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(PDF) Comparison of Oral and Intra Venous Midazolam for Sedation in Children Undergoing Upper Gastrointestinal Endoscopy | Sanaz Mehrabani - Academia.edu
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[{"id":90002890,"identifier":"Attachment_90002890","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":85245443,"created_at":"2022-08-20T19:19:24.815-07:00","from_world_paper_id":213198774,"updated_at":"2024-11-24T23:36:12.914-08:00","_data":{"publisher":"CASPIAN JOURNAL OF PEDIATRICS","grobid_abstract":"Background: Selecting the best medication for upper GI endoscopy in children is a challenging issue. The goal of this study was to compare the effects of oral and intravenous midazolam for upper gastrointestinal endoscopy (UGIE) on children. Methods: In this randomized clinical trial study conducted in Amirkola Children's Hospital, 110 children were randomly assigned to oral or intravenous groups. An expert nurse recorded O2 saturation, heart rate before, during and 5 minutes after endoscopy for all patients. Sedation, separation from parents and child cooperation were recorded. Results: Heart rate before and during endoscopy was not significantly different between two groups while heart rate was significantly lower in IV group after endoscopy. Cooperation during bite block was significantly better in oral group. Cooperation during endoscopy was not significantly different between two groups. Separation from parents in both male and female ones was significantly better in oral group. Complications were reported in 7 cases in oral group and 6 in IV group. Conclusion: Oral midazolam in comparison with IV midazolam is better and may be a method of choice for pediatric UGIE purposes.","publication_date":"2015,9,15","publication_name":"CASPIAN JOURNAL OF PEDIATRICS","grobid_abstract_attachment_id":"90002890"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Comparison of Oral and Intra Venous Midazolam for Sedation in Children Undergoing Upper Gastrointestinal Endoscopy","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [203530001]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div 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translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Comparison of Oral and Intra Venous Midazolam for Sedation in Children Undergoing Upper Gastrointestinal Endoscopy</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="203530001" href="https://independent.academia.edu/SanazMehrabani"><img alt="Profile image of Sanaz Mehrabani" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Sanaz Mehrabani</a></div><div class="ds-work-card--detail"><p class="ds-work-card--detail ds2-5-body-sm">2015, CASPIAN JOURNAL OF PEDIATRICS</p></div><div class="ds-work-card--button-container"><button class="ds2-5-button 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data-landing_url="https://www.academia.edu/85245443/Comparison_of_Oral_and_Intra_Venous_Midazolam_for_Sedation_in_Children_Undergoing_Upper_Gastrointestinal_Endoscopy" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="85245437" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/85245437/Mohammadreza_Esmaeilidooki_MD_1_Sanaz_Mehrabani_MD_1_Ozra_Molai_MD_2_Manuchehr_Askari_MD_1_Comparison_of_oral_and_intra_venous_midazolam_for_sedation_in_children_undergoing_upper_gastrointestinal_endoscopy">Mohammadreza Esmaeilidooki (MD) 1 Sanaz Mehrabani (MD) 1 * Ozra Molai (MD) 2 Manuchehr Askari (MD) 1 Comparison of oral and intra venous midazolam for sedation in children undergoing upper gastrointestinal endoscopy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="203530001" href="https://independent.academia.edu/SanazMehrabani">Sanaz Mehrabani</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Citation: Esmaeilidooki MR, Mehrabani S, Molai O, et al. Comparison of oral and intra venous midazolam for sedation in children undergoing upper gastrointestinal endoscopy. Caspian J of Pediatr Sep 2015; 1(2): 60-64. Abstract: Background: Selecting the best medication for upper GI endoscopy in children is a challenging issue. The goal of this study was to compare the effects of oral and intravenous midazolam for upper gastrointestinal endoscopy (UGIE) on children. Methods: In this randomized clinical trial study conducted in Amirkola Children&#39;s Hospital, 110 children were randomly assigned to oral or intravenous groups. An expert nurse recorded O2 saturation, heart rate before, during and 5 minutes after endoscopy for all patients. Sedation, separation from parents and child cooperation were recorded. Results: Heart rate before and during endoscopy was not significantly different between two groups while heart rate was significantly lower in IV group after endoscopy. Cooperation...