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ul li a:hover, .gt-social-links-element.gt-style-7 ul li a:focus, .gt-event-buttons ul li a, .gt-event-buttons ul li a:visited, .gt-content-detail-box > ul > li.gt-event-counter, .gt-button.gt-style-3 a, .gt-button.gt-style-3 a:visited, .gt-button.gt-style-2 a, .gt-button.gt-style-2 a:visited, .gt-button.gt-style-1 a, .gt-button.gt-style-1 a:visited, .gt-app-box .gt-item a:hover, .gt-app-box .gt-item a:focus, .gt-blog-carousel .gt-slider-prev:hover, .gt-blog-carousel .gt-slider-prev:focus, .gt-blog-carousel .gt-slider-next:hover, .gt-blog-carousel .gt-slider-next:focus, .gt-blog-carousel .gt-all-button:hover, .gt-blog-carousel .gt-all-button:focus, .gt-dark .gt-slider-prev:hover, .gt-dark .gt-slider-prev:focus, .gt-dark .gt-slider-next:hover, .gt-dark .gt-slider-next:focus, .gt-dark .gt-all-button:hover, .gt-dark .gt-all-button:focus, .gt-events-carousel .gt-slider-prev:hover, .gt-events-carousel .gt-slider-prev:focus, .gt-events-carousel .gt-slider-next:hover, .gt-events-carousel .gt-slider-next:focus, .gt-events-carousel .gt-all-button:hover, .gt-events-carousel .gt-all-button:focus, .gt-testimonials-carousel .gt-slider-pagination .swiper-pagination-bullet:hover, .gt-testimonials-carousel .gt-slider-pagination .swiper-pagination-bullet:focus, .gt-testimonials-carousel .gt-slider-pagination .swiper-pagination-bullet.swiper-pagination-bullet-active, .gt-categorized-contents .gt-all-button:hover, .gt-categorized-contents .gt-all-button:focus, .gt-categorized-contents .gt-nav > li > a, .gt-categorized-contents .gt-nav > li > a:visited, .gt-eventchamp-slider .gt-slider-content .gt-buttons a:hover, .gt-eventchamp-slider .gt-slider-content .gt-buttons a:focus, .gt-countdown-slider.gt-style-3 > .gt-slider-content .gt-buttons a:hover, .gt-countdown-slider.gt-style-3 > .gt-slider-content .gt-buttons a:focus, .gt-countdown-slider.gt-style-2 > .gt-slider-content .gt-buttons a:hover, .gt-countdown-slider.gt-style-2 > .gt-slider-content .gt-buttons a:focus, .gt-countdown-slider.gt-style-1 > .gt-slider-content .gt-buttons a:hover, .gt-countdown-slider.gt-style-1 > .gt-slider-content .gt-buttons a:focus, .gt-events-slider .gt-slide-inner .gt-content .buttons a:hover, .gt-events-slider .gt-slide-inner .gt-content .buttons a:focus, .gt-events-slider .gt-slide-inner .gt-content .gt-category, .gt-eventchamp-service-box.gt-style-1:hover .gt-icon, .gt-mobile-menu .gt-bottom .gt-user-box, .gt-header.gt-style-1.gt-style-2 .gt-elements .gt-user-box, .gt-header.gt-style-3.gt-style-4 .gt-elements .gt-user-box, .gt-header.gt-style-5.gt-style-6 .gt-elements .gt-user-box, .gt-style-4 .sk-fading-circle .sk-circle:before, .gt-style-3 .spinner, .gt-style-2 .spinner > div, .gt-style-1 .double-bounce1, .gt-style-1 .double-bounce2, .gt-event-style-1 .gt-category ul li, .gt-event-style-1 .gt-price, .gt-event-style-3 .gt-category ul li, .gt-event-style-4 .gt-category ul li, .gt-venue-style-1 .gt-image .price, .gt-venue-style-3 .gt-image .price, .gt-venue-style-3 .gt-location, .gt-venue-style-3 .gt-location a, .gt-venue-style-3 .gt-location a:visited, .fc button, .fc-state-default, .fc-event, .fc-event-dot, .ui-datepicker .ui-datepicker-today > a, .ui-datepicker .ui-datepicker-today > a:visited, .ui-datepicker .ui-datepicker-header, .plyr--video .plyr__controls button.tab-focus:focus, .plyr--video .plyr__controls button:hover, .plyr--audio .plyr__controls button.tab-focus:focus, .plyr--audio .plyr__controls button:hover, .plyr__play-large, button, input[type="submit"], .widget_tag_cloud .tagcloud a:hover, .widget_tag_cloud .tagcloud a:focus, .gt-like-box a.gt-liked, .gt-like-box a.gt-liked:visited, .gt-like-box a.gt-favorited, .gt-like-box a.gt-favorited:visited, .gt-like-box a:hover, .gt-like-box a:focus, .fancybox-container .fancybox-progress, .gt-badge{background-color:#ffbb00;}.widget_archive ul li:before, .widget_categories ul li:before, .widget_pages ul li:before, .widget_meta ul li:before, .widget_recent_comments ul li:before, .widget_recent_entries ul li:before, .widget_nav_menu ul li:before, .fancybox-container .fancybox-thumbs__list a:before, .gt-like-box a.gt-liked, .gt-like-box a.gt-liked:visited, .gt-like-box a.gt-favorited, .gt-like-box a.gt-favorited:visited, .gt-like-box a:hover, .gt-like-box a:focus, .gt-countdown.gt-style-3 ul li > .gt-inner, .gt-footer .gt-app-box .gt-item a:hover, .gt-footer .gt-app-box .gt-item a:focus, .gt-footer.gt-style-1 .gt-app-box .gt-item a:hover, .gt-footer.gt-style-1 .gt-app-box .gt-item a:focus, .gt-post-style-1 .gt-bottom .gt-more, .gt-post-style-1 .gt-bottom .gt-more:visited, .gt-post-style-2 .gt-bottom .gt-more, .gt-post-style-2 .gt-bottom .gt-more:visited, .gt-pagination ul li > span, .gt-pagination ul li > a, .gt-pagination ul li > a:visited, .gt-post-pagination ul li a, .gt-post-pagination ul li a:visited, .gt-event-ticket.gt-style-1.gt-active-on, .gt-event-ticket.gt-style-2.gt-active-on, .gt-event-ticket.gt-style-3.gt-active-on, .gt-event-ticket.gt-style-4, .gt-event-ticket.gt-style-5.gt-active-on, .gt-event-ticket.gt-style-6.gt-active-on, .gt-event-ticket.gt-style-7.gt-active-on, .gt-button.gt-style-3 a, .gt-button.gt-style-3 a:visited, .gt-button.gt-style-2 a, .gt-button.gt-style-2 a:visited, .gt-button.gt-style-1 a:hover, .gt-button.gt-style-1 a:focus, .gt-button.gt-style-1 a, .gt-button.gt-style-1 a:visited, .gt-event-buttons ul li a, .gt-event-buttons ul li a:visited, .gt-event-schedule.gt-style-7 .gt-item > ul > li .gt-content > .gt-inner, .gt-event-schedule.gt-style-2 .gt-schedule-tabs > li > a, .gt-event-schedule.gt-style-2 .gt-schedule-tabs > li > a:visited, .gt-organizers.gt-style-2 ul li a:hover, .gt-organizers.gt-style-2 ul li a:focus, .gt-tags.gt-style-2 ul li a:hover, .gt-tags.gt-style-2 ul li a:focus, .gt-categories.gt-style-2 ul li a:hover, .gt-categories.gt-style-2 ul li a:focus, .gt-social-sharing.gt-style-7 ul li a:hover, .gt-social-sharing.gt-style-7 ul li a:focus, .gt-social-links-element.gt-style-7 ul li a:hover, .gt-social-links-element.gt-style-7 ul li a:focus, .gt-app-box .gt-item a:hover, .gt-app-box .gt-item a:focus, .gt-counter > .gt-number, .gt-testimonials-carousel .gt-slider-pagination .swiper-pagination-bullet:hover, .gt-testimonials-carousel .gt-slider-pagination .swiper-pagination-bullet:focus, .gt-testimonials-carousel .gt-slider-pagination .swiper-pagination-bullet.swiper-pagination-bullet-active, .gt-eventchamp-service-box.gt-style-1 .gt-title, .gt-eventchamp-service-box.gt-style-1 .gt-icon, .gt-blog-carousel .gt-slider-prev:hover, .gt-blog-carousel .gt-slider-prev:focus, .gt-blog-carousel .gt-slider-next:hover, .gt-blog-carousel .gt-slider-next:focus, .gt-blog-carousel .gt-all-button:hover, .gt-blog-carousel .gt-all-button:focus, .gt-dark .gt-slider-prev:hover, .gt-dark .gt-slider-prev:focus, .gt-dark .gt-slider-next:hover, .gt-dark .gt-slider-next:focus, .gt-dark .gt-all-button:hover, .gt-dark .gt-all-button:focus, .gt-venues-carousel.gt-white .gt-slider-prev:hover, .gt-venues-carousel.gt-white .gt-slider-prev:focus, .gt-venues-carousel.gt-white .gt-slider-next:hover, .gt-venues-carousel.gt-white .gt-slider-next:focus, .gt-venues-carousel.gt-white .gt-all-button:hover, .gt-venues-carousel.gt-white .gt-all-button:focus, .gt-events-carousel .gt-slider-prev:hover, .gt-events-carousel .gt-slider-prev:focus, .gt-events-carousel .gt-slider-next:hover, .gt-events-carousel .gt-slider-next:focus, .gt-events-carousel .gt-all-button:hover, .gt-events-carousel .gt-all-button:focus, .gt-categorized-contents .gt-all-button:hover, .gt-categorized-contents .gt-all-button:focus, .gt-categorized-contents .gt-nav > li > a.active, .gt-categorized-contents .gt-nav > li > a.active:visited, .gt-categorized-contents .gt-nav > li > a:hover, .gt-categorized-contents .gt-nav > li > a:focus, .gt-categorized-contents .gt-nav > li > a, .gt-categorized-contents .gt-nav > li > a:visited, .gt-eventchamp-slider .gt-slider-content .gt-buttons a:hover, .gt-eventchamp-slider .gt-slider-content .gt-buttons a:focus, .gt-countdown-slider.gt-style-2 > .gt-slider-content .gt-buttons a:hover, .gt-countdown-slider.gt-style-2 > .gt-slider-content .gt-buttons a:focus, .gt-countdown-slider.gt-style-1 > .gt-slider-content .gt-buttons a:hover, .gt-countdown-slider.gt-style-1 > .gt-slider-content .gt-buttons a:focus, .gt-events-slider .gt-slide-inner .gt-content .buttons a:hover, .gt-events-slider .gt-slide-inner .gt-content .buttons a:focus, .fc button, .fc-state-default, .gt-header.gt-style-1.gt-style-2 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-header.gt-style-3.gt-style-4 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-header.gt-style-5.gt-style-6 .gt-navbar .gt-menu li .gt-dropdown-menu, button, input[type="submit"], button:hover, input[type="submit"]:hover, button:active, input[type="submit"]:active, button:active:hover, input[type="submit"]:active:hover, button:active:focus, input[type="submit"]:active:focus, button:active:visited, input[type="submit"]:active:visited, button:focus, input[type="submit"]:focus, button, input[type="submit"]{border-color:#ffbb00;}.irs-from:after, .irs-to:after, .irs-single:after, .gt-event-style-3 .gt-content, .gt-event-ticket.gt-style-4.gt-active-on:before, .gt-header.gt-style-1.gt-style-2 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-header.gt-style-3.gt-style-4 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-header.gt-style-5.gt-style-6 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-flex-menu{border-top-color:#ffbb00;}.ui-datepicker:before, .gt-page-title-bar .gt-breadcrumb nav > ol > li.gt-item-current, .gt-page-title-bar .gt-breadcrumb nav > ol > li.current-item > span{border-bottom-color:#ffbb00;}.gt-header.gt-style-1 .gt-elements .gt-social-links li a:hover, .gt-header.gt-style-1 .gt-elements .gt-social-links li a:focus, .gt-header.gt-style-1 .gt-navbar .gt-menu li .gt-dropdown-menu li a:hover, .gt-header.gt-style-1 .gt-navbar .gt-menu li .gt-dropdown-menu li a:focus, .gt-header.gt-style-1 .gt-elements .gt-social-links li a:hover, .gt-header.gt-style-1 .gt-elements .gt-social-links li a:focus, .gt-header.gt-style-1 .gt-navbar .gt-menu > li a:hover, .gt-header.gt-style-1 .gt-navbar .gt-menu > li a:focus, .gt-header.gt-style-3 .gt-elements .gt-social-links li a:hover, .gt-header.gt-style-3 .gt-elements .gt-social-links li a:focus, .gt-header.gt-style-3 .gt-navbar .gt-menu li .gt-dropdown-menu li a:hover, .gt-header.gt-style-3 .gt-navbar .gt-menu li .gt-dropdown-menu li a:focus, .gt-header.gt-style-3 .gt-elements .gt-social-links li a:hover, .gt-header.gt-style-3 .gt-elements .gt-social-links li a:focus, .gt-header.gt-style-3 .gt-navbar .gt-menu > li a:hover, .gt-header.gt-style-3 .gt-navbar .gt-menu > li a:focus, .gt-header.gt-style-5 .gt-elements .gt-social-links li a:hover, .gt-header.gt-style-5 .gt-elements .gt-social-links li a:focus, .gt-header.gt-style-5 .gt-navbar .gt-menu li .gt-dropdown-menu li