Immunoassays for Immuno-Oncology Research

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class="col-md-12"> <div> <div id="block-bio-techne-global-breadcrumbs" class="system_breadcrumb_block"> <nav role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/applications">Applications</a> </li> <li> Immunoassays For Immuno-Oncology </li> </ol> </nav> </div> </div> </div> </div> <div class="row"> <div class="col-md-12"> <main> <section class="section"> <div> <div id="block-bio-techne-global-content" class="system_main_block"> <article> <div> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h1>Immunoassays for Immuno-Oncology Research </h1></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <a href="https://www.bio-techne.com/applications/immunoassays" title="Bio-Techne's Immunoassay Solutions" > <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/luminex-workflow-screening-validation-multiplex-single-plex-assays.png" alt="Immunoassay screening to validation Workflow" loading="lazy" > </a> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>From early-stage multiplex biomarker discovery, to target analyte validation, to the study of cytokine release syndrome (CRS), Bio-Techne has a wide range of multiplex, single analyte, and automated immunoassays to suit your needs.</p> <p><strong>Why Bio-Techne?</strong></p> <ul> <li>Unwavering commitment to quality and consistency</li> <li>More than 30 years of experience in immunoassay development and manufacturing</li> <li>Extensive range of target analytes in multiple immunoassay formats</li> </ul></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_call_to_action_global"> <a href="/applications/immunoassays" class="btn btn-primary" type="link"> Bio-Techne's Immunoassay Solutions </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/luminex-3d-card.jpg" alt="Luminex bead antibody binding analyte in Luminex multiplex assay" loading="lazy" > </div> <h3 class="card_title_htag"> <div><h4>Multiplex with R&D Systems™ Luminex<sup>®</sup> Assays</h4></div> </h3> <div class="card_description flex-grow-1"> <div><p>R&D Systems Luminex assays are highly flexible- enabling you to select only the analytes you want to interrogate. </p> <p><strong><a href="/search?keywords=cytokine%20luminex&common_name=Multiplex%20Cytokine%20Assay%20Kits">Cytokine Panels</a></strong></p> <p><a href="/search?keywords=immunechecktargets&category_attr=Luminex%20Assays"><strong>Immune Checkpoint Assays</strong></a></p> <p><a href="/reagents/luminex-assays/early-cancer-detection"><strong>Meeting the Challenge of Early Cancer Detection</strong></a></p> <p><a href="/p/luminex-assays/human-immuno-oncology-panel-1-luminex-performance-premix-kit_fcstm24"><strong>Human Immuno-Oncology Panel 1 - Now Available</strong></a></p></div> </div> <div class="card-bottom-link"></div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/elisa-3d-card.jpg" alt="Sandwich ELISA antibody binding antigen in ELISA kit plate well" loading="lazy" > </div> <h3 class="card_title_htag"> <div><h4>Single Analyte Analysis with Quantikine™ ELISAs</h4></div> </h3> <div class="card_description flex-grow-1"> <div><p>Quantikine ELISAs are the most referenced ELISA kits on the market. Choose from our wide range of over 600 assays across seven species.<br>  </p> <p><strong><a href="/search?keywords=cytokine&category_attr=ELISA%20Kits&sub_category=Quantikine%20Colorimetric%20Sandwich%20ELISAs">Cytokine ELISAs</a></strong></p> <p><strong><a href="/search?keywords=immunechecktargets&sub_category=Quantikine%20Colorimetric%20Sandwich%20ELISAs">Immune Checkpoint ELISAs</a></strong></p> <ul> <li><a href="/p/elisa-kits/human-pd-1-quantikine-elisa-kit_dpd10"><strong>PD-1</strong></a></li> <li><a href="/p/elisa-kits/human-cynomolgus-monkey-pd-l1-b7-h1-quantikine-elisa-kit_db7h10"><strong>PD-L1</strong></a></li> <li><a href="/p/elisa-kits/human-ctla-4-quantikine-hs-elisa-kit_hsct40"><strong>CTLA-4</strong></a></li> </ul></div> </div> <div class="card-bottom-link"></div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/products/ella-simple-plex-assay-cartridges-1.png" alt="Single, Multianalyte or Multiplex Assays on Automated ELISA System Ella" loading="lazy" > </div> <h3 