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---------------------------------------------------------------- ======================= CONTENT BLOCK ========================= ---------------------------------------------------------------- ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~*/ .h6-lh-contentbody { line-height: 27px; /* 168.75% */ } .rounded-corner-trb .tatsu-single-image-inner img { border-radius: 42px 42px 42px 0px; } .rounded-corner-tbl .tatsu-single-image-inner img { border-radius: 42px 0px 42px 42px; } .add-top-line.tatsu-H1VbOCFg7a { padding-top: 2px; border-top: 1px solid #000; } /* ======================== HOME * ========================= */ /*.img-zoom img { transition: all 1s ease-in-out; } .img-zoom img:hover { transform: scale(1.05); } */ .rotate img { animation: rotation 250s infinite linear; } @keyframes rotation { from { transform: rotate(0deg); } to { transform: rotate(359deg); } } /* --- TIMELINE CODE --- */ .timeline { /* Used to position the left vertical line */ position: relative; } 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button.active { background-color: #fff;/* #ccc; */ border-left: 2px solid #000; } /* Style the tab content */ .tabcontent { float: left; padding: 0px 12px; /* border: 1px solid #ccc; */ width: 50%; border-left: none; height: 100%;/*630px; 300px; */ } /* ---- END VERTICAL TAB ---- */ /* --- POST SLIDER - SEC 16 --- */ .post-archive-thumbnail .exp-posts-loop-style2 .be-slider .exp-post-thumb { width: 20%; border-radius: 50%; height: 8%; margin: 2em; } .slider-style .exp-post-inner { border-radius: 32px 0; } /* ======================== HCAb PLUS ========================= */ /* ======================== ADC ========================= */ .adc-btn-rounded-corner .tatsu-button.rounded{ border-radius: 10px; } .img-border img.tatsu-gradient-border { border: 1px solid rgba(125, 143, 164, .4); /*#7d8fa4; */ } /* ======================= INSIGHTS / POSTS / BLOG ========================= */ /* Add header image for single posts - publications */ .post-template-default.single.single-post .category-publications .exp-post-single-header-wide::after { background: rgba(1, 36, 78, 0.8); } .post-template-default.single.single-post .category-publications .exp-post-single-header-bg-wrap { background-color: #01244e; background: url(/wp-content/uploads/2023/12/Layer_1.png) no-repeat center center fixed; } /* change background image for case-studies */ .post-template-default.single.single-post .category-case-studies .exp-post-single-header-wide::after { background: rgba(221, 241, 255, 0.4); border-radius: 3px; background: linear-gradient(90deg, rgba(46, 167, 224, 0.85) 0%, rgba(31, 131, 144, 0.75) 100%); } .post-template-default.single.single-post .category-case-studies .exp-post-single-header-bg-wrap { background-color: #EA5515; background: url(/wp-content/uploads/2023/12/Group-7775.svg) no-repeat center center fixed; } /* -- Add header image for single posts - corporate-news -- */ .post-template-default.single.single-post .category-corporate-news .exp-post-single-header-wide::after { background: rgba(31, 131, 144, 0.8); } .post-template-default.single.single-post .category-corporate-news .exp-post-single-header-bg-wrap { background-color: #01244e; background: url(/wp-content/uploads/2024/01/beacon-explore-left-image.svg) no-repeat center center fixed; } /* Remove social icons */ .exp-post-single-footer-share, .exp-comments-without-content { display: none; } /* --- END POST SLIDER - SEC 16 --- */ /* ========================= INSIGHTS ========================= */ .insights-corporate .exp-post-inner { border-radius: 5px; } .insights-corporate .exp-posts-loop-style3 .exp-post-details { padding: 30px 40px; } .insights-corporate .exp-post-date { text-transform: uppercase; font-size: 20px; font-weight: 500; line-height: 125%; /* 125% 35px */ } .insights-corporate .exp-post-title { font-size: 28px; font-weight: 300; } .insights-corporate .exp-post-title:hover { color: #F18E25; } .insights-blog .exp-post-date, .insights-case-studies .exp-post-date { color: #F18E25;/* #fff; */ font-size: 18px; text-transform: uppercase; } .insights-blog .exp-post-title, .insights-case-studies .exp-post-title { font-size: 20px; color: #fff; } .exp-posts-loop-style2 .exp-img-object-fit { border-radius: 5px; border: 1px solid #DDF1FF; } .insights-corporate .exp-post-title a::after, .insights-blog .exp-post-title a::after { content: " Read more ▸ "; display: block; /*-vertical-align: bottom;-*/ font-size: 18px; font-weight: 600; margin-top: 1em; color: #F18E25; } /*.exp-read-more-underlined::before { color: rgba(241, 142, 37,1) !important; } , .insights-case-studies .exp-post-title a::after*/ a.exp-read-more.exp-read-more-underlined { color: rgba(241, 142, 37,1) !important; text-transform: initial; } .insights-case-studies .exp-post-title { font-size: 22px; color: #fff; } .exp-posts-loop .exp-post-content { color: #fff; font-size: 18px; } /* ======================= COMPANY ========================= */ /*.bio-pop-up .tatsu-accordion-expand::after, .bio-pop-up .tatsu-accordion-expand::before { display: none; } */ .bio-pop-up .tatsu-accordion .tatsu-accordion-expand { margin: unset !important; } .tatsu-accordion-style2.bio-pop-up .accordion-content.ui-accordion-content { padding: 40px;/*114px; */ background: #DDF1FF; border-radius: 40px; } .tatsu-accordion-style2 .accordion-head.ui-accordion-header { position: relative; } .bio-pop-up .tatsu-accordion-inner { background: linear-gradient(65deg, #F18E25, #EF8422, #EC6B1B, #EA5515); border-radius: 40px; } .tatsu-accordion-style2.bio-pop-up .accordion-head.ui-accordion-header { color: #fff; padding-left: 6.5em; } .tatsu-accordion.bio-pop-up .tatsu-accordion-expand { display: none; } /* --- BEGIN POP UP FOR READ BIO --- */ .pum-theme-read-bio .pum-close.popmake-close:hover { color: #fff; border: 1px solid #DDF1FF; background: linear-gradient(65deg, #F18E25, #EF8422, #EC6B1B, #EA5515); } .img-rounded-corner img.tatsu-gradient-border { border-radius: 10px; } /* ----- */ .bio-container { /* align-items: center; background: #F1EEF1; border: 1px solid #D2D1D4; */ display: flex; height: 100vh;/* 800px; */ width: 900px; margin-left: 5em; /* height: 360px; width: 360px; justify-content: center; */ } .readbio { background: linear-gradient(90deg, #EA5515 0.11%, #EC6B1B 26.06%, #EF8422 68.99%, #F18E25 99.93%); /* background: #DEDBDF; */ border-radius: 36px; padding: 1px 20px 50px;/* 10px 20px 24px; */ height: 32px; overflow: hidden; position: relative; width: 9.5em;/* 162px; */ -webkit-tap-highlight-color: transparent; transition: width 300ms cubic-bezier(0.4, 0.0, 0.2, 1), height 300ms cubic-bezier(0.4, 0.0, 0.2, 1), box-shadow 300ms cubic-bezier(0.4, 0.0, 0.2, 1), border-radius 300ms cubic-bezier(0.4, 0.0, 0.2, 1); } .remove-padding { padding: 0 !important; } .readbio:not(.expand) { cursor: pointer; } .readbio:not(.expand):hover { background: linear-gradient(90deg, #F18E25 0.11%, #EF8422 26.06%, #EC6B1B 68.99%, #EA5515 99.93%);/*#C2C0C2; */ } 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100%; */ } .name-large { color: #01244e; font-size: 45px;/* 45px; */ line-height: 70px; margin-left: 2em;/* 35px; */ margin-top: 2.5em; } .x-touch { align-items: top; /* center; */ align-self: top;/* center; */ margin-top: 3em; margin-right: 3.5em; cursor: pointer; display: flex; height: 55px;/* 50px; */ justify-content: center; margin-left: auto; width: 55px;/* 50px; */ } .x { background: #DDF1FF;/* #BA87F9; */ border-radius: 50%; height: 34px; /* height: 20px; */ position: relative; width: 37px;/* 22px;20px; */ border: 2px solid #000; padding: 6px; } .x-touch:hover .x { /* background: #CB9AFB; */ background: linear-gradient(90deg, #EA5515 0.11%, #EC6B1B 26.06%, #EF8422 68.99%, #F18E25 99.93%); } .line1 { background: #6422EB; height: 18px; /* height: 12px; */ width: 2px; position: absolute; transform: translateX(10px) translateY(0px) rotate(45deg); /* transform: translateX(9px) translateY(4px) rotate(45deg); */ } .line2 { background: #6422EB; height: 18px; /* height: 12px; */ position: absolute; transform: translateX(10px) translateY(0px) rotate(-45deg); width: 2px; } .bottom { background: #DDF1FF;/* #FFF; */ color: #EB5816;/* #444247; */ /* font-size: 16px; */ /* height: 100%; /* 600px; */ /* width: auto;/* 750px; */ /* height: 200px; width: 300px; */ /* padding-top: .6em;/* 5px; */ } .row { /* align-items: center; */ display: flex; flex-direction: row; height: 100vh; /* height: 60px; */ } .bio-detail { margin-left: 5.5em; color: #000; font-size: 1em; line-height: 144.44%; padding-right: 5em;/* 2em; */ padding-top: 1em; } /* .twitter { margin-left: 16px; height: 30px; position: relative; top: 0px; width: 30px; } */ /* .medium { height: 90px; /* 30px; *//* width: 90px;/* 30px; *//* margin-left: 16px; position: relative; } */ .title { text-transform: uppercase; font-size: 20px; margin-left: 4.4em; margin-top: 1em; } .link { margin-left: 16px; } .link a { color: #EB5816; text-decoration: none; } .link a:hover { color: #F18E25; } .readbio.expand { border-radius: 6px; box-shadow: 0 10px 20px rgba(0,0,0,0.10), 0 6px 6px rgba(0,0,0,0.16); height: 100%; width: 100%; /* height: 200px; width: 300px; */ } .expand .from { opacity: 0; transition: opacity 100ms cubic-bezier(0.4, 0.0, 1, 1); } .expand .from-contents { transform: scale(1.91); } .expand .to { opacity: 1; transition: opacity 200ms 100ms cubic-bezier(0.0, 0.0, 0.2, 1); } .expand .to-contents { transform: scale(1); } /* ----- */ /* --- END POP UP FOR READ BIO --- */ /* ========================= BEACON ========================= */ .link-white-no-margin .circular.mediumbtn { padding-left: 0px; } #image-overflow-visible.tatsu-section.tatsu-bg-overlay { overflow: visible; } /* Fade image doesn't work @keyframes fadeIn { from { opacity: 0.6; } } .img-fade { animation: fadeIn 2.5s infinite alternate; } */ /* ========================= IDEA TO IND ========================= */ .i-to-i-toggle .accordion-head.ui-accordion-header { text-align: center; display: block; } /* Add arrow for active accordion */ .i-to-i-toggle .ui-accordion-header-active::after { background: unset !important; content: " ▼"; padding-left: 5px; color: #EE771F; } /* make button circular */ .video-btn a { background: linear-gradient(to right, #F18E25, #EA5515); transition: all ease-in-out .5s; } .video-btn .circular.mediumbtn { padding: 12px 9px; } .video-btn .tatsu-button i { margin-right: 0.1em; vertical-align: top; margin-left: 0.2em; } .video-btn a:hover { background: linear-gradient(to right, #fff, #fff); color: #000 !important; } .orange-border.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad { background: linear-gradient(65deg, #F18E25, #EF8422, #EC6B1B, #EA5515); padding: 10% 10% !important; border-radius: 20px; z-index: 1; } .orange-border.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad::before { border-radius: 20px; background-color: #01244E; z-index: -1; transition: 700ms; } /* .orange-border-hover.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad { padding: 20% 10% !important; border: none; outline: none; position: relative; border-radius: 10px; background: linear-gradient(165deg, #001540, #001540, #001540, #001540); z-index: 1; cursor: pointer; transition: 700ms ease-in-out; } .orange-border.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad::before { content: ""; position: absolute; top: 2px; right: 2px; bottom: 2px; left: 2px; border-radius: 10px; background-color: #001540; z-index: -1; transition: 700ms; } * */ .min-space-icon .tatsu-button.right-icon i.tatsu-icon { margin: 0 0 0 .5em; } .min-space-icon.less-space-btn .circular.mediumbtn { margin-right: -30px; padding-bottom: 2px; } .pum-theme-809 #popmake-852.pum-container { height: auto; top: 251px !important; } .pum-theme-809 #popmake-864.pum-container { height: auto; top: 294px !important; } .pum-theme-809 #popmake-863.pum-container { height: auto;; top: 294px !important; } .pum-theme-809 #popmake-879.pum-container { height: auto; top: 442px !important; } .pum-theme-809 #popmake-880.pum-container { height: auto; top: 442px !important; } .pum-theme-809 #popmake-885.pum-container { height: auto; top: 442px !important; } .pum-theme-809 #popmake-888.pum-container { height: auto; top: 442px !important; } html.pum-open.pum-open-overlay.pum-open-scrollable body > :not([aria-modal="true"]) { padding-right: 0px; } .tatsu-column-inner.tatsu-column-sticky.is_stuck { margin-top: 5.7em; } /* body #be-content .pum-active { overflow-y: hidden !important; } html.pum-open.pum-open-overlay.pum-open-scrollable .pum-overlay.pum-active { position: fixed; width: 100%; height: 100%; overflow-y: hidden !important; -webkit-overflow-scrolling: auto; } */ /*~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ---------------------------------------------------------------- =================== FOOTER / FOOTER WIDGETS ==================== ---------------------------------------------------------------- ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~*/ /*~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ---------------------------------------------------------------- =================== PLUGIN / PLUGIN WIDGETS ==================== ---------------------------------------------------------------- ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~*/ /*~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ ---------------------------------------------------------------- ======================== MEDIA QUERIES ========================= ---------------------------------------------------------------- ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~*/ /*------------IPAD PORTRAIT-----------*/ @media only screen and (min-width: 768px) and (max-width: 1024px) { .non-gradient-btn.align-center { text-align: center; display: block !important; width: 100%; } .tatsu-SJbi7CWYO6.tatsu-text-block-wrap { margin-top: 0 !important; } .tatsu-SJbi7CWYO6.tatsu-text-block-wrap { margin-top: 0 !important; } .tatsu-r1jw-gXloT.tatsu-text-block-wrap { margin-top: 0 !important; } .tatsu-HyYwZlQxsT > .tatsu-row { margin-top: 0 !important; } } /*------WEIRD ONE------*/ @media only screen and (min-width: 320px) and (max-width: 900px) { } @media only screen and (min-width: 320px) and (max-width: 676px) { .link-white-no-margin.align-center { text-align: center; margin: 0 auto !important; display: block; width: 100% !important; padding-right: 0 !important; } .link-white-no-margin.align-center .circular.mediumbtn { padding: 0 0 20px !important; } .tatsu-rJh0bpplqT.tatsu-text-block-wrap { margin: 0 !important; } .nona-btn.center-align .tatsu-button { text-align: center !important; margin: 0 auto 1em !important; display: block !important; } #corporate-news .insights-corporate .exp-post-title-meta a { font-size: 24px !important; line-height: 1.4em !important; } #corporate-news .insights-corporate a.exp-post-date { font-size: 14px !important; line-height: 1em !important; } #publications .exp-post-details-inner a { font-size: 70% !important; line-height: 1.4em; } .tatsu-button-container, .tatsu-normal-button.tatsu-button-wrap { margin: 0 !important; } .tatsu-sub-menu > li.current-menu-item > a { color: #fff !important; } .center-align { text-align: center !important; } .clearfix.exp-post-content.exp-post-content-read-more-underlined p { color: #000 !IMPORTANT; font-size: 20px !important; text-decoration: none !important; } .clearfix.exp-post-content.exp-post-content-read-more-underlined a { color: #000 !IMPORTANT; font-size: 20px !important; text-decoration: none !important; } } /*-----------IPAD------------*/ @media only screen and (min-width: 768px) and (max-width: 1024px){ .no-color.tatsu-column > .tatsu-column-inner { background-color: transparent !important; } .link-white-no-margin.align-center { text-align: center; margin: 0 auto !important; display: block; width: 100% !important; padding-right: 0 !important; } .link-white-no-margin.align-center .circular.mediumbtn { padding: 0 0 20px !important; } h4, .reduce-h4-text { font-size: 2.02em; } .reduce-h6-text { font-size: 14px; } .reduce-h5-text { font-size: 18px; } .overlay-bkgd { background: rgba(0, 0, 0, .2); } .adc-btn-rounded-corner .tatsu-button.rounded{ border-radius: 10px; font-size: 16px; } } /*------------IPHONE PORTRAIT-----------*/ @media only screen and (min-width: 320px) and (max-width: 767px) { .nona-btn.align-center { text-align: center; display: block !important; } .non-gradient-btn.align-center { text-align: center; display: block !important; width: 100%; } .nona-btn.tatsu-button-wrap { display: block !important; } .tatsu-SJbi7CWYO6.tatsu-text-block-wrap { margin: 30px 0px 30px 0px !important; } li.nb-submenu-heading.menu-item a { color: #fff !important; } .pum-theme-read-bio .pum-container { padding: 60px; } input[type="submit"].gform_button, .gform_wrapper.gravity-theme .gform_footer input { padding-top: 8px; padding-bottom: 8px; } } @media only screen and (max-width: 480px) and (min-width: 321px) { } /*------------MDPI LAPTOPS AND UP-----------*/ @media only screen and (min-width: 961px) { .no-color.tatsu-column > .tatsu-column-inner { background-color: transparent !important; } } /*------------FIX MARKETS DIVIDER OVERLAPS ABOVE IPAD-----------*/ @media only screen and (max-width: 767px) { .tatsu-eq-cols>.tatsu-row>.tatsu-column, .tatsu-section .tatsu-eq-cols:last-child>.tatsu-row>.tatsu-column { margin-bottom: 40px !important; } } @media only screen and (min-width: 2000px) { } .gform_wrapper.gravity-theme .gfield input { background-color: #fff; box-shadow: none !important; border-radius: 8px; /* Set the width and style of the border */ border-width: 1px; border-style: solid; /* Create a linear gradient for the border color */ border-image: linear-gradient(to right, #2EA7E0, #1F5690); border-image-slice: 1; /* This property defines the inward offsets of the image-border */ } .gform_wrapper.gravity-theme .gfield textarea { background-color: #fff; border-radius: 8px; box-shadow: none !important; /* Set the width and style of the border */ border-width: 1px; border-style: solid; /* Create a linear gradient for the border color */ border-image: linear-gradient(to right, #2EA7E0, #1F5690); border-image-slice: 1; /* This property defines the inward offsets of the image-border */ } .gform_button.button { border: none !important; background: linear-gradient(to right, #F18E25, #EA5515); transition: all ease-in-out .5s; border-radius: 25px; } .gform_button.button:hover { border: none !important; background: linear-gradient(to right, #FFF, #FFF); color: #000 !important; box-shadow: none !important; } .nona-btn-white a { border: none !important; background: linear-gradient(to right, #fff, #fff); color: #000 !important; transition: all ease-in-out .5s; } .nona-btn-white a:hover { background: linear-gradient(to right, #2EA7E0, #1F5690) !important; color: #fff !important; } .nona-btn a { border: none !important; background: linear-gradient(to right, #F18E25, #EA5515); transition: all ease-in-out .5s; } .nona-btn a:hover { background: linear-gradient(to right, #fff, #fff); color: #000 !important; } .nona-btn .tatsu-button i { margin-right: 0.5em; vertical-align: top; } .nona-btn-white .tatsu-button i { margin-right: 0.5em; vertical-align: top; } /*--.nona-btn.tatsu-button-wrap { display: flex !important; }--*/ .nona-anchor a { border: none !important; } .nona-btn.btn-align-right.tatsu-button-wrap { display: unset !important; clear: both; } .nona-btn.btn-align-right.tatsu-button-wrap .tatsu-button { float: right; } .nona-btn.btn-align-center { float: unset; justify-content: center; } .nona-btn.btn-align-center .circular.mediumbtn { color: #fff; } #show-overflow.tatsu-section { overflow: visible !important; } .tatsu-carousel .flickity-page-dots .dot { width: 13px !important; height: 13px !important; } .flickity-page-dots .is-selected { background-color: #F18E25 !important; } .flickity-page-dots .dot { background: #fff; opacity: 1; top: 25px !important; } .footer-menu-link a { transition: all ease-in-out .5s; font-size: 14px !important; } .footer-menu-link a:hover { color: #F18E25; } .footer-menu-header a { transition: all ease-in-out .5s; font-size: 14px !important; } .footer-menu-header a:hover { color: #F18E25; } .tatsu-gradient-button .tatsu-button-wrap:before { border-style: none !important; border: none !important; } .stuck-content { position: absolute !important; top: 50%; left: 50%; transform: translate(-50%, -50%); z-index: 2; text-align: center; width: 80%; /* Adjust the width as needed */ padding: 20px; background-color: #fff; /* Adjust the background color as needed */ border-radius: 10px; box-shadow: 0 0 10px rgba(0, 0, 0, 0.1); /* Optional: Add a subtle shadow */ } .i-to-i-toggle.tatsu-accordion-style2 .ui-accordion-content-active { border-bottom: none; } .i-to-i-toggle.tatsu-accordion-style2 .accordion-content.ui-accordion-content { padding: 0; margin-bottom: 10px !important; } .i-to-i-toggle .ui-accordion-header-active { color: #fff !important; background-color: #03A9F4; padding-bottom: 0 !important; border-radius: 15px 15px 0 0; } .pum-theme-809 .pum-container, .pum-theme-infographic-2 .pum-container { border-radius: 20px !important; } .clearfix.exp-post-content.exp-post-content-read-more-underlined p { color: #000 !IMPORTANT; font-size: 20px !important; text-decoration: none !important; } .clearfix.exp-post-content.exp-post-content-read-more-underlined a { color: #000 !IMPORTANT; font-size: 20px !important; text-decoration: none !important; } .center-btn.tatsu-button-wrap { display: block !important; } .exp-post-entry-title-wrap { color: #fff !important; } .exp-post-entry-title-wrap h1 { color: #fff !important; } .exp-breadcrumbs { color: #fff !important; } h3.exp-not-found-header-title { color: #fff; } h3.exp-not-found-header-title { color: #fff; } header.exp-not-found-header p { color: #fff; } li.current-menu-item .menu-item-153 a { color: initial !important; } li.current-menu-item .menu-item-154 a { color: initial !important; } li.current-menu-item .menu-item-155 a { color: initial !important; } .page-id-635 .exp-smart-read { color: #fff !important; } .exp-post-password-form-wrap.be-themes-content-padding { padding: 150px 0 !important; color: #fff; } .single-post .be-themes-content-padding.clearfix { background-color: #fff; } .exp-posts-nav { background-color: #DDF1FF !important; } .tatsu-SkmYWXEeQ6.tatsu-menu > ul > li.current-menu-parent > .sub-menu-indicator svg polyline { stroke: #fff !important; } .tatsu-SkmYWXEeQ6.tatsu-menu > ul > li.current-menu-parent > .sub-menu-indicator svg polyline { stroke: #fff !important; } .current-menu-parent.menu-item-has-children.menu-item-24 > a { color: #fff !important; } .current-menu-parent.menu-item-has-children.menu-item-150 > a { color: #fff !important; } .current-menu-parent.menu-item-has-children.menu-item-24 > a:hover { color: #F18E25 !important; } .current-menu-parent.menu-item-has-children.menu-item-150 > a:hover { color: #F18E25 !important; } #corporate-news .insights-corporate .exp-post-title-meta a { color: #fff !important; } p#breadcrumbs { display: none; } #infographic .tatsu-accordion-expand:before { display: none } #infographic .tatsu-accordion-expand:after { height: 0; width: 0; display: none; } #infographic .tatsu-accordion .tatsu-accordion-expand { margin: 0 !important; width: auto !important; } #infographic .tatsu-accordion .accordion-head.ui-accordion-header { align-items: normal; } #infographic .tatsu-accordion .accordion-head.ui-accordion-header span { width: auto; } #infographic h3::after { background: url(/wp-content/uploads/2024/04/down-a.svg); background-repeat: no-repeat; background-size: contain; width: 15px; height: 20px; } span.ui-accordion-header-icon.ui-icon.ui-icon-triangle-1-e::after { background: url(/wp-content/uploads/2024/04/down-a.svg); background-repeat: no-repeat; background-size: contain; width: 6px !important; height: 15px; } #infographic .tatsu-accordion .accordion-head.ui-accordion-header::after { background: url(/wp-content/uploads/2024/04/down-a.svg); background-repeat: no-repeat; background-size: contain; } .exp-post-entry-title-type { display: none; } div#no-hand