a:hover, .gt-header.gt-style-5 .gt-navbar .gt-menu li .gt-dropdown-menu li a:focus, .gt-header.gt-style-5 .gt-elements .gt-social-links li a:hover, .gt-header.gt-style-5 .gt-elements .gt-social-links li a:focus, .gt-header.gt-style-5 .gt-navbar .gt-menu > li a:hover, .gt-header.gt-style-5 .gt-navbar .gt-menu > li a:focus, .gt-header.gt-style-1 .gt-navbar .gt-menu > li:hover > a:visited, .gt-header.gt-style-3 .gt-navbar .gt-menu > li:hover > a:visited, .gt-header.gt-style-5 .gt-navbar .gt-menu > li:hover > a:visited, .gt-sticky-header .gt-elements .gt-social-links li a:hover, .gt-sticky-header .gt-elements .gt-social-links li a:focus, .gt-sticky-header .gt-navbar .gt-menu li .gt-dropdown-menu li a:hover, .gt-sticky-header .gt-navbar .gt-menu li .gt-dropdown-menu li a:focus, .gt-sticky-header .gt-elements .gt-social-links li a:hover, .gt-sticky-header .gt-elements .gt-social-links li a:focus, .gt-sticky-header .gt-navbar .gt-menu > li a:hover, .gt-sticky-header .gt-navbar .gt-menu > li a:focus, .gt-sticky-header .gt-navbar .gt-menu > li:hover > a, .gt-sticky-header .gt-navbar .gt-menu > li:hover > a:visited .gt-sticky-header .gt-navbar .gt-menu > li:focus > a, .gt-sticky-header .gt-navbar .gt-menu > li:focus > a:visited{color:#6600ff;}.gt-header.gt-style-1 .gt-elements .gt-user-box, .gt-header.gt-style-3 .gt-elements .gt-user-box, .gt-header.gt-style-5 .gt-elements .gt-user-box, .gt-sticky-header .gt-elements .gt-user-box, .gt-countdown-slider.gt-style-1 > .gt-counter:before{background:#6600ff;}.gt-header.gt-style-1 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-header.gt-style-3 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-header.gt-style-5 .gt-navbar .gt-menu li .gt-dropdown-menu, .gt-sticky-header .gt-navbar .gt-menu li .gt-dropdown-menu{border-top-color:#6600ff;}.gt-footer.gt-style-1{background-image: url(http://www.uventia.com/wp-content/uploads/2020/11/Futer-1-scaled.jpg);}.gt-footer.gt-style-2{background-image: url(http://www.uventia.com/wp-content/uploads/2020/11/Futer-1-scaled.jpg);}.gt-page-title-bar .gt-background{background-position: center top;}.gt-page-title-bar .gt-background{background-image: url(http://www.uventia.com/wp-content/uploads/2020/11/Event-2-scaled.jpg);}.gt-page-title-bar .gt-background{opacity:0.4;}.gt-page-title-bar{padding-top:20px;}.gt-page-title-bar{padding-bottom:20px;}.gt-event-schedule.gt-style-1 .gt-dropdown .gt-panel-body .gt-schedule-speakers .gt-list ul li a:hover, .gt-event-schedule.gt-style-1 .gt-dropdown .gt-panel-body .gt-schedule-speakers .gt-list ul li a:focus, .gt-event-schedule.gt-style-2 .gt-dropdown .gt-panel-body .gt-schedule-speakers .gt-list ul li a:hover, .gt-event-schedule.gt-style-2 .gt-dropdown .gt-panel-body .gt-schedule-speakers .gt-list ul li a:focus, .gt-event-schedule.gt-style-3 .gt-dropdown .gt-panel-body .gt-schedule-speakers .gt-list ul li a:hover, .gt-event-schedule.gt-style-3 .gt-dropdown .gt-panel-body .gt-schedule-speakers 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meeting with subject matter experts to evaluate different points of view on how to solve the problems associated with mutagenic impurities.","about": "[vc_row][vc_column width="2/3"][vc_single_image image="9863" img_size="full" alignment="center" style="vc_box_rounded" css=""][/vc_column][vc_column width="1/3"][vc_empty_space height="50px"][eventchamp_modal_button style="2" align="center" inline="false" margin="false" buttontitle="REQUEST BROCHURE" icon="" svg-icon="" text="" shortcode="" iframe=""] [contact-form-7 id="2928" title="request brochure form"] [/eventchamp_modal_button][vc_empty_space height="25px"][eventchamp_button style="2" align="center" inline="false" margin="false" buttonlink="url:https%3A%2F%2Fwww.uventia.com%2Fregistration-4th-annual-genotoxic-impurities-summit-nitrosamines-beyond-2024%2F|title:REGISTER%20NOW" icon="" svg-icon="JTNDaSUyMGNsYXNzJTNEJTIyZmEtcmVndWxhciUyMGZhLXBlbi10by1zcXVhcmUlMjIlM0UlM0MlMkZpJTNF"][vc_empty_space height="25px"][eventchamp_button style="2" align="center" inline="false" margin="false" buttonlink="url:http%3A%2F%2Fwww.uventia.com%2Fsponsorship%2F|title:BECOME%20A%20SPONSOR" icon="" svg-icon=""][/vc_column][/vc_row][vc_row disable_element="yes"][vc_column][vc_column_text] CONFERENCE OVERVIEW Impurities may have a negative effect on the efficacy, safety, and quality of pharmaceutical components and products. The successful development and manufacturing of novel medications now depend heavily on the assessment of the impurity profiles as well as the management and monitoring of those. The diligent identification of nitrosamines and other genotoxic contaminants should be established at every step of drug development in order to comply with growing regulatory requirements and prevent costly recalls. Our online meeting, which we organized in collaboration with industry professionals, aimed to showcase and discuss different perspectives on addressing the challenges caused by mutagenic impurities. We will go over drug impurity profiling techniques that follow regulatory guidelines, as well as useful tips for adhering to recent updates to ICH M7 and Q3D, new nitrosamine regulations, nitrosamine impurities determination and calculation, risk assessment for genotoxic impurities, analytical challenges, development of acceptance criteria and most recent developments in elemental impurity assessment. Reserve your spot for this informative webinar so that you can leave with new ideas and best practices for managing genotoxic and elemental impurities. [/vc_column_text][/vc_column][vc_column][vc_column_text css=""] WE WILL BE FOCUSING ON N-nitrosamines and mutagenic impurities – drug substance quality considerations and in vivo fate of Nitrosamines Emerging focus for drug product assessment for N-nitrosamines – perspective on quality, safety and regulatory environment Toxicological risk assessment of Nitrosamines – challenges and perspectives Reactivities of N-nitrosamines against Common Reagents and Reaction Conditions: Understanding the potential for Purge Setting limits for NDSRIs Nitrite scavengers as excipients for inhibition of N-nitrosamine formation in drug products Addressing NDSRI Risks Using relative potency of mutation and cancer data, to derive AI’s for Nitrosamines Nitrites: the elephant in the room Toxicological risk assessment of genotoxic impurities: derivation and justification of safe limits Safety assessment of non-genotoxic and genotoxic/carcinogenic extractables and leachables Validation of the Enhanced Ames Test for Nitrosamines [/vc_column_text][/vc_column][vc_column][vc_column_text] WHO IS IT FOR? CxO, VP, Directors, Heads, Managers of Genotoxic Impurities/ GTIs/ Genotoxins/ Elemental Impurities Genotoxicity/ Mutagenicity Carcinogenicity/ Carcinogens Genetic Toxicology/ Chemical Toxicology/ Computational Toxicology Analytical Chemistry/ Analytical Development/ Analytical Science Drug Discovery/ Drug Development/ Drug Substance Drug Safety/ Compound Safety Process Chemistry/ Process Development Product Characterisation/ Risk Assessment Pharmacokinetics/ Metabolism Extractables & Leachables API Development/ Degradation Products LC-MS/ Mass Spectrometry Good Laboratory Practice (GLP)/ Good Manufacturing Practice (GMP) Regulatory Affairs & Compliance [/vc_column_text][vc_empty_space][/vc_column][/vc_row][vc_row disable_element="yes"][vc_column width="1/4"][vc_single_image image="9947" img_size="medium" alignment="center" css=""][/vc_column][vc_column width="3/4"][vc_column_text] [Agenda] 4th Annual Genotoxic Impurities Summit: Nitrosamines & Beyond 2024 Download the full summit program to find speaker biographies, case studies, key takeaways, the day's schedule, and details of each session. 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KG ● Charles River Laboratories ● Chugai Pharmaceutical Co., Ltd. ● Croma-Pharma GmbH ● CSL Behring ● Dottikon Exclusive Synthesis AG ● EDQM, Council of Europe ● Excella GmbH & Co. KG ● FARMAK, a.s. ● Fermion Oy ● Fresenius Kabi ● Fresenius Kabi Deutschland GmbH ● FUJIFILM Toyama Chemical ● Gentronix Ltd ● Grunenthal Ecuatoriana Cia. Ltda. ● GSK ● Haleon ● Health and Environmental Sciences Institute (HESI) ● Hemofarm AD ● Hemomont d.o.o. ● Idorsia ● Insight Exposure and Risk Sciences ● Intertek ● Intertek Melbourn ● Intox Private Limited ● Intuitive Fluorescence Imaging, LLC ● Johnson&Johnson ● Konya Food and Agriculture University ● Krka d. d., Novo mesto ● L.Molteni & C. dei F.lli Alitti SpA ● LabAnalysis S.r.l. ● Laboratoires MAYOLY SPINDLER ● Labtim ADRIA d.o.o. ● LangAllan CMC Regulatory Solutions Ltd ● Lek Pharmaceuticals d.d. ● Lhasa Limited ● Lundbeck ● Luye Pharma AG ● Merck Healthcare KGaA ● Midas Pharma GmbH ● MultiCASE Inc ● National Institute of Health Sciences ● Norwich Pharmaceuticals ● Novartis ● Olon S.p.A. ● Orion Pharma ● Pfizer ● Pharmaceutical firm Darnitsa ● Polpharma ● Preclintox Services, LLC ● ProBioGen AG ● Rontis Hellas ● S-IN Soluzioni Informatiche ● Safetree Consulting e.U. ● Sanofi ● SEQENS ● Solvias AG ● State Agency of Medicines ● Swansea University ● Swissmedic ● Takeda ● Takeda Pharmaceuticals ● Tallinn University of Technology ● Teva Pharmaceutical Industries Ltd. ● TEVA Pharmaceutical Works Ltd ● Teva Pharmaceuticals ● ToxMinds BVBA ● UCB ● Vertex Pharmaceuticals ● Viatris ● Waters ● Waters Corporation ● Zakłady Farmaceutyczne Polpharma ● Zentiva Group, a.s. 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KG ● Bracco Imaging SpA ● Perrigo ● Chiesi Farmaceutici SpA ● Advanz Pharma ● Midas Pharma GmbH ● Aptuit an Evotec Company ● Hikma Pharmaceuticals ● Aptuit (Verona) S.r.L., An Evotec Company ● Adamed Pharma S.A. ● fagg-afmps ● World Health Organization (WHO) ● Curia Spain S.A.U. ● Swissmedic ● Albhades ● Finnish Medicines Agency ● Selvita S.A. ● Fresenius Medical Care Deutschland GmbH ● Fresenius Kabi ● IFF ● Teva Ni Ltd ● Bayer AG ● FUJIFILM Toyama Chemical Co., Ltd. ● INEOS Oxide ● Affygility Solutions ● Laboratorium Zdrochem sp. z o.o. ● Zentiva, k.s. ● Janssen ● Bachem AG ● BD ● Jagiellonian Center of Innovation ● Sanofi Chimie ● Venn Life Sciences ● Merck KGaA, Darmstadt, Germany ● Teva Gyogyszergyar Zrt. ● Drug Development Solutions ● Senior Consultant ● Lonza AG ● Alliance Pharmaceuticals Ltd ● Minakem ● B. 