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Mohammadreza Esmaeilidooki (MD) 1 Sanaz Mehrabani (MD) 1 * Ozra Molai (MD) 2 Manuchehr Askari (MD) 1 Comparison of oral and intra venous midazolam for sedation in children undergoing upper gastrointestinal endoscopy","attachmentId":90002879,"attachmentType":"pdf","work_url":"https://www.academia.edu/85245437/Mohammadreza_Esmaeilidooki_MD_1_Sanaz_Mehrabani_MD_1_Ozra_Molai_MD_2_Manuchehr_Askari_MD_1_Comparison_of_oral_and_intra_venous_midazolam_for_sedation_in_children_undergoing_upper_gastrointestinal_endoscopy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/85245437/Mohammadreza_Esmaeilidooki_MD_1_Sanaz_Mehrabani_MD_1_Ozra_Molai_MD_2_Manuchehr_Askari_MD_1_Comparison_of_oral_and_intra_venous_midazolam_for_sedation_in_children_undergoing_upper_gastrointestinal_endoscopy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="13760541" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/13760541/Use_of_oral_midazolam_in_pediatric_upper_gastrointestinal_endoscopy">Use of oral midazolam in pediatric upper gastrointestinal endoscopy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32949449" href="https://tbzmed.academia.edu/GhojazadehM">Ghojazadeh M</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32876545" href="https://tbzmed.academia.edu/MandanaRafeey">Mandana Rafeey</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Pediatrics International, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Use of oral midazolam in pediatric upper gastrointestinal endoscopy","attachmentId":44984221,"attachmentType":"pdf","work_url":"https://www.academia.edu/13760541/Use_of_oral_midazolam_in_pediatric_upper_gastrointestinal_endoscopy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/13760541/Use_of_oral_midazolam_in_pediatric_upper_gastrointestinal_endoscopy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="100803835" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/100803835/Oral_Ketamine_or_Nasal_Midazolam_for_Sedation_in_Pediatric_Upper_Gastrointestinal_Endoscopy">Oral Ketamine or Nasal Midazolam for Sedation in Pediatric Upper Gastrointestinal Endoscopy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="78765550" href="https://gums.academia.edu/CaspianJournalofNeurologicalSciencesCJNS">Caspian Journal of Neurological Sciences (CJNS)</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Caspian Journal of Neurological Sciences, 2023</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: There is no agreement on the route of administration and the drug of choice for providing adequate sedation for pediatric invasive procedures. Objectives: We compared the utility, safety, and sedation effects of intranasal midazolam and oral ketamine. Materials & Methods: This double-blind clinical trial was performed on 100 children aged 2 to 14 years who were candidates for upper gastrointestinal (GI) endoscopy. Patients were randomly assigned to two groups: ketamine (4 mg/kg orally) and midazolam (0.1 mg/ kg intranasal). Sedation score, fear levels, children’s behavior at the time of separation from parents, and vital signs were recorded. Results: Higher systolic blood pressure was seen in children who received ketamine (P=0.012) and lower arterial oxygen saturation in the midazolam group (P=0.023). Also, the level of sedation showed no significant difference between the groups. Conclusion: Based on the results, administering oral ketamine or intranasal midazolam before endoscopy induced a similar sedation score in children. Also, both methods could be safe and non-invasive modalities for sedation.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Oral Ketamine or Nasal Midazolam for Sedation in Pediatric Upper Gastrointestinal Endoscopy","attachmentId":101521351,"attachmentType":"pdf","work_url":"https://www.academia.edu/100803835/Oral_Ketamine_or_Nasal_Midazolam_for_Sedation_in_Pediatric_Upper_Gastrointestinal_Endoscopy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/100803835/Oral_Ketamine_or_Nasal_Midazolam_for_Sedation_in_Pediatric_Upper_Gastrointestinal_Endoscopy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="116135647" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/116135647/A_comparison_of_sedation_with_midazolam_ketamine_versus_propofol_fentanyl_during_endoscopy_in_children_a_randomized_trial">A comparison of sedation with midazolam–ketamine versus propofol–fentanyl during endoscopy in children: a randomized trial</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="174635272" href="https://independent.academia.edu/DrBilal%C5%9Eeng%C3%BC">Dr Bilal Şengü</a></div><p