a { cursor: default !important; } .insights-blog.job-post .exp-post-title a::after { display: none !important; } .insights-blog.job-post .exp-read-more-dots { display: none !important; } textarea { background: #fff !important; border-radius: 10px; border: 1px solid #2EA7E0; } input#first_name { background: #fff !important; border-radius: 10px; border: 1px solid #2EA7E0; } input#last_name { background: #fff !important; border-radius: 10px; border: 1px solid #2EA7E0; } input#email { background: #fff !important; border-radius: 10px; border: 1px solid #2EA7E0; } input#company { background: #fff !important; border-radius: 10px; border: 1px solid #2EA7E0; } label{ font-weight: bold; } </style> <style id="kirki-inline-styles"></style></head> <body class="page-template-default page page-id-1643 wp-custom-logo" data-be-page-template = 'page' > <div id="tatsu-header-container"><div id="tatsu-header-wrap" class=" sticky transparent light header-auto-pad"><div class="tatsu-header default sticky apply-color-scheme tatsu-rJYb7VgQ6 tatsu-hide-tablet tatsu-hide-mobile" data-padding='{"d":"20px 30px 20px 30px","l":"20px 20px 20px 20px"}' data-sticky-padding='{"d":"30"}' ><div class="tatsu-header-row "><div class="tatsu-header-col tatsu-B1etW7Ex7a " ><style>.tatsu-B1etW7Ex7a.tatsu-header-col{flex-basis: 20%;justify-content: flex-start;align-items: center;}.tatsu-B1etW7Ex7a.tatsu-slide-menu-col{justify-content: center;align-items: flex-start;}@media only screen and (max-width:1377px) {.tatsu-B1etW7Ex7a.tatsu-header-col{flex-basis: 10%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-B1etW7Ex7a.tatsu-header-col{flex-basis: 25%;}}@media only screen and (max-width: 767px) {.tatsu-B1etW7Ex7a.tatsu-header-col{flex-basis: 40%;}}</style><div class="tatsu-header-logo tatsu-header-module tatsu-SJbF-QEema " ><a href="https://nonabio.com"><img src="https://nonabio.wpenginepowered.com/wp-content/uploads/2023/12/logo.svg" class="logo-img default-logo" alt="" /><img src="https://nonabio.wpenginepowered.com/wp-content/uploads/2023/12/logo.svg" class="logo-img dark-logo" alt="" /><img src="https://nonabio.wpenginepowered.com/wp-content/uploads/2023/12/logo.svg" class="logo-img light-logo" alt="" /></a><style>.tatsu-SJbF-QEema .logo-img{max-height: 86px;}#tatsu-header-wrap.stuck .tatsu-SJbF-QEema .logo-img{height: 60px;}.tatsu-SJbF-QEema.tatsu-header-logo{margin: 0px 30px 0px 0px;}</style></div></div><div class="tatsu-header-col tatsu-SyGt-QNlmT " ><style>.tatsu-SyGt-QNlmT.tatsu-header-col{flex-basis: 80%;justify-content: flex-end;align-items: center;}.tatsu-SyGt-QNlmT.tatsu-slide-menu-col{justify-content: center;align-items: flex-start;}@media only screen and (max-width:1377px) {.tatsu-SyGt-QNlmT.tatsu-header-col{flex-basis: 90%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-SyGt-QNlmT.tatsu-header-col{flex-basis: 75%;}}@media only screen and (max-width: 767px) {.tatsu-SyGt-QNlmT.tatsu-header-col{flex-basis: 60%;}}</style><nav class="tatsu-header-module tatsu-header-navigation clearfix "><div class="tatsu-menu tatsu-SkmYWXEeQ6"><ul id="normal-menu-SkmYWXEeQ6" class="clearfix "><li class="special-nb-submenu menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children menu-item-22"><a title="Our Company" href="/our-company">Our Company</a> <span class="sub-menu-indicator"><svg xmlns="http://www.w3.org/2000/svg" width="10" height="6" viewBox="0 0 10 6"> <polyline fill="none" stroke="#2F2F30" stroke-linecap="round" stroke-width="2" points="0 .649 3.613 4.127 0 7.604" transform="rotate(90 4 5)"/> </svg> </span><ul class="tatsu-sub-menu clearfix"><span class="tatsu-header-pointer"></span> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-153"><a title="About Us" href="/our-company/#about">About Us</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-155"><a title="Careers" href="/careers/">Careers</a></li> </ul> </li> <li class="special-nb-submenu menu-item menu-item-type-custom menu-item-object-custom current-menu-ancestor menu-item-has-children menu-item-21"><a title="Our Platforms" href="/hcab/#harbour-mice">Our Platforms</a> <span class="sub-menu-indicator"><svg xmlns="http://www.w3.org/2000/svg" width="10" height="6" viewBox="0 0 10 6"> <polyline fill="none" stroke="#2F2F30" stroke-linecap="round" stroke-width="2" points="0 .649 3.613 4.127 0 7.604" transform="rotate(90 4 5)"/> </svg> </span><ul class="tatsu-sub-menu clearfix"><span class="tatsu-header-pointer"></span> <li class="nb-submenu-heading menu-item menu-item-type-custom menu-item-object-custom menu-item-195"><a title="Our Platforms" href="/hcab/#harbour-mice">Our Platforms</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-169"><a title="Harbour Mice® HCAb" href="/hcab/#hcab">Harbour Mice® HCAb</a></li> <li class="menu-item menu-item-type-custom menu-item-object-custom menu-item-173"><a title="Harbour Mice® H2L2" href="/hcab/#h2l2">Harbour Mice® H2L2</a></li> <li class="nb-second-submenu menu-item menu-item-type-custom menu-item-object-custom current-menu-ancestor current-menu-parent menu-item-has-children menu-item-174"><a title="HCAb Plus™" href="/hcab-plus">HCAb Plus™</a> <span class="sub-menu-indicator"><svg xmlns="http://www.w3.org/2000/svg" width="10" height="6" viewBox="0 0 10 6"> <polyline fill="none" stroke="#2F2F30" stroke-linecap="round" stroke-width="2" points="0 .649 3.613 4.127 0 7.604" transform="rotate(90 4 5)"/> </svg> </span><ul class="tatsu-sub-menu clearfix"><span class="tatsu-header-pointer"></span> <li class="menu-item menu-item-type-post_type menu-item-object-page current-menu-item page_item page-item-1643 current_page_item menu-item-1721"><a title="HBICE® - Bi/Multi-specific" href="https://nonabio.com/hbice-bispecific-multispecific/" aria-current="page">HBICE® – Bi/Multi-specific</a></li> <li class="nb-child-submenu-heading menu-item menu-item-type-custom menu-item-object-custom menu-item-176"><a title="CAR-T" href="/car-antibody-discovery/">CAR-T</a></li> <li class="nb-child-submenu-heading menu-item menu-item-type-custom menu-item-object-custom menu-item-177"><a title="ADC" href="https://nonabio.com/adc/">ADC</a></li> <li class="nb-child-submenu-heading menu-item menu-item-type-custom menu-item-object-custom menu-item-178"><a title="mRNA" href="/mrna">mRNA</a></li> </ul> </li> </ul> </li> <li class="special-nb-submenu menu-item menu-item-type-custom menu-item-object-custom menu-item-has-children 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;border-color: #f5f5f5; }#tatsu-header-wrap.transparent.dark:not(.stuck) .tatsu-header.apply-color-scheme .tatsu-Hk8HHrCUa .tatsu-button{color: #232425 ;border-color: #232425; }</style></div><div class="tatsu-header-module tatsu-search tatsu-SkqP-YRcp "> <svg xmlns="http://www.w3.org/2000/svg" width="21" height="21" viewBox="0 0 21 21"> <g fill="none" fill-rule="evenodd" stroke="#212121" stroke-width="2" transform="rotate(-45 9.27 7.257)"> <circle cx="7.846" cy="7.846" r="6.846"/> <path stroke-linecap="round" d="M8.02203654,14.7239099 L8.02203654,23.1736574"/> </g> </svg> <style>.tatsu-SkqP-YRcp.tatsu-search svg g{stroke: #ffffff;}.tatsu-SkqP-YRcp.tatsu-search{margin: 0px 30px 0px 0px;}</style> <div class = "search-bar"> <span class="tatsu-header-pointer"></span> <form role="search" method="get" class="tatsu-search-form" action="https://nonabio.com/" > <input type="text" placeholder="Search ..." value="" name="s" /> </form> </div> <div class = "tatsu-search-bar-overlay"> </div> </div></div></div><style>.tatsu-rJYb7VgQ6.tatsu-header{background-color: rgba(0,21,64,1);}#tatsu-header-wrap.transparent:not(.stuck) .tatsu-header.tatsu-rJYb7VgQ6{background: rgba(255,255,255,0);border-color: rgba(0,0,0,0); }.tatsu-rJYb7VgQ6 .tatsu-header-row{padding: 20px 30px 20px 30px;}#tatsu-header-wrap.stuck .tatsu-rJYb7VgQ6 .tatsu-header-row{padding: 30;}.tatsu-rJYb7VgQ6{border-width: 0px 0px 1px 0px;border-color: rgba(241,142,37,1); border-style: solid;}@media only screen and (max-width:1377px) {.tatsu-rJYb7VgQ6 .tatsu-header-row{padding: 20px 20px 20px 20px;}}</style></div><div class="tatsu-header default sticky apply-color-scheme tatsu-rygcLVem6 tatsu-hide-laptop tatsu-hide-desktop" data-padding='{"d":"20px 30px 20px 30px","m":"20px 10px 20px 10px"}' data-sticky-padding='{"d":"30"}' ><div class="tatsu-header-row "><div class="tatsu-header-col tatsu-H1x5sObcL6 " ><style>.tatsu-H1x5sObcL6.tatsu-header-col{flex-basis: 50%;justify-content: flex-end;align-items: center;}.tatsu-H1x5sObcL6.tatsu-slide-menu-col{justify-content: center;align-items: flex-start;}@media only screen and (max-width:1377px) {.tatsu-H1x5sObcL6.tatsu-header-col{flex-basis: 50%;justify-content: flex-end;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-H1x5sObcL6.tatsu-header-col{flex-basis: 50%;justify-content: flex-start;}}@media only screen and (max-width: 767px) {.tatsu-H1x5sObcL6.tatsu-header-col{flex-basis: 80%;justify-content: flex-start;}}</style><div class="tatsu-header-logo tatsu-header-module tatsu-SyWhub9IT " ><a href="https://nonabio.com"><img src="https://nonabio.wpenginepowered.com/wp-content/uploads/2023/12/logo.svg" class="logo-img default-logo" alt="" /><img src="https://nonabio.wpenginepowered.com/wp-content/uploads/2023/12/logo.svg" class="logo-img dark-logo" alt="" /><img src="https://nonabio.wpenginepowered.com/wp-content/uploads/2023/12/logo.svg" class="logo-img light-logo" alt="" /></a><style>.tatsu-SyWhub9IT .logo-img{max-height: 30px;}#tatsu-header-wrap.stuck .tatsu-SyWhub9IT .logo-img{height: 30px;}.tatsu-SyWhub9IT.tatsu-header-logo{margin: 0px 30px 0px 0px;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-SyWhub9IT .logo-img{max-height: 87px;}}@media only screen and (max-width: 767px) {.tatsu-SyWhub9IT .logo-img{max-height: 75px;}#tatsu-header-wrap.stuck .tatsu-SyWhub9IT .logo-img{height: 75px;}.tatsu-SyWhub9IT.tatsu-header-logo{margin: 0px 0px 0px 0px;}}</style></div></div><div class="tatsu-header-col tatsu-rJllqLVl76 " ><style>.tatsu-rJllqLVl76.tatsu-header-col{flex-basis: 50%;justify-content: flex-end;align-items: center;}.tatsu-rJllqLVl76.tatsu-slide-menu-col{justify-content: center;align-items: flex-start;}@media only screen and (max-width:1377px) {.tatsu-rJllqLVl76.tatsu-header-col{flex-basis: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-rJllqLVl76.tatsu-header-col{flex-basis: 50%;}}@media only screen and (max-width: 767px) {.tatsu-rJllqLVl76.tatsu-header-col{flex-basis: 20%;}}</style><div class="tatsu-header-module tatsu-hamburger tatsu-S1fFyOElXT " data-slide-menu="tatsu-S1fFyOElXT"> <style>.tatsu-S1fFyOElXT.tatsu-hamburger span{background-color: rgba(255,255,255,1);width: 37px;}#tatsu-S1fFyOElXT.tatsu-slide-menu{background-color: rgba(1,36,78,1);}.tatsu-S1fFyOElXT.tatsu-hamburger{margin: 0px 30px 0px 0px;}@media only screen and (max-width: 767px) {#tatsu-S1fFyOElXT.tatsu-slide-menu{width: 310px;transform: translateX(310px);}}</style> <div class="line-wrapper"> <span class="line-1"></span> <span class="line-2"></span> <span class="line-3"></span> </div> </div></div></div><style>.tatsu-rygcLVem6.tatsu-header{background-color: rgba(0,21,64,1);}#tatsu-header-wrap.transparent:not(.stuck) .tatsu-header.tatsu-rygcLVem6{background: rgba(0,0,0,0);border-color: rgba(0,0,0,0); }.tatsu-rygcLVem6 .tatsu-header-row{padding: 20px 30px 20px 30px;}#tatsu-header-wrap.stuck .tatsu-rygcLVem6 .tatsu-header-row{padding: 30;}.tatsu-rygcLVem6{border-width: 0px 0px 1px 0px;border-color: rgba(241,142,37,1); border-style: solid;}@media only screen and (max-width: 767px) {.tatsu-rygcLVem6 .tatsu-header-row{padding: 20px 10px 20px 10px;}}</style></div></div><div id="tatsu-header-placeholder"></div></div> <div id="be-content"> <div class="tatsu-Hy2Ny0cqp tatsu-section tatsu-bg-overlay tatsu-clearfix" data-title="" data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"100px 0px 202px 0px","m":"50px 0px 36px 0px"}' data-padding-top='50px'><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-SJx3V1A996" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-H1W2NJRq5a" data-animation="fadeInUp" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-HJe-SbJFR "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-HJe-SbJFR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: center;}</style> <h5>HCAb Plus™</h5> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-r1X3V1Aqc6 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-r1X3V1Aqc6.tatsu-text-block-wrap .tatsu-text-inner{width: 86%;text-align: center;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-r1X3V1Aqc6.tatsu-text-block-wrap .tatsu-text-inner{width: 60%;}}@media only screen and (max-width: 767px) {.tatsu-r1X3V1Aqc6.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-r1X3V1Aqc6.tatsu-text-block-wrap{margin: 0px 0px 10px 0px;}}</style> <div class="tatsu-column-pad-wrap"> <div class="tatsu-column-pad"> <div class="tatsu-module tatsu-text-block-wrap tatsu-r1X3V1Aqc6 "> <div class="tatsu-text-inner tatsu-align-center clearfix"> <h1 class="white-text">HBICE® TCE:</h1> <h1 class="white-text">Bi/Multi-Specific T Cell Engagers in Immunotherapy</h1> </div> </div> </div> </div> <div class="tatsu-column-bg-image-wrap"> </div> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-H1W2NJRq5a.tatsu-column{width: 100%;}.tatsu-H1W2NJRq5a.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-H1W2NJRq5a > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-H1W2NJRq5a > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-H1W2NJRq5a > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-H1W2NJRq5a > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-H1W2NJRq5a.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-H1W2NJRq5a.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-H1W2NJRq5a.tatsu-column{width: 100%;}}</style></div></div></div></div><div class="tatsu-section-background-wrap"><div class = "tatsu-section-background" ></div></div><div class="tatsu-overlay tatsu-section-overlay"></div><style>.tatsu-Hy2Ny0cqp.tatsu-section{background-color: rgba(0,21,64,1);}.tatsu-Hy2Ny0cqp .tatsu-section-background{background-image: url(https://nonabio.wpenginepowered.com/wp-content/uploads/2024/01/adc-hero.svg);background-repeat: no-repeat;background-attachment: scroll;background-position: center right;background-size: cover;}.tatsu-Hy2Ny0cqp .tatsu-bg-blur{background-repeat: no-repeat;background-attachment: scroll;background-position: center right;background-size: cover;}.tatsu-Hy2Ny0cqp .tatsu-section-pad{padding: 100px 0px 202px 0px;}.tatsu-Hy2Ny0cqp .tatsu-section-offset-wrap{transform: translateY(-0px);}.tatsu-Hy2Ny0cqp > .tatsu-bottom-divider{z-index: 9999;}.tatsu-Hy2Ny0cqp > .tatsu-top-divider{z-index: 9999;}.tatsu-Hy2Ny0cqp .tatsu-section-overlay{mix-blend-mode: normal;}@media only screen and (max-width: 767px) {.tatsu-Hy2Ny0cqp .tatsu-section-background{background-position: top right;}.tatsu-Hy2Ny0cqp .tatsu-bg-blur{background-position: top right;}.tatsu-Hy2Ny0cqp .tatsu-section-pad{padding: 50px 0px 36px 0px;}}</style></div><div class="tatsu-r1_injLY0 tatsu-section tatsu-bg-overlay tatsu-clearfix" data-title="Section 1" data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"113px 0px 70px 0px","m":"43px 0px 70px 0px"}' data-padding-top='43px'><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-Hyxui3jLt0" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-column-image-none tatsu-column-effect-none tatsu-SJ-ui3jLKA" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-Hkf_ohsUKA "><div class="tatsu-text-inner tatsu-align-center tatsu-animate clearfix" data-animation="fadeInLeft" data-animation-duration="1280"><style>.tatsu-Hkf_ohsUKA.tatsu-text-block-wrap .tatsu-text-inner{width: 73%;text-align: center;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-Hkf_ohsUKA.tatsu-text-block-wrap .tatsu-text-inner{text-align: center;}}@media only screen and (max-width: 767px) {.tatsu-Hkf_ohsUKA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-Hkf_ohsUKA.tatsu-text-block-wrap{margin: 0px 0px 20px 0px;}}</style> <h3 class="blue-text">HCAb-Based Immune Cell Engager</h3> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HyQds2oLKA "><div class="tatsu-text-inner tatsu-align-center tatsu-animate clearfix" data-animation="fadeInLeft" data-animation-delay="300" data-animation-duration="1280"><style>.tatsu-HyQds2oLKA.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;}.tatsu-HyQds2oLKA.tatsu-text-block-wrap{margin: 0px 0px 50px 0px;}@media only screen and (max-width: 767px) {.tatsu-HyQds2oLKA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;}.tatsu-HyQds2oLKA.tatsu-text-block-wrap{margin: 0px 0px 30px 0px;}}</style> <p>HCAb-Based Immune Cell Engagers (HBICE®) are advanced T Cell Engagers (TCEs) developed by Nona Biosciences to enhance the immune system’s ability to target and eliminate cancer cells by directly linking T cells to tumor cells. These bispecific and multispecific antibodies target both a pan T cell marker (often CD3) and tumor-associated antigens (TAAs), promoting T cell activation and precise tumor lysis through the formation of an immunologic synapse.</p> </div></div><div class="tatsu-single-image tatsu-module align-center tatsu-image-lazyload tatsu-HJDOj2jLK0 tatsu-hide-mobile" ><div class="tatsu-single-image-inner " style="width : 2890px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 64.9826989619%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "HBICE" data-src = "https://nonabio.com/wp-content/uploads/2024/08/HBICE-1.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-HJDOj2jLK0 .tatsu-single-image-inner{border-style: solid;max-width: 87%;}.tatsu-HJDOj2jLK0.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (max-width: 767px) {.tatsu-HJDOj2jLK0 .tatsu-single-image-inner{max-width: 100%;}}</style></div><div class="tatsu-single-image tatsu-module align-center tatsu-image-lazyload tatsu-rJkfPgxq0 tatsu-hide-tablet tatsu-hide-laptop tatsu-hide-desktop" ><div class="tatsu-single-image-inner " style="width : 1909px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 126.925091671%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "HBICE2" data-src = "https://nonabio.com/wp-content/uploads/2024/08/HBICE2.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-rJkfPgxq0 .tatsu-single-image-inner{border-style: solid;max-width: 87%;}.tatsu-rJkfPgxq0.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (max-width: 767px) {.tatsu-rJkfPgxq0 .tatsu-single-image-inner{max-width: 100%;}}</style></div><div class="tatsu-module tatsu-text-block-wrap tatsu-S1Lui2jLFA "><div class="tatsu-text-inner tatsu-align-center tatsu-animate clearfix" data-animation="fadeInLeft" data-animation-delay="300" data-animation-duration="1280"><style>.tatsu-S1Lui2jLFA.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: center;color: rgba(1,36,78,1) ;}.tatsu-S1Lui2jLFA.tatsu-text-block-wrap{margin: 0px 0px 20px 0px;}.tatsu-S1Lui2jLFA .tatsu-text-inner *{color: rgba(1,36,78,1) ;}@media only screen and (max-width: 767px) {.tatsu-S1Lui2jLFA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-S1Lui2jLFA.tatsu-text-block-wrap{margin: 0px 0px 30px 0px;}}</style> <p>Figure 1: Novel HBICE®</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-SJ-ui3jLKA.tatsu-column{width: 100%;}.tatsu-SJ-ui3jLKA.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-SJ-ui3jLKA > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-SJ-ui3jLKA > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-SJ-ui3jLKA > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-SJ-ui3jLKA > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-SJ-ui3jLKA.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-SJ-ui3jLKA.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-SJ-ui3jLKA.tatsu-column{width: 100%;}}</style></div></div></div></div><div class="tatsu-section-background-wrap"><div class = "tatsu-section-background" ></div></div><div class="tatsu-overlay tatsu-section-overlay"></div><style>.tatsu-r1_injLY0.tatsu-section{background-color: rgba(221,241,255,1);}.tatsu-r1_injLY0 .tatsu-section-pad{padding: 113px 0px 70px 0px;}.tatsu-r1_injLY0 .tatsu-section-offset-wrap{transform: translateY(-0px);}.tatsu-r1_injLY0 > .tatsu-bottom-divider{z-index: 9999;}.tatsu-r1_injLY0 > .tatsu-top-divider{z-index: 9999;}.tatsu-r1_injLY0 .tatsu-section-overlay{mix-blend-mode: normal;}@media only screen and (max-width: 767px) {.tatsu-r1_injLY0 .tatsu-section-pad{padding: 43px 0px 70px 0px;}}</style></div><div id="beacon-technology" class="tatsu-BJGx6lJAx5T tatsu-section tatsu-bg-overlay tatsu-clearfix" data-title="Section 2 " data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"91px 0px 50px 0px","l":"67px 0px 50px 0px","t":"64px 0px 50px 0px","m":"33px 0px 20px 0px"}' data-padding-top='33px'><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-hide-tablet tatsu-hide-mobile tatsu-clearfix tatsu-BJme6gk0e5p" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-BkNeaekAeqp" data-animation="fadeInLeft" data-animation-delay="300" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-rkalwSs5a tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-tablet tatsu-hide-mobile "><div class="tatsu-text-inner tatsu-align-right clearfix" ><style>.tatsu-rkalwSs5a.tatsu-text-block-wrap .tatsu-text-inner{width: 75%;text-align: left;color: #ffffff ;}.tatsu-rkalwSs5a.tatsu-text-block-wrap{margin: 40px 0px 30px 0px;}.tatsu-rkalwSs5a .tatsu-text-inner *{color: #ffffff ;}@media only screen and (max-width:1377px) {.tatsu-rkalwSs5a.tatsu-text-block-wrap{margin: 20px 0px 10px 0px;}}@media only screen and (max-width: 767px) {.tatsu-rkalwSs5a.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <h4 style="text-align: left;">Introduction</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-rkSOonjLK0 "><div class="tatsu-text-inner tatsu-align-center tatsu-animate clearfix" data-animation="fadeInLeft" data-animation-delay="300" data-animation-duration="1280"><style>.tatsu-rkSOonjLK0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: #ffffff ;}.tatsu-rkSOonjLK0.tatsu-text-block-wrap{margin: 0px 0px 52px 0px;}.tatsu-rkSOonjLK0 .tatsu-text-inner *{color: #ffffff ;}@media only screen and (max-width: 767px) {.tatsu-rkSOonjLK0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;}}</style> <p><span style="font-weight: 400;">The diagrams below depict illustrative scenarios: by circumventing the conventional T-cell activation pathway, typically mediated by the TCR-MHC interaction, HBICE® molecules with CD3-targeting capabilities can induce a broad T-cell response that is not restricted by MHC, effectively overcoming immune escape mechanisms like antigen presentation downregulation. Within the tumor microenvironment (TME), T cells often lack essential costimulatory signals for optimal functionality. HBICE® antibodies, designed to target tumor-associated antigens (TAAs) and provide the essential costimulatory signal for full T cell activation in TAA-dependent manner. This mechanism results in the effective eradication of tumors and an enhanced safety profile.</span></p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-BkNeaekAeqp.tatsu-column{width: 100%;}.tatsu-BkNeaekAeqp.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-BkNeaekAeqp > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-BkNeaekAeqp > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-BkNeaekAeqp > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-BkNeaekAeqp > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-BkNeaekAeqp.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-BkNeaekAeqp.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-BkNeaekAeqp.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-one-half tatsu-row-has-two-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-H1rpEZyF0" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-HylB6Eb1KA" data-animation="fadeInLeft" data-animation-delay="300" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-Byq_jnoLYR img-rounded-corner " data-animation="fadeInLeft" data-animation-delay="600" data-animation-duration="1280"><div class="tatsu-single-image-inner " style="width : 2070px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 69.4202898551%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "HBICE MOA1" data-src = "https://nonabio.com/wp-content/uploads/2024/08/HBICE-MOA1.