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c0.023,0.008,0.045,0.017,0.068,0.025c0.345,0.118,0.685,0.253,1.022,0.406C54.347,37.729,57,41.557,57,46 C57,52.065,52.065,57,46,57z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Start Date</div><div class="gt-inner">December 4, 2024 11:50 am</div></div></li><li class="gt-end-date"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 59 59" xml:space="preserve"> <g> <path d="M50.95,41.13c-0.391-0.391-1.023-0.391-1.414,0L46,44.666l-3.536-3.536c-0.391-0.391-1.023-0.391-1.414,0 s-0.391,1.023,0,1.414l3.536,3.536l-3.536,3.536c-0.391,0.391-0.391,1.023,0,1.414c0.195,0.195,0.451,0.293,0.707,0.293 s0.512-0.098,0.707-0.293L46,47.494l3.536,3.536c0.195,0.195,0.451,0.293,0.707,0.293s0.512-0.098,0.707-0.293 c0.391-0.391,0.391-1.023,0-1.414l-3.536-3.536l3.536-3.536C51.34,42.153,51.34,41.521,50.95,41.13z"/> <path d="M52,34.479V15V5c0-0.553-0.448-1-1-1h-5V1c0-0.553-0.448-1-1-1h-7c-0.552,0-1,0.447-1,1v3H15V1c0-0.553-0.448-1-1-1H7 C6.448,0,6,0.447,6,1v3H1C0.448,4,0,4.447,0,5v10v41c0,0.553,0.448,1,1,1h38.104c2.002,1.26,4.362,2,6.896,2 c7.168,0,13-5.832,13-13C59,40.997,56.154,36.651,52,34.479z M39,2h5v3v3h-5V5V2z M8,2h5v3v3H8V5V2z M2,6h4v3c0,0.553,0.448,1,1,1 h7c0.552,0,1-0.447,1-1V6h22v3c0,0.553,0.448,1,1,1h7c0.552,0,1-0.447,1-1V6h4v8H2V6z M2,55V16h48v17.636 c-0.196-0.063-0.396-0.114-0.596-0.169c-0.185-0.051-0.37-0.101-0.557-0.144c-0.169-0.038-0.34-0.071-0.511-0.102 c-0.244-0.045-0.489-0.082-0.735-0.113c-0.137-0.017-0.273-0.036-0.411-0.049C46.796,33.024,46.399,33,46,33 c-0.338,0-0.669,0.025-1,0.051V32v-2v-9h-9h-2h-7h-2h-7h-2H7v9v2v7v2v9h9h2h7h2h6.636c0.029,0.088,0.065,0.173,0.095,0.26 c0.084,0.243,0.167,0.487,0.266,0.724c0.055,0.133,0.12,0.26,0.18,0.39c0.115,0.254,0.232,0.507,0.363,0.753 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<g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">End Date</div><div class="gt-inner">December 5, 2024 5:00 pm</div></div></li><li class="gt-status"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 52 52" xml:space="preserve"> <g> <path d="M26,0C11.664,0,0,11.663,0,26s11.664,26,26,26s26-11.663,26-26S40.336,0,26,0z M26,50C12.767,50,2,39.233,2,26 S12.767,2,26,2s24,10.767,24,24S39.233,50,26,50z"/> <path d="M38.252,15.336l-15.369,17.29l-9.259-7.407c-0.43-0.345-1.061-0.274-1.405,0.156c-0.345,0.432-0.275,1.061,0.156,1.406 l10,8C22.559,34.928,22.78,35,23,35c0.276,0,0.551-0.114,0.748-0.336l16-18c0.367-0.412,0.33-1.045-0.083-1.411 C39.251,14.885,38.62,14.922,38.252,15.336z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Status</div><div class="gt-inner"><div class="gt-event-status">Upcoming</div></div></div></li><li class="gt-locations"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 54.757 54.757" xml:space="preserve"> <g> <path d="M27.557,12c-3.859,0-7,3.141-7,7s3.141,7,7,7s7-3.141,7-7S31.416,12,27.557,12z M27.557,24c-2.757,0-5-2.243-5-5 s2.243-5,5-5s5,2.243,5,5S30.314,24,27.557,24z"/> <path d="M40.94,5.617C37.318,1.995,32.502,0,27.38,0c-5.123,0-9.938,1.995-13.56,5.617c-6.703,6.702-7.536,19.312-1.804,26.952 L27.38,54.757L42.721,32.6C48.476,24.929,47.643,12.319,40.94,5.617z M41.099,31.431L27.38,51.243L13.639,31.4 C8.44,24.468,9.185,13.08,15.235,7.031C18.479,3.787,22.792,2,27.38,2s8.901,1.787,12.146,5.031 C45.576,13.08,46.321,24.468,41.099,31.431z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Location</div><div class="gt-inner"><ul><li><a href="https://www.uventia.com/location/online/?post_type=event">Online</a></li></ul></div></div></li><li class="gt-ticket-price"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 59.997 59.997" style="enable-background:new 0 0 59.997 59.997;" xml:space="preserve"> <g> <path d="M19.519,21.05c-0.39,0.4-0.38,1.03,0.01,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.3 c0.39-0.391,0.39-1.021,0-1.41C20.539,20.66,19.908,20.66,19.519,21.05z"/> <path d="M16.668,46.56c-0.39,0.391-0.39,1.03,0,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.29 c0.39-0.39,0.39-1.029,0-1.42C17.688,46.17,17.059,46.17,16.668,46.56z"/> <path d="M16.708,23.89c-0.39,0.391-0.39,1.03,0,1.42c0.2,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.39,0.38-1.03-0.01-1.41C17.729,23.5,17.088,23.5,16.708,23.89z"/> <path d="M19.499,49.39c-0.39,0.391-0.39,1.03,0,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.29 c0.39-0.39,0.39-1.029,0-1.42C20.519,49,19.888,49,19.499,49.39z"/> <path d="M25.118,52.28c-0.38,0.399-0.37,1.029,0.02,1.409c0.2,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.72-0.31 c0.38-0.39,0.38-1.021-0.02-1.41C26.138,51.88,25.508,51.88,25.118,52.28z"/> <path d="M22.338,18.21c-0.39,0.399-0.39,1.03,0.01,1.42c0.19,0.189,0.44,0.29,0.7,0.29c0.26,0,0.51-0.101,0.71-0.3 c0.39-0.391,0.39-1.021-0.01-1.41C23.358,17.819,22.729,17.819,22.338,18.21z"/> <path d="M22.328,52.22c-0.39,0.39-0.39,1.021,0,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.51-0.1,0.71-0.29 c0.39-0.399,0.39-1.03,0-1.42S22.708,51.83,22.328,52.22z"/> <path d="M13.888,26.729c-0.39,0.391-0.39,1.03,0.01,1.42c0.19,0.19,0.44,0.29,0.7,0.29c0.26,0,0.51-0.1,0.71-0.3 c0.39-0.39,0.39-1.02-0.01-1.41C14.908,26.34,14.278,26.34,13.888,26.729z"/> <path d="M8.178,38.08c-0.39,0.39-0.39,1.02,0,1.41c0.2,0.199,0.45,0.3,0.71,0.3c0.26,0,0.51-0.101,0.71-0.3 c0.39-0.391,0.39-1.021,0-1.41C9.208,37.689,8.568,37.689,8.178,38.08z"/> <path d="M8.258,32.41c-0.39,0.399-0.39,1.029,0,1.42c0.2,0.189,0.45,0.29,0.71,0.29c0.25,0,0.51-0.101,0.7-0.301 c0.39-0.39,0.39-1.02,0-1.409C9.278,32.02,8.638,32.02,8.258,32.41z"/> <path d="M5.438,35.25c-0.39,0.399-0.39,1.03,0,1.42c0.2,0.189,0.45,0.29,0.71,0.29c0.25,0,0.51-0.101,0.71-0.3 c0.39-0.391,0.38-1.021-0.01-1.41C6.458,34.859,5.828,34.859,5.438,35.25z"/> <path d="M25.158,15.37c-0.39,0.399-0.39,1.029,0,1.42c0.2,0.189,0.45,0.29,0.7,0.29c0.26,0,0.52-0.101,0.72-0.3 c0.38-0.391,0.38-1.021-0.01-1.41C26.178,14.979,25.539,14.979,25.158,15.37z"/> <path d="M11.008,40.91c-0.39,0.39-0.39,1.02,0,1.409c0.2,0.2,0.45,0.29,0.71,0.29c0.25,0,0.51-0.09,0.71-0.29 c0.39-0.39,0.39-1.02,0-1.409C12.028,40.52,11.398,40.52,11.008,40.91z"/> <path d="M13.838,43.74c-0.39,0.39-0.39,1.02,0,1.409c0.2,0.2,0.45,0.29,0.71,0.29c0.25,0,0.51-0.09,0.7-0.29 c0.39-0.39,0.39-1.02,0-1.409C14.858,43.35,14.229,43.35,13.838,43.74z"/> <path d="M11.068,29.569c-0.39,0.4-0.38,1.03,0.01,1.421c0.19,0.189,0.45,0.29,0.7,0.29c0.26,0,0.52-0.101,0.71-0.301 c0.39-0.39,0.39-1.02-0.01-1.41C12.088,29.18,11.458,29.18,11.068,29.569z"/> <path d="M30.708,46.55c-0.39,0.39-0.38,1.03,0.02,1.41c0.19,0.189,0.44,0.28,0.69,0.28c0.26,0,0.52-0.101,0.72-0.301 c0.38-0.39,0.38-1.029-0.02-1.409C31.729,46.14,31.088,46.149,30.708,46.55z"/> <path d="M44.658,32.22c-0.39,0.39-0.38,1.03,0.02,1.41c0.19,0.189,0.44,0.29,0.7,0.29c0.26,0,0.52-0.101,0.71-0.3 c0.39-0.4,0.38-1.04-0.02-1.42C45.678,31.81,45.048,31.819,44.658,32.22z"/> <path d="M39.078,37.95c-0.39,0.399-0.38,1.029,0.02,1.409c0.19,0.19,0.44,0.29,0.69,0.29c0.26,0,0.52-0.1,0.72-0.3 c0.39-0.399,0.38-1.04-0.02-1.42C40.098,37.54,39.458,37.55,39.078,37.95z"/> <path d="M41.868,35.09c-0.39,0.39-0.38,1.02,0.02,1.41c0.19,0.189,0.44,0.28,0.69,0.28c0.27,0,0.53-0.101,0.72-0.301 c0.39-0.399,0.38-1.029-0.02-1.41C42.888,34.68,42.249,34.689,41.868,35.09z"/> <path d="M47.448,29.35c-0.39,0.4-0.38,1.03,0.02,1.42c0.19,0.19,0.44,0.28,0.7,0.28c0.26,0,0.52-0.1,0.71-0.3 c0.39-0.4,0.38-1.03-0.02-1.42C48.468,28.95,47.828,28.96,47.448,29.35z"/> <circle cx="50.499" cy="19" r="1"/> <path d="M27.918,49.41c-0.39,0.399-0.38,1.029,0.02,1.42c0.19,0.189,0.44,0.279,0.69,0.279c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.399,0.38-1.029-0.02-1.41C28.928,49.01,28.298,49.02,27.918,49.41z"/> <circle cx="50.499" cy="27" r="1"/> <circle cx="50.499" cy="23" r="1"/> <path d="M33.499,43.68c-0.39,0.4-0.38,1.03,0.02,1.42c0.19,0.19,0.44,0.28,0.69,0.28c0.26,0,0.52-0.1,0.72-0.3 c0.39-0.4,0.38-1.03-0.02-1.42C34.508,43.28,33.878,43.29,33.499,43.68z"/> <path d="M39.918,9c0-0.55-0.45-1-1-1c-0.56,0-1,0.45-1,1s0.44,1,1,1C39.468,10,39.918,9.55,39.918,9z"/> <path d="M27.968,12.53c-0.39,0.39-0.38,1.029,0.01,1.42c0.19,0.189,0.45,0.29,0.7,0.29c0.26,0,0.52-0.101,0.71-0.301 c0.39-0.39,0.39-1.02,0-1.409C28.988,12.14,28.358,12.14,27.968,12.53z"/> <path d="M30.789,9.689c-0.39,0.4-0.39,1.03,0.01,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.51-0.1,0.71-0.3 c0.39-0.39,0.39-1.02-0.01-1.41C31.809,9.3,31.178,9.3,30.789,9.689z"/> <path d="M34.918,8c-0.56,0-1,0.45-1,1s0.44,1,1,1c0.55,0,1-0.45,1-1S35.468,8,34.918,8z"/> <path d="M36.289,40.819c-0.39,0.391-0.38,1.03,0.02,1.41c0.19,0.19,0.44,0.28,0.69,0.28c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.391,0.38-1.03-0.02-1.41C37.309,40.41,36.668,40.42,36.289,40.819z"/> <path d="M59.206,0.293c-0.391-0.391-1.023-0.391-1.414,0L54.084,4H30.802L1.532,33.511c-0.667,0.666-1.034,1.553-1.034,2.495 s0.367,1.829,1.034,2.495l20.466,20.466c0.687,0.687,1.588,1.03,2.491,1.03c0.906,0,1.814-0.346,2.508-1.04l28.501-29.271V5.414 l3.707-3.707C59.596,1.316,59.596,0.684,59.206,0.293z M53.499,28.874L25.574,57.553c-0.595,0.596-1.565,0.596-2.162,0 L2.946,37.087c-0.289-0.289-0.448-0.673-0.448-1.081s0.159-0.792,0.451-1.084L31.635,6h20.45l-4.833,4.833 C46.461,10.309,45.516,10,44.499,10c-2.757,0-5,2.243-5,5s2.243,5,5,5s5-2.243,5-5c0-1.017-0.309-1.962-0.833-2.753l4.833-4.833 V28.874z M47.499,15c0,1.654-1.346,3-3,3s-3-1.346-3-3s1.346-3,3-3c0.462,0,0.894,0.114,1.285,0.301l-1.992,1.992 c-0.391,0.391-0.391,1.023,0,1.414C43.987,15.902,44.243,16,44.499,16s0.512-0.098,0.707-0.293l1.992-1.992 C47.385,14.106,47.499,14.538,47.499,15z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Price</div><div class="gt-inner"><ul><div class="gt-price"><span></span>€415 - €595</div></ul></div></div></li><li class="gt-organizers"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 60 60" xml:space="preserve"> <path d="M48.014,42.889l-9.553-4.776C37.56,37.662,37,36.756,37,35.748v-3.381c0.229-0.28,0.47-0.599,0.719-0.951 c1.239-1.75,2.232-3.698,2.954-5.799C42.084,24.97,43,23.575,43,22v-4c0-0.963-0.36-1.896-1-2.625v-5.319 c0.056-0.55,0.276-3.824-2.092-6.525C37.854,1.188,34.521,0,30,0s-7.854,1.188-9.908,3.53C17.724,6.231,17.944,9.506,18,10.056 v5.319c-0.64,0.729-1,1.662-1,2.625v4c0,1.217,0.553,2.352,1.497,3.109c0.916,3.627,2.833,6.36,3.503,7.237v3.309 c0,0.968-0.528,1.856-1.377,2.32l-8.921,4.866C8.801,44.424,7,47.458,7,50.762V54c0,4.746,15.045,6,23,6s23-1.254,23-6v-3.043 C53,47.519,51.089,44.427,48.014,42.889z M51,54c0,1.357-7.412,4-21,4S9,55.357,9,54v-3.238c0-2.571,1.402-4.934,3.659-6.164 l8.921-4.866C23.073,38.917,24,37.354,24,35.655v-4.019l-0.233-0.278c-0.024-0.029-2.475-2.994-3.41-7.065l-0.091-0.396l-0.341-0.22 C19.346,23.303,19,22.676,19,22v-4c0-0.561,0.238-1.084,0.67-1.475L20,16.228V10l-0.009-0.131c-0.003-0.027-0.343-2.799,1.605-5.021 C23.253,2.958,26.081,2,30,2c3.905,0,6.727,0.951,8.386,2.828c1.947,2.201,1.625,5.017,1.623,5.041L40,16.228l0.33,0.298 C40.762,16.916,41,17.439,41,18v4c0,0.873-0.572,1.637-1.422,1.899l-0.498,0.153l-0.16,0.495c-0.669,2.081-1.622,4.003-2.834,5.713 c-0.297,0.421-0.586,0.794-0.837,1.079L35,31.623v4.125c0,1.77,0.983,3.361,2.566,4.153l9.553,4.776 C49.513,45.874,51,48.28,51,50.957V54z"/> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Organizer</div><div class="gt-inner"><ul><li><a href="https://www.uventia.com/event-organizer/uventia/?post_type=event">Uventia</a></li></ul></div></div></li><li class="gt-categories"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 60 60" xml:space="preserve"> <path d="M57.49,21.5H54v-6.268c0-1.507-1.226-2.732-2.732-2.732H26.515l-5-7H2.732C1.226,5.5,0,6.726,0,8.232v43.687l0.006,0 c-0.005,0.563,0.17,1.114,0.522,1.575C1.018,54.134,1.76,54.5,2.565,54.5h44.759c1.156,0,2.174-0.779,2.45-1.813L60,24.649v-0.177 