CINXE.COM
New NIH funding awarded to the Department of Bioengineering and Therapeutic Sciences in 2011 · School of Pharmacy · UCSF
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2011</h1> </div> <!-- /#content-header --> <div id="content-area" class="clearfix"> <div class="region region-content"> <div id="block-system-main" class="block block-system"> <div class="content"> <div class="panel-display burr-flipped clearfix " id="news-page"> <div class="burr-flipped-container burr-flipped-content-container clearfix"> <div class="burr-flipped-content burr-flipped-content-region panel-panel"> <div class="burr-flipped-content-inner burr-flipped-content-region-inner panel-panel-inner"> <div class="panel-pane pane-views-panes pane-news-page-panel-pane-2" > <div class="pane-content"> <div class="view view-news-page view-id-news_page view-display-id-panel_pane_2 view-dom-id-9573fb9c2febbe10218de6405153b5a1"> <div class="view-content"> <div class="submitted"> <div> <div class="views-field-created views-field">By David Jacobson / Fri Apr 13, 2012</div> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-node-content" > <div class="pane-content"> <div id="node-2381" class="node node-openacademy-news node-promoted clearfix" about="/news/2012/04/new-nih-funding-awarded-department-bioengineering-therapeutic-sciences-2011" typeof="sioc:Item foaf:Document"> <span property="dc:title" content="" class="rdf-meta element-hidden"></span> <div class="content"> <div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>New research support awarded to the <abbr title="University of California, San Francisco">UCSF</abbr> School of Pharmacy by the National Institutes of Health during the 2011 fiscal year included a half-dozen on-going projects by <abbr title="Department of Bioengineering and Therapeutic Sciences">BTS</abbr> faculty:</p> <h2>Genetic mutations and liver cancer</h2> <h3>Xin Chen, <abbr title="Doctor of Philosophy">PhD</abbr></h3> <ul> <li>Associate adjunct professor</li> <li>Awarded two new grants totaling $351,488 from the National Institute of Alcohol Abuse and Alcoholism (part of a two-year $405,563 grant) and the <strong>National Cancer Institute</strong> (part of a two-year $369,642 grant)</li> </ul> <p></p><div class="media media-element-container media-third ucsf-images-wrapping-right"><picture class="media-element file-third"> <!--[if IE 9]><video style="display: none;"><![endif]--> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/20140716_1_0051.jpg?itok=5TGvkJUh&timestamp=1557782025 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/20140716_1_0051.jpg?itok=yYRdPU2L&timestamp=1557782025 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/20140716_1_0051.jpg?itok=OVWiR9Hx&timestamp=1557782025 3x" media="(min-width: 1025px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/20140716_1_0051.jpg?itok=0kRvA_cR&timestamp=1557782025 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/20140716_1_0051.jpg?itok=yYRdPU2L&timestamp=1557782025 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_1_5x/public/20140716_1_0051.jpg?itok=1nfQJp5l&timestamp=1557782025 3x" media="(min-width: 656px) and (max-width: 1024px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_quarter/public/20140716_1_0051.jpg?itok=tCtgBytm&timestamp=1557782025 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/20140716_1_0051.jpg?itok=0kRvA_cR&timestamp=1557782025 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/20140716_1_0051.jpg?itok=yYRdPU2L&timestamp=1557782025 3x" media="(min-width: 481px) and (max-width: 655px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/20140716_1_0051.jpg?itok=0kRvA_cR&timestamp=1557782025 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/20140716_1_0051.jpg?itok=yYRdPU2L&timestamp=1557782025 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_1_5x/public/20140716_1_0051.jpg?itok=1nfQJp5l&timestamp=1557782025 3x" media="(min-width: 431px) and (max-width: 480px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/20140716_1_0051.jpg?itok=5TGvkJUh&timestamp=1557782025 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/20140716_1_0051.jpg?itok=yYRdPU2L&timestamp=1557782025 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/20140716_1_0051.jpg?itok=OVWiR9Hx&timestamp=1557782025 3x" media="(min-width: 0px) and (max-width: 430px)"></source> <!