class="card_title_htag"> <div><h4>Get Real-Time Data with Simple Plex™ Assays</h4></div> </h3> <div class="card_description flex-grow-1"> <div><p>Save time and precious sample with Simple Plex assays on the automated Ella platform. Ella reduces user error and delivers results in 90 minutes. Learn more at proteinsimple.com:</p> <p><strong><a href="/resources/instrument-applications/simple-plex-cancer-biomarkers">Cancer Immunoassays</a></strong></p> <p><strong><a href="/resources/instrument-applications/simple-plex-cell-therapy">Cell Therapy Immunoassays</a></strong></p> <p><a href="/reagents/simple-plex-immunoassays/assay-menu"><strong>See All Immunoassays</strong></a></p></div> </div> <div class="card-bottom-link"></div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph-image-banner banner_wrapper"> <div class="banner_background_image" data-bgimage="https://resources.bio-techne.com/images/webinar/LP_images/immuno-oncology-research-lp-hero-background.png" style="background-repeat: no-repeat"> <div class="text_align_center"> <div><h2>Two Sides of a Coin: CTLA-4 in Immunotherapy and Autoimmunity</h2></div> <div><p>CTLA-4 can be a double-edged sword in the fight against cancer. Get accurate and consistent CTLA-4 data with Quantikine ELISAs.</p></div> <a href="/reagents/elisa-kits/immune-checkpoint-assays" > <button type="button" class="btn btn-primary"> Explore Immunoassays for CTLA-4 and Immune Checkpoint Research </button> </a> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-6"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/ELISASolo03.png" alt="Immunoassays, ELISA kits and Luminex assays" loading="lazy" > </div> </div> </div> <h3 class="card_title_htag"> <div><h4>DuoSet™ Development ELISAs</h4></div> </h3> <div class="card_description flex-grow-1"> <div><p>A customizable development ELISA to meet your specific research needs. DuoSets are an economical, flexible alternative for the experienced ELISA-user.</p> <p><strong><a href="/search?keywords=cytokine&category_attr=ELISA%20Kits&sub_category=DuoSet%20ELISA%20Development%20Systems">Cytokine Assays</a> | <a href="/search?keywords=immunechecktargets&category_attr=ELISA%20Kits&sub_category=DuoSet%20ELISA%20Development%20Systems">Immune Checkpoint Assays</a></strong></p> <p><strong><a href="/search?keywords=CTLA-4&category_attr=ELISA%20Kits&sub_category=DuoSet%20ELISA%20Development%20Systems">CTLA-4</a></strong> | <strong><a href="/search?keywords=IDO&category_attr=ELISA%20Kits">IDO</a> | <a href="/search?keywords=PD-1&category_attr=ELISA%20Kits&sub_category=DuoSet%20ELISA%20Development%20Systems">PD-1</a> |</strong> <strong><a href="/search?keywords=PD-L1&category_attr=ELISA%20Kits&sub_category=DuoSet%20ELISA%20Development%20Systems">PD-L1</a></strong></p></div> </div> <div class="card-bottom-link"></div> </div> </div> </div> <div class="col-md-6"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/proteome-sized.png" alt="Proteome Profiler antibody arrays" loading="lazy" > </div> </div> </div> <h3 class="card_title_htag"> <div><h4>Proteome Profiler™ Antibody Arrays</h4></div> </h3> <div class="card_description flex-grow-1"> <div><p>Proteome Profiler Antibody Arrays are the economical discovery choice for early-stage immuno-oncology research. Measure more than 100 proteins in a single sample!</p> <p><strong><a href="/search?keywords=angiogenesis&category_attr=Proteome%20Profiler%20Antibody%20Arrays">Angiogenesis Arrays</a> | <a href="/search?keywords=cancer&category_attr=Proteome%20Profiler%20Antibody%20Arrays">Cancer Arrays</a></strong></p> <p><strong><a href="/search?keywords=cytokine&category_attr=Proteome%20Profiler%20Antibody%20Arrays">Cytokine Arrays</a> | <a href="/search?keywords=immunechecktargets&category_attr=Proteome%20Profiler%20Antibody%20Arrays">Immuno-oncology Arrays</a></strong></p></div> </div> <div class="card-bottom-link"></div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-6"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/applications/fore-halfcol-instrument-603x422.png" alt="Jess and Peggy Sue instruments" loading="lazy" > </div> </div> </div> <h3 class="card_title_htag"> <div><h4>Simple Western™ Assays</h4></div> </h3> <div class="card_description flex-grow-1"> <div><p>Simple Western assays are from ProteinSimple, a Bio-Techne brand. Learn more on ProteinSimple.com and Bio-Techne.com.