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-Byq_jnoLYR{margin: 10px 0px 10px 0px;}.tatsu-Byq_jnoLYR .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-Byq_jnoLYR.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (max-width: 767px) {.tatsu-Byq_jnoLYR{margin: 0px 0px 10px 0px;}}</style></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap align-block block-center tatsu-r18hEBy_K0 non-gradient-btn align-center"><a class="tatsu-shortcode x-largebtn tatsu-button left-icon circular tatsu-animate bg-animation-none " href="#HBICE MOA 1" style= "" data-animation="fadeInDown" data-animation-delay="300" data-animation-duration="700" aria-label="HBICE® MOA 1" data-gdpr-atts={} >HBICE® MOA 1</a><style>.tatsu-r18hEBy_K0 .tatsu-button{background-color: rgba(241,142,37,1);color: #ffffff ;}.tatsu-r18hEBy_K0{padding: 15px 0px 0px 0px;}@media only screen and (max-width: 767px) {.tatsu-r18hEBy_K0{padding: 0px 0px 25px 0px;}}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-HylB6Eb1KA.tatsu-column{width: 49.2%;}.tatsu-HylB6Eb1KA.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-HylB6Eb1KA > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-HylB6Eb1KA > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-HylB6Eb1KA > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-HylB6Eb1KA > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-HylB6Eb1KA.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-HylB6Eb1KA.tatsu-column{width: 50%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-HylB6Eb1KA.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-column-image-none tatsu-column-effect-none tatsu-SJmraE-1YR" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-rkT_jnjUFC img-rounded-corner " data-animation="fadeInLeft" data-animation-delay="600" data-animation-duration="1280"><div class="tatsu-single-image-inner " style="width : 2088px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 69.7318007663%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "HBICE MOA2" data-src = "https://nonabio.com/wp-content/uploads/2024/07/HBICE-MOA2-1.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-rkT_jnjUFC{margin: 0px 0px 10px 0px;}.tatsu-rkT_jnjUFC .tatsu-single-image-inner{border-style: none;border-width: 2px;border-image: linear-gradient(90deg, rgba(241,142,37,1) 0%, rgba(235,88,22,1) 100%);border-image-slice: 1;max-width: 100%;border-radius: 10px;}.tatsu-rkT_jnjUFC.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (max-width: 767px) {.tatsu-rkT_jnjUFC{margin: 0px 0px 20px 0px;}}</style></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap align-block block-center tatsu-S1X1LJOFC non-gradient-btn align-center"><a class="tatsu-shortcode x-largebtn tatsu-button left-icon circular tatsu-animate bg-animation-none " href="#HBICE MOA 2" style= "" data-animation="fadeInDown" data-animation-delay="300" data-animation-duration="700" aria-label="HBICE® MOA 2" data-gdpr-atts={} >HBICE® MOA 2</a><style>.tatsu-S1X1LJOFC .tatsu-button{background-color: rgba(238,119,31,1);color: #ffffff ;}.tatsu-S1X1LJOFC{padding: 15px 0px 0px 0px;}@media only screen and (max-width: 767px) {.tatsu-S1X1LJOFC{padding: 0px 0px 25px 0px;}}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-SJmraE-1YR.tatsu-column{width: 50.8%;}.tatsu-SJmraE-1YR.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-SJmraE-1YR > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-SJmraE-1YR > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-SJmraE-1YR > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-SJmraE-1YR > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-SJmraE-1YR.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-SJmraE-1YR.tatsu-column{width: 50%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-SJmraE-1YR.tatsu-column{width: 100%;}}</style></div></div></div></div><div class="tatsu-section-background-wrap"><div class = "tatsu-section-background" ></div></div><div class="tatsu-overlay tatsu-section-overlay"></div><style>.tatsu-BJGx6lJAx5T.tatsu-section{background-color: rgba(1,36,78,1);}.tatsu-BJGx6lJAx5T .tatsu-section-pad{padding: 91px 0px 50px 0px;}.tatsu-BJGx6lJAx5T .tatsu-section-offset-wrap{transform: translateY(-0px);}.tatsu-BJGx6lJAx5T > .tatsu-bottom-divider{z-index: 9999;}.tatsu-BJGx6lJAx5T > .tatsu-top-divider{z-index: 9999;}.tatsu-BJGx6lJAx5T .tatsu-section-overlay{background: rgba(0,21,64,1);mix-blend-mode: normal;}@media only screen and (max-width:1377px) {.tatsu-BJGx6lJAx5T .tatsu-section-pad{padding: 67px 0px 50px 0px;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-BJGx6lJAx5T .tatsu-section-pad{padding: 64px 0px 50px 0px;}}@media only screen and (max-width: 767px) {.tatsu-BJGx6lJAx5T .tatsu-section-pad{padding: 33px 0px 20px 0px;}}</style></div><div id="HBICE MOA 1" class="tatsu-S1XM-cSdA tatsu-section tatsu-bg-overlay tatsu-clearfix" data-title="" data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"106px 0px 50px 0px","l":"64px 0px 45px 0px","t":"46px 0px 50px 0px","m":"35px 0px 20px 0px"}' data-padding-top='35px'><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-two-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-SJx7zZ5H_R" ><style>.tatsu-SJx7zZ5H_R.tatsu-row-wrap > .tatsu-row{padding: 0px 0px 13px 0px;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-SJx7zZ5H_R.tatsu-row-wrap > .tatsu-row{padding: 0px 0px 0px 0px;}}@media only screen and (max-width: 767px) {.tatsu-SJx7zZ5H_R.tatsu-row-wrap > .tatsu-row{padding: 0px 0px 0px 0px;}}</style><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-two-third tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-r1WQfb9H_0" data-animation="fadeInLeft" data-animation-delay="300" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-SJ2LErutC "><div class="tatsu-text-inner clearfix" ><style>.tatsu-SJ2LErutC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(238,119,31,1) ;}.tatsu-SJ2LErutC.tatsu-text-block-wrap{margin: 0px 0px 10px 0px;}.tatsu-SJ2LErutC .tatsu-text-inner *{color: rgba(238,119,31,1) ;}</style> <h5 style="text-align: left;"><strong>HBICE® MOA 1 (CD3 targeting)<br /></strong></h5> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HJM7MW9rOA "><div class="tatsu-text-inner clearfix" ><style>.tatsu-HJM7MW9rOA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;}.tatsu-HJM7MW9rOA.tatsu-text-block-wrap{margin: 0px 0px 20px 0px;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-HJM7MW9rOA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-HJM7MW9rOA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-HJM7MW9rOA.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}}</style> <h4 style="text-align: left;">Driving Innovation in Cancer Immunotherapy by T-Cell Engager</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-r1Q7z-5BOC "><div class="tatsu-text-inner clearfix" ><style>.tatsu-r1Q7z-5BOC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(255,255,255,1) ;}.tatsu-r1Q7z-5BOC.tatsu-text-block-wrap{margin: 30px 0px 0px 0px;}.tatsu-r1Q7z-5BOC .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (max-width:1377px) {.tatsu-r1Q7z-5BOC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-r1Q7z-5BOC.tatsu-text-block-wrap .tatsu-text-inner{text-align: center;}}@media only screen and (max-width: 767px) {.tatsu-r1Q7z-5BOC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <p style="text-align: left;">T-cell engagers are bispecific antibodies designed to simultaneously bind to the antigens on target cells and CD3 receptors on T-cells. This dual binding brings T-cells into proximity with the target cells, activating the T-cells to attack and eliminate the target cells.</p> <p>Nona Biosciences’ T-cell engager technology, powered by the HBICE® platform, offers a promising approach for the treatments of cancer and other indications.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-r1WQfb9H_0.tatsu-column{width: 65.3%;}.tatsu-r1WQfb9H_0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-r1WQfb9H_0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-r1WQfb9H_0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-r1WQfb9H_0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-r1WQfb9H_0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-r1WQfb9H_0.tatsu-column{width: 52.6%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-r1WQfb9H_0.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-r1WQfb9H_0.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-third tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-rke5CWw3uR" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-SkUyMDhdC " data-animation="fadeInLeft" ><div class="tatsu-single-image-inner " style="width : 1226px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 104.323001631%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "T-cell engagers" data-src = "https://nonabio.com/wp-content/uploads/2024/08/T-cell-engagers.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-SkUyMDhdC .tatsu-single-image-inner{border-style: none;border-width: 8px;border-color: rgba(221,241,255,1); max-width: 100%;border-radius: 10px;}.tatsu-SkUyMDhdC.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (max-width:1377px) {.tatsu-SkUyMDhdC .tatsu-single-image-inner{border-style: none;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-SkUyMDhdC .tatsu-single-image-inner{max-width: 50%;}}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-rke5CWw3uR.tatsu-column{width: 34.7%;}.tatsu-rke5CWw3uR.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-rke5CWw3uR > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-rke5CWw3uR > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-rke5CWw3uR > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-rke5CWw3uR > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-rke5CWw3uR.tatsu-column{width: 40.67%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-rke5CWw3uR.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-rke5CWw3uR.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-HJxV2VedFR" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-column-image-none tatsu-column-effect-none tatsu-rkV24x_tA" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-rkblk4o0C_R "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-rkblk4o0C_R.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 40px 40px 40px 40px;color: rgba(255,255,255,1) ;}.tatsu-rkblk4o0C_R.tatsu-text-block-wrap{margin: 20px 0px 0px 0px;}.tatsu-rkblk4o0C_R .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-rkblk4o0C_R.tatsu-text-block-wrap .tatsu-text-inner{text-align: center;padding: 30px 30px 30px 30px;}}@media only screen and (max-width: 767px) {.tatsu-rkblk4o0C_R.tatsu-text-block-wrap .tatsu-text-inner{text-align: left;padding: 25px 25px 25px 25px;}}</style> <h4>Advantages of T-Cell Engagers</h4> <p>T-cell engagers bridge T-cells and target cells, unleashing targeted immune responses. Key benefits include:</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-rkV24x_tA.tatsu-column{width: 100%;}.tatsu-rkV24x_tA.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-rkV24x_tA > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-rkV24x_tA > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-rkV24x_tA > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-rkV24x_tA > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-rkV24x_tA.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-rkV24x_tA.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-rkV24x_tA.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-one-half tatsu-row-has-two-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-r1xkLSnLKC" ><style>@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-r1xkLSnLKC.tatsu-row-wrap > .tatsu-row{padding: 0px 0px 0px 18px;}}</style><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-column-image-none tatsu-column-effect-none tatsu-Skk8HnLF0" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-SywVdJnUYC "><div class="tatsu-text-inner clearfix" ><style>.tatsu-SywVdJnUYC.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;color: rgba(238,119,31,1) ;}.tatsu-SywVdJnUYC.tatsu-text-block-wrap{margin: 0px 0px 15px 0px;}.tatsu-SywVdJnUYC .tatsu-text-inner *{color: rgba(238,119,31,1) ;}@media only screen and (max-width:1377px) {.tatsu-SywVdJnUYC.tatsu-text-block-wrap{margin: 0px 0px 10px 0px;}}@media only screen and (max-width: 767px) {.tatsu-SywVdJnUYC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <ul> <li> <h5><strong>Precision Targeting</strong>:</h5> </li> </ul> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HydVuy28K0 "><div class="tatsu-text-inner clearfix" ><style>.tatsu-HydVuy28K0.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;color: rgba(255,255,255,1) ;}.tatsu-HydVuy28K0 .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (max-width:1377px) {.tatsu-HydVuy28K0.tatsu-text-block-wrap .tatsu-text-inner{padding: 0px 0px 0px 20px;}}@media only screen and (max-width: 767px) {.tatsu-HydVuy28K0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <p>Direct T-cells to specific target cells, minimizing off-target effects.</p> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HkRhHnUK0 "><div class="tatsu-text-inner clearfix" ><style>.tatsu-HkRhHnUK0.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;color: rgba(238,119,31,1) ;}.tatsu-HkRhHnUK0.tatsu-text-block-wrap{margin: 0px 0px 15px 0px;}.tatsu-HkRhHnUK0 .tatsu-text-inner *{color: rgba(238,119,31,1) ;}@media only screen and (max-width:1377px) {.tatsu-HkRhHnUK0.tatsu-text-block-wrap{margin: 0px 0px 10px 0px;}}@media only screen and (max-width: 767px) {.tatsu-HkRhHnUK0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <ul> <li> <h5><strong>Enhanced Efficacy</strong>:</h5> </li> </ul> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-rkXx8hIYA "><div class="tatsu-text-inner clearfix" ><style>.tatsu-rkXx8hIYA.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;color: rgba(255,255,255,1) ;}.tatsu-rkXx8hIYA .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (max-width:1377px) {.tatsu-rkXx8hIYA.tatsu-text-block-wrap .tatsu-text-inner{padding: 0px 0px 0px 20px;}}@media only screen and (max-width: 767px) {.tatsu-rkXx8hIYA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <p>Demonstrated clinical efficacy in hematological malignancies and solid tumors, with potential applications in non-oncology indications.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-Skk8HnLF0.tatsu-column{width: 50%;}.tatsu-Skk8HnLF0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-Skk8HnLF0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-Skk8HnLF0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-Skk8HnLF0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-Skk8HnLF0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-Skk8HnLF0.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-Skk8HnLF0.tatsu-column{width: 50%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-Skk8HnLF0.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-column-image-none tatsu-column-effect-none tatsu-S1x_cElut0" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-HJyxI3UKR "><div class="tatsu-text-inner clearfix" ><style>.tatsu-HJyxI3UKR.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;color: rgba(238,119,31,1) ;}.tatsu-HJyxI3UKR.tatsu-text-block-wrap{margin: 0px 0px 15px 0px;}.tatsu-HJyxI3UKR .tatsu-text-inner *{color: rgba(238,119,31,1) ;}@media only screen and (max-width:1377px) {.tatsu-HJyxI3UKR.tatsu-text-block-wrap{margin: 0px 0px 10px 0px;}}@media only screen and (max-width: 767px) {.tatsu-HJyxI3UKR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <ul> <li> <h5><strong>Versatile Formats</strong>:</h5> </li> </ul> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-S1FaHh8FC "><div class="tatsu-text-inner clearfix" ><style>.tatsu-S1FaHh8FC.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;color: rgba(255,255,255,1) ;}.tatsu-S1FaHh8FC .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (max-width:1377px) {.tatsu-S1FaHh8FC.tatsu-text-block-wrap .tatsu-text-inner{padding: 0px 0px 0px 20px;}}@media only screen and (max-width: 767px) {.tatsu-S1FaHh8FC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <p>Flexible geometries for different therapeutic needs, including bi- and multi-specific formats.</p> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-By0Z8nUtR "><div class="tatsu-text-inner clearfix" ><style>.tatsu-By0Z8nUtR.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;color: rgba(238,119,31,1) ;}.tatsu-By0Z8nUtR.tatsu-text-block-wrap{margin: 0px 0px 15px 0px;}.tatsu-By0Z8nUtR .tatsu-text-inner *{color: rgba(238,119,31,1) ;}@media only screen and (max-width:1377px) {.tatsu-By0Z8nUtR.tatsu-text-block-wrap{margin: 0px 0px 10px 0px;}}@media only screen and (max-width: 767px) {.tatsu-By0Z8nUtR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <ul> <li> <h5><strong>Safety Profile</strong>:</h5> </li> </ul> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HymfI3UFR "><div class="tatsu-text-inner clearfix" ><style>.tatsu-HymfI3UFR.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;color: rgba(255,255,255,1) ;}.tatsu-HymfI3UFR .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (max-width:1377px) {.tatsu-HymfI3UFR.tatsu-text-block-wrap .tatsu-text-inner{padding: 0px 0px 0px 20px;}}@media only screen and (max-width: 767px) {.tatsu-HymfI3UFR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <p>Optimized to balance cytotoxicity and cytokine release, reducing adverse effects.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-S1x_cElut0.tatsu-column{width: 50%;}.tatsu-S1x_cElut0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-S1x_cElut0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-S1x_cElut0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-S1x_cElut0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-S1x_cElut0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-S1x_cElut0.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-S1x_cElut0.tatsu-column{width: 50%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-S1x_cElut0.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-one-half tatsu-row-has-two-cols tatsu-custom-gutter tatsu-reg-cols tatsu-swap-cols tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-tablet tatsu-hide-mobile tatsu-clearfix tatsu-rk47Gb5ru0" ><style>.tatsu-rk47Gb5ru0.tatsu-row-wrap > .tatsu-row{padding: 60px 0px 60px 0px;}@media only screen and (max-width: 767px) {.tatsu-rk47Gb5ru0.tatsu-row-wrap > .tatsu-row{padding: 30px 0px 30px 0px;}}</style><div class="tatsu-row " style="margin-left:-71px;margin-right:-71px;"><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-animate tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-SkSQz-9rOR" data-animation="fadeInLeft" data-parallax-speed="0" style=" padding:0 71px;"><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-rkU7zZqBdA "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-rkU7zZqBdA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;}</style> <h4 class="white-text">High Throughput Chip</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-ByvmzZcHdC "><div class="tatsu-text-inner clearfix" ><style>.tatsu-ByvmzZcHdC.tatsu-text-block-wrap .tatsu-text-inner{width: 78%;text-align: left;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-ByvmzZcHdC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-ByvmzZcHdC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <p class="white-text body2">Each 20K OptoSelect chip has 20,000 individual NanoPen chambers and can separate and screen up to 20,000 cells within a single run.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-SkSQz-9rOR.tatsu-column{width: 50%;}.tatsu-SkSQz-9rOR.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0% 5% 10% 0%;}.tatsu-SkSQz-9rOR.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-SkSQz-9rOR > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-SkSQz-9rOR > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-SkSQz-9rOR > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-SkSQz-9rOR > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-SkSQz-9rOR.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-SkSQz-9rOR.tatsu-column{width: 50%;}.tatsu-SkSQz-9rOR.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0% 1% 10% 3%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-SkSQz-9rOR.tatsu-column{width: 100%;}.tatsu-SkSQz-9rOR.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0% 5% 4% 0%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-column-image-none tatsu-column-effect-none tatsu-BkdmGZ5H_C" data-parallax-speed="0" style=" padding:0 71px;"><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-image-lazyload tatsu-external-image tatsu-HkKmGWqSdA " ><div class="tatsu-single-image-inner " style="" ><div class = "tatsu-single-image-padding-wrap" style = "" ></div><img class = "tatsu-gradient-border" data-src = "https://nonabio.wpenginepowered.com/wp-content/uploads/2024/01/high-throughput-chip.svg" alt =" " src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-HkKmGWqSdA .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-HkKmGWqSdA.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-BkdmGZ5H_C.tatsu-column{width: 50%;}.tatsu-BkdmGZ5H_C.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-BkdmGZ5H_C > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-BkdmGZ5H_C > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-BkdmGZ5H_C > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-BkdmGZ5H_C > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-BkdmGZ5H_C.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-BkdmGZ5H_C.tatsu-column{width: 50%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-BkdmGZ5H_C.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-one-half tatsu-row-has-two-cols tatsu-custom-gutter tatsu-reg-cols tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-tablet tatsu-hide-mobile tatsu-clearfix tatsu-B1c7Mb5Hd0" ><style>.tatsu-B1c7Mb5Hd0.tatsu-row-wrap > .tatsu-row{padding: 90px 0px 60px 0px;}@media only screen and (max-width: 767px) {.tatsu-B1c7Mb5Hd0.tatsu-row-wrap > .tatsu-row{padding: 30px 0px 30px 0px;}}</style><div class="tatsu-row " style="margin-left:-71px;margin-right:-71px;"><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-animate tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-SyoXz-qrdR" data-animation="fadeInLeft" data-parallax-speed="0" style=" padding:0 71px;"><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-image-lazyload tatsu-external-image tatsu-Syhmf-cruC " ><div class="tatsu-single-image-inner " style="" ><div class = "tatsu-single-image-padding-wrap" style = "" ></div><img class = "tatsu-gradient-border" data-src = "https://nonabio.wpenginepowered.com/wp-content/uploads/2024/01/in-chip-assays.svg" alt =" " src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-Syhmf-cruC .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-Syhmf-cruC.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-SyoXz-qrdR.tatsu-column{width: 35%;}.tatsu-SyoXz-qrdR.tatsu-column > .tatsu-column-inner{background-color: rgba(1,36,78,1);border-radius: 10px;}.tatsu-SyoXz-qrdR.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 10% 20% 10% 20%;}.tatsu-SyoXz-qrdR.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-SyoXz-qrdR > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-SyoXz-qrdR > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-SyoXz-qrdR > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-SyoXz-qrdR > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}.tatsu-SyoXz-qrdR.tatsu-column > .tatsu-column-inner > .tatsu-column-bg-image-wrap > .tatsu-column-bg-image{border-radius: 10px;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-SyoXz-qrdR.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-SyoXz-qrdR.tatsu-column{width: 50%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-SyoXz-qrdR.