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2022 - Transfusionsmedizin | Uniklinikum Erlangen
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frame-container-default"><div class="frame-inner"><header class="frame-header"><h1 class="element-header mb-2"><span>2022</span></h1></header></div></div></div></div><nav class="breadcrumb-section" aria-label="Brotkrümelnavigation"><div class="container"><p class="sr-only" id="breadcrumb">Sie sind hier:</p><ol class="breadcrumb"><li class="breadcrumb-item"><a class="breadcrumb-link" href="https://www.uk-erlangen.de/" title="Zur Startseite des Universitätsklinikums Erlangen"><svg height="37" xmlns="http://www.w3.org/2000/svg" viewBox="0,0,63,64"><g><path d="M20.937+21.0438L0+21.0438L0+42.3789L20.937+42.3789L20.937+21.0438Z" opacity="1" fill="#00a579"/><path d="M62.813+21.0438L41.876+21.0438L41.876+42.3789L62.813+42.3789L62.813+21.0438Z" opacity="1" fill="#00a579"/><path d="M41.876+21.0438L20.938+21.0438L20.938+42.3789L41.876+42.3789L41.876+21.0438Z" opacity="1" fill="#2761ab"/><path d="M41.876+42.3788L20.938+42.3788L20.938+63.7138L41.876+63.7138L41.876+42.3788Z" opacity="1" 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class=" frame frame-default frame-type-text frame-layout-default frame-size-default frame-height-default frame-background-none frame-space-before-none frame-space-after-none frame-no-backgroundimage"><div class="frame-group-container"><div class="frame-group-inner"><div class="frame-container frame-container-default"><div class="frame-inner"><div class="frame-header"><h3 class="element-header "><span>Publikationen</span></h3></div><p><strong>2022</strong></p><ul class="list-normal"><li>Sörgel CA, Schmid R, Stadelmann N, Weisbach V, Distel L, Horch RE, Kengelbach-Weigand A. IGF - I and Hyaluronic Acid Mitigate the Negative Effect of Irradiation on Human Skin Keratinocytes. Cancers 2022,14,588 <a href="https://doi.org/10.3390/cancers14030588" target="_blank" rel="noreferrer">doi.org/10.3390/cancers14030588</a> (registering DOI) - 24 Jan 2022</li><li>Aijia Cai, Zeng-Ming Zheng, Marcus Himmler, Dirk W. Schubert, Thomas A. Fuchsluger, Volker Weisbach, Raymund E. Horch and Andreas Arkudas. Schwann Cells Promote Myogenic Differentiation of Myoblasts and Adipogenic Mesenchymal Stromal Cells on Poly-e-Caprolactone-Collagen I-Nanofibers. Cells 2022, 11, 1436; <a href="https://doi.org/10.3390/cells11091436" target="_blank" rel="noreferrer">doi.org/10.3390/cells11091436</a></li><li>Schneider S, Reißig J, Weisbach V, Achenbach, S, Strobel J, Hackstein H (2022) Protein S Erlangen: a novel PROS1 gene mutation associated with quantitative protein S deficiency<br><a href="https://doi.org/10.1097/MBC.0000000000001120" target="_blank" class="link link-external" rel="noreferrer">https://doi.org/10.1097/MBC.0000000000001120</a></li><li>Bernhard Friedrich, Stefan Lyer, Christina Janko, Harald Unterweger, Regine Brox, Sarah Cunningham, Silvio Dutz, Nicola Taccardi, Floris J Bikker, Katrin Hurle, Heidi Sebald, Malte Lenz, Erdmann Spiecker, Lars Fester, Holger Hackstein, Richard Strauß, Aldo R Boccaccini, Christian Bogdan, Christoph Alexiou, Rainer Tietze. Scavenging of bacteria or bacterial products by magnetic particles functionalized with a broad-spectrum pathogen recognition receptor motif offers diagnostic and therapeutic applications, <a href="https://pubmed.ncbi.nlm.nih.gov/34999260/" target="_blank" class="link link-external" rel="noreferrer">Acta Biomater2022 Mar 15; 141:418-428.doi: 10.1016/j.actbio.2022.01.001. Epub 2022 Jan 7.