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Search results for: Yongan Yu
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Yongan Yu</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> mRNA Biomarkers of Mechanical Asphyxia-Induced Death in Cardiac Tissue</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yan%20Zeng">Yan Zeng</a>, <a href="https://publications.waset.org/abstracts/search?q=Li%20Tao"> Li Tao</a>, <a href="https://publications.waset.org/abstracts/search?q=Liujun%20Han"> Liujun Han</a>, <a href="https://publications.waset.org/abstracts/search?q=Tianye%20Zhang"> Tianye Zhang</a>, <a href="https://publications.waset.org/abstracts/search?q=Yongan%20Yu"> Yongan Yu</a>, <a href="https://publications.waset.org/abstracts/search?q=Kaijun%20Ma"> Kaijun Ma</a>, <a href="https://publications.waset.org/abstracts/search?q=Long%20Chen"> Long Chen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Mechanical asphyxia is one of the main cause of death; however, death by mechanical asphyxia may be difficult to prove in court, particularly in cases in which corpses exhibit no obvious signs of asphyxia. To identify a credible biomarker of asphyxia, we first examined the expression levels of all the mRNAs in human cardiac tissue specimens subjected to mechanical asphyxia and compared these expression levels with those of the corresponding mRNAs in specimens subjected to craniocerebral injury. A total of 119 differentially expressed mRNAs were selected and the expression levels of these mRNAs were examined in 44 human cardiac tissue specimens subjected to mechanical asphyxia, craniocerebral injury, hemorrhagic shock and other causes of death. We found that DUSP1 and KCNJ2 were up-regulated in tissue specimens of mechanical asphyxia compared with control tissues, with no significant correlation between age, environmental temperature and PMI, indicating that DUSP1 and KCNJ2 may associate with mechanical asphyxia-induced death and can thus serve as useful biomarkers of death by mechanical asphyxia. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mechanical%20asphyxia" title="mechanical asphyxia">mechanical asphyxia</a>, <a href="https://publications.waset.org/abstracts/search?q=biomarkers" title=" biomarkers"> biomarkers</a>, <a href="https://publications.waset.org/abstracts/search?q=DUSP1" title=" DUSP1"> DUSP1</a>, <a href="https://publications.waset.org/abstracts/search?q=KCNJ2" title=" KCNJ2"> KCNJ2</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac%20tissue" title=" cardiac tissue"> cardiac tissue</a> </p> <a href="https://publications.waset.org/abstracts/62627/mrna-biomarkers-of-mechanical-asphyxia-induced-death-in-cardiac-tissue" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/62627.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">295</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div 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