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cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-menu mw-ui-icon-wikimedia-menu"></span> <span class="vector-dropdown-label-text">メインメニュー</span> </label> <div class="vector-dropdown-content"> <div id="vector-main-menu-unpinned-container" class="vector-unpinned-container"> <div id="vector-main-menu" class="vector-main-menu vector-pinnable-element"> <div class="vector-pinnable-header vector-main-menu-pinnable-header vector-pinnable-header-unpinned" data-feature-name="main-menu-pinned" data-pinnable-element-id="vector-main-menu" data-pinned-container-id="vector-main-menu-pinned-container" data-unpinned-container-id="vector-main-menu-unpinned-container" > <div class="vector-pinnable-header-label">メインメニュー</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-main-menu.pin">サイドバーに移動</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" 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title="最近新規に作成されたページの一覧"><span>新しいページ</span></a></li><li id="n-recentchanges" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E6%9C%80%E8%BF%91%E3%81%AE%E6%9B%B4%E6%96%B0" title="このウィキにおける最近の更新の一覧 [r]" accesskey="r"><span>最近の更新</span></a></li><li id="n-randompage" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E3%81%8A%E3%81%BE%E3%81%8B%E3%81%9B%E8%A1%A8%E7%A4%BA" title="無作為に選択されたページを読み込む [x]" accesskey="x"><span>おまかせ表示</span></a></li><li id="n-sandbox" class="mw-list-item"><a href="/wiki/Wikipedia:%E3%82%B5%E3%83%B3%E3%83%89%E3%83%9C%E3%83%83%E3%82%AF%E3%82%B9" title="練習用のページ"><span>練習用ページ</span></a></li><li id="n-commonsupload" class="mw-list-item"><a href="//commons.wikimedia.org/wiki/Special:UploadWizard?uselang=ja" title="画像やメディアファイルをウィキメディア・コモンズにアップロード"><span>アップロード (ウィキメディア・コモンズ)</span></a></li> </ul> </div> </div> <div id="p-help" class="vector-menu mw-portlet mw-portlet-help" > <div class="vector-menu-heading"> ヘルプ </div> <div class="vector-menu-content"> <ul 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id="p-vector-user-menu-preferences" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-userpage" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <nav class="vector-appearance-landmark" aria-label="表示"> <div id="vector-appearance-dropdown" class="vector-dropdown " title="ページのフォントサイズ、幅、色の外観を変更する" > <input type="checkbox" id="vector-appearance-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-appearance-dropdown" class="vector-dropdown-checkbox " aria-label="表示" > <label id="vector-appearance-dropdown-label" for="vector-appearance-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon 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user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%82%A2%E3%82%AB%E3%82%A6%E3%83%B3%E3%83%88%E4%BD%9C%E6%88%90&returnto=%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3" title="アカウントを作成してログインすることをお勧めしますが、必須ではありません" class=""><span>アカウント作成</span></a> </li> <li id="pt-login-2" class="user-links-collapsible-item mw-list-item user-links-collapsible-item"><a data-mw="interface" href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%83%AD%E3%82%B0%E3%82%A4%E3%83%B3&returnto=%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3" title="ログインすることを推奨します。ただし、必須ではありません。 [o]" accesskey="o" class=""><span>ログイン</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="その他の操作" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="個人用ツール" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">個人用ツール</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="利用者メニュー" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_ja.wikipedia.org&uselang=ja"><span>寄付</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%82%A2%E3%82%AB%E3%82%A6%E3%83%B3%E3%83%88%E4%BD%9C%E6%88%90&returnto=%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3" title="アカウントを作成してログインすることをお勧めしますが、必須ではありません"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>アカウント作成</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%83%AD%E3%82%B0%E3%82%A4%E3%83%B3&returnto=%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3" title="ログインすることを推奨します。