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Edentulism May Heighten Sleep Apnea Risk
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width="1.25rem" xmlns="http://www.w3.org/2000/svg"><polyline points="6 9 6 2 18 2 18 9"></polyline><path d="M6 18H4a2 2 0 0 1-2-2v-5a2 2 0 0 1 2-2h16a2 2 0 0 1 2 2v5a2 2 0 0 1-2 2h-2"></path><rect x="6" y="14" width="12" height="8"></rect></svg></a></button></div></div><div><div class="flex flex-wrap"><p class=" text-primary font-semibold">News</p><div class="h-[16px] border-l-2 border-gray-400 mt-1 mx-1"></div><p class=" text-primary font-semibold">Article</p><div class="h-[16px] border-l-2 border-gray-400 mt-1 mx-1 "></div><time class="text-gray-500 " dateTime="2024-11-23T15:00:00.000">November 23, 2024</time></div><h1 class="text-[26px] font-medium leading-8">Edentulism May Heighten Sleep Apnea Risk</h1><div class="py-3 text-gray-600 md:flex flex-col md:justify-between"><div class="flex flex-col xs:flex-row"><p class="mr-1 self-start">Author(s):</p><div class="flex flex-col xs:flex-row mb-3 md:mb-0"><div class="flex flex-wrap"><span class="text-md mr-2"><a class="text-author text-gray-500 hover:text-primary underline hover:no-underline decoration-gray-400" href="/authors/jared-kaltwasser">Jared Kaltwasser</a></span></div></div></div><div class="max-w-full"><div class="flex flex-wrap sm:flex-nowrap items-center w-fit my-2"></div><div class="w-full flex flex-col sm:flex-row justify-between mt-2"><div class="block md:hidden "><div class="mt-2 flex items-center max-w-fit"><button title="Edentulism May Heighten Sleep Apnea Risk" aria-label="facebook" class="react-share__ShareButton" style="background-color:transparent;border:none;padding:0;font:inherit;color:inherit;cursor:pointer"><svg viewBox="0 0 64 64" width="32" height="32"><circle cx="32" cy="32" r="31" fill="#3b5998"></circle><path d="M34.1,47V33.3h4.6l0.7-5.3h-5.3v-3.4c0-1.5,0.4-2.6,2.6-2.6l2.8,0v-4.8c-0.5-0.1-2.2-0.2-4.1-0.2 c-4.1,0-6.9,2.5-6.9,7V28H24v5.3h4.6V47H34.1z" fill="white"></path></svg></button><button aria-label="twitter" class="react-share__ShareButton" 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2px; } audio { height: 40px; } .rhap_container { width: 300px !important; border-radius: 100px !important; height: 40px !important; box-shadow: 0px 0px 2px 2px rgba(0,0,0,0.1); } .rhap_progress-section { width: 150px; margin-left: 35px; } .rhap_controls-section { position: relative; bottom: .75rem; } .rhap_time { font-size: 12px; color: rgb(0,55,103); } .rhap_progress-bar { color: rgb(0,55,103) !important; } .rhap_progress-filled { background-color: rgb(0,55,103) !important; } .rhap_progress-indicator { height: 15px; width: 5px; top: -5px; margin-left: 1px; background-color: rgb(0,55,103) !important; } .rhap_repeat-button { display: none; } .rhap_volume-bar, rhap_volume-button, .rhap_volume-indicator { background: rgb(0,55,103) !important; } .rhap_volume-bar { height: 2px; width: 35px; position: relative; left: 22px; bottom: 21px; } .rhap_volume-button { // width: 5px; // height: 5px; flex: 0 0 26px; position: relative; left: 22px; bottom: 21px; } .rhap_volume-button svg { height: 18px; width: 18px; } .rhap_volume-indicator { height: 8px; width: 8px; top: -2.75px } .rhap_button-clear { color: rgb(0,55,103) !important; } .rhap_play-pause-button { color: rgb(0,55,103) !important; font-size: 30px !important; width: 30px !important; height: 30px !important; position: relative; right: 90px; bottom: 22px; } .rhap_main-controls button { color: rgb(0,55,103) !important; } audio::-webkit-media-controls-play-button, video::-webkit-media-controls-play-button { -webkit-appearance: media-play-button; color: #b8dcf6; } audio::-webkit-media-controls-panel { background-color: white !important; color: #000; } audio::-webkit-media-controls-current-time-display, audio::-webkit-media-controls-time-remaining-display { font-size: 12px; } </style></div></div></div><div class=" lg:w-full flex flex-col lg:flex-row lg:items-center lg:justify-end"></div><div class="w-full flex flex-col px-4 py-4 border-t border-b border-solid border-gray-400 my-4 "><h3 class="text-primary text-xl font-semibold">Key Takeaways</h3><ul class="list-disc px-8"><li class="py-2 "> Edentulism may increase obstructive sleep apnea risk due to anatomical changes affecting the upper airway's size and function. </li><li class="py-2 "> Studies unanimously associate edentulism with higher Apnea-Hypopnea Index scores, but more research is needed for robust conclusions. </li><li class="py-2 hidden"> The impact of dentures on OSA risk is inconclusive, with studies showing both increased risk and improved airway space. </li><li class="py-2 hidden"> Emphasizing prosthodontic management and tooth loss prevention is crucial, given the plausible edentulism-OSA association.</li></ul><span class="text-xs font-bold text-primary underline cursor-pointer mt-2 ml-4">SHOW MORE</span></div><p class="py-2 mb-2 text-sm italic text-gray-600">A systematic review has found a potential link between edentulism and sleep apnea risk, although the authors said differences in study designs prohibited a meta-analysis.</p><div class="py-2"><div class="blockText_blockContent__TbCXh"><p class="pb-2"></p><p class="pb-2">Anatomical alterations associated with tooth loss, also known as edentulism, appear to increase the risk of <a target="_blank" href="https://www.ajmc.com/compendium/sleep">obstructive sleep apnea</a> (OSA), according to a new systematic review.1The report, which was <a rel="nofollow noreferrer noopener" target="_blank" href="https://onlinelibrary.wiley.com/doi/10.1111/jopr.13981">published in <em>Journal of Prosthodontics</em></a><em>, </em>found unanimous agreement on the link, although the impact of remedies such as dentures remains unclear.</p><p class="pb-2"></p><p class="pb-2">Left untreated, and often undiagnosed, OSA can lead to several concerning comorbidities, including hypertension, diabetes, and impaired cognitive function, noted the study authors. A <a rel="nofollow noreferrer noopener" target="_blank" href="https://jcsm.aasm.org/doi/10.5664/jcsm.9738">study published in 2022</a> found that the high rate of undiagnosed OSA is tied to a lack of coordination of care, negative perceptions about the disease, and a belief among patients that their OSA symptoms are not serious enough to warrant medical care.