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<span>Demain</span> </div> </a> <ul id="toc-Demain-sublist" class="vector-toc-list"> <li id="toc-Thérapie_génique" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Thérapie_génique"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2.1</span> <span>Thérapie génique</span> </div> </a> <ul id="toc-Thérapie_génique-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Régénération_des_cellules_altérées_par_des_cellules_souches" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Régénération_des_cellules_altérées_par_des_cellules_souches"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2.2</span> <span>Régénération des cellules altérées par des cellules souches</span> </div> </a> <ul id="toc-Régénération_des_cellules_altérées_par_des_cellules_souches-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> </ul> </li> <li id="toc-Articles_connexes" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Articles_connexes"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Articles connexes</span> </div> </a> <ul id="toc-Articles_connexes-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Notes_et_références" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Notes_et_références"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Notes et références</span> </div> </a> <ul id="toc-Notes_et_références-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Sommaire" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Basculer la table des matières" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Basculer la table des matières</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Surdité de perception</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Aller à un article dans une autre langue. Disponible en 14 langues." > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-14" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">14 langues</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%B5%D9%85%D9%85_%D8%AD%D8%B3%D9%8A_%D8%B9%D8%B5%D8%A8%D9%8A" title="صمم حسي عصبي – arabe" lang="ar" hreflang="ar" data-title="صمم حسي عصبي" data-language-autonym="العربية" data-language-local-name="arabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/H%C3%B6rsturz" title="Hörsturz – allemand" lang="de" hreflang="de" data-title="Hörsturz" data-language-autonym="Deutsch" data-language-local-name="allemand" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Sensorineural_hearing_loss" title="Sensorineural hearing loss – anglais" lang="en" hreflang="en" data-title="Sensorineural hearing loss" data-language-autonym="English" data-language-local-name="anglais" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/P%C3%A9rdida_de_audici%C3%B3n" title="Pérdida de audición – espagnol" lang="es" hreflang="es" data-title="Pérdida de audición" data-language-autonym="Español" data-language-local-name="espagnol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%DA%A9%D8%A7%D9%87%D8%B4_%D8%B4%D9%86%D9%88%D8%A7%DB%8C%DB%8C_%D8%AD%D8%B3%DB%8C_-_%D8%B9%D8%B5%D8%A8%DB%8C" title="کاهش شنوایی حسی - عصبی – persan" lang="fa" hreflang="fa" data-title="کاهش شنوایی حسی - عصبی" data-language-autonym="فارسی" data-language-local-name="persan" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%9C%E0%A5%8D%E0%A4%9E%E0%A4%BE%E0%A4%A8%E0%A5%87%E0%A4%A8%E0%A5%8D%E0%A4%A6%E0%A5%8D%E0%A4%B0%E0%A5%80%E0%A4%AF-%E0%A4%A4%E0%A4%82%E0%A4%A4%E0%A5%8D%E0%A4%B0%E0%A4%BF%E0%A4%95%E0%A4%BE%E0%A4%AF_%E0%A4%AC%E0%A4%A7%E0%A4%BF%E0%A4%B0%E0%A4%A4%E0%A4%BE" title="ज्ञानेन्द्रीय-तंत्रिकाय बधिरता – hindi" lang="hi" hreflang="hi" data-title="ज्ञानेन्द्रीय-तंत्रिकाय बधिरता" data-language-autonym="हिन्दी" data-language-local-name="hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Ipoacusia" title="Ipoacusia – italien" lang="it" hreflang="it" data-title="Ipoacusia" data-language-autonym="Italiano" data-language-local-name="italien" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EA%B0%90%EA%B0%81_%EC%8B%A0%EA%B2%BD%EC%84%B1_%EB%82%9C%EC%B2%AD" title="감각 신경성 난청 – coréen" lang="ko" hreflang="ko" data-title="감각 신경성 