--[if IE 9]></video><![endif]--> <img class="media-element file-third" src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/20140716_1_0051.jpg?itok=5TGvkJUh&timestamp=1557782025" alt="Chen" title="" /> </picture> <div class="field field-name-field-image-credit-term field-type-taxonomy-term-reference field-label-hidden"> <div class="field-items"> <div class="field-item even"><a href="https://elisabeth-fall.squarespace.com/" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Elisabeth Fall</a></div> </div> </div> <div class="field field-name-field-image-caption field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Xin Chen, PhD</p></div></div></div></div> <p>In the first of the two new studies, Chen focuses on how alcohol contributes to liver cancer development. Increased alcohol consumption leads to liver diseases and eventually liver cancer. In this study, Chen is investigating genetic mutations that contribute to alcohol-induced liver cancer development in mice.</p> <p>In the second new study, Chen is focusing just on hepatitis B (<abbr title="hepatitis B virus">HBV</abbr>) and hepatitis C (<abbr title="hepatitis C virus">HBV</abbr>) infections, the major risk factors for liver cancer. While it is known that <abbr title="hepatitis B virus">HBV</abbr> and <abbr title="hepatitis C virus">HBV</abbr> play direct roles, the resulting cancer takes a long time to develop and often does not occur at all. She seeks to determine what additional or on-going genetic mutations are occurring in the virally damaged liver cells.</p> <p>Chen aims to precisely determine which changes to key liver cell genes lead to cancer, providing the basis for better ways to prevent and treat the disease.</p> <h2>New devices to treat retinal diseases</h2> <h3>Tejal Desai, <abbr title="Doctor of Philosophy">PhD</abbr></h3> <ul> <li>Professor and vice chair for education</li> <li>Awarded $379,264 from the National Eye Institute as part of a four-year $1.5 million research grant</li> </ul> <p></p><div class="media media-element-container media-media-full ucsf-images-wrapping-right" style="max-width: 250px;"><picture class="media-element file-media-full"> <!--[if IE 9]><video style="display: none;"><![endif]--> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/0413_desai_0.jpg?itok=bnHVq7LP&timestamp=1567625156 1x" media="(min-width: 1025px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/0413_desai_0.jpg?itok=z7AOZ5Vz&timestamp=1567625156 1x" media="(min-width: 656px) and (max-width: 1024px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/0413_desai_0.jpg?itok=fBmJv4JZ&timestamp=1567625156 1x" media="(min-width: 481px) and (max-width: 655px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/0413_desai_0.jpg?itok=fBmJv4JZ&timestamp=1567625156 1x" media="(min-width: 431px) and (max-width: 480px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/0413_desai_0.jpg?itok=UeQskEHL&timestamp=1567625156 1x" media="(min-width: 0px) and (max-width: 430px)"></source> <!--[if IE 9]></video><![endif]--> <img class="media-element file-media-full" src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/0413_desai_0.jpg?itok=bnHVq7LP&timestamp=1567625156" alt="Desai" title="" /> </picture> <div class="field field-name-field-image-credit-term field-type-taxonomy-term-reference field-label-hidden"> <div class="field-items"> <div class="field-item even"><a href="https://www.majedphoto.com/" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">© majedphoto.com</a></div> </div> </div> <div class="field field-name-field-image-caption field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Tejal Desai, PhD</p></div></div></div></div> <p>Desai is developing a nanoporous thin-film device that can be used to treat eye disease. It will be as thin as a strand of hair with pores about 25 nanometers in diameter. Once deployed into the back of the eye, the device will deliver sustained doses of medications that can effectively fight the wet form of macular degeneration, a disease that damages sharp, central vision.</p> <p>The new drug diffusion device would have multiple advantages over current treatments, which call for monthly injections of drugs into the eyeball with large-bore needles. Beyond the daunting discomfort, the injection method is neither pharmacologically optimal nor cost efficient due to the drugs’ rapid breakdown and clearance from the body.</p> <p>By contrast, the new device would protect the drugs from degradation and deliver a sustained dose over several months. This study will develop and test prototypes in in vitro and animal eye models.</p> <p>Desai’s research seeks to create new and improved tools for treating retinal diseases.</p> <h2>Biosensors that detect and respond to small molecules inside cells</h2> <h3>Tanja Kortemme, <abbr title="Doctor of Philosophy">PhD</abbr></h3> <ul> <li>Associate professor</li> <li>Awarded $231,750 from the National Institute of Biomedical Imaging and Bioengineering as part of a two-year $424,875 research grant</li> </ul> <p></p><div class="media media-element-container media-media-full ucsf-images-wrapping-right" style="max-width: 188px;"><picture class="media-element file-media-full"> <!