSection"> <div class="sprite_pubBook"></div> (12 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> CyTOF-ready, Flow, ICC/IF, In vitro, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF6457"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/rfc1-antibody_af6457" style="overflow: hidden; width: 280px;" title="RFC1 Antibody [Unconjugated]">RFC1 Antibody<br> [Unconjugated]</a>    </div><div class="sub-header">AF6457</div> <div class="images_customers"><div class="one_image_l"></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-6" data-cycle-prev="#ss_prev_cav6" data-cycle-next="#ss_next_cav6" data-cycle-slides="div.big_thumb_cust_container" data-index=6 ><div class="big_thumb_cust_container"> <a href="/products/rfc1-antibody_af6457" title="Western blot shows lysates of Daudi human Burkitt's lymphoma cell line. Gels were loaded with 30 µg of whole cell lysate (WCL), 20 µg of cytoplasmic (Cyto), and 10 µg of nuclear extracts (Nuc). PVDF Membrane was probed with 1 µg/mL of Sheep Anti-Human RFC1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6457) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for RFC1 at approximately 150 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="cust_viewed_6" > <img loading="lazy" src="https://images.novusbio.com/images2/RFC1_AF6457_Western_Blot_9874.jpg" alt="Western Blot RFC1 Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div class="one_image"></div><div class="one_image_11"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP1-89342"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/atp6v0a1-antibody_nbp1-89342" style="overflow: hidden; width: 280px;" title="ATP6V0A1 Antibody">ATP6V0A1 Antibody</a>    </div><div class="sub-header">NBP1-89342</div> <div class="images_customers"><div id="ss_prev_cav7" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-7" data-cycle-prev="#ss_prev_cav7" data-cycle-next="#ss_next_cav7" data-cycle-slides="div.big_thumb_cust_container" data-index=7 ><div class="big_thumb_cust_container"> <a href="/products/atp6v0a1-antibody_nbp1-89342" title="Immunocytochemistry/Immunofluorescence: ATP6V0A1 Antibody [NBP1-89342] - Staining of human cell line A-431 shows localization to the Golgi apparatus &amp; vesicles. Antibody staining is shown in green." class="cust_viewed_7" > <img loading="lazy" src="https://images.novusbio.com/images/ATP6V0A1-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-89342-img0006.jpg" alt="Immunocytochemistry/ Immunofluorescence ATP6V0A1 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/atp6v0a1-antibody_nbp1-89342" title="Immunohistochemistry-Paraffin: ATP6V0A1 Antibody [NBP1-89342] - Staining of human tonsil shows low expression as expected." class="cust_viewed_7" > <img loading="lazy" src="https://images.novusbio.com/images/ATP6V0A1-Antibody-Immunohistochemistry-Paraffin-NBP1-89342-img0011.jpg" alt="Immunohistochemistry-Paraffin ATP6V0A1 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/atp6v0a1-antibody_nbp1-89342" title="Immunohistochemistry-Paraffin: ATP6V0A1 Antibody [NBP1-89342] - Staining of human kidney shows strong cytoplasmic postivity in cells in tubules." class="cust_viewed_7" > <img loading="lazy" src="https://images.novusbio.com/images/ATP6V0A1-Antibody-Immunohistochemistry-Paraffin-NBP1-89342-img0013.jpg" alt="Immunohistochemistry-Paraffin ATP6V0A1 Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav7" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-7" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/atp6v0a1-antibody_nbp1-89342#ReviewsSection"> <div class="sprite_4Stars"></div> (1 Review</a>) </div> <div class="tiny"> <a href="/products/atp6v0a1-antibody_nbp1-89342#PublicationSection"> <div class="sprite_pubBook"></div> (13 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-P, IP, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP2-45946"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/rfc4-antibody-oti1a8_nbp2-45946" style="overflow: hidden; width: 280px;" title="RFC4 Antibody (OTI1A8)">RFC4 Antibody<br> (OTI1A8)</a>    </div><div class="sub-header">NBP2-45946</div> <div class="images_customers"><div id="ss_prev_cav8" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-8" data-cycle-prev="#ss_prev_cav8" data-cycle-next="#ss_next_cav8" data-cycle-slides="div.big_thumb_cust_container" data-index=8 ><div class="big_thumb_cust_container"> <a href="/products/rfc4-antibody-oti1a8_nbp2-45946" title="Immunocytochemistry/Immunofluorescence: RFC4 Antibody (OTI1A8) [NBP2-45946] - Analysis of COS7 cells transiently transfected by pCMV6-ENTRY RFC4." class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images/RFC4-Antibody-OTI1A8-Immunofluorescence-NBP2-45946-img0001.jpg" alt="Immunocytochemistry/ Immunofluorescence RFC4 Antibody (OTI1A8)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/rfc4-antibody-oti1a8_nbp2-45946" title="Immunohistochemistry: RFC4 Antibody (OTI1A8) [NBP2-45946] - Analysis of Carcinoma of Human pancreas tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)" class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images/RFC4-Antibody-OTI1A8-Immunohistochemistry-NBP2-45946-img0002.jpg" alt="Immunohistochemistry RFC4 Antibody (OTI1A8)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/rfc4-antibody-oti1a8_nbp2-45946" title="Immunohistochemistry: RFC4 Antibody (OTI1A8) [NBP2-45946] - Analysis of Human tonsil tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)" class="cust_viewed_8" > <img loading="lazy" src="https://images.novusbio.com/images/RFC4-Antibody-OTI1A8-Immunohistochemistry-NBP2-45946-img0003.jpg" alt="Immunohistochemistry RFC4 Antibody (OTI1A8)" class="big_thumb" /> </a> </div></div><div id="ss_next_cav8" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-8" class="cycle-circle-pager"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Ca, Hu, Pm, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-P, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP2-45570"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/rfc2-antibody-oti2b2_nbp2-45570" style="overflow: hidden; width: 280px;" title="RFC2 Antibody (OTI2B2)">RFC2 Antibody<br> (OTI2B2)</a>    </div><div class="sub-header">NBP2-45570</div> <div class="images_customers"><div id="ss_prev_cav9" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-9" data-cycle-prev="#ss_prev_cav9" data-cycle-next="#ss_next_cav9" data-cycle-slides="div.big_thumb_cust_container" data-index=9 ><div class="big_thumb_cust_container"> <a href="/products/rfc2-antibody-oti2b2_nbp2-45570" title="Flow Cytometry: RFC2 Antibody (2B2) [NBP2-45570] - Analysis of HEK293T cells transfected with either overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by