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t=this.menu.querySelectorAll("a.yle-header-search-suggestion")[e];t.classList.add(a.Selectors.autocomplete.selected),t.setAttribute("aria-selected","true"),this.input.setAttribute("aria-activedescendant",t.id)}},{key:"show",value:function(){this.menu.style.display="flex",this.container&&this.container.setAttribute("aria-expanded","true")}},{key:"hide",value:function(){this.menu.style.display="none",this.container&&this.container.setAttribute("aria-expanded","false")}},{key:"isShown",value:function(){return"flex"===this.menu.style.display}}]),t}()},{1:1,10:10,2:2,4:4,6:6}],4:[function(e,t,n){"use strict";Object.defineProperty(n,"__esModule",{value:!0}),n.Selectors=n.config=void 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function(e,t,n){t&&u(e.prototype,t),n&&u(e,n)}(e,[{key:"init",value:function(e,t){var n=0<arguments.length&&void 0!==e?e:"fi",r=1<arguments.length?t:void 0;this.searchForm=document.querySelector(i.Selectors.search.form),this.input=document.querySelector(i.Selectors.autocomplete.input),this.searchSubmit=document.querySelector(i.Selectors.search.submit),this.addSearchSubmitListeners(),void 0===r?this.autocomplete(function(e){var t=new a.Autocomplete(e);return{setCursorObserver:function(e){return t.setCursorObserver(e)},eventListeners:{keyup:function(e){return t.onInputChange(e)},keydown:function(e){return t.onKeyEvent(e)},focus:function(e){return t.onFocus(e)},blur:function(e){return t.onBlur(e)}}}}(n)):"off"!==r&&this.autocomplete(r)}},{key:"addSearchSubmitListeners",value:function(){var t=this;this.searchSubmit.addEventListener("mousedown",function(e){t.input.value||(e.preventDefault(),t.input.focus())}),this.searchSubmit.addEventListener("touchend",function(){""!==t.input.value&&t.searchForm.submit()}),this.searchForm.addEventListener("submit",function(e){t.input.value||e.preventDefault()})}},{key:"autocomplete",value:function(e){this.searchContainer=document.querySelector(i.Selectors.search.container),this.addSearchInputFocusListeners(),this.addInputEventListeners(e.eventListeners),this.addCloseSearchListeners(e.resultsContainerSelector)}},{key:"addInputEventListeners",value:function(t){var n=this;Object.keys(t).forEach(function(e){n.input.addEventListener(e,t[e])})}},{key:"changeInput",value:function(e){this.input.value=e}},{key:"addSearchInputFocusListeners",value:function(){this.input.addEventListener("focus",o.closeMegamenu),this.input.addEventListener("focus",function(){return(0,r.sendAnalyticsEvent)("header-searchfield-click")})}},{key:"addCloseSearchListeners",value:function(t){var n=this;document.querySelector("body").addEventListener("keyup",function(e){(0,s.isKey)(e,s.Keys.Escape)&&n.closeSearch()}),window.addEventListener("touchstart",function(e){!function(e,t,n){var r=l(e,t);if(n)return l(e,document.querySelector(n))&&r;return r}(e,n.searchContainer,t)||n.closeSearch()})}},{key:"closeSearch",value:function(){this.input.value="",this.input.blur()}}]),e}();function l(e,t){return!t.contains(e.target)}n.Search=c},{2:2,3:3,4:4,6:6,7:7}],9:[function(e,t,n){"use strict";Object.defineProperty(n,"__esModule",{value:!0}),n.initializeTunnus=function(e){return function(e){document.querySelector(".yle-header-tunnus-login").addEventListener("click",s(e.logIn,"header-tunnus-login-click")),document.querySelector(".yle-header-tunnus-menu-select-logout").addEventListener("click",s(e.logOut,"header-tunnus-logout-click")),document.querySelector(".yle-header-tunnus-menu-open").addEventListener("click",u),document.querySelector("body").addEventListener("click",o)}(e),function(e){e.state.subscribe(function(e){e.loggedIn?function(e){(function(e){var t=document.querySelector(".yle-header-action-open-tunnus-menu .initials");t.innerHTML=e;var n="".concat(e," 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dYurVp"></div></div><div class="GridSystem__GridRow-sc-15162af-1 ArticlePage__ArticleRow-sc-1sk1ppm-2 xJCCA"><div class="ArticlePage__ArticlePageMainColumn-sc-1sk1ppm-0 hwVvD"><div class="GridSystem__GridCell-sc-15162af-0 ArticlePage__ArticleGridCell-sc-1sk1ppm-1 glQKzU auYeu"><article class="sc-crHmcD juSxAh yle__article" itemtype="http://schema.org/Article" itemscope=""><div class="yle__article__header"><div class="sc-igXgud jmYlCu"><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-212923" class="sc-JkixQ bWSwDr">tiede</a></div><h1 class="sc-hGPBjI kUZNJC yle__article__heading yle__article__heading--1" itemprop="headline">Uusi melanoomalääke pidentää syöpäsairaan elinaikaa</h1><p class="sc-egiyK sc-gHjyzD ektcFN fmwojC yle__article__paragraph">Uudentyyppiset immunologiset syöpälääkkeet aktivoivat elimistön omat valkosolut hyökkäämään syöpäsoluja vastaan. Menetelmästä etsitään parannuskeinoa myös muiden syöpien hoitoon.</p><figure class="sc-llYSUQ ehrLkk yle__article__figure" itemprop="image" itemscope="" itemtype="http://schema.org/Photograph"><div itemprop="image" class="sc-iJKOTD ktKulI"><button class="sc-bYoBSM dKEKqe"><img alt="Kuvassa erilaisia luomien muutoksia." src="https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/w_1200,h_675,ar_1.7777777910232544,dpr_1,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/13-3-7449358" class="sc-ezbkAF fmGXHP"/></button></div><figcaption class="sc-cxpSdN pTDts"><span itemprop="description">Kuvia pahanlaatuisista luomista.