C60,22.75,58.944,21.5,57.49,21.5z M2,8.232C2,7.828,2.329,7.5,2.732,7.5h17.753l5,7h25.782c0.404,0,0.732,0.328,0.732,0.732V21.5 H12.731c-0.144,0-0.287,0.012-0.426,0.036c-0.973,0.163-1.782,0.873-2.023,1.776L2,45.899V8.232z M47.869,52.083 c-0.066,0.245-0.291,0.417-0.545,0.417H2.565c-0.243,0-0.385-0.139-0.448-0.222c-0.063-0.082-0.16-0.256-0.123-0.408l10.191-27.953 c0.066-0.245,0.291-0.417,0.545-0.417H54h3.49c0.38,0,0.477,0.546,0.502,0.819L47.869,52.083z"/> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Category</div><div class="gt-inner"><ul><li><a 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aria-controls="gt-event-tab-2" aria-selected="true">SPEAKERS</a></li><li><a data-toggle="tab" href="#gt-event-tab-3" data-gt-type="content" role="tab" aria-controls="gt-event-tab-3" aria-selected="true">AGENDA</a></li></ul><div class="tab-content"><div class="tab-pane fade active show" id="gt-event-tab-1" data-gt-type="content" role="tabpanel" aria-labelledby="nav-gt-event-tab-1-tab"><div class="gt-content"><p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p style="padding-left: 40px"><strong>CONFERENCE <span class="has-inline-color has-luminous-vivid-amber-color"><span style="color: #feba26">OVERVIEW</span><br /></span></strong></p> <p>Impurities may have a negative effect on the efficacy, safety, and quality of pharmaceutical components and products. The successful development and manufacturing of novel medications now depend heavily on the assessment of the impurity profiles as well as the management and monitoring of those. The diligent identification of nitrosamines and other genotoxic contaminants should be established at every step of drug development in order to comply with growing regulatory requirements and prevent costly recalls.</p> <p>Our online meeting, which we organized in collaboration with industry professionals, aimed to showcase and discuss different perspectives on addressing the challenges caused by mutagenic impurities. We will go over drug impurity profiling techniques that follow regulatory guidelines, as well as useful tips for adhering to recent updates to ICH M7 and Q3D, new nitrosamine regulations, nitrosamine impurities determination and calculation, risk assessment for genotoxic impurities, analytical challenges, development of acceptance criteria and most recent developments in elemental impurity assessment.</p> <p>Reserve your spot for this informative webinar so that you can leave with new ideas and best practices for managing genotoxic and elemental impurities.</p> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p style="padding-left: 40px"><strong>WE WILL <span style="color: #feba26">BE FOCUSING ON</span></strong></p> <ul> <li>N-nitrosamines and mutagenic impurities – drug substance quality considerations and in vivo fate of Nitrosamines</li> <li>Emerging focus for drug product assessment for N-nitrosamines – perspective on quality, safety and regulatory environment</li> <li>Toxicological risk assessment of Nitrosamines – challenges and perspectives</li> <li>Reactivities of N-nitrosamines against Common Reagents and Reaction Conditions: Understanding the potential for Purge</li> <li>Setting limits for NDSRIs</li> <li>Nitrite scavengers as excipients for inhibition of N-nitrosamine formation in drug products</li> <li>Addressing NDSRI Risks</li> <li>Using relative potency of mutation and cancer data, to derive AI’s for Nitrosamines</li> <li>Nitrites: the elephant in the room</li> <li>Toxicological risk assessment of genotoxic impurities: derivation and justification of safe limits</li> <li>Safety assessment of non-genotoxic and genotoxic/carcinogenic extractables and leachables</li> <li>Validation of the Enhanced Ames Test for Nitrosamines</li> </ul> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p style="padding-left: 40px"><strong>WHO IS <span style="color: #feba26">IT FOR?</span></strong></p> <p><strong>CxO, VP, Directors, Heads, Managers of</strong></p> <ul> <li>Genotoxic Impurities/ GTIs/ Genotoxins/ Elemental Impurities</li> <li>Genotoxicity/ Mutagenicity</li> <li>Carcinogenicity/ Carcinogens</li> <li>Genetic Toxicology/ Chemical Toxicology/ Computational Toxicology</li> <li>Analytical Chemistry/ Analytical Development/ Analytical Science</li> <li>Drug Discovery/ Drug Development/ Drug Substance</li> <li>Drug Safety/ Compound Safety</li> <li>Process Chemistry/ Process Development</li> <li>Product Characterisation/ Risk Assessment</li> <li>Pharmacokinetics/ Metabolism</li> <li>Extractables & Leachables</li> <li>API Development/ Degradation Products</li> <li>LC-MS/ Mass Spectrometry</li> <li>Good Laboratory Practice (GLP)/ Good Manufacturing Practice (GMP)</li> <li>Regulatory Affairs & Compliance</li> </ul> </div> </div> <div class="vc_empty_space" style="height: 32px"><span class="vc_empty_space_inner"></span></div></div></div></div></div><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_single_image wpb_content_element vc_align_center wpb_content_element"> <figure class="wpb_wrapper vc_figure"> <div class="vc_single_image-wrapper vc_box_border_grey"><img width="300" height="300" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="vc_single_image-img attachment-medium gt-lazy-load" alt="" title="" decoding="async" data-src="https://www.uventia.com/wp-content/uploads/2024/10/Agendas-4GTI-300x300.png?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2024/10/Agendas-4GTI-300x300.png 300w, https://www.uventia.com/wp-content/uploads/2024/10/Agendas-4GTI-150x150.png 150w, https://www.uventia.com/wp-content/uploads/2024/10/Agendas-4GTI-350x350.png 350w, https://www.uventia.com/wp-content/uploads/2024/10/Agendas-4GTI-85x85.png 85w, https://www.uventia.com/wp-content/uploads/2024/10/Agendas-4GTI-100x100.png 100w, https://www.uventia.com/wp-content/uploads/2024/10/Agendas-4GTI.png 500w" data-sizes="(max-width: 300px) 100vw, 300px" /></div> </figure> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h3>[<span style="color: #ffbb00">Agenda</span>] 4<sup>th</sup> Annual Genotoxic Impurities Summit: Nitrosamines & Beyond 2024</h3> 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vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"><div class="vc_tta-container" data-vc-action="collapse"><div class="vc_general vc_tta vc_tta-tabs vc_tta-color-grey vc_tta-style-modern vc_tta-shape-rounded vc_tta-spacing-1 vc_tta-tabs-position-top vc_tta-controls-align-left"><div class="vc_tta-tabs-container"><ul class="vc_tta-tabs-list"><li class="vc_tta-tab vc_active" data-vc-tab><a href="#4-gti-1" data-vc-tabs data-vc-container=".vc_tta"><i class="vc_tta-icon vc-oi vc-oi-calendar"></i><span class="vc_tta-title-text">ATTENDEES IN 2023</span></a></li><li class="vc_tta-tab" data-vc-tab><a href="#4-gti-2" data-vc-tabs data-vc-container=".vc_tta"><i class="vc_tta-icon vc-oi vc-oi-calendar"></i><span class="vc_tta-title-text">ATTENDEES IN 2022</span></a></li></ul></div><div class="vc_tta-panels-container"><div class="vc_tta-panels"><div class="vc_tta-panel vc_active" id="4-gti-1" data-vc-content=".vc_tta-panel-body"><div class="vc_tta-panel-heading"><h4 class="vc_tta-panel-title"><a href="#4-gti-1" data-vc-accordion data-vc-container=".vc_tta-container"><i class="vc_tta-icon vc-oi vc-oi-calendar"></i><span class="vc_tta-title-text">ATTENDEES IN 2023</span></a></h4></div><div class="vc_tta-panel-body"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p>● A&M STABTEST GmbH ● Abbott ● ACG Europe d.o.o. ● Adamed Pharma S.A. ● Advanz Pharma ● AGES-MEA ● ALK-Abelló S.A. ● American Regent ● AMSlab ● Angelini Pharma S.p.A. ● APIs & NCE Manufacturing LeadAC Immune SA ● Aptuit an Evotec Company ● ARLANXEO Netherlands B.V ● Arrotex Pharmaceuticals Pty Ltd ● Astellas Pharma Europe BV ● Astellas Pharma Inc. ● AstraZeneca ● BD Technologies ● Boehringer Ingelheim Pharma GmbH & Co. KG ● Charles River Laboratories ● Chugai Pharmaceutical Co., Ltd. ● Croma-Pharma GmbH ● CSL Behring ● Dottikon Exclusive Synthesis AG ● EDQM, Council of Europe ● Excella GmbH & Co. KG ● FARMAK, a.s. ● Fermion Oy ● Fresenius Kabi ● Fresenius Kabi Deutschland GmbH ● FUJIFILM Toyama Chemical ● Gentronix Ltd ● Grunenthal Ecuatoriana Cia. Ltda. ● GSK ● Haleon ● Health and Environmental Sciences Institute (HESI) ● Hemofarm AD ● Hemomont d.o.o. ● Idorsia ● Insight Exposure and Risk Sciences ● Intertek ● Intertek Melbourn ● Intox Private Limited ● Intuitive Fluorescence Imaging, LLC ● Johnson&Johnson ● Konya Food and Agriculture University ● Krka d. d., Novo mesto ● L.Molteni & C. dei F.lli Alitti SpA ● LabAnalysis S.r.l. ● Laboratoires MAYOLY SPINDLER ● Labtim ADRIA d.o.o. ● LangAllan CMC Regulatory Solutions Ltd ● Lek Pharmaceuticals d.d. ● Lhasa Limited ● Lundbeck ● Luye Pharma AG ● Merck Healthcare KGaA ● Midas Pharma GmbH ● MultiCASE Inc ● National Institute of Health Sciences ● Norwich Pharmaceuticals ● Novartis ● Olon S.p.A. ● Orion Pharma ● Pfizer ● Pharmaceutical firm Darnitsa ● Polpharma ● Preclintox Services, LLC ● ProBioGen AG ● Rontis Hellas ● S-IN Soluzioni Informatiche ● Safetree Consulting e.U. ● Sanofi ● SEQENS ● Solvias AG ● State Agency of Medicines ● Swansea University ● Swissmedic ● Takeda ● Takeda Pharmaceuticals ● Tallinn University of Technology ● Teva Pharmaceutical Industries Ltd. ● TEVA Pharmaceutical Works Ltd ● Teva Pharmaceuticals ● ToxMinds BVBA ● UCB ● Vertex Pharmaceuticals ● Viatris ● Waters ● Waters Corporation ● Zakłady Farmaceutyczne Polpharma ● Zentiva Group, a.s.