RFC2 antibody." class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images/RFC2-Antibody-2B2-Flow-Cytometry-NBP2-45570-img0001.jpg" alt="Flow Cytometry RFC2 Antibody (OTI2B2)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/rfc2-antibody-oti2b2_nbp2-45570" title="Immunohistochemistry: RFC2 Antibody (2B2) [NBP2-45570] - Analysis of Human breast tissue." class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images/RFC2-Antibody-2B2-Immunohistochemistry-NBP2-45570-img0002.jpg" alt="Immunohistochemistry RFC2 Antibody (OTI2B2)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/rfc2-antibody-oti2b2_nbp2-45570" title="Immunohistochemistry: RFC2 Antibody (2B2) [NBP2-45570] - Analysis of Human Kidney tissue." class="cust_viewed_9" > <img loading="lazy" src="https://images.novusbio.com/images/RFC2-Antibody-2B2-Immunohistochemistry-NBP2-45570-img0003.jpg" alt="Immunohistochemistry RFC2 Antibody (OTI2B2)" class="big_thumb" /> </a> </div></div><div id="ss_next_cav9" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-9" class="cycle-circle-pager"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> Flow, IHC, IHC-P, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP2-67150"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/alpha-sarcoglycan-antibody-ja51-81_nbp2-67150" style="overflow: hidden; width: 280px;" title="alpha-Sarcoglycan Antibody (JA51-81)">alpha-Sarcoglycan<br> Antibody (JA51-81)</a>    </div><div class="sub-header">NBP2-67150</div> <div class="images_customers"><div id="ss_prev_cav10" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-10" data-cycle-prev="#ss_prev_cav10" data-cycle-next="#ss_next_cav10" data-cycle-slides="div.big_thumb_cust_container" data-index=10 ><div class="big_thumb_cust_container"> <a href="/products/alpha-sarcoglycan-antibody-ja51-81_nbp2-67150" title="Immunohistochemistry-Paraffin: alpha-Sarcoglycan Antibody (JA51-81) [NBP2-67150] - Analysis of paraffin-embedded mouse heart tissue using anti-alpha sarcoglycan antibody. Counter stained with hematoxylin." class="cust_viewed_10" > <img loading="lazy" src="https://images.novusbio.com/images/alpha-Sarcoglycan-Antibody-JA51-81-Immunohistochemistry-Paraffin-NBP2-67150-img0001.jpg" alt="Immunohistochemistry-Paraffin alpha-Sarcoglycan Antibody (JA51-81)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/alpha-sarcoglycan-antibody-ja51-81_nbp2-67150" title="Immunohistochemistry-Paraffin: alpha-Sarcoglycan Antibody (JA51-81) [NBP2-67150] - Analysis of paraffin-embedded mouse skeletal muscle tissue using anti-alpha sarcoglycan antibody. Counter stained with hematoxylin." class="cust_viewed_10" > <img loading="lazy" src="https://images.novusbio.com/images/alpha-Sarcoglycan-Antibody-JA51-81-Immunohistochemistry-Paraffin-NBP2-67150-img0002.jpg" alt="Immunohistochemistry-Paraffin alpha-Sarcoglycan Antibody (JA51-81)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/alpha-sarcoglycan-antibody-ja51-81_nbp2-67150" title="Immunohistochemistry-Frozen: alpha-Sarcoglycan Antibody (JA51-81) [NBP2-67150] - Human skeletal muscle tissue. IHC-Fr image submitted by a verified customer review." class="cust_viewed_10" > <img loading="lazy" src="https://images.novusbio.com/images/alpha-Sarcoglycan-Antibody-JA51-81-Immunohistochemistry-Frozen-NBP2-67150-img0005.jpg" alt="Immunohistochemistry-Frozen alpha-Sarcoglycan Antibody (JA51-81)" class="big_thumb" /> </a> </div></div><div id="ss_next_cav10" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-10" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/alpha-sarcoglycan-antibody-ja51-81_nbp2-67150#ReviewsSection"> <div class="sprite_5Stars"></div> (1 Review</a>) </div><div class="tiny"><strong>Species:</strong> Hu, Mu, Rt</div><div class="tiny"><strong>Applications:</strong> IHC, IHC-Fr, IHC-P, IP, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP1-59069"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/atp6v0a2-antibody_nbp1-59069" style="overflow: hidden; width: 280px;" title="ATP6V0A2 Antibody">ATP6V0A2 Antibody</a>    </div><div class="sub-header">NBP1-59069</div> <div class="images_customers"><div id="ss_prev_cav11" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-11" data-cycle-prev="#ss_prev_cav11" data-cycle-next="#ss_next_cav11" data-cycle-slides="div.big_thumb_cust_container" data-index=11 ><div class="big_thumb_cust_container"> <a href="/products/atp6v0a2-antibody_nbp1-59069" title="Western Blot: ATP6V0A2 Antibody [NBP1-59069] - Hela tissue lysate at a concentration of 1ug/ml." class="cust_viewed_11" > <img loading="lazy" src="https://images.novusbio.com/images/ATP6V0A2-Antibody-Western-Blot-NBP1-59069-img0001.jpg" alt="Western Blot ATP6V0A2 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/atp6v0a2-antibody_nbp1-59069" title="Western Blot: ATP6V0A2 Antibody [NBP1-59069] - HeLa cells, concentration 3.3 ug/ml." class="cust_viewed_11" > <img loading="lazy" src="https://images.novusbio.com/images/ATP6V0A2-Antibody-Western-Blot-NBP1-59069-img0002.jpg" alt="Western Blot ATP6V0A2 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/atp6v0a2-antibody_nbp1-59069" title="Immunohistochemistry-Paraffin: ATP6V0A2 Antibody [NBP1-59069] - overexpressed mouse sequences tissue" class="cust_viewed_11" > <img loading="lazy" src="https://images.novusbio.com/images/ATP6V0A2-Antibody-Immunohistochemistry-Paraffin-NBP1-59069-img0005.jpg" alt="Immunohistochemistry-Paraffin ATP6V0A2 Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav11" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-11" class="cycle-circle-pager"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-P, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP3-17255"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/gpha2-antibody_nbp3-17255" style="overflow: hidden; width: 280px;" title="GPHA2 Antibody">GPHA2 Antibody</a>    </div><div class="sub-header">NBP3-17255</div> <div class="images_customers"><div id="ss_prev_cav12" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-12" data-cycle-prev="#ss_prev_cav12" data-cycle-next="#ss_next_cav12" data-cycle-slides="div.big_thumb_cust_container" data-index=12 ><div class="big_thumb_cust_container"> <a href="/products/gpha2-antibody_nbp3-17255" title="Western Blot: GPHA2 Antibody [NBP3-17255] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10; Lane 2: RT4; Lane 3: U-251 MG; Lane 4: Human Plasma; Lane 5: Liver; Lane 6: Tonsil" class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images/GPHA2-Antibody-Western-Blot-NBP3-17255-img0002.jpg" alt="Western Blot GPHA2 Antibody" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/gpha2-antibody_nbp3-17255" title="Immunocytochemistry/Immunofluorescence: GPHA2 Antibody [NBP3-17255] - Staining of human cell line Hep G2 shows localization to vesicles." class="cust_viewed_12" > <img loading="lazy" src="https://images.novusbio.com/images/GPHA2-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-17255-img0001.jpg" alt="Immunocytochemistry/ Immunofluorescence GPHA2 Antibody" class="big_thumb" /> </a> </div></div><div id="ss_next_cav12" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-12" class="cycle-circle-pager"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> ICC/IF, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF1126"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/neprilysin-cd10-antibody_af1126" style="overflow: hidden; width: 280px;" title="Neprilysin/CD10 Antibody [Unconjugated]">Neprilysin/CD10<br> Antibody [Unconjugate</a>    </div><div class="sub-header">AF1126</div> <div class="images_customers"><div id="ss_prev_cav13" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-13" data-cycle-prev="#ss_prev_cav13" data-cycle-next="#ss_next_cav13" data-cycle-slides="div.big_thumb_cust_container" data-index=13 ><div class="big_thumb_cust_container"> <a href="/products/neprilysin-cd10-antibody_af1126" title="Neprilysin/CD10 was detected in perfusion fixed frozen sections of mouse brain (glial cell in hippocampus) using&amp;nbsp;15&amp;nbsp;µg/mL Goat Anti-Mouse Neprilysin/CD10 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1126) overnight at 4&amp;nbsp;°C. Tissue was stained (red) and counterstained (green). View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images2/Neprilysin_AF1126_Immunohistochemistry_6679.jpg" alt="Immunohistochemistry Neprilysin/CD10 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/neprilysin-cd10-antibody_af1126" title="Astrocyte‐specific Stat3 deletion increases microglial A beta internalization and degradation, and reduces apoE expression, dystrophic neurites, and detrimental cytokinesAInternalization of A beta (stained with IC16 antibody or methoxy‐XO4) was assessed using an engulfment assay, in which glial and A beta structures were surface‐rendered and A beta volumes co‐localized with glial volumes were quantified. Scale bars, 10 μm.B, CMicroglia (left Y axes) from APP/PS1 mice internalized significantly more A beta positive for IC16 or methoxy‐XO4 when Stat3 was deleted in astrocytes (*P &lt; 0.05, Mann–Whitney test), whereas no changes were seen in astrocytes (right axes; APP/PS1‐Stat3WT, n = 8 (four females and four males) mice; APP/PS1‐Stat3KO, n = 11 (five females and six males) mice; age, 11 months; Mann–Whitney test).D–H(D–F) Western blot quantification of protein levels of the A beta ‐degrading enzymes neprilysin/CD10 and CD36, as well as the A beta ‐binding apolipoprotein E (apoE), revealed a significantly increased expression of neprilysin and CD36 and a decreased expression of apoE (APP/PS1‐Stat3WT, n = 9 (five females and four males) mice; APP/PS1‐Stat3KO, n = 9 (five females and four males) mice; age, 11 months; *P &lt; 0.05, Mann–Whitney test for all comparisons). (G) In contrast, TREM2 expression remained unchanged (APP/PS1‐Stat3WT, n = 8 (four females and four males) mice; APP/PS1‐Stat3KO, n = 7 (four females and three males) mice; age, 11 months; Mann–Whitney test). (H) Western blots for proteins analyzed in (D‐G).Data information: Data are represented as mean ± SEM.Source data are available online for this figure. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/30617153), licensed under a CC-BY license. Not internally tested by R&amp;D Systems." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images/af1126_mouse-neprilysin-affinity-purified-polyclonal-ab-8220249505976.jpg" alt="Western Blot Neprilysin/CD10 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/neprilysin-cd10-antibody_af1126" title="Astrocyte‐specific Stat3 deletion increases microglial A beta internalization and degradation, and reduces apoE expression, dystrophic neurites, and detrimental cytokinesAInternalization of A beta (stained with IC16 antibody or methoxy‐XO4) was assessed using an engulfment assay, in which glial and A beta structures were surface‐rendered and A beta volumes co‐localized with glial volumes were quantified. Scale bars, 10 μm.B, CMicroglia (left Y axes) from APP/PS1 mice internalized significantly more A beta positive for IC16 or methoxy‐XO4 when Stat3 was deleted in astrocytes (*P &lt; 0.05, Mann–Whitney test), whereas no changes were seen in astrocytes (right axes; APP/PS1‐Stat3WT, n = 8 (four females and four males) mice; APP/PS1‐Stat3KO, n = 11 (five females and six males) mice; age, 11 months; Mann–Whitney test).D–H(D–F) Western blot quantification of protein levels of the A beta ‐degrading enzymes neprilysin/CD10 and CD36, as well as the A beta ‐binding apolipoprotein E (apoE), revealed a significantly increased expression of neprilysin and CD36 and a decreased expression of apoE (APP/PS1‐Stat3WT, n = 9 (five females and four males) mice; APP/PS1‐Stat3KO, n = 9 (five females and four males) mice; age, 11 months; *P &lt; 0.05, Mann–Whitney test for all comparisons). (G) In contrast, TREM2 expression remained unchanged (APP/PS1‐Stat3WT, n = 8 (four females and four males) mice; APP/PS1‐Stat3KO, n = 7 (four females and three males) mice; age, 11 months; Mann–Whitney test). (H) Western blots for proteins analyzed in (D‐G).Data information: Data are represented as mean ± SEM.Source data are available online for this figure. Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/30617153), licensed under a CC-BY license. Not internally tested by R&amp;D Systems." class="cust_viewed_13" > <img loading="lazy" src="https://images.novusbio.com/images/af1126_mouse-neprilysin-affinity-purified-polyclonal-ab-44202415433122.jpg" alt="Western Blot Neprilysin/CD10 Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav13" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-13" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/neprilysin-cd10-antibody_af1126#PublicationSection"> <div class="sprite_pubBook"></div> (22 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Mu</div><div class="tiny"><strong>Applications:</strong> ELISA(Cap), ELISA(Det), ELISA(Sta), IHC, IP, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="AF114"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/cd45-antibody_af114" style="overflow: hidden; width: 280px;" title="CD45 Antibody [Unconjugated]">CD45 Antibody<br> [Unconjugated]</a>    </div><div class="sub-header">AF114</div> <div class="images_customers"><div id="ss_prev_cav14" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-14" data-cycle-prev="#ss_prev_cav14" data-cycle-next="#ss_next_cav14" data-cycle-slides="div.big_thumb_cust_container" data-index=14 ><div class="big_thumb_cust_container"> <a href="/products/cd45-antibody_af114" title=" CD45 was detected in immersion fixed paraffin-embedded sections of mouse liver using Goat Anti-Mouse CD45 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF114) at 3&amp;nbsp;µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte&amp;#8482; HRP Polymer Antibody (Catalog&amp;nbsp;# VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to Kupffer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images2/CD45_AF114_Immunohistochemistry_23525.jpg" alt="Immunohistochemistry CD45 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd45-antibody_af114" title="CD45 was detected in immersion fixed RAW&amp;#160;264.7 mouse monocyte/macrophage cell line (positive staining) and Neuro&amp;#x2011;2A mouse neuroblastoma cell line (negative staining) using Goat Anti-Mouse CD45 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF114) at 5&amp;#160;&amp;micro;g/mL for 3 hours at room temperature. Cells were stained using the NorthernLights&amp;trade; 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to cell surface. Staining was performed using our protocol for Fluorescent ICC Staining of Non-adherent Cells." class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images2/af114_mouse-cd45-affinity-purified-polyclonal-ab-immunocytochemistry-6122021145449.jpg" alt="Immunocytochemistry CD45 Antibody [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd45-antibody_af114" title="The recruitment of CD45+F4/80+CD68+ macrophages was similar in the ASC-seeded DAT scaffolds that were cultured dynamically and statically for 14 days prior to implantation in the nu/nu mouse model. (A) Representative images showing CD45 (cyan), F4/80 (red), and CD68 (green) expression with DAPI counterstaining (blue) at 1-week post-implantation. Scale bars represent 100 μm. Boxed regions in the composite images are shown at higher magnification below. White arrowheads highlight CD45+F4/80+CD68+DAPI+ cells. (B) CD45+F4/80+CD68+DAPI+ cell density in the static and dynamic groups. (C) The percentage of CD45+F4/80+CD68+DAPI+ cells relative to the total CD45+DAPI+ cell population at 1, 4, and 8 weeks. *p &lt; 0.05, **p &lt; 0.01, ***p &lt; 0.001. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33816453), licensed under a CC-BY license. Not internally tested by R&amp;D Systems." class="cust_viewed_14" > <img loading="lazy" src="https://images.novusbio.com/images/af114_mouse-cd45-affinity-purified-polyclonal-ab-41202410331954.jpg" alt="Immunocytochemistry/ Immunofluorescence CD45 Antibody [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav14" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-14" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/cd45-antibody_af114#ReviewsSection"> <div class="sprite_4Stars"></div> (1 Review</a>) </div> <div class="tiny"> <a href="/products/cd45-antibody_af114#PublicationSection"> <div class="sprite_pubBook"></div> (70 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Mu</div><div class="tiny"><strong>Applications:</strong> CyTOF-ready, Flow, ICC, IHC, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP1-19371"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/cd4-antibody_nbp1-19371" style="overflow: hidden; width: 280px;" title="CD4 Antibody - BSA Free">CD4 Antibody - BSA<br> Free</a>    </div><div class="sub-header">NBP1-19371</div> <div class="images_customers"><div id="ss_prev_cav15" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-15" data-cycle-prev="#ss_prev_cav15" data-cycle-next="#ss_next_cav15" data-cycle-slides="div.big_thumb_cust_container" data-index=15 ><div class="big_thumb_cust_container"> <a href="/products/cd4-antibody_nbp1-19371" title="Immunohistochemistry-Frozen: CD4 Antibody [NBP1-19371] - Staining in mouse liver tissue." class="cust_viewed_15" > <img loading="lazy" src="https://images.novusbio.com/images/CD4-Antibody-Immunohistochemistry-Frozen-NBP1-19371-img0013.jpg" alt="Immunohistochemistry-Frozen CD4 Antibody - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd4-antibody_nbp1-19371" title="Immunohistochemistry-Paraffin: CD4 Antibody [NBP1-19371] - Alcohol-fixed paraffin-embedded rat spleen tissue. Dilution 1:150. Image from verified customer review." class="cust_viewed_15" > <img loading="lazy" src="https://images.novusbio.com/images/CD4-Antibody-Immunohistochemistry-Paraffin-NBP1-19371-img0014.jpg" alt="Immunohistochemistry-Paraffin CD4 Antibody - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd4-antibody_nbp1-19371" title="Flow Cytometry: CD4 Antibody [NBP1-19371] - An intracellular stain was performed on Jurkat cells with CD4 Antibody NBP1-19371R (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin. Cells were incubated in an antibody dilution of 5 ug/mL for 30 minutes at room temperature. Both antibodies were conjugated to DyLight 550." class="cust_viewed_15" > <img loading="lazy" src="https://images.novusbio.com/images/CD4-Antibody-Flow-Cytometry-NBP1-19371-img0015.jpg" alt="Flow Cytometry CD4 Antibody - BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav15" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-15" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/cd4-antibody_nbp1-19371#ReviewsSection"> <div class="sprite_4Stars"></div> (9 Reviews</a>) </div> <div class="tiny"> <a href="/products/cd4-antibody_nbp1-19371#PublicationSection"> <div class="sprite_pubBook"></div> (50 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Ca, Hu, Mu, Po, Rb, Rt</div><div class="tiny"><strong>Applications:</strong> Dual ISH-IHC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP2-70360"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/cd5-antibody-oti7a7_nbp2-70360" style="overflow: hidden; width: 280px;" title="CD5 Antibody (OTI7A7) - Azide and BSA Free">CD5 Antibody<br> (OTI7A7) - Azide and ...