--[if IE 9]><video style="display: none;"><![endif]--> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/0413_kortemme_0.jpg?itok=Ymz049UP&timestamp=1567625174 1x" media="(min-width: 1025px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/0413_kortemme_0.jpg?itok=hvqepuFl&timestamp=1567625174 1x" media="(min-width: 656px) and (max-width: 1024px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/0413_kortemme_0.jpg?itok=7yfAzObH&timestamp=1567625174 1x" media="(min-width: 481px) and (max-width: 655px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/0413_kortemme_0.jpg?itok=7yfAzObH&timestamp=1567625174 1x" media="(min-width: 431px) and (max-width: 480px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/0413_kortemme_0.jpg?itok=cQpLJ4QW&timestamp=1567625174 1x" media="(min-width: 0px) and (max-width: 430px)"></source> <!--[if IE 9]></video><![endif]--> <img class="media-element file-media-full" src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/0413_kortemme_0.jpg?itok=Ymz049UP&timestamp=1567625174" alt="Kortemme" title="" /> </picture> <div class="field field-name-field-image-credit-term field-type-taxonomy-term-reference field-label-hidden"> <div class="field-items"> <div class="field-item even"><a href="https://www.majedphoto.com/" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">© majedphoto.com</a></div> </div> </div> <div class="field field-name-field-image-caption field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Tanja Kortemme, PhD</p></div></div></div></div> <p>Kortemme seeks to create a new type of modular sensor made from biological materials; in this case, protein molecules inside cells. Such sensors would allow real-time detection of small molecules such as intracellular signals, metabolites, and drugs inside living cells and organisms.</p> <p>The biosensors will be made by reengineering heterodimeric proteins, which are pairs of proteins that normally interact to fulfill their biological roles. For the sensors, they will be altered so that they can only come together when a particular small molecule is present. This will be done by transplanting binding sites for the small molecules into the protein-protein interface.</p> <p>The reengineered proteins will also each be linked to half of a so-called reporter, such as green fluorescent protein, that has been split in two. The reporter will only glow when the reengineered proteins combine, thus signaling the presence of the small molecules.</p> <p>That split reporter can also be an enzyme, which is a protein molecule that affects the rates of chemical reactions and thus controls biological processes. In that case, when the heterodimeric proteins combine in the presence of the small molecules, the enzyme will be rejoined and activated.</p> <p>Thus, Kortemme’s biosensors may go beyond detecting small molecules. If the reporter proteins she uses are enzymes, the biosensors could also control biological processes, such as activating cellular events that make more of the target molecules or metabolize them if, for example, they are toxic.</p> <p>Kortemme is making new tools to detect and respond to many molecular targets. The biosensors could be used for probing cellular processes or for new medical diagnostics and treatments.</p> <h2>Inducing antibodies to neutralize <abbr title="human immunodeficiency virus">HIV</abbr></h2> <h3>Francis Szoka, <abbr title="Doctor of Philosophy">PhD</abbr></h3> <ul> <li>Professor</li> <li>Awarded $193,125 from the National Institute of Allergy and Infectious Diseases as part of a two-year $424,875 research grant</li> </ul> <p></p><div class="media media-element-container media-media-full ucsf-images-wrapping-right" style="max-width: 250px;"><picture class="media-element file-media-full"> <!--[if IE 9]><video style="display: none;"><![endif]--> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/0413_szoka_0.jpg?itok=iqLnkqGj&timestamp=1567625195 1x" media="(min-width: 1025px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/0413_szoka_0.jpg?itok=zCDEByef&timestamp=1567625195 1x" media="(min-width: 656px) and (max-width: 1024px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/0413_szoka_0.jpg?itok=uIvTrUXY&timestamp=1567625195 1x" media="(min-width: 481px) and (max-width: 655px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/0413_szoka_0.jpg?itok=uIvTrUXY&timestamp=1567625195 1x" media="(min-width: 431px) and (max-width: 480px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/0413_szoka_0.jpg?itok=x-gjQOnu&timestamp=1567625195 1x" media="(min-width: 0px) and (max-width: 430px)"></source> <!