<sup class="text-inherit">2</sup></p><p class="pb-2"></p><p class="pb-2">The authors noted that although most sleep-related disorders are treated by medical doctors, some sleep issues can be related to the dental field.</p><p class="pb-2"></p><p class="pb-2">“Oral care may be influenced by OSA and there have already been studies concerning the association of OSA with increased prevalence of periodontal disease, as well as with tooth wear, orofacial pain, and xerostomia,” they wrote.</p><p class="pb-2"></p><div class=""><div style="width:35%;float:Right;max-width:525px;margin:0 auto 1rem;clear:both;cursor:" class=" figure"><div class="flex-none relative text-center"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%271200%27%20height=%27738%27/%3e"/></span><img alt="Tooth loss | Image Credit: © valiantsin-stock.adobe.com" title="Tooth loss | Image Credit: © valiantsin-stock.adobe.com" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Tooth loss | Image Credit: © valiantsin-stock.adobe.com" title="Tooth loss | Image Credit: © valiantsin-stock.adobe.com" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fd8405a2a194a2c5f871d2c521ca31d0ec29d29bc-1200x738.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1x, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fd8405a2a194a2c5f871d2c521ca31d0ec29d29bc-1200x738.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 2x" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fajmc%2Fd8405a2a194a2c5f871d2c521ca31d0ec29d29bc-1200x738.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div id="image-caption" class="text-gray-500 italic"><div class="blockText_blockContent__TbCXh"><p class="pb-2">Explaining their findings, the authors of this study noted that although most sleep-related disorders are treated by medical doctors, some sleep issues can be related to the dental field. | Image Credit: © valiantsin-stock.adobe.com</p></div></div><div class="top-[-100%] block w-[1px] transition-opacity duration-500 ease-in-out opacity-0 overflow-hidden"><img class="m-auto absolute inset-0 max-w-[0%] max-h-[0%] border-[3px] border-solid border-white shadow-[0px_0px_8px_rgba(0,0,0,0.3)] box-border transition ease-in-out duration-500" src="https://cdn.sanity.io/images/0vv8moc6/ajmc/d8405a2a194a2c5f871d2c521ca31d0ec29d29bc-1200x738.jpg?fit=crop&auto=format"/></div></div><style> #image-caption p{ font-size: 12px; max-width: 525px; margin: 0 auto; text-align: center; } </style></div><p class="pb-2">The link between edentulism and OSA has been studied for a number of years, in part because complete tooth loss has already been associated with diseases including periodontitis, oral cancer, and trauma, they noted. Moreover, the loss of teeth can spark anatomical changes affecting the size and function of the upper airway.</p><p class="pb-2"></p><p class="pb-2">“Changes that are also frequently observed include loss of the vertical dimension of occlusion, mandibular rotation, and reduction of the lower face height,” they wrote. “Increased collapsibility of the pharynx can act as a causal factor for OSA.”</p><p class="pb-2"></p><p class="pb-2">They wanted to better understand what the existing scientific literature says about links between OSA and edentulism, and see what conclusions—if any—could be drawn, so they searched a number of scientific databases for relevant studies investigating potential links between OSA and edentulism. They found 23 such studies, published between from 1999 to 2023, all of which were clinical studies and 6 of which were randomized controlled trials.</p><p class="pb-2"></p><p class="pb-2">The studies were unanimous in concluding that there is an association between edentulism and OSA, the authors found. They suggest that Apnea-Hypopnea Index scores were 2 to 3 times higher in people with edentulism than people with teeth. However, the authors cautioned that there were relatively few data directly comparing edentulous and dentate patients, which they said indicates a need for more research into the question. They also said differences in study methods, OSA diagnostic tools, and outcome criteria made it impossible to do a meta-analysis.</p><p class="pb-2"></p><p class="pb-2">Another question that has been evaluated is the impact of dentures on OSA risk. The existing research is inconclusive, they noted, with some studies suggesting that dentures can increase the risk of OSA and other studies finding that dentures decrease the risk. A <a rel="nofollow noreferrer noopener" target="_blank" href="https://dentjods.sums.ac.ir/article_48879.html">more recent study</a> that looked specifically at implant-supported mandibular dentures, however, found they can improve airway space and symptoms in people with mild to moderate OSA.<sup class="text-inherit">3</sup></p><p class="pb-2"></p><p class="pb-2">The authors said the data show a “plausible” association between edentulism and OSA, which they said underscores the importance of prosthodontic management and the prevention of tooth loss.</p><p class="pb-2"></p><p class="pb-2">“However, clinical data are limited and heterogenous, so more clinical studies should be encouraged for more robust conclusions,” they wrote.</p><p class="pb-2"></p><p class="pb-2"><strong>References</strong></p><p class="pb-2">1. Pachiou A, Roulias P, Steiropoulos P, Halazonetis DJ, Kourtis S. Association of edentulism and obstructive sleep apnea: a systematic review. <em>J Prosthodont</em>. Published online November 13, 2024. doi:10.1111/jopr.13981</p><p class="pb-2">2. Ye L, Li W, Willis DG. Facilitators and barriers to getting obstructive sleep apnea diagnosed: perspectives from patients and their partners. <em>J Clin Sleep Med</em>. 2022;18(3):835-841. doi:10.5664/jcsm.9738</p><p class="pb-2">3. Krishnamurthy P, Maheswari U, Mohamed K. Effect of prosthetic rehabilitation on airway space in edentulous patients with obstructive sleep apnea- a preliminary observational study. <em>J Dent (Shiraz)</em>. 