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.mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox vcard"><tbody><tr><th colspan="2" class="infobox-above" style="font-size: 100%;"><div class="honorific-prefix" style="font-weight: normal;"><a href="/wiki/Professor" title="Professor">Professor</a></div><div class="fn" style="font-size:125%;">Judith Clements</div><div class="honorific-suffix" style="font-weight: normal;"><span class="nobold noexcerpt nowraplinks" style="font-size:;"><span style="font-size: 100%;"><a href="/wiki/Companion_of_the_Order_of_Australia" class="mw-redirect" title="Companion of the Order of Australia">AC</a></span> <span style="font-size: 100%;"><a href="/wiki/Fellow_of_the_Australian_Academy_of_Health_and_Medical_Sciences" class="mw-redirect" title="Fellow of the Australian Academy of Health and Medical Sciences">FAHMS</a></span></span></div></th></tr><tr><th colspan="2" class="infobox-header" style="color: #202122; background:lavender">Personal details</th></tr><tr><th scope="row" class="infobox-label">Born</th><td class="infobox-data"><div style="display:inline" class="nickname">Judith Ann Clements</div><br /></td></tr><tr><th scope="row" class="infobox-label">Occupation</th><td class="infobox-data"><a href="/wiki/Medical_researcher" class="mw-redirect" title="Medical researcher">Medical researcher</a></td></tr><tr><td colspan="2" class="infobox-below" style="border-top: 1px solid right;"><div></div></td></tr></tbody></table> <p><b>Judith Ann Clements</b> is an Australian academic and educator, specializing in Kallikrein proteases in prostate and ovarian cancers. Clements is the scientific director at the Australian Prostate Cancer Research Centre – Queensland and was head of the Cancer Research Program at the Institute of Health and Biomedical Innovation (IHBI) of <a href="/wiki/Queensland_University_of_Technology" title="Queensland University of Technology">Queensland University of Technology</a> at the <a href="/wiki/Translational_Research_Institute_(Australia)" title="Translational Research Institute (Australia)">Translational Research Institute (Australia)</a> from 1997–2014.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Her biography was published in the Cancer and Metastasis Reviews in 2019<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Research">Research</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Judith_Clements&action=edit&section=1" title="Edit section: Research"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The Cancer Research Program led by Clements at QUT-IHBI, aims to more clearly understand the molecular and cellular basis for the development, progression, and metastasis of solid tumours.<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p><p>Clements has commented on her research, stating: </p> <dl><dd><i>"The primary interest of my group within the Hormone Dependent Cancer Program is the tissue kallikrein family of serine proteases. Our group was one of three worldwide that identified and characterised the expanded human tissue kallikrein gene locus on chromosome 19q13.4 in 1999. Since that time, our research has focused on defining the roles of particular kallikreins, and their variant forms, in hormone dependent cancers such as prostate, ovarian and endometrial cancer. We have used conventional/real time PCR and immunohistochemistry to determine the association of kallikrein expression with clinical disease to determine their usefulness as biomarkers for detection, prognostic outcome and therapeutic approaches. We are also utilizing over-expression and knockout systems to determine the effect of kallikrein expression in cancer cell lines at the cell biology level. Other studies in progress are directed to understanding the structure/function of the kallikreins, their substrate specificity and in vivo interacting proteins and genomic regulation. Other protease research interests are the type 2 trans membrane serine proteases (with Dr John Hooper) and the ADAMs (with Prof Adrian Herington and Dr Dimitri Odorico).</i><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></dd></dl> <div class="mw-heading mw-heading2"><h2 id="Education">Education</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Judith_Clements&action=edit&section=2" title="Edit section: Education"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Clements completed her <a href="/wiki/PhD" class="mw-redirect" title="PhD">PhD</a> in <a href="/wiki/Endocrinology" title="Endocrinology">Endocrinology</a> at <a href="/wiki/Monash_University" title="Monash University">Monash University</a> in 1989, her Master of Applied Science in 1983, after completing her Bachelor of Applied Science in 1982 and Diploma of Laboratory Technology in 1969 at the <a href="/wiki/Royal_Melbourne_Institute_of_Technology" title="Royal Melbourne Institute of Technology">Royal Melbourne Institute of Technology</a>.