--[if IE 9]></video><![endif]--> <img class="media-element file-media-full" src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/0413_szoka_0.jpg?itok=iqLnkqGj&timestamp=1567625195" alt="Szoka" title="" /> </picture> <div class="field field-name-field-image-credit-term field-type-taxonomy-term-reference field-label-hidden"> <div class="field-items"> <div class="field-item even"><a href="https://www.majedphoto.com/" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">© majedphoto.com</a></div> </div> </div> <div class="field field-name-field-image-caption field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Francis Szoka, PhD</p></div></div></div></div> <p>Szoka is making molecules known as immunogens designed to stimulate a virus-neutralizing immune system response against a region of an <abbr title="human immunodeficiency virus">HIV</abbr> protein called GP41.</p> <p>GP41 is part of a protein complex embedded in and protruding from <abbr title="human immunodeficiency virus">HIV</abbr>’s viral envelope. The complex allows the virus to attach to and enter T-cells via a surface receptor called CD4.</p> <p>The region of GP41 that Szoka is focusing on is the target of ongoing <abbr title="human immunodeficiency virus">HIV</abbr> vaccine development aimed at triggering the response of antibodies that would neutralize the virus before it enters cells.</p> <p>Szoka’s unique approach is to stimulate that immune response with immunogens (linked amino acids called peptides) that mimic the targeted GP41 region but include specific chemical alterations (post-translational modifications) that may occur in that part of the protein during <abbr title="human immunodeficiency virus">HIV</abbr> infection.</p> <p>Szoka hypothesizes that it is those modifications that induce the neutralizing antibodies to recognize the GP41 region.</p> <p>His lab has synthesized chemically modified peptides that mimic the protein region and incorporated the immunogens into lipid nanocapsules. He thinks this will maximize the immune response and generate neutralizing antibodies to <abbr title="human immunodeficiency virus">HIV</abbr>.</p> <p>Szoka will ultimately use the most effective immunogens in a vaccine meant to induce <abbr title="human immunodeficiency virus">HIV</abbr>-neutralizing antibodies, which could be a precursor to a vaccine to prevent <abbr title="acquired immune deficiency syndrome">AIDS</abbr>.</p> <h2>Modeling and probing the cell cycle</h2> <h3>Chao Tang, <abbr title="Doctor of Philosophy">PhD</abbr></h3> <ul> <li>Adjunct professor</li> <li>Awarded $410,793 from the National Institute of General Medical Sciences, part of a four-year $1.6 million research grant</li> </ul> <p></p><div class="media media-element-container media-media-full ucsf-images-wrapping-right" style="max-width: 188px;"><picture class="media-element file-media-full"> <!--[if IE 9]><video style="display: none;"><![endif]--> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/0413_tang_0.jpg?itok=cmZAvRDo&timestamp=1567625213 1x" media="(min-width: 1025px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/0413_tang_0.jpg?itok=QXUVphRp&timestamp=1567625213 1x" media="(min-width: 656px) and (max-width: 1024px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/0413_tang_0.jpg?itok=PtJ6UkLi&timestamp=1567625213 1x" media="(min-width: 481px) and (max-width: 655px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/0413_tang_0.jpg?itok=PtJ6UkLi&timestamp=1567625213 1x" media="(min-width: 431px) and (max-width: 480px)"></source> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/0413_tang_0.jpg?itok=INPx2Z3x&timestamp=1567625213 1x" media="(min-width: 0px) and (max-width: 430px)"></source> <!--[if IE 9]></video><![endif]--> <img class="media-element file-media-full" src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/0413_tang_0.jpg?itok=cmZAvRDo&timestamp=1567625213" alt="Tang" title="" /> </picture> <div class="field field-name-field-image-credit-term field-type-taxonomy-term-reference field-label-hidden"> <div class="field-items"> <div class="field-item even"><a href="https://www.majedphoto.com/" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">© majedphoto.com</a></div> </div> </div> <div class="field field-name-field-image-caption field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Chao Tang, PhD</p></div></div></div></div> <p>Tang is developing mathematical models of how cell division and replication (cell cycle) are regulated. The cell cycle is one of the most fundamental and complex biological processes, and one that goes awry in cancer’s cellular proliferation.