</a></li><li>Deborah Schmitz | Jan W. Robering1,2 | Volker Weisbach3 | Andreas Arkudas1 | Ingo Ludolph1 | Raymund E. Horch1 | Anja M. Boos1,2 | Annika Kengelbach-Weigand1. Specific features of ex-obese patients significantly influence the functional cell properties of adipose-derived stromal cells. <a href="https://pubmed.ncbi.nlm.nih.gov/35818175/" target="_blank" class="link link-external" rel="noreferrer">J Cell Mol Med. 2022; 26:4463–4478</a></li><li>Schneider A*, Messerer DAC*, Kühn V, Horneffer A, Bugaj TJ, Nikendei C, Kühl M, Kühl SJ. Randomised controlled monocentric trial to compare the impact of using professional actors or peers for communication training in a competency-based inverted biochemistry classroom in preclinical medical education. BMJ Open. 2022 May <a href="https://pubmed.ncbi.nlm.nih.gov/35618331/" target="_blank" class="link link-external" rel="noreferrer">26;12(5):e050823. doi: 10.1136/bmjopen-2021-050823.</a><br> PMID: 35618331; PMCID: PMC9137345. *equally contributed first authorship</li><li>Messerer DAC, Gaessler H, Hoffmann A, Gröger M, Benz K, Huhn A, Hezel F, Calzia E, Radermacher P, Datzmann T. The H2S Donor Sodium Thiosulfate (Na2S2O3) Does Not Improve Inflammation and Organ Damage After Hemorrhagic Shock in Cardiovascular Healthy Swine. Front Immunol. 2022 Jun 16;13:901005. <a href="https://pubmed.ncbi.nlm.nih.gov/35784322/" target="_blank" class="link link-external" rel="noreferrer">doi: 10.3389/fimmu.2022.901005.</a> PMID: 35784322; PMCID: PMC9243230.</li><li>Datzmann T, Messerer DAC, Münz F, Hoffmann A, Gröger M, Mathieu R, Mayer S, Gässler H, Zink F, McCook O, Merz T, Scheuerle A, Wolfschmitt EM, Thebrath T, Zuech S, Calzia E, Asfar P, Radermacher P, Kapapa T. The effect of targeted hyperoxemia in a randomized controlled trial employing a long-term resuscitated, model of combined acute subdural hematoma and hemorrhagic shock in swine with coronary artery disease: An exploratory, hypothesis-generating study. Front Med (Lausanne). 2022 Aug 22;9:971882. <a href="https://pubmed.ncbi.nlm.nih.gov/36072939/" target="_blank" class="link link-external" rel="noreferrer">doi: 10.3389/fmed.2022.971882.</a><br> PMID: 36072939; PMCID: PMC9442904. *equally contributed first authorship</li><li>Föhr KJ, Rapp M, Fauler M, Zimmer T, Jungwirth B, Messerer DAC. Block of Voltage-Gated Sodium Channels by Aripiprazole in a State-Dependent Manner. Int J Mol Sci 2022; 23: 12890.</li><li>Görner S, Heim C, Weigmann B, von Silva-Tarouca B, Kuckhahn A, Ramsperger-Gleixner M, Zimmermann R, Weyand M, Ensminger SM. Direct Impact of Human Platelets on the Development of Transplant Arteriosclerosis. Transplantation 2022; 106: 1180-1192</li><li>Kretschmann S, Völkl S, Reimann H, Krönke G, Schett G, Achenbach S, Lutzny-Geier G, Müller F, Mougiakakos D, Dingfelder J, Flamann C, Hanssens L, Gary R, Mackensen A, Aigner M. Successful Generation of CD19 Chimeric Antigen Receptor T Cells from Patients with Advanced Systemic Lupus Erythematosus. Transplant Cell Ther 2022: S2666-6367</li><li>Lévy S, Heiss R, Grimm R, Grodzki D, Hadler D, Voskrebenzev A, Vogel-Claussen J, Fuchs F, Strauss R, Achenbach S, Hinsen M, Klett D, Schmid J, Kremer AE, Uder M, Nagel AM, Bickelhaupt S. Free-Breathing Low-Field MRI of the Lungs Detects Functional Alterations Associated With Persistent Symptoms After COVID-19 Infection. Invest Radiol 2022; 57: 742-751.