ただし、必須ではありません。 [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>ログイン</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> ログアウトした編集者のページ <a href="/wiki/Wikipedia:%E3%82%A6%E3%82%A3%E3%82%AD%E3%83%9A%E3%83%87%E3%82%A3%E3%82%A2%E3%81%B8%E3%82%88%E3%81%86%E3%81%93%E3%81%9D" aria-label="編集の詳細"><span>もっと詳しく</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E8%87%AA%E5%88%86%E3%81%AE%E6%8A%95%E7%A8%BF%E8%A8%98%E9%8C%B2" title="このIPアドレスからなされた編集の一覧 [y]" accesskey="y"><span>投稿記録</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E3%83%88%E3%83%BC%E3%82%AF%E3%83%9A%E3%83%BC%E3%82%B8" title="このIPアドレスからなされた編集についての議論 [n]" accesskey="n"><span>トーク</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="サイト"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="目次" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">目次</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">サイドバーに移動</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">非表示</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">ページ先頭</div> </a> </li> <li id="toc-構造" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#構造"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>構造</span> </div> </a> <ul id="toc-構造-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-生産と機能" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#生産と機能"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>生産と機能</span> </div> </a> <ul id="toc-生産と機能-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-医学的な意義" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#医学的な意義"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>医学的な意義</span> </div> </a> <ul id="toc-医学的な意義-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-脚注" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#脚注"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>脚注</span> </div> </a> <ul id="toc-脚注-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-関連項目" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#関連項目"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>関連項目</span> </div> </a> <ul id="toc-関連項目-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-外部リンク" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#外部リンク"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>外部リンク</span> </div> </a> <ul id="toc-外部リンク-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="目次" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="目次の表示・非表示を切り替え" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">目次の表示・非表示を切り替え</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">ヒドロキシプロリン</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="特定の記事の別の言語版に移動します。利用可能な言語21件" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-21" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">21の言語版</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D9%87%DB%8C%D8%AF%D8%B1%D9%88%DA%A9%D8%B3%DB%8C%E2%80%8C%D9%BE%D8%B1%D9%88%D9%84%DB%8C%D9%86" title="South Azerbaijani: هیدروکسی‌پرولین" lang="azb" hreflang="azb" data-title="هیدروکسی‌پرولین" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Hidroxiprolina" title="カタロニア語: Hidroxiprolina" lang="ca" hreflang="ca" data-title="Hidroxiprolina" data-language-autonym="Català" data-language-local-name="カタロニア語" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Hydroxyprolin" title="ドイツ語: Hydroxyprolin" lang="de" hreflang="de" data-title="Hydroxyprolin" data-language-autonym="Deutsch" data-language-local-name="ドイツ語" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%A5%CE%B4%CF%81%CE%BF%CE%BE%CF%85%CF%80%CF%81%CE%BF%CE%BB%CE%AF%CE%BD%CE%B7" title="ギリシャ語: Υδροξυπρολίνη" lang="el" hreflang="el" data-title="Υδροξυπρολίνη" data-language-autonym="Ελληνικά" data-language-local-name="ギリシャ語" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Hydroxyproline" title="英語: Hydroxyproline" lang="en" hreflang="en" data-title="Hydroxyproline" data-language-autonym="English" data-language-local-name="英語" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Hidroxiprolina" title="スペイン語: Hidroxiprolina" lang="es" hreflang="es" data-title="Hidroxiprolina" data-language-autonym="Español" data-language-local-name="スペイン語" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%87%DB%8C%D8%AF%D8%B1%D9%88%DA%A9%D8%B3%DB%8C%E2%80%8C%D9%BE%D8%B1%D9%88%D9%84%DB%8C%D9%86" title="ペルシア語: هیدروکسی‌پرولین" lang="fa" hreflang="fa" data-title="هیدروکسی‌پرولین" data-language-autonym="فارسی" data-language-local-name="ペルシア語" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi badge-Q17559452 badge-recommendedarticle mw-list-item" title="おすすめ記事"><a href="https://fi.wikipedia.org/wiki/Hydroksiproliini" title="フィンランド語: Hydroksiproliini" lang="fi" hreflang="fi" data-title="Hydroksiproliini" data-language-autonym="Suomi" data-language-local-name="フィンランド語" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Hydroxyproline" title="フランス語: Hydroxyproline" lang="fr" hreflang="fr" data-title="Hydroxyproline" data-language-autonym="Français" data-language-local-name="フランス語" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Hidroxiprolina" title="ガリシア語: Hidroxiprolina" lang="gl" hreflang="gl" data-title="Hidroxiprolina" data-language-autonym="Galego" data-language-local-name="ガリシア語" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%B9%E0%A4%BE%E0%A4%87%E0%A4%A1%E0%A5%8D%E0%A4%B0%E0%A5%89%E0%A4%95%E0%A5%8D%E0%A4%B8%E0%A4%BF%E0%A4%AA%E0%A5%8D%E0%A4%B0%E0%A5%8B%E0%A4%B2%E0%A4%BF%E0%A4%A8" title="ヒンディー語: हाइड्रॉक्सिप्रोलिन" lang="hi" hreflang="hi" data-title="हाइड्रॉक्सिप्रोलिन" data-language-autonym="हिन्दी" data-language-local-name="ヒンディー語" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Idrossiprolina" title="イタリア語: Idrossiprolina" lang="it" hreflang="it" data-title="Idrossiprolina" data-language-autonym="Italiano" data-language-local-name="イタリア語" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%ED%95%98%EC%9D%B4%EB%93%9C%EB%A1%9D%EC%8B%9C%ED%94%84%EB%A1%A4%EB%A6%B0" title="韓国語: 하이드록시프롤린" lang="ko" hreflang="ko" data-title="하이드록시프롤린" data-language-autonym="한국어" data-language-local-name="韓国語" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Hydroxyproline" title="オランダ語: Hydroxyproline" lang="nl" hreflang="nl" data-title="Hydroxyproline" data-language-autonym="Nederlands" data-language-local-name="オランダ語" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Hydroksyprolina" title="ポーランド語: Hydroksyprolina" lang="pl" hreflang="pl" data-title="Hydroksyprolina" data-language-autonym="Polski" data-language-local-name="ポーランド語" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Hidroxiprolina" title="ポルトガル語: Hidroxiprolina" lang="pt" hreflang="pt" data-title="Hidroxiprolina" data-language-autonym="Português" data-language-local-name="ポルトガル語" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%93%D0%B8%D0%B4%D1%80%D0%BE%D0%BA%D1%81%D0%B8%D0%BF%D1%80%D0%BE%D0%BB%D0%B8%D0%BD" title="ロシア語: Гидроксипролин" lang="ru" hreflang="ru" data-title="Гидроксипролин" data-language-autonym="Русский" data-language-local-name="ロシア語" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Hidroksiprolin" title="セルボ・クロアチア語: Hidroksiprolin" lang="sh" hreflang="sh" data-title="Hidroksiprolin" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="セルボ・クロアチア語" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Hidroksiprolin" title="セルビア語: Hidroksiprolin" lang="sr" hreflang="sr" data-title="Hidroksiprolin" data-language-autonym="Српски / srpski" data-language-local-name="セルビア語" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%93%D1%96%D0%B4%D1%80%D0%BE%D0%BA%D1%81%D0%B8%D0%BF%D1%80%D0%BE%D0%BB%D1%96%D0%BD" title="ウクライナ語: Гідроксипролін" lang="uk" hreflang="uk" data-title="Гідроксипролін" data-language-autonym="Українська" data-language-local-name="ウクライナ語" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E7%BE%9F%E8%84%AF%E8%83%BA%E9%85%B8" title="中国語: 