2023;24(4):382-388. doi:10.30476/dentjods.2022.95716.1886</p><p class="pb-2"></p></div></div><div class="flex items-center lg:w-3/4 mb-4 pb-12"></div><div class="jsx-19ede9f0a5a45918 py-4 relative bg-primary md:px-8 -ml-6 xs:ml-0 w-screen xs:w-auto"><div class="jsx-19ede9f0a5a45918 px-4 sm:px-0"><div class="flex justify-between items-center py-1 space-x-4 border-0 select-none sm:border-b border-secondary"><div class="text-3xl text-white text-lg sm:text-3xl">Related Videos</div></div></div><div style="scroll-snap-type:none" class="jsx-19ede9f0a5a45918 flex items-start overflow-x-auto space-x-4 py-4 relative mx-auto w-full pl-4"><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" 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loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-white"></div></a></div></div><div class="relative block sm:hidden"><div class="mt-4 overflow-hidden"><div class="flex justify-between"><div class="flex items-center clear-both pt-4 pb-2 text-3xl lg:text-2xl xl:text-3xl min-w-fit ">Related Content </div><div class="hidden lg:flex w-full flex-col justify-end items-end"><div class="hidden w-full lg:flex flex-wrap pb-2 gap-x-2 gap-y-1 justify-end items-end"></div></div></div><div class="w-full mb-2 border border-secondary"></div><div class="lg:hidden flex flex-wrap items-center"></div><div class="flex flex-wrap w-full"><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-1"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/health-equity-access-weekly-roundup-november-23-2024?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/1fb0458d4007f177c86e1a37a8c9d4ba60b1f084-303x160.jpg?fit=crop&auto=format" alt="Center on Health Equity and Access" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 23rd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/health-equity-access-weekly-roundup-november-23-2024?utm_source=www.ajmc.com&utm_medium=relatedContent">Health Equity & Access Weekly Roundup: November 23, 2024</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/giuliana-grossi">Giuliana Grossi</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/health-equity-access-weekly-roundup-november-23-2024?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Americans are underinsured, even with employer-based health plans; a thorough critique of the lack of representation among Black patients in clinical trials showcases a persistent theme; systemic barriers in cardiology, breast cancer, and patent systems are examined.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/frameworks-for-advancing-health-equity-wellness-way?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/a1728e6a06fccde8af20d2308f860344f9776b8f-800x400.jpg?fit=crop&auto=format" alt="Managed Care Cast" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 21st 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/frameworks-for-advancing-health-equity-wellness-way?utm_source=www.ajmc.com&utm_medium=relatedContent">Frameworks for Advancing Health Equity: Wellness Way</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/giuliana-grossi">Giuliana Grossi</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/frameworks-for-advancing-health-equity-wellness-way?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The Wellness Way facility was designed to improve access to comprehensive outpatient care and address social determinants of health for a diverse patient population.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/5-things-you-should-know-about-long-covid?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/927c76dfea978e131974955e60f9f2f29ca1a840-5472x3100.jpg?fit=crop&auto=format" alt="Long COVID impact concept. | Image credit: Anucha - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 22nd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/5-things-you-should-know-about-long-covid?utm_source=www.ajmc.com&utm_medium=relatedContent">5 Things You Should Know About Long COVID</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/5-things-you-should-know-about-long-covid?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">In the current landscape of vaccine skepticism and misinformation, it is important to understand the full impact of long COVID on quality of life, especially among vulnerable populations. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/breaking-the-cycle-the-importance-of-early-intervention-in-hidradenitis-suppurativa?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/4d74ae04b0508977864936ec08f2aaa199758e5c-1000x563.jpg?fit=crop&auto=format" alt="Managed Care Cast" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 29th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/breaking-the-cycle-the-importance-of-early-intervention-in-hidradenitis-suppurativa?utm_source=www.ajmc.com&utm_medium=relatedContent">Breaking the Cycle: The Importance of Early Intervention in Hidradenitis Suppurativa</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/giuliana-grossi">Giuliana Grossi</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/breaking-the-cycle-the-importance-of-early-intervention-in-hidradenitis-suppurativa?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Prompt care supports mental well-being, as hidradenitis suppurativa is often associated with depression and anxiety due to its physical and social challenges.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/balancing-life-and-myeloma-a-patient-centered-approach?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/6c4eacfe9c992d1f7ea48bbb7606ade7b9a0b9cf-1920x1080.jpg?fit=crop&auto=format" alt="Don M. Benson, MD, PhD, James Cancer Hospital" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 22nd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/balancing-life-and-myeloma-a-patient-centered-approach?utm_source=www.ajmc.com&utm_medium=relatedContent">Balancing Life and Myeloma: A Patient-Centered Approach</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/maggie-l-shaw">Maggie L. Shaw</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/balancing-life-and-myeloma-a-patient-centered-approach?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">In this second part of our discussion with Don M. Benson, MD, PhD, from our recent Institute for Value-Based Medicine® event in Cleveland, Ohio, he explains how his ultimate goal for his patients is for them to live as long and as well as possible.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/semaglutide-eligibility-expands-to-over-half-of-us-adults?