Nature Synthesis

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<source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs44160-024-00681-8/MediaObjects/44160_2024_681_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00681-8/MediaObjects/44160_2024_681_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00681-8/MediaObjects/44160_2024_681_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00681-8" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Mechano-photoexcitation for organic synthesis using mechanoluminescent materials as photon sources</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>The combination of mechanochemical and photochemical approaches is often hindered by the limited transparency of reaction vessels. Now, a mechano-photoexcitation strategy is reported using mechanoluminescent materials as internal photon sources activated by mechanical energy. This approach enables solvent-free photochemical reactions, as demonstrated in Hofmann–Löffler–Freytag and sulfonylation reactions.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Xiaohua Xin</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jinxing Geng</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Han Wang</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-14" itemprop="datePublished">14 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs44160-024-00678-3/MediaObjects/44160_2024_678_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00678-3/MediaObjects/44160_2024_678_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00678-3/MediaObjects/44160_2024_678_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00678-3" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Diffusion-mediated synthesis of high-quality organic–inorganic hybrid perovskite nanocrystals</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>A diffusion-mediated synthesis strategy for organic–inorganic hybrid perovskite nanocrystals is reported, which can substantially slow down the reaction kinetics, improving size uniformity and achieving near-unity photoluminescence quantum yield.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Xiang Sun</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Lin Yuan</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Wanli Ma</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-14" itemprop="datePublished">14 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs44160-024-00672-9/MediaObjects/44160_2024_672_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00672-9/MediaObjects/44160_2024_672_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00672-9/MediaObjects/44160_2024_672_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00672-9" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Carbonate shell regulates CuO surface reconstruction for enhanced CO<sub>2</sub> electroreduction</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Electrochemical reconstruction impacts the surface structure of electrocatalysts and is challenging to control in CO<sub>2</sub> electroreduction. Here, by regulating a carbonate shell around an oxide catalyst, the reconstruction is guided towards an abundant low-coordinated structure, achieving a C<sub>2+</sub> Faradaic efficiency of 82.8 ± 2.2% at a current density of 2 A cm<sup>−2</sup>.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Xianhui Ma</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Tong Yang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Yuen Wu</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-10-31" itemprop="datePublished">31 Oct 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs44160-024-00671-w/MediaObjects/44160_2024_671_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00671-w/MediaObjects/44160_2024_671_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00671-w/MediaObjects/44160_2024_671_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00671-w" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">An engineered aldolase enables the biocatalytic synthesis of 2′-functionalized nucleoside analogues</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>The chemical synthesis of nucleoside analogues with modifications at the 2-position often requires multiple steps and the extensive use of protecting groups. Now, biocatalytic cascades are reported for the synthesis of 2-functionalized sugars and 2′-functionalized nucleosides, using enzymes derived from those of the purine nucleoside salvage pathway.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Matthew Willmott</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">William Finnigan</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Nicholas J. Turner</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><span class="c-meta__item c-meta__item--block-at-lg" itemprop="openAccess" data-test="open-access"><span class="u-color-open-access">Open Access</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-05" itemprop="datePublished">05 Nov 2024</time> </div> </article> </div> </li> </ul> </div> </section> <section id="latest-issue" data-track-component="latest-issue grid"> <div class="u-container u-mb-48"> <div class="c-section-heading"> <h2 class="u-ma-0"> <a href="/natsynth/current-issue" class="c-section-heading__link" data-track="click" data-track-action="view all" data-track-label="button"> Current issue <svg class="c-section-heading__icon" aria-hidden="true" focusable="false" height="16" width="16"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-chevron-right"></use></svg> </a> </h2> </div> <div class="app-latest-issue-row"> <div class="app-latest-issue-row__main u-display-flex u-flex-direction-column u-flex-shrink"> <ul class="app-latest-issue-row__article-list"> <li class="app-latest-issue-row__item"><div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00684-5" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Electrochemical etherification and amination</a> </h3> <ul data-test="author-list" class="c-author-list c-author-list--compact"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Peter W. 