</p> </div> </div> </div></div><div class="vc_tta-panel" id="4-gti-2" data-vc-content=".vc_tta-panel-body"><div class="vc_tta-panel-heading"><h4 class="vc_tta-panel-title"><a href="#4-gti-2" data-vc-accordion data-vc-container=".vc_tta-container"><i class="vc_tta-icon vc-oi vc-oi-calendar"></i><span class="vc_tta-title-text">ATTENDEES IN 2022</span></a></h4></div><div class="vc_tta-panel-body"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p>● Adamed Pharma ● Lundbeck ● Astellas Pharma Europe B.V. ● Sanofi ● Dr. Reddy’s Laboratories Limited ● Airnov Healthcare Packaging ● Egis Pharmaceuticals Plc. ● Waters Corporation ● Teva Pharmaceutical ● Synthon ● Synthon B.V. ● Polpharma ● Silence Therapeutics ● Menarini Ricerche ● Polpharma SA ● Krka ● Teva Pharmaceutical Industries Ltd ● Teva Active Pharmaceutical Ingredients ● Neurocrine Biosciences ● JSC Olainfarm ● Bibra toxicology advice & consulting Ltd ● Berlin-Chemie AG ● Janssen Pharmaceutica ● Jazz Pharmaceuticals ● Pliva Hrvatska d.o.o. ● Dr. Anika Schroeter e.U. ● Eurofins PSS ● Angelini Pharma S.p.A. ● Food and Drug Administration ● Astellas Pharma Europe ● Saneca Pharmaceuticals ● Teva Israel Ltd ● Arrotex Pty Ltd ● Merck Healthcare KGaA ● Boehringer Ingelheim Pharma GmbH & Co. KG ● Bracco Imaging SpA ● Perrigo ● Chiesi Farmaceutici SpA ● Advanz Pharma ● Midas Pharma GmbH ● Aptuit an Evotec Company ● Hikma Pharmaceuticals ● Aptuit (Verona) S.r.L., An Evotec Company ● Adamed Pharma S.A. ● fagg-afmps ● World Health Organization (WHO) ● Curia Spain S.A.U. ● Swissmedic ● Albhades ● Finnish Medicines Agency ● Selvita S.A. ● Fresenius Medical Care Deutschland GmbH ● Fresenius Kabi ● IFF ● Teva Ni Ltd ● Bayer AG ● FUJIFILM Toyama Chemical Co., Ltd. ● INEOS Oxide ● Affygility Solutions ● Laboratorium Zdrochem sp. z o.o. ● Zentiva, k.s. ● Janssen ● Bachem AG ● BD ● Jagiellonian Center of Innovation ● Sanofi Chimie ● Venn Life Sciences ● Merck KGaA, Darmstadt, Germany ● Teva Gyogyszergyar Zrt. ● Drug Development Solutions ● Senior Consultant ● Lonza AG ● Alliance Pharmaceuticals Ltd ● Minakem ● B. Braun Medical, S.A.U. ● Smith + Nephew ● Haleon ● LabExperts Sp. z o.o. ● Technologie Servier ● Ipca Laboratories Ltd. ● Recipharm Pharmaservices Pvt Ltd ● ANTIBIOTICE SA ● Pharmaceutical Firm Darnitsa ● Bausch Health ● Idorsia ● Pfizer ● Avivia ● Altox ● West Pharmaceutical Services ● GSK ● Novartis ● Teva Pharmaceuticals ● Lhasa Limited ● Gilead Sciences Inc. ● Amgen Inc. ● Sandoz ● Instem, Inc. ● Generapharm ● Pfizer Global R&D ● United States Pharmacopeia</p> </div> </div> </div></div></div></div></div></div><div class="vc_empty_space" style="height: 32px"><span class="vc_empty_space_inner"></span></div><div class="gt-button gt-style-2 gt-align-center gt-inline-false gt-margin-false"><a href="https://www.uventia.com/registration-4th-annual-genotoxic-impurities-summit-nitrosamines-beyond-2024/" target="_parent"><i class="fa-regular fa-pen-to-square"></i><span>REGISTER NOW</span></a></div></div></div></div></div></p> </div></div><div class="tab-pane fade" id="gt-event-tab-2" 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data-srcset="https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_.jpg 350w, https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div class="gt-content"><a href="https://www.uventia.com/speaker/malcolm-ross/"></a><div class="gt-name"><a href="https://www.uventia.com/speaker/malcolm-ross/">Malcolm Ross</a></div><div class="gt-profession">Consultant</div><div class="gt-company">Generapharm</div><div class="gt-social-links"><ul class="gt-social-links"><li><a href="https://www.linkedin.com/in/malcolm-ross-00b5b51/" target="_blank"><i class="fa-brands fa-linkedin-in"></i></a></li></ul></div></div></div></div></div><div class="gt-col"><div class="gt-inner"><div class="gt-speaker gt-style-4"><div class="gt-image"><a href="https://www.uventia.com/speaker/mike-urquhart/"><img width="350" height="350" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-thumbnail size-eventchamp-thumbnail gt-lazy-load" alt="Mike Urquhart" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart.jpg 350w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-100x100.jpg 100w" data-sizes="auto, (max-width: 350px) 100vw, 350px" /></a></div><div 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4</a></li><li><a data-toggle="tab" href="#gt-event-schedule-2" role="tab" aria-controls="gt-event-schedule-2" aria-selected="true">December 5</a></li></ul><div class="gt-dropdown"><div class="tab-content"><div class="tab-pane fade active show" id="gt-event-schedule-1" role="tabpanel" aria-labelledby="nav-gt-event-schedule-1-tab"><div class="gt-panel-group" id="event-schedule-accardion-441144" role="tablist" aria-multiselectable="true"><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-891679"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-891679" aria-expanded="true" aria-controls="event-schedule-collapse-891679"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">11:50 - 12:00</div><div class="gt-title">✍ REGISTRATION</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-891679" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-891679"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-982725"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-982725" aria-expanded="true" aria-controls="event-schedule-collapse-982725"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">12:10</div><div class="gt-title">Emerging focus for Drug Product Assessment for N-Nitrosamines – Perspective on Quality, Safety and Regulatory Environment</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-982725" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-982725"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span>Emergence of new guidance to establish AI and further understanding for NDSRI formation in DP published.</p> <p><span style="color: #ff9900">◆  </span>Changes to the DP risk assessment process as a consequence.</p> <p><span style="color: #ff9900">◆  </span>Actions to take when an NDSRI is realised – includes discussion of using metabolism ID studies to help build understanding (weight of evidence) for the N-nitrosamine toxicity.</p> <p><span style="color: #ff9900">◆  </span>High level overview of GSK experiences of remediation in DS and DP.</p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/12/GSK-130x60.png?x85084" alt="GSK" width="130" height="60" /><span class="su-custom-gallery-title">GSK</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="https://www.gsk.com/" target="_blank" rel="noopener">GSK</a>, UK</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/mike-urquhart/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Mike Urquhart" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2022/08/Mike-Urquhart.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Mike Urquhart</div><div class="gt-profession">Scientific Director</div><div class="gt-company">GSK</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-972999"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-972999" aria-expanded="true" aria-controls="event-schedule-collapse-972999"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">13:05</div><div class="gt-title">N-Nitrosamines and Mutagenic Impurities – Drug Substance Quality Considerations and In Vivo Fate of Nitrosamines</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-972999" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-972999"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span>EFPIA Drug Substance N-nitrosamine risk assessment workflow version 3: Design thoughts, structure of the workflow and highlights of recent key scientific advances which underpin the risk assessments.</p> <p><span style="color: #ff9900">◆  </span>A chemistry view of the in-vivo fate of nitrosamines: description of a kinetic model for assessing potential nitrosamine carcinogenicity. Fundamental mechanistic considerations which allow to rationalise the observed high diversity of carcinogenic potencies.</p> <ol> <li>CPCA Cat 1 and Cat 2 alternative limit proposal for nitrosamines with a MW > 200</li> </ol> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2022/08/Pfizer-130x60.png?x85084" alt="Pfizer" width="130" height="60" /><span class="su-custom-gallery-title">Pfizer</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="https://www.pfizer.com/" target="_blank" rel="noopener">Pfizer</a>, UK</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/olivier-dirat/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Olivier Dirat" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2024/06/Olivier-Dirat-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2024/06/Olivier-Dirat-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2024/06/Olivier-Dirat-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2024/06/Olivier-Dirat-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2024/06/Olivier-Dirat-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2024/06/Olivier-Dirat.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Olivier Dirat</div><div class="gt-profession">Senior Director – Global Regulatory Sciences</div><div class="gt-company">Pfizer</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-701559"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-701559" aria-expanded="true" aria-controls="event-schedule-collapse-701559"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">13:50 - 14:10</div><div class="gt-title">☕️ BREAK</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-701559" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-701559"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-542267"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-542267" aria-expanded="true" aria-controls="event-schedule-collapse-542267"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">14:10</div><div class="gt-title">Toxicological Risk Assessment of Nitrosamines – Challenges and Perspectives</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-542267" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-542267"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span>Overview of toxicological risk assessment of nitrosamines.</p> <p><span style="color: #ff9900">◆  </span>Comparison between agency- and literature-published acceptable intake values.</p> <p><span style="color: #ff9900">◆  </span>Challenges with the current state of affairs and future perspectives.</p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/12/Baxter-Healthcare-130x60.png?x85084" alt="Baxter-Healthcare" width="130" height="60" /><span class="su-custom-gallery-title">Baxter-Healthcare</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="https://www.baxter.com/" target="_blank" rel="noopener">Baxter</a>, BE</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/crystal-dsilva/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Crystal DSilva" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2024/05/Crystal-DSilva-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2024/05/Crystal-DSilva-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2024/05/Crystal-DSilva-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2024/05/Crystal-DSilva-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2024/05/Crystal-DSilva-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2024/05/Crystal-DSilva.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Crystal DSilva</div><div class="gt-profession">Associate Director – Preclinical Toxicology</div><div class="gt-company">Baxter</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-551541"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-551541" aria-expanded="true" aria-controls="event-schedule-collapse-551541"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">14:50</div><div class="gt-title">Reactivities of N-nitrosamines against Common Reagents and Reaction Conditions: Understanding the potential for Purge</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-551541" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-551541"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span></p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/08/Lhasa-Limited-130x60.png?x85084" alt="Lhasa-Limited" width="130" height="60" /><span class="su-custom-gallery-title">Lhasa-Limited</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="https://www.lhasalimited.org/" target="_blank" rel="noopener">Lhasa Limited</a>, UK</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/michael-burns/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Michael Burns" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2021/08/Michael-Burns.