</a>    </div><div class="sub-header">NBP2-70360</div> <div class="images_customers"><div id="ss_prev_cav16" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-16" data-cycle-prev="#ss_prev_cav16" data-cycle-next="#ss_next_cav16" data-cycle-slides="div.big_thumb_cust_container" data-index=16 ><div class="big_thumb_cust_container"> <a href="/products/cd5-antibody-oti7a7_nbp2-70360" title="Western Blot: CD5 Antibody (OTI7A7) - Azide and BSA Free [NBP2-70360] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CD5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CD5." class="cust_viewed_16" > <img loading="lazy" src="https://images.novusbio.com/images/CD5-Antibody-OTI7A7-Azide-and-BSA-Free-Western-Blot-NBP2-70360-img0001.jpg" alt="Western Blot CD5 Antibody (OTI7A7) - Azide and BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd5-antibody-oti7a7_nbp2-70360" title="Flow Cytometry: CD5 Antibody (OTI7A7) - Azide and BSA Free [NBP2-70360] - Analysis of Jurkat cells, using anti-CD5 antibody, (Red), compared to a nonspecific negative control antibody (Blue)." class="cust_viewed_16" > <img loading="lazy" src="https://images.novusbio.com/images/CD5-Antibody-OTI7A7-Azide-and-BSA-Free-Flow-Cytometry-NBP2-70360-img0002.jpg" alt="Flow Cytometry CD5 Antibody (OTI7A7) - Azide and BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd5-antibody-oti7a7_nbp2-70360" title="Flow Cytometry: CD5 Antibody (OTI7A7) - Azide and BSA Free [NBP2-70360] - HEK293T cells transfected with either overexpression plasmid (Red) or empty vector control plasmid (Blue) were immunostaining by anti-CD5 antibody, and then analyzed by flow cytometry." class="cust_viewed_16" > <img loading="lazy" src="https://images.novusbio.com/images/CD5-Antibody-OTI7A7-Azide-and-BSA-Free-Flow-Cytometry-NBP2-70360-img0003.jpg" alt="Flow Cytometry CD5 Antibody (OTI7A7) - Azide and BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav16" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-16" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/cd5-antibody-oti7a7_nbp2-70360#ReviewsSection"> <div class="sprite_4Stars"></div> (1 Review</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> CyTOF-ready, Flow, IMC, ICC/IF, IHC, IHC-P, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP1-49045"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/cd8-antibody-53-67_nbp1-49045" style="overflow: hidden; width: 280px;" title="CD8 Antibody (53-6.7) - BSA Free">CD8 Antibody<br> (53-6.7) - BSA Free</a>    </div><div class="sub-header">NBP1-49045</div> <div class="images_customers"><div id="ss_prev_cav17" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-17" data-cycle-prev="#ss_prev_cav17" data-cycle-next="#ss_next_cav17" data-cycle-slides="div.big_thumb_cust_container" data-index=17 ><div class="big_thumb_cust_container"> <a href="/products/cd8-antibody-53-67_nbp1-49045" title="Immunohistochemistry-Paraffin: CD8 Antibody (53-6.7) [NBP1-49045] - CD8 alpha Antibody (53-6.7) [NBP1-49045] - CD8 alpha expression in mouse spleen tissue using anti-CD8 alpha antibody. Image from verified customer review." class="cust_viewed_17" > <img loading="lazy" src="https://images.novusbio.com/images/CD8-Antibody-53-6-7-Immunohistochemistry-Paraffin-NBP1-49045-img0004.jpg" alt="Immunohistochemistry-Paraffin CD8 Antibody (53-6.7) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd8-antibody-53-67_nbp1-49045" title="Immunocytochemistry/Immunofluorescence: CD8 Antibody (53-6.7) [NBP1-49045] - CD8 alpha Antibody (53-6.7) [NBP1-49045] - Analysis of bone marrow tissue by single and multiple staining." class="cust_viewed_17" > <img loading="lazy" src="https://images.novusbio.com/images/CD8-Antibody-53-6-7-Immunocytochemistry-Immunofluorescence-NBP1-49045-img0006.jpg" alt="Immunocytochemistry/ Immunofluorescence CD8 Antibody (53-6.7) - BSA Free" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/cd8-antibody-53-67_nbp1-49045" title="Immunohistochemistry-Frozen: CD8 Antibody (53-6.7) [NBP1-49045] - CD8 alpha Antibody (53-6.7) [NBP1-49045] - Analysis of mosue spleen sections. CD8+ lymphocytes are marked by brown labeling of the cell surface." class="cust_viewed_17" > <img loading="lazy" src="https://images.novusbio.com/images/CD8-Antibody-53-6-7-Immunohistochemistry-Frozen-NBP1-49045-img0008.jpg" alt="Immunohistochemistry-Frozen CD8 Antibody (53-6.7) - BSA Free" class="big_thumb" /> </a> </div></div><div id="ss_next_cav17" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-17" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/cd8-antibody-53-67_nbp1-49045#ReviewsSection"> <div class="sprite_4Stars"></div> (3 Reviews</a>) </div> <div class="tiny"> <a href="/products/cd8-antibody-53-67_nbp1-49045#PublicationSection"> <div class="sprite_pubBook"></div> (28 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Mu, Rt</div><div class="tiny"><strong>Applications:</strong> Cell Depl, CyTOF-ready, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, InhibTFunc</div> </div> </div> </div></div><div class="ds_cav_group"> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="NBP2-36776"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/hnrnp-c1-c2-antibody-cl2593_nbp2-36776" style="overflow: hidden; width: 280px;" title="hnRNP C1 + C2 Antibody (CL2593)">hnRNP C1 + C2<br> Antibody (CL2593)</a>    </div><div class="sub-header">NBP2-36776</div> <div class="images_customers"><div id="ss_prev_cav18" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-18" data-cycle-prev="#ss_prev_cav18" data-cycle-next="#ss_next_cav18" data-cycle-slides="div.big_thumb_cust_container" data-index=18 ><div class="big_thumb_cust_container"> <a href="/products/hnrnp-c1-c2-antibody-cl2593_nbp2-36776" title="Western Blot: hnRNP C1 + C2 Antibody (CL2593) [NBP2-36776] - Analysis in U-251MG cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-HNRNPC antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB." class="cust_viewed_18" > <img loading="lazy" src="https://images.novusbio.com/images/hnRNP-C1-+-C2-Antibody-CL2593-Western-Blot-NBP2-36776-img0015.jpg" alt="Western Blot hnRNP C1 + C2 Antibody (CL2593)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/hnrnp-c1-c2-antibody-cl2593_nbp2-36776" title="Immunohistochemistry: hnRNP C1 + C2 Antibody (CL2593) [NBP2-36776] - Staining of human rectum shows strong nuclear immunoreactivity in glandular and lamina propria cells." class="cust_viewed_18" > <img loading="lazy" src="https://images.novusbio.com/images/hnRNP-C1-+-C2-Antibody-CL2593-Immunohistochemistry-NBP2-36776-img0001.jpg" alt="Immunohistochemistry hnRNP C1 + C2 Antibody (CL2593)" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/hnrnp-c1-c2-antibody-cl2593_nbp2-36776" title="Immunohistochemistry: hnRNP C1 + C2 Antibody (CL2593) [NBP2-36776] - Staining of human small intestine shows strong nuclear positivity in glandular epithelium and in lamina propria cells." class="cust_viewed_18" > <img loading="lazy" src="https://images.novusbio.com/images/hnRNP-C1-+-C2-Antibody-CL2593-Immunohistochemistry-NBP2-36776-img0002.jpg" alt="Immunohistochemistry hnRNP C1 + C2 Antibody (CL2593)" class="big_thumb" /> </a> </div></div><div id="ss_next_cav18" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-18" class="cycle-circle-pager"></div></div> <div class="ds_info"><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> ICC/IF, IHC, IHC-P, KD, WB</div> </div> </div> </div> <div class="ds_cav_block"> <div