PDB50-ASBMB meeting

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class="container belowFold"> <div class="row"> <div class="col-md-6">   <img src="https://cdn.rcsb.org/rcsb-pdb/general_information/news_publications/newsletters/2021q3/images/speaker-collage.png" height="230px" alt="Collage of PDB50 meeting speakers" class=" popUp" style="display: block;"/> </div> <div class="col-md-6"> <p><img src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/PDB50-long.png" height="230px" alt="image: 50 Years of PDB"/></p> </div> </div> <div>  </div> <br>  <p>The inaugural PDB50 event was held virtually in May 2021. <a href="https://www.youtube.com/playlist?list=PLHib7JgKNUUcHwWspP7nikECO48f0cNj6">Click here</a> to watch the full symposium. To access individual presentations, click on the links below.</p> <section> <h3>Speakers</h3> <div class="col-12"> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Eddy Arnold" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/eddyArnold.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Eddy Arnold</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">Rutgers, The State University of New Jersey</li> <li class="profileSlab-infoItem talkTitle"><strong>Using HIV-1 reverse transcriptase structures to guide anti-AIDS drug discovery</strong> <br><span class="watch" url="rLsGNXFuCJU">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Helen M. Berman" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/helenBerman.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Helen M. Berman</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">Rutgers, The State University of New Jersey</li> <li class="profileSlab-infoItem">University of Southern California</li> <li class="profileSlab-infoItem talkTitle"><strong>The evolution of the Protein Data Bank as a community resource</strong> <br><span class="watch" url="IaUdB_F48pI">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Thomas L. Blundell" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/thomasBlundell.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Thomas L. Blundell</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">University of Cambridge</li> <li class="profileSlab-infoItem talkTitle"><strong>A personal history of five decades of structural biology and the PDB: From the X-ray structure of 2-Zinc <br/>insulin hexamer in 1970 to Cryo-EM structures of DNA-PK from DNA repair in 2020</strong> <br><span class="watch" url="qXVQ-dNkUpQ">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Alexandre M. J. J. Bonvin" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/alexandreBonvin.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Alexandre M. J. J. Bonvin</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">Utrecht University</li> <li class="profileSlab-infoItem talkTitle"><strong>Solving 3D puzzles by integrative modelling using PDB structures</strong> <br><span class="watch" url="_ymi9zmTL2w">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Stephen K. Burley" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/stephenBurley.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Stephen K. Burley</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">Rutgers, The State University of New Jersey</li> <li class="profileSlab-infoItem">University of California, San Diego</li> <li class="profileSlab-infoItem talkTitle"><strong>Impact of structural biologists and fifty years of Protein Data Bank operations on drug discovery and development</strong> <br><span class="watch" url="FJl4Dmq7Hcg">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Wah Chiu" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/wahChiu.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Wah Chiu</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">Stanford University</li> <li class="profileSlab-infoItem talkTitle"><strong>Cryo-EM of biomolecules at Ångström resolutions</strong> <br><span class="watch" url="MsKkt4EBM0U">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Johann Deisenhofer" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/johannDeisenhofer.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Johann Deisenhofer</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">University of Texas Southwestern Medical Center</li> <li class="profileSlab-infoItem talkTitle"><strong>50 years of PDB — from crazy idea to treasure</strong> <br><span class="watch" url="SfS0TlA2SVg">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Juli Feigon" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/juliFeigon.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Juli Feigon</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">University of California, Los Angeles</li> <li class="profileSlab-infoItem talkTitle"><strong>Structural biology of telomerase</strong> <br><span class="watch" url="70fAZmyATp0">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Angela M. Gronenborn" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/angelaGroneborn.