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-animate tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-rJT7MbcB_C" data-animation="fadeInRight" data-parallax-speed="0" style=" padding:0 71px;"><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-rkAmfZ5BO0 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-rkAmfZ5BO0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;}</style> <h4 class="white-text">Versatile In-Chip Assays</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-Syyl7f-5HuA "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-Syyl7f-5HuA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;}</style> <p class="white-text body2">With real-time fluorescent microscopy technology, different assays could be performed in-chip for plasma cell screening, including:</p> <ul class="white-text body2"> <li>Antigen beads binding assay</li> <li>Cell binding assay</li> <li>Competition assay</li> <li>Reporter cell assay</li> </ul> <p class="white-text body2">All these advantages make SBC platform to become highly efficient and robust antibody discovery platform.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-rJT7MbcB_C.tatsu-column{width: 65%;}.tatsu-rJT7MbcB_C.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0px 0% 0px 25%;}.tatsu-rJT7MbcB_C.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-rJT7MbcB_C > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-rJT7MbcB_C > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-rJT7MbcB_C > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-rJT7MbcB_C > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-rJT7MbcB_C.tatsu-column{width: 50%;}.tatsu-rJT7MbcB_C.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0px 5% 0px 0%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-rJT7MbcB_C.tatsu-column{width: 50%;}.tatsu-rJT7MbcB_C.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0px 10% 0px 0px;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-rJT7MbcB_C.tatsu-column{width: 100%;}.tatsu-rJT7MbcB_C.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0px 3% 0px 0px;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-one-half tatsu-row-has-two-cols tatsu-custom-gutter tatsu-reg-cols tatsu-swap-cols tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-tablet tatsu-hide-mobile tatsu-clearfix tatsu-ryeeQf-9Su0" ><style>.tatsu-ryeeQf-9Su0.tatsu-row-wrap > .tatsu-row{padding: 60px 0px 60px 0px;}@media only screen and (max-width: 767px) {.tatsu-ryeeQf-9Su0.tatsu-row-wrap > .tatsu-row{padding: 30px 0px 10px 0px;}}</style><div class="tatsu-row " style="margin-left:-71px;margin-right:-71px;"><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-animate tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-SyZeQMZqrO0" data-animation="fadeInLeft" data-parallax-speed="0" style=" padding:0 71px;"><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-SJfgmf-qr_0 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-SJfgmf-qr_0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;}</style> <h4 class="white-text">Precisely Single Cell Exporting</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-BJXlQG-cBOR "><div class="tatsu-text-inner clearfix" ><style>.tatsu-BJXlQG-cBOR.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-BJXlQG-cBOR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-BJXlQG-cBOR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <p class="white-text body2">Opto-electro positioning (OEP) technology precisely manipulates and unloads cells to 96-well plates preloaded with single-cell sequencing reagents.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-SyZeQMZqrO0.tatsu-column{width: 65%;}.tatsu-SyZeQMZqrO0.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0% 5% 10% 0%;}.tatsu-SyZeQMZqrO0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-SyZeQMZqrO0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-SyZeQMZqrO0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-SyZeQMZqrO0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-SyZeQMZqrO0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-SyZeQMZqrO0.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-SyZeQMZqrO0.tatsu-column{width: 50%;}.tatsu-SyZeQMZqrO0.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0% 1% 10% 3%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-SyZeQMZqrO0.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-animate tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-BJNx7GWqSO0" data-animation="fadeInRight" data-parallax-speed="0" style=" padding:0 71px;"><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-image-lazyload tatsu-external-image tatsu-ryrg7fWqrd0 " ><div class="tatsu-single-image-inner " style="" ><div class = "tatsu-single-image-padding-wrap" style = "" ></div><img class = "tatsu-gradient-border" data-src = "https://nonabio.wpenginepowered.com/wp-content/uploads/2024/01/single-cell-exporting.svg" alt =" " src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-ryrg7fWqrd0 .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-ryrg7fWqrd0.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-BJNx7GWqSO0.tatsu-column{width: 35%;}.tatsu-BJNx7GWqSO0.tatsu-column > .tatsu-column-inner{background-color: rgba(1,36,78,1);border-radius: 10px;}.tatsu-BJNx7GWqSO0.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 10% 20% 10% 20%;}.tatsu-BJNx7GWqSO0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-BJNx7GWqSO0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-BJNx7GWqSO0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-BJNx7GWqSO0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-BJNx7GWqSO0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}.tatsu-BJNx7GWqSO0.tatsu-column > .tatsu-column-inner > .tatsu-column-bg-image-wrap > .tatsu-column-bg-image{border-radius: 10px;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-BJNx7GWqSO0.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-BJNx7GWqSO0.tatsu-column{width: 50%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-BJNx7GWqSO0.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-one-half tatsu-row-has-two-cols tatsu-custom-gutter tatsu-reg-cols tatsu-swap-cols tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-tablet tatsu-hide-mobile tatsu-clearfix tatsu-rJUg7GZqr_A" ><style>.tatsu-rJUg7GZqr_A.tatsu-row-wrap > .tatsu-row{padding: 60px 0px 60px 0px;}@media only screen and (max-width: 767px) {.tatsu-rJUg7GZqr_A.tatsu-row-wrap > .tatsu-row{padding: 30px 0px 10px 0px;}}</style><div class="tatsu-row " style="margin-left:-71px;margin-right:-71px;"><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-animate tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-S1vlQz-9HdC" data-animation="fadeInLeft" data-parallax-speed="0" style=" padding:0 71px;"><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-SkulXG-cHdA "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-SkulXG-cHdA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;}</style> <h4 class="white-text">Precisely Single Cell Exporting</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-ByKxQM-9HuC "><div class="tatsu-text-inner clearfix" ><style>.tatsu-ByKxQM-9HuC.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-ByKxQM-9HuC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-ByKxQM-9HuC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <p class="white-text body2">Opto-electro positioning (OEP) technology precisely manipulates and unloads cells to 96-well plates preloaded with single-cell sequencing reagents.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-S1vlQz-9HdC.tatsu-column{width: 65%;}.tatsu-S1vlQz-9HdC.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0% 5% 10% 0%;}.tatsu-S1vlQz-9HdC.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-S1vlQz-9HdC > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-S1vlQz-9HdC > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-S1vlQz-9HdC > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-S1vlQz-9HdC > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-S1vlQz-9HdC.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-S1vlQz-9HdC.tatsu-column{width: 50%;}.tatsu-S1vlQz-9HdC.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0% 1% 10% 3%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-S1vlQz-9HdC.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-animate tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-rJqxmGWcHd0" data-animation="fadeInRight" data-parallax-speed="0" style=" padding:0 71px;"><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-image-lazyload tatsu-external-image tatsu-SyjgQfWqSuA " ><div class="tatsu-single-image-inner " style="" ><div class = "tatsu-single-image-padding-wrap" style = "" ></div><img class = "tatsu-gradient-border" data-src = "https://nonabio.wpenginepowered.com/wp-content/uploads/2024/01/single-cell-exporting.svg" alt =" " src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-SyjgQfWqSuA .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-SyjgQfWqSuA.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-rJqxmGWcHd0.tatsu-column{width: 35%;}.tatsu-rJqxmGWcHd0.tatsu-column > .tatsu-column-inner{background-color: rgba(1,36,78,1);border-radius: 10px;}.tatsu-rJqxmGWcHd0.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 10% 20% 10% 20%;}.tatsu-rJqxmGWcHd0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-rJqxmGWcHd0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-rJqxmGWcHd0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-rJqxmGWcHd0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-rJqxmGWcHd0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}.tatsu-rJqxmGWcHd0.tatsu-column > .tatsu-column-inner > .tatsu-column-bg-image-wrap > .tatsu-column-bg-image{border-radius: 10px;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-rJqxmGWcHd0.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-rJqxmGWcHd0.tatsu-column{width: 50%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-rJqxmGWcHd0.tatsu-column{width: 100%;}}</style></div></div></div></div><div class="tatsu-section-background-wrap"><div class = "tatsu-section-background" ></div></div><div class="tatsu-overlay tatsu-section-overlay"></div><style>.tatsu-S1XM-cSdA.tatsu-section{background-color: rgba(1,36,78,1);}.tatsu-S1XM-cSdA .tatsu-section-pad{padding: 106px 0px 50px 0px;}.tatsu-S1XM-cSdA .tatsu-section-offset-wrap{transform: translateY(-0px);}.tatsu-S1XM-cSdA > .tatsu-bottom-divider{z-index: 9999;}.tatsu-S1XM-cSdA > .tatsu-top-divider{z-index: 9999;}.tatsu-S1XM-cSdA .tatsu-section-overlay{mix-blend-mode: normal;}@media only screen and (max-width:1377px) {.tatsu-S1XM-cSdA .tatsu-section-pad{padding: 64px 0px 45px 0px;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-S1XM-cSdA .tatsu-section-pad{padding: 46px 0px 50px 0px;}}@media only screen and (max-width: 767px) {.tatsu-S1XM-cSdA .tatsu-section-pad{padding: 35px 0px 20px 0px;}}</style></div><div id="scb-platform" class="tatsu-r1RgJ0e5T tatsu-section tatsu-bg-overlay tatsu-clearfix" data-title="" data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"101px 0px 74px 0px","l":"101px 0px 66px 0px","t":"69px 0px 49px 0px","m":"50px 0px 25px 0px"}' data-padding-top='50px'><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-one-half tatsu-row-has-two-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-S1cTjnLYA" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-Hyx9pi3UYC" data-animation="fadeInUp" data-animation-delay="300" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-HJ-96shUt0 "><div class="tatsu-text-inner clearfix" ><style>.tatsu-HJ-96shUt0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;padding: 0px 0px 11px 0px;color: rgba(1,36,78,1) ;}.tatsu-HJ-96shUt0.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-HJ-96shUt0 .tatsu-text-inner *{color: rgba(1,36,78,1) ;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-HJ-96shUt0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: center;}}@media only screen and (max-width: 767px) {.tatsu-HJ-96shUt0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <h4 style="text-align: left;">Optimized CD3 Activity:</h4> <h4 style="text-align: left;">Balancing Efficacy and Safety</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-S1GcaihIYC "><div class="tatsu-text-inner clearfix" ><style>.tatsu-S1GcaihIYC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(0,21,64,1) ;}.tatsu-S1GcaihIYC.tatsu-text-block-wrap{margin: 21px 0px 30px 0px;}.tatsu-S1GcaihIYC .tatsu-text-inner *{color: rgba(0,21,64,1) ;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-S1GcaihIYC.tatsu-text-block-wrap .tatsu-text-inner{text-align: center;}}@media only screen and (max-width: 767px) {.tatsu-S1GcaihIYC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-S1GcaihIYC.tatsu-text-block-wrap{margin: 10px 0px 30px 0px;}}</style> <p style="text-align: left;">Our CD3 HBICE® variants are designed to adjust binding activity to human T cells, striking a balance between cytotoxicity and cytokine release. This ensures effective tumor targeting while minimizing off-target effects.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-Hyx9pi3UYC.tatsu-column{width: 63.8%;}.tatsu-Hyx9pi3UYC.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-Hyx9pi3UYC > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-Hyx9pi3UYC > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-Hyx9pi3UYC > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-Hyx9pi3UYC > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-Hyx9pi3UYC.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-Hyx9pi3UYC.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-Hyx9pi3UYC.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-column-image-none tatsu-column-effect-none tatsu-Sy7qas2UKR" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-rJ49Tsh8FA " data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 1313px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 74.7905559787%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "CD3 HBICE" data-src = "https://nonabio.com/wp-content/uploads/2024/07/CD3-HBICE.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-rJ49Tsh8FA .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-rJ49Tsh8FA.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (max-width:1377px) {.tatsu-rJ49Tsh8FA .tatsu-single-image-inner{max-width: 69%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-rJ49Tsh8FA .tatsu-single-image-inner{max-width: 52%;}}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-Sy7qas2UKR.tatsu-column{width: 36.2%;}.tatsu-Sy7qas2UKR.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-Sy7qas2UKR > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-Sy7qas2UKR > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-Sy7qas2UKR > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-Sy7qas2UKR > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-Sy7qas2UKR.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-Sy7qas2UKR.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-Sy7qas2UKR.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-HJQ0D2UtR" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-SklmCD2IYA" data-animation="fadeInUp" data-animation-delay="300" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-image-lazyload tatsu-rJ7QAw2IY0 tatsu-hide-mobile" ><div class="tatsu-single-image-inner " style="width : 1199px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 46.3719766472%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "Optimized CD3 Activity" data-src = "https://nonabio.com/wp-content/uploads/2024/08/Optimized-CD3-Activity-1.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-rJ7QAw2IY0{margin: 0px 0px 34px 0px;}.tatsu-rJ7QAw2IY0 .tatsu-single-image-inner{border-style: none;border-width: 1px;border-color: #03A9F4; max-width: 81%;border-radius: 10px;}.tatsu-rJ7QAw2IY0.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-rJ7QAw2IY0 .tatsu-single-image-inner{max-width: 95%;}}@media only screen and (max-width: 767px) {.tatsu-rJ7QAw2IY0 .tatsu-single-image-inner{max-width: 100%;}}</style></div><div class="tatsu-single-image tatsu-module align-center tatsu-image-lazyload tatsu-BkG1pelcR tatsu-hide-tablet tatsu-hide-laptop tatsu-hide-desktop" ><div class="tatsu-single-image-inner " style="width : 479px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 197.494780793%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "1" data-src = "https://nonabio.com/wp-content/uploads/2024/08/1-2.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-BkG1pelcR{margin: 0px 0px 34px 0px;}.tatsu-BkG1pelcR .tatsu-single-image-inner{border-style: none;border-width: 1px;border-color: #03A9F4; max-width: 81%;border-radius: 10px;}.tatsu-BkG1pelcR.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-BkG1pelcR .tatsu-single-image-inner{max-width: 95%;}}@media only screen and (max-width: 767px) {.tatsu-BkG1pelcR .tatsu-single-image-inner{max-width: 100%;}}</style></div><div class="tatsu-single-image tatsu-module align-center tatsu-image-lazyload tatsu-BkL-aeg5C tatsu-hide-tablet tatsu-hide-laptop tatsu-hide-desktop" ><div class="tatsu-single-image-inner " style="width : 526px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 179.847908745%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "2" data-src = "https://nonabio.com/wp-content/uploads/2024/08/2-2.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-BkL-aeg5C{margin: 0px 0px 34px 0px;}.tatsu-BkL-aeg5C .tatsu-single-image-inner{border-style: none;border-width: 1px;border-color: #03A9F4; max-width: 81%;border-radius: 10px;}.tatsu-BkL-aeg5C.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-BkL-aeg5C .tatsu-single-image-inner{max-width: 95%;}}@media only screen and (max-width: 767px) {.tatsu-BkL-aeg5C .tatsu-single-image-inner{max-width: 100%;}}</style></div><div class="tatsu-module tatsu-text-block-wrap tatsu-By3UunItA "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-By3UunItA.tatsu-text-block-wrap .tatsu-text-inner{width: 71%;text-align: left;color: rgba(28,87,116,1) ;}.tatsu-By3UunItA.tatsu-text-block-wrap{margin: 0px 0px 29px 0px;}.tatsu-By3UunItA .tatsu-text-inner *{color: rgba(28,87,116,1) ;}@media only screen and (max-width: 767px) {.tatsu-By3UunItA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-By3UunItA.tatsu-text-block-wrap{margin: 10px 0px 30px 0px;}}</style> <p style="text-align: left;"><strong>Functional Assessment of BCMA x CD3 suggests a balanced profile of efficacy and safety. </strong></p> <p style="text-align: left;">BCMA x CD3 depletes BCMA-positive cells with limited cytokine release. No off-target killing on BCMA-negative HL-60 cells (A). No T cell activation for CD4+ or CD8+ cells (B). Strong cytotoxicity to BCMA-high NCI-H929 cells (C). Lower cytokine release (IL6, TNF-α) compared to control TAB3 (D).</p> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-rkFVu2UYR "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-rkFVu2UYR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;padding: 0px 0px 11px 0px;color: rgba(1,36,78,1) ;}.tatsu-rkFVu2UYR.tatsu-text-block-wrap{margin: 67px 0px 0px 0px;}.tatsu-rkFVu2UYR .tatsu-text-inner *{color: rgba(1,36,78,1) ;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-rkFVu2UYR.tatsu-text-block-wrap .tatsu-text-inner{width: 75%;}}@media only screen and (max-width: 767px) {.tatsu-rkFVu2UYR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <h4 style="text-align: center;">Versatile Formats for Diverse Therapeutic Needs</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-S1L_hkec0 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-S1L_hkec0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(0,21,64,1) ;}.tatsu-S1L_hkec0.tatsu-text-block-wrap{margin: 21px 0px 30px 0px;}.tatsu-S1L_hkec0 .tatsu-text-inner *{color: rgba(0,21,64,1) ;}@media only screen and (max-width: 767px) {.tatsu-S1L_hkec0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-S1L_hkec0.tatsu-text-block-wrap{margin: 10px 0px 30px 0px;}}</style> <p style="text-align: left;">CD3 HCAbs offer diverse and flexible formats to fit various therapeutic geometries, providing a robust platform for creating effective TAA×CD3 engagers (‘2+1’ HBICE®). Our technologies ensure the potent killing of TAA-positive tumor cells while maintaining safety and specificity.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-SklmCD2IYA.tatsu-column{width: 100%;}.tatsu-SklmCD2IYA.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-SklmCD2IYA > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-SklmCD2IYA > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-SklmCD2IYA > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-SklmCD2IYA > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-SklmCD2IYA.tatsu-column{width: 99%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-SklmCD2IYA.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-SklmCD2IYA.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-three-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-H1ldFWxn_R" ><style>.tatsu-H1ldFWxn_R.tatsu-row-wrap > .tatsu-row{padding: 2px 3px 30px 0px;}@media only screen and (max-width: 767px) {.tatsu-H1ldFWxn_R.tatsu-row-wrap > .tatsu-row{padding: 0px 0px 6px 0px;}}</style><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-third tatsu-column-image-none tatsu-column-effect-none tatsu-rydDMxn_C" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module tatsu-image-lazyload tatsu-HJ3YWl2dC " ><div class="tatsu-single-image-inner " style="width : 550px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 81.6363636364%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "TAA1" data-src = "https://nonabio.com/wp-content/uploads/2024/07/TAA1.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-HJ3YWl2dC .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-HJ3YWl2dC.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-rydDMxn_C.tatsu-column{width: 33.33%;}.tatsu-rydDMxn_C.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-rydDMxn_C > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-rydDMxn_C > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-rydDMxn_C > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-rydDMxn_C > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-rydDMxn_C.tatsu-column{width: 33.33%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-rydDMxn_C.tatsu-column{width: 33%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-rydDMxn_C.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-third tatsu-column-image-none tatsu-column-effect-none tatsu-BylODfe3_A" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module tatsu-image-lazyload tatsu-rkhvfl3_A " ><div class="tatsu-single-image-inner " style="width : 530px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 80.3773584906%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "TAA2" data-src = "https://nonabio.com/wp-content/uploads/2024/07/TAA2.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-rkhvfl3_A .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-rkhvfl3_A.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-BylODfe3_A.tatsu-column{width: 33.33%;}.tatsu-BylODfe3_A.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-BylODfe3_A > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-BylODfe3_A > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-BylODfe3_A > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-BylODfe3_A > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-BylODfe3_A.tatsu-column{width: 33.33%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-BylODfe3_A.tatsu-column{width: 33%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-BylODfe3_A.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-third tatsu-column-image-none tatsu-column-effect-none tatsu-ryWgG8vTu0" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module tatsu-image-lazyload tatsu-H18tzehu0 " ><div class="tatsu-single-image-inner " style="width : 523px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 80.6883365201%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "TAA3" data-src = "https://nonabio.com/wp-content/uploads/2024/07/TAA3.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-H18tzehu0 .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-H18tzehu0.