class="ds_cav_upper" data-catnums="210-TA"> <div class="name"> <div class="flourish_left"></div> <div class="flourish_right"></div> <a href="/products/recombinant-human-tnf-alpha-protein_210-ta" style="overflow: hidden; width: 280px;" title="TNF-alpha [Unconjugated]">TNF-alpha<br> [Unconjugated]</a>    </div><div class="sub-header">210-TA</div> <div class="images_customers"><div id="ss_prev_cav19" class="cycle-pager"> <div class="pager_left_on"></div></div><div class="cycle-slideshow" data-cycle-fx="fade" data-cycle-timeout="0" data-cycle-pager="#cycle-circle-pager-19" data-cycle-prev="#ss_prev_cav19" data-cycle-next="#ss_next_cav19" data-cycle-slides="div.big_thumb_cust_container" data-index=19 ><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-tnf-alpha-protein_210-ta" title="1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa." class="cust_viewed_19" > <img loading="lazy" src="https://images.novusbio.com/images2/TNF-alpha_210-TA_256.jpg" alt="SDS-PAGE TNF-alpha [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-tnf-alpha-protein_210-ta" title="Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 25‑100 pg/mL." class="cust_viewed_19" > <img loading="lazy" src="https://images.novusbio.com/images2/TNFalpha_210TA_1658.jpg" alt="Bioactivity TNF-alpha [Unconjugated]" class="big_thumb" /> </a> </div><div class="big_thumb_cust_container"> <a href="/products/recombinant-human-tnf-alpha-protein_210-ta" title="Recombinant Human TNF-alpha (Catalog # 210-TA) has a molecular weight (MW) of 53.1 kDa as analyzed by SEC-MALS, suggesting that this protein is a homotrimer. MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation)." class="cust_viewed_19" > <img loading="lazy" src="https://images.novusbio.com/images/210-ta_recombinant-human-tnf-alpha-protein-sec-mals-35202312244..jpg" alt="SEC-MALS TNF-alpha [Unconjugated]" class="big_thumb" /> </a> </div></div><div id="ss_next_cav19" class="cycle-pager"><div class="pager_right_on"></div></div><div id="cycle-circle-pager-19" class="cycle-circle-pager"></div></div> <div class="ds_info"> <div class="tiny"> <a href="/products/recombinant-human-tnf-alpha-protein_210-ta#ReviewsSection"> <div class="sprite_5Stars"></div> (3 Reviews</a>) </div> <div class="tiny"> <a href="/products/recombinant-human-tnf-alpha-protein_210-ta#PublicationSection"> <div class="sprite_pubBook"></div> (811 Publications</a>) </div><div class="tiny"><strong>Species:</strong> Hu</div><div class="tiny"><strong>Applications:</strong> BA</div> </div> </div> </div></div> </div><div id="cav_next"><div class="sprite_rightArrow"></div></div> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_reviews-publications"> <a id="reviews-publications"></a><a id="PublicationSection"></a><h2 class="greyHead2">Publications for CD20 Antibody Pair (H00000931-AP22)(1)</h2><div class="ds_info"> <div>We have publications tested in 1 confirmed species: Human.<br /><br /><div class="align-right"> <button class="greybutton btn_width" name="novusreview" onclick="window.location='/publications'"; >Submit a Publication</button><br /> </div> </div><div> <div class="filterParent"> <div class="publications_filterList" id="pubapp"> <div class="blueHead">Filter By Application</div><div class="filter_clear" data-type="publication" data-filter="application">All Applications</div></div> <div class="publications_filterList" id="pubspec"> <div class="blueHead">Filter By Species</div><div class="filter_line"> <input type="checkbox" value="species" class="publication_filterCheckbox" data-filter="Human"> <div style="display:inline;">Human</div> (1)</div><div class="filter_clear" data-type="publication" data-filter="species">All Species</div></div> </div></div> <div class="clear"></div> <div id="publications_list">Showing Publication 1 - <span id="appcnt">1</span> of 1.<table class="wide lightPad tablesorter" id="publications_list_table"> <thead> <tr> <th>Publication using H00000931-AP22</th> <th>Applications</th> <th>Species</th> </tr> </thead> <tbody><tr class="lined revfil firstten" data-application="" data-species="Human"> <td><a href="http://www.ncbi.nlm.nih.gov/pubmed/25808056" target="_blank" rel="nofollow"> Komori M, Blake A, Greenwood M et al. Cerebrospinal fluid markers reveal intrathecal inflammation in progressive multiple sclerosis. Ann Neurol 2015-07-01 [PMID: 25808056] (Human) </a></td> <td valign="top"></td> <td valign="top">Human</td> </tr></tbody> </table> </div> </div> <a id="ReviewsSection"></a> <h2 class="greyHead2">Reviews for <span>CD20 Antibody Pair (H00000931-AP22) (0) </span></h2> <div class="ds_info"> There are no reviews for CD20 Antibody Pair (H00000931-AP22). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount. <br/> <ul> <li>Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen</li> <li>Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen</li> </ul> <div class="align-right"> <a href="/reviews/H00000931-AP22"><button class="greybutton btn_width" name="novusreview">Submit a Review</button></a><br /> </div> </div> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_protocols-faqs"> <a id="protocols-faqs"></a><h2 class="greyHead2">FAQs for CD20 Antibody Pair (H00000931-AP22) (0)</h2> <a id="faqs"></a> <div class="ds_info">There are no specific FAQs related to this product. Read our general <a href="/support/faqs.html">customer & technical service FAQs.</a> </div> <div class="clear"></div></div> <div class="ds_tab_content equalbottom" id="content_supportresearch"> <a id="supportresearch"></a><table cellpadding="0" cellspacing="0"><tr></td></tr></table><h2 class="greyHead2">Additional CD20 Products</h2> <a id="addtlalphaprods"></a> <div class="ds_info"> <div> <span style="display:none;">Array H00000931-AP22</span> <ul class="ds_noDotList"><li> <a href="/primary-antibodies/cd20">CD20 Antibodies</a></li><li> <a href="/antibody-pairs/cd20">CD20 Antibody Pair</a></li><li> <a href="/elisa-kits/cd20">CD20 ELISA Kits</a></li><li> <a href="/lysates/cd20">CD20 Lysates</a></li><li> <a href="/proteins/cd20">CD20 Proteins</a></li></ul> </div> </div><table cellpadding="0" cellspacing="0" class="width100"><tr></tr></table><table cellpadding="0" cellspacing="0" class="width100"><tr><td valign="top"><h2 class="greyHead2">Research Areas for CD20 Antibody Pair (H00000931-AP22)</h2> <a id="research_areas"></a> <div class="ds_info">Find related products by research area.