class="ds-related-work--metadata ds2-5-body-xs">European Journal of Gastroenterology &amp; Hepatology, 2017</p><p class="ds-related-work--abstract ds2-5-body-sm">Purpose We aimed to compare the efficacy and safety of midazolam plus ketamine versus fentanyl plus propofol combination administered to children undergoing upper gastrointestinal endoscopy (UGE) and to determine the most appropriate sedation protocol. Materials and methods This prospective, randomized, single-blind study included patients between the ages of 4 and 17 years who underwent UGE for diagnostic purposes. Patients were divided randomly into groups A (midazolam–ketamine combination, n=119) and B (fentanyl plus propofol combination, n=119). The effectiveness of the sedation and complications during the procedure and recovery period were recorded. Results The processes started without an additional dose of the drug for 118 patients (99.1%) in group A and for 101 patients (84.8%) in group B (P=0.001). The average dose of ketamine administered to the patients in group A was 1.03±0.15 mg/kg and the average dose of propofol administered to the patients in group B was 1.46±0.55 m...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A comparison of sedation with midazolam–ketamine versus propofol–fentanyl during endoscopy in children: a randomized trial","attachmentId":112349387,"attachmentType":"pdf","work_url":"https://www.academia.edu/116135647/A_comparison_of_sedation_with_midazolam_ketamine_versus_propofol_fentanyl_during_endoscopy_in_children_a_randomized_trial","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/116135647/A_comparison_of_sedation_with_midazolam_ketamine_versus_propofol_fentanyl_during_endoscopy_in_children_a_randomized_trial"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="65480421" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/65480421/A_comparison_of_sedation_with_midazolam_ketamine_versus_propofol_fentanyl_during_endoscopy_in_children">A comparison of sedation with midazolam–ketamine versus propofol–fentanyl during endoscopy in children</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33396155" href="https://ktu.academia.edu/EnginErturk">Engin Erturk</a></div><p class="ds-related-work--metadata ds2-5-body-xs">European Journal of Gastroenterology & Hepatology, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A comparison of sedation with midazolam–ketamine versus propofol–fentanyl during endoscopy in children","attachmentId":77058107,"attachmentType":"pdf","work_url":"https://www.academia.edu/65480421/A_comparison_of_sedation_with_midazolam_ketamine_versus_propofol_fentanyl_during_endoscopy_in_children","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/65480421/A_comparison_of_sedation_with_midazolam_ketamine_versus_propofol_fentanyl_during_endoscopy_in_children"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="103727745" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/103727745/Efficacy_and_safety_of_midazolam_and_ketamine_in_paediatric_upper_endoscopy">Efficacy and safety of midazolam and ketamine in paediatric upper endoscopy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="100267984" href="https://independent.academia.edu/AhmetBasturk">Ahmet Basturk</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Arab Journal of Gastroenterology, 2017</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Efficacy and safety of midazolam and ketamine in paediatric upper endoscopy","attachmentId":103656302,"attachmentType":"pdf","work_url":"https://www.academia.edu/103727745/Efficacy_and_safety_of_midazolam_and_ketamine_in_paediatric_upper_endoscopy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/103727745/Efficacy_and_safety_of_midazolam_and_ketamine_in_paediatric_upper_endoscopy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="47920757" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/47920757/Sedation_for_pediatric_GI_endoscopy">Sedation for pediatric GI endoscopy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="41340918" href="https://independent.academia.edu/MarkGilger">Mark Gilger</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Gastrointestinal Endoscopy, 2007</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Sedation for pediatric GI endoscopy","attachmentId":66800488,"attachmentType":"pdf","work_url":"https://www.academia.edu/47920757/Sedation_for_pediatric_GI_endoscopy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/47920757/Sedation_for_pediatric_GI_endoscopy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="59029702" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/59029702/Ketamine_and_midazolam_sedation_for_pediatric_gastrointestinal_endoscopy_in_the_Arab_world">Ketamine