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Michael Burns</div><div class="gt-profession">Principal Research Scientist</div><div class="gt-company">Lhasa Limited</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-274798"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-274798" aria-expanded="true" aria-controls="event-schedule-collapse-274798"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">15:20 - 16:00</div><div class="gt-title">☕️ BREAK</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-274798" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-274798"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-327730"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-327730" aria-expanded="true" aria-controls="event-schedule-collapse-327730"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">16:00</div><div class="gt-title">Setting limits for NDSRIs</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-327730" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-327730"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span>Methods for setting acceptable intakes (AIs) for NDSRIs.</p> <p><span style="color: #ff9900">◆  </span>Good read across vs bad read across.</p> <p><span style="color: #ff9900">◆  </span>Use of in vivo mutagenicity (negative and positive) to set AIs for NDSRIs.</p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/08/Nudelman-ChemTox-Consulting-130x60.png?x85084" alt="Nudelman-ChemTox-Consulting" width="130" height="60" /><span class="su-custom-gallery-title">Nudelman-ChemTox-Consulting</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="#" target="_blank" rel="noopener">Nudelman ChemTox Consulting</a>, IL</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/raphael-nudelman/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Raphael Nudelman" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2021/08/Raphael-Nudelman.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Raphael Nudelman</div><div class="gt-profession">Chemical Toxicologist</div><div class="gt-company">Nudelman ChemTox Consulting</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-421344"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-421344" aria-expanded="true" aria-controls="event-schedule-collapse-421344"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">16:40</div><div class="gt-title">[RESERVED] for Aptar CSP Technologies</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-421344" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-421344"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-231746"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-231746" aria-expanded="true" aria-controls="event-schedule-collapse-231746"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">17:20</div><div class="gt-title">Addressing NDSRI Risks</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-231746" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-231746"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span>Recent HA focus on NDSRI risk has required us to reassess the end to end portfolio to address any concerns from the nitrosamine impurities. </p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/03/Bristol-Myers-Squibb-130x60.png?x85084" alt="Bristol-Myers-Squibb" width="130" height="60" /><span class="su-custom-gallery-title">Bristol-Myers-Squibb</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="https://www.bms.com/" target="_blank" rel="noopener">Bristol Myers Squibb</a>, USA</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/rodney-parsons/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Rodney Parsons" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2024/10/Rodney-Parsons-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2024/10/Rodney-Parsons-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2024/10/Rodney-Parsons-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2024/10/Rodney-Parsons-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2024/10/Rodney-Parsons-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2024/10/Rodney-Parsons.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Rodney Parsons</div><div class="gt-profession">Executive Director</div><div class="gt-company">Bristol-Myers Squibb</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-124818"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-124818" aria-expanded="true" aria-controls="event-schedule-collapse-124818"><div class="gt-inner"><div class="gt-date">December 4, 2024</div><div class="gt-time">17:50 - 18:00</div><div class="gt-title">🎤 Chairman’s closing remarks and end of DAY ONE</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-124818" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-124818"><div class="gt-panel-body"></div></div></div></div></div><div class="tab-pane fade" id="gt-event-schedule-2" role="tabpanel" aria-labelledby="nav-gt-event-schedule-2-tab"><div class="gt-panel-group" id="event-schedule-accardion-441144" role="tablist" aria-multiselectable="true"><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-233316"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-233316" aria-expanded="true" aria-controls="event-schedule-collapse-233316"><div class="gt-inner"><div class="gt-date">December 5, 2024</div><div class="gt-time">11:50 - 12:00</div><div class="gt-title">✍ REGISTRATION</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-233316" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-233316"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-489123"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-489123" aria-expanded="true" aria-controls="event-schedule-collapse-489123"><div class="gt-inner"><div class="gt-date">December 5, 2024</div><div class="gt-time">12:10</div><div class="gt-title">Using relative potency of mutation and cancer data, to derive AI’s for nitrosamines</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-489123" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-489123"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span>Using benchmark dose (BMD) analysis to compare potencies.</p> <p><span style="color: #ff9900">◆  </span>Relative potency between mutation and cancer for different nitrosamines.</p> <p><span style="color: #ff9900">◆  </span>Using relative potency to calculate acceptable intakes from in vivo mutation data.</p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2023/09/Swansea-University-130x60.png?x85084" alt="Swansea-University" width="130" height="60" /><span class="su-custom-gallery-title">Swansea-University</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="https://www.swansea.ac.uk/medicine-health-life-science/facilities/institute-of-life-science/" target="_blank" rel="noopener">Swansea University Institute Of Life Science</a>, UK</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/george-johnson/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="George Johnson" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/09/George-Johnson.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">George Johnson</div><div class="gt-profession">Associate Professor</div><div class="gt-company">Swansea University</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-69067"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-69067" aria-expanded="true" aria-controls="event-schedule-collapse-69067"><div class="gt-inner"><div class="gt-date">December 5, 2024</div><div class="gt-time">12:50</div><div class="gt-title">Nitrites: The elephant in the room</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-69067" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-69067"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span>The role of nitrites in excipients in the formation of NDSRIs in drug products.</p> <p><span style="color: #ff9900">◆  </span>The reasons behind the presence of nitrites in excipients and some reasons for the very high variability of reported levels.</p> <p><span style="color: #ff9900">◆  </span>Processing air as a source of nitrite and nitrosation.</p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2022/08/Generapharm-130x60.png?x85084" alt="Generapharm" width="130" height="60" /><span class="su-custom-gallery-title">Generapharm</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="http://generapharm.eu/" target="_blank" rel="noopener">Generapharm Training and Consultancy</a>, CH</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/malcolm-ross/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Malcolm Ross" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2022/08/Malcolm-Ross_.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Malcolm Ross</div><div class="gt-profession">Consultant</div><div class="gt-company">Generapharm</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-459296"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-459296" aria-expanded="true" aria-controls="event-schedule-collapse-459296"><div class="gt-inner"><div class="gt-date">December 5, 2024</div><div class="gt-time">13:20 - 13:40</div><div class="gt-title">☕️ BREAK</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-459296" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-459296"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-382062"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-382062" aria-expanded="true" aria-controls="event-schedule-collapse-382062"><div class="gt-inner"><div class="gt-date">December 5, 2024</div><div class="gt-time">13:40</div><div class="gt-title">Toxicological Risk Assessment of Genotoxic Impurities: Derivation and Justification of Safe Limits</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-382062" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-382062"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span>Regulatory guidelines and position papers.</p> <p><span style="color: #ff9900">◆  </span>Toxicological risk assessment of genotoxic impurities of medical devices.</p> <p><span style="color: #ff9900">◆  </span>Parallels with toxicological risk assessment of genotoxic impurities of pharmaceuticals.</p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2024/07/B.-Braun-Melsungen-130x60.png?x85084" alt="B.-Braun-Melsungen" width="130" height="60" /><span class="su-custom-gallery-title">B.-Braun-Melsungen</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="https://www.bbraun.com/" target="_blank" rel="noopener">B. Braun Melsungen AG</a>, DE</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/alina-martirosyan/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Alina Martirosyan" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2024/07/Alina-Martirosyan-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2024/07/Alina-Martirosyan-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2024/07/Alina-Martirosyan-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2024/07/Alina-Martirosyan-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2024/07/Alina-Martirosyan-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2024/07/Alina-Martirosyan.