羟脯胺酸" lang="zh" hreflang="zh" data-title="羟脯胺酸" data-language-autonym="中文" data-language-local-name="中国語" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q12460151#sitelinks-wikipedia" title="言語間リンクを編集" class="wbc-editpage">リンクを編集</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="名前空間"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3" title="本文を閲覧 [c]" accesskey="c"><span>ページ</span></a></li><li id="ca-talk" class="new vector-tab-noicon mw-list-item"><a href="/w/index.php?title=%E3%83%8E%E3%83%BC%E3%83%88:%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3&action=edit&redlink=1" rel="discussion" class="new" title="「本文ページについての議論」 (存在しないページ) [t]" accesskey="t"><span>ノート</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="別の言語に切り替える" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">日本語</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav 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</div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="ページツール"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="表示"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">表示</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">サイドバーに移動</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">非表示</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">出典: フリー百科事典『ウィキペディア（Wikipedia）』</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="ja" dir="ltr"><table class="infobox bordered" style="width: 250px; font-size: 85%;"> <tbody><tr> <th colspan="2" style="background-color: #d6e0dc; text-align: center; font-size: 118%">ヒドロキシプロリン </th></tr> <tr> <td align="center" colspan="2" bgcolor="#ffffff"><span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:(2S,4R)-4-Hydroxyprolin.svg" class="mw-file-description" title="(2S,4R)-4-Hydroxyprolin.svg"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/c/c7/%282S%2C4R%29-4-Hydroxyprolin.svg/200px-%282S%2C4R%29-4-Hydroxyprolin.svg.png" decoding="async" width="200" height="110" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/c7/%282S%2C4R%29-4-Hydroxyprolin.svg/300px-%282S%2C4R%29-4-Hydroxyprolin.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/c/c7/%282S%2C4R%29-4-Hydroxyprolin.svg/400px-%282S%2C4R%29-4-Hydroxyprolin.svg.png 2x" data-file-width="219" data-file-height="120" /></a></span> </td></tr> <tr> <td align="center" colspan="2"><div class="NavFrame" style="border:none; padding:0;"><div class="NavHead" style="width:96%; background:transparent;text-align:center;"><a href="/wiki/IUPAC%E5%91%BD%E5%90%8D%E6%B3%95" title="IUPAC命名法">IUPAC名</a></div><div class="NavContent" style="width:96%; background:transparent;text-align:center;"><p style="word-wrap: break-word;">(2<i>S</i>,4<i>R</i>)-4-Hydroxypyrrolidine-2-carboxylic acid</p></div></div> </td></tr> <tr> <th style="background: #d6e0dc; text-align: center;" colspan="2">識別情報 </th></tr> <tr> <td><span style="white-space:nowrap;"><a href="/wiki/CAS%E7%99%BB%E9%8C%B2%E7%95%AA%E5%8F%B7" title="CAS登録番号">CAS登録番号</a></span> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?ref=51-35-4">51-35-4</a></span><sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Antu_mail-mark-notjunk.svg" class="mw-file-description" title="チェック"><img alt="チェック" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/7px-Antu_mail-mark-notjunk.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/11px-Antu_mail-mark-notjunk.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/14px-Antu_mail-mark-notjunk.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup> </td></tr> <tr> <td><a href="/wiki/PubChem" title="PubChem">PubChem</a> </td> <td><span title="pubchem.ncbi.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/5810">5810</a></span> </td></tr> <tr> <td><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a> </td> <td><span title="www.chemspider.com"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.5605.html">5605</a></span><sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Cross_reject.svg" class="mw-file-description" title="×"><img alt="×" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/57/Cross_reject.svg/7px-Cross_reject.