</div> <div class="ds_info"> <ul class="ds_noDotList"><li class="left width"><a href="/research-areas/immunology/adaptive-immunity">Adaptive Immunity</a></li><li class="left width"><a href="/research-areas/cancer">Cancer</a></li><li class="left width"><a href="/research-areas/cancer/cancer-stem-cells">Cancer Stem Cells</a></li><li class="left width"><a href="/research-areas/cell-biology">Cell Biology</a></li><li class="left width"><a href="/research-areas/immunology/chemokines-cytokines">Cytokine Research</a></li><li class="left width"><a href="/research-areas/immunology">Immunology</a></li><li class="left width"><a href="/research-areas/signal-transduction">Signal Transduction</a></li><li class="left width"><a href="/research-areas/stem-cell-markers">Stem Cell Markers</a></li><li class="left width"><a href="/research-areas/cancer">Tumor Biomarkers</a></li></ul> </div></td></tr></table><h2 class="greyHead2">Blogs on CD20. </h2> <a id="blogsect"></a> <div class="ds_info"><a href="/antibody-news/tag/cd20">Check out the latest blog posts on CD20</a>.</div> <div class="ds_info"> <table id="blogs_list_table"> <tbody> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/unlocking-the-potential-of-biosimilars-in-immuno-oncology">Unlocking the Potential of Biosimilars in Immuno-Oncology</a></strong><br/> <span> By Jennifer Jones, M.S.Biosimilar Antibodies: Imitation Meets InnovationIn the ever-evolving medical landscape, a new class of pharmaceuticals is emerging as a game-changer, poised to transform the way we approach...  <a href="/antibody-news/unlocking-the-potential-of-biosimilars-in-immuno-oncology">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/antigen-loss-relapse-after-successful-car-t-therapy-what-do-we-do-now">Antigen-loss relapse after successful CAR-T therapy; What do we do now?</a></strong><br/> <span> By Jacqueline Carrico, BS, MD Tumor cell mechanisms driving tolerance to CAR-T Despite very promising results of CAR-T therapy in acute lymphoblastic leukemia, B-ALL, antigen-loss relapse has arisen as a major chall...  <a href="/antibody-news/antigen-loss-relapse-after-successful-car-t-therapy-what-do-we-do-now">Read full blog post.</a></span><br /><br /> </td> </tr> <tr class=" blogwrap "> <td> <strong><a href="/antibody-news/antibodies/cd20-cluster-of-differentiation-20-membrane-spanning-4-domains-subfamily-a-member-1-ms4a1-cvid5-b-lymphocyte-surface-antigen-b1">CD20 (Cluster of differentiation 20, Membrane-spanning 4-domains subfamily A member 1 (MS4A1), CVID5, B-lymphocyte surface antigen B1)</a></strong><br/> <span>CD20 is a human B-lymphocyte surface molecule that spans the membrane four times and is expressed on both normal and malignant cells. The CD20 antigen displays a unique expression pattern among hematopoietic cells - it is present on human pre B-ly...  <a href="/antibody-news/antibodies/cd20-cluster-of-differentiation-20-membrane-spanning-4-domains-subfamily-a-member-1-ms4a1-cvid5-b-lymphocyte-surface-antigen-b1">Read full blog post.</a></span><br /><br /> </td> </tr></tbody> </table> </div> <div class="clear"></div></div> </div></div><div class="grid_6"><div class="ds_blue_border marTop26 equalbottom"><div class="datasheet-ads-container" ><a href="https://www.bio-techne.com/resources/blogs/citation-widget-find-products-used-in-literature" target="_blank"><img loading="lazy" src="https://images.novusbio.com/design/citation-app-banner-349x119-v3.jpg" alt="Read our latest blog and use the new citation tool on bio-techne.com" title="new citation tool" class="datasheet-adzone" loading="lazy"></a></div><a id="jump_recommended"></a> <h2 class="greyHead2">Customers Who Bought This Also Bought</h2> <div class="text_center"><div class="images2"><div id="ss_prev_sidebar" class="cycle-prev ds_rp_prev"><div class="pager_left_on"></div></div><div id="ss_next_sidebar" class="cycle-next ds_rp_next"><div class="pager_right_on"></div></div><div class="cycle-slideshow" data-cycle-fx="scrollHorz" data-cycle-timeout="0" data-cycle-prev="#ss_prev_sidebar" data-cycle-next="#ss_next_sidebar" data-cycle-slides="div.big_thumb_container" id="ds_customer_who_bought" ><div class="big_thumb_container" data-catnums="210-TA-005"> <div class="img_container"> <a href="/products/recombinant-human-tnf-alpha-protein_210-ta" title="1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa." class="cust_bought" > <img loading="lazy" src="https://images.novusbio.com/images2/TNF-alpha_210-TA_256.jpg" title="1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa." alt="1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa." class="big_thumb" /> </a> </div> <div class="caption_container"><a href="/products/recombinant-human-tnf-alpha-protein_210-ta">TNF-alpha [Unconjugated]</a> <br />210-TA-005</div> <div style="text-align: right"><button class="greybutton" id="novusviewdatasheet" name="novusviewdatasheet" onclick="window.location='/products/recombinant-human-tnf-alpha-protein_210-ta';" >View Datasheet</button> </div> </div><div class="big_thumb_container" data-catnums="AF114"> <div class="img_container"> <a href="/products/cd45-antibody_af114" title=" CD45 was detected in immersion fixed paraffin-embedded sections of mouse liver using Goat Anti-Mouse CD45 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF114) at 3&nbsp;µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte&#8482; HRP Polymer Antibody (Catalog&nbsp;# VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to Kupffer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="cust_bought" > <img loading="lazy" src="https://images.novusbio.com/images2/CD45_AF114_Immunohistochemistry_23525.jpg" title=" CD45 was detected in immersion fixed paraffin-embedded sections of mouse liver using Goat Anti-Mouse CD45 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF114) at 3&nbsp;µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte&#8482; HRP Polymer Antibody (Catalog&nbsp;# VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to Kupffer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." alt=" CD45 was detected in immersion fixed paraffin-embedded sections of mouse liver using Goat Anti-Mouse CD45 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF114) at 3&nbsp;µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte&#8482; HRP Polymer Antibody (Catalog&nbsp;# VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to Kupffer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_thumb" /> </a> </div> <div class="caption_container"><a href="/products/cd45-antibody_af114">CD45 Antibody [Unconjugated]</a> <br />AF114</div> <div style="text-align: right"><button class="greybutton" id="novusviewdatasheet" name="novusviewdatasheet" onclick="window.location='/products/cd45-antibody_af114';" >View Datasheet</button> </div> </div></div></div></div><div class="clear"></div><a id="jump_distributor"></a> <h2 class="greyHead2">Contact Information</h2> <div class="ds_info"> <div id="distributors"></div> </div> <div