</p> <p>In this project, Tang is building and validating computer models of the entire cell cycle system in yeast, which share similar cell cycle processes and proteins with human cells. He is focusing on key checkpoints and switches that ensure the process, including the accurate and complete replication of <abbr title="deoxyribonucleic acid">DNA</abbr>, is occurring correctly.</p> <p>Tang plans to use his computer models to identify the effects of different disturbances on the entire cell cycle regulation system and at key checkpoints. He will use experiments in actual yeast cells to test his mathematical model’s predictions.</p> <p>Tang expects that simulating disturbances of the cell division process will help explain why certain gene mutations can lead to cancer and may suggest new treatments.</p></div></div></div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-news-page-panel-pane-3" > <h2 class="pane-title">Tags</h2> <div class="pane-content"> <div class="view view-news-page view-id-news_page view-display-id-panel_pane_3 view-dom-id-058ef8cb1ff19926ffe1f39a1be37d1b"> <div class="view-content"> <div> <div class="views-field views-field-field-keywords-revision-id"> <span class="views-label views-label-field-keywords-revision-id">Topics: </span> <div class="field-content"><a href="/topics-expertise/alcohol" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">alcohol</a>, <a href="/topics-expertise/liver-cancer" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">liver cancer</a>, <a href="/topics-expertise/hepatitis-b" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">hepatitis B</a>, <a href="/topics-expertise/hepatitis-c" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">hepatitis C</a>, <a href="/topics-expertise/nanotechnology" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">nanotechnology</a>, <a href="/topics-expertise/eye-disease" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">eye disease</a>, <a href="/topics-expertise/retinal-diseases" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">retinal diseases</a>, <a href="/topics-expertise/biosensors" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">biosensors</a>, <a href="/topics-expertise/immunogens" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">immunogens</a>, <a href="/topics-expertise/vaccine" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">vaccine</a>, <a href="/topics-expertise/hiv-neutralizing-antibodies" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">HIV-neutralizing antibodies</a>, <a href="/topics-expertise/aids-acquired-immunodeficiency-syndrome" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">AIDS (Acquired Immunodeficiency Syndrome)</a>, <a href="/topics-expertise/cell-cycle" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">cell cycle</a>, <a href="/topics-expertise/cell-division" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">cell division</a>, <a href="/topics-expertise/national-institutes-health-nih" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">National Institutes of Health (NIH)</a></div> </div> <div class="views-field views-field-field-categories-revision-id"> <span class="views-label views-label-field-categories-revision-id">Category: </span> <div class="field-content"><a href="/categories/research" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Research</a></div> </div> <div class="views-field views-field-nothing"> <span class="views-label views-label-nothing">Sites: </span> <div class="field-content">School of Pharmacy, Department of Bioengineering and Therapeutic Sciences, PharmD Degree Program, BMI, QBC, CCB, PSPG, Bioinformatics, Biophysics</div> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-related-profiles-news-related-profiles-pane" > <h2 class="pane-title">Related profiles</h2> <div class="pane-content"> <div class="view view-related-profiles view-id-related_profiles view-display-id-news_related_profiles_pane columns-4 view-dom-id-e9daaf208a9c3478c3eb63800ec360af"> <div class="view-content"> <div class="relatedprofile"> <span class="views-field 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class="relatedprofile"> <span class="views-field views-field-field-person-headshot-photo"> <span class="field-content"><a href="https://pharmacy.ucsf.edu/francis-szoka"><picture > <!