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/57/Cross_reject.svg/11px-Cross_reject.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/57/Cross_reject.svg/14px-Cross_reject.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup> </td></tr> <tr> <td><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/RMB44WO89X">RMB44WO89X</a></span><sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Antu_mail-mark-notjunk.svg" class="mw-file-description" title="チェック"><img alt="チェック" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/7px-Antu_mail-mark-notjunk.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/11px-Antu_mail-mark-notjunk.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/14px-Antu_mail-mark-notjunk.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup> </td></tr> <tr> <td><a href="/wiki/MeSH" title="MeSH">MeSH</a> </td> <td><span title="meshb.nlm.nih.gov"><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/search?searchMethod=FullWord&searchInField=allTerms&sort=&size=20&searchType=exactMatch&from=0&q=Hydroxyproline">Hydroxyproline</a></span> </td></tr> <tr> <td colspan="2"><div class="NavFrame collapsed" style="border: none; padding: 0;"> <div class="NavHead" style="font-size: 105%; background: transparent; text-align: left; text-align:center; font-weight:bold; background:transparent;"><a href="/wiki/SMILES%E8%A8%98%E6%B3%95" title="SMILES記法">SMILES</a></div> <ul class="NavContent" style="list-style: none none; margin-left: 0; text-align:left;word-break:break-all; font-size: 105%; margin-top: 0; margin-bottom: 0; line-height: inherit;"><li style="line-height: inherit; margin: 0"><div style="border-top:1px solid #ccc; padding:0.4em 0.2em 0.2em 0.2em; word-wrap:break-word; text-indent:0em; text-align:left; font-size:11px; line-height:120%;">C1[C@H](CN[C@@H]1C(=O)O)O</div></li></ul> </div> </td></tr> <tr> <td colspan="2"><div class="NavFrame collapsed" style="border: none; padding: 0;"> <div class="NavHead" style="font-size: 105%; background: transparent; text-align: left; text-align:center; font-weight:bold; background:transparent;"><a href="/wiki/%E5%9B%BD%E9%9A%9B%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B3%AA%E8%AD%98%E5%88%A5%E5%AD%90" class="mw-redirect" title="国際化学物質識別子">InChI</a></div> <ul class="NavContent" style="list-style: none none; margin-left: 0; text-align:left;word-break:break-all; font-size: 105%; margin-top: 0; margin-bottom: 0; line-height: inherit;"><li style="line-height: inherit; margin: 0"><div style="border-top:1px solid #ccc; padding:0.2em 0 0.2em 1.5em; text-align:left;"><div style="word-wrap:break-word; text-indent:-1.5em; font-size:11px; line-height:120%;">InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1<sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Cross_reject.svg" class="mw-file-description" title="×"><img alt="×" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/57/Cross_reject.svg/7px-Cross_reject.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/57/Cross_reject.svg/11px-Cross_reject.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/57/Cross_reject.svg/14px-Cross_reject.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup></div><div style="word-wrap:break-word; text-indent:-1.5em; font-size:11px; line-height:120%;">Key: PMMYEEVYMWASQN-DMTCNVIQSA-N<sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Cross_reject.svg" class="mw-file-description" title="×"><img alt="×" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/57/Cross_reject.svg/7px-Cross_reject.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/57/Cross_reject.svg/11px-Cross_reject.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/57/Cross_reject.svg/14px-Cross_reject.