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/76c68f1b272ff40db499b3c5e4d48a6bb9da308d-5000x4000.jpg?fit=crop&auto=format" alt="Semaglutide injectors. | Image Credit :Andreas Prott- stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 21st 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/semaglutide-eligibility-expands-to-over-half-of-us-adults?utm_source=www.ajmc.com&utm_medium=relatedContent">Semaglutide Eligibility Expands to Over Half of US Adults</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/cameron-santoro">Cameron Santoro</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/semaglutide-eligibility-expands-to-over-half-of-us-adults?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Over half of the US adult population may benefit from semaglutide, a drug primarily used for weight loss and diabetes, although concerns about access and cost persist, especially considering its potential for wider health applications.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div></div></div></div><div class="relative hidden sm:block"><div class="mt-4 overflow-hidden"><div class="flex justify-between"><div class="flex items-center clear-both pt-4 pb-2 text-3xl lg:text-2xl xl:text-3xl min-w-fit ">Related Content </div><div class="hidden lg:flex w-full flex-col justify-end items-end"><div class="hidden w-full lg:flex flex-wrap pb-2 gap-x-2 gap-y-1 justify-end items-end"></div></div></div><div class="w-full mb-2 border border-secondary"></div><div class="lg:hidden flex flex-wrap items-center"></div><div class="flex flex-wrap w-full"><div class="jsx-ad50481d5ee26850 w-full h-full"><div><div><div class="text-[8px] text-center text-gray-500 hidden">Advertisement</div><div id="div-gpt-ad-infeed-1"></div></div></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/health-equity-access-weekly-roundup-november-23-2024?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/1fb0458d4007f177c86e1a37a8c9d4ba60b1f084-303x160.jpg?fit=crop&auto=format" alt="Center on Health Equity and Access" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 23rd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/health-equity-access-weekly-roundup-november-23-2024?utm_source=www.ajmc.com&utm_medium=relatedContent">Health Equity & Access Weekly Roundup: November 23, 2024</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/giuliana-grossi">Giuliana Grossi</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/health-equity-access-weekly-roundup-november-23-2024?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Americans are underinsured, even with employer-based health plans; a thorough critique of the lack of representation among Black patients in clinical trials showcases a persistent theme; systemic barriers in cardiology, breast cancer, and patent systems are examined.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/frameworks-for-advancing-health-equity-wellness-way?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/a1728e6a06fccde8af20d2308f860344f9776b8f-800x400.jpg?fit=crop&auto=format" alt="Managed Care Cast" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 21st 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/frameworks-for-advancing-health-equity-wellness-way?utm_source=www.ajmc.com&utm_medium=relatedContent">Frameworks for Advancing Health Equity: Wellness Way</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/giuliana-grossi">Giuliana Grossi</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/frameworks-for-advancing-health-equity-wellness-way?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">The Wellness Way facility was designed to improve access to comprehensive outpatient care and address social determinants of health for a diverse patient population.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex md:hidden justify-center items-center"></div><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/5-things-you-should-know-about-long-covid?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/927c76dfea978e131974955e60f9f2f29ca1a840-5472x3100.jpg?fit=crop&auto=format" alt="Long COVID impact concept. | Image credit: Anucha - stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 22nd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/5-things-you-should-know-about-long-covid?utm_source=www.ajmc.com&utm_medium=relatedContent">5 Things You Should Know About Long COVID</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/pearl-steinzor">Pearl Steinzor</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/5-things-you-should-know-about-long-covid?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">In the current landscape of vaccine skepticism and misinformation, it is important to understand the full impact of long COVID on quality of life, especially among vulnerable populations. </div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/breaking-the-cycle-the-importance-of-early-intervention-in-hidradenitis-suppurativa?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/4d74ae04b0508977864936ec08f2aaa199758e5c-1000x563.jpg?fit=crop&auto=format" alt="Managed Care Cast" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">October 29th 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/breaking-the-cycle-the-importance-of-early-intervention-in-hidradenitis-suppurativa?utm_source=www.ajmc.com&utm_medium=relatedContent">Breaking the Cycle: The Importance of Early Intervention in Hidradenitis Suppurativa</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/giuliana-grossi">Giuliana Grossi</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/breaking-the-cycle-the-importance-of-early-intervention-in-hidradenitis-suppurativa?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Prompt care supports mental well-being, as hidradenitis suppurativa is often associated with depression and anxiety due to its physical and social challenges.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/balancing-life-and-myeloma-a-patient-centered-approach?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/6c4eacfe9c992d1f7ea48bbb7606ade7b9a0b9cf-1920x1080.jpg?fit=crop&auto=format" alt="Don M. Benson, MD, PhD, James Cancer Hospital" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 22nd 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/balancing-life-and-myeloma-a-patient-centered-approach?utm_source=www.ajmc.com&utm_medium=relatedContent">Balancing Life and Myeloma: A Patient-Centered Approach</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/maggie-l-shaw">Maggie L. Shaw</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/balancing-life-and-myeloma-a-patient-centered-approach?