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Angela M. Gronenborn</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">University of Pittsburgh</li> <li class="profileSlab-infoItem talkTitle"><strong>Integrated BioNMR — getting by with a little help from my friends</strong> <br><span class="watch" url="-F2Jc76BpzQ">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Jennifer L. Martin" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/jenniferMartin.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Jennifer L. Martin</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">University of Wollongong</li> <li class="profileSlab-infoItem talkTitle"><strong>Science, crystallography, reflections: A journey with the PDB over 35 years</strong> <br><span class="watch" url="CowwtsDv24Q">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Stephen L. Mayo" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/setphenMayo.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Stephen L. Mayo</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">California Institute of Technology</li> <li class="profileSlab-infoItem talkTitle"><strong>Antibody small molecule conjugates with computationally designed target binding synergy</strong> <br><span class="watch" url="ztjGBMFzTME">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Zihe Rao" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/ziheRao.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Zihe Rao</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">ShanghaiTech University</li> <li class="profileSlab-infoItem">Tsinghua University</li> <li class="profileSlab-infoItem talkTitle"><strong>Structural insight into SARS-CoV-2 replication and transcription complex (RTC)</strong> <br><span class="watch" url="vB76HVybr7w">Watch Presentation</span> </li> </ul> </div> </div> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Hao Wu" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/haoWu.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Hao Wu</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">Harvard Medical School</li> <li class="profileSlab-infoItem">Boston Children's Hospital</li> <li class="profileSlab-infoItem talkTitle"><strong>"Speck"tacular inflammasomes: structures of supramolecular complexes in innate immunity</strong> <br><span class="watch" url="DmtQ8GVuXSw">Watch Presentation</span> </li> </ul> </div> </div> </div> </section> <br/> <h3>Poster Presentations</h3> <p>~275 posters were presented during the meeting</p> <p>Abstracts: Tuesday May 4 <a href="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/day1-abstracts.pdf" >(PDF)</a> | Wednesday May 5 <a href="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/day2-abstracts.pdf">(PDF)</a></p> <p>wwPDB Posters: The Life and Times of the PDB Format - Looking Towards the Future with mmCIF <a href="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/LookingTowards.pdf" >(PDF)</a></p> <p>Trends in macromolecular structure data across 50 years of the PDB <a href="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/TrendsFiftyyears.pdf" >(PDF)</a></p> <br/> <h3>Poster Prizes</h3> <section> <h5>Best in High School: </h5> <div class="col-12"> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Nicholas Mamisashvili" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/NicholasMamisashvili.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Nicholas Mamisashvili</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">Shelter Island High School</li> <li class="profileSlab-infoItem talkTitle"><strong>Molecular Dynamics Simulation of 6PEY.pdb a Novel Mutation in the Enzyme Methylenetetrahydrofolate Reductase</strong></li> </ul> </div> </div> <h5>Best in Undergraduate: </h5> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Ijeoma Okoye" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/IjeomaOkoye.jpeg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Ijeoma Okoye</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">Vassar College</li> <li class="profileSlab-infoItem talkTitle"><strong>X-ray and Antioxidant Determination of Butein and 2’,4’-dihydroxy-3,4-dimethoxychalcone to <br/>Examine their Antimalarial Activity by Binding to Falcipain-2</strong></li> </ul> </div> </div> <h5>Best in Graduate: </h5> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Daniel Sultanov" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/DanielPic.png" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Daniel Sultanov</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">New York University</li> <li class="profileSlab-infoItem talkTitle"><strong>Mining for functional ribosomal variants in Saccharomyces cerevisiae</strong></li> </ul> </div> </div> <h5>Best in Postdoctoral Scholars: </h5> <div class="profileSlab"> <figure class="profileSlab-figure"><img alt="Seda Kocaman" class="profileSlab-img" src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/SedaKocaman.jpg" /></figure> <div class="profileSlab-body"> <h3 class="profileSlab-heading"><span class="profileSlab-headingLink">Seda Kocaman</span></h3> <ul class="profileSlab-infoList"> <li class="profileSlab-infoItem">National Institute of Environmental Health Sciences</li> <li class="profileSlab-infoItem talkTitle"><strong>Different