</span><span itemprop="copyrightHolder"> Kuva: Yle / Kalle Niskala</span></figcaption></figure><div class="sc-jvvksu qrfSU"><span><span itemscope="" itemtype="http://schema.org/Person" itemprop="author"><span itemprop="name" class="sc-bSqaIl dHDBbk">Tulikukka de Fresnes</span></span></span></div><div class="sc-JEhMO eSjGcE"><div class="sc-itWPBs cjBBhP yle__article__date"><time class="sc-dcgwPl emyLKs yle__article__date--published" datetime="2015-06-10T16:35:10+03:00" itemprop="datePublished">10.6.2015</time><span class="sc-ehIJor eCVJrU">•</span><time class="sc-dcgwPl emyLKs yle__article__date--modified" datetime="2015-06-11T11:35:17+03:00" itemprop="dateModified">Päivitetty 11.6.2015 11:35</time></div><div class="sc-fydGpi fXFxij"><button class="sc-dkQkyq cHhkuI" size="24" aria-label="Jaa artikkeli"><svg aria-label="" fill="#000000" height="24" role="img" viewbox="0 0 24 24" width="24"><path d="M12.7071 2.29289C12.3166 1.90237 11.6834 1.90237 11.2929 2.29289L6.29289 7.29289C5.90237 7.68342 5.90237 8.31658 6.29289 8.70711C6.68342 9.09763 7.31658 9.09763 7.70711 8.70711L11 5.41421V15C11 15.5523 11.4477 16 12 16C12.5523 16 13 15.5523 13 15V5.41421L16.2929 8.70711C16.6834 9.09763 17.3166 9.09763 17.7071 8.70711C18.0976 8.31658 18.0976 7.68342 17.7071 7.29289L12.7071 2.29289ZM4 15C4 14.4477 3.55228 14 3 14C2.44772 14 2 14.4477 2 15V19C2 19.7956 2.31608 20.5587 2.87866 21.1213C3.44128 21.684 4.20437 22 5 22H19C19.7956 22 20.5587 21.6839 21.1213 21.1213C21.6839 20.5587 22 19.7956 22 19V15C22 14.4477 21.5523 14 21 14C20.4477 14 20 14.4477 20 15V19C20 19.2652 19.8947 19.5195 19.7071 19.7071C19.5195 19.8947 19.2652 20 19 20H5C4.73477 20 4.48043 19.8946 4.29292 19.7071C4.10534 19.5195 4 19.2652 4 19V15Z"></path></svg></button></div></div></div><div class="yle__article__content"><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">Pitkälle edenneen melanooman hoidossa on saatu lupaavia tutkimustuloksia yhdistämällä kahta lääkettä. Kehon immuunijärjestelmää aktivoiva nivolumabi pysäyttää syövän etenemisen keskimäärin seitsemän kuukauden ajaksi. Yhdistämällä nivolumabi toiseen samantyyppiseen lääkkeeseen – jo käytössä olevaan ipilimumabiin – melanooman eteneminen pysähtyy keskimäärin lähes vuodeksi.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">Vuosi on pitkä aika, sillä nyt Suomessa käytössä olevat hoitomuodot pysäyttävät pitkälle edenneen melanooman korkeintaan muutamaksi kuukaudeksi.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">Kansainvälisiin tutkimuksiin on osallistunut Suomen yliopistosairaaloissa yli sata etäpesäkkeistä syöpää sairastunutta ihmistä.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">– Tutkimus osoitti todeksi, että yhdistelemällä kahta immunologisesti vaikuttavaa ainetta saadaan parempi tulos kuin yhdellä. Kahden vasta-aineen, nivolumabin ja ipilimumabin yhdistelmä, on tehokkain tunnettu melanooman hoito, toteaa HUS:n Syöpäkeskuksen johtaja Petri Bono.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">Syövän takia kehoa puolustavat valkosolut lamautuvat, eivätkä pysty hoitamaan tehtäväänsä tautien tappajina. Tutkimuksessa on onnistuttu siinä, mitä on jo 90-luvulla yritetty, aktivoimaan elimistön tietyt T-valkosolut hoitamaan myös syöpää.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">– Elimistön omien puolustussolujen aktivointia on yritetty selvittää syövän hoidossa jo 90-luvulta asti, mutta se on ollut vaikeaa. Nyt immunologisilla hoidoilla herätellään puolustussoluja hyökkäämään syöpää vastaan, Bono kertoo.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">Vaikka varhaisvaiheen melanooman ennuste on hyvä, ja 90 prosenttia sairastuneista on elossa viiden vuoden kuluttua taudin havaitsemisesta, hoitamaton ja levinnyt tai uusiutunut melanooma on vaikea hoitaa, siihen kuolee Suomessa vuosittain noin 200 ihmistä.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">Uusia tapauksia diagnosoidaan lisääntyneen auringonoton takia yhä enemmän, Suomessa vuosittain 1 100, USA:ssa 65000. Jokainen palamiskerta jää ihon muistiin ja nostaa riskiä.</p></div><div><h3 class="sc-kfPuZi flMqTE yle__article__heading yle__article__heading--3">Hoito muihinkin syöpiin</h3></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">Kehon immunijärjestelmään vaikuttavien lääkkeiden tehoa tutkitaan myös muiden syöpien hoidossa. HUS:n Petri Bonon mukaan pienisoluinen keuhkosyöpä, virtsarakonsyöpä, munuaissyöpä ja osa suolistosyövistä ovat samantyyppisiä kuin melanooma, joten vastaavat hoidot voivat purra niihinkin. Suomessakin on meneillään laajoja tutkimuksia näissä taudeissa.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">– Immunologiset hoidot näyttävät tulevan klassisten täsmälääkkeiden rinnalle syöpien hoidossa, Bono arvioi.</p></div><div><h3 class="sc-kfPuZi flMqTE yle__article__heading yle__article__heading--3">Sivuvaikutukset rajoittavat</h3></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">Yhdistelmälääkkeen käyttöä vasta tutkitaan. Tutkimusryhmässä potilaita hoitaneen HUS:n ylilääkärin Micaela Hernbergin mukaan yhdistelmälääkkeiden miinuspuoli on sivuvaikutukset, joita tulee lähes kaikille, mutta 70 prosentilla sivuvaikutukset ovat vakavia, osa vaatii sairaalahoitoa ja osalla hoito joudutaan keskeyttämään. Yleisimpiä ovat ihottuma, ripuli ja sisäelintulehdukset.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">– Sivuvaikutukset rajoittavat yhdistelmälääkkeen käyttöä. Emme tiedä vielä hoitomuotojen lopulilsta kokonaisvaikutusta, Hernberg toteaa.