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">In this second part of our discussion with Don M. Benson, MD, PhD, from our recent Institute for Value-Based Medicine® event in Cleveland, Ohio, he explains how his ultimate goal for his patients is for them to live as long and as well as possible.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div><div class="jsx-ad50481d5ee26850 w-full h-full"><div class="jsx-ad50481d5ee26850 flex flex-col sm:flex-row justify-between my-4 "><a class="jsx-ad50481d5ee26850" href="/view/semaglutide-eligibility-expands-to-over-half-of-us-adults?utm_source=www.ajmc.com&utm_medium=relatedContent"><img src="https://cdn.sanity.io/images/0vv8moc6/ajmc/76c68f1b272ff40db499b3c5e4d48a6bb9da308d-5000x4000.jpg?fit=crop&auto=format" alt="Semaglutide injectors. | Image Credit :Andreas Prott- stock.adobe.com" width="288" class="jsx-ad50481d5ee26850 max-h-[200px] xs:w-[288px] "/></a><div class="jsx-ad50481d5ee26850 article-detail flex flex-col gap-[0.2rem] w-full sm:w-[46%] md:w-[65%]"><span class="jsx-ad50481d5ee26850 article-publish-date block italic text-sm text-gray-500 mt-[1rem] sm:mt-0">November 21st 2024</span><p class="jsx-ad50481d5ee26850 article-title font-bold text-[1rem]"><a class="jsx-ad50481d5ee26850" href="/view/semaglutide-eligibility-expands-to-over-half-of-us-adults?utm_source=www.ajmc.com&utm_medium=relatedContent">Semaglutide Eligibility Expands to Over Half of US Adults</a></p><div class="jsx-ad50481d5ee26850 authors flex-row wrap gap-[0.2rem]"><a class="jsx-ad50481d5ee26850 text-[#00ADEF] underline text-sm italic" href="/authors/cameron-santoro">Cameron Santoro</a></div><div class="jsx-ad50481d5ee26850 article-summary"><a class="jsx-ad50481d5ee26850" href="/view/semaglutide-eligibility-expands-to-over-half-of-us-adults?utm_source=www.ajmc.com&utm_medium=relatedContent"><div class="jsx-ad50481d5ee26850 text-sm text-gray-500 py-1">Over half of the US adult population may benefit from semaglutide, a drug primarily used for weight loss and diabetes, although concerns about access and cost persist, especially considering its potential for wider health applications.</div></a></div></div></div><div style="border-bottom:1px solid #CCCCCC" class="jsx-ad50481d5ee26850"></div></div></div></div></div><div class="pb-24"></div></div><script type="application/ld+json">{"@context":"https://schema.org","@type":"NewsArticle","headline":"Edentulism May Heighten Sleep Apnea Risk","datePublished":"2024-11-23T15:00:00.000Z","dateModified":"2024-11-22T14:58:45Z","inLanguage":"en-US","image":"https://cdn.sanity.io/images/0vv8moc6/ajmc/d8405a2a194a2c5f871d2c521ca31d0ec29d29bc-1200x738.jpg?fit=crop&auto=format","mainEntityOfPage":{"@type":"WebPage","@id":"https://www.ajmc.com/view/edentulism-may-heighten-sleep-apnea-risk"},"publisher":{"@type":"Organization","name":"AJMC","logo":{"@type":"ImageObject","url":"https://www.ajmc.com/ajmc_logo_inverted.png"}},"keywords":"sleep,Edentulism ,sleep apnea,sleep apnea risk","articleBody":"\n\nAnatomical alterations associated with tooth loss, also known as edentulism, appear to increase the risk of obstructive sleep apnea (OSA), according to a new systematic review.1The report, which was published in Journal of Prosthodontics, found unanimous agreement on the link, although the impact of remedies such as dentures remains unclear.\n\n\n\nLeft untreated, and often undiagnosed, OSA can lead to several concerning comorbidities, including hypertension, diabetes, and impaired cognitive function, noted the study authors. A study published in 2022 found that the high rate of undiagnosed OSA is tied to a lack of coordination of care, negative perceptions about the disease, and a belief among patients that their OSA symptoms are not serious enough to warrant medical care.2\n\n\n\nThe authors noted that although most sleep-related disorders are treated by medical doctors, some sleep issues can be related to the dental field.\n\n\n\n“Oral care may be influenced by OSA and there have already been studies concerning the association of OSA with increased prevalence of periodontal disease, as well as with tooth wear, orofacial pain, and xerostomia,” they wrote.\n\n\n\n\n\nThe link between edentulism and OSA has been studied for a number of years, in part because complete tooth loss has already been associated with diseases including periodontitis, oral cancer, and trauma, they noted. Moreover, the loss of teeth can spark anatomical changes affecting the size and function of the upper airway.\n\n\n\n“Changes that are also frequently observed include loss of the vertical dimension of occlusion, mandibular rotation, and reduction of the lower face height,” they wrote. “Increased collapsibility of the pharynx can act as a causal factor for OSA.”\n\n\n\nThey wanted to better understand what the existing scientific literature says about links between OSA and edentulism, and see what conclusions—if any—could be drawn, so they searched a number of scientific databases for relevant studies investigating potential links between OSA and edentulism. They found 23 such studies, published between from 1999 to 2023, all of which were clinical studies and 6 of which were randomized controlled trials.\n\n\n\nThe studies were unanimous in concluding that there is an association between edentulism and OSA, the authors found. They suggest that Apnea-Hypopnea Index scores were 2 to 3 times higher in people with edentulism than people with teeth. However, the authors cautioned that there were relatively few data directly comparing edentulous and dentate patients, which they said indicates a need for more research into the question. They also said differences in study methods, OSA diagnostic tools, and outcome criteria made it impossible to do a meta-analysis.