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Sequencing</div><div class="subnav__links" data-ref="subnav-links"><a href="/applications/dna-sequencing" class="subnav__link" > DNA Sequencing </a><a href="/applications/rna-sequencing" class="subnav__link -is-active" > RNA Sequencing </a><a href="/applications/long-read-sequencing" class="subnav__link" > Long-Read Sequencing </a></div></div></nav><main class="main" role="main"><div class="hero"><div class="container"><div class="hero__row"><div class="hero__content"><ol class="breadcrumbs"><li><a href="/applications">Applications</a></li><li> RNA Sequencing </li></ol><script type="application/ld+json"> { "@context": "http://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Applications", "item": "https://www.elementbiosciences.com/applications" }, { "@type": "ListItem", "position": 2, "name": "RNA Sequencing" } ] } </script><h1 class="hero__heading"> RNA Sequencing </h1></div></div></div></div><div class="applications"><div class="container"><div class="applications__row"><div class="applications__column"><div class="applications-sidebar"><a href="/applications/dna-sequencing" class="applications-sidebar__link -heading" > DNA Sequencing </a><a href="/applications/dna-sequencing/whole-genome-sequencing" class="applications-sidebar__link" > Whole-Genome Sequencing </a><a href="/applications/dna-sequencing/targeted-sequencing" class="applications-sidebar__link" > Targeted Sequencing </a><a href="/applications/dna-sequencing/low-pass-wgs" class="applications-sidebar__link" > Low-Pass WGS </a><a href="/applications/dna-sequencing/methylation-sequencing" class="applications-sidebar__link" > Methylation Sequencing </a><a href="/applications/dna-sequencing/16s-amplicon-sequencing" class="applications-sidebar__link" > 16S Amplicon Sequencing </a><a href="/applications/rna-sequencing" class="applications-sidebar__link -heading" > RNA Sequencing </a><a href="/applications/rna-sequencing/single-cell-rna-sequencing" class="applications-sidebar__link" > Single-Cell RNA Sequencing </a><a href="/applications/rna-sequencing/microrna-sequencing" class="applications-sidebar__link" > MicroRNA Sequencing </a><a href="/applications/long-read-sequencing" class="applications-sidebar__link -heading" > Long-Read Sequencing </a></div></div><div class="applications__column"><div class="applications-blocks"><div class="applications-block applications-text"><div class="article"><p>RNA sequencing is a powerful tool for understanding the biological state of a cell or population of cells. Gene expression data can help scientists elucidate the downstream consequences of genomic variants or understand the impact of changes to the cellular environment. The Element AVITI System lends unique strengths to RNA sequencing experiments, including:<br /></p><ul><li>Negligible index hopping, preserving the integrity of multiplexed sample data.</li><li>Low optical duplication rates, increasing the effective coverage of samples at a given sequencing depth.</li><li>Throughput conveniently matched to the sequencing requirements of typical single-cell experimental designs.</li><li>Isoform identification with LoopSeq long-read technology.</li></ul></div></div><div class="applications-block applications-links"><div class="applications-links__group"><h3 class="applications-links__heading">Blog</h3><div class="applications-links__row"><a href="/blog/element-single-cell-rna-sequencing-affordable" class="resources-link" data-ref="resources-link"><div class="resources-link__preview" data-ref="resources-link-preview"><img src="https://www.elementbiosciences.com/uploads/blog/_resourcesPreview/elemBio-blog-purpleBubbles-102522.jpg" alt="Elem Bio blog purple Bubbles 102522" loading="lazy" ></div><div class="resources-link__photo"><img src="https://www.elementbiosciences.com/uploads/blog/_resourcesThumbnail/elemBio-blog-purpleBubbles-102522.jpg" alt="Elem Bio blog purple Bubbles 102522" loading="eager" ></div><div class="resources-link__content"><span class="resources-link__name">Count On Element Biosciences to Make Single-Cell RNA Sequencing More Affordable</span><div class="resources-link__meta"><span class="resources-link__date">Oct 25, 2022</span><span class="resources-link__size"></span></div></div><span class="resources-link__action">Read</span></a></div></div><div class="applications-links__group"><h3 class="applications-links__heading">Resources</h3><div class="applications-links__row"><a href="/resources/highly-accurate-and-reproducible-rnaseq-with-watchmaker-library-prep-on-the-aviti-system" class="resources-link -watch" data-ref="resources-link"><div class="resources-link__preview" data-ref="resources-link-preview"><img 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data-ref="resources-link" download><div class="resources-link__preview" data-ref="resources-link-preview"><img src="https://www.elementbiosciences.com/uploads/resources/thumbnails/_resourcesPreview/7281918/Watchmaker-poster.jpg" alt="Watchmaker poster" loading="lazy" ></div><div class="resources-link__photo"><img src="https://www.elementbiosciences.com/uploads/resources/thumbnails/_resourcesThumbnail/7281918/Watchmaker-poster.jpg" alt="Watchmaker poster" loading="eager" ></div><div class="resources-link__content"><span class="resources-link__name">Human Genome & RNA Sequencing with Watchmaker Genomics & Element AVITI™ System</span><div class="resources-link__meta"><span class="resources-link__date">Mar 10, 2022</span><span class="resources-link__size">922 KB</span></div></div><span class="resources-link__action">Download</span></a><a href="/resources/aviti-2x75-sequencing-kit-1b-reads-per-flow-cell" class="resources-link -watch" data-ref="resources-link"><div 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