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">Nivolumabi tulee EU:ssa markkinoille kesän aikana, USA:ssa se on jo. Nivolumabin sivuvaikutukset yksin ovat pienemmät kuin nyt käytössä olevan ipipimumabin sekä yhdistelmälääkkeen. Sen käyttöönotto tullaan arvioimaan Suomessa sairaanhoitopiirikohtaisesti sen jälkeen, kun lääke läpäisee EU:n viranomaiskäsittelyn tänä vuonna ja tulee myyntiin.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">– Joko nivolumabi tai sen rinnakkaislääke pembrolitsumabi tulee todennäköisesti etäpesäkkeisen melanooman hoitoon myös Suomessa, Petri Bono arvioi.</p></div><div><p class="sc-egiyK sc-bqiRlB ektcFN fGZWCQ yle__article__paragraph">_Otsikkoa on muutettu 11.6.2015: Lääke moninkertaistaa syövän etenemisestä vapaata elinaikaa, ei kokonaiselinaikaa. _</p></div></div><div class="yle__article__footer"><div class="yle__article__links"><p class="sc-eWfVMQ urfEI"><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/3-8055317" class="sc-kTLmzF ftJoIb">Melanooma-ihosyöpä on yleistynyt Yhdysvalloissa hälyttävästi</a><time datetime="2015-06-08T08:01:46" class="sc-dwsnSq ieyzvF">8.6.2015</time></p><p class="sc-eWfVMQ urfEI"><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/3-7914973" class="sc-kTLmzF ftJoIb">Syöpäjärjestöt: Pohjoisessa on muuta maata suurempi riski kuolla ihosyöpään</a><time datetime="2015-04-08T12:53:14" class="sc-dwsnSq ieyzvF">8.4.2015</time></p><p class="sc-eWfVMQ urfEI"><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/3-7911721" class="sc-kTLmzF ftJoIb">Syöpäjärjestö: 1960-luvun etelänmatkat näkyvät nyt ihosyöpinä </a><time datetime="2015-04-06T20:53:10" class="sc-dwsnSq ieyzvF">6.4.2015</time></p></div><div class="sc-jivBlf kOuoPv"><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-212923" class="sc-hZpJaK cCyfDc">tiede</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-209306" class="sc-hZpJaK cCyfDc">terveys</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-30312" class="sc-hZpJaK cCyfDc">syövät</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-1501" class="sc-hZpJaK fclURV">ihosyöpä</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-214540" class="sc-hZpJaK fclURV">lääkkeet</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-205311" class="sc-hZpJaK fclURV">kasvaimet</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-18532" class="sc-hZpJaK fclURV">syöpähoidot</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-220505" class="sc-hZpJaK fclURV">taudit</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-202080" class="sc-hZpJaK fclURV">Helsingin ja Uudenmaan sairaanhoitopiiri (HUS)</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-204379" class="sc-hZpJaK fclURV">ihotaudit</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-187871" class="sc-hZpJaK fclURV">Suomi</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-41831" class="sc-hZpJaK fclURV">lääkeaineiden haittavaikutukset</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-86334" class="sc-hZpJaK fclURV">immunologia</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-834" class="sc-hZpJaK fclURV">sosiaali- ja terveyshallinto</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-215779" class="sc-hZpJaK fclURV">lääketeollisuus</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-154100" class="sc-hZpJaK fclURV">Arvet (Iho)</a><a href="https://web.archive.org/web/20211130005807/https://yle.fi/uutiset/18-10720" class="sc-hZpJaK fclURV">onkologia</a><button class="sc-dkQkyq cHPySI sc-hkgtus cHMzGX" size="48"><svg aria-label="" fill="#000000" height="24" role="img" viewbox="0 0 24 24" width="24"><path d="M13 5C13 4.44772 12.5523 4 12 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eivät tältäkään variantilta anna" src="https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1638217632/13-1-60920798-1638217631715"/></picture></div><div class="PlayButton__Container-sc-1yuazh3-0 iUpHlT"><span class="VisuallyHiddenText-sc-r0pbh8-0 jvcAED">Toista video</span><button type="button" aria-label="Toista video" class="PlayButton__Button-sc-1yuazh3-1 PlayButton__RoundButton-sc-1yuazh3-2 eGndyr csgxgC"><svg viewbox="0 0 24 24" height="16" role="img" aria-hidden="true" color="currentColor" class="PlayButton__RoundIcon-sc-1yuazh3-5 eIZJuE"><use xlink:href="/web/20211130005807im_/https://yle.fi/uutiset/assets/img/icons-v1.svg#play"></use></svg></button></div></div><div class="GridSystem__GridCell-sc-15162af-0 MiniFrontpage__PrimaryHeadlineTextContent-sc-sxba3k-0 fjwYjT ldngWI"><h4 class="Typography-sc-1his0m9-0 MiniFrontpage__StyledHeadline-sc-sxba3k-4 kIJQGM ePooIf link-accent">HUSin Lasse Lehtonen: Uuden rokotteen kehitys omikronmuunnosta vastaan veisi puolesta vuodesta vuoteen</h4><p class="Typography-sc-1his0m9-0 ixVCar"> Lehtosen mukaan tiedossa on “joitakin tapauksia”, joissa omikronmuunnosta ovat muihin maihin tuoneet rokotetut henkilöt.</p><div class="HeadlineMetaData__Container-sc-1n8lae9-0 xyYXn"><time class="DateTime__Time-sc-327z34-0 fNRHDu" aria-label="29.11." datetime="2021-11-29T22:41:37+0200" data-testid="datetime-test-id">29.11.