and midazolam sedation for pediatric gastrointestinal endoscopy in the Arab world</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="72066371" href="https://independent.academia.edu/WailHayajneh">Wail Hayajneh</a></div><p class="ds-related-work--metadata ds2-5-body-xs">World journal of gastroenterology : WJG, 2011</p><p class="ds-related-work--abstract ds2-5-body-sm">To evaluate the safety and effectiveness of intravenous ketamine-midazolam sedation during pediatric endoscopy in the Arab world. A retrospective cohort study of all pediatric endoscopic procedures performed between 2002-2008 at the shared endoscopy suite of King Abdullah University Hospital, Jordan University of Science & Technology, Jordan was conducted. All children were &gt; 1 year old and weighed &gt; 10 kg with American Society of Anesthesiologists class 1 or 2. Analysis was performed in terms of sedation-related complications (desaturation, respiratory distress, apnea, bradycardia, cardiac arrest, emergence reactions), adequacy of sedation, need for sedation reversal, or failure to complete the procedure. A total of 301 patients (including 160 males) with a mean age of 9.26 years (range, 1-18 years) were included. All were premedicated with atropine; and 79.4% (239/301) had effective and uneventful sedation. And 248 (82.4%) of the 301 patients received a mean dose of 0.16 mg/...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Ketamine and midazolam sedation for pediatric gastrointestinal endoscopy in the Arab world","attachmentId":73156042,"attachmentType":"pdf","work_url":"https://www.academia.edu/59029702/Ketamine_and_midazolam_sedation_for_pediatric_gastrointestinal_endoscopy_in_the_Arab_world","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/59029702/Ketamine_and_midazolam_sedation_for_pediatric_gastrointestinal_endoscopy_in_the_Arab_world"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="88131337" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/88131337/The_Effects_of_Sedation_with_Intravenous_Midazolam_in_1_Oo_Patients_Undergoing_Upper_Gastrointestinal_Endoscopy">The Effects of Sedation with Intravenous Midazolam in 1 Oo Patients Undergoing Upper Gastrointestinal Endoscopy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="114311925" href="https://bahcesehir.academia.edu/DemetKoc">Demet Koc</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Marmara Medical Journal, 2001</p><p class="ds-related-work--abstract ds2-5-body-sm">Objective: The use of sedation in upper gastrointestinal endoscopy is widespread because of better patient tolerance. As this sedation is usually performed by nonanesthesiologists in and outside of hospital settings, possible adverse effects arising during the procedure must be dealt with carefully. In this study, the safety and efficacy of midazolam for conscious sedation in 100 patients undergoing upper gastrointestinal endoscopy were evaluated prospectively. Patients and Methods: Hundred consecutive patients undergoing upper gastrointestinal endoscopy were sedated with intravenous midazolam. The dose of midazolam was titrated according to the patient’s need and the duration of the procedure. Heart rate and oxygen saturation of all the patients were continuously monitored during the procedure and any complications were recorded. The amnesic effect of midazolam and patient comfort were also evaluated. Results: During the procedure, absence of oxygen desaturation (Sa02 &gt; 95%) was...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"The Effects of Sedation with Intravenous Midazolam in 1 Oo Patients Undergoing Upper Gastrointestinal Endoscopy","attachmentId":92166694,"attachmentType":"pdf","work_url":"https://www.academia.edu/88131337/The_Effects_of_Sedation_with_Intravenous_Midazolam_in_1_Oo_Patients_Undergoing_Upper_Gastrointestinal_Endoscopy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/88131337/The_Effects_of_Sedation_with_Intravenous_Midazolam_in_1_Oo_Patients_Undergoing_Upper_Gastrointestinal_Endoscopy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="50523848" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/50523848/Propofol_with_and_without_Midazolam_for_Diagnostic_Upper_Gastrointestinal_Endoscopies_in_Children">Propofol with and without Midazolam for Diagnostic Upper Gastrointestinal Endoscopies in Children</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="42775072" href="https://independent.academia.edu/SeyfiKartal">Seyfi Kartal</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Pediatric Gastroenterology, Hepatology & Nutrition</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Propofol with and without Midazolam for Diagnostic Upper Gastrointestinal