</li><li>Lin L, Curtin JA, Regis E, Hirsman A, Howard R, Tutino M, Edwards MR, Prosperi M, Simpson A, Rattray M, Custovic A, Johnston SL. A systems immunology approach to investigate cytokine responses to viruses and bacteria and their association with disease. Sci Rep 2022; 12: 13463.</li><li>Münch F, Purbojo A, Wenzel F, Kohl M, Dittrich S, Rauh M, Zimmermann R, Kwapil N. Verbesserte Qualität gelagerter Erythrozytenkonzentrate durch maschinelle Autotransfusion. Anästhesiologie 2022; 71: 882–892.</li><li>Schmitz D, Robering JW, Weisbach V, Arkudas A, Ludolph I, Horch RE, Boos AM, Kengelbach-Weigand A. Specific features of ex-obese patients significantly influence the functional cell properties of adipose-derived stromal cells. J Cell Mol Med 2022; 26: 4463–4478</li><li>Sommer N, Noack S, Hecker A, Hackstein H, Bein G, Weissmann N, Seeger W, Mayer K, Hecker M. Correction: Sommer et al. Decreased Thymic Output Contributes to Immune Defects in Septic Patients. J. Clin. Med. 2020, 9, 2695. J Clin Med 2022; 11: 4497</li><li>Voskens C, Stoica D, Rosenberg M, Vitali F, Zundler S, Ganslmayer M, Knott H, Wiesinger M, Wunder J, Kummer M, Siegmund B, Schnoy E, Rath T, Hartmann A, Hackstein H, Schuler-Thurner B, Berking C, Schuler G, Atreya R, Neurath MF. Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis. Gut 2022 Apr 15:gutjnl-2022-327075.</li><li>Wasnick R, Korfei M, Piskulak K, Henneke I, Wilhelm J, Mahavadi P, Dartsch RC, von der Beck D, Koch M, Shalashova I, Weiss A, Klymenko O, Askevold I, Fink L, Witt H, Hackstein H, El Agha E, Bellusci S, Klepetko W, Königshoff M, Eickelberg O, Schermuly RT, Braun T, Seeger W, Ruppert C, Guenther A. Notch1 Induces Defective Epithelial Surfactant Processing and Pulmonary Fibrosis. Am J Respir Crit Care Med 2022 Sep 1. doi: 10.1164/rccm.202105-1284OC. Online ahead of print.</li><li>Welters C, Lammoglia Cobo MF, Stein CA, Hsu MT, Ben Hamza A, Penter L, Chen X, Buccitelli C, Popp O, Mertins P, Dietze K, Bullinger L, Moosmann A, Blanc E, Beule D, Gerbitz A, Strobel J, Hackstein H, Rahn HP, Dornmair K, Blankenstein T, Hansmann L. Immune Phenotypes and Target Antigens of Clonally Expanded Bone Marrow T Cells in Treatment-Naïve Multiple Myeloma. Cancer Immunol Res 2022; 10: 1407-1419.</li><li>Wohlgemuth L, Stratmann AEP, Münnich F, Bernhard S, Thomaß BD, Münnich F, Mohamed AOK, Mannes M, Schmidt CQ, Nilsson Ekdahl K, Nilsson B, Fauler M, Föhr KJ, Huber-Lang M, Messerer DAC. Modulation of Neutrophil Activity by Soluble Complement Cleavage Products-An In-Depth Analysis. Cells 2022; 11: 3297.</li><li>Wygrecka M, Wujak L, Markart P, Kosanovic D, Müller-Redetzky HC, Witzenrath M, Henneke I, Schermuly RT, Seeger W, Schaefer L, Kwapiszewska G, Marsh LM, Baal N, Hackstein H, Maat S, Maas C. Erratum: Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury. Am J Respir Crit Care Med 2022; 206: 1184.</li><li>Friedrich, B., Eichermüller, J., Bogdan, C., Cunningham, S., Hackstein, H., Strauß, R., Alexiou, C., Lyer, S., Tietze, R., 2022a. Biomimetic Magnetic Particles for the Removal of Gram-Positive Bacteria and Lipoteichoic Acid. Pharmaceutics 14, 2356. <a href="https://doi.org/10.3390/pharmaceutics14112356" target="_blank" rel="noreferrer">https://doi.org/10.3390/pharmaceutics14112356</a></li><li>Messerer DAC, Behr JL, Kraft SF, Schön M, Horneffer A, Kühl SJ, Seifert LB, Huber-Lang M, Böckers TM, Böckers A: The Gross Anatomy Course: SARS-CoV-2 pandemic-related effects on students' learning, interest in peer-teaching, and students' perception of its importance Anat Sci Educ. 2022 Dec 23. doi: 10.1002/ase.2245. Online ahead of print.</li></ul><p><strong>Vorträge mit Abstract 2022</strong></p><ul class="list-normal"><li>Pfeiffer H, Opel D, Strobel S, Hackstein H, Achenbach S: Impact of different collection rates on the collection effciency of peripheral blood stem cells. Vortrag auf dem Kongress der Deutschen Gesellschaft f ur Transfusionsmedizin und Immunh amatologie (DGTI), Mannheim, 21.-23.09.2022. Abstract in: Transfus Med Hemother 2022; 49(suppl 1):5-88.</li><li>Ben Hamza, A., Welters, C., Brüggemann, M., Dietze, K., Bullinger, L., Brümmendorf, T.H., Strobel, J., Hackstein, H., Dornmair, K., Beier, F., Hansmann, L. Clonal dynamics, immune phenotypes, and targets of bone marrow-infiltrating T cells in acquired aplastic anemia. HemaSphere 2022, Volume 6, doi: 10.1097/01.HS9.0000843548.14401.e2</li></ul><p><strong>Vorträge ohne Abstract 2022</strong></p><ul class="list-normal"><li>Al Moussa E, Bender A, Hackstein H, Messerer D, Strobel J, Weisbach V, Weiss D, Zimmermann R. Online-Fortbildungsveranstaltung der Bayerischen Landesärztekammer „Qualifikation als Transfusionsverantwortlicher/ Transfusionsbeauftragter”, Erlangen, 25./26.11.2022</li><li>Hackstein H, Hirsman A, Kramer R, Messerer D, Pfeiffer H, Strobel J, Weiss D, Zimmermann R. 6. Frühjahrssymposium Gerinnung Erlangen 2022, Erlangen, 25.06.2022.</li><li>Zimmermann R. Akute Gerinnungsstörungen – physiologische Grundlagen und Labordiagnostik. Blutungen unter Antikoagulation. 2 Vorträge beim Aufbau-Kurs Internistische Intensivmedizin, Medizinische Klinik 1, Universitätsklinikum Erlangen, 21.01.2021</li><li>Zimmermann R. Perioperatives Gerinnungsmanagement: Diagnostische Aspekte aus Sicht der Transfusionsmedizin. Vortrag bei den Transfusionsmedizinischen Gesprächen Hannover, BDT, Online-Veranstaltung, 04.02.2022</li><li>Zimmermann R. Der aktuelle Fall: Faktor XIII und blutsparende Verfahren. Vortrag bei der Hybridveranstaltung 32. Netzwerktreffen „Perioperative Gerinnung“ Nordbayern, 09.02.2022</li><li>Zimmermann R. Patient Blood Management und Gerinnungsmanagement: Update aus Sicht der Transfusionsmedizin. Vortrag auf der Fortbildungsveranstaltung “Patient Blood Management & Bleeding Card”, Ulm, 29./30.04.2022</li><li>Zimmermann R. Aktuelles zu Patient Blood Management und Gerinnungsmanagement. Vortrag bei der Mittwochs-Fortbildung der Transfusionsmedizinischen und Hämostaseologischen Abteilung, UK Erlangen, 04.05.2022</li><li>Zimmermann R. Aktuelles zu Transfusionseinleitung, -durchführung und -dokumentation unter Berücksichtigung der Gesamtnovelle 2017 der Hämotherapie-Richtlinie. Fortbildungsvortrag im Klinikum am Europakanal, Erlangen, 25.05.2022</li><li>Zimmermann R. Delayed Transfusion – das zunehmende Problem des vermeidbaren Transfusions-Notfalls. Aussagekraft spezieller Gerinnungsdiagnostik, dargestellt anhand klinischer Beispiele. 2 Vorträge beim Refresherkurs für Transfusionsbeauftragte und Transfusionsverantwortliche, Landesärztekammer Thüringen, Jena, 31.05.2022</li><li>Zimmermann R. Transfusionsrisiken unter Berücksichtigung der aktuellsten Hämovigilanz-Daten des PEI und der SHOT-Gruppe. Vortrag bei der Mittwochs-Fortbildung der Transfusionsmedizinischen und Hämostaseologischen Abteilung, UK Erlangen, 08.06.2022</li><li>Zimmermann R. Next Generation Sequencing in der Gerinnungsdiagnostik - Interessante Gerinnungsfälle mit identifizierten genetischen Varianten aus unseren Ambulanzen. Vortrag bei der Mittwochs-Fortbildung der Transfusionsmedizinischen und Hämostaseologischen Abteilung, UK Erlangen, 15.06.2022</li><li>Zimmermann R. Sinusvenenthrombose – Ursachen, Antikoagulation / Neues zu Genese und Antikoagulation bei Anti-Phospholipid-Syndrom / Interessante Gerinnungsfälle mit identifizierten genetischen Varianten aus unseren Ambulanzen. 3 Vorträge auf dem 6. Frühjahrssymposium Gerinnung, Erlangen, 25.06.2022.</li><li>Zimmermann R. Blutprodukteherstellung Transfusionsmedizin. Vortrag auf dem Bundeswehr Medizintechnik Lehrgang - Erlangen 2022, 26.09.2022</li><li>Zimmermann R. Ergänzung spezieller Gerinnungsdiagnostik durch Molekulargenetik, dargestellt anhand klinischer Beispiele. Vortrag auf dem 33. Treffen des Netzwerks Perioperative Gerinnung Nordbayern, Geiselwind, 28.09.2022</li><li>Strobel J. Herausforderungen der Coronavirus-Pandemie für die Blutversorgung in der Klinik. Vortrag auf dem 33. Treffen des Netzwerks Perioperative Gerinnung Nordbayern, Geiselwind, 28.09.2022</li><li>Zimmermann R. Präoperative Diagnostik und Therapie von Hämostasestörungen / Therapie mit gerinnungsaktiven Hämotherapeutika / Notfall- und Massivtransfusion. 3 Vorträge auf dem Online-Kurs für Transfusionsverantwortliche/ -beauftragte, Akademie für Ärztliche Fortbildung, Rheinland-Pfalz, 15.11.2022</li><li>Zimmermann R. Vergangene und künftige Veränderungen im Erythrozytenverbrauch: Informationen aus Diagnose- und Verbrauchsstatistiken. Vortrag auf dem Workshop klinische Hämotherapie der Arbeitsgemeinschaft der Ärzte staatlicher und kommunaler Bluttransfusionsdienste e.V., Erlangen, 17.11.2022</li><li>Zimmermann R. Versorgungsstrategien bei Thrombozytenrefraktärität. Vortrag bei der Mittwochs-Fortbildung der Transfusionsmedizinischen und Hämostaseologischen Abteilung, UK Erlangen, 23.11.2022</li><li>Zimmermann R. Höchstrichterliche Rechtsprechung im Transfusionsrecht. Vortrag bei der Mittwochs-Fortbildung der Transfusionsmedizinischen und Hämostaseologischen Abteilung, UK Erlangen, 30.11.2022</li><li>Ben Hamza A, Welters C, Brüggemann M, Dietze K, Bullinger L, Brümmendorf TH, Strobel J, Hackstein H, Dornmair K, Beier F, Hansmann L. Klon-Assoziierte Immunphänotypen und Zielstrukturen von Knochenmark-Iinfiltrierenden T-Zellen in erworbener aplastischer Anämie. DGHO 2022 (Vortrag).</li></ul><p><strong>Sonstiges 2022</strong></p><ul class="list-normal"><li>Zimmermann R. Organisation und Leitung des Workshops klinische Hämotherapie der Arbeitsgemeinschaft der Ärzte staatlicher und kommunaler Bluttransfusionsdienste e.V., Novotel Erlangen, 17.11.2022</li><li>Ben Hamza A, Welters C, Brüggemann M, Dietze K, Bullinger L, Brümmendorf TH, Winkler T, Strobel J, Hackstein H, Dornmair K, Beier F, Hansmann L. Clonally expanded T Cells in aquired aplastic anemia Bone marrow display cytotoxic effector phenoteypes and can recognize hematopoitetic progenitor cells. 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Order can be changed. --><div class="pswp__counter"></div><button class="pswp__button pswp__button--close" title="Close (Esc)"></button><button class="pswp__button pswp__button--share" title="Share"></button><button class="pswp__button pswp__button--fs" title="Toggle fullscreen"></button><button class="pswp__button pswp__button--zoom" title="Zoom in/out"></button><!-- Preloader demo https://codepen.io/dimsemenov/pen/yyBWoR --><!-- element will get class pswp__preloader--active when preloader is running --><div class="pswp__preloader"><div class="pswp__preloader__icn"><div class="pswp__preloader__cut"><div class="pswp__preloader__donut"></div></div></div></div></div><div class="pswp__share-modal pswp__share-modal--hidden pswp__single-tap"><div class="pswp__share-tooltip"></div></div><button class="pswp__button pswp__button--arrow--left" title="Previous (arrow left)"></button><button class="pswp__button pswp__button--arrow--right" title="Next (arrow right)"></button><div class="pswp__caption"><div class="pswp__caption__center"></div></div></div></div></div><!-- Modal --><div class="modal fade" id="imageUsingRightsModal" tabindex="-1" aria-label="Fotorechte" aria-hidden="true"><div class="modal-dialog modal-dialog-centered"><div class="modal-content"><div class="modal-header"><h6 class="mb-0">Fotorechte</h6><button type="button" class="btn-close" data-bs-dismiss="modal" aria-label="Close"></button></div><div class="modal-body"> Die Fotos dürfen (mit Angabe der Quelle: "Uniklinikum Erlangen") kostenfrei für die redaktionelle Berichterstattung verwendet werden; die kommerzielle Nutzung ist nur nach ausdrücklicher Genehmigung durch das Uniklinikum Erlangen gestattet. </div></div></div></div></div> <!-- Matomo --> <script type="text/javascript"> var _paq = _paq || []; // Call disableCookies before calling trackPageView to avoid any cookies _paq.push(['disableCookies']); _paq.push(['trackPageView']); _paq.push(['enableLinkTracking']); // accurately measure time spent on the last pageview // set the default heart beat interval to 30 seconds _paq.push(['enableHeartBeatTimer', 30]); (function() { var u="//matomo.uk-erlangen.de/"; _paq.push(['setTrackerUrl', u+'piwik.php']); _paq.push(['setSiteId', 40]); var d=document, g=d.createElement('script'), s=d.getElementsByTagName('script')[0]; g.type='text/javascript'; g.async=true; g.defer=true; g.src=u+'piwik.js'; s.parentNode.insertBefore(g,s); })(); </script> <noscript><p><img src="https://matomo.uk-erlangen.de/piwik.php?idsite=40&rec=1" style="border:0;" alt="" /></p></noscript> <!-- End Matomo Code --> <script src="/_assets/d62557c271d06262fbb7ce0981266e2f/Javascript/auto-complete.min.1732120249.js"></script> <script src="/_assets/9b80d86a98af3ecc38aabe297d2c3695/Contrib/photoswipe/photoswipe-dynamic-caption-plugin.umd.min.1692024263.js"></script> <script src="/_assets/948410ace0dfa9ad00627133d9ca8a23/JavaScript/Powermail/Form.min.1731397780.js" defer="defer"></script> <script> const searchForms = document.querySelectorAll('input[name="tx_kesearch_pi1[sword]"]'); let keSearchPremiumAutocomplete = []; searchForms.forEach(function (el) { let fieldId = el.id; keSearchPremiumAutocomplete.push(new autoComplete({ selector: 'input[id="' + fieldId + '"]', minChars: 2, source: function (term, response) { term = term.toLowerCase(); httpRequest = new XMLHttpRequest(); if (!httpRequest) { alert('Giving up :( Cannot create an XMLHTTP instance'); return false; } httpRequest.onreadystatechange = function () { if (httpRequest.readyState == 4) { response(JSON.parse(httpRequest.responseText)) } }; httpRequest.open('GET', 'https://www.transfusionsmedizin.uk-erlangen.de/index.php?eID=keSearchPremiumAutoComplete' + '&wordStartsWith=' + term + '&amount=10' + '&pid=1029329' + '&language=0' ); httpRequest.send(); } })); }); </script> </body> </html>