--[if IE 9]><video style="display: none;"><![endif]--> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/szoka-profile_0.jpg?itok=8EWw1_7I&timestamp=1652111801 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_third/public/person/photo/szoka-profile_0.jpg?itok=Yz-FMttJ&timestamp=1652111801 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/szoka-profile_0.jpg?itok=gaB57rPC&timestamp=1652111801 3x" media="(min-width: 1025px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/szoka-profile_0.jpg?itok=8EWw1_7I&timestamp=1652111801 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/person/photo/szoka-profile_0.jpg?itok=vm7agxcd&timestamp=1652111801 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/szoka-profile_0.jpg?itok=gaB57rPC&timestamp=1652111801 3x" media="(min-width: 656px) and (max-width: 1024px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/szoka-profile_0.jpg?itok=8EWw1_7I&timestamp=1652111801 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/person/photo/szoka-profile_0.jpg?itok=vm7agxcd&timestamp=1652111801 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/szoka-profile_0.jpg?itok=gaB57rPC&timestamp=1652111801 3x" media="(min-width: 481px) and (max-width: 655px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/szoka-profile_0.jpg?itok=8EWw1_7I&timestamp=1652111801 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/person/photo/szoka-profile_0.jpg?itok=vm7agxcd&timestamp=1652111801 2x, 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href="https://pharmacy.ucsf.edu/francis-szoka">Francis Szoka</a></span> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-fieldable-panels-pane pane-current-171 pane-bundle-text" > <div class="pane-content"> <div class="fieldable-panels-pane"> <div class="field field-name-field-basic-text-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><hr /><p class="fine-print"><strong>About the School</strong>: The UCSF School of Pharmacy aims to solve the most pressing health care problems and strives to ensure that each patient receives the safest, most effective treatments. Our discoveries seed the development of novel therapies, and our researchers consistently lead the nation in NIH funding. The School’s doctor of pharmacy (PharmD) degree program, with its unique emphasis on scientific thinking, prepares students to be critical thinkers and leaders in their field.</p></div></div></div></div> </div> </div> </div> </div> <div class="burr-flipped-sidebar burr-flipped-content-region panel-panel"> <div class="burr-flipped-sidebar-inner burr-flipped-content-region-inner panel-panel-inner"> <div class="region region-sidebar region-background-callout"><div class="panel-pane pane-block pane-apachesolr-search-mlt-002 pane-basic" > <h2 class="pane-title">Related news</h2> <div class="pane-content"> <div class="item-list"><ul><li class="first"><a href="/news/2016/03/ucsf-school-pharmacy-leads-nih-funding-36th-year-row">UCSF School of Pharmacy leads in NIH funding for 36th year in a row</a></li> <li><a href="/news/2018/07/creating-tools-build-human-cell-atlas">Creating the tools to build a Human Cell Atlas</a></li> <li><a href="/news/2011/11/drugs-screened-effects-key-transporters-risk-dangerous-interactions">Drugs screened for effects on key transporters, risk of dangerous interactions</a></li> <li><a href="/news/2020/11/jamming-gears-deadly-virus">Jamming the gears of a deadly virus</a></li> <li class="last"><a href="/news/2010/12/reflection-30-years-top-nih-funding-ucsf-school-pharmacy">Reflection: 30 years of top NIH funding for UCSF School of Pharmacy</a></li> </ul></div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-openacademy-news-news-listing" > <h2 class="pane-title">Recent news</h2> <div class="pane-content"> <div class="view view-openacademy-news view-id-openacademy_news view-display-id-news_listing view-dom-id-8899b40829c0bf89dee754ed9ce0193f"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first clearfix"> <div class="views-field views-field-rendered"> <span class="field-content"><a href="/news/2024/11/jonathan-watanabe-named-chair-clinical-pharmacy"><picture > <!--[if IE 9]><video style="display: none;"><![endif]--> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=gMSuW5PV&timestamp=1732234689 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=cS5DKsaA&timestamp=1732234689 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=RUEN84HX&timestamp=1732234689 3x" media="(min-width: 1025px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=gMSuW5PV&timestamp=1732234689 1x, 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srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=gMSuW5PV&timestamp=1732234689 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=cS5DKsaA&timestamp=1732234689 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=RUEN84HX&timestamp=1732234689 3x" media="(min-width: 431px) and (max-width: 480px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=gMSuW5PV&timestamp=1732234689 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=cS5DKsaA&timestamp=1732234689 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=RUEN84HX&timestamp=1732234689 3x" media="(min-width: 0px) and (max-width: 430px)" /> <!