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup></div></div></li><li style="line-height: inherit; margin: 0"><div style="border-top:1px solid #ccc; padding:0.2em 0 0.2em 1.5em; text-align:left;"><div style="word-wrap:break-word; text-indent:-1.5em; font-size:11px; line-height:120%;">InChI=1/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1</div><div style="word-wrap:break-word; text-indent:-1.5em; font-size:11px; line-height:120%;">Key: PMMYEEVYMWASQN-DMTCNVIQBF</div></div></li></ul> </div> </td></tr> <tr> <th colspan="2" style="background-color: #d6e0dc; text-align: center;">特性 </th></tr> <tr> <td><a href="/wiki/%E5%8C%96%E5%AD%A6%E5%BC%8F" title="化学式">化学式</a> </td> <td>C<sub>5</sub>H<sub>9</sub>NO<sub>3</sub> </td></tr> <tr> <td><a href="/wiki/%E3%83%A2%E3%83%AB%E8%B3%AA%E9%87%8F" title="モル質量">モル質量</a> </td> <td>131.13 g mol<sup>−1</sup> </td></tr> <tr> <td colspan="2" style="background-color: #d6e0dc; text-align: center; font-size: 80%;">特記なき場合、データは<a href="/wiki/%E5%B8%B8%E6%B8%A9" title="常温">常温</a> (25 <span lang="en">°C</span>)・<a href="/wiki/%E5%B8%B8%E5%9C%A7" class="mw-redirect" title="常圧">常圧</a> (100 kPa) におけるものである。 </td></tr></tbody></table> <p><b><small>L</small>-ヒドロキシプロリン</b>（<a href="/wiki/%E8%8B%B1%E8%AA%9E" title="英語">英語</a>: <span lang="en"><small>L</small>-hydroxyproline</span>）または、<b>(2<i>S</i>,4<i>R</i>)-4-ヒドロキシプロリン</b>（<a href="/wiki/%E8%8B%B1%E8%AA%9E" title="英語">英語</a>: <span lang="en">(2<i>S</i>,4<i>R</i>)-4-Hydroxyproline</span>）は、天然に存在する二級環状アミノ酸（かつては<a href="/wiki/%E3%82%A4%E3%83%9F%E3%83%8E%E9%85%B8" title="イミノ酸">イミノ酸</a>とも呼ばれた）の一種である。<a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B3%AA%E6%A7%8B%E9%80%A0%E3%83%87%E3%83%BC%E3%82%BF%E3%83%90%E3%83%B3%E3%82%AF" title="蛋白質構造データバンク">蛋白質構造データバンク</a>による略称は <b>Hyp</b> または <b>O</b> 。 </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="構造"><span id=".E6.A7.8B.E9.80.A0"></span>構造</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3&action=edit&section=1" title="節を編集: 構造"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>ヒドロキシプロリンは、<a href="/wiki/%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3" title="プロリン">プロリン</a>のγ<a href="/wiki/%E7%82%AD%E7%B4%A0" title="炭素">炭素</a>原子に<a href="/wiki/%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E5%9F%BA" title="ヒドロキシ基">ヒドロキシ基</a>が結合した構造をしている。 </p><p>また<a href="/wiki/%E7%8F%AA%E8%97%BB" title="珪藻">珪藻</a>の<a href="/wiki/%E7%B4%B0%E8%83%9E%E5%A3%81" title="細胞壁">細胞壁</a>にあり、<a href="/wiki/%E3%82%B1%E3%82%A4%E7%B4%A0" title="ケイ素">ケイ素</a>の堆積に必要な2,3-シス-3, 4-トランス-ジヒドロキシプロリンのように、別の形のヒドロキシプロリンも天然に存在する。<a href="/wiki/%E5%8E%9F%E7%94%9F%E7%94%9F%E7%89%A9" title="原生生物">原生生物</a>である<a href="/wiki/%E5%8D%B5%E8%8F%8C" title="卵菌">卵菌</a>にもヒドロキシプロリンが見られる<sup id="cite_ref-Alexopoulos_1996_1-0" class="reference"><a href="#cite_note-Alexopoulos_1996-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>。 </p> <div class="mw-heading mw-heading2"><h2 id="生産と機能"><span id=".E7.94.9F.E7.94.A3.E3.81.A8.E6.A9.9F.E8.83.BD"></span>生産と機能</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3&action=edit&section=2" title="節を編集: 生産と機能"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>ヒドロキシプロリンは<a href="/wiki/%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E8%B3%AA%E5%90%88%E6%88%90" class="mw-redirect" title="タンパク質合成">タンパク質合成</a>後の<a href="/wiki/%E7%BF%BB%E8%A8%B3%E5%BE%8C%E4%BF%AE%E9%A3%BE" title="翻訳後修飾">翻訳後修飾</a>として、<a href="/wiki/%E3%83%97%E3%83%AD%E3%83%AA%E3%83%AB%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%A9%E3%83%BC%E3%82%BC" class="mw-redirect" title="プロリルヒドロキシラーゼ">プロリルヒドロキシラーゼ</a>によってプロリンに<a href="/wiki/%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%AB%E5%9F%BA" class="mw-redirect" title="ヒドロキシル基">ヒドロキシル基</a>が導入されることにより生成される。 </p><p>ヒドロキシプロリンは<a href="/wiki/%E3%82%B3%E3%83%A9%E3%83%BC%E3%82%B2%E3%83%B3" title="コラーゲン">コラーゲン</a>の主要な成分であり、プロリンとともにコラーゲンの安定性を担っている<sup id="cite_ref-Nelson_2-0" class="reference"><a href="#cite_note-Nelson-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup>。これらは、コラーゲンの<a href="/wiki/%E8%9E%BA%E6%97%8B" title="螺旋">らせん</a>をきつく巻くことを可能にし<sup id="cite_ref-Brinckmann_3-0" class="reference"><a href="#cite_note-Brinckmann-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup>、また<a href="/wiki/%E6%B0%B4%E7%B4%A0%E7%B5%90%E5%90%88" title="水素結合">水素結合</a>を作ることで、コラーゲンの三本鎖らせんを安定化している。