</time><div class="HeadlineMetaData__FluidContainer-sc-1n8lae9-1 hbTLdU"><span class="Tag__Chip-sc-d06pgy-2 grlKv" href="https://yle.fi/uutiset/18-89760">Koronavirus</span></div></div></div></a><div class="MiniFrontpage__SecondaryHeadlinesContainer-sc-sxba3k-2 kkKSKf"><ol class="HeadlineList__List-sc-1u42mwt-0 gxnGaX"><li class="HeadlineList__ListItem-sc-1u42mwt-1 kzvDWD"><a href="/web/20211130005807/https://yle.fi/uutiset/3-12208600" data-testid="miniFrontpage__secondaryHeadline" class="MiniFrontpage__SecondaryHeadlineContainer-sc-sxba3k-5 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srcset="https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_0,y_468,w_5120,h_2880/w_152,h_86,ar_1.7777777777777777,dpr_3,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1638178603/39-88549961a49ec01a77c 3x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_0,y_468,w_5120,h_2880/w_152,h_86,ar_1.7777777777777777,dpr_2,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1638178603/39-88549961a49ec01a77c 2x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_0,y_468,w_5120,h_2880/w_152,h_86,ar_1.7777777777777777,dpr_1,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1638178603/39-88549961a49ec01a77c 1x"/><img class="ResponsiveImage__Img-sc-yvl7gl-0 gpkPTK" alt="Matkustajia Helsinki-Vantaan lentokentällä matkalaukkuineen. 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srcset="https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_12,y_269,w_4902,h_2757/w_152,h_86,ar_1.7777777777777777,dpr_3,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1637768690/39-883503619e4ebf71954 3x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_12,y_269,w_4902,h_2757/w_152,h_86,ar_1.7777777777777777,dpr_2,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1637768690/39-883503619e4ebf71954 2x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_12,y_269,w_4902,h_2757/w_152,h_86,ar_1.7777777777777777,dpr_1,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1637768690/39-883503619e4ebf71954 1x"/><img class="ResponsiveImage__Img-sc-yvl7gl-0 gpkPTK" alt="Hallitus vastasi 24. marraskuuta perussuomalaisten, kokoomuksen, kristillisdemokraattien ja Liike Nyt -puolueen välikysymykseen eduskunnassa." 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srcset="https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_74,h_74,ar_1,dpr_3,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 3x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_74,h_74,ar_1,dpr_2,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 2x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_74,h_74,ar_1,dpr_1,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 1x"/><source media="(min-width: 376px) and (max-width: 767px)" srcset="https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_172,h_172,ar_1,dpr_3,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 3x, 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https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_47,h_47,ar_1,dpr_1,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 1x"/><source media="(min-width: 768px) and (max-width: 1023px)" srcset="https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_68,h_68,ar_1,dpr_3,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 3x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_68,h_68,ar_1,dpr_2,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 2x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_68,h_68,ar_1,dpr_1,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 1x"/><source media="(min-width: 1024px)" srcset="https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_64,h_64,ar_1,dpr_3,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 3x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_64,h_64,ar_1,dpr_2,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 2x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_615,y_0,w_1080,h_1080/w_64,h_64,ar_1,dpr_1,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1612782771/39-77135560211aa48377a 1x"/><img class="ResponsiveImage__Img-sc-yvl7gl-0 gpkPTK" alt="Näin panssarivaunu ajaa Jääkäriprikaatin varushenkilöiden yli – somevideo viritti muistot ja jopa kauhistutti" 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srcset="https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_1314,y_0,w_3840,h_3840/w_64,h_64,ar_1,dpr_3,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1594403023/39-6982275f08a89917fbc 3x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_1314,y_0,w_3840,h_3840/w_64,h_64,ar_1,dpr_2,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1594403023/39-6982275f08a89917fbc 2x, https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_1314,y_0,w_3840,h_3840/w_64,h_64,ar_1,dpr_1,c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1594403023/39-6982275f08a89917fbc 1x"/><img class="ResponsiveImage__Img-sc-yvl7gl-0 gpkPTK" alt="Ghislaine Maxwell." src="https://web.archive.org/web/20211130005807im_/https://images.cdn.yle.fi/image/upload/c_crop,x_0,y_54,w_5760,h_3240/c_fill,g_faces/q_auto:eco,f_auto,fl_lossy/v1594403023/39-6982275f08a89917fbc"/></picture></div></div></a></div></li><li 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Menetelmästä etsitään parannuskeinoa myös muiden syöpien hoitoon.","subjects":[{"id":"18-212923","title":{"fi":"tiede","sv":"vetenskap"}},{"id":"18-209306","title":{"fi":"terveys","sv":"hälsa"}},{"id":"18-30312","title":{"fi":"syövät","sv":"carcinom"}},{"id":"18-1501","title":{"fi":"ihosyöpä","sv":"hudcancer"}},{"id":"18-214540","title":{"fi":"lääkkeet","sv":"mediciner"}},{"id":"18-205311","title":{"fi":"kasvaimet","sv":"tumörer"}},{"id":"18-18532","title":{"fi":"syöpähoidot","sv":"cancerbehandlingar"}},{"id":"18-220505","title":{"fi":"taudit","sv":"sjukdomar"}},{"id":"18-202080","title":{"fi":"Helsingin