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-ryWgG8vTu0.tatsu-column{width: 33.33%;}.tatsu-ryWgG8vTu0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-ryWgG8vTu0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-ryWgG8vTu0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-ryWgG8vTu0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-ryWgG8vTu0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-ryWgG8vTu0.tatsu-column{width: 33.33%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-ryWgG8vTu0.tatsu-column{width: 33%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-ryWgG8vTu0.tatsu-column{width: 100%;}}</style></div></div></div></div><div class="tatsu-section-background-wrap"><div class = "tatsu-section-background" ></div></div><div class="tatsu-overlay tatsu-section-overlay"></div><style>.tatsu-r1RgJ0e5T.tatsu-section{background-color: rgba(221,241,255,1);}.tatsu-r1RgJ0e5T .tatsu-section-pad{padding: 101px 0px 74px 0px;}.tatsu-r1RgJ0e5T .tatsu-section-offset-wrap{transform: translateY(-0px);}.tatsu-r1RgJ0e5T > .tatsu-bottom-divider{z-index: 9999;}.tatsu-r1RgJ0e5T > .tatsu-top-divider{z-index: 9999;}.tatsu-r1RgJ0e5T .tatsu-section-overlay{mix-blend-mode: normal;}@media only screen and (max-width:1377px) {.tatsu-r1RgJ0e5T .tatsu-section-pad{padding: 101px 0px 66px 0px;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-r1RgJ0e5T .tatsu-section-pad{padding: 69px 0px 49px 0px;}}@media only screen and (max-width: 767px) {.tatsu-r1RgJ0e5T .tatsu-section-pad{padding: 50px 0px 25px 0px;}}</style></div><div id="HBICE MOA 2" class="tatsu-ryMcqZJF0 tatsu-section tatsu-bg-overlay tatsu-clearfix" data-title="Section 6" data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"134px 0px 101px 0px","l":"67px 0px 50px 0px","t":"64px 0px 50px 0px","m":"33px 0px 42px 0px"}' data-padding-top='33px'><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-rylM95ZJFA" ><style>.tatsu-rylM95ZJFA > .tatsu-row{margin-top: 0px;}.tatsu-rylM95ZJFA.tatsu-row-wrap > .tatsu-row{margin-bottom: 30px;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-rylM95ZJFA > .tatsu-row{margin-top: 0px;}.tatsu-rylM95ZJFA.tatsu-row-wrap > .tatsu-row{margin-bottom: 0px;}}@media only screen and (max-width: 767px) {.tatsu-rylM95ZJFA > .tatsu-row{margin-top: 0px;}.tatsu-rylM95ZJFA.tatsu-row-wrap > .tatsu-row{margin-bottom: 1px;}}</style><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-BJWfccWyK0" data-animation="fadeInLeft" data-animation-delay="300" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-HkzMccZ1KA tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-tablet tatsu-hide-mobile "><div class="tatsu-text-inner tatsu-align-right clearfix" ><style>.tatsu-HkzMccZ1KA.tatsu-text-block-wrap .tatsu-text-inner{width: 75%;text-align: left;color: #ffffff ;}.tatsu-HkzMccZ1KA.tatsu-text-block-wrap{margin: 40px 0px 30px 0px;}.tatsu-HkzMccZ1KA .tatsu-text-inner *{color: #ffffff ;}@media only screen and (max-width:1377px) {.tatsu-HkzMccZ1KA.tatsu-text-block-wrap{margin: 20px 0px 10px 0px;}}@media only screen and (max-width: 767px) {.tatsu-HkzMccZ1KA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <h4 style="text-align: left;">Introduction</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-rkz86qACdR "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-rkz86qACdR.tatsu-text-block-wrap .tatsu-text-inner{width: 91%;text-align: center;color: rgba(241,142,37,1) ;}.tatsu-rkz86qACdR.tatsu-text-block-wrap{margin: 0px 0px 22px 0px;}.tatsu-rkz86qACdR .tatsu-text-inner *{color: rgba(241,142,37,1) ;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-rkz86qACdR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-rkz86qACdR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-rkz86qACdR.tatsu-text-block-wrap{margin: 0px 0px 10px 0px;}}</style> <h5 class="white-text" style="text-align: center;">HBICE MOA 2</h5> <h5 class="white-text" style="text-align: center;">(TAA targeting for costimulatory signal)</h5> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HkrUS-yFC "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-HkrUS-yFC.tatsu-text-block-wrap .tatsu-text-inner{width: 91%;text-align: center;}.tatsu-HkrUS-yFC.tatsu-text-block-wrap{margin: 0px 0px 23px 0px;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-HkrUS-yFC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-HkrUS-yFC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-HkrUS-yFC.tatsu-text-block-wrap{margin: 8px 0px 19px 0px;}}</style> <h4 class="white-text" style="text-align: center;">Tumor-Specific T Cell Activation by TAA Engagement</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HkBUa5RAO0 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-HkBUa5RAO0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(255,255,255,1) ;}.tatsu-HkBUa5RAO0 .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (max-width:1377px) {.tatsu-HkBUa5RAO0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-HkBUa5RAO0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-HkBUa5RAO0.tatsu-text-block-wrap{margin: 0px 0px 32px 0px;}}</style> <p>Leveraging our proprietary HBICE® platform, we can enhance the immune response by activating T cells within tumor microenvironment (TME), focusing on targeting tumor-associated antigens (TAAs) to deliver a potent and precise attack against cancer cells.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-BJWfccWyK0.tatsu-column{width: 100%;}.tatsu-BJWfccWyK0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-BJWfccWyK0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-BJWfccWyK0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-BJWfccWyK0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-BJWfccWyK0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-BJWfccWyK0.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-BJWfccWyK0.tatsu-column{width: 97.3%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-BJWfccWyK0.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-one-half tatsu-row-has-two-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-rko6a3LtA" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-BkliTp3UFA" data-animation="fadeInUp" data-animation-delay="300" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-rJrTBxdYC "><div class="tatsu-text-inner clearfix" ><style>.tatsu-rJrTBxdYC.tatsu-text-block-wrap .tatsu-text-inner{width: 62%;text-align: center;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 15px 15px 15px 15px;color: rgba(255,255,255,1) ;}.tatsu-rJrTBxdYC.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-rJrTBxdYC .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (max-width:1377px) {.tatsu-rJrTBxdYC.tatsu-text-block-wrap .tatsu-text-inner{width: 95%;text-align: center;}}@media only screen and (max-width: 767px) {.tatsu-rJrTBxdYC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <h5><strong>HBICE®: A Dual Signal Approach</strong></h5> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HJfsaT38Y0 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-HJfsaT38Y0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: #ffffff ;}.tatsu-HJfsaT38Y0.tatsu-text-block-wrap{margin: 21px 0px 30px 0px;}.tatsu-HJfsaT38Y0 .tatsu-text-inner *{color: #ffffff ;}@media only screen and (max-width: 767px) {.tatsu-HJfsaT38Y0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-HJfsaT38Y0.tatsu-text-block-wrap{margin: 16px 0px 30px 0px;}}</style> <p>Our HBICE® platform is designed to provide robust T cell activation through a dual signal mechanism. This involves the engagement of both the primary TCR (T-cell receptor) signal and the co-stimulatory signal, essential for effective T cell activation, proliferation, and memory formation.</p> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-SJU4EGdYC "><div class="tatsu-text-inner clearfix" ><style>.tatsu-SJU4EGdYC.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;color: rgba(238,119,31,1) ;}.tatsu-SJU4EGdYC.tatsu-text-block-wrap{margin: 0px 0px 13px 0px;}.tatsu-SJU4EGdYC .tatsu-text-inner *{color: rgba(238,119,31,1) ;}@media only screen and (max-width:1377px) {.tatsu-SJU4EGdYC.tatsu-text-block-wrap{margin: 0px 0px 10px 0px;}}@media only screen and (max-width: 767px) {.tatsu-SJU4EGdYC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <h5><strong>1. Primary TCR Signal</strong>:</h5> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-By69EfdFA "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-By69EfdFA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: #ffffff ;}.tatsu-By69EfdFA.tatsu-text-block-wrap{margin: 5px 0px 30px 0px;}.tatsu-By69EfdFA .tatsu-text-inner *{color: #ffffff ;}@media only screen and (max-width: 767px) {.tatsu-By69EfdFA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-By69EfdFA.tatsu-text-block-wrap{margin: 10px 0px 30px 0px;}}</style> <p>The HBICE® engages the TCR-CD3 complex on T cells, initiating the primary signal essential for T cell activation.</p> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-SJO5VfdtA "><div class="tatsu-text-inner clearfix" ><style>.tatsu-SJO5VfdtA.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: left;color: rgba(238,119,31,1) ;}.tatsu-SJO5VfdtA.tatsu-text-block-wrap{margin: 0px 0px 12px 0px;}.tatsu-SJO5VfdtA .tatsu-text-inner *{color: rgba(238,119,31,1) ;}@media only screen and (max-width:1377px) {.tatsu-SJO5VfdtA.tatsu-text-block-wrap{margin: 0px 0px 10px 0px;}}@media only screen and (max-width: 767px) {.tatsu-SJO5VfdtA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <h5><strong>2. Co-Stimulatory Signal</strong>:</h5> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HJrvEzdKR "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-HJrvEzdKR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: #ffffff ;}.tatsu-HJrvEzdKR.tatsu-text-block-wrap{margin: 5px 0px 30px 0px;}.tatsu-HJrvEzdKR .tatsu-text-inner *{color: #ffffff ;}@media only screen and (max-width: 767px) {.tatsu-HJrvEzdKR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}.tatsu-HJrvEzdKR.tatsu-text-block-wrap{margin: 10px 0px 30px 0px;}}</style> <p>The HBICE® simultaneously delivers a co-stimulatory signal, enhancing T cell activation and promoting a sustained immune response. This dual engagement is crucial for effective anti-tumor immunity.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-BkliTp3UFA.tatsu-column{width: 59.7%;}.tatsu-BkliTp3UFA.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-BkliTp3UFA > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-BkliTp3UFA > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-BkliTp3UFA > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-BkliTp3UFA > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-BkliTp3UFA.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-BkliTp3UFA.tatsu-column{width: 95.8%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-BkliTp3UFA.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-column-image-none tatsu-column-effect-none tatsu-S1ms6ThUFC" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-S1Vja63LY0 " data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 1409px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 92.9737402413%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "T-cell engagers 2" data-src = "https://nonabio.com/wp-content/uploads/2024/07/T-cell-engagers-2.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-S1Vja63LY0 .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-S1Vja63LY0.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (max-width:1377px) {.tatsu-S1Vja63LY0 .tatsu-single-image-inner{max-width: 87%;}.tatsu-S1Vja63LY0{padding: 18px 0px 0px 0px;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-S1Vja63LY0 .tatsu-single-image-inner{max-width: 51%;}}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-S1ms6ThUFC.tatsu-column{width: 40.3%;}.tatsu-S1ms6ThUFC.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-S1ms6ThUFC > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-S1ms6ThUFC > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-S1ms6ThUFC > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-S1ms6ThUFC > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-S1ms6ThUFC.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-S1ms6ThUFC.tatsu-column{width: 99.8%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-S1ms6ThUFC.tatsu-column{width: 100%;}}</style></div></div></div></div><div class="tatsu-section-background-wrap"><div class = "tatsu-section-background" ></div></div><div class="tatsu-overlay tatsu-section-overlay"></div><style>.tatsu-ryMcqZJF0.tatsu-section{background-color: rgba(1,36,78,1);}.tatsu-ryMcqZJF0 .tatsu-section-background{background-image: url(https://nonabio.wpenginepowered.com/wp-content/uploads/2024/01/beacon-antibody-discovery-v2.svg);background-repeat: no-repeat;background-attachment: scroll;background-position: center center;background-size: cover;}.tatsu-ryMcqZJF0 .tatsu-bg-blur{background-repeat: no-repeat;background-attachment: scroll;background-position: center center;background-size: cover;}.tatsu-ryMcqZJF0 .tatsu-section-pad{padding: 134px 0px 101px 0px;}.tatsu-ryMcqZJF0 .tatsu-section-offset-wrap{transform: translateY(-0px);}.tatsu-ryMcqZJF0 > .tatsu-bottom-divider{z-index: 9999;}.tatsu-ryMcqZJF0 > .tatsu-top-divider{z-index: 9999;}.tatsu-ryMcqZJF0 .tatsu-section-overlay{mix-blend-mode: normal;}@media only screen and (max-width:1377px) {.tatsu-ryMcqZJF0 .tatsu-section-pad{padding: 67px 0px 50px 0px;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-ryMcqZJF0 .tatsu-section-pad{padding: 64px 0px 50px 0px;}}@media only screen and (max-width: 767px) {.tatsu-ryMcqZJF0 .tatsu-section-pad{padding: 33px 0px 42px 0px;}}</style></div><div id="scb-platform" class="tatsu-r1JEsCAdA tatsu-section tatsu-bg-overlay tatsu-clearfix" data-title="Section 7" data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"72px 0px 54px 0px","m":"34px 0px 15px 0px","t":"59px 0px 20px 0px"}' data-padding-top='34px'><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-SklyNjRR_R" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-HJZkVs0CdC" data-animation="fadeInUp" data-animation-delay="300" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-HJaYCOoqR "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-HJaYCOoqR.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: center;color: rgba(1,36,78,1) ;}.tatsu-HJaYCOoqR.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-HJaYCOoqR .tatsu-text-inner *{color: rgba(1,36,78,1) ;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-HJaYCOoqR.tatsu-text-block-wrap .tatsu-text-inner{width: 75%;}}@media only screen and (max-width: 767px) {.tatsu-HJaYCOoqR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <h4>4-1BB HBICE®: Tumor-Specific Activation</h4> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-rkvbyaIFR "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-rkvbyaIFR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(0,21,64,1) ;}.tatsu-rkvbyaIFR.tatsu-text-block-wrap{margin: 21px 0px 30px 0px;}.tatsu-rkvbyaIFR .tatsu-text-inner *{color: rgba(0,21,64,1) ;}@media only screen and (max-width: 767px) {.tatsu-rkvbyaIFR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;padding: 0px 3px 0px 0px;}.tatsu-rkvbyaIFR.tatsu-text-block-wrap{margin: 9px 5px 0px 0px;}}</style> <p>Our 4-1BB HBICE® selectively activates T cells in the presence of TAAs, ensuring targeted and controlled immune responses. Key benefits include:</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-HJZkVs0CdC.tatsu-column{width: 100%;}.tatsu-HJZkVs0CdC.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-HJZkVs0CdC > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-HJZkVs0CdC > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-HJZkVs0CdC > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-HJZkVs0CdC > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-HJZkVs0CdC.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-HJZkVs0CdC.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-HJZkVs0CdC.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-Syyg1VsRCdR" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-column-image-none tatsu-column-effect-none tatsu-rJleyNsR0OR" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-B1SWOMuKR "><div class="tatsu-text-inner clearfix" ><style>.tatsu-B1SWOMuKR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 40px 40px 40px 40px;color: rgba(255,255,255,1) ;}.tatsu-B1SWOMuKR.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-B1SWOMuKR .tatsu-text-inner *{color: rgba(255,255,255,1) ;}</style> <h5><strong>Selective Activation</strong>:</h5> <p>Activates T cells only with TAAs, minimizing off-target effects and reducing toxicity.</p> </div></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-BkmxyNo0Cu0 " data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 1296px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 25.5401234568%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "Selective Activation" data-src = "https://nonabio.com/wp-content/uploads/2024/07/Selective-Activation.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-BkmxyNo0Cu0{margin: 16px 0px 0px 0px;}.tatsu-BkmxyNo0Cu0 .tatsu-single-image-inner{border-style: solid;max-width: 92%;}.tatsu-BkmxyNo0Cu0.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-ry0W1be9A tatsu-hide-tablet tatsu-hide-laptop tatsu-hide-desktop" data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 423px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 210.874704492%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "Group 1000001975" data-src = "https://nonabio.com/wp-content/uploads/2024/08/Group-1000001975.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-ry0W1be9A{margin: 16px 0px 0px 0px;}.tatsu-ry0W1be9A .tatsu-single-image-inner{border-style: solid;max-width: 92%;}.tatsu-ry0W1be9A.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-rJleyNsR0OR.tatsu-column{width: 100%;}.tatsu-rJleyNsR0OR.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-rJleyNsR0OR > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-rJleyNsR0OR > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-rJleyNsR0OR > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-rJleyNsR0OR > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-rJleyNsR0OR.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-rJleyNsR0OR.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-rJleyNsR0OR.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-ry3x14oAAO0" ><style>.tatsu-ry3x14oAAO0 > .tatsu-row{margin-top: 20px;}.tatsu-ry3x14oAAO0.tatsu-row-wrap > .tatsu-row{margin-bottom: 0px;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-ry3x14oAAO0 > .tatsu-row{margin-top: 17px;}.tatsu-ry3x14oAAO0.tatsu-row-wrap > .tatsu-row{margin-bottom: 0px;}}@media only screen and (max-width: 767px) {.tatsu-ry3x14oAAO0 > .tatsu-row{margin-top: 14px;}.tatsu-ry3x14oAAO0.tatsu-row-wrap > .tatsu-row{margin-bottom: 0px;}}</style><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-column-image-none tatsu-column-effect-none tatsu-SJ6xkNoCRO0" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-ryRe1Ei0R_0 "><div class="tatsu-text-inner clearfix" ><style>.tatsu-ryRe1Ei0R_0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 40px 40px 40px 40px;color: rgba(255,255,255,1) ;}.tatsu-ryRe1Ei0R_0.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-ryRe1Ei0R_0 .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (max-width: 767px) {.tatsu-ryRe1Ei0R_0.tatsu-text-block-wrap .tatsu-text-inner{padding: 20px 20px 20px 20px;}}</style> <h5><strong>Enhanced Efficacy</strong>:</h5> <p>Combines with CD3 HBICE® to provide both TCR and co-stimulatory signals, boosting T cell proliferation and sustained cytotoxicity against tumors.</p> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-ryk-kVi00O0 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-ryk-kVi00O0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(1,36,78,1) ;}.tatsu-ryk-kVi00O0.tatsu-text-block-wrap{margin: 0px 0px 15px 0px;}.tatsu-ryk-kVi00O0 .tatsu-text-inner *{color: rgba(1,36,78,1) ;}</style></div></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-ry--kVj00d0 tatsu-hide-mobile tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-tablet" data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 1147px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 37.1403661726%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "Enhanced Efficacy" data-src = "https://nonabio.com/wp-content/uploads/2024/08/Enhanced-Efficacy.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-ry--kVj00d0 .tatsu-single-image-inner{border-style: solid;max-width: 78%;}.tatsu-ry--kVj00d0.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-ry--kVj00d0 .tatsu-single-image-inner{max-width: 100%;}}</style></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-rJbJebl90 tatsu-hide-tablet tatsu-hide-laptop tatsu-hide-desktop tatsu-hide-mobile" data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 642px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 132.710280374%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "Group 1000001976" data-src = "https://nonabio.com/wp-content/uploads/2024/08/Group-1000001976-1.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-rJbJebl90 .tatsu-single-image-inner{border-style: solid;max-width: 78%;}.tatsu-rJbJebl90.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (max-width: 767px) {.tatsu-rJbJebl90 .tatsu-single-image-inner{max-width: 100%;}}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-SJ6xkNoCRO0.tatsu-column{width: 100%;}.tatsu-SJ6xkNoCRO0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-SJ6xkNoCRO0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-SJ6xkNoCRO0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-SJ6xkNoCRO0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-SJ6xkNoCRO0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-SJ6xkNoCRO0.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-SJ6xkNoCRO0.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-SJ6xkNoCRO0.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-HyPZk4iRROA" ><style>.tatsu-HyPZk4iRROA > .tatsu-row{margin-top: 20px;}.tatsu-HyPZk4iRROA.tatsu-row-wrap > .tatsu-row{margin-bottom: 0px;}</style><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-column-image-none tatsu-column-effect-none tatsu-r1uZkNjAR_A" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-SyYbJEoAAdA "><div class="tatsu-text-inner clearfix" ><style>.tatsu-SyYbJEoAAdA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 40px 40px 40px 40px;color: rgba(255,255,255,1) ;}.tatsu-SyYbJEoAAdA.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-SyYbJEoAAdA .tatsu-text-inner *{color: rgba(255,255,255,1) ;}</style> <h5><strong>Plug & Play system</strong>:</h5> <p>4-1BB HCAb-based HBICE can rapidly generate tumor-specific bispecific antibodies from existing anti-TAA H2L2 sequences.</p> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-S19by4sCRdR "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-S19by4sCRdR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(1,36,78,1) ;}.tatsu-S19by4sCRdR.tatsu-text-block-wrap{margin: 0px 0px 15px 0px;}.tatsu-S19by4sCRdR .tatsu-text-inner *{color: rgba(1,36,78,1) ;}</style></div></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-B12WyVjC0OR tatsu-hide-mobile tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-tablet" data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 4079px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 45.8445697475%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "Plug & Play system" data-src = "https://nonabio.com/wp-content/uploads/2024/08/Plug-Play-system.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-B12WyVjC0OR .tatsu-single-image-inner{border-style: solid;max-width: 90%;}.tatsu-B12WyVjC0OR.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-SyrXlWl5A tatsu-hide-tablet tatsu-hide-laptop tatsu-hide-desktop tatsu-hide-mobile" data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 1314px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 209.284627093%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "Picture7" data-src = "https://nonabio.com/wp-content/uploads/2024/08/Picture7.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-SyrXlWl5A .tatsu-single-image-inner{border-style: solid;max-width: 90%;}.tatsu-SyrXlWl5A.