난청" data-language-autonym="한국어" data-language-local-name="coréen" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Perceptiedoofheid" title="Perceptiedoofheid – néerlandais" lang="nl" hreflang="nl" data-title="Perceptiedoofheid" data-language-autonym="Nederlands" data-language-local-name="néerlandais" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Perda_auditiva_neurossensorial" title="Perda auditiva neurossensorial – portugais" lang="pt" hreflang="pt" data-title="Perda auditiva neurossensorial" data-language-autonym="Português" data-language-local-name="portugais" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9D%D0%B5%D0%B9%D1%80%D0%BE%D1%81%D0%B5%D0%BD%D1%81%D0%BE%D1%80%D0%BD%D0%B0%D1%8F_%D1%82%D1%83%D0%B3%D0%BE%D1%83%D1%85%D0%BE%D1%81%D1%82%D1%8C" title="Нейросенсорная тугоухость – russe" lang="ru" hreflang="ru" data-title="Нейросенсорная тугоухость" data-language-autonym="Русский" data-language-local-name="russe" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Sensorineural_hearing_loss" title="Sensorineural hearing loss – Simple English" lang="en-simple" hreflang="en-simple" data-title="Sensorineural hearing loss" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-tt mw-list-item"><a href="https://tt.wikipedia.org/wiki/%D0%9D%D0%B5%D0%B9%D1%80%D0%BE%D1%81%D0%B5%D0%BD%D1%81%D0%BE%D1%80%D0%BB%D1%8B_%D1%81%D0%B0%D2%A3%D0%B3%D1%8B%D1%80%D0%B0%D1%83%D0%BB%D1%8B%D0%BA" title="Нейросенсорлы саңгыраулык – tatar" lang="tt" hreflang="tt" data-title="Нейросенсорлы саңгыраулык" data-language-autonym="Татарча / tatarça" data-language-local-name="tatar" class="interlanguage-link-target"><span>Татарча / tatarça</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E6%84%9F%E8%A7%89%E7%A5%9E%E7%BB%8F%E6%80%A7%E8%80%B3%E8%81%8B" title="感觉神经性耳聋 – chinois" lang="zh" hreflang="zh" data-title="感觉神经性耳聋" data-language-autonym="中文" data-language-local-name="chinois" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q928697#sitelinks-wikipedia" title="Modifier les liens interlangues" class="wbc-editpage">Modifier les liens</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Espaces de noms"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Surdit%C3%A9_de_perception" title="Voir le contenu de la page [c]" accesskey="c"><span>Article</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Discussion:Surdit%C3%A9_de_perception" rel="discussion" title="Discussion au sujet de cette page de contenu [t]" accesskey="t"><span>Discussion</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Modifier la variante de langue" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">français</span> </label> <div 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</ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> Général </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Sp%C3%A9cial:Pages_li%C3%A9es/Surdit%C3%A9_de_perception" title="Liste des pages liées qui pointent sur celle-ci [j]" accesskey="j"><span>Pages liées</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Sp%C3%A9cial:Suivi_des_liens/Surdit%C3%A9_de_perception" rel="nofollow" title="Liste des modifications récentes des pages appelées par celle-ci [k]" accesskey="k"><span>Suivi des pages liées</span></a></li><li id="t-upload" class="mw-list-item"><a href="/wiki/Aide:Importer_un_fichier" title="Téléverser des fichiers [u]" accesskey="u"><span>Téléverser un fichier</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Sp%C3%A9cial:Pages_sp%C3%A9ciales" title="Liste de toutes les 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data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Un article de Wikipédia, l'encyclopédie libre.</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="fr" dir="ltr"><div class="infobox_v3 infobox infobox--frwiki noarchive large" style="width:22em"> <div class="entete icon defaut" style="background-color: lightgrey; color: #000000;"> <div>Surdité de perception</div> </div> <div class="images"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/Fichier:Audiograma_representando_perda_auditiva_sens%C3%B3rioneural.png" class="mw-file-description"><img alt="Description de l'image Audiograma representando perda auditiva sensórioneural.png." src="//upload.wikimedia.org/wikipedia/commons/thumb/4/49/Audiograma_representando_perda_auditiva_sens%C3%B3rioneural.png/260px-Audiograma_representando_perda_auditiva_sens%C3%B3rioneural.png" decoding="async" width="260" height="195" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/49/Audiograma_representando_perda_auditiva_sens%C3%B3rioneural.png/390px-Audiograma_representando_perda_auditiva_sens%C3%B3rioneural.