\n\n\n\nAnother question that has been evaluated is the impact of dentures on OSA risk. The existing research is inconclusive, they noted, with some studies suggesting that dentures can increase the risk of OSA and other studies finding that dentures decrease the risk. A more recent study that looked specifically at implant-supported mandibular dentures, however, found they can improve airway space and symptoms in people with mild to moderate OSA.3\n\n\n\nThe authors said the data show a “plausible” association between edentulism and OSA, which they said underscores the importance of prosthodontic management and the prevention of tooth loss.\n\n\n\n“However, clinical data are limited and heterogenous, so more clinical studies should be encouraged for more robust conclusions,” they wrote.\n\n\n\nReferences\n\n1. Pachiou A, Roulias P, Steiropoulos P, Halazonetis DJ, Kourtis S. Association of edentulism and obstructive sleep apnea: a systematic review. J Prosthodont. Published online November 13, 2024. doi:10.1111/jopr.13981\n\n2. Ye L, Li W, Willis DG. Facilitators and barriers to getting obstructive sleep apnea diagnosed: perspectives from patients and their partners. J Clin Sleep Med. 2022;18(3):835-841. doi:10.5664/jcsm.9738\n\n3. Krishnamurthy P, Maheswari U, Mohamed K. Effect of prosthetic rehabilitation on airway space in edentulous patients with obstructive sleep apnea- a preliminary observational study. J Dent (Shiraz). 2023;24(4):382-388. doi:10.30476/dentjods.2022.95716.1886\n\n","description":"A systematic review has found a potential link between edentulism and sleep apnea risk, although the authors said differences in study designs prohibited a meta-analysis.","author":[{"@type":"Person","name":"Jared Kaltwasser"}]}</script></div></div><div class="flex-none w-[300px] z-[9999] relative hidden md:block"><div style="top:5rem" class="sticky custom-spacing"><div class="collapse-container " style="overflow:hidden;max-height:900px;transition:max-height .4s ease-in-out"></div></div></div></div><div id="div-gpt-ad-pixel" style="width:1px;height:1px" class=""></div><noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-NK5KQXS" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript><div id="footerOuterWrap" class=" mx-auto flex"><div class="bg-[#00598D] xl:w-[70%] w-[70%] py-12 pl-auto"><div class="xxl:w-[75%] w-[90%] ml-auto"><div><span 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Moreover, the loss of teeth can spark anatomical changes affecting the size and function of the upper airway.","_key":"aefd8b1a9f610"}]},{"children":[{"_type":"span","marks":[],"text":"","_key":"539a9cd6f1550"}],"upload_doc":null,"uploadAudio":null,"medias":null,"_type":"block","style":"normal","_key":"ff1adb42426d","markDefs":[]},{"children":[{"_type":"span","marks":[],"text":"“Changes that are also frequently observed include loss of the vertical dimension of occlusion, mandibular rotation, and reduction of the lower face height,” they wrote. “Increased collapsibility of the pharynx can act as a causal factor for OSA.”","_key":"4d17b4fe5fcd0"}],"_type":"block","upload_doc":null,"uploadAudio":null,"medias":null,"style":"normal","_key":"d0c3f5637115","markDefs":[]},{"children":[{"_type":"span","marks":[],"text":"","_key":"082349298fc00"}],"_type":"block","style":"normal","_key":"5e9fc41d7b1c","markDefs":[],"upload_doc":null,"uploadAudio":null,"medias":null},{"upload_doc":null,"uploadAudio":null,"medias":null,"markDefs":[],"children":[{"_type":"span","marks":[],"text":"They wanted to better understand what the existing scientific literature says about links between OSA and edentulism, and see what conclusions—if any—could be drawn, so they searched a number of scientific databases for relevant studies investigating potential links between OSA and edentulism. They found 23 such studies, published between from 1999 to 2023, all of which were clinical studies and 6 of which were randomized controlled trials.","_key":"ec4726a420040"}],"_type":"block","style":"normal","_key":"705b5175718f"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"e834297069ac0"}],"_type":"block","style":"normal","_key":"ea63d03014e5","upload_doc":null,"uploadAudio":null,"medias":null},{"upload_doc":null,"uploadAudio":null,"medias":null,"_type":"block","style":"normal","_key":"c5c180d5f2e5","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The studies were unanimous in concluding that there is an association between edentulism and OSA, the authors found. They suggest that Apnea-Hypopnea Index scores were 2 to 3 times higher in people with edentulism than people with teeth. However, the authors cautioned that there were relatively few data directly comparing edentulous and dentate patients, which they said indicates a need for more research into the question. They also said differences in study methods, OSA diagnostic tools, and outcome criteria made it impossible to do a meta-analysis.","_key":"1f0847d503150"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"d19cb9a41d950"}],"_type":"block","style":"normal","upload_doc":null,"uploadAudio":null,"medias":null,"_key":"f7531c4f1f7b"},{"children":[{"_key":"abec7bf6b6970","_type":"span","marks":[],"text":"Another question that has been evaluated is the impact of dentures on OSA risk. The existing research is inconclusive, they noted, with some studies suggesting that dentures can increase the risk of OSA and other studies finding that dentures decrease the risk. A "},{"marks":["35f2bb436b66"],"text":"more recent study","_key":"abec7bf6b6971","_type":"span"},{"_type":"span","marks":[],"text":" that looked specifically at implant-supported mandibular dentures, however, found they can improve airway space and symptoms in people with mild to moderate OSA.","_key":"abec7bf6b6972"},{"text":"3","_key":"ebc2975378e6","_type":"span","marks":["superscript"]}],"_type":"block","style":"normal","_key":"602bdf3a65bd","upload_doc":null,"uploadAudio":null,"medias":null,"markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://dentjods.sums.ac.ir/article_48879.html","_key":"35f2bb436b66"}]},{"style":"normal","_key":"04cb188be8e6","upload_doc":null,"uploadAudio":null,"medias":null,"markDefs":[],"children":[{"marks":[],"text":"","_key":"e293351702310","_type":"span"}],"_type":"block"},{"upload_doc":null,"uploadAudio":null,"medias":null,"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The authors said the data show a “plausible” association between edentulism and OSA, which they said underscores the importance of prosthodontic management and the prevention of tooth loss.","_key":"70e7e788832b0"}],"_type":"block","style":"normal","_key":"4066ffa1fb1b"},{"medias":null,"markDefs":[],"children":[{"marks":[],"text":"","_key":"65c9689ec36e0","_type":"span"}],"_type":"block","style":"normal","_key":"73dfa0ac768e","upload_doc":null,"uploadAudio":null},{"medias":null,"_type":"block","style":"normal","_key":"afd2f29abf1f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“However, clinical data are limited and heterogenous, so more clinical studies should be encouraged for more robust conclusions,” they wrote.","_key":"8dc157f6bf5a0"}],"upload_doc":null,"uploadAudio":null},{"uploadAudio":null,"medias":null,"markDefs":[],"children":[{"text":"","_key":"2c0e07b996950","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"77ca49258627","upload_doc":null},{"children":[{"_key":"e90434645a9d0","_type":"span","marks":["strong"],"text":"References"}],"_type":"block","upload_doc":null,"uploadAudio":null,"medias":null,"style":"normal","_key":"e974d605f021","markDefs":[]},{"_type":"block","style":"normal","upload_doc":null,"uploadAudio":null,"medias":null,"_key":"b5b6f290f58e","markDefs":[],"children":[{"_type":"span","marks":[],"text":"1. Pachiou A, Roulias P, Steiropoulos P, Halazonetis DJ, Kourtis S. Association of edentulism and obstructive sleep apnea: a systematic review. ","_key":"e30ad513e5250"},{"text":"J Prosthodont","_key":"e30ad513e5251","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":". Published online November 13, 2024. doi:10.1111/jopr.13981","_key":"e30ad513e5252"}]},{"children":[{"_type":"span","marks":[],"text":"2. Ye L, Li W, Willis DG. Facilitators and barriers to getting obstructive sleep apnea diagnosed: perspectives from patients and their partners. ","_key":"551a72c715b20"},{"text":"J Clin Sleep Med","_key":"551a72c715b21","_type":"span","marks":["em"]},{"text":". 2022;18(3):835-841. doi:10.5664/jcsm.9738","_key":"551a72c715b22","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"ddfa4413b9a6","upload_doc":null,"uploadAudio":null,"medias":null,"markDefs":[]},{"children":[{"text":"3. Krishnamurthy P, Maheswari U, Mohamed K. Effect of prosthetic rehabilitation on airway space in edentulous patients with obstructive sleep apnea- a preliminary observational study. ","_key":"39685a5c77cd0","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"J Dent (Shiraz)","_key":"39685a5c77cd1"},{"_type":"span","marks":[],"text":". 2023;24(4):382-388. doi:10.30476/dentjods.2022.95716.1886","_key":"39685a5c77cd2"}],"_type":"block","style":"normal","_key":"81bb9c8d0104","upload_doc":null,"uploadAudio":null,"medias":null,"markDefs":[]},{"style":"normal","_key":"a2eab0b1ce27","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"6560e444aa6f0"}],"upload_doc":null,"uploadAudio":null,"medias":null,"_type":"block"}],"documentGroup":null,"factCheckAuthorMapping":null,"summary":"A systematic review has found a potential link between edentulism and sleep apnea risk, although the authors said differences in study designs prohibited a meta-analysis.","thumbnail":{"alt":"Tooth loss | Image Credit: © valiantsin-stock.adobe.com","asset":{"_ref":"image-d8405a2a194a2c5f871d2c521ca31d0ec29d29bc-1200x738-jpg","_type":"reference"},"_type":"mainImage"},"taxonomyMapping":[{"identifier":"sleep","name":"Sleep","perKeywordMapping":["Neurology","Pulmonology","Health Equity Diversity \u0026 Inclusion"],"_createdAt":"2020-04-14T15:02:13Z","_rev":"rs7eCk0lrr8LMiZP9GCG8D","pixelTrackingCode":null,"parent":{"_type":"taxonomy","_id":"297fa3d1-5216-46eb-bf51-66c5f77c3c8a","_updatedAt":"2024-04-09T09:14:18Z","identifier":"compendium","_createdAt":"2020-03-30T18:16:46Z","_rev":"oruil6rlosjyltJbhrNMGF","name":"Compendium","isMainTopic":true,"parent":null},"_updatedAt":"2023-11-03T18:16:19Z","cmeType":"per","_type":"taxonomy","_id":"compendium_sleep"},{"_rev":"OU32WOWh4YetHW0RkWbkso","_updatedAt":"2022-01-19T10:20:16Z","parent":null,"_type":"taxonomy","name":"News","_id":"39be7351-bd4c-4e98-82b3-0d675ae4671b","identifier":"news","_createdAt":"2020-03-30T18:05:45Z","pixelTrackingCode":null},{"identifier":"healthcare-delivery","parent":{"_type":"taxonomy","name":"Topic","_updatedAt":"2021-10-21T10:15:35Z","isMainTopic":true,"_rev":"SpZIJtjiAn4ebHE4u6sWYc","_id":"15012229-f713-4f0a-8f82-7667530bb382","identifier":"topic","parent":null,"_createdAt":"2020-03-31T14:24:50Z"},"_createdAt":"2020-05-04T23:46:13Z","_rev":"52vAUxG62nnEnK65ZDo5dG","_type":"taxonomy","name":"Health Care Delivery","_id":"topic_healthcare-delivery","pixelTrackingCode":null,"_updatedAt":"2022-11-29T18:34:57Z"}],"contentCategory":{"_id":"3f4b3ced-7c9d-4fc4-967f-fe993087cce2","name":"Articles"},"audioUrl":"https://s3.us-east-1.amazonaws.com/ai-generated-audios/www.ajmc.com/809dec58-4f3c-49a1-8c2b-53878dc5e0c3_1732287524998.d7ccfc98-396b-4973-91dc-9cb086ab576f.mp3","gptSummary":"A systematic review highlights a potential link between edentulism and obstructive sleep apnea (OSA), suggesting anatomical changes from tooth loss may increase OSA risk. 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Leaving the complexities aside for a second, the principal goal of induction treatment is to alleviate suffering, get symptoms under control, get the disease in remission. I tell my patients, we're going to play offense, we're going to take the ball. We're playing offense, and the goal is a complete remission. The goal is to get you back to life before you heard those words that you have myeloma.","_key":"98a12fa87f160"}]},{"_type":"block","style":"normal","_key":"b87ccab950ce","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"e5122cc087dd0"}]},{"_type":"block","style":"normal","_key":"4fa1f2e9a11a","markDefs":[],"children":[{"_type":"span","marks":[],"text":"We’re blessed. We can achieve that now for the vast majority of people within a few months.The challenge really isn't getting the disease under control nowadays, it's doing it in a way to minimize toxicities, minimize side effects, even down to things like time. How long are you in the clinic? How long are you away from your life? These are things that we never would have thought of 20 years ago. So I think starting with principles and then moving forward, once the disease is in