</p> <p>Characterize proteins by <a href="/instruments/simple-western/simple-western-assays-charge-based-separation">charge </a>or <a href="/instruments/simple-western/simple-western-assays-utilizing-size-based-separation">size </a>with gel-free, blot-free, fully automated Western analysis. Get quantitative and reproducible results on up to 25 samples in 3 hours with only 3 µL of starting material, or process 96 samples overnight with 5 µL of starting material - all without user intervention!</p> <p><strong><a href="/instruments/simple-western">Learn More About Simple Western</a> |<a href="/p/instruments/simple-western/request-quote"> Request Pricing</a></strong></p> <p><strong><a href="/resources/instrument-applications/advanced-western-blotting-solutions-for-oncology">Simple Western Solutions for Cancer & Immuno-Oncology</a></strong></p></div> </div> <div class="card-bottom-link"></div> </div> </div> </div> <div class="col-md-6"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/neuroscience-milo-focus-525x525.png" alt="Single-cell western instrument Milo" loading="lazy" > </div> </div> </div> <h3 class="card_title_htag"> <div><h4>Milo™: Single-Cell Western Assays</h4></div> </h3> <div class="card_description flex-grow-1"> <div><p>Single-Cell Western assays are from ProteinSimple, a Bio-Techne brand. Learn more on ProteinSimple.com and Bio-Techne.com.</p> <p>Analyze ~1000 single cells at a time to reveal heterogeneity in your sample that would go unnoticed by <a href="/applications/western-blotting">traditional Western blot</a>. Profile the tumor microenvironment, track stem cell differentiation, <a href="/resources/instrument-applications/single-cell-westerns-to-validate-single-cell-rna-seq-data-milo">validate RNAseq data</a>, and more.</p> <p><strong><a href="/instruments/single-cell-western">Learn More About Single-Cell Western</a>| <a href="/p/instruments/single-cell-western/request-quote?productName=Milo&catalogNumber=P100">Request Pricing</a></strong></p> <p><strong><a href="/resources/instrument-applications/advanced-western-blotting-solutions-for-oncology">Single-Cell Western Solutions for Cancer & Immuno-Oncology</a></strong></p></div> </div> <div class="card-bottom-link"></div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4 p-3"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <a href="https://www.bio-techne.com/resources/literature/t-cell-therapies-ebook" title="Request Your T Cell-Based Therapies eBook" target="_self" > <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/t-cell-ebook-featured-203x150.png" alt="image of T Cell-Based Therapies eBook" loading="lazy" > </a> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>This new eBook provides an overview of several biological and manufacturing challenges facing the development and production of T cell therapies. It follows with examples of how Bio-Techne products and services can address these challenges at each stage of the process.</p></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_call_to_action_global"> <a href="/resources/literature/t-cell-therapies-ebook" class="btn btn-primary" type="link"> Request Your T Cell-Based Therapies eBook </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <h2>Featured Immunoassays for Immuno-Oncology Research</h2> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/graphs/sampledilution-chart.jpg" alt="sampledilution-chart" loading="lazy" > </div> </div> </div> <h3 class="card_title_htag"> <div><h4>Immune Checkpoint Quantikine ELISAs</h4></div> </h3> <div class="card_description flex-grow-1"> <div><ul> <li><a href="/p/elisa-kits/human-ctla-4-quantikine-hs-elisa-kit_hsct40"><strong>NEW! Human CTLA-4 Quantikine High Sensitivity ELISA</strong></a></li> <li><a href="/p/elisa-kits/human-cynomolgus-monkey-pd-1-horseradish-peroxidase-conjugated-antibody_dpd10"><strong>NEW! Human PD-1 Quankine ELISA Kit</strong></a></li> </ul></div> </div> <div