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/49/Audiograma_representando_perda_auditiva_sens%C3%B3rioneural.png/520px-Audiograma_representando_perda_auditiva_sens%C3%B3rioneural.png 2x" data-file-width="3170" data-file-height="2376" /></a></span> </div> <table><caption class="hidden" style="">Données clés</caption> </table><p class="mw-empty-elt"> </p><table><caption style="background-color:lightgrey;">Traitement</caption> <tbody><tr> <th scope="row"><a href="/wiki/Sp%C3%A9cialit%C3%A9_m%C3%A9dicale" title="Spécialité médicale">Spécialité</a></th> <td> <span class="wd_p1995"><a href="/wiki/Otorhinolaryngologie" title="Otorhinolaryngologie">Otorhinolaryngologie</a><span class="noprint wikidata-linkback skin-invert"><span class="mw-valign-baseline noviewer" typeof="mw:File"><a href="https://www.wikidata.org/wiki/Q928697?uselang=fr#P1995" title="Voir et modifier les données sur Wikidata"><img alt="Voir et modifier les données sur Wikidata" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/10px-Blue_pencil.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/15px-Blue_pencil.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/73/Blue_pencil.svg/20px-Blue_pencil.svg.png 2x" data-file-width="600" data-file-height="600" /></a></span></span></span></td> </tr> </tbody></table> <table><caption style="background-color:lightgrey;">Classification et ressources externes</caption> <tbody><tr> <th scope="row"><a href="/wiki/H%C3%A9ritage_mend%C3%A9lien_chez_l%27humain" title="Héritage mendélien chez l'humain">OMIM</a></th> <td> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/omim/304400">304400</a></td> </tr> <tr> <th scope="row">DiseasesDB</th> <td> <a rel="nofollow" class="external text" href="http://www.diseasesdatabase.com/ddb2874.htm">2874</a></td> </tr> <tr> <th scope="row"><a href="/wiki/MedlinePlus" title="MedlinePlus">MedlinePlus</a></th> <td> <a rel="nofollow" class="external text" href="https://www.nlm.nih.gov/medlineplus/ency/article/003291.htm">003291</a></td> </tr> <tr> <th scope="row"><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a></th> <td> <a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=D006319">D006319</a></td> </tr> </tbody></table> <p class="bloc" style="background-color:lightgrey; color:#FFFFFF;"><span typeof="mw:File"><a href="/wiki/Wikip%C3%A9dia:Mise_en_garde_m%C3%A9dicale" title="Wikipédia ne donne pas de conseils médicaux"><img alt="Wikipédia ne donne pas de conseils médicaux" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d5/Star_of_life_caution.svg/24px-Star_of_life_caution.svg.png" decoding="async" width="24" height="22" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d5/Star_of_life_caution.svg/36px-Star_of_life_caution.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d5/Star_of_life_caution.svg/48px-Star_of_life_caution.svg.png 2x" data-file-width="210" data-file-height="190" /></a></span> <a href="/wiki/Wikip%C3%A9dia:Mise_en_garde_m%C3%A9dicale" title="Wikipédia:Mise en garde médicale">Mise en garde médicale</a></p> <p class="navbar bordered noprint" style="border-color:lightgrey;"><span class="plainlinks"><a class="external text" href="https://fr.wikipedia.org/w/index.php?title=Surdit%C3%A9_de_perception&veaction=edit&section=0">modifier</a> - <a class="external text" href="https://fr.wikipedia.org/w/index.php?title=Surdit%C3%A9_de_perception&action=edit&section=0">modifier le code</a> - <a href="https://www.wikidata.org/wiki/Special:ItemByTitle/frwiki/Surdit%C3%A9_de_perception" class="extiw" title="d:Special:ItemByTitle/frwiki/Surdité de perception">voir Wikidata</a> <a href="/wiki/Aide:Infobox_Wikidata" title="Aide:Infobox Wikidata">(aide)</a></span> <span typeof="mw:File"><a href="/wiki/Mod%C3%A8le:Infobox_Maladie" title="Consultez la documentation du modèle"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/12px-Info_Simple.svg.png" decoding="async" width="12" height="12" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/18px-Info_Simple.