remission.","_key":"903297a2544e0"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"d68b2f25f9270"}],"_type":"block","style":"normal","_key":"350f7d4b1a54"},{"_type":"block","style":"normal","_key":"0e3a9819924f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"We talk a little bit about this shared decision-making model of, we have a panoply of options available. What makes sense for you with your myeloma right now? Realizing that that answer might be different 2 years from now or 5 years from now. But what can we do right now to stay on our true north, that I want you to live as long as possible and as well as possible. And for some people, that's a transplant.For some people, that's maybe a CAR [chimeric antigen receptor] T cell. For some people, that might be stopping treatment and just taking a maintenance drug.","_key":"6f14e254c8760"}]},{"style":"normal","_key":"db2656198b38","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"cb0db495ec3c0"}],"_type":"block"},{"_type":"block","style":"normal","_key":"6d35a1abcd26","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"What strategies can be implemented to support caregivers and enhance patient engagement throughout this journey?","_key":"e44a4e9608260"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"1dce3cf224050"}],"_type":"block","style":"normal","_key":"6c3f5f7fe4dd"},{"_key":"9a1ed96927d7","markDefs":[],"children":[{"_type":"span","marks":[],"text":"I can speak to my perspective at a referral center that the vast majority of people with myeloma are receiving care in community settings. Oftentimes, when we get involved at a referral center, at an academic center, there's potentially a question about transplant eligibility, about eligibility for a BiTE [bispecific T-cell engager] or a CAR T cell. But just as often, these are referrals that are like grassroots referrals, and it's often an adult child who's driving care.It's not the patient who's maybe 75 or 80 years old, it's an adult child who's gotten on the internet, who's going to support groups, who's done his or her homework, and is saying, “Mom, I really think it's worth the drive to this center. Not that we are unhappy with our care, not that we disagree with our care, but this is a rare cancer. Maybe it would make sense to have somebody look at your case and meet you once, who does it for a living, who sees it every day.”","_key":"1350599e72c50"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"c81bbcef117c","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"87957829728e0"}]},{"style":"normal","_key":"4194d4d05490","markDefs":[],"children":[{"_key":"9f0e0feae61c0","_type":"span","marks":[],"text":"And I'm all about that. I think that's so important. Myeloma is a rare cancer, and I think the more that—the patient, obviously—but the patient's family, their loved ones, and most often it's the adult children—it's actually usually the oldest daughter for what it's worth, who's taking time off work, who's finding childcare, who's making sacrifices to make sure mom or dad is getting the best care possible. 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The mean age of participants was 50.7 years, and there were slightly fewer women than men (49.1%).","_key":"82c98c44c3910"}],"_type":"block","style":"normal","_key":"9528eb07c39d"},{"style":"normal","_key":"3dd71c9661d0","markDefs":[],"children":[{"_key":"479c668371230","_type":"span","marks":[],"text":""}],"_type":"block"},{"children":[{"_key":"3657e27c32db0","_type":"span","marks":[],"text":"Insurance coverage of the predicted semaglutide-eligible population included 26.8 million insured by Medicare, 13.8 million insured by Medicaid, and 61.1 million covered by private insurance. By indication, 35 million US adults would be eligible for semaglutide for diabetes management, 129.2 million for weight management, and 8.9 million for secondary prevention of cardiovascular disease."}],"_type":"block","style":"normal","_key":"12f77c8bb178","markDefs":[]},{"markDefs":[],"children":[{"text":"","_key":"3205e67fcd800","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"4b05b156adae"},{"style":"normal","_key":"1bde3c7c0b14","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Of the 39.3 million US adults eligible for semaglutide for diabetes or secondary prevention of cardiovascular disease, 13 million are insured by Medicare and 4.7 million insured by Medicaid. 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However, the large proportion of US adults who qualify for semaglutide emphasizes the possible impact of broader uptake on pharmaceutical spending and population health."}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"c5eb8ab7a397"}],"_type":"block","style":"normal","_key":"72606de98e4a"},{"style":"normal","_key":"e5b5a4bec1de","markDefs":[],"children":[{"_key":"c33cbe12e67e0","_type":"span","marks":[],"text":"Other individuals who reported using semaglutide medications stated that the therapy was difficult to afford,"},{"text":"3","_key":"9981dd9c85fa","_type":"span","marks":["superscript"]},{"_type":"span","marks":[],"text":" so interventions that reduce economic barriers to access that are urgently needed, especially with obesity’s prevalence projected to dramatically increase to 250 million Americans by 2050.","_key":"9feee62503de"},{"_type":"span","marks":["superscript"],"text":"4","_key":"128d96622212"}],"_type":"block"},{"_type":"block","style":"normal","_key":"e1f4b4fa0d97","markDefs":[],"children":[{"_key":"b66b671871de0","_type":"span","marks":[],"text":""}]},{"_type":"block","style":"normal","_key":"a450be41ad90","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“Efforts to increase equitable uptake should be coupled with strategies to ensure that the cost of semaglutide is commensurate with the value of the health benefits it produces,” concluded the study authors.","_key":"905b4056bbe50"},{"_key":"b2955d48aa1b","_type":"span","marks":["superscript"],"text":"1"}]},{"markDefs":[],"children":[{"marks":[],"text":"","_key":"e1c255a45a6f0","_type":"span"}],"_type":"block","style":"normal","_key":"2ba1b81e7fec"},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"References","_key":"2674e0e5e5000"}],"_type":"block","style":"normal","_key":"68187c2238a4"},{"_key":"98821506fe59","markDefs":[],"children":[{"_type":"span","marks":[],"text":"1. 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