コラーゲン以外には滅多に見られないが、<a href="/wiki/%E5%93%BA%E4%B9%B3%E9%A1%9E" title="哺乳類">哺乳類</a>の持つタンパク質で他に唯一含まれているのは<a href="/wiki/%E3%82%A8%E3%83%A9%E3%82%B9%E3%83%81%E3%83%B3" title="エラスチン">エラスチン</a>である<sup id="cite_ref-Ward_4-0" class="reference"><a href="#cite_note-Ward-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup>。このため、ヒドロキシプロリンはコラーゲンや<a href="/wiki/%E3%82%BC%E3%83%A9%E3%83%81%E3%83%B3" title="ゼラチン">ゼラチン</a>の量を測定する指標となりうる。 </p> <div class="mw-heading mw-heading2"><h2 id="医学的な意義"><span id=".E5.8C.BB.E5.AD.A6.E7.9A.84.E3.81.AA.E6.84.8F.E7.BE.A9"></span>医学的な意義</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3&action=edit&section=3" title="節を編集: 医学的な意義"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>プロリンのヒドロキシル化には<a href="/wiki/%E3%82%A2%E3%82%B9%E3%82%B3%E3%83%AB%E3%83%93%E3%83%B3%E9%85%B8" title="アスコルビン酸">アスコルビン酸</a>（<a href="/wiki/%E3%83%93%E3%82%BF%E3%83%9F%E3%83%B3C" title="ビタミンC">ビタミンC</a>）が必要である。そのためビタミンCが不足するとコラーゲン中のヒドロキシプロリンの割合が少なくなって安定性が低下し、<a href="/wiki/%E5%A3%8A%E8%A1%80%E7%97%85" title="壊血病">壊血病</a>を引き起こす。 </p> <div class="mw-heading mw-heading2"><h2 id="脚注"><span id=".E8.84.9A.E6.B3.A8"></span>脚注</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3&action=edit&section=4" title="節を編集: 脚注"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <ol class="references"> <li id="cite_note-Alexopoulos_1996-1"><b><a href="#cite_ref-Alexopoulos_1996_1-0">^</a></b> <span class="reference-text">Alexopoulos, C. J., C. W. Mims, & M. Blackwell. 1996. <i>Introductory Mycology</i>, 4th ed., p. 687-688. (New York: John Wiley & Sons). <a href="/wiki/%E7%89%B9%E5%88%A5:%E6%96%87%E7%8C%AE%E8%B3%87%E6%96%99/0471522295" class="internal mw-magiclink-isbn">ISBN 0-471-52229-5</a>.</span> </li> <li id="cite_note-Nelson-2"><b><a href="#cite_ref-Nelson_2-0">^</a></b> <span class="reference-text">Nelson, D. L. and Cox, M. M. (2005) Lehninger's Principles of Biochemistry, 4th Edition, W. H. Freeman and Company, New York.</span> </li> <li id="cite_note-Brinckmann-3"><b><a href="#cite_ref-Brinckmann_3-0">^</a></b> <span class="reference-text">Brinckmann, J., Notbohm, H. and Müller, P. K. (2005) Collagen, Topics in Current Chemistry 247, Springer, Berlin.</span> </li> <li id="cite_note-Ward-4"><b><a href="#cite_ref-Ward_4-0">^</a></b> <span class="reference-text">Ward, A. G. and Courts, A. (1977) The Science and Technology of Gelatin, Academic Press, New York.</span> </li> </ol> <div class="mw-heading mw-heading2"><h2 id="関連項目"><span id=".E9.96.A2.E9.80.A3.E9.A0.85.E7.9B.AE"></span>関連項目</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3&action=edit&section=5" title="節を編集: 関連項目"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/%E3%82%A4%E3%83%9F%E3%83%8E%E9%85%B8" title="イミノ酸">イミノ酸</a></li> <li><a href="/wiki/%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%AA%E3%82%B7%E3%83%B3" title="ヒドロキシリシン">ヒドロキシリシン</a></li> <li><a href="/wiki/%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%AB%E5%8C%96%E5%8F%8D%E5%BF%9C" class="mw-redirect" title="ヒドロキシル化反応">ヒドロキシル化反応</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="外部リンク"><span id=".E5.A4.96.E9.83.A8.E3.83.AA.E3.83.B3.E3.82.AF"></span>外部リンク</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7%E3%83%97%E3%83%AD%E3%83%AA%E3%83%B3&action=edit&section=6" title="節を編集: 外部リンク"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://www.nibiohn.go.jp/eiken/info/hf2.html">ヒドロキシリシン (別名：ヒドロキシリジン)</a> - 素材情報データベース＜有効性情報＞（<a href="/wiki/%E5%9B%BD%E7%AB%8B%E5%81%A5%E5%BA%B7%E3%83%BB%E6%A0%84%E9%A4%8A%E7%A0%94%E7%A9%B6%E6%89%80" title="国立健康・栄養研究所">国立健康・栄養研究所</a>）</li> <li><a rel="nofollow" class="external text" href="https://www.nibiohn.go.jp/eiken/info/hf2.html">4-ヒドロキシプロリン</a> - 同</li> <li><a rel="nofollow" class="external text" href="http://data.cas-msds.com/Hydroxyproline.html">ヒドロキシプロリン研究データ</a></li></ul>    </div><noscript><img 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