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Alina Martirosyan</div><div class="gt-profession">Sr. Scientific Manager Toxicology</div><div class="gt-company">B. Braun Melsungen AG</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-888947"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-888947" aria-expanded="true" aria-controls="event-schedule-collapse-888947"><div class="gt-inner"><div class="gt-date">December 5, 2024</div><div class="gt-time">14:20</div><div class="gt-title">Chemical Characterization and Toxicological Risk Assessment of Genotoxic Impurities in Medical Devices</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-888947" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-888947"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span>Establishment of the Analytical Evaluation Threshold (AET) for an implantable, absorbable medical device.</p> <p><span style="color: #ff9900">◆  </span>Conducting in silico assessments of potential genotoxic impurities.</p> <p><span style="color: #ff9900">◆  </span>Addressing recent regulatory developments and navigating associated challenges.</p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/09/croma_est1976-130x60.png?x85084" alt="croma_est1976" width="130" height="60" /><span class="su-custom-gallery-title">croma_est1976</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="https://www.cromapharma.com/" target="_blank" rel="noopener">Croma-Pharma GmbH</a>, AT</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/patrick-reichl/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Patrick Reichl" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2021/09/Patrick-Reichl.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Patrick Reichl</div><div class="gt-profession">Toxicology Lead</div><div class="gt-company">Croma-Pharma GmbH</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-503798"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-503798" aria-expanded="true" aria-controls="event-schedule-collapse-503798"><div class="gt-inner"><div class="gt-date">December 5, 2024</div><div class="gt-time">14:50 - 15:10</div><div class="gt-title">☕️ BREAK</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-503798" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-503798"><div class="gt-panel-body"></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-237029"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-237029" aria-expanded="true" aria-controls="event-schedule-collapse-237029"><div class="gt-inner"><div class="gt-date">December 5, 2024</div><div class="gt-time">15:10</div><div class="gt-title">Safety assessment of non-genotoxic and genotoxic/carcinogenic Extractables and Leachables</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-237029" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-237029"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆  </span>Regulatory environment concerning E&L.</p> <p><span style="color: #ff9900">◆  </span>E&L safety assessment - Similarities and differences to assessment of drug substance impurities.</p> <p><span style="color: #ff9900">◆  </span>Approaches for hazard assessment and safety threshold derivation.</p> <p><span style="color: #ff9900">◆  </span>Cohort of concern impurities observed as E&L.</p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2021/09/Safetree-Consulting-130x60.png?x85084" alt="Safetree-Consulting" width="130" height="60" /><span class="su-custom-gallery-title">Safetree-Consulting</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="https://www.safetree.at/" target="_blank" rel="noopener">Safetree Consulting e.U.</a>, AT</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/reinhard-stidl/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Reinhard Stidl" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2021/09/Reinhard-Stidl.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Reinhard Stidl</div><div class="gt-profession">Senior Toxicologist - Managing Director</div><div class="gt-company">Safetree Consulting e.U.</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-635186"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-635186" aria-expanded="true" aria-controls="event-schedule-collapse-635186"><div class="gt-inner"><div class="gt-date">December 5, 2024</div><div class="gt-time">15:50</div><div class="gt-title">Validation of the Enhanced Ames Test for Nitrosamines</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-635186" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-635186"><div class="gt-panel-body"><div class="gt-text"><p><span style="color: #ff9900">◆ </span>Optimization of test conditions.</p> <p><span style="color: #ff9900">◆ </span>Selection of positive controls.</p> <p><span style="color: #ff9900">◆ </span>Collecting historical control data.</p> <p><span style="color: #ff9900">◆ </span>Follow-up for positive or negative responses.</p> <p><div class="vc_row wpb_row vc_row-fluid gt-background-position-initial gt-background-attachment-initial gt-overflow-hidden gt-text-default"><div class="wpb_column vc_column_container vc_col-sm-3"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <div class="su-custom-gallery su-custom-gallery-align-left su-custom-gallery-title-never"><div class="su-custom-gallery-slide" style="width:130px;height:60px"><a><img class="lazy" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20130%2060'%3E%3C/svg%3E" data-src="https://www.uventia.com/wp-content/uploads/2023/07/Charles-River-Laboratories-130x60.png?x85084" alt="Charles-River-Laboratories" width="130" height="60" /><span class="su-custom-gallery-title">Charles-River-Laboratories</span></a></div><div class="su-clear"></div></div> </div> </div> </div></div></div><div class="wpb_column vc_column_container vc_col-sm-9"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h6><a href="https://www.criver.com/" target="_blank" rel="noopener">Charles River Laboratories</a>, USA</h6> </div> </div> </div></div></div></div></p> </div><div class="gt-schedule-speakers"><div class="gt-title">Speakers:</div><div class="gt-list"><ul><li><a href="https://www.uventia.com/speaker/leon-f-stankowski/"><div class="gt-image"><img width="85" height="85" src="data:image/svg+xml,%3Csvg%20xmlns%3D%27https://www.w3.org/2000/svg%27%20viewBox%3D%270%200%203%202%27%3E%3C/svg%3E" class="attachment-eventchamp-avatar size-eventchamp-avatar gt-lazy-load" alt="Leon F. Stankowski" decoding="async" loading="lazy" data-src="https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-85x85.jpg?x85084" data-srcset="https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-85x85.jpg 85w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-300x300.jpg 300w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-150x150.jpg 150w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski-100x100.jpg 100w, https://www.uventia.com/wp-content/uploads/2023/07/Leon-F.-Stankowski.jpg 350w" data-sizes="auto, (max-width: 85px) 100vw, 85px" /></div><div class="gt-detail"><div class="gt-name">Leon F. Stankowski, Jr.</div><div class="gt-profession">Senior Scientific Director, Genetic and In Vitro Toxicology</div><div class="gt-company">Charles River Laboratories</div></div></a></li></ul></div></div></div></div></div><div class="gt-panel"><div class="gt-panel-heading" role="tab" id="event-schedule-heading-954565"><a role="button" data-toggle="collapse" data-parent="#event-schedule-accardion-441144" href="#event-schedule-collapse-954565" aria-expanded="true" aria-controls="event-schedule-collapse-954565"><div class="gt-inner"><div class="gt-date">December 5, 2024</div><div class="gt-time">16:20 - 16:30</div><div class="gt-title">🎤 Chairman’s closing remarks and end of DAY TWO</div></div><svg xmlns="https://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round"><polyline points="6 9 12 15 18 9"></polyline></svg></a></div><div id="event-schedule-collapse-954565" class="gt-panel-collapse collapse" role="tabpanel" aria-labelledby="event-schedule-heading-954565"><div class="gt-panel-body"></div></div></div></div></div></div></div></div></div><div class="vc_empty_space" style="height: 32px"><span class="vc_empty_space_inner"></span></div><div class="gt-button gt-style-2 gt-align-center gt-inline-false gt-margin-false"><a href="https://www.uventia.com/registration-4th-annual-genotoxic-impurities-summit-nitrosamines-beyond-2024/" target="_parent"><i class="fa-regular fa-pen-to-square"></i><span>REGISTER NOW</span></a></div></div></div></div></div></p> </div></div></div></div> </div> <div class="col-md-4 col-sm-12 col-xs-12 gt-site-right gt-fixed-sidebar"><div class="theiaStickySidebar"> <div class="gt-show-desktop"><div class="gt-widget gt-detail-widget"><div class="gt-widget-title"><span>Event Details</span></div><div class="gt-widget-content"><div class="gt-content-detail-box"><ul><li class="gt-event-counter"><div class="gt-content"><div class="gt-event-starting-time"><div class="gt-days"><div class="gt-count"></div><div class="gt-title">Days</div></div><div class="gt-hours"><div class="gt-count"></div><div class="gt-title">Hours</div></div><div class="gt-minutes"><div class="gt-count"></div><div class="gt-title">Min</div></div><div class="gt-secondes"><div class="gt-count"></div><div class="gt-title">Sec</div></div></div></div></li><li class="gt-start-date"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 59 59" xml:space="preserve"> <g> <path d="M51.179,40.429l-5.596,8.04l-3.949-3.241c-0.426-0.352-1.057-0.288-1.407,0.138c-0.351,0.427-0.289,1.058,0.139,1.407 l4.786,3.929c0.18,0.148,0.404,0.228,0.634,0.228c0.045,0,0.091-0.003,0.137-0.01c0.276-0.038,0.524-0.19,0.684-0.419l6.214-8.929 c0.315-0.453,0.204-1.076-0.25-1.392C52.116,39.861,51.494,39.975,51.179,40.429z"/> <path 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<g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Start Date</div><div class="gt-inner">December 4, 2024 11:50 am</div></div></li><li class="gt-end-date"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 59 59" xml:space="preserve"> <g> <path d="M50.95,41.13c-0.391-0.391-1.023-0.391-1.414,0L46,44.666l-3.536-3.536c-0.391-0.391-1.023-0.391-1.414,0 s-0.391,1.023,0,1.414l3.536,3.536l-3.536,3.536c-0.391,0.391-0.391,1.023,0,1.414c0.195,0.195,0.451,0.293,0.707,0.293 s0.512-0.098,0.707-0.293L46,47.494l3.536,3.536c0.195,0.195,0.451,0.293,0.707,0.293s0.512-0.098,0.707-0.293 c0.391-0.391,0.391-1.023,0-1.414l-3.536-3.536l3.536-3.536C51.34,42.153,51.34,41.521,50.95,41.13z"/> <path d="M52,34.479V15V5c0-0.553-0.448-1-1-1h-5V1c0-0.553-0.448-1-1-1h-7c-0.552,0-1,0.447-1,1v3H15V1c0-0.553-0.448-1-1-1H7 