class="card-bottom-link"></div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/graphs/human-immuno-therapy-luminex-panel-chart.jpg" alt="human-immuno-therapy-luminex-panel-chart" loading="lazy" > </div> </div> </div> <h3 class="card_title_htag"> <div><h4>Monitor CRS with Luminex Panels</h4></div> </h3> <div class="card_description flex-grow-1"> <div><ul> <li><a href="/p/luminex-assays/human-immunotherapy-magnetic-luminex-performance-assay-24-plex-fixed-panel_lktm010"><strong>Human Immunotherapy 24-Plex Fixed Panel </strong></a></li> <li><a href="/p/luminex-assays/human-immuno-oncology-panel-1-luminex-performance-premix-kit_fcstm24"><strong>Human Immuno-oncology Panel One 14-plex Premixed Panel</strong></a></li> <li><a href="/p/luminex-assays/human-xl-cytokine-magnetic-luminex-performance-assay-45-plex-fixed-panel_lktm014"><strong>Human XL Cytokine Fixed Panel</strong></a></li> </ul></div> </div> <div class="card-bottom-link"></div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/graphs/calibration-curve-chart.jpg" alt="calibration-curve-chart" loading="lazy" > </div> </div> </div> <h3 class="card_title_htag"> <div><h4>Simple Plex Immune Checkpoint Immunoassay</h4></div> </h3> <div class="card_description flex-grow-1"> <div><ul> <li><a href="/p/simple-plex/simple-plex-human-b7-h1-pd-l1-cartridge_spckb-ps-003468"><strong>New! Simple Plex Human PD-L1/B7-H1 2nd Generation Cartridge</strong></a></li> </ul></div> </div> <div class="card-bottom-link"></div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <h2>Custom Immunoassay Services</h2> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/services/custom-elisa-services" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/elisaKits_IVDAssayPage.jpg" alt="Bio-Techne’s ELISA kits from its R&D Systems brand, including the most referenced Quantikine ELISA kits." loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/services/custom-elisa-services" > <h3 class="card_title_htag"> <div><h3>Custom ELISA Services</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Take advantage of our decades of ELISA development experience to accelerate your custom project.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/services/custom-elisa-services" > Let's Discuss Your Custom and Bulk Needs </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/services/custom-luminex-services" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/luminexPlexAssays_IVDAssayPage.jpg" alt=": Bio-Techne’s Luminex Assay from its R&D Systems brand combines accuracy and performance with the breadth of content." loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/services/custom-luminex-services" > <h3 class="card_title_htag"> <div><h3>Custom Luminex Services</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Utilize our comprehensive collection of in-house proteins and antibodies to create a custom Luminex panel to fit your research needs.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/services/custom-luminex-services" > Let's Discuss Your Multiplexing Needs </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/services/custom-simple-plex-services" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/simplePlexAssays_IVDAssayPage.jpg" alt="Bio-Techne’s Simple Plex Assays from its ProteinSimple brand are the next generation of ELISAs." loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/services/custom-simple-plex-services" > <h3 class="card_title_htag"> <div><h3>Custom Simple Plex Services</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Save development time, conserve your budget, and accelerate your multiplexing capabilities by utilizing our decades of experience.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/services/custom-simple-plex-services" > Let's Discuss Your Custom Simple Plex Needs </a> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2>Additional Immuno-Oncology Content</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4 p-3"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/elisa-hs-immunoassays-ifn-gamma-secretion-cytokine-storm-app-note.jpg" alt="ELISA High Sensitivity Immunoassays" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h2>Quantify IFN-Gamma with Confidence</h2></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Cytokine Release Syndrome (CRS) is an adverse effect of cellular therapy. Interferon gamma (IFN-gamma) secretion can be an early and prominent feature of CRS. Download this application note to see how <a href="/p/elisa-kits/human-ifn-gamma-quantikine-hs-elisa-kit_hsdif0">Quantikine High Sensitivity ELISA</a>s are used to detect IFN-gamma in serum and plasma.