ja Uudenmaan sairaanhoitopiiri (HUS)","sv":"Helsingfors och Nylands sjukvårdsdistrikt (HUS)"}},{"id":"18-204379","title":{"fi":"ihotaudit","sv":"hudsjukdomar"}},{"id":"18-187871","title":{"fi":"Suomi","sv":"Finland"}},{"id":"18-41831","title":{"fi":"lääkeaineiden haittavaikutukset","sv":"skadeverkningar av läkemedel"}},{"id":"18-86334","title":{"fi":"immunologia","sv":"immunologi"}},{"id":"18-834","title":{"fi":"sosiaali- ja terveyshallinto","sv":"social- och hälsovårdsförvaltning"}},{"id":"18-215779","title":{"fi":"lääketeollisuus","sv":"läkemedelsindustri"}},{"id":"18-154100","title":{"fi":"Arvet (Iho)","sv":"Ärr (Hud)"}},{"id":"18-10720","title":{"fi":"onkologia","sv":"onkologi"}}],"authors":[{"type":"Author","organization":"Yle","some":null,"name":"Tulikukka de Fresnes","id":"3-1565","role":null,"image":{"type":"ImageBlock","id":"13-3-8271007","alt":"Tulikukka De Fresnes","aspect":1.7777777910232544,"caption":"Tulikukka De Fresnes","source":"Jyrki Lyytikkä \u002F Yle","recommendedFormat":"jpg","width":null,"height":null,"crops":null},"description":[]}],"format":null,"journalisticStyle":null,"live":null,"datePublished":"2015-06-10T16:35:10+0300","dateContentModified":"2015-06-11T11:35:17+0300","topic":null,"mainMedia":[{"type":"ImageBlock","id":"13-3-7449358","alt":"Kuvassa erilaisia luomien muutoksia.","aspect":1.7777777910232544,"caption":"Kuvia pahanlaatuisista luomista.","source":"Yle \u002F Kalle Niskala","recommendedFormat":"jpg","width":null,"height":null,"crops":null}],"properties":["importance:normal","uutisvahti:enabled"],"content":[{"type":"HeadingBlock","level":1,"text":"Uusi melanoomalääke pidentää syöpäsairaan elinaikaa "},{"type":"TextBlock","markdown":"Uudentyyppiset immunologiset syöpälääkkeet aktivoivat elimistön omat valkosolut hyökkäämään syöpäsoluja vastaan. Menetelmästä etsitään parannuskeinoa myös muiden syöpien hoitoon."},{"type":"ImageBlock","id":"13-3-7449358","alt":"Kuvassa erilaisia luomien muutoksia.","aspect":1.7777777910232544,"caption":"Kuvia pahanlaatuisista luomista.","source":"Yle \u002F Kalle Niskala","recommendedFormat":"jpg","width":null,"height":null,"crops":null},{"type":"TextBlock","markdown":"Pitkälle edenneen melanooman hoidossa on saatu lupaavia tutkimustuloksia yhdistämällä kahta lääkettä. Kehon immuunijärjestelmää aktivoiva nivolumabi pysäyttää syövän etenemisen keskimäärin seitsemän kuukauden ajaksi. Yhdistämällä nivolumabi toiseen samantyyppiseen lääkkeeseen – jo käytössä olevaan ipilimumabiin – melanooman eteneminen pysähtyy keskimäärin lähes vuodeksi."},{"type":"TextBlock","markdown":"Vuosi on pitkä aika, sillä nyt Suomessa käytössä olevat hoitomuodot pysäyttävät pitkälle edenneen melanooman korkeintaan muutamaksi kuukaudeksi."},{"type":"TextBlock","markdown":"Kansainvälisiin tutkimuksiin on osallistunut Suomen yliopistosairaaloissa yli sata etäpesäkkeistä syöpää sairastunutta ihmistä."},{"type":"TextBlock","markdown":"– Tutkimus osoitti todeksi, että yhdistelemällä kahta immunologisesti vaikuttavaa ainetta saadaan parempi tulos kuin yhdellä. Kahden vasta-aineen, nivolumabin ja ipilimumabin yhdistelmä, on tehokkain tunnettu melanooman hoito, toteaa HUS:n Syöpäkeskuksen johtaja Petri Bono."},{"type":"TextBlock","markdown":"Syövän takia kehoa puolustavat valkosolut lamautuvat, eivätkä pysty hoitamaan tehtäväänsä tautien tappajina. Tutkimuksessa on onnistuttu siinä, mitä on jo 90-luvulla yritetty, aktivoimaan elimistön tietyt T-valkosolut hoitamaan myös syöpää."},{"type":"TextBlock","markdown":"– Elimistön omien puolustussolujen aktivointia on yritetty selvittää syövän hoidossa jo 90-luvulta asti, mutta se on ollut vaikeaa. Nyt immunologisilla hoidoilla herätellään puolustussoluja hyökkäämään syöpää vastaan, Bono kertoo."},{"type":"TextBlock","markdown":"Vaikka varhaisvaiheen melanooman ennuste on hyvä, ja 90 prosenttia sairastuneista on elossa viiden vuoden kuluttua taudin havaitsemisesta, hoitamaton ja levinnyt tai uusiutunut melanooma on vaikea hoitaa, siihen kuolee Suomessa vuosittain noin 200 ihmistä."},{"type":"TextBlock","markdown":"Uusia tapauksia diagnosoidaan lisääntyneen auringonoton takia yhä enemmän, Suomessa vuosittain 1 100, USA:ssa 65000. Jokainen palamiskerta jää ihon muistiin ja nostaa riskiä."},{"type":"HeadingBlock","level":3,"text":"Hoito muihinkin syöpiin"},{"type":"TextBlock","markdown":"Kehon immunijärjestelmään vaikuttavien lääkkeiden tehoa tutkitaan myös muiden syöpien hoidossa. HUS:n Petri Bonon mukaan pienisoluinen keuhkosyöpä, virtsarakonsyöpä, munuaissyöpä ja osa suolistosyövistä ovat samantyyppisiä kuin melanooma, joten vastaavat hoidot voivat purra niihinkin. Suomessakin on meneillään laajoja tutkimuksia näissä taudeissa."},{"type":"TextBlock","markdown":"– Immunologiset hoidot näyttävät tulevan klassisten täsmälääkkeiden rinnalle syöpien hoidossa, Bono arvioi."},{"type":"HeadingBlock","level":3,"text":"Sivuvaikutukset rajoittavat"},{"type":"TextBlock","markdown":"Yhdistelmälääkkeen käyttöä vasta tutkitaan. Tutkimusryhmässä potilaita hoitaneen HUS:n ylilääkärin Micaela Hernbergin mukaan yhdistelmälääkkeiden miinuspuoli on sivuvaikutukset, joita tulee lähes kaikille, mutta 70 prosentilla sivuvaikutukset ovat vakavia, osa vaatii sairaalahoitoa ja osalla hoito joudutaan keskeyttämään. Yleisimpiä ovat ihottuma, ripuli ja sisäelintulehdukset."