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Awards">Awards</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Judith_Clements&action=edit&section=3" title="Edit section: Awards"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>2019 QLD Greats Premier Medal <sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup></li> <li>2017 Fellow of the <a href="/wiki/Australian_Academy_of_Health_and_Medical_Sciences" title="Australian Academy of Health and Medical Sciences">Australian Academy of Health and Medical Sciences</a><sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup></li> <li>2015 Companion of the Order of Australia<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup></li> <li>2012 Women in Technology (WiT) Biotech Outstanding Achievement Award<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup></li> <li>2011 Queensland University of Technology Vice Chancellor's Award for Research Excellence<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup></li> <li>2007 Gold Medal, E.K.Frey–E.Werle Foundation for pioneering work in the Kallikrein field<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup></li> <li>2006 Research featured in "Ten Of The Best" National Health and Medical Research Council funded health and medical research successes<sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup></li> <li>2005 Alban Gee Prize, Urological Society of Australasia Annual Scientific Meeting</li> <li>2001 Queensland University of Technology Faculty of Science Distinguished Award for Excellence in Research</li> <li>2000 National Health and Medical Research Council Principal Research Fellowship</li> <li>2000 Silver Medal and Honorary Membership of the E.K.Frey–E.Werle Foundation (awarded at the International Conference, Kinin 2000, Munich)</li> <li>1998 Alban Gee Prize, Urological Society of Australasia Annual Scientific Meeting</li> <li>1995 National Health and Medical Research Council Senior Research Fellowship</li> <li>1991 Prize for an "Outstanding Presentation", Kinin 91, International Conference on Kallikreins and Kinins, Munich, Germany.<sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup></li></ul> <div class="mw-heading mw-heading2"><h2 id="Publications">Publications</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Judith_Clements&action=edit&section=4" title="Edit section: Publications"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>Zhao, Hong, Dong, Ying, Quan, Jingjing, Smith, Robert, Lam, Alfred, Weinstein, Stephen, Clements, Judith, Johnson, Newell W., and Gao, Jin (2011) <i>Correlation of the expression of human kallikrein-related peptidases 4 and 7 with the prognosis in oral squamous cell carcinoma.</i> Head and Neck, 33 (4). pp. 566-572.</li> <li>Gao, Jin, Collard, Rachael L., Bui, Loan, Herington, Adrian C., Nicol, David L., and Clements, Judith A. (2007) <i>Kallikrein 4 is a potential mediator of cellular interactions between cancer cells and osteoblasts in metastatic prostate cancer.</i> Prostate, 67 (4). pp. 348-360.</li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Judith_Clements&action=edit&section=5" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://staff.qut.edu.au/staff/clements">"Distinguished Professor Judith Clements profile"</a>. <i>staff.qut.edu.au</i>. Queensland University of Technology<span class="reference-accessdate">. Retrieved <span class="nowrap">7 August</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=staff.qut.edu.au&rft.atitle=Distinguished+Professor+Judith+Clements+profile&rft_id=http%3A%2F%2Fstaff.qut.edu.au%2Fstaff%2Fclements&rfr_id=info%3Asid%2Fen.wikipedia.org%3AJudith+Clements" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation journal cs1"><a rel="nofollow" class="external text" href="https://doi.org/10.1007/s10555-019-09809-1">"Biography—Judith Clements"</a>. <i>Cancer and Metastasis Reviews</i>. <b>38</b> (3): 329–329. 1 September 2019. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs10555-019-09809-1">10.1007/s10555-019-09809-1</a>. <a href="/wiki/ISSN_(identifier)" class="mw-redirect" title="ISSN (identifier)">ISSN</a> <a rel="nofollow" class="external text" href="https://search.worldcat.org/issn/1573-7233">1573-7233</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cancer+and+Metastasis+Reviews&rft.atitle=Biography%E2%80%94Judith+Clements&rft.volume=38&rft.issue=3&rft.pages=329-329&rft.date=2019-09-01&rft_id=info%3Adoi%2F10.1007%2Fs10555-019-09809-1&rft.issn=1573-7233&rft_id=https%3A%2F%2Fdoi.org%2F10.1007%2Fs10555-019-09809-1&rfr_id=info%3Asid%2Fen.wikipedia.org%3AJudith+Clements" class="Z3988"></span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://staff.qut.edu.au/staff/clements">"Distinguished Professor Judith Clements profile"</a>. <i>staff.qut.edu.au</i>. Queensland University of Technology<span class="reference-accessdate">. Retrieved <span class="nowrap">7 August</span> 2014</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=staff.qut.edu.au&rft.atitle=Distinguished+Professor+Judith+Clements+profile&rft_id=http%3A%2F%2Fstaff.qut.edu.au%2Fstaff%2Fclements&rfr_id=info%3Asid%2Fen.wikipedia.org%3AJudith+Clements" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.protease.net.au/index.php?id=23&pid=60">"Australian Protease Network – Professor Judith Clements"</a><span class="reference-accessdate">. 