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data-hs-cos-general-type="widget" data-hs-cos-type="module"><span id="hs_cos_wrapper_widget_1721068949842_" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_text" style="" data-hs-cos-general-type="widget" data-hs-cos-type="text">CASE STUDY</span></div> </div> </div> </div> <div class="row-fluid-wrapper row-depth-1 row-number-5 cell_16546283222883-row-1-padding dnd-row"> <div class="row-fluid "> <div class="span12 widget-span widget-type-module dnd-module" style="" data-widget-type="module" data-x="0" data-w="12"> <div id="hs_cos_wrapper_dnd-modulemodule_15785536948801571" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module widget-type-rich_text widget-type-rich_text widget-type-rich_text" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"><span id="hs_cos_wrapper_dnd-modulemodule_15785536948801571_" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_rich_text" style="" data-hs-cos-general-type="widget" data-hs-cos-type="rich_text"><h2>Combinatorial Trimer-Controlled Synthesis of Antibody Libraries Enables Controlled Distribution of Amino Acids at Mutated Sites</h2></span></div> </div> </div> </div> <div class="row-fluid-wrapper row-depth-1 row-number-6 dnd-row cell_16546283222883-row-2-padding"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module" style="" data-widget-type="custom_widget" data-x="0" data-w="12"> <div id="hs_cos_wrapper_widget_1654628211907" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"><div class="content-lite relative "> <p>Despite the effectiveness of current methods for combinatorial library generation such as partially randomized (NNK) or completely randomized (NNN), there are unwanted codons which can be introduced that impact downstream antibody synthesis. This case study demonstrates the effectiveness of a trimer (Trinucleotide)-controlled approach for creating a combinatorial library for downstream <em>in vitro</em> antibody generation.</p> </div> </div> </div> </div> </div> <div class="row-fluid-wrapper row-depth-1 row-number-7 dnd-row"> <div class="row-fluid "> <div class="span12 widget-span widget-type-custom_widget dnd-module dnd-modulemodule_15785536722931530-flexbox-positioning" style="" data-widget-type="custom_widget" data-x="0" data-w="12"> <div id="hs_cos_wrapper_dnd-modulemodule_15785536722931530" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_module widget-type-linked_image widget-type-linked_image widget-type-linked_image" style="" data-hs-cos-general-type="widget" data-hs-cos-type="module"> <span id="hs_cos_wrapper_dnd-modulemodule_15785536722931530_" class="hs_cos_wrapper hs_cos_wrapper_widget hs_cos_wrapper_type_linked_image" style="" data-hs-cos-general-type="widget" 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