ATP binding states of the essential AAA (ATPases Associated with various Activities)-ATPase<br/> Rix7 facilitate substrate translocation in ribosome biogenesis </strong></li> </ul> </div> </div> </div> </section> <br/> <h3>Acknowledgements</h3> <p>PDB50 was organized by members of the <a href="https://foundation.wwpdb.org/" target="_blank" rel="noopener">wwPDB Foundation</a>:</p> <ul> <li><b>Celia Schiffer</b>, University of Massachusetts Medical School</li> <li><b>Helen M. Berman</b>, Rutgers, The State University of New Jersey; RCSB PDB</li> <li><b>Stephen K. Burley</b>, Rutgers, The State University of New Jersey; RCSB PDB</li> <li><b>Jeffrey C. Hoch</b>, University of Connecticut; BMRB</li> <li><b>Gerard J. Kleywegt</b>, European Bioinformatics Institute; PDBe</li> <li><b>Genji Kurisu</b>, Osaka University; PDBj</li> <li><b>John L. Markley</b>, University of Wisconsin–Madison; BMRB</li> <li><b>Sameer Velankar</b>, European Bioinformatics Institute; PDBe</li> <li><b>Christine Zardecki</b>, Rutgers, The State University of New Jersey; RCSB PDB</li> </ul> <p>The organizers thank these sponsors for their generous support of PDB50:</p> <img src="https://cdn.rcsb.org/wwpdb/docs/pdb50yrs2021/Acknowledgements.png" > </div> <br> <div id="myModal" class="modal" > <div id="myModalContent" class="modal-content"> <div id="myModalHeader" class="modal-header"> <span id="myClose" class="close">×</span></div> <div id="myModalBody" class="modal-body"> </div> </div> </div> <footer class="footer"> <div class="container-fluid hidden-print" style="position: relative;"> <div class="row topFooter tinyPad"> <div class="ScreenLimitFooter"> <div class="col-sm-4"> <div class="smallMarginTop"> <a href="https://www.facebook.com/pages/Worldwide-PDB/223648640998643" target="_blank"><img src="https://cdn.rcsb.org/wwpdb/img/core/facebook.png" width="24" height="24"></a> <a href="https://www.youtube.com/channel/UCgM7zpapumhWHDMV11FIz0Q" target="_blank"><img src="https://cdn.rcsb.org/wwpdb/img/core/youtube-logo.png" width="24" height="24"></a> <a href="#"><img alt="RSS Feed for the Latest News" src="https://cdn.rcsb.org/wwpdb/img/core/rss.png" width="24" height="24"></a> <a href="mailto: info@wwpdb.org"><img src="https://cdn.rcsb.org/wwpdb/img/core/mail.png" width="24" height="24"></a> </div> <div class="smallMarginTop"> <a href="/news/news.php"> <p><a href="/news/news.php">News & Announcements</a></p> </a> </div> <div> <p><a href="https://lists.wwpdb.org/list/pdb-l.lists.wwpdb.org">Community Bulletin Board</a></p> </div> <div><a class='brand hidden-desktop' href='http://foundation.wwpdb.org/' target='_blank'><img src="https://cdn.rcsb.org/wwpdb/img/core/wwpdb-foundation-logo.png" class="logoLimit smallMarginTop"></a></div> </div> <div class="col-sm-4"> <div class="tinyMarginTop"> <h4><a class="h4-link" href="/download/downloads.php">Download Archive</a></h4> </div> <div class="smallMarginTop"> <a href="https://files.wwpdb.org/pub/pdb/">RCSB PDB</a> | <a href="https://ftp.ebi.ac.uk/pub/databases/pdb/">PDBe</a> | <a href="https://ftp.pdbj.org/pub/pdb/">PDBj</a> <br> <a href="/download/downloads.php">Instructions</a> </div> <div class="row"> <div class="col-sm-4"> <div class="tinyMarginTop"> <h4>Archive Snapshots</h4> </div> <div class="smallMarginTop"> <a href="https://s3snapshots.rcsb.org">RCSB PDB (https)</a> | <a href="ftp://snapshots.pdbj.org/">PDBj</a> </div> </div>  </div> </div> <div class="col-sm-3"> <h4> Cite wwPDB: </h4> <div class="smallMarginTop"> <em>Nature Structural Biology</em> <strong>10</strong>, 980 (2003)<br> <a href="http://dx.doi.org/10.1038/nsb1203-980" target="_blank">doi: 10.1038/nsb1203-980</a> <p class="tinyMarginTop"><a href="/about/publications.php">More publications</a></p> </div> </div> <div class="row" style="padding: 40px 0px 10px 10px"> <div class="col-sm-7"> <div class="tinyPad"> <h4>wwPDB Members:</h4> </div> <div class="col-sm-2 tinyPad"><a href="https://www.rcsb.org/" target="blank"><img src="https://cdn.rcsb.org/wwpdb/img/core/rcsb-pdb.png" class="logoLimit img-responsive"></a></div> <div class="col-sm-2 tinyPad"><a href="https://www.pdbj.org/" target="blank"><img src="https://cdn.rcsb.org/wwpdb/img/core/pdbj.png" class="logoLimit img-responsive"></a></div> <div class="col-sm-2 tinyPad"><a href="http://bmrb.io/" target="blank"><img src="https://cdn.rcsb.org/wwpdb/img/core/bmrb.png" class="logoLimit img-responsive"></a></div> <div class="col-sm-2 tinyPad"><a href="https://www.ebi.ac.uk/pdbe/emdb/" target="blank"><img src="https://cdn.rcsb.org/wwpdb/img/core/emdb.png" class="logoLimit img-responsive"></a></div> <div class="col-sm-2 tinyPad"><a href="https://www.ebi.ac.uk/pdbe/" target="blank"><img src="https://cdn.rcsb.org/wwpdb/img/core/pdbe.png" class="logoLimit img-responsive"></a></div> </div> <div class="col-sm-1"><br></br></div> <div class="col-sm-4"> <div class="row"> <div class="col-xs-6"> <a href='http://www.CoreTrustSeal.org' target='_blank'><img src="https://cdn.rcsb.org/wwpdb/img/homepage/CoreTrustSeal-logo-transparent-small.png" class='img-responsive seal' style="border-right: 1px solid #666; 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