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/38/Info_Simple.svg/24px-Info_Simple.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></p></div> <p>La <b>surdité de perception</b> est intrinsèquement consécutive à des lésions nerveuses et de certaines cellules ciliées de l'oreille interne. Lorsque les cellules ciliées et les neurones sont détériorés ou détruits, ils ne régénèrent pas naturellement et entraînent des déficits auditifs irréversibles. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Origine_des_lésions"><span id="Origine_des_l.C3.A9sions"></span>Origine des lésions</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&veaction=edit&section=1" title="Modifier la section : Origine des lésions" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&action=edit&section=1" title="Modifier le code source de la section : Origine des lésions"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>À peu près toutes les cellules de l’oreille interne proviennent de la placode otique, qui réunit un ensemble de cellules identiques lors du développement de l'embryon. </p> <div class="mw-heading mw-heading2"><h2 id="Traitements">Traitements</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&veaction=edit&section=2" title="Modifier la section : Traitements" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&action=edit&section=2" title="Modifier le code source de la section : Traitements"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Si la <a href="/wiki/Surdit%C3%A9_de_transmission" class="mw-redirect" title="Surdité de transmission">surdité de transmission</a> ne peut excéder 60 <abbr class="abbr" title="décibel">dB</abbr> et se compense aujourd'hui assez couramment et assez aisément (réparation par <a href="/wiki/Stap%C3%A9dectomie" title="Stapédectomie">stapédectomie</a> pour l'<a href="/wiki/Otospongiose" title="Otospongiose">otospongiose</a>, contournement par <a href="/wiki/BAHA" class="mw-redirect" title="BAHA">BAHA</a>, compensation par une <a href="/wiki/Audioproth%C3%A8se" title="Audioprothèse">audioprothèse</a>), la surdité de perception (oreille interne et système nerveux) ne se traite pas ou mal avec une opération chirurgicale, car il s'agit de systèmes très complexes, notamment des cellules ciliées de la <a href="/wiki/Cochl%C3%A9e" class="mw-redirect" title="Cochlée">cochlée</a>. </p> <div class="mw-heading mw-heading3"><h3 id="Aujourd'hui"><span id="Aujourd.27hui"></span>Aujourd'hui</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&veaction=edit&section=3" title="Modifier la section : Aujourd'hui" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&action=edit&section=3" title="Modifier le code source de la section : Aujourd'hui"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Si aujourd'hui des opérations sont proposées à la surdité de perception, notamment l'<a href="/wiki/Implant_cochl%C3%A9aire" title="Implant cochléaire">implant cochléaire</a> et l'<a href="/wiki/Implant_du_tronc_c%C3%A9r%C3%A9bral" title="Implant du tronc cérébral">implant du tronc cérébral</a>, il faudra encore attendre plusieurs années pour voir des résultats probants. </p> <div class="mw-heading mw-heading3"><h3 id="Demain">Demain</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&veaction=edit&section=4" title="Modifier la section : Demain" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&action=edit&section=4" title="Modifier le code source de la section : Demain"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>La thérapie génique et la recherche sur les cellules souches, d'autres pistes de recherche sont poursuivies, notamment la thérapie génique et la régénération des cellules altérées<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite_crochet">[</span>1<span class="cite_crochet">]</span></a></sup> par des cellules souches. </p> <div class="mw-heading mw-heading4"><h4 id="Thérapie_génique"><span id="Th.C3.A9rapie_g.C3.A9nique"></span>Thérapie génique</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&veaction=edit&section=5" title="Modifier la section : Thérapie génique" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&action=edit&section=5" title="Modifier le code source de la section : Thérapie génique"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Selon John Brigande, ORL à la Faculté des sciences de Portland dans l’Oregon, il est désormais possible de produire des cellules ciliées dans la cochlée des souris cobayes. Le gène « Atoh 1″ fut transféré par l’entremise d’un virus inoffensif et a favorisé l’apparition cellules ciliées à l’état post natal. </p><p>En étudiant des souris cobayes en qui le gène FGF20 a été inactivé<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite_crochet">[</span>2<span class="cite_crochet">]</span></a></sup>, des biologistes américains, dont <abbr class="abbr" title="Professeur">P<sup>r</sup></abbr> David M. Ornitz, de la <i><span class="lang-en" lang="en">Washington University School of Medicine</span></i>, ont constaté également que des mutations du gène FGF20 peuvent jouer un rôle dans la surdité humaine<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite_crochet">[</span>3<span class="cite_crochet">]</span></a></sup>. La surdité, héréditaire, pourrait donc être liée à une mutation dans le gène FGF20<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite_crochet">[</span>4<span class="cite_crochet">]</span></a></sup><sup class="reference cite_virgule">,</sup><sup id="cite_ref-plos-biol2012_5-0" class="reference"><a href="#cite_note-plos-biol2012-5"><span class="cite_crochet">[</span>5<span class="cite_crochet">]</span></a></sup>. </p><p>L'exposition des <a href="/wiki/Travailleur" title="Travailleur">travailleurs</a> à un <a href="/wiki/Bruit_au_travail" title="Bruit au travail">bruit</a> fort crée un risque auditif. Ils doivent donc utiliser des équipements de <a href="/wiki/Protection_auditive" title="Protection auditive">protection individuelle</a>. Mais la recherche scientifique a montré qu'ils sont inefficaces<sup id="cite_ref-AIHA-6-11_6-0" class="reference"><a href="#cite_note-AIHA-6-11-6"><span class="cite_crochet">[</span>6<span class="cite_crochet">]</span></a></sup><sup class="reference cite_virgule">,</sup><sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite_crochet">[</span>7<span class="cite_crochet">]</span></a></sup>. </p> <div class="mw-heading mw-heading4"><h4 id="Régénération_des_cellules_altérées_par_des_cellules_souches"><span id="R.C3.A9g.C3.A9n.C3.A9ration_des_cellules_alt.C3.A9r.C3.A9es_par_des_cellules_souches"></span>Régénération des cellules altérées par des cellules souches</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&veaction=edit&section=6" title="Modifier la section : Régénération des cellules altérées par des cellules souches" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&action=edit&section=6" title="Modifier le code source de la section : Régénération des cellules altérées par des cellules souches"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="bandeau-container bandeau-section metadata bandeau-niveau-information"><div class="bandeau-cell bandeau-icone"><span class="mw-valign-text-top noviewer" typeof="mw:File"><a href="/wiki/Fichier:Fairytale_warning.png" class="mw-file-description"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/87/Fairytale_warning.png/17px-Fairytale_warning.png" decoding="async" width="17" height="17" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/87/Fairytale_warning.png/26px-Fairytale_warning.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/87/Fairytale_warning.png/34px-Fairytale_warning.png 2x" data-file-width="64" data-file-height="64" /></a></span></div><div class="bandeau-cell">Cette section est vide, insuffisamment détaillée ou incomplète. <a href="/wiki/Sp%C3%A9cial:EditPage/Surdit%C3%A9_de_perception" title="Spécial:EditPage/Surdité de perception">Votre aide</a> est la bienvenue ! <a href="/wiki/Aide:Comment_modifier_une_page" title="Aide:Comment modifier une page">Comment faire ?</a></div></div> <div class="mw-heading mw-heading2"><h2 id="Articles_connexes">Articles connexes</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&veaction=edit&section=7" title="Modifier la section : Articles connexes" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&action=edit&section=7" title="Modifier le code source de la section : Articles connexes"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Acoum%C3%A9trie" title="Acoumétrie">acoumétrie</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Notes_et_références"><span id="Notes_et_r.C3.A9f.C3.A9rences"></span>Notes et références</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&veaction=edit&section=8" title="Modifier la section : Notes et références" class="mw-editsection-visualeditor"><span>modifier</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Surdit%C3%A9_de_perception&action=edit&section=8" title="Modifier le code source de la section : Notes et références"><span>modifier le code</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="references-small decimal" style=""><div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink noprint"><a href="#cite_ref-1">↑</a> </span><span class="reference-text"> Inserm - U583 / <a rel="nofollow" class="external text" href="http://www.univ-montp1.fr/recherche/unites_de_recherche/physiopathologie_et_therapie_des_deficits_sensoriels_et_moteurs_institut_des_neurosciences_de_montpellier">INM - Physiopathologie et thérapie des déficits sensoriels et moteurs</a></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink noprint"><a href="#cite_ref-2">↑</a> </span><span class="reference-text"> P. Bernanose « Découverte d'un gène de l'amplification » <i>www.santelog.com</i>, 5 janvier 2012.</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink noprint"><a href="#cite_ref-3">↑</a> </span><span class="reference-text"> Alain Tranet « Surdité : des généticiens ont franchi une étape importante dans sa compréhension » <i>www.journaldelascience.fr</i>, jeudi 5 janvier 2012.</span> </li> <li id="cite_note-4"><span class="mw-cite-backlink noprint"><a href="#cite_ref-4">↑</a> </span><span class="reference-text"> G.F. « Identification d'un gène intervenant dans le développement de l'oreille interne », <i>www.audiology-infos.eu</i>, 6 janvier 2012.</span> </li> <li id="cite_note-plos-biol2012-5"><span class="mw-cite-backlink noprint"><a href="#cite_ref-plos-biol2012_5-0">↑</a> </span><span class="reference-text"> <abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Huh SH, Jones J, Warchol ME, Ornitz DM. <a rel="nofollow" class="external text" href="http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001231">« Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal »</a> <i>PLoS Biol.</i> 2012;10(1):e1001231. <span class="reflink plainlinksneverexpand"><a href="/wiki/PMID" class="mw-redirect" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/22235191">22235191</a></span> <small class="plainlinks noarchive"><a href="/wiki/Digital_Object_Identifier" title="Digital Object Identifier">DOI</a> <a rel="nofollow" class="external text" href="https://dx.doi.org/10.1371%2Fjournal.pbio.1001231">10.1371/journal.pbio.1001231</a></small></span> </li> <li id="cite_note-AIHA-6-11-6"><span class="mw-cite-backlink noprint"><a href="#cite_ref-AIHA-6-11_6-0">↑</a> </span><span class="reference-text"><span class="ouvrage" id="BergerVoix2018"><span class="ouvrage" id="Elliott_H._BergerJérémie_Voix2018"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> Elliott H. <span class="nom_auteur">Berger</span> et Jérémie <span class="nom_auteur">Voix</span>, <cite class="italique" lang="en">The Noise Manual (éditeurs D.K. Meinke, E.H. Berger, R. Neitzel, D.P. Driscoll, K. Bright)</cite>, Falls Church, Virginia, American Industrial Hygiene Association, <time>2018</time>, 6th <abbr class="abbr" title="édition">éd.</abbr>, 621 <abbr class="abbr" title="pages">p.</abbr> <small style="line-height:1em;">(<a href="/wiki/International_Standard_Book_Number" title="International Standard Book Number">ISBN</a> <a href="/wiki/Sp%C3%A9cial:Ouvrages_de_r%C3%A9f%C3%A9rence/978-1-950286-07-2" title="Spécial:Ouvrages de référence/978-1-950286-07-2"><span class="nowrap">978-1-950286-07-2</span></a>, <a rel="nofollow" class="external text" href="https://online-ams.aiha.org/amsssa/ecssashop.show_product_detail?p_mode=detail&p_product_serno=2719">lire en ligne</a> <abbr class="abbr indicateur-format format-pdf" title="Document au format Portable Document Format (PDF) d'Adobe">[PDF]</abbr>)</small><span class="lang-en" lang="en">, « Chapter 11: Hearing Protection Devices »</span>, <abbr class="abbr" title="pages">p.</abbr> <span class="nowrap">255–308</span><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=The+Noise+Manual+%28%C3%A9diteurs+D.K.+Meinke%2C+E.H.+Berger%2C+R.+Neitzel%2C+D.P.+Driscoll%2C+K.+Bright%29&rft.place=Falls+Church%2C+Virginia&rft.pub=American+Industrial+Hygiene+Association&rft.edition=6th&rft.aulast=Berger&rft.aufirst=Elliott+H.&rft.au=Voix%2C+J%C3%A9r%C3%A9mie&rft.date=2018&rft.pages=255%E2%80%93308&rft.tpages=621&rft.isbn=978-1-950286-07-2&rfr_id=info%3Asid%2Ffr.wikipedia.org%3ASurdit%C3%A9+de+perception"></span></span></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink noprint"><a href="#cite_ref-7">↑</a> </span><span class="reference-text"><span class="ouvrage" id="GroenewoldMastersonThemannDavis2014"><span class="ouvrage" id="M.R._GroenewoldC.L._MastersonThemannR.R._Davis2014"><abbr class="abbr indicateur-langue" title="Langue : anglais">(en)</abbr> M.R. <span class="nom_auteur">Groenewold</span>, C.L. <span class="nom_auteur">Masterson</span>, <span class="nom_auteur">Themann</span> et R.R. <span class="nom_auteur">Davis</span>, « <cite style="font-style:normal" lang="en">Do hearing protectors protect hearing?</cite> », <i><span class="lang-en" lang="en">American Journal of Industrial Medicine</span></i>, Wiley Periodicals, <abbr class="abbr" title="volume">vol.</abbr> 57, <abbr class="abbr" title="numéro">n<sup>o</sup></abbr> 9,‎ <time class="nowrap" datetime="2014-04-03" data-sort-value="2014-04-03">3 avril 2014</time>, <abbr class="abbr" title="pages">p.</abbr> <span class="nowrap">1001-1010</span> <small style="line-height:1em;">(<a href="/wiki/International_Standard_Serial_Number" title="International Standard Serial Number">ISSN</a> <span class="plainlinks noarchive"><a rel="nofollow" class="external text" href="https://portal.issn.org/resource/issn/1097-0274">1097-0274</a></span>, <a href="/wiki/PubMed" title="PubMed">PMID</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmed/24700499">24700499</a></span>, <a href="/wiki/Digital_Object_Identifier" title="Digital Object Identifier">DOI</a> <span class="plainlinks noarchive nowrap"><a rel="nofollow" class="external text" href="https://dx.doi.org/10.1002/ajim.22323">10.1002/ajim.22323</a></span>, <a rel="nofollow" class="external text" href="https://stacks.cdc.gov/view/cdc/36768">lire en ligne</a>)</small><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Do+hearing+protectors+protect+hearing%3F&rft.jtitle=American+Journal+of+Industrial+Medicine&rft.issue=9&rft.aulast=Groenewold&rft.aufirst=M.R.&rft.au=Masterson%2C+C.L.&rft.au=Themann&rft.au=Davis%2C+R.R.&rft.date=2014-04-03&rft.volume=57&rft.pages=1001-1010&rft_id=info%3Adoi%2F10.1002%2Fajim.22323&rfr_id=info%3Asid%2Ffr.wikipedia.org%3ASurdit%C3%A9+de+perception"></span></span></span>.</span> </li> </ol></div> </div> <ul id="bandeau-portail" class="bandeau-portail"><li><span class="bandeau-portail-element"><span class="bandeau-portail-icone"><span class="noviewer" typeof="mw:File"><a href="/wiki/Portail:M%C3%A9decine" title="Portail de la médecine"><img alt="icône décorative" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Star_of_life2.svg/24px-Star_of_life2.svg.png" decoding="async" width="24" height="24" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Star_of_life2.svg/36px-Star_of_life2.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Star_of_life2.svg/48px-Star_of_life2.svg.png 2x" data-file-width="192" data-file-height="192" /></a></span></span> <span class="bandeau-portail-texte"><a href="/wiki/Portail:M%C3%A9decine" title="Portail:Médecine">Portail de la médecine</a></span> </span></li> </ul>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1&useformat=desktop" alt="" width="1" height="1" style="border: none; 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