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Canty</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Milad Abolhasani</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">Review Article</span></span><time class="c-meta__item" datetime="2024-10-10" itemprop="datePublished">10 Oct 2024</time> </div> </article> </div></li> <li class="app-latest-issue-row__item"><div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00596-4" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Biocatalytic desymmetrization for 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<div class="c-card__layout u-full-height"> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00605-6" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Iron-catalysed C(<i>sp</i>²)–H activation for aza-annulation with alkynes on extended <i>π</i>-conjugated systems</a> </h3> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Yan Zhang</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Shota Fukuma</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Eiichi Nakamura</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item" datetime="2024-07-09" itemprop="datePublished">09 Jul 2024</time> </div> </article> </div></li> </ul> </div> <div class="app-latest-issue-row__side"> <div class="app-latest-issue-row__image"> <picture> <source type="image/webp" srcset="https://media.springernature.com/w440/springer-static/cover-hires/journal/44160/3/11?as=webp&q=95"> <img src="https://media.springernature.com/w440/springer-static/cover-hires/journal/44160/3/11?q=95" alt="Volume 3 Issue 11" itemprop="image"> </picture> </div> <div class="app-latest-issue-row__buttons app-latest-issue-row--by-3"> <div class="app-latest-issue-row__button"> <a href="/natsynth/current-issue" class="u-button u-button--full-width" data-track="click" data-track-action="view current issue" data-track-label="button">Contents</a> </div> <div class="app-latest-issue-row__button"> <a href="/natsynth/volumes/3" class="u-button u-button--full-width" data-track="click" data-track-action="click view all issues">View all issues</a> </div> <div class="app-latest-issue-row__button"><a href="/natsynth/subscribe" class="u-button u-button--primary u-button--full-width" data-track="click" data-track-action="subscribe" data-track-label="button">Subscribe</a></div> </div> </div> </div> </div> </section> <section id="announcement-content" class="u-mb-48 u-mt-24" data-track-component="announcement content grid"> <div class="u-container"> <div class="c-section-heading" data-test="title"> <h2 class="u-ma-0"> Announcements </h2> </div> <ul class="app-announcement-list-row"> <li class="app-announcement-list-row__item"> <article class="c-card c-card--flush u-pl-0 u-justify-content-space-between"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/nature-cms/uploads/mosaic_featured_form_item/17128/announcement-image-8cf462f5aeebaf95c507244288bd8f64.jpg?as=webp 160w, https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/17128/announcement-image-8cf462f5aeebaf95c507244288bd8f64.jpg?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img data-test="image-0" src="https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/17128/announcement-image-8cf462f5aeebaf95c507244288bd8f64.jpg" alt="Reaction over cubic catalyst" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline" data-test="announcement-title-0"> <a href="https://www.nature.com/collections/dfigjddgdc/" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="click on homepage featured announcement" data-track-label="announcement 0"> Ammonia synthesis </a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description" data-test="description-0"> <p>Ammonia is an essential global chemical but its synthesis is energy intensive and pollutes the environment. This Focus issue highlights recent developments in green ammonia synthesis, as well as discussing the challenges which need to be overcome for the commercial production of green ammonia.</p> </div> </div> </div> </article> </li> <li class="app-announcement-list-row__item"> <article class="c-card c-card--flush u-pl-0 u-justify-content-space-between"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/nature-cms/uploads/mosaic_featured_form_item/17128/announcement-image-2e5ecd1e51b74bfe4f5bf9fada1654d0.jpg?as=webp 160w, https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/17128/announcement-image-2e5ecd1e51b74bfe4f5bf9fada1654d0.jpg?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img data-test="image-1" src="https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/17128/announcement-image-2e5ecd1e51b74bfe4f5bf9fada1654d0.jpg" alt="Robot arms working in chemistry laboratory." itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline" data-test="announcement-title-1"> <a href="https://www.nature.com/collections/ddbfdfhfbh" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="click on homepage featured announcement" data-track-label="announcement 1"> Data-driven automated synthesis </a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description" data-test="description-1"> <p>The combination of techniques such as machine learning, artificial intelligence, robotics and automation can be used to accelerate chemical and materials synthesis. This Focus issue showcases developments in the automation and digitalization of synthesis, as well as highlights the challenges to be overcome in this area.</p> </div> </div> </div> </article> </li> <li class="app-announcement-list-row__item"> <article class="c-card c-card--flush u-pl-0 u-justify-content-space-between"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/nature-cms/uploads/mosaic_featured_form_item/17128/announcement-image-35c6957af5ac38247c5e995638926280.jpg?as=webp 160w, https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/17128/announcement-image-35c6957af5ac38247c5e995638926280.jpg?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img data-test="image-2" src="https://media.springernature.com/w290h158/nature-cms/uploads/mosaic_featured_form_item/17128/announcement-image-35c6957af5ac38247c5e995638926280.jpg" alt="Pipes in chemical factory" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline" data-test="announcement-title-2"> <a href="https://www.nature.com/collections/aejihjeiba" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="click on homepage featured announcement" data-track-label="announcement 2"> Synthesis in flow </a> </h3> <div class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description" data-test="description-2"> <p>Flow chemistry is an enabling technology which is used to tackle synthetic problems in both industrial and academic settings. 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Now, a synthesis protocol that integrates mechanical and chemical effects achieves enhanced crystalline orientation and uniformity.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Hong Liu</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Haodong Wu</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Congcong Wu</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-22" itemprop="datePublished">22 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs44160-024-00679-2/MediaObjects/44160_2024_679_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00679-2/MediaObjects/44160_2024_679_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00679-2/MediaObjects/44160_2024_679_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00679-2" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Phase-switchable preparation of solution-processable WS<sub>2</sub> mono- or bilayers</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Phase-switchable preparation of two-dimensional WS<sub>2</sub> is achieved through an electrochemical Li<sup>+</sup> intercalation-based exfoliation strategy. A low discharge current density with high cutoff voltage produces pure semiconducting 2H phase WS<sub>2</sub> bilayers, while a higher discharge current density with a lower cutoff voltage favours semimetallic 1T′ phase WS<sub>2</sub> monolayers.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Liang Mei</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Zhan Gao</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Zhiyuan Zeng</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-15" itemprop="datePublished">15 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs44160-024-00681-8/MediaObjects/44160_2024_681_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00681-8/MediaObjects/44160_2024_681_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00681-8/MediaObjects/44160_2024_681_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00681-8" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Mechano-photoexcitation for organic synthesis using mechanoluminescent materials as photon sources</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>The combination of mechanochemical and photochemical approaches is often hindered by the limited transparency of reaction vessels. Now, a mechano-photoexcitation strategy is reported using mechanoluminescent materials as internal photon sources activated by mechanical energy. This approach enables solvent-free photochemical reactions, as demonstrated in Hofmann–Löffler–Freytag and sulfonylation reactions.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Xiaohua Xin</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jinxing Geng</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Han Wang</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-14" itemprop="datePublished">14 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs44160-024-00678-3/MediaObjects/44160_2024_678_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00678-3/MediaObjects/44160_2024_678_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00678-3/MediaObjects/44160_2024_678_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00678-3" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Diffusion-mediated synthesis of high-quality organic–inorganic hybrid perovskite nanocrystals</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>A diffusion-mediated synthesis strategy for organic–inorganic hybrid perovskite nanocrystals is reported, which can substantially slow down the reaction kinetics, improving size uniformity and achieving near-unity photoluminescence quantum yield.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Xiang Sun</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Lin Yuan</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Wanli Ma</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-14" itemprop="datePublished">14 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs44160-024-00677-4/MediaObjects/44160_2024_677_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00677-4/MediaObjects/44160_2024_677_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00677-4/MediaObjects/44160_2024_677_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00677-4" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">Analysis of siderochelin biosynthesis reveals that a type II polyketide synthase catalyses diketide formation</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>Type II polyketide synthases (PKSs) comprise multiple enzymes and control the biosynthesis of polyketides by using a malonyl extender unit for decarboxylative elongation. Now, genome mining, gene inactivation, isotopic labelling and biochemical analysis reveal that the biosynthetic pathway of siderochelin proceeds through a five-component type II PKS which uses a methylmalonyl extender for diketide formation.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Yao Qian</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Jinmin Gao</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Wen Liu</span></li> </ul> </div> </div> <div class="c-card__section c-meta"> <span class="c-meta__item c-meta__item--block-at-lg" data-test="article.type"><span class="c-meta__type">Article</span></span><time class="c-meta__item c-meta__item--block-at-lg" datetime="2024-11-06" itemprop="datePublished">06 Nov 2024</time> </div> </article> </div> </li> <li class="app-article-list-row__item"> <div class="u-full-height" data-native-ad-placement="false"> <article class="u-full-height c-card c-card--flush" itemscope itemtype="http://schema.org/ScholarlyArticle"> <div class="c-card__layout u-full-height"> <div class="c-card__image"> <picture> <source type="image/webp" srcset=" https://media.springernature.com/w165h90/springer-static/image/art%3A10.1038%2Fs44160-024-00671-w/MediaObjects/44160_2024_671_Figa_HTML.png?as=webp 160w, https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00671-w/MediaObjects/44160_2024_671_Figa_HTML.png?as=webp 290w" sizes=" (max-width: 640px) 160px, (max-width: 1200px) 290px, 290px"> <img src="https://media.springernature.com/w290h158/springer-static/image/art%3A10.1038%2Fs44160-024-00671-w/MediaObjects/44160_2024_671_Figa_HTML.png" alt="" itemprop="image"> </picture> </div> <div class="c-card__body u-display-flex u-flex-direction-column"> <h3 class="c-card__title" itemprop="name headline"> <a href="/articles/s44160-024-00671-w" class="c-card__link u-link-inherit" itemprop="url" data-track="click" data-track-action="view article" data-track-label="link">An engineered aldolase enables the biocatalytic synthesis of 2′-functionalized nucleoside analogues</a> </h3> <div data-test="article-description" class="c-card__summary u-mb-16 u-hide-sm-max" itemprop="description"> <p>The chemical synthesis of nucleoside analogues with modifications at the 2-position often requires multiple steps and the extensive use of protecting groups. Now, biocatalytic cascades are reported for the synthesis of 2-functionalized sugars and 2′-functionalized nucleosides, using enzymes derived from those of the purine nucleoside salvage pathway.</p> </div> <ul data-test="author-list" class="c-author-list c-author-list--compact c-author-list--truncated"> <li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Matthew Willmott</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">William Finnigan</span></li><li itemprop="creator" itemscope="" itemtype="http://schema.org/Person"><span itemprop="name">Nicholas J. 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