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Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Henrique%20R.%20N.%20Aguiar"> Henrique R. N. Aguiar</a>, <a href="https://publications.waset.org/abstracts/search?q=Ralph%20Smith"> Ralph Smith</a>, <a href="https://publications.waset.org/abstracts/search?q=James%20Baldock"> James Baldock</a>, <a href="https://publications.waset.org/abstracts/search?q=Sam%20Botchey"> Sam Botchey</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Femoral neck stress fractures (FNSF) are uncommon, making up 1 to 7.2% of stress fractures in healthy subjects. FNSFs are prevalent in young women, military recruits, endurance athletes, and individuals with energy deficiency syndrome or female athlete triad. Presentation is often non-specific and is often misdiagnosed following the initial examination. There is limited research addressing the return–to–activity time after FNSF. Previous studies have demonstrated prognostic time predictions based on various imaging techniques. Here, (1) OxSport clinic FNSF practice standards are retrospectively reviewed, (2) FNSF cohort demographics are examined, (3) