Passiflora incarnata in the treatment of attention-deficit h

<!DOCTYPE html> <html lang="ta"> <head> <meta charset="utf-8"> <meta name="viewport" content="width=device-width, initial-scale=1"> <title>Passiflora incarnata in the treatment of attention-deficit h | 11150</title> <meta name="keywords" content="Shahin Akhondzadeh, MR Mohammadi and F Momeni, "/> <meta name="description" content="Background: Attention-deficit hyperactivity disorder (ADHD) is a common early-onset childhood disorder that is estimated to occur in 3 to 5% of school-aged..11150"/> <meta name="citation_publisher" content="திறந்த அணுகல் இதழ்கள்" /> <meta name="citation_journal_title" content="மருத்துவ பயிற்சி"> <meta name="citation_title" content="Passiflora incarnata in the treatment of attention-deficit hyperactivity disorder in children and adolescents"> <meta name="citation_author" content="Shahin Akhondzadeh" /> <meta name="citation_author" content="MR Mohammadi" /> <meta name="citation_author" content="F Momeni" /> <meta name="citation_year" content=""> <meta name="citation_volume" content="2"> <meta name="citation_issue" content="4"> <meta name="citation_abstract" content="Background: Attention-deficit hyperactivity disorder (ADHD) is a common early-onset childhood disorder that is estimated to occur in 3 to 5% of school-aged children. Stimulants are the first-line medication in the pharmacotherapy of ADHD. Nevertheless, approximately 30% of children and adolescents either do not respond to or do not tolerate stimulants. Therefore, new treatments, including alternative medicine, are still needed. Passion flower consists of the fragmented or cut, dried aerial parts of Passiflora incarnata L., and is a folk remedy for anxiety and ADHD. However, there is no evidence-based document that confirms its efficacy in the treatment of ADHD. Objectives: We hypothesized that passion flower would be beneficial for the treatment of ADHD and report the results of a controlled trial of tablets of passion flower and methylphenidate in the treatment of this disorder. Patients & methods: A total of 34 children with ADHD as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM IV) were randomized to receive tablets of passiflora or methylphenidate, dosed on a weight-adjusted basis. Group 1 received passiflora 0.04 mg/kg/day (twice daily) and group 2 received methylphenidate 1 mg/kg/day (twice daily) in an 8-week, doubleblind, randomized clinical trial. The principal measure of outcome was the Parent and Teacher ADHD Rating Scale. Patients were assessed by a child psychiatrist at baseline, 14, 28, 42 and 56 days after the medication was started. Results: No significant differences were observed between passiflora and methylphenidate on the Parent and Teacher Rating Scale scores over the course of the trial (F = 0.007, df = 1, p = 0.93; and F = 0.006, df = 1, p = 0.94, respectively). Both treatment groups demonstrated significant clinical benefit over the period of treatment as assessed by both parents and teachers. Although the number of dropouts in the methylphenidate group was higher than in the Passiflora group, there was no significant difference between the two protocols in terms of dropouts. In addition, decreased appetite and anxiety/nervousness were observed more often in the methylphenidate group. Conclusions: The results suggest that passiflora may be a novel therapeutic agent for the treatment of ADHD. In addition, a tolerable sideeffect profile may be considered as one of the advantages of passiflora. Nevertheless, our study is relatively small and our results require confirmation in a larger study. 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<div class="col-md-7 sm-margin-b-30"> <h2 class="breadcrumbs-v5-title">மருத்துவ பயிற்சி</h2> </div> </div> </div> </section> <style> .breadcrumbs-v5 { position: relative; z-index: 1; background: url(https://www.openaccessjournals.com/admin/banners/clinical-practice-therapy-banner.jpg) no-repeat; background-size: cover; background-position: 50% 20%; padding: 80px 0 80px; text-align:center; } .breadcrumbs-v5 .breadcrumbs-v5-title { font-size: 60px; } #issn{ line-height:30px; color:#fff; } </style> <div class="bg-color-sky-light">  <div class="content container"> <div class="row"> <div class="col-md-12 md-margin-b-50">  <article class="blog-grid margin-b-30"> <div class="blog-grid-content">  <h3 class="blog-grid-title-lg">சுருக்கம்</h3> <h1 class="fweight-400 font-size-26"> Passiflora incarnata in the treatment of attention-deficit hyperactivity disorder in children and adolescents </h1> Shahin Akhondzadeh, MR Mohammadi and F Momeni<br /><br /> <p style=\"\\"text-align:\">Background: Attention-deficit hyperactivity disorder (ADHD) is a common early-onset childhood disorder that is estimated to occur in 3 to 5% of school-aged children. Stimulants are the first-line medication in the pharmacotherapy of ADHD. Nevertheless, approximately 30% of children and adolescents either do not respond to or do not tolerate stimulants. Therefore, new treatments, including alternative medicine, are still needed. Passion flower consists of the fragmented or cut, dried aerial parts