</p></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_call_to_action_global"> <a href="https://resources.rndsystems.com/images/site/rnd-systems-an-ifngamma-ifqnuantikine-hs.pdf" class="btn btn-primary" type="link"> Download the IFN-Gamma Application Note </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4 p-3"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/images/webinar/LP_images/immuno-oncology-cancer-cell-2-v2.png" alt="Immuno-oncology research cell molecule" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h2>Proteins for Immune Checkpoint Research</h2></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Immune checkpoint proteins play a central role in regulating the activities of multiple immune cell types and are being investigated as some of the most promising targets for cancer immunotherapy research. Bio-Techne offers an extensive range of R&D Systems™ immune checkpoint proteins for studying common and emerging immune checkpoint targets, including <a href="/reagents/proteins/pd-l1-pd-l2-pd-1-proteins">PD-1</a>, <a href="/reagents/proteins/b7-cd28-ctla-4-proteins">CTLA-4</a>, <a href="/reagents/proteins/lag-3-protein">LAG-3</a>, <a href="/reagents/proteins/tigit-protein">TIGIT</a>, <a href="/reagents/proteins/tim-3-protein">TIM-3</a>, <a href="/reagents/proteins/immune-checkpoint-proteins/butyrophilin">butyrophilins</a>, and <a href="/reagents/proteins/lilr-proteins">LILR</a> family members.</p></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_call_to_action_global"> <a href="/reagents/proteins/immune-checkpoint-proteins" class="btn btn-primary" type="link"> Explore Our Selection of Immune Checkpoint Proteins </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4 p-3"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/images/design/dw_downres_io-ebbok_STRY0032592.png" alt="Immuno-Oncology Checkpoint Proteins" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h2>Current and Emerging Immune Checkpoint Targets for Immuno-Oncology Research</h2></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Download the eBook to learn about existing and emerging immune checkpoint targets.</p></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_call_to_action_global"> <a href="/resources/literature/current-and-emerging-immune-checkpoint-targets-immuno-oncology-research-ebook" class="btn btn-primary" type="link"> Request the eBook </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-3-media-to-text paragraph--view-mode--default mb-4 p-3"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--25-75"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/wes-and-milo-thumb.png" alt="Wes and Milo Appnote Thumbnail" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:1_3_media_to_text:field_header_2_global"> <div><h2>Profile the Tumor Microenvironment with Quantitative Protein Analysis</h2></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Learn how <a href="/instruments/simple-western">Simple Western</a> and <a href="/instruments/single-cell-western">Single-Cell Western</a> partner to get you critical answers to study the tumor microenvironment, including the type of immune cell populations that are present and the percentage of cells that make up a specific immune cell subtype.</p></div> </div> <div class="field_block:paragraph:1_3_media_to_text:field_call_to_action_global"> <a href="/resources/literature/wes-milo-synergize-profile-immune-cell-populations-tumor-microenvironment" class="btn btn-primary" type="link"> Download the Tumor Microenvironment Application Note </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <h2>Resources for Immuno-Oncology Research</h2> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/research-areas/immuno-oncology/immuno-oncology-resources" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; 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