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-B1oWfWe9C tatsu-hide-tablet tatsu-hide-laptop tatsu-hide-desktop tatsu-hide-mobile" data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 1948px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 98.1519507187%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "Group 1000001977" data-src = "https://nonabio.com/wp-content/uploads/2024/08/Group-1000001977-1.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-B1oWfWe9C .tatsu-single-image-inner{border-style: solid;max-width: 90%;}.tatsu-B1oWfWe9C.tatsu-single-image{transform: translate3d(0px,0px, 0);}@media only screen and (max-width: 767px) {.tatsu-B1oWfWe9C .tatsu-single-image-inner{max-width: 100%;}}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-r1uZkNjAR_A.tatsu-column{width: 100%;}.tatsu-r1uZkNjAR_A.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-r1uZkNjAR_A > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-r1uZkNjAR_A > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-r1uZkNjAR_A > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-r1uZkNjAR_A > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-r1uZkNjAR_A.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-r1uZkNjAR_A.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-r1uZkNjAR_A.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-H11jIZ1FC" ><style>.tatsu-H11jIZ1FC > .tatsu-row{margin-top: 20px;}.tatsu-H11jIZ1FC.tatsu-row-wrap > .tatsu-row{margin-bottom: 0px;}</style><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-column-image-none tatsu-column-effect-none tatsu-r1lysL-kYC" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-rkWJoI-yKR "><div class="tatsu-text-inner clearfix" ><style>.tatsu-rkWJoI-yKR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 40px 40px 40px 40px;color: rgba(255,255,255,1) ;}.tatsu-rkWJoI-yKR.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-rkWJoI-yKR .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (max-width: 767px) {.tatsu-rkWJoI-yKR.tatsu-text-block-wrap .tatsu-text-inner{padding: 25px 25px 25px 25px;}}</style> <h5><strong>Broad Applicability</strong>:</h5> <p>Extends to other immune cells (NK, macrophages, dendritic), enabling a comprehensive cancer immunotherapy approach.</p> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HkGks8WJYA "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-HkGks8WJYA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(1,36,78,1) ;}.tatsu-HkGks8WJYA.tatsu-text-block-wrap{margin: 0px 0px 15px 0px;}.tatsu-HkGks8WJYA .tatsu-text-inner *{color: rgba(1,36,78,1) ;}</style></div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-r1lysL-kYC.tatsu-column{width: 100%;}.tatsu-r1lysL-kYC.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-r1lysL-kYC > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-r1lysL-kYC > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-r1lysL-kYC > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-r1lysL-kYC > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-r1lysL-kYC.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-r1lysL-kYC.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-r1lysL-kYC.tatsu-column{width: 100%;}}</style></div></div></div></div><div class="tatsu-section-background-wrap"><div class = "tatsu-section-background" ></div></div><div class="tatsu-overlay tatsu-section-overlay"></div><style>.tatsu-r1JEsCAdA.tatsu-section{background-color: rgba(221,241,255,1);}.tatsu-r1JEsCAdA .tatsu-section-pad{padding: 72px 0px 54px 0px;}.tatsu-r1JEsCAdA .tatsu-section-offset-wrap{transform: translateY(-0px);}.tatsu-r1JEsCAdA > .tatsu-bottom-divider{z-index: 9999;}.tatsu-r1JEsCAdA > .tatsu-top-divider{z-index: 9999;}.tatsu-r1JEsCAdA .tatsu-section-overlay{mix-blend-mode: normal;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-r1JEsCAdA .tatsu-section-pad{padding: 59px 0px 20px 0px;}}@media only screen and (max-width: 767px) {.tatsu-r1JEsCAdA .tatsu-section-pad{padding: 34px 0px 15px 0px;}}</style></div><div id="scb-platform" class="tatsu-H1QeKMdtR tatsu-section tatsu-bg-overlay tatsu-clearfix" data-title="Section 7" data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"54px 0px 62px 0px","m":"17px 0px 25px 0px","t":"44px 0px 40px 0px"}' data-padding-top='17px'><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-B1lQxFf_t0" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-HJ-XetGOYA" data-animation="fadeInUp" data-animation-delay="300" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-SkGk4j0ROR "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-SkGk4j0ROR.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: center;color: rgba(1,36,78,1) ;}.tatsu-SkGk4j0ROR.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-SkGk4j0ROR .tatsu-text-inner *{color: rgba(1,36,78,1) ;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-SkGk4j0ROR.tatsu-text-block-wrap .tatsu-text-inner{width: 75%;}}@media only screen and (max-width: 767px) {.tatsu-SkGk4j0ROR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <h4>4-1BB HBICE®: Tumor-Specific Activation</h4> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-HJ-XetGOYA.tatsu-column{width: 100%;}.tatsu-HJ-XetGOYA.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-HJ-XetGOYA > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-HJ-XetGOYA > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-HJ-XetGOYA > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-HJ-XetGOYA > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-HJ-XetGOYA.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-HJ-XetGOYA.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-HJ-XetGOYA.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-HkNXxtM_KC" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-column-image-none tatsu-column-effect-none tatsu-Syr7gtfuK0" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-HkbFSrdtA "><div class="tatsu-text-inner clearfix" ><style>.tatsu-HkbFSrdtA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;border-radius: 10px;padding: 10px 10px 10px 10px;color: rgba(1,36,78,1) ;}.tatsu-HkbFSrdtA.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-HkbFSrdtA .tatsu-text-inner *{color: rgba(1,36,78,1) ;}</style> <h5><strong>Anti-Tumor Efficacy and Prolonged Survival</strong></h5> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-H184HSdK0 "><div class="tatsu-text-inner clearfix" ><style>.tatsu-H184HSdK0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;border-radius: 10px;padding: 20px 20px 20px 20px;color: rgba(1,36,78,1) ;}.tatsu-H184HSdK0.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-H184HSdK0 .tatsu-text-inner *{color: rgba(1,36,78,1) ;}</style> <p><em>In vivo</em> studies show that our B7H4×4-1BB HBICE® significantly inhibited tumor growth and improved survival in syngeneic mouse models.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-Syr7gtfuK0.tatsu-column{width: 100%;}.tatsu-Syr7gtfuK0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-Syr7gtfuK0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-Syr7gtfuK0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-Syr7gtfuK0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-Syr7gtfuK0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-Syr7gtfuK0.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-Syr7gtfuK0.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-Syr7gtfuK0.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-one-half tatsu-row-has-two-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-S1Jqq7utC" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-column-image-none tatsu-column-effect-none tatsu-Bylyqc7OtC" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-H1CXlYzOF0 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-H1CXlYzOF0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: center;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 9px 9px 9px 9px;color: rgba(255,255,255,1) ;}.tatsu-H1CXlYzOF0.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-H1CXlYzOF0 .tatsu-text-inner *{color: rgba(255,255,255,1) ;}</style> <h6>Inhibits tumor growth in the h4-1BB<br />KI/CT26-B7H4 syngeneic mouse model</h6> </div></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-S1vXgtfOFR " data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 629px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 81.0810810811%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "BALB1" data-src = "https://nonabio.com/wp-content/uploads/2024/08/BALB1-1.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-S1vXgtfOFR{margin: 16px 0px 0px 0px;}.tatsu-S1vXgtfOFR .tatsu-single-image-inner{border-style: solid;max-width: 85%;}.tatsu-S1vXgtfOFR.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-Bylyqc7OtC.tatsu-column{width: 49.2%;}.tatsu-Bylyqc7OtC.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-Bylyqc7OtC > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-Bylyqc7OtC > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-Bylyqc7OtC > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-Bylyqc7OtC > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-Bylyqc7OtC.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-Bylyqc7OtC.tatsu-column{width: 50%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-Bylyqc7OtC.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-half tatsu-column-image-none tatsu-column-effect-none tatsu-H1Gyc9XOYC" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-BJJVsX_F0 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-BJJVsX_F0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: center;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 20px 20px 20px 20px;color: rgba(255,255,255,1) ;}.tatsu-BJJVsX_F0.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-BJJVsX_F0 .tatsu-text-inner *{color: rgba(255,255,255,1) ;}</style> <h6>Prevents recurrent tumors in cured mice</h6> </div></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-H17159mdFR " data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 633px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 80.5687203791%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "BALB2" data-src = "https://nonabio.com/wp-content/uploads/2024/08/BALB2.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-H17159mdFR{margin: 16px 0px 0px 0px;}.tatsu-H17159mdFR .tatsu-single-image-inner{border-style: solid;max-width: 84%;}.tatsu-H17159mdFR.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-H1Gyc9XOYC.tatsu-column{width: 50.8%;}.tatsu-H1Gyc9XOYC.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-H1Gyc9XOYC > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-H1Gyc9XOYC > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-H1Gyc9XOYC > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-H1Gyc9XOYC > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-H1Gyc9XOYC.tatsu-column{width: 50%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-H1Gyc9XOYC.tatsu-column{width: 50%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-H1Gyc9XOYC.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-SkhQeFzOY0" ><style>.tatsu-SkhQeFzOY0 > .tatsu-row{margin-top: 26px;}.tatsu-SkhQeFzOY0.tatsu-row-wrap > .tatsu-row{margin-bottom: -53px;}</style><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-column-image-none tatsu-column-effect-none tatsu-rJametG_tA" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-SJSKsQOYA "><div class="tatsu-text-inner clearfix" ><style>.tatsu-SJSKsQOYA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;border-radius: 10px;padding: 20px 20px 20px 20px;color: rgba(1,36,78,1) ;}.tatsu-SJSKsQOYA.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-SJSKsQOYA .tatsu-text-inner *{color: rgba(1,36,78,1) ;}</style> <p>The B7H4×4-1BB HBICE® activates T cells in the presence of tumor cells, increasing cytokine production and cytotoxic activity. Its effectiveness is dependent on high B7H4 expression levels on tumor cells.</p> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-H1JemlFGuY0 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-H1JemlFGuY0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(1,36,78,1) ;}.tatsu-H1JemlFGuY0.tatsu-text-block-wrap{margin: 0px 0px 15px 0px;}.tatsu-H1JemlFGuY0 .tatsu-text-inner *{color: rgba(1,36,78,1) ;}</style></div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HJ_lmeKfdtR "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-HJ_lmeKfdtR.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: center;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 17px 17px 17px 17px;color: rgba(255,255,255,1) ;}.tatsu-HJ_lmeKfdtR.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-HJ_lmeKfdtR .tatsu-text-inner *{color: rgba(255,255,255,1) ;}</style> <h5 style="text-align: center;">B7H4 x 4-1BB activates human T cells in dependence of high B7H4 expression level on tumor cells</h5> </div></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-ryllmetfuKR tatsu-hide-mobile" data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 1918px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 22.3670490094%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "B7H4 x 4-1BB" data-src = "https://nonabio.com/wp-content/uploads/2024/08/B7H4-x-4-1BB.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-ryllmetfuKR .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-ryllmetfuKR.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div><div class="tatsu-single-image tatsu-module align-center tatsu-animate tatsu-image-lazyload tatsu-S1upz-lq0 tatsu-hide-tablet tatsu-hide-laptop tatsu-hide-desktop" data-animation="fadeInRight" ><div class="tatsu-single-image-inner " style="width : 747px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 172.289156627%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "Group 1000001978" data-src = "https://nonabio.com/wp-content/uploads/2024/08/Group-1000001978-3.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-S1upz-lq0 .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-S1upz-lq0.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-rJametG_tA.tatsu-column{width: 100%;}.tatsu-rJametG_tA.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-rJametG_tA > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-rJametG_tA > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-rJametG_tA > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-rJametG_tA > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-rJametG_tA.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-rJametG_tA.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-rJametG_tA.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-SyIxQxKGOtA" ><style>.tatsu-SyIxQxKGOtA > .tatsu-row{margin-top: 20px;}.tatsu-SyIxQxKGOtA.tatsu-row-wrap > .tatsu-row{margin-bottom: 0px;}</style><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-column-image-none tatsu-column-effect-none tatsu-rJwx7xYGOKA" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-Sy5wfrOKC tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-mobile tatsu-hide-tablet "><div class="tatsu-text-inner clearfix" ><style>.tatsu-Sy5wfrOKC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;border-radius: 10px;padding: 0px 20px 20px 20px;color: rgba(1,36,78,1) ;}.tatsu-Sy5wfrOKC.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-Sy5wfrOKC .tatsu-text-inner *{color: rgba(1,36,78,1) ;}</style> <h5><strong>Safety Profile</strong></h5> <p>The 4-1BB HBICE® was well tolerated in preclinical toxicity studies, with no significant adverse effects observed at therapeutic doses.</p> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-rJwx7xYGOKA.tatsu-column{width: 100%;}.tatsu-rJwx7xYGOKA.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-rJwx7xYGOKA > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-rJwx7xYGOKA > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-rJwx7xYGOKA > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-rJwx7xYGOKA > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-rJwx7xYGOKA.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-rJwx7xYGOKA.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-rJwx7xYGOKA.tatsu-column{width: 100%;}}</style></div></div></div></div><div class="tatsu-section-background-wrap"><div class = "tatsu-section-background" ></div></div><div class="tatsu-overlay tatsu-section-overlay"></div><style>.tatsu-H1QeKMdtR.tatsu-section{background-color: rgba(221,241,255,1);}.tatsu-H1QeKMdtR .tatsu-section-pad{padding: 54px 0px 62px 0px;}.tatsu-H1QeKMdtR .tatsu-section-offset-wrap{transform: translateY(-0px);}.tatsu-H1QeKMdtR > .tatsu-bottom-divider{z-index: 9999;}.tatsu-H1QeKMdtR > .tatsu-top-divider{z-index: 9999;}.tatsu-H1QeKMdtR .tatsu-section-overlay{mix-blend-mode: normal;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-H1QeKMdtR .tatsu-section-pad{padding: 44px 0px 40px 0px;}}@media only screen and (max-width: 767px) {.tatsu-H1QeKMdtR .tatsu-section-pad{padding: 17px 0px 25px 0px;}}</style></div><div class="tatsu-HJbYPUBuFR tatsu-section tatsu-bg-overlay tatsu-clearfix" data-title="" data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"105px 0px 101px 0px","l":"90px 0px 101px 0px","t":"105px 0px 109px 0px","m":"70px 0px 88px 0px"}' data-padding-top='70px'><div class="tatsu-row-wrap tatsu-wrap tatsu-row-one-col tatsu-row-has-one-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-HJxn7FrOFA" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-col tatsu-column-image-none tatsu-column-effect-none tatsu-HJ2XKB_t0" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-SJK9vruK0 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-SJK9vruK0.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;text-align: center;color: #ffffff ;}.tatsu-SJK9vruK0.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-SJK9vruK0 .tatsu-text-inner *{color: #ffffff ;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-SJK9vruK0.tatsu-text-block-wrap .tatsu-text-inner{width: 75%;}}@media only screen and (max-width: 767px) {.tatsu-SJK9vruK0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;}}</style> <h4> Next-Gen Platforms and Modalities</h4> </div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-HJ2XKB_t0.tatsu-column{width: 100%;}.tatsu-HJ2XKB_t0.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-HJ2XKB_t0 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-HJ2XKB_t0 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-HJ2XKB_t0 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-HJ2XKB_t0 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-HJ2XKB_t0.tatsu-column{width: 100%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-HJ2XKB_t0.tatsu-column{width: 100%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-HJ2XKB_t0.tatsu-column{width: 100%;}}</style></div></div></div><div class="tatsu-row-wrap tatsu-wrap tatsu-row-has-three-cols tatsu-medium-gutter tatsu-reg-cols tatsu-clearfix tatsu-SkeKwIButR" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-third tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-SJy_IrdYC" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module align-center tatsu-image-lazyload tatsu-HySvDr_KR " ><div class="tatsu-single-image-inner " style="width : 3000px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 56.2666666667%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "mRNA" data-src = "https://nonabio.com/wp-content/uploads/2024/08/mRNA-1.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-HySvDr_KR .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-HySvDr_KR.tatsu-single-image{transform: translate3d(0px,0px, 0);}.tatsu-HySvDr_KR{padding: 57px 0px 30px 0px;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-HySvDr_KR{padding: 30px 0px 0px 0px;}}@media only screen and (max-width: 767px) {.tatsu-HySvDr_KR{padding: 9px 0px 9px 0px;}}</style></div><div class="tatsu-module tatsu-text-block-wrap tatsu-SJ_cIrdKC "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-SJ_cIrdKC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: center;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 17px 17px 17px 17px;color: rgba(255,255,255,1) ;}.tatsu-SJ_cIrdKC.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-SJ_cIrdKC .tatsu-text-inner *{color: rgba(255,255,255,1) ;}</style> <h5 style="text-align: center;"><strong>mRNA-encoding Engagers/RiboHBICE®</strong></h5> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-Sk77vHdFC "><div class="tatsu-text-inner clearfix" ><style>.tatsu-Sk77vHdFC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;border-radius: 10px;padding: 20px 20px 20px 20px;color: #ffffff ;}.tatsu-Sk77vHdFC.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-Sk77vHdFC .tatsu-text-inner *{color: #ffffff ;}@media only screen and (max-width: 767px) {.tatsu-Sk77vHdFC.tatsu-text-block-wrap .tatsu-text-inner{padding: 14px 0px 0px 0px;}}</style> <p>Pioneering the next generation of engagers for enhanced delivery and efficacy. </p> <p> </p> </div></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap align-block block-center tatsu-SJO6pwYtR "><a class="tatsu-shortcode mediumbtn tatsu-button left-icon circular bg-animation-none " href="https://nonabio.com/mrna/" style= "" aria-label="Explore Now" data-gdpr-atts={} target="_blank">Explore Now</a><style>.tatsu-SJO6pwYtR .tatsu-button{background-color: rgba(238,119,31,1);color: #ffffff ;}.tatsu-SJO6pwYtR .tatsu-button:hover{background-color: rgba(235,88,22,1);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-SJy_IrdYC.tatsu-column{width: 33.33%;}.tatsu-SJy_IrdYC.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-SJy_IrdYC > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-SJy_IrdYC > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-SJy_IrdYC > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-SJy_IrdYC > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-SJy_IrdYC.tatsu-column{width: 33.33%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-SJy_IrdYC.tatsu-column{width: 33.33%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-SJy_IrdYC.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-third tatsu-column-image-none tatsu-column-effect-none tatsu-SyeJd8BdYC" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module tatsu-image-lazyload tatsu-SkvwPH_FA " ><div class="tatsu-single-image-inner " style="width : 980px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 48.9795918367%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "TCRm" data-src = "https://nonabio.com/wp-content/uploads/2024/08/TCRm.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-SkvwPH_FA .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-SkvwPH_FA.tatsu-single-image{transform: translate3d(0px,0px, 0);}.tatsu-SkvwPH_FA{padding: 65px 0px 47px 0px;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-SkvwPH_FA{padding: 65px 0px 1px 0px;}}@media only screen and (max-width: 767px) {.tatsu-SkvwPH_FA{padding: 0px 0px 0px 0px;}}</style></div><div class="tatsu-module tatsu-text-block-wrap tatsu-HkZn8SuFC "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-HkZn8SuFC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: center;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 29px 29px 29px 29px;color: rgba(255,255,255,1) ;}.tatsu-HkZn8SuFC.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-HkZn8SuFC .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (max-width: 767px) {.tatsu-HkZn8SuFC.tatsu-text-block-wrap .tatsu-text-inner{padding: 17px 17px 17px 17px;}}</style> <h5 style="text-align: center;"><strong>TCRm bsAb Engagers</strong></h5> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-SJANvBOF0 "><div class="tatsu-text-inner clearfix" ><style>.tatsu-SJANvBOF0.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;border-radius: 10px;padding: 20px 20px 20px 20px;color: #ffffff ;}.tatsu-SJANvBOF0.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-SJANvBOF0 .tatsu-text-inner *{color: #ffffff ;}@media only screen and (max-width: 767px) {.tatsu-SJANvBOF0.tatsu-text-block-wrap .tatsu-text-inner{padding: 14px 0px 0px 0px;}}</style> <p>Mimicking T-cell receptors for an even more precise targeting approach.