},{"type":"TextBlock","markdown":"– Sivuvaikutukset rajoittavat yhdistelmälääkkeen käyttöä. Emme tiedä vielä hoitomuotojen lopulilsta kokonaisvaikutusta, Hernberg toteaa."},{"type":"TextBlock","markdown":"Nivolumabi tulee EU:ssa markkinoille kesän aikana, USA:ssa se on jo. Nivolumabin sivuvaikutukset yksin ovat pienemmät kuin nyt käytössä olevan ipipimumabin sekä yhdistelmälääkkeen. Sen käyttöönotto tullaan arvioimaan Suomessa sairaanhoitopiirikohtaisesti sen jälkeen, kun lääke läpäisee EU:n viranomaiskäsittelyn tänä vuonna ja tulee myyntiin."},{"type":"TextBlock","markdown":"– Joko nivolumabi tai sen rinnakkaislääke pembrolitsumabi tulee todennäköisesti etäpesäkkeisen melanooman hoitoon myös Suomessa, Petri Bono arvioi."},{"type":"TextBlock","markdown":"_Otsikkoa on muutettu 11.6.2015: Lääke moninkertaistaa syövän etenemisestä vapaata elinaikaa, ei kokonaiselinaikaa. _"},{"type":"LinksBlock","links":[{"title":"Melanooma-ihosyöpä on yleistynyt Yhdysvalloissa hälyttävästi","internal":{"id":"3-8055317","datePublished":"2015-06-08T08:01:46"},"external":{"url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F3-8055317","source":null}},{"title":"Syöpäjärjestöt: Pohjoisessa on muuta maata suurempi riski kuolla ihosyöpään","internal":{"id":"3-7914973","datePublished":"2015-04-08T12:53:14"},"external":{"url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F3-7914973","source":null}},{"title":"Syöpäjärjestö: 1960-luvun etelänmatkat näkyvät nyt ihosyöpinä ","internal":{"id":"3-7911721","datePublished":"2015-04-06T20:53:10"},"external":{"url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F3-7911721","source":null}}]}],"sources":null,"places":null},"supplements":{"topHeadlines":[{"uuid":"ec5a3e91-5155-11ec-85bb-b1e028bc33c4","type":"article","url":"\u002Fuutiset\u002F3-12209214","size":null,"texts":{"headline":{"text":"HUSin Lasse Lehtonen: Uuden rokotteen kehitys omikronmuunnosta vastaan veisi puolesta vuodesta vuoteen"},"lead":{"text":" Lehtosen mukaan tiedossa on “joitakin tapauksia”, joissa omikronmuunnosta ovat muihin maihin tuoneet rokotetut henkilöt."}},"image":{"id":"13-1-60920798-1638217631715","alt":"HUSin Lasse Lehtonen: Täydellistä suojaa rokotukset eivät tältäkään variantilta anna","version":1638217632,"blurhash":null,"crops":[],"template":null},"isABTestOn":false,"variantId":"a","theme":null,"contentId":"3-12209214","format":null,"journalisticStyle":null,"hideSummary":null,"hideViewerCount":null,"breakingNews":null,"journalistDriven":null,"customKicker":null,"video":{"id":"1-60920798","aspectRatio":{"width":16,"height":9}},"publishedAt":"2021-11-29T22:41:37+0200","contentModifiedAt":"2021-11-29T22:41:37+0200","relatedHeadlines":null,"concepts":[{"id":"18-89760","text":"Koronavirus","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-89760"},{"id":"18-315684","text":"Koronarokote","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-315684"},{"id":"18-211142","text":"Rokotteet","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-211142"},{"id":"18-218731","text":"Tartuntataudit","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-218731"},{"id":"18-196501","text":"A-studio","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-196501"}],"topic":null,"byline":{"name":"Ines Sirén","description":null,"image":null},"livefeed":null,"specialTopic":null},{"uuid":"96b67721-5140-11ec-a369-237576b9ec33","type":"article","url":"\u002Fuutiset\u002F3-12208600","size":null,"texts":{"headline":{"text":"Tutkija näkee uudessa omikronmuunnoksessa huolestuttavia merkkejä – STM:n Puumalainen: Tuskin vaikuttaa kotimaan jouluun"},"lead":{"text":"Terveysturvallisuuden asiantuntijan Taneli Puumalaisen mukaan ei ole vielä varmaa, että uusi omikronmuunnos leviää Suomeen. 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Rekrytointipalvelun tavoitteena on helpottaa osaajien työllistymistä talousalueen yrityksiin."}},"image":{"id":"39-88464561a0b8de30493","alt":"Restonomiopiskelija Jori Julkunen baasitiskin takana. 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Hakolalle voi tulla parin kylkiluun murtuman takia kuukausi taukoa hiihdosta. Olympialaisiin on aikaa reilut kaksi kuukautta."}},"image":{"id":"13-67-aa716354861d495080d414a2eb354986","alt":"Ristomatti Hakola kertoi lääkärin tuomion","version":1638203730,"blurhash":null,"crops":null},"video":{"id":"1-60920719"},"publishedAt":"2021-11-29T18:25:24+0200","concepts":[{"id":"18-219772","text":"Hiihto","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-219772"},{"id":"18-220090","text":"Urheilu","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-220090"},{"id":"18-217673","text":"Hiihtolajit","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-217673"},{"id":"18-153120","text":"Ristomatti Hakola","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-153120"},{"id":"18-149004","text":"Pohjoismaiset hiihtolajit","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-149004"}]},{"contentId":"3-12208927","type":"article","url":"\u002Fuutiset\u002F3-12208927","texts":{"headline":{"text":"Hallitus harkitsee alueiden patistelua lisärajoituksiin ohjauskirjeellä – neuvottelee koronatilanteesta tiistaina"},"lead":{"text":"Hallituksen odotetaan patistelevan alueita lisärajoitustoimiin, jotta heikentynyt koronatilanne saataisiin Suomessa hallintaan. Erityistä huolta hallituksessa aiheuttaa uusi omikronmuunnos."