id="et_reload_trigger" style="display:none;">reload</div><h2 class="greyHead2">Product PDFs</h2><div class="silverHeadShort"> <span class="file"><a href="//www.novusbio.com/PDFs/H00000931-AP22.pdf" target="_blank" class="sprite_dsPDF"><span class="pdfSmaller"> </span></a></span> <span class="download-file-text" ><a href="//www.novusbio.com/PDFs/H00000931-AP22.pdf" target="_blank" class="datasheet-download">PDF Datasheet</a></span> </div><div class="silverHeadShort"> <span class="file"><a href="mailto:novus@novusbio.com?subject=Request%20CofA%20for%20H00000931-AP22" class="sprite_newDocument"><span class="downloadBlank"> </span></a></span> <span class="download-file-text"><a href="mailto:nb-technical@bio-techne.com?subject=Request%20CofA%20for%20H00000931-AP22&body=Specific%20catalog%20number(if multiple sizes):%0ALot%20Number:%0AAny%20additional%20products:">Request CofA</a></span> </div><div class="silverHeadShort"> <span class="file"><a href="mailto:novus@novusbio.com?subject=Request%20MSDS%20for%20H00000931-AP22" class="sprite_newDocument"><span class="downloadBlank"> </span></a></span> <span class="download-file-text"><a href="mailto:nb-technical@bio-techne.com?subject=Request%20MSDS%20for%20H00000931-AP22&body=Specific%20catalog%20number(if multiple sizes):%0AAny%20additional%20products:">Request SDS</a></span> </div><h2 class="greyHead2">Review this Product</h2> <div style="padding:10px;"> Be the first to review our CD20 Antibody Pair and receive a gift card or discount.<br /><br /> <div class="text_center"> <div class="dsSprite_stars5" style="position:relative;top:3px;"></div> <a href="/reviews/H00000931-AP22"><button class="greybutton btn_width" name="novusreview">Submit a Review</button></a><br /> </div> </div><h2 class="greyHead2">Bioinformatics</h2> <div class="ds_info"> <a id="tab1bioinformatics"></a> <div> <table class="ds_list_right wide top"> <tr class="lined"> <td><strong>Gene Symbol</strong></td> <td><a href="/gene-name/MS4A1">MS4A1</a></td> </tr></table> </div> </div> </div> </div><div class="clear"></div> </div> </div> <div id="block-block-21" class="block block-block"> <div class="content">  <div class="embeddedServiceInvitation" id="snapins_invite" aria-live="assertive" role="dialog" aria-atomic="true" style="display: none;"> <div class="embeddedServiceInvitationHeader" aria-labelledby="snapins_titletext" aria-describedby="snapins_bodytext"> <img id="embeddedServiceAvatar" /> <span class="embeddedServiceTitleText" id="snapins_titletext">Need help?</span> <button type="button" id="closeInvite" class="embeddedServiceCloseIcon" aria-label="Exit invitation">×</button> </div> <div class="embeddedServiceInvitationBody"> <p id="snapins_bodytext">How can we help you?</p> </div> <div class="embeddedServiceInvitationFooter" aria-describedby="snapins_bodytext"> <button type="button" class="embeddedServiceActionButton" id="rejectInvite">Close</button> <button type="button" class="embeddedServiceActionButton" id="acceptInvite">Start Chat</button> </div> </div> </div> </div> </div> </div> </div> <div id="novus_footer_line"></div>  </div> <div class="container_16"> <div id="footer"> <div class="grid_16 text_center"> <div class="fp_horzline"></div> </div> <div class="clear"></div> <div class="grid_16"> <table class="footer_boxes"> <tr> <th>Popular Products</th> <th>Company Information</th> <th>Support</th> <th>Stay Connected</th> </tr> <tr> <td> <ul class='links'><li><a href="/productsearch/novus">Antibodies</a></li><li><a href="/product-type/secondary-antibodies">Secondary Antibodies</a></li><li><a href="/product-type/isotype-controls">Isotype Controls</a></li><li><a href="/product-type/peptides-and-proteins">Proteins and Peptides</a></li><li><a href="/product-type/elisa-kits">ELISA Kits</a></li><li><a href="/samplesize">Sample Size</a></li><li><a href="https://www.novusbio.com/new-product-information-page.html">New Products</a></li> </ul> </td> <td> <ul class='links'><li><a href="/about.html">About Us</a></li><li><a href="https://www.bio-techne.com/about/careers">Careers</a></li><li><a href="/guarantee">Novus Guarantee</a></li><li><a href="/about/contact-us.html">Contact Us</a></li><li><a href="/about/novus-team.html">Our Team</a></li> </ul> </td> <td> <ul class='links'><li><a href="/support/technical-support.html">Technical Support</a></li><li><a href="/support/faqs.html">FAQs</a></li><li><a href="/webform/help-finding-antibodies">Help Finding Antibodies</a></li><li><a href="/support/support-by-application.html">Protocols</a></li> </ul> </td> <td id="footer_social_links"> </td> </tr> </table> </div> <div class="clear"></div> <div class="grid_16"> <div id="GTS_CONTAINER" style="float: right;margin-top: 10px;"></div> <div id="footer_officeinfo"> </div> <div class="fp_horzline"></div> <div class="footer_othersites"> <p>Visit our other sites</p> <a href="https://www.bio-techne.com/" target="_blank"><div class="fp_biotechne"></div></a> <a href="https://www.rndsystems.com/"><div class="fp_rnd"></div></a> <a href="https://www.novusbio.com/" target="_blank"><div class="fp_novus"></div></a> <a href="https://www.tocris.com/" target="_blank"><div class="fp_tocris"></div></a> <a href="https://www.bio-techne.com/brands/proteinsimple" target="_blank"><div class="fp_proteinSimple"></div></a> <a href="http://www.biospacific.com/" target="_blank"><div class="fp_biospacific"></div></a>  <a href="http://www.acdbio.com/" target="_blank"><div class="fp_acd"></div></a> <a href="https://www.rndheme.com/" target="_blank"><div class="fp_rndcc"></div></a> </div> <div class="text_center"> <div class="fp_horzline"></div> </div> <div class="copyright">©2024 Novus Biologicals, All Rights Reserved.</div> <div class="footer_legal"> <ul class="links"><li class="menu-47946 first"><a href="/support/customer-service/privacy-policy.html" title="">Privacy Policy</a></li> <li class="menu-47956"><a href="/novus-bio-sitemap.html" title="">Sitemap</a></li> <li class="menu-47951"><a href="/about/contact-us.html" title="">Contact Us</a></li> <li class="menu-47941 last"><a href="/support/customer-service/terms.html" title="">Terms & Conditions</a></li> </ul> </div> <div class="clear"></div> </div> </div> </div> <script type="text/javascript"> <![CDATA[//><!]]> </script> <script type="text/javascript">window.NREUM||(NREUM={});NREUM.info={"beacon":"bam.nr-data.net","licenseKey":"76fb58fb05","applicationID":"788348554,30870807","transactionName":"YFdbZBFZXxdWAhAMVlkdeFMXUV4KGAYBC1xFU01VPFxQEFYSDABcQw==","queueTime":35,"applicationTime":791,"atts":"TBBYEllDTBk=","errorBeacon":"bam.nr-data.net","agent":""}</script></body> </html>

CINXE.COM

CD20 Antibody Pair (H00000931-AP22): Novus Biologicals