</p> <p> </p> </div></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap align-block block-center tatsu-r10oCwttR "><a class="tatsu-shortcode mediumbtn tatsu-button left-icon circular bg-animation-none " href="https://nonabio.com/tcrm-antibody/" style= "" aria-label="Explore Now" data-gdpr-atts={} >Explore Now</a><style>.tatsu-r10oCwttR .tatsu-button{background-color: rgba(238,119,31,1);color: #ffffff ;}.tatsu-r10oCwttR .tatsu-button:hover{background-color: rgba(235,88,22,1);}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-SyeJd8BdYC.tatsu-column{width: 33.33%;}.tatsu-SyeJd8BdYC.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-SyeJd8BdYC > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-SyeJd8BdYC > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-SyeJd8BdYC > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-SyeJd8BdYC > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-SyeJd8BdYC.tatsu-column{width: 33.33%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-SyeJd8BdYC.tatsu-column{width: 33.33%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-SyeJd8BdYC.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-one-third tatsu-column-image-none tatsu-column-effect-none tatsu-BJWy_IBuKR" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module tatsu-image-lazyload tatsu-HJjPDruY0 " ><div class="tatsu-single-image-inner " style="width : 812px;" ><div class = "tatsu-single-image-padding-wrap" style = "padding-bottom : 81.7733990148%;" ></div><img class = "tatsu-gradient-border" alt = "" title = "BBB (2)" data-src = "https://nonabio.com/wp-content/uploads/2024/08/BBB-2.png" src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></div><style>.tatsu-HJjPDruY0 .tatsu-single-image-inner{border-style: solid;max-width: 100%;}.tatsu-HJjPDruY0.tatsu-single-image{transform: translate3d(0px,0px, 0);}</style></div><div class="tatsu-module tatsu-text-block-wrap tatsu-rJnT8SuYC "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-rJnT8SuYC.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: center;background: linear-gradient(90deg, rgba(46,164,221,1) 0%, rgba(32,91,149,1) 100%);border-radius: 10px;padding: 29px 29px 29px 29px;color: rgba(255,255,255,1) ;}.tatsu-rJnT8SuYC.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-rJnT8SuYC .tatsu-text-inner *{color: rgba(255,255,255,1) ;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-rJnT8SuYC.tatsu-text-block-wrap .tatsu-text-inner{padding: 37px 37px 37px 37px;}}</style> <h5 style="text-align: center;"><strong>BBB Shuttles</strong></h5> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-rJQUwHOFA "><div class="tatsu-text-inner clearfix" ><style>.tatsu-rJQUwHOFA.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;border-radius: 10px;padding: 20px 20px 20px 20px;color: #ffffff ;}.tatsu-rJQUwHOFA.tatsu-text-block-wrap{margin: 0px 0px 0px 0px;}.tatsu-rJQUwHOFA .tatsu-text-inner *{color: #ffffff ;}</style> <p>Opening new avenues for neurological therapies by shuttling brain-targeted antibodies across BBB.</p> </div></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap align-block block-center tatsu-BJpo0vYY0 "><a class="tatsu-shortcode mediumbtn tatsu-button left-icon circular bg-animation-none " href="#" style= "" aria-label="Coming Soon" data-gdpr-atts={} >Coming Soon</a><style>.tatsu-BJpo0vYY0 .tatsu-button{background-color: rgba(255,255,255,0.4);color: #ffffff ;}.tatsu-BJpo0vYY0 .tatsu-button:hover{background-color: rgba(255,255,255,0.4);}.tatsu-BJpo0vYY0.tatsu-normal-button{margin: 17px 0px 0px 0px;}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-BJWy_IBuKR.tatsu-column{width: 33.33%;}.tatsu-BJWy_IBuKR.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-BJWy_IBuKR > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-BJWy_IBuKR > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-BJWy_IBuKR > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-BJWy_IBuKR > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-BJWy_IBuKR.tatsu-column{width: 33.33%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-BJWy_IBuKR.tatsu-column{width: 33.33%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-BJWy_IBuKR.tatsu-column{width: 100%;}}</style></div></div></div></div><div class="tatsu-section-background-wrap"><div class = "tatsu-section-background" ></div></div><div class="tatsu-overlay tatsu-section-overlay"></div><style>.tatsu-HJbYPUBuFR .tatsu-section-pad{padding: 105px 0px 101px 0px;}.tatsu-HJbYPUBuFR .tatsu-section-offset-wrap{transform: translateY(-0px);}.tatsu-HJbYPUBuFR > .tatsu-bottom-divider{z-index: 9999;}.tatsu-HJbYPUBuFR > .tatsu-top-divider{z-index: 9999;}.tatsu-HJbYPUBuFR .tatsu-section-overlay{mix-blend-mode: normal;}@media only screen and (max-width:1377px) {.tatsu-HJbYPUBuFR .tatsu-section-pad{padding: 90px 0px 101px 0px;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-HJbYPUBuFR .tatsu-section-pad{padding: 105px 0px 109px 0px;}}@media only screen and (max-width: 767px) {.tatsu-HJbYPUBuFR .tatsu-section-pad{padding: 70px 0px 88px 0px;}}</style></div><div id="image-overflow-visible" class="tatsu-S1Q_Lj5h6 tatsu-section tatsu-bg-overlay tatsu-clearfix" data-title="" data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"74px 0px 10px 0px","m":"50px 0px 50px 0px","t":"40px 0px 30px 0px"}' data-padding-top='50px'><div class="tatsu-row-wrap tatsu-row-full-width tatsu-row-has-two-cols tatsu-no-gutter tatsu-reg-cols tatsu-clearfix tatsu-S1gQO8j52a" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-one-third tatsu-hide-mobile tatsu-column-image-none tatsu-column-effect-none tatsu-rkZ7uUoqha" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-single-image tatsu-module tatsu-image-lazyload tatsu-image-overflow tatsu-external-image tatsu-HJf7dIs52T " ><div class="tatsu-single-image-inner " style="" ><div class = "tatsu-single-image-padding-wrap" style = "" ></div><a href = "https://nonabio.com/mrna/" ><img class = "tatsu-gradient-border" data-src = "https://nonabio.wpenginepowered.com/wp-content/uploads/2024/01/beacon-explore-image.svg" alt =" " src ="data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR42mNkYAAAAAYAAjCB0C8AAAAASUVORK5CYII=" /></a></div><style>.tatsu-HJf7dIs52T{margin: 0px 0px -120% 0px;}.tatsu-HJf7dIs52T .tatsu-single-image-inner{border-style: solid;width: 134%;}.tatsu-HJf7dIs52T.tatsu-single-image{transform: translate3d(-50px,-295px, 0);}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-HJf7dIs52T{margin: 0px 0px 0px 0px;}.tatsu-HJf7dIs52T .tatsu-single-image-inner{width: 151%;}.tatsu-HJf7dIs52T.tatsu-single-image{transform: translate3d(-50px,-170px, 0);}}@media only screen and (max-width: 767px) {.tatsu-HJf7dIs52T .tatsu-single-image-inner{width: 100%;}.tatsu-HJf7dIs52T.tatsu-single-image{transform: translate3d(-50px,-195px, 0);}}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-rkZ7uUoqha.tatsu-column{width: 33.33%;}.tatsu-rkZ7uUoqha.tatsu-column{margin: 0px 0px -33% 0px !important;}.tatsu-rkZ7uUoqha.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-rkZ7uUoqha > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-rkZ7uUoqha > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-rkZ7uUoqha > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-rkZ7uUoqha > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-rkZ7uUoqha.tatsu-column{width: 33.33%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-rkZ7uUoqha.tatsu-column{width: 33.33%;}.tatsu-rkZ7uUoqha.tatsu-column{margin: 0px 0px -24% 0px !important;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-rkZ7uUoqha.tatsu-column{width: 100%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-two-third tatsu-animate tatsu-column-image-none tatsu-column-effect-none tatsu-B1XXO8jq2a" data-animation="fadeInRight" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-rJEm_8o5nT "><div class="tatsu-text-inner clearfix" ><style>.tatsu-rJEm_8o5nT.tatsu-text-block-wrap .tatsu-text-inner{width: 75%;text-align: left;}@media only screen and (max-width:1377px) {.tatsu-rJEm_8o5nT.tatsu-text-block-wrap .tatsu-text-inner{width: 80%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-rJEm_8o5nT.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: center;}}@media only screen and (max-width: 767px) {.tatsu-rJEm_8o5nT.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: center;}}</style> <h2 class="white-text">Explore Our Other Highlighted Technologies</h2> </div></div><div class="tatsu-module tatsu-text-block-wrap tatsu-B1HmuLoc3a tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-tablet tatsu-hide-mobile "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-B1HmuLoc3a.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;}</style> <h6>Explore our lorem ipsum</h6> </div></div><div class="tatsu-row-wrap tatsu-row-has-two-cols tatsu-no-gutter tatsu-reg-cols tatsu-inner-row-wrap tatsu-clearfix tatsu-BkIX_8o9n6" ><style>.tatsu-BkIX_8o9n6.tatsu-row-wrap > .tatsu-row{padding: 0px 10% 0px 0px;}@media only screen and (max-width:1377px) {.tatsu-BkIX_8o9n6.tatsu-row-wrap > .tatsu-row{padding: 0px 0% 0px 0px;}}@media only screen and (max-width: 767px) {.tatsu-BkIX_8o9n6.tatsu-row-wrap > .tatsu-row{padding: 0px 0% 0px 0px;}}</style><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-two-third tatsu-column-image- tatsu-column-effect- tatsu-SJDQOLj9n6" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-normal-button tatsu-button-wrap tatsu-Sy_X_Ijcn6 link-white-no-margin align-center"><a class="tatsu-shortcode mediumbtn tatsu-button right-icon circular bg-animation-none " href="/hcab-plus" style= "" aria-label="HCAb Plus Overview" data-gdpr-atts={} >HCAb Plus Overview<i class="tatsu-icon tatsu-icon-triangle-right"></i></a><style>.tatsu-Sy_X_Ijcn6 .tatsu-button{color: #ffffff ;}.tatsu-Sy_X_Ijcn6 .tatsu-button:hover{color: rgba(241,142,37,1) ;}.tatsu-Sy_X_Ijcn6.tatsu-button-wrap{margin: 2% 0px 0px 0px;}@media only screen and (max-width: 767px) {.tatsu-Sy_X_Ijcn6.tatsu-button-wrap{margin: 2% 0px 0px 0px;}}</style></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap align-block block-left tatsu-rkY7OIscha link-white-no-margin align-center"><a class="tatsu-shortcode mediumbtn tatsu-button right-icon circular bg-animation-none " href="/hbice-bispecific-multispecific/" style= "" aria-label="HBICE – Bi/Multi-specific" data-gdpr-atts={} >HBICE – Bi/Multi-specific<i class="tatsu-icon tatsu-icon-triangle-right"></i></a><style>.tatsu-rkY7OIscha .tatsu-button{color: #ffffff ;}.tatsu-rkY7OIscha .tatsu-button:hover{color: rgba(241,142,37,1) ;}.tatsu-rkY7OIscha.tatsu-normal-button{margin: 0% 0px 0px 0px;}@media only screen and (max-width: 767px) {.tatsu-rkY7OIscha.tatsu-normal-button{margin: 0% 0% 0px 0px;}.tatsu-rkY7OIscha{padding: 0px 5% 0px 0px;}}</style></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap align-block block-left tatsu-Sk5muLo9ha link-white-no-margin align-center"><a class="tatsu-shortcode mediumbtn tatsu-button right-icon circular bg-animation-none " href="/car-antibody-discovery/" style= "" aria-label="CAR-T" data-gdpr-atts={} >CAR-T<i class="tatsu-icon tatsu-icon-triangle-right"></i></a><style>.tatsu-Sk5muLo9ha .tatsu-button{color: #ffffff ;}.tatsu-Sk5muLo9ha .tatsu-button:hover{color: rgba(241,142,37,1) ;}.tatsu-Sk5muLo9ha.tatsu-normal-button{margin: 0% 0px 0px 0px;}@media only screen and (max-width: 767px) {.tatsu-Sk5muLo9ha.tatsu-normal-button{margin: 0% 0% 0px 0px;}.tatsu-Sk5muLo9ha{padding: 0px 5% 0px 0px;}}</style></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap align-block block-left tatsu-S1s7OLiq2a link-white-no-margin align-center"><a class="tatsu-shortcode mediumbtn tatsu-button right-icon circular bg-animation-none " href="https://nonabio.com/adc/" style= "" aria-label="ADC" data-gdpr-atts={} >ADC<i class="tatsu-icon tatsu-icon-triangle-right"></i></a><style>.tatsu-S1s7OLiq2a .tatsu-button{color: #ffffff ;}.tatsu-S1s7OLiq2a .tatsu-button:hover{color: rgba(241,142,37,1) ;}.tatsu-S1s7OLiq2a.tatsu-normal-button{margin: 0% 0px 0px 0px;}@media only screen and (max-width: 767px) {.tatsu-S1s7OLiq2a.tatsu-normal-button{margin: 0% 0% 0px 0px;}.tatsu-S1s7OLiq2a{padding: 0px 5% 0px 0px;}}</style></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap align-block block-left tatsu-rk3QdIi9na link-white-no-margin align-center"><a class="tatsu-shortcode mediumbtn tatsu-button right-icon circular bg-animation-none " href="/mrna" style= "" aria-label="mRNA" data-gdpr-atts={} >mRNA<i class="tatsu-icon tatsu-icon-triangle-right"></i></a><style>.tatsu-rk3QdIi9na .tatsu-button{color: #ffffff ;}.tatsu-rk3QdIi9na .tatsu-button:hover{color: rgba(241,142,37,1) ;}.tatsu-rk3QdIi9na.tatsu-normal-button{margin: 0% 0px 0px 0px;}@media only screen and (max-width:1377px) {.tatsu-rk3QdIi9na{padding: 0 0 0px 0;}}@media only screen and (max-width: 767px) {.tatsu-rk3QdIi9na.tatsu-normal-button{margin: 0% 0% 0px 0px;}.tatsu-rk3QdIi9na{padding: 0px 5% 0px 0px;}}</style></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap tatsu-BJTQdLo9n6 tatsu-hide-mobile tatsu-hide-tablet tatsu-hide-laptop tatsu-hide-desktop link-white-no-margin align-center"><a class="tatsu-shortcode mediumbtn tatsu-button right-icon circular bg-animation-none " href="https://nonabio.wpengine.com/cmc/" style= "" aria-label="CMC One Stop Solution" data-gdpr-atts={} >CMC One Stop Solution<i class="tatsu-icon tatsu-icon-triangle-right"></i></a><style>.tatsu-BJTQdLo9n6 .tatsu-button{color: #ffffff ;}.tatsu-BJTQdLo9n6 .tatsu-button:hover{color: rgba(241,142,37,1) ;}.tatsu-BJTQdLo9n6.tatsu-button-wrap{margin: 0% 0px 0px 0px;}@media only screen and (max-width:1377px) {.tatsu-BJTQdLo9n6.tatsu-button-wrap{margin: 0% 0px 0px 0px;}}</style></div><div class="tatsu-module tatsu-normal-button tatsu-button-wrap tatsu-SJCQO8o92p tatsu-hide-desktop tatsu-hide-laptop tatsu-hide-tablet tatsu-hide-mobile link-white-no-margin"><a class="tatsu-shortcode mediumbtn tatsu-button right-icon circular bg-animation-none " href="#" style= "" aria-label="Mammalian Cell Display" data-gdpr-atts={} >Mammalian Cell Display<i class="tatsu-icon tatsu-icon-triangle-right"></i></a><style>.tatsu-SJCQO8o92p .tatsu-button{color: #ffffff ;}.tatsu-SJCQO8o92p .tatsu-button:hover{color: rgba(241,142,37,1) ;}.tatsu-SJCQO8o92p.tatsu-button-wrap{margin: 0% 0px 0px 0px;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-SJCQO8o92p{padding: 0px 0% 0px 0px;}}@media only screen and (max-width: 767px) {.tatsu-SJCQO8o92p{padding: 0px 0% 0px 0px;}}</style></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-SJDQOLj9n6.tatsu-column{width: 66.67%;}.tatsu-SJDQOLj9n6.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-SJDQOLj9n6 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-SJDQOLj9n6 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-SJDQOLj9n6 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-SJDQOLj9n6 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-SJDQOLj9n6.tatsu-column{width: 66.67%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-SJDQOLj9n6.tatsu-column{width: 100%;}.tatsu-SJDQOLj9n6.tatsu-column{margin: 0px 0px 0px 0px !important;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-SJDQOLj9n6.tatsu-column{width: 100%;}.tatsu-SJDQOLj9n6.tatsu-column{margin: 0px 0px 10px 0px !important;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-column-empty tatsu-one-third tatsu-hide-mobile tatsu-hide-tablet tatsu-column-image- tatsu-column-effect- tatsu-r1Jg7d8oc36" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-r1Jg7d8oc36.tatsu-column{width: 33.33%;}.tatsu-r1Jg7d8oc36.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-r1Jg7d8oc36 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-r1Jg7d8oc36 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-r1Jg7d8oc36 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-r1Jg7d8oc36 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-r1Jg7d8oc36.tatsu-column{width: 33.33%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-r1Jg7d8oc36.tatsu-column{width: 15%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-r1Jg7d8oc36.tatsu-column{width: 100%;}}</style></div></div></div></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-B1XXO8jq2a.tatsu-column{width: 66.67%;}.tatsu-B1XXO8jq2a.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0px 5% 0px 11%;}.tatsu-B1XXO8jq2a.tatsu-column{margin: 10% 0px 0px 0px !important;}.tatsu-B1XXO8jq2a.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-B1XXO8jq2a > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-B1XXO8jq2a > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-B1XXO8jq2a > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-B1XXO8jq2a > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-B1XXO8jq2a.tatsu-column{width: 66.67%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-B1XXO8jq2a.tatsu-column{width: 66.67%;}.tatsu-B1XXO8jq2a.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0px 0% 0px 5%;}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-B1XXO8jq2a.tatsu-column{width: 100%;}.tatsu-B1XXO8jq2a.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 0px 5% 0px 5%;}.tatsu-B1XXO8jq2a.tatsu-column{margin: 0% 0px 0px 0px !important;}}</style></div></div></div></div><div class="tatsu-section-background-wrap"><div class = "tatsu-section-background" ></div></div><div class="tatsu-overlay tatsu-section-overlay"></div><style>.tatsu-S1Q_Lj5h6.tatsu-section{background-color: rgba(0,21,64,1);}.tatsu-S1Q_Lj5h6 .tatsu-section-background{background-image: url(https://nonabio.wpenginepowered.com/wp-content/uploads/2024/01/beacon-export-bkgrd.png);background-repeat: no-repeat;background-attachment: scroll;background-position: bottom right;background-size: cover;}.tatsu-S1Q_Lj5h6 .tatsu-bg-blur{background-repeat: no-repeat;background-attachment: scroll;background-position: bottom right;background-size: cover;}.tatsu-S1Q_Lj5h6 .tatsu-section-pad{padding: 74px 0px 10px 0px;}.tatsu-S1Q_Lj5h6 .tatsu-section-offset-wrap{transform: translateY(-0px);}.tatsu-S1Q_Lj5h6 > .tatsu-bottom-divider{z-index: 9999;}.tatsu-S1Q_Lj5h6 > .tatsu-top-divider{z-index: 9999;}.tatsu-S1Q_Lj5h6 .tatsu-section-overlay{mix-blend-mode: normal;}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-S1Q_Lj5h6 .tatsu-section-pad{padding: 40px 0px 30px 0px;}}@media only screen and (max-width: 767px) {.tatsu-S1Q_Lj5h6 .tatsu-section-background{background-position: center center;}.tatsu-S1Q_Lj5h6 .tatsu-bg-blur{background-position: center center;}.tatsu-S1Q_Lj5h6 .tatsu-section-pad{padding: 50px 0px 50px 0px;}}</style></div><div class="tatsu-rk1lV9jn6 tatsu-section tatsu-bg-overlay tatsu-parallax tatsu-clearfix" data-title="" data-headerscheme="background--dark"><div class='tatsu-section-pad clearfix' data-padding='{"d":"0px 0px 90px 0px","m":"60px 0px 60px 0px"}' data-padding-top='60px'><div class="tatsu-row-wrap tatsu-row-full-width tatsu-row-has-two-cols tatsu-zero-margin tatsu-no-gutter tatsu-eq-cols tatsu-hide-mobile tatsu-clearfix tatsu-ByxylNci36" ><div class="tatsu-row " ><div class="tatsu-column tatsu-bg-overlay tatsu-column-empty tatsu-one-third tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-HyWJe49i36" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ></div></div><div class = "tatsu-column-bg-image-wrap"><div class = "tatsu-column-bg-image" ></div></div><div class="tatsu-overlay tatsu-column-overlay tatsu-animate-none" ></div></div><style>.tatsu-row > .tatsu-HyWJe49i36.tatsu-column{width: 33.33%;}.tatsu-HyWJe49i36.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 10% 0% 10% 5%;}.tatsu-HyWJe49i36.tatsu-column > .tatsu-column-inner > .tatsu-column-overlay{mix-blend-mode: normal;}.tatsu-HyWJe49i36 > .tatsu-column-inner > .tatsu-top-divider{z-index: 9999;}.tatsu-HyWJe49i36 > .tatsu-column-inner > .tatsu-bottom-divider{z-index: 9999;}.tatsu-HyWJe49i36 > .tatsu-column-inner > .tatsu-left-divider{z-index: 9999;}.tatsu-HyWJe49i36 > .tatsu-column-inner > .tatsu-right-divider{z-index: 9999;}.tatsu-HyWJe49i36.tatsu-column{transform: translate3d(50px,0px, 0);z-index: 1002;}@media only screen and (max-width:1377px) {.tatsu-row > .tatsu-HyWJe49i36.tatsu-column{width: 33.33%;}}@media only screen and (min-width:768px) and (max-width: 1024px) {.tatsu-row > .tatsu-HyWJe49i36.tatsu-column{width: 40%;}.tatsu-HyWJe49i36.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 15% 0% 15% 12%;}.tatsu-HyWJe49i36.tatsu-column{transform: translate3d(20px,0px, 0);}}@media only screen and (max-width: 767px) {.tatsu-row > .tatsu-HyWJe49i36.tatsu-column{width: 100%;}.tatsu-HyWJe49i36.tatsu-column > .tatsu-column-inner > .tatsu-column-pad-wrap > .tatsu-column-pad{padding: 15% 5% 15% 5%;}}</style></div><div class="tatsu-column tatsu-bg-overlay tatsu-two-third tatsu-column-align-middle tatsu-column-image-none tatsu-column-effect-none tatsu-Hk71xN9o2T" data-parallax-speed="0" style=""><div class="tatsu-column-inner " ><div class="tatsu-column-pad-wrap"><div class="tatsu-column-pad" ><div class="tatsu-module tatsu-text-block-wrap tatsu-r1NkxV5o26 "><div class="tatsu-text-inner tatsu-align-center clearfix" ><style>.tatsu-r1NkxV5o26.tatsu-text-block-wrap .tatsu-text-inner{width: 100%;text-align: left;color: rgba(1,36,78,1) ;}.tatsu-r1NkxV5o26 .tatsu-text-inner *{color: rgba(1,36,78,1) ;}</style> <h2>Start your Harbour Mice HCAb PLUS™ Project and Accelerate your Drug Discovery Timeline</h2> <p>Having questions? Contact us at <a href="mailto:BD@nonabio.com">BD@nonabio.com</a></p> </div></div><div class="tatsu-shortcode-module tatsu-module tatsu-rkHJgVco3T " > <div class='gf_browser_unknown gform_wrapper gravity-theme gform-theme--no-framework' data-form-theme='gravity-theme' data-form-index='0' id='gform_wrapper_2' ><div id='gf_2' class='gform_anchor' tabindex='-1'></div> <div class='gform_heading'> <p class='gform_description'></p> </div><form method='post' enctype='multipart/form-data' target='gform_ajax_frame_2' id='gform_2' action='/hbice-bispecific-multispecific/#gf_2' data-formid='2' novalidate><div class='gf_invisible ginput_recaptchav3' data-sitekey='6LfU_iUqAAAAAL8adL5wRuo8ifBOkWlLBAPi4sLn' data-tabindex='0'><input id="input_eb9e6b8e87b4620ae0ba879e0d28e4c2" class="gfield_recaptcha_response" type="hidden" name="input_eb9e6b8e87b4620ae0ba879e0d28e4c2" value=""/></div> <input type='hidden' class='gforms-pum' value='{"closepopup":false,"closedelay":0,"openpopup":false,"openpopup_id":0}' 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id="popmake-880" class="pum-container popmake theme-809 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <p style="text-align: left;">Beacon® single B cell screening<span style="color: #ee771f;"></span></p> <p style="text-align: left;">Display technology<span style="color: #ee771f;"></span></p> <p style="text-align: left;">CAR-function based functional screening<span style="color: #ee771f;"></span></p> <p style="text-align: left;">Hybridoma<span style="color: #ee771f;"></span></p> <p style="text-align: left;">HCAb direct cloning screening<span style="color: #ee771f;"></span></p> <p style="text-align: left;">TCR Mimic Antibody<span style="color: #ee771f;"></span></p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-863" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-809 pum-theme-infographic-2 popmake-overlay pum-click-to-close 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top","overlay_zindex":false,"zindex":"1999999999"},"close":{"text":"","button_delay":"0","overlay_click":"1","esc_press":"1","f4_press":false},"click_open":[]}}"> <div id="popmake-863" class="pum-container popmake theme-809 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <p style="text-align: left;">Functional characterization</p> <p style="text-align: left;">Binding / Affinity</p> <p style="text-align: left;">Antibody production</p> <p style="text-align: left;">In vitro functional assay</p> <p style="text-align: left;">Developability</p> <p> </p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-852" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-809 pum-theme-infographic-2 popmake-overlay pum-click-to-close click_open" 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id="popmake-852" class="pum-container popmake theme-809 pum-responsive pum-responsive-micro responsive size-micro"> <div class="pum-content popmake-content" tabindex="0"> <p style="text-align: left;">Protein <span style="color: #ee771f;"></span></p> <p