--[if IE 9]></video><![endif]--> <img src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/jonathan_watanabe_headshot_2018_balboapark_cropped_0.jpg?itok=gMSuW5PV&timestamp=1732234689" alt="Jonathan Watanabe" title="" /> </picture></a></span> </div> <div class="views-field views-field-title"> <span class="field-content"><a href="/news/2024/11/jonathan-watanabe-named-chair-clinical-pharmacy">Jonathan Watanabe Named Chair of Clinical Pharmacy</a></span> </div> <div class="views-field views-field-created"> <span class="field-content">Fri Nov 22, 2024</span> </div> </div> <div class="views-row views-row-2 views-row-even clearfix"> <div class="views-field views-field-rendered"> <span class="field-content"><a href="/news/2024/11/alumni-spotlight-constant-change-bench-veterinary-pharmacy"><picture > <!--[if IE 9]><video style="display: none;"><![endif]--> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=yp5Bd5nW&timestamp=1732320567 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=8HBSiOpq&timestamp=1732320567 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=2GUfzdMu&timestamp=1732320567 3x" media="(min-width: 1025px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=yp5Bd5nW&timestamp=1732320567 1x, 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srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=yp5Bd5nW&timestamp=1732320567 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=8HBSiOpq&timestamp=1732320567 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=2GUfzdMu&timestamp=1732320567 3x" media="(min-width: 431px) and (max-width: 480px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=yp5Bd5nW&timestamp=1732320567 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=8HBSiOpq&timestamp=1732320567 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=2GUfzdMu&timestamp=1732320567 3x" media="(min-width: 0px) and (max-width: 430px)" /> <!--[if IE 9]></video><![endif]--> <img src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/20241024_ucd_svm_pharmacy_team-11_2500px_wide.jpg?itok=yp5Bd5nW&timestamp=1732320567" alt="Contreras." title="" /> </picture></a></span> </div> <div class="views-field views-field-title"> <span class="field-content"><a href="/news/2024/11/alumni-spotlight-constant-change-bench-veterinary-pharmacy">Alumni Spotlight: Constant Change from Bench to Veterinary Pharmacy</a></span> </div> <div class="views-field views-field-created"> <span class="field-content">Fri Nov 22, 2024</span> </div> </div> <div class="views-row views-row-3 views-row-odd views-row-last clearfix"> <div class="views-field views-field-rendered"> <span class="field-content"><a href="/news/2024/11/oni-orisan-tamraz-awarded-stripe-double-helix-award-contributions-pharmacogenomics"><picture > <!--[if IE 9]><video style="display: none;"><![endif]--> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/oni-orisan_and_tamraz.jpg?itok=p2CJEN0c&timestamp=1731708601 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/oni-orisan_and_tamraz.jpg?itok=k971xPLk&timestamp=1731708601 3x" media="(min-width: 1025px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/oni-orisan_and_tamraz.jpg?itok=p2CJEN0c&timestamp=1731708601 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/oni-orisan_and_tamraz.jpg?itok=k971xPLk&timestamp=1731708601 3x" media="(min-width: 656px) and (max-width: 1024px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/oni-orisan_and_tamraz.jpg?itok=p2CJEN0c&timestamp=1731708601 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/oni-orisan_and_tamraz.jpg?itok=k971xPLk&timestamp=1731708601 3x" media="(min-width: 481px) and (max-width: 655px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/oni-orisan_and_tamraz.jpg?itok=p2CJEN0c&timestamp=1731708601 2x, 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class="field-content"><a href="/news/2024/11/oni-orisan-tamraz-awarded-stripe-double-helix-award-contributions-pharmacogenomics">Oni-Orisan and Tamraz Awarded STRIPE Double Helix Award for Contributions to Pharmacogenomics</a></span> </div> <div class="views-field views-field-created"> <span class="field-content">Fri Nov 15, 2024</span> </div> </div> </div> <div class="view-footer"> <div class="more-link"><a href="/news">SEE ALL ></a></div> </div> </div> </div> </div> </div> </div> </div> </div> </div><!-- /.burr-flipped --> </div> </div> </div> </div> <!-- content-area --> </div> <!-- content-header --> </div> <!-- /content-inner /content --> </div> <!-- /main --> </div> <!-- /page --> <div role="complementary" class="footer-make-a-gift-and-quote"> <div class="footer-make-a-gift"> <a href="https://makeagift.ucsf.edu/site/SPageServer?pagename=A1_API_GeneralGivingForm&Primary=Pharmacy">Make a gift</a> </div> <div class="footer-quote"> Science is the foun­da­tion of the School of 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