Genetic science | List of High Impact Articles

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AngII-Induced Adipocyte Dysfunction</a> <p class="m-0 clearfix"><a href="https://www.ncbi.nlm.nih.gov/pmc?term=%22J%20Clin%20Med%20Sci%22[jour]" target="_blank"><span class="btn btn-warning btn-xs float-right">View More »</span></a></p></p> </div> </div> <div class="card mb-3"> <div class="card-header custom-header"> <h6><a target="_blank" href="https://scholar.google.com/citations?hl=en&view_op=list_works&gmla=AHoSzlXBmLYqSXSHMZSpIBdA0iov0SfMiySYzN1JVnx7jsdmzB3kblHioyFDdKMDMuJt3U4kq_6ulgTJXd6Y0usmW7m1OzSPk6MbgRcnvo0&user=yGkJoOMAAAAJ" title="Click here">Google Scholar citation report</a></h6> </div> <div class="card-body custom-body"> <h6 style="font-weight:bold;">Citations : 64</h6> <p><a target="_blank" href="https://scholar.google.com/citations?hl=en&view_op=list_works&gmla=AHoSzlXBmLYqSXSHMZSpIBdA0iov0SfMiySYzN1JVnx7jsdmzB3kblHioyFDdKMDMuJt3U4kq_6ulgTJXd6Y0usmW7m1OzSPk6MbgRcnvo0&user=yGkJoOMAAAAJ" title="Click here">Journal of Clinical and Medical Sciences received 64 citations as 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style="font-family:"Calibri","sans-serif""><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Genomics is the branch of molecular biology that focuses on the structure, function, evolution, and mapping of genomes—the complete set of DNA in an organism, including all of its genes. It involves the study of the entire genome of organisms to understand how genes interact, influence traits, and contribute to health and disease. Genomics encompasses a broad range of scientific disciplines and techniques, and it plays a crucial role in advancing personalized medicine, evolutionary biology, and biotechnology. Key Areas of Genomics:</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:12.0pt"><span style="font-family:"Cambria","serif"">Structural Genomics</span></span></b></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Purpose:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Aims to determine the three-dimensional structures of proteins and other biomolecules encoded by genes. Understanding these structures helps in elucidating protein functions and interactions.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Techniques:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Includes X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and cryo-electron microscopy.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:12.0pt"><span style="font-family:"Cambria","serif"">Functional Genomics</span></span></b></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Purpose:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Studies the roles and functions of genes and their products (proteins and RNA). Functional genomics explores how genes are regulated and how they contribute to cellular processes and organismal traits.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Techniques:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Includes gene expression profiling (e.g., RNA sequencing), gene knockout/knockdown studies, and proteomics.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:12.0pt"><span style="font-family:"Cambria","serif"">Comparative Genomics</span></span></b></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Purpose:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Compares the genomes of different organisms to understand evolutionary relationships, gene function, and genetic variation.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Techniques:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Involves aligning genomic sequences from different species to identify conserved and divergent regions.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:12.0pt"><span style="font-family:"Cambria","serif"">Medical Genomics</span></span></b></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Purpose:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Applies genomic information to diagnose, treat, and prevent diseases. It encompasses a range of practices including genetic testing, personalized medicine, and the study of genomic variations associated with diseases.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Techniques:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Includes whole-genome sequencing, exome sequencing, and genome-wide association studies (GWAS).</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:12.0pt"><span style="font-family:"Cambria","serif"">Population Genomics</span></span></b></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Purpose:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Studies genetic variations within and between populations to understand genetic diversity, adaptation, and disease susceptibility.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Techniques:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Includes large-scale genetic surveys, haplotype mapping, and studies of population genetics.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:12.0pt"><span style="font-family:"Cambria","serif"">Epigenomics</span></span></b></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Purpose:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Investigates the epigenetic modifications that affect gene expression without altering the DNA sequence itself. These modifications include DNA methylation and histone modification.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Techniques:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Includes bisulfite sequencing, chromatin immunoprecipitation sequencing (ChIP-seq), and RNA sequencing.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:12.0pt"><span style="font-family:"Cambria","serif"">Functional Annotation</span></span></b></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Purpose:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Involves assigning functions to genes and other genomic elements based on experimental data and computational predictions.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">Techniques:</span></span></b><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Utilizes databases, predictive algorithms, and functional assays to interpret genomic information.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:12.0pt"><span style="font-family:"Cambria","serif"">Research Methods</span></span></b></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">(1) <b>Sequencing Technologies:</b></span></span><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Advanced technologies such as next-generation sequencing (NGS) and third-generation sequencing provide comprehensive data on genome structure and variation.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">(2) <b>Bioinformatics:</b></span></span><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Involves using computational tools and software to analyze and interpret large-scale genomic data, including data from sequencing, expression profiling, and other genomic studies.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">(3) <b>Genetic Engineering:</b></span></span><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Techniques such as CRISPR-Cas9 enable targeted modifications of the genome to study gene function and develop new therapies.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><b><span lang="EN-US" style="font-size:12.0pt"><span style="font-family:"Cambria","serif"">Impact and Applications</span></span></b></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">(1) <b>Personalized Medicine:</b></span></span><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Genomics enables tailored medical treatments based on an individual’s genetic makeup, improving the effectiveness and safety of therapies.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">(2) <b>Disease Research:</b></span></span><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Provides insights into the genetic basis of diseases, leading to the identification of new biomarkers and therapeutic targets.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">(3) <b>Agricultural Genomics:</b></span></span><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Enhances crop and livestock breeding by identifying genes associated with desirable traits, such as disease resistance and yield improvement.</span></span></span></span></span></p> <p style="text-align:justify; margin-bottom:13px"><span style="font-size:11pt"><span style="line-height:normal"><span style="font-family:"Calibri","sans-serif""><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif"">(4) <b>Evolutionary Studies:</b></span></span><span lang="EN-US" style="font-size:10.0pt"><span style="font-family:"Cambria","serif""> Helps in understanding the genetic basis of evolution and the relationships between different species.</span></span></span></span></span></p> <p><span lang="EN-US" style="font-size:10.0pt"><span style="line-height:115%"><span style="font-family:"Cambria","serif""><a href="https://www.walshmedicalmedia.com/clinical-medical-sciences.html">Genomics </a>is a transformative field that continues to evolve rapidly, with significant implications for medicine, research, and biotechnology. 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