style="text-align: left;">Cell line <span style="color: #ee771f;"></span></p> <p style="text-align: left;">DNA <span style="color: #ee771f;"></span></p> <p style="text-align: left;">mRNA <span style="color: #ee771f;"></span></p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-879" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-809 pum-theme-infographic-2 popmake-overlay pum-click-to-close click_open" 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id="popmake-879" class="pum-container popmake theme-809 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <p style="text-align: left;">Target assessment<span style="color: #ee771f;"></span></p> <p style="text-align: left;">Recombinant protein<span style="color: #ee771f;"></span></p> <p style="text-align: left;">Recombinant cell-line<br /> <span style="color: #ee771f;"></span></p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-864" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-809 pum-theme-infographic-2 popmake-overlay pum-click-to-close click_open" 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id="popmake-864" class="pum-container popmake theme-809 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <p style="text-align: left;">Affinity maturation <span style="color: #ee771f;">▶</span></p> <p style="text-align: left;">Humanization<span style="color: #ee771f;">▶</span></p> <p style="text-align: left;">Fc-Engineering<span style="color: #ee771f;">▶</span></p> <p style="text-align: left;">Structure-Based Protein Design<br /> <span style="color: #ee771f;">▶</span></p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-888" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-809 pum-theme-infographic-2 popmake-overlay pum-click-to-close click_open" 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id="popmake-888" class="pum-container popmake theme-809 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <p style="text-align: left;">Stable cell line <span style="color: #ee771f;"></span></p> <p style="text-align: left;">Process development<span style="color: #ee771f;"></span></p> <p style="text-align: left;">Manufacture<span style="color: #ee771f;"></span></p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-885" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-809 pum-theme-infographic-2 popmake-overlay pum-click-to-close click_open" 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id="popmake-885" class="pum-container popmake theme-809 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <p style="text-align: left;">PK / PD <span style="color: #ee771f;"></span></p> <p style="text-align: left;">Efficacy <span style="color: #ee771f;"></span></p> <p style="text-align: left;">ADA <span style="color: #ee771f;"></span></p> <p style="text-align: left;">TOX<span style="color: #ee771f;"></span></p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-817" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-812 pum-theme-read-bio popmake-overlay pum-click-to-close click_open" data-popmake="{"id":817,"slug":"jingsong-wang-md-phd","theme_id":812,"cookies":[],"triggers":[{"type":"click_open","settings":{"cookie_name":"","extra_selectors":""}}],"mobile_disabled":null,"tablet_disabled":null,"meta":{"display":{"stackable":false,"overlay_disabled":false,"scrollable_content":false,"disable_reposition":false,"size":"medium","responsive_min_width":"0%","responsive_min_width_unit":false,"responsive_max_width":"100%","responsive_max_width_unit":false,"custom_width":"640px","custom_width_unit":false,"custom_height":"380px","custom_height_unit":false,"custom_height_auto":false,"location":"center top","position_from_trigger":false,"position_top":"100","position_left":"0","position_bottom":"0","position_right":"0","position_fixed":false,"animation_type":"fade","animation_speed":"350","animation_origin":"center top","overlay_zindex":false,"zindex":"1999999999"},"close":{"text":"","button_delay":"0","overlay_click":"1","esc_press":"1","f4_press":false},"click_open":[]}}"> <div id="popmake-817" class="pum-container popmake theme-812 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <h3 class="blue-text">Jingsong Wang, MD, PhD</h3> <h6>Chairman</h6> <p>Dr. Jingsong Wang is Chairman of Nona Biosciences. Prior to that, Dr. Wang served as Head of China R&D and Head of Translational Medicine, Asia Pacific, at Sanofi. He is a former attending physician and clinical fellow at Harvard Medical School. Dr. Wang received his Ph.D. in Molecular Pharmacology from China Pharmaceutical University and has also completed a Molecular Immunology Research Fellowship at Dr. Laurie Glimcher’s laboratory at the Harvard School of Public Health.</p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-823" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-812 pum-theme-read-bio popmake-overlay click_open" data-popmake="{"id":823,"slug":"yiping-rong-phd","theme_id":812,"cookies":[],"triggers":[{"type":"click_open","settings":{"cookie_name":"","extra_selectors":""}}],"mobile_disabled":null,"tablet_disabled":null,"meta":{"display":{"stackable":false,"overlay_disabled":false,"scrollable_content":false,"disable_reposition":false,"size":"medium","responsive_min_width":"0%","responsive_min_width_unit":false,"responsive_max_width":"100%","responsive_max_width_unit":false,"custom_width":"640px","custom_width_unit":false,"custom_height":"380px","custom_height_unit":false,"custom_height_auto":false,"location":"center top","position_from_trigger":false,"position_top":"100","position_left":"0","position_bottom":"0","position_right":"0","position_fixed":false,"animation_type":"fade","animation_speed":"350","animation_origin":"center top","overlay_zindex":false,"zindex":"1999999999"},"close":{"text":"","button_delay":"0","overlay_click":false,"esc_press":false,"f4_press":false},"click_open":[]}}"> <div id="popmake-823" class="pum-container popmake theme-812 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <h3 class="blue-text">Yiping Rong, PhD</h3> <h6>Chief Scientific Officer</h6> <p>Dr. Yiping Rong is our Chief Scientific Officer. He is a well-recognized scientist with about 20 years’ experience of biomedical research and drug discovery. Dr. Rong used to work at Sanofi, JNJ and Roche and built strong expertise in cancer biology and pharmacology. He led and contributed to >15 programs entering clinical trials. He is also involved in translational research work for a few drugs. Multiple mAb or bispecific antibodies generated from his team were out licensed to MNCs. Some highly innovative first-in-class projects are in clinical trials. He worked on apoptosis, epigenetics, immuno-oncology, and cancer cell signaling fields and led the drug discovery projects including kinase, enzyme, receptor/ligand, protein-protein-interaction targets by small molecules or monoclonal antibodies. Dr. Rong received his Ph.D. degree in Pharmacology from Case Western Reserve University (Cleveland, Ohio). He is the member of American Association of Cancer Research and has more than twenty publications in cancer research field, including <em>Nature Genetics</em>, <em>Molecular Cell</em>, <em>PNAS</em> papers. He is also the inventor of dozens of patents in drug discovery field.</p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-825" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-812 pum-theme-read-bio popmake-overlay click_open" data-popmake="{"id":825,"slug":"jiyong-zhang-phd","theme_id":812,"cookies":[],"triggers":[{"type":"click_open","settings":{"cookie_name":"","extra_selectors":""}}],"mobile_disabled":null,"tablet_disabled":null,"meta":{"display":{"stackable":false,"overlay_disabled":false,"scrollable_content":false,"disable_reposition":false,"size":"medium","responsive_min_width":"0%","responsive_min_width_unit":false,"responsive_max_width":"100%","responsive_max_width_unit":false,"custom_width":"640px","custom_width_unit":false,"custom_height":"380px","custom_height_unit":false,"custom_height_auto":false,"location":"center top","position_from_trigger":false,"position_top":"100","position_left":"0","position_bottom":"0","position_right":"0","position_fixed":false,"animation_type":"fade","animation_speed":"350","animation_origin":"center top","overlay_zindex":false,"zindex":"1999999999"},"close":{"text":"","button_delay":"0","overlay_click":false,"esc_press":false,"f4_press":false},"click_open":[]}}"> <div id="popmake-825" class="pum-container popmake theme-812 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <h3 class="blue-text">Jiyong Zhang, PhD</h3> <h6>Head of Business Development</h6> <p>Dr. Jiyong Zhang leads business development at Nona Biosciences, bringing vision and dedication to strategic growth and client satisfaction. With 15 years of experience in biotherapeutic research and development, Dr. Zhang’s understanding of market dynamics and ability to identify mission-aligned opportunities are evident.</p> <p>Before overseeing business development at Nona, Dr. Zhang played key roles at Alexion and Abbvie, contributing to antibody discovery, engineering, and bispecific antibody R&D. His scientific experiences and knowledge in biotherapeutic innovation makes him a forward-thinking strategist focused on enhancing service offerings to meet evolving client needs.</p> <p>With Dr. Zhang and his team driving business development, Nona Biosciences is poised to offer innovative solutions and unparalleled service. This solidifies the company’s position as a trusted and client-focused drug discovery partner in the dynamic landscape of biotherapeutic innovation.</p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-826" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-812 pum-theme-read-bio popmake-overlay click_open" data-popmake="{"id":826,"slug":"joe-zhao-phd","theme_id":812,"cookies":[],"triggers":[{"type":"click_open","settings":{"cookie_name":"","extra_selectors":""}}],"mobile_disabled":null,"tablet_disabled":null,"meta":{"display":{"stackable":false,"overlay_disabled":false,"scrollable_content":false,"disable_reposition":false,"size":"medium","responsive_min_width":"0%","responsive_min_width_unit":false,"responsive_max_width":"100%","responsive_max_width_unit":false,"custom_width":"640px","custom_width_unit":false,"custom_height":"380px","custom_height_unit":false,"custom_height_auto":false,"location":"center top","position_from_trigger":false,"position_top":"100","position_left":"0","position_bottom":"0","position_right":"0","position_fixed":false,"animation_type":"fade","animation_speed":"350","animation_origin":"center top","overlay_zindex":false,"zindex":"1999999999"},"close":{"text":"","button_delay":"0","overlay_click":false,"esc_press":false,"f4_press":false},"click_open":[]}}"> <div id="popmake-826" class="pum-container popmake theme-812 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <h3 class="blue-text">Joe Zhao, PhD</h3> <h6>Vice President, Head of External Innovation</h6> <p>Dr. Joe Zhao is Vice President and Head of External Innovation of Nona Biosciences. Joe holds a BS from Fudan University and a PhD from University of Delaware, followed by postdoctoral trainings at Lankenau Medical Center and Zeneca Pharmaceuticals. Prior to joining Harbour BioMed, he was in small biotechs (Pharmacopeia and Ligand Pharmaceuticals) and large MNC (BMS). 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He graduated from Bethune Medical University with Bachelor Degree of Medicine. He has over 30 years’ experience in antibody technology platform establishment, antibody discovery and discovery team management experience. Previously he worked in Syntron Bioresearch Inc as R&D manager, Strategic Diagnostic Inc as product development supervisor, Rockland Immunochemical Inc as Manager of Monoclonal Antibody service and product development, GenScript Ltd as vice president of Antibody Division, Shanghai ChemPartner as vice president of Biologics Discovery.</p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-828" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-812 pum-theme-read-bio popmake-overlay click_open" data-popmake="{"id":828,"slug":"yun-he-phd","theme_id":812,"cookies":[],"triggers":[{"type":"click_open","settings":{"cookie_name":"","extra_selectors":""}}],"mobile_disabled":null,"tablet_disabled":null,"meta":{"display":{"stackable":false,"overlay_disabled":false,"scrollable_content":false,"disable_reposition":false,"size":"medium","responsive_min_width":"0%","responsive_min_width_unit":false,"responsive_max_width":"100%","responsive_max_width_unit":false,"custom_width":"640px","custom_width_unit":false,"custom_height":"380px","custom_height_unit":false,"custom_height_auto":false,"location":"center top","position_from_trigger":false,"position_top":"100","position_left":"0","position_bottom":"0","position_right":"0","position_fixed":false,"animation_type":"fade","animation_speed":"350","animation_origin":"center top","overlay_zindex":false,"zindex":"1999999999"},"close":{"text":"","button_delay":"0","overlay_click":false,"esc_press":false,"f4_press":false},"click_open":[]}}"> <div id="popmake-828" class="pum-container popmake theme-812 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <h3 class="blue-text">Yun He, PhD</h3> <h6>Chief Technology Officer</h6> <p>Dr. Yun He is Chief Technology Officer of Nona Biosciences. Before Nona Biosciences spun off from Harbour BioMed, Dr. He served as Head of Antibody Technology at Harbour BioMed. During his tenure there, Dr. He contributed to multiple discovery programs and led the team in establishing HBICE® platform. Prior to joining Harbour BioMed, Dr. He was an Investigator at Biologics Center in Novartis, where he was responsible for antibody engineering and bioinformatics. Prior to that, Dr. He was the group leader of Bioinformatics at GenScript. 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Beginning his professional journey as a Scientist II at MedImmune, Dr. Bao later transitioned to Sanofi, where he served as a Principal Scientist. Following this, he joined Harbour BioMed, where he led a team dedicated to therapeutic antibody development utilizing the Harbour Mice® platform. 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He is a respected leader in drug discovery with substantial roles under his belt, including Research Head, Chief Scientific Officer (CSO), and Chief Executive Officer (CEO) positions at various pharmaceutical or biotech companies. Dr. Arkinstall served as CEO of Elstar Therapeutics and Revitope Oncology, companies advancing novel classes of multi-specific antibody-based cancer drugs. He previously was also the CSO of Kymab, an antibody therapeutics company founded in Cambridge, UK, prior to which he spent 16 years in progressively senior research leadership roles at EMD (Merck) Serono, and its associated entities across Europe and the United States.</p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-832" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-812 pum-theme-read-bio popmake-overlay click_open" data-popmake="{"id":832,"slug":"frank-grosveld-phd","theme_id":812,"cookies":[],"triggers":[{"type":"click_open","settings":{"cookie_name":"","extra_selectors":""}}],"mobile_disabled":null,"tablet_disabled":null,"meta":{"display":{"stackable":false,"overlay_disabled":false,"scrollable_content":false,"disable_reposition":false,"size":"medium","responsive_min_width":"0%","responsive_min_width_unit":false,"responsive_max_width":"100%","responsive_max_width_unit":false,"custom_width":"640px","custom_width_unit":false,"custom_height":"380px","custom_height_unit":false,"custom_height_auto":false,"location":"center top","position_from_trigger":false,"position_top":"100","position_left":"0","position_bottom":"0","position_right":"0","position_fixed":false,"animation_type":"fade","animation_speed":"350","animation_origin":"center top","overlay_zindex":false,"zindex":"1999999999"},"close":{"text":"","button_delay":"0","overlay_click":false,"esc_press":false,"f4_press":false},"click_open":[]}}"> <div id="popmake-832" class="pum-container popmake theme-812 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <h3 class="blue-text">Frank Grosveld, PhD</h3> <h6>Academy Professor of Cell Biology, Erasmus Medical Center, Rotterdam</h6> <p>Dr. Grosveld is Co-founder and CSO of Harbour Antibodies and the inventor of Harbour Mice<sup>®</sup>, Professor and former Head of Department of Cell Biology and Department of Clinical Genetics at Erasmus University Medical Center, Rotterdam, a fellow of Royal Society and a member of Royal Netherlands Academy of Arts and Sciences. Dr. Grosveld’s research on the control of globin gene expression has been selected as one of the top ten achievements of Medical Research Council (UK) (MRC) in the 20th century by Higher Education and Research Opportunities in the U.K. Dr. Grosveld was awarded the Louis-Jeantet Prize for Medicine in 1991, the Spinozapremie (Spinoza Prize) in 1995.</p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-833" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-812 pum-theme-read-bio popmake-overlay click_open" data-popmake="{"id":833,"slug":"robert-kamen-phd","theme_id":812,"cookies":[],"triggers":[{"type":"click_open","settings":{"cookie_name":"","extra_selectors":""}}],"mobile_disabled":null,"tablet_disabled":null,"meta":{"display":{"stackable":false,"overlay_disabled":false,"scrollable_content":false,"disable_reposition":false,"size":"medium","responsive_min_width":"0%","responsive_min_width_unit":false,"responsive_max_width":"100%","responsive_max_width_unit":false,"custom_width":"640px","custom_width_unit":false,"custom_height":"380px","custom_height_unit":false,"custom_height_auto":false,"location":"center top","position_from_trigger":false,"position_top":"100","position_left":"0","position_bottom":"0","position_right":"0","position_fixed":false,"animation_type":"fade","animation_speed":"350","animation_origin":"center top","overlay_zindex":false,"zindex":"1999999999"},"close":{"text":"","button_delay":"0","overlay_click":false,"esc_press":false,"f4_press":false},"click_open":[]}}"> <div id="popmake-833" class="pum-container popmake theme-812 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <h3 class="blue-text">Robert Kamen, PhD</h3> <h6>Venture Partner, Third Rock Ventures</h6> <p>Dr. Kamen is a Venture Partner at Third Rock Ventures. In 2005, he co-founded BioAssets Development Corporation and served as its Chairman. He currently serves as an independent non-executive Director of Harbour BioMed and a director of Jounce Therapeutics (NASDAQ:JNCE). He was previously a director of Neon Therapeutics and Harbour Antibodies. Earlier in his career, he was senior vice president of scientific affairs at the pioneering biotechnology firm named Genetics Institute, Inc. Dr. Kamen received his bachelor’s degree in biophysics from Amherst College, a Ph.D. in biochemistry and molecular biology from Harvard University Graduate School of Arts and Sciences. 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Dr. Kramer previously served as Vice President and Head of Discovery for Oncology Therapeutics at Janssen Research & Development, LLC (the Pharmaceutical Division of Johnson and Johnson), where he was responsible for leading Global Discovery, focusing on aberrant signaling cascades in tumor cells, as well as epigenetic reprogramming and tumor immunology using both small molecule and protein-based large molecule approaches. Prior to joining Janssen Research & Development, LLC, Dr. Kramer served as VP Drug Discovery and Research for Bristol-Myers Squibb (BMS), where he provided scientific leadership and strategic oversight for many pre-clinical Oncology and Immunology programs and projects that entered development. Dr. Kramer was previously an Assistant Professor at Harvard Medical School. Dr. Kramer received his Ph.D. in pharmacology from the University of Vermont and completed his post-doctoral fellowship in Oncology at the National Cancer Institute, National Institutes of Health.</p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-835" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-812 pum-theme-read-bio popmake-overlay click_open" data-popmake="{"id":835,"slug":"peter-moesta-phd","theme_id":812,"cookies":[],"triggers":[{"type":"click_open","settings":{"cookie_name":"","extra_selectors":""}}],"mobile_disabled":null,"tablet_disabled":null,"meta":{"display":{"stackable":false,"overlay_disabled":false,"scrollable_content":false,"disable_reposition":false,"size":"medium","responsive_min_width":"0%","responsive_min_width_unit":false,"responsive_max_width":"100%","responsive_max_width_unit":false,"custom_width":"640px","custom_width_unit":false,"custom_height":"380px","custom_height_unit":false,"custom_height_auto":false,"location":"center top","position_from_trigger":false,"position_top":"100","position_left":"0","position_bottom":"0","position_right":"0","position_fixed":false,"animation_type":"fade","animation_speed":"350","animation_origin":"center top","overlay_zindex":false,"zindex":"1999999999"},"close":{"text":"","button_delay":"0","overlay_click":false,"esc_press":false,"f4_press":false},"click_open":[]}}"> <div id="popmake-835" class="pum-container popmake theme-812 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <h3 class="blue-text">Peter Moesta, PhD</h3> <h6>Former CEO, Adello Biologics</h6> <p>Peter Moesta, Ph.D., oversaw the development, production and worldwide launch of important medicines, such as Humira, Yervoy and Opdivo. Dr. Moesta previously served in executive roles at Bristol-Myers Squibb.</p> </div> <button type="button" class="pum-close popmake-close" aria-label="Close"> × </button> </div> </div> <div id="pum-836" role="dialog" aria-modal="false" class="pum pum-overlay pum-theme-812 pum-theme-read-bio popmake-overlay click_open" data-popmake="{"id":836,"slug":"zhigang-tian-phd","theme_id":812,"cookies":[],"triggers":[{"type":"click_open","settings":{"cookie_name":"","extra_selectors":""}}],"mobile_disabled":null,"tablet_disabled":null,"meta":{"display":{"stackable":false,"overlay_disabled":false,"scrollable_content":false,"disable_reposition":false,"size":"medium","responsive_min_width":"0%","responsive_min_width_unit":false,"responsive_max_width":"100%","responsive_max_width_unit":false,"custom_width":"640px","custom_width_unit":false,"custom_height":"380px","custom_height_unit":false,"custom_height_auto":false,"location":"center top","position_from_trigger":false,"position_top":"100","position_left":"0","position_bottom":"0","position_right":"0","position_fixed":false,"animation_type":"fade","animation_speed":"350","animation_origin":"center top","overlay_zindex":false,"zindex":"1999999999"},"close":{"text":"","button_delay":"0","overlay_click":false,"esc_press":false,"f4_press":false},"click_open":[]}}"> <div id="popmake-836" class="pum-container popmake theme-812 pum-responsive pum-responsive-medium responsive size-medium"> <div class="pum-content popmake-content" tabindex="0"> <h3 class="blue-text">Zhigang Tian, PhD</h3> <h6>Academician of Chinese Academy of Engineering,<br /> Member of Academia Europaea Professor, School of Life Sciences,<br /> Dean, School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science & Technology of China (USTC),<br /> Director, Institute of Immunology,USTC,<br /> Director, The Key Lab of Innate Immunity and Chronic Disease, Chinese Academy of Science</h6> <p>Dr. Tian is an academician of Chinese Academy of Engineering, a member of Academia Europaea and a medical immunologist. Currently, he is a professor at University of Science and Technology of China (USTC), where he also works as Dean at School of Basic Medical Sciences, and Director at Institute of Immunology. He is also the Director of the Key Lab of Innate Immunity and Chronic Diseases of Chinese Academy of Science.</p> <p>Dr. Tian was awarded with the National Science Fund for Distinguished Young Scholars. He is the academic leader of Chang Jiang Scholars Program as well as the Innovation Research Program of National Natural Science Foundation of China. 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