}},"image":{"id":"39-883503619e4ebf71954","alt":"Hallitus vastasi 24. marraskuuta perussuomalaisten, kokoomuksen, kristillisdemokraattien ja Liike Nyt -puolueen välikysymykseen eduskunnassa.","version":1637768690,"blurhash":"L2846+9^01#R8Iog#R$z00=|-pAD","crops":[{"aspect":1.78,"coordinates":{"height":2757,"width":4902,"x":12,"y":269}},{"aspect":0.67,"coordinates":{"height":3277,"width":2184,"x":2137,"y":0}},{"aspect":1,"coordinates":{"height":3277,"width":3277,"x":198,"y":0}},{"aspect":2.5,"coordinates":{"height":1966,"width":4915,"x":0,"y":825}}]},"publishedAt":"2021-11-29T18:22:07+0200","concepts":[{"id":"18-89760","text":"Koronavirus","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-89760"},{"id":"18-323956","text":"Koronarajoitukset","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-323956"},{"id":"18-197020","text":"Sosiaali- ja terveysministeriö","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-197020"},{"id":"18-220306","text":"Politiikka","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-220306"},{"id":"18-179403","text":"Terveyden ja hyvinvoinnin laitos","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-179403"},{"id":"18-5720","text":"Sairaanhoitopiirit","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-5720"},{"id":"18-328536","text":"Koronapassi","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-328536"},{"id":"18-211142","text":"Rokotteet","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-211142"},{"id":"18-17808","text":"Aluehallintovirastot","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-17808"},{"id":"18-218788","text":"Hallitukset","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-218788"},{"id":"18-187871","text":"Suomi","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-187871"}]},{"contentId":"3-12208712","type":"article","url":"\u002Fuutiset\u002F3-12208712","texts":{"headline":{"text":"Neuvottelut Iranin ydinsopimuksesta käynnistyivät uudelleen – tuloksia saatetaan kuitenkin odottaa vielä pitkään, sillä Iran on valinnut tiukan linjan"},"lead":{"text":"Viimeksi kesäkuussa käydyissä neuvotteluissa diplomaatit olivat toiveikkaita Iranin suhteen, mutta tilanne on muuttunut kesän jälkeen. "}},"image":{"id":"39-88577161a4ebc162de6","alt":"Ebrahim Raisi","version":1638198346,"blurhash":"LJCsjYkCD*xa~poyt7aeE1xt-:IV","crops":[{"aspect":1.78,"coordinates":{"height":759,"width":1350,"x":0,"y":119}},{"aspect":0.67,"coordinates":{"height":1750,"width":1166,"x":116,"y":1}},{"aspect":1,"coordinates":{"height":1350,"width":1350,"x":0,"y":70}},{"aspect":2.5,"coordinates":{"height":540,"width":1350,"x":0,"y":121}}]},"publishedAt":"2021-11-29T18:10:47+0200","concepts":[{"id":"18-194063","text":"Iran","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-194063"},{"id":"18-34953","text":"Ulkomaat","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-34953"},{"id":"18-218620","text":"Ydinaseet","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-218620"},{"id":"18-210619","text":"Ydintekniikka","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-210619"},{"id":"18-193507","text":"Yhdysvallat","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-193507"},{"id":"18-168817","text":"Kiina","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-168817"},{"id":"18-185583","text":"Lähi-itä","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-185583"},{"id":"18-69766","text":"Uraanin rikastaminen","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-69766"},{"id":"18-84118","text":"IAEA","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-84118"}]},{"contentId":"3-12208819","type":"article","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Furheilu\u002F3-12208819","texts":{"headline":{"text":"Voiko rokottamaton urheilija päästä Pekingin olympialaisiin? Näin vastaa olympiakomitea: \"Käytäntö tekee sen mahdottomaksi\""},"lead":{"text":"Suomen joukkueella ei ole vaatimusta rokotuksista, mutta rokottamaton urheilija joutuisi 2-3 viikoksi hotellikaranteeniin Pekingissä. "}},"image":{"id":"39-5522225c9cd8f986ab8","alt":"Mika Lehtimäki.","version":1553783078,"blurhash":null,"crops":[{"aspect":1.78,"coordinates":{"height":3113,"width":5535,"x":0,"y":35}},{"aspect":0.67,"coordinates":{"height":3560,"width":2373,"x":1730,"y":0}},{"aspect":1,"coordinates":{"height":2525,"width":2525,"x":1764,"y":0}},{"aspect":2.5,"coordinates":{"height":2214,"width":5535,"x":0,"y":320}}]},"publishedAt":"2021-11-29T18:02:40+0200","concepts":[{"id":"18-210936","text":"Olympialaiset","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-210936"},{"id":"18-220090","text":"Urheilu","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-220090"},{"id":"18-83264","text":"Urheilutapahtumat","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-83264"},{"id":"18-174830","text":"Peking","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-174830"},{"id":"18-220588","text":"Talviolympialaiset","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-220588"},{"id":"18-211068","text":"Talviurheilu","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-211068"},{"id":"18-219772","text":"Hiihto","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-219772"},{"id":"18-217673","text":"Hiihtolajit","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-217673"},{"id":"18-217877","text":"Lumilautailu","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-217877"},{"id":"18-169085","text":"Kansainvälinen