of Passiflora incarnata L., and is a folk remedy for anxiety and ADHD. However, there is no evidence-based document that confirms its efficacy in the treatment of ADHD. Objectives: We hypothesized that passion flower would be beneficial for the treatment of ADHD and report the results of a controlled trial of tablets of passion flower and methylphenidate in the treatment of this disorder. Patients & methods: A total of 34 children with ADHD as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM IV) were randomized to receive tablets of passiflora or methylphenidate, dosed on a weight-adjusted basis. Group 1 received passiflora 0.04 mg/kg/day (twice daily) and group 2 received methylphenidate 1 mg/kg/day (twice daily) in an 8-week, doubleblind, randomized clinical trial. The principal measure of outcome was the Parent and Teacher ADHD Rating Scale. Patients were assessed by a child psychiatrist at baseline, 14, 28, 42 and 56 days after the medication was started. Results: No significant differences were observed between passiflora and methylphenidate on the Parent and Teacher Rating Scale scores over the course of the trial (F = 0.007, df = 1, p = 0.93; and F = 0.006, df = 1, p = 0.94, respectively). Both treatment groups demonstrated significant clinical benefit over the period of treatment as assessed by both parents and teachers. Although the number of dropouts in the methylphenidate group was higher than in the Passiflora group, there was no significant difference between the two protocols in terms of dropouts. In addition, decreased appetite and anxiety/nervousness were observed more often in the methylphenidate group. Conclusions: The results suggest that passiflora may be a novel therapeutic agent for the treatment of ADHD. In addition, a tolerable sideeffect profile may be considered as one of the advantages of passiflora. Nevertheless, our study is relatively small and our results require confirmation in a larger study.</p> <div class="alert alert-info text-left"><b>:</b> </div> </div> </article> </div> </div> </div> </div>  <footer id="footer" class="cu_footer"> <div class="container"> <div class="row padding-t-20 padding-b-20"> <div class="col-md-10"> <ul> <li ><a href="https://tamil.openaccessjournals.com/">வீடு</a></li> <li ><a href="https://tamil.openaccessjournals.com/about-us.html">எங்களை பற்றி</a></li> <li ><a href="https://tamil.openaccessjournals.com/journals.html">இதழ்கள்</a></li> <li ><a href="https://tamil.openaccessjournals.com/instructionsforauthors.html">ஆசிரியர் வழிகாட்டுதல்கள்</a></li> <li ><a href="https://tamil.openaccessjournals.com/contact-us.html">எங்களை தொடர்பு கொள்ள</a></li> </ul>  </div> <div class="col-md-2">  <ul class="list-inline ul-li-lr-2 text-right sm-text-center margin-b-0"> <li class="animate-theme-icons"> <a class="animate-theme-icons-body animate-theme-icons-white-bg theme-icons-md radius-3" href="https://www.facebook.com/profile.php?id=100076418779107" target="_blank"> <i class="animate-theme-icons-element fa fa-facebook"></i> </a> </li> <li class="animate-theme-icons"> <a class="animate-theme-icons-body animate-theme-icons-white-bg theme-icons-md radius-3" href="https://twitter.com/OpenaccessJ" target="_blank"> <i class="animate-theme-icons-element fa fa-twitter"></i> </a> </li> <li class="animate-theme-icons"> <a class="animate-theme-icons-body animate-theme-icons-white-bg theme-icons-md radius-3" href="https://www.linkedin.com/company/open-access-journal" target="_blank"> <i class="animate-theme-icons-element fa fa-linkedin"></i> </a> </li> <li class="animate-theme-icons"> <a class="animate-theme-icons-body animate-theme-icons-white-bg theme-icons-md radius-3" href="https://www.instagram.com/openaccess_journals/" target="_blank"> <i class="animate-theme-icons-element fa fa-instagram"></i> </a> </li> </ul>  </div> </div>  <div class="footer-v2-copyright"> <p class="pclas"><a href="https://tamil.openaccessjournals.com/" title="இங்கே கிளிக் செய்யவும்" class="color-white">திறந்த அணுகல் இதழ்கள்</a> © 2025</p> </div>  </div> <div class="app-view"> Get the App <p><a href="https://play.google.com/store/apps/details?id=com.journals.openaccessjournals" target="_blank"><i class="fa fa-android" aria-hidden="true"></i></a></p> </div> </footer>    <div class="sidebar-content-overlay"></div>   <a href="javascript:void(0);" class="js-back-to-top back-to-top-theme"></a> <script async type="text/javascript" src="https://tamil.openaccessjournals.com/assets/plugins/jquery.migrate.min.js"></script> <script async type="text/javascript" src="https://tamil.openaccessjournals.com/assets/plugins/bootstrap/js/bootstrap.min.js"></script>   <script async type="text/javascript" src="https://tamil.openaccessjournals.com/assets/plugins/jquery.back-to-top.js"></script> <script async type="text/javascript" src="https://tamil.openaccessjournals.com/assets/plugins/jquery.equal-height.js"></script>   <script async src="https://app.wabi-app.com/widget/js/wabi.js?phone_number=+44-1704-335730&lang=en&position=left"></script> </div> </body> </html>

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Passiflora incarnata in the treatment of attention-deficit h | 11150