Endoscopies in Children","attachmentId":68474512,"attachmentType":"pdf","work_url":"https://www.academia.edu/50523848/Propofol_with_and_without_Midazolam_for_Diagnostic_Upper_Gastrointestinal_Endoscopies_in_Children","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/50523848/Propofol_with_and_without_Midazolam_for_Diagnostic_Upper_Gastrointestinal_Endoscopies_in_Children"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":90002890,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":90002890,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_90002890" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="98133777" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/98133777/A_Comparison_of_Oral_Diazepam_Versus_Midazolam_Administered_With_Intravenous_Meperidine_as_Premedication_to_Sedation_for_Pediatric_Endoscopy">A Comparison of Oral Diazepam Versus Midazolam, Administered With Intravenous Meperidine, as Premedication to Sedation for Pediatric Endoscopy</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="260623876" 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ds2-5-body-sm ds2-5-body-link" data-author-id="45009977" href="https://independent.academia.edu/YvanVandenplas">Yvan Vandenplas</a></div><p class="ds-related-work--metadata ds2-5-body-xs">World journal of gastrointestinal endoscopy, 2015</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Review on sedation for gastrointestinal tract endoscopy in children by non-anesthesiologists","attachmentId":43683463,"attachmentType":"pdf","work_url":"https://www.academia.edu/23194386/Review_on_sedation_for_gastrointestinal_tract_endoscopy_in_children_by_non_anesthesiologists","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/23194386/Review_on_sedation_for_gastrointestinal_tract_endoscopy_in_children_by_non_anesthesiologists"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="3" data-entity-id="118105875" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/118105875/Midazolam_Induced_Sedation_for_Upper_Gastrointestinal_Endoscopy">Midazolam-Induced Sedation for Upper Gastrointestinal Endoscopy</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="236035895" href="https://independent.academia.edu/OzdenNuri">Nuri Ozden</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Gastroenterology Nursing, 2003</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Midazolam-Induced Sedation for Upper Gastrointestinal Endoscopy","attachmentId":113808734,"attachmentType":"pdf","work_url":"https://www.academia.edu/118105875/Midazolam_Induced_Sedation_for_Upper_Gastrointestinal_Endoscopy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/118105875/Midazolam_Induced_Sedation_for_Upper_Gastrointestinal_Endoscopy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="4" data-entity-id="30544075" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/30544075/Efficacy_safety_and_cost_of_intravenous_sedation_versus_general_anesthesia_in_children_undergoing_endoscopic_procedures">Efficacy, safety, and cost of intravenous sedation versus general anesthesia in children undergoing endoscopic procedures</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58241403" href="https://independent.academia.edu/BarbieDrews">Barbie Drews</a><span>, </span><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58220363" href="https://structbio-pitt.academia.edu/RobertSquires">Robert Squires</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Gastrointestinal Endoscopy, 1995</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Efficacy, safety, and cost of intravenous sedation versus general anesthesia in children undergoing endoscopic procedures","attachmentId":50988130,"attachmentType":"pdf","work_url":"https://www.academia.edu/30544075/Efficacy_safety_and_cost_of_intravenous_sedation_versus_general_anesthesia_in_children_undergoing_endoscopic_procedures","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/30544075/Efficacy_safety_and_cost_of_intravenous_sedation_versus_general_anesthesia_in_children_undergoing_endoscopic_procedures"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="5" data-entity-id="1178127" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/1178127/Experience_of_intravenous_sedation_for_pediatric_gastrointestinal_endoscopy_in_a_large_tertiary_referral_center_in_a_developing_country">Experience of intravenous sedation for pediatric gastrointestinal endoscopy in a large tertiary referral center in a developing country</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="1070943" href="https://mahidol.academia.edu/SomchaiAmornyotin">Somchai Amornyotin</a></div><p class="ds-related-work--metadata 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