olympiakomitea (KOK)","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-169085"},{"id":"18-149004","text":"Pohjoismaiset hiihtolajit","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-149004"}]},{"contentId":"3-12209012","type":"article","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Furheilu\u002F3-12209012","texts":{"headline":{"text":"Suomalaisittain harvinaisen MM-mitalin voittaneen Niclas Grönholmin tulevaisuuden kuviot auki – siirtyminen täyssähköautoihin kaukana mutkattomasta"},"lead":{"text":"Niclas Grönholm jää rallicrossin MM-sarjaan viimeisenä polttomoottoriautoilla ajetun MM-osakilpailun voittajana. Grönholm nappasi kauden päätöskilpailun voitolla MM-pronssia. Aiemmin suomalaisista mitaleille oli yltänyt vain Topi Heikkinen."}},"image":{"id":"39-88578661a4f251df004","alt":"Niclas Grönholm tuuletti Nürbugringillä voittoa ja MM-pronssia.","version":1638199924,"blurhash":"LEE{t|%%1Oq@PAZ~vfX:E3xvRNM{","crops":[{"aspect":1.78,"coordinates":{"height":1687,"width":3000,"x":0,"y":300}},{"aspect":0.67,"coordinates":{"height":2000,"width":1333,"x":1021,"y":0}},{"aspect":1,"coordinates":{"height":2000,"width":2000,"x":689,"y":0}},{"aspect":2.5,"coordinates":{"height":1200,"width":3000,"x":0,"y":342}}]},"publishedAt":"2021-11-29T17:41:19+0200","concepts":[{"id":"18-138896","text":"Rallicross","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-138896"},{"id":"18-220090","text":"Urheilu","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-220090"},{"id":"18-186857","text":"Niclas Grönholm","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-186857"}]},{"contentId":"3-12208609","type":"article","url":"\u002Fuutiset\u002F3-12208609","texts":{"headline":{"text":"Omikron sekoitti Arto Haapalan työmatkan Etelä-Afrikassa – odottaa nyt karanteenissa kotiinpääsyä vantaalaisessa hotellissa"},"lead":{"text":"Etelä-Pohjanmaalla Kuortaneella asuva Arto Haapala palasi sunnuntaina työmatkalta Etelä-Afrikasta. Hän on yksi niistä matkustajista, jotka joutuvat käymään läpi pakollisen terveystarkastuksen Helsinki-Vantaan kentällä. "}},"image":{"id":"13-1-60919709-1638194263443","alt":"Helsinki-Vantaalla eteläisestä Afrikasta saapuneet matkustajat ohjataan pakolliseen terveystarkastukseen","version":1638194264,"blurhash":null,"crops":null},"video":{"id":"1-60919709"},"publishedAt":"2021-11-29T17:35:00+0200","concepts":[{"id":"18-89760","text":"Koronavirus","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-89760"},{"id":"18-209653","text":"Terveystarkastukset","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-209653"},{"id":"18-220149","text":"Karanteeni","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-220149"},{"id":"18-181469","text":"Kuortane","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-181469"},{"id":"18-187871","text":"Suomi","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-187871"},{"id":"18-170954","text":"Etelä-Afrikka","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-170954"},{"id":"18-172636","text":"Helsinki-Vantaan lentoasema","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-172636"},{"id":"18-206851","text":"Matkailu","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-206851"},{"id":"18-164131","text":"Suomeen matkustaminen","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-164131"}]},{"contentId":"3-12208605","type":"article","url":"\u002Fuutiset\u002F3-12208605","texts":{"headline":{"text":"Mitä haluaisit tietää uudesta omikronmuunnoksesta? Ehdota kysymyksiä, etsimme niihin vastaukset"},"lead":{"text":"THL:n mukaan myös Suomesta on löytynyt kaksi näytettä, joissa saattaa olla kyse virusmuunnoksesta. Testien tuloksia odotetaan. Mikä variantissa sinua mietityttää?"}},"image":{"id":"39-88522961a30ec89c01d","alt":"Ihmiset jonottavat koronavirusnäytteenottopaikkaan Münchenin lentokentällä.","version":1638076217,"blurhash":"LCHVSUyZ00zm~qtStSnhS_aenh%$","crops":[{"aspect":1.78,"coordinates":{"height":1406,"width":2500,"x":0,"y":54}},{"aspect":0.67,"coordinates":{"height":1659,"width":1106,"x":1126,"y":7}},{"aspect":1,"coordinates":{"height":1659,"width":1659,"x":675,"y":7}}]},"publishedAt":"2021-11-29T16:36:19+0200","concepts":[{"id":"18-89760","text":"Koronavirus","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-89760"},{"id":"18-309412","text":"Koronaviruksen aiheuttama sairaus","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-309412"},{"id":"18-310099","text":"Koronapandemia","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-310099"},{"id":"18-310307","text":"Varmistetut koronavirustartunnat","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-310307"},{"id":"18-323956","text":"Koronarajoitukset","url":"https:\u002F\u002Fweb.archive.org\u002Fweb\u002F20211130005807\u002Fhttps:\u002F\u002Fyle.fi\u002Fuutiset\u002F18-323956"}]},{"contentId":"3-12208283","type":"article","url":"\u002Fuutiset\u002F3-12208283","texts":{"headline":{"text":"Visionääri Kanye Westin ja Louis Vuittonin takana, DJ ja aktivisti – tällaisen jäljen edesmennyt Virgil Abloh jätti muotimaailmaan"},"lead":{"text":"Virgil Abloh tunnettiin muun muassa perustamastaan Off-White-vaatemerkistä. 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