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Retrieved <span class="nowrap">6 January</span> 2015</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=australianprostatecentre.org&rft.atitle=Judith+Clements&rft_id=http%3A%2F%2Fwww.australianprostatecentre.org%2Fabout-us%2Four-people%2Fjudith-clements&rfr_id=info%3Asid%2Fen.wikipedia.org%3AJudith+Clements" class="Z3988"></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-6">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://statements.qld.gov.au/statements/87542">"Eight more Greats awarded on Queensland's 160th birthday"</a>. <i>Ministerial Media Statements</i><span class="reference-accessdate">. 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October 2017<span class="reference-accessdate">. Retrieved <span class="nowrap">8 December</span> 2020</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Australian+Academy+of+Health+and+Medical+Sciences&rft.atitle=AAHMS+Announces+its+Second+Scientific+Meeting+and+Induction+of+New+Fellows&rft.date=2017-10&rft_id=https%3A%2F%2Faahms.org%2Fwp-content%2Fuploads%2F2017%2F10%2F20171019-AAHMS-Media-Release_2017-New-Fellows-Announced1.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AJudith+Clements" class="Z3988"></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-8">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.qut.edu.au/institute-of-health-and-biomedical-innovation/about/news/news?news-id=90717">"Queen's Birthday honours"</a><span class="reference-accessdate">. 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Retrieved <span class="nowrap">6 January</span> 2015</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=wit.org.au&rft.atitle=WiT+Award+Winners+2012&rft_id=http%3A%2F%2Fwww.wit.org.au%2F2012-WiT-Award-Winners&rfr_id=info%3Asid%2Fen.wikipedia.org%3AJudith+Clements" class="Z3988"></span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-10">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.australianprostatecentre.org/about-us/our-people/judith-clements">"Judith Clements"</a>. <i>australianprostatecentre.org</i>. Australian Prostate Cancer Research Centre, Queensland<span class="reference-accessdate">. Retrieved <span class="nowrap">20 December</span> 2015</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=australianprostatecentre.org&rft.atitle=Judith+Clements&rft_id=http%3A%2F%2Fwww.australianprostatecentre.org%2Fabout-us%2Four-people%2Fjudith-clements&rfr_id=info%3Asid%2Fen.wikipedia.org%3AJudith+Clements" class="Z3988"></span></span> </li> <li id="cite_note-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-11">^</a></b></span> <span class="reference-text">Biol. Chem., Vol. 389, pp. 621–622, June 2008</span> </li> <li id="cite_note-12"><span class="mw-cite-backlink"><b><a href="#cite_ref-12">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.nhmrc.gov.au/guidelines/publications/r38">"10 of the Best 2006"</a>. <i>nhmrc.gov.au</i><span class="reference-accessdate">. Retrieved <span class="nowrap">6 January</span> 2015</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=nhmrc.gov.au&rft.atitle=10+of+the+Best+2006&rft_id=https%3A%2F%2Fwww.nhmrc.gov.au%2Fguidelines%2Fpublications%2Fr38&rfr_id=info%3Asid%2Fen.wikipedia.org%3AJudith+Clements" class="Z3988"></span></span> </li> <li id="cite_note-13"><span class="mw-cite-backlink"><b><a href="#cite_ref-13">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.australianprostatecentre.org/about-us/our-people/judith-clements">"Judith Clements"</a>. <i>australianprostatecentre.org</i>. Australian Prostate Cancer Research Centre, Queensland<span class="reference-accessdate">. Retrieved <span class="nowrap">20 December</span> 2015</span>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=australianprostatecentre.org&rft.atitle=Judith+Clements&rft_id=http%3A%2F%2Fwww.australianprostatecentre.org%2Fabout-us%2Four-people%2Fjudith-clements&rfr_id=info%3Asid%2Fen.wikipedia.org%3AJudith+Clements" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Judith_Clements&action=edit&section=6" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="http://www.aus-canprostatealliance.org/Members/j.clements-40qut.edu.au%7CAustralian-Canadian">Prostate Cancer Research Alliance</a></li> <li><a rel="nofollow" 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