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c0.174-0.293,0.36-0.577,0.557-0.851c0.049-0.068,0.1-0.135,0.151-0.202c0.18-0.238,0.37-0.467,0.568-0.688 c0.069-0.077,0.138-0.155,0.209-0.23c0.196-0.208,0.402-0.405,0.613-0.596c0.075-0.068,0.148-0.138,0.225-0.204 c0.248-0.212,0.505-0.411,0.77-0.6c0.042-0.03,0.082-0.063,0.124-0.093c1.305-0.902,2.804-1.52,4.412-1.79l0.021-0.003 C44.778,35.064,45.381,35,46,35c0.389,0,0.776,0.021,1.16,0.063c0.06,0.006,0.118,0.02,0.178,0.027 c0.328,0.041,0.655,0.09,0.978,0.16c0.04,0.009,0.078,0.021,0.117,0.03c0.344,0.079,0.685,0.171,1.022,0.284 c0.023,0.008,0.045,0.017,0.068,0.025c0.345,0.118,0.685,0.253,1.022,0.406C54.347,37.729,57,41.557,57,46 C57,52.065,52.065,57,46,57z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">End Date</div><div class="gt-inner">December 5, 2024 5:00 pm</div></div></li><li class="gt-status"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 52 52" xml:space="preserve"> <g> <path d="M26,0C11.664,0,0,11.663,0,26s11.664,26,26,26s26-11.663,26-26S40.336,0,26,0z M26,50C12.767,50,2,39.233,2,26 S12.767,2,26,2s24,10.767,24,24S39.233,50,26,50z"/> <path d="M38.252,15.336l-15.369,17.29l-9.259-7.407c-0.43-0.345-1.061-0.274-1.405,0.156c-0.345,0.432-0.275,1.061,0.156,1.406 l10,8C22.559,34.928,22.78,35,23,35c0.276,0,0.551-0.114,0.748-0.336l16-18c0.367-0.412,0.33-1.045-0.083-1.411 C39.251,14.885,38.62,14.922,38.252,15.336z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Status</div><div class="gt-inner"><div class="gt-event-status">Upcoming</div></div></div></li><li class="gt-locations"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 54.757 54.757" xml:space="preserve"> <g> <path d="M27.557,12c-3.859,0-7,3.141-7,7s3.141,7,7,7s7-3.141,7-7S31.416,12,27.557,12z M27.557,24c-2.757,0-5-2.243-5-5 s2.243-5,5-5s5,2.243,5,5S30.314,24,27.557,24z"/> <path d="M40.94,5.617C37.318,1.995,32.502,0,27.38,0c-5.123,0-9.938,1.995-13.56,5.617c-6.703,6.702-7.536,19.312-1.804,26.952 L27.38,54.757L42.721,32.6C48.476,24.929,47.643,12.319,40.94,5.617z M41.099,31.431L27.38,51.243L13.639,31.4 C8.44,24.468,9.185,13.08,15.235,7.031C18.479,3.787,22.792,2,27.38,2s8.901,1.787,12.146,5.031 C45.576,13.08,46.321,24.468,41.099,31.431z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Location</div><div class="gt-inner"><ul><li><a href="https://www.uventia.com/location/online/?post_type=event">Online</a></li></ul></div></div></li><li class="gt-ticket-price"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 59.997 59.997" style="enable-background:new 0 0 59.997 59.997;" xml:space="preserve"> <g> <path d="M19.519,21.05c-0.39,0.4-0.38,1.03,0.01,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.3 c0.39-0.391,0.39-1.021,0-1.41C20.539,20.66,19.908,20.66,19.519,21.05z"/> <path d="M16.668,46.56c-0.39,0.391-0.39,1.03,0,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.29 c0.39-0.39,0.39-1.029,0-1.42C17.688,46.17,17.059,46.17,16.668,46.56z"/> <path d="M16.708,23.89c-0.39,0.391-0.39,1.03,0,1.42c0.2,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.39,0.38-1.03-0.01-1.41C17.729,23.5,17.088,23.5,16.708,23.89z"/> <path d="M19.499,49.39c-0.39,0.391-0.39,1.03,0,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.52-0.1,0.71-0.29 c0.39-0.39,0.39-1.029,0-1.42C20.519,49,19.888,49,19.499,49.39z"/> <path 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d="M47.448,29.35c-0.39,0.4-0.38,1.03,0.02,1.42c0.19,0.19,0.44,0.28,0.7,0.28c0.26,0,0.52-0.1,0.71-0.3 c0.39-0.4,0.38-1.03-0.02-1.42C48.468,28.95,47.828,28.96,47.448,29.35z"/> <circle cx="50.499" cy="19" r="1"/> <path d="M27.918,49.41c-0.39,0.399-0.38,1.029,0.02,1.42c0.19,0.189,0.44,0.279,0.69,0.279c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.399,0.38-1.029-0.02-1.41C28.928,49.01,28.298,49.02,27.918,49.41z"/> <circle cx="50.499" cy="27" r="1"/> <circle cx="50.499" cy="23" r="1"/> <path d="M33.499,43.68c-0.39,0.4-0.38,1.03,0.02,1.42c0.19,0.19,0.44,0.28,0.69,0.28c0.26,0,0.52-0.1,0.72-0.3 c0.39-0.4,0.38-1.03-0.02-1.42C34.508,43.28,33.878,43.29,33.499,43.68z"/> <path d="M39.918,9c0-0.55-0.45-1-1-1c-0.56,0-1,0.45-1,1s0.44,1,1,1C39.468,10,39.918,9.55,39.918,9z"/> <path d="M27.968,12.53c-0.39,0.39-0.38,1.029,0.01,1.42c0.19,0.189,0.45,0.29,0.7,0.29c0.26,0,0.52-0.101,0.71-0.301 c0.39-0.39,0.39-1.02,0-1.409C28.988,12.14,28.358,12.14,27.968,12.53z"/> <path d="M30.789,9.689c-0.39,0.4-0.39,1.03,0.01,1.42c0.19,0.19,0.45,0.29,0.7,0.29c0.26,0,0.51-0.1,0.71-0.3 c0.39-0.39,0.39-1.02-0.01-1.41C31.809,9.3,31.178,9.3,30.789,9.689z"/> <path d="M34.918,8c-0.56,0-1,0.45-1,1s0.44,1,1,1c0.55,0,1-0.45,1-1S35.468,8,34.918,8z"/> <path d="M36.289,40.819c-0.39,0.391-0.38,1.03,0.02,1.41c0.19,0.19,0.44,0.28,0.69,0.28c0.26,0,0.52-0.1,0.72-0.3 c0.38-0.391,0.38-1.03-0.02-1.41C37.309,40.41,36.668,40.42,36.289,40.819z"/> <path d="M59.206,0.293c-0.391-0.391-1.023-0.391-1.414,0L54.084,4H30.802L1.532,33.511c-0.667,0.666-1.034,1.553-1.034,2.495 s0.367,1.829,1.034,2.495l20.466,20.466c0.687,0.687,1.588,1.03,2.491,1.03c0.906,0,1.814-0.346,2.508-1.04l28.501-29.271V5.414 l3.707-3.707C59.596,1.316,59.596,0.684,59.206,0.293z M53.499,28.874L25.574,57.553c-0.595,0.596-1.565,0.596-2.162,0 L2.946,37.087c-0.289-0.289-0.448-0.673-0.448-1.081s0.159-0.792,0.451-1.084L31.635,6h20.45l-4.833,4.833 C46.461,10.309,45.516,10,44.499,10c-2.757,0-5,2.243-5,5s2.243,5,5,5s5-2.243,5-5c0-1.017-0.309-1.962-0.833-2.753l4.833-4.833 V28.874z M47.499,15c0,1.654-1.346,3-3,3s-3-1.346-3-3s1.346-3,3-3c0.462,0,0.894,0.114,1.285,0.301l-1.992,1.992 c-0.391,0.391-0.391,1.023,0,1.414C43.987,15.902,44.243,16,44.499,16s0.512-0.098,0.707-0.293l1.992-1.992 C47.385,14.106,47.499,14.538,47.499,15z"/> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Price</div><div class="gt-inner"><ul><div class="gt-price"><span></span>€415 - €595</div></ul></div></div></li><li class="gt-organizers"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 60 60" xml:space="preserve"> <path d="M48.014,42.889l-9.553-4.776C37.56,37.662,37,36.756,37,35.748v-3.381c0.229-0.28,0.47-0.599,0.719-0.951 c1.239-1.75,2.232-3.698,2.954-5.799C42.084,24.97,43,23.575,43,22v-4c0-0.963-0.36-1.896-1-2.625v-5.319 c0.056-0.55,0.276-3.824-2.092-6.525C37.854,1.188,34.521,0,30,0s-7.854,1.188-9.908,3.53C17.724,6.231,17.944,9.506,18,10.056 v5.319c-0.64,0.729-1,1.662-1,2.625v4c0,1.217,0.553,2.352,1.497,3.109c0.916,3.627,2.833,6.36,3.503,7.237v3.309 c0,0.968-0.528,1.856-1.377,2.32l-8.921,4.866C8.801,44.424,7,47.458,7,50.762V54c0,4.746,15.045,6,23,6s23-1.254,23-6v-3.043 C53,47.519,51.089,44.427,48.014,42.889z M51,54c0,1.357-7.412,4-21,4S9,55.357,9,54v-3.238c0-2.571,1.402-4.934,3.659-6.164 l8.921-4.866C23.073,38.917,24,37.354,24,35.655v-4.019l-0.233-0.278c-0.024-0.029-2.475-2.994-3.41-7.065l-0.091-0.396l-0.341-0.22 C19.346,23.303,19,22.676,19,22v-4c0-0.561,0.238-1.084,0.67-1.475L20,16.228V10l-0.009-0.131c-0.003-0.027-0.343-2.799,1.605-5.021 C23.253,2.958,26.081,2,30,2c3.905,0,6.727,0.951,8.386,2.828c1.947,2.201,1.625,5.017,1.623,5.041L40,16.228l0.33,0.298 C40.762,16.916,41,17.439,41,18v4c0,0.873-0.572,1.637-1.422,1.899l-0.498,0.153l-0.16,0.495c-0.669,2.081-1.622,4.003-2.834,5.713 c-0.297,0.421-0.586,0.794-0.837,1.079L35,31.623v4.125c0,1.77,0.983,3.361,2.566,4.153l9.553,4.776 C49.513,45.874,51,48.28,51,50.957V54z"/> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Organizer</div><div class="gt-inner"><ul><li><a href="https://www.uventia.com/event-organizer/uventia/?post_type=event">Uventia</a></li></ul></div></div></li><li class="gt-categories"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 60 60" xml:space="preserve"> <path d="M57.49,21.5H54v-6.268c0-1.507-1.226-2.732-2.732-2.732H26.515l-5-7H2.732C1.226,5.5,0,6.726,0,8.232v43.687l0.006,0 c-0.005,0.563,0.17,1.114,0.522,1.575C1.018,54.134,1.76,54.5,2.565,54.5h44.759c1.156,0,2.174-0.779,2.45-1.813L60,24.649v-0.177 C60,22.75,58.944,21.5,57.49,21.5z M2,8.232C2,7.828,2.329,7.5,2.732,7.5h17.753l5,7h25.782c0.404,0,0.732,0.328,0.732,0.732V21.5 H12.731c-0.144,0-0.287,0.012-0.426,0.036c-0.973,0.163-1.782,0.873-2.023,1.776L2,45.899V8.232z M47.869,52.083 c-0.066,0.245-0.291,0.417-0.545,0.417H2.565c-0.243,0-0.385-0.139-0.448-0.222c-0.063-0.082-0.16-0.256-0.123-0.408l10.191-27.953 c0.066-0.245,0.291-0.417,0.545-0.417H54h3.49c0.38,0,0.477,0.546,0.502,0.819L47.869,52.083z"/> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Category</div><div class="gt-inner"><ul><li><a href="https://www.uventia.com/event-category/pharma/?post_type=event">Pharma</a></li></ul></div></div></li><li class="gt-email"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 512 512" xml:space="preserve"> <g> <g> <g> <path d="M486.4,59.733H25.6c-14.138,0-25.6,11.461-25.6,25.6v341.333c0,14.138,11.461,25.6,25.6,25.6h460.8 c14.138,0,25.6-11.461,25.6-25.6V85.333C512,71.195,500.539,59.733,486.4,59.733z M494.933,426.667 c0,4.713-3.82,8.533-8.533,8.533H25.6c-4.713,0-8.533-3.82-8.533-8.533V85.333c0-4.713,3.82-8.533,8.533-8.533h460.8 c4.713,0,8.533,3.82,8.533,8.533V426.667z"/> <path d="M470.076,93.898c-2.255-0.197-4.496,0.51-6.229,1.966L266.982,261.239c-6.349,5.337-15.616,5.337-21.965,0L48.154,95.863 c-2.335-1.96-5.539-2.526-8.404-1.484c-2.865,1.042-4.957,3.534-5.487,6.537s0.582,6.06,2.917,8.02l196.864,165.367 c12.688,10.683,31.224,10.683,43.913,0L474.82,108.937c1.734-1.455,2.818-3.539,3.015-5.794c0.197-2.255-0.51-4.496-1.966-6.229 C474.415,95.179,472.331,94.095,470.076,93.898z"/> <path d="M164.124,273.13c-3.021-0.674-6.169,0.34-8.229,2.65l-119.467,128c-2.162,2.214-2.956,5.426-2.074,8.392 c0.882,2.967,3.301,5.223,6.321,5.897c3.021,0.674,6.169-0.34,8.229-2.65l119.467-128c2.162-2.214,2.956-5.426,2.074-8.392 C169.563,276.061,167.145,273.804,164.124,273.13z"/> <path d="M356.105,275.78c-2.059-2.31-5.208-3.324-8.229-2.65c-3.021,0.674-5.439,2.931-6.321,5.897 c-0.882,2.967-0.088,6.178,2.074,8.392l119.467,128c3.24,3.318,8.536,3.442,11.927,0.278c3.391-3.164,3.635-8.456,0.549-11.918 L356.105,275.78z"/> </g> </g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> <g> </g> </svg></div><div class="gt-content"><div class="gt-title">Email</div><div class="gt-inner"><a href="mailto:register@uventia.com">register@uventia.com</a></div></div></li><li class="gt-social-links"><div class="gt-icon"><svg version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 58.995 58.995" xml:space="preserve"> <path d="M39.927,41.929c-0.524,0.524-0.975,1.1-1.365,1.709l-17.28-10.489c0.457-1.144,0.716-2.388,0.716-3.693 c0-1.305-0.259-2.549-0.715-3.693l17.284-10.409C40.342,18.142,43.454,20,46.998,20c5.514,0,10-4.486,10-10s-4.486-10-10-10 s-10,4.486-10,10c0,1.256,0.243,2.454,0.667,3.562L20.358,23.985c-1.788-2.724-4.866-4.529-8.361-4.529c-5.514,0-10,4.486-10,10 s4.486,10,10,10c3.495,0,6.572-1.805,8.36-4.529L37.661,45.43c-0.43,1.126-0.664,2.329-0.664,3.57c0,2.671,1.04,5.183,2.929,7.071 c1.949,1.949,4.51,2.924,7.071,2.924s5.122-0.975,7.071-2.924c1.889-1.889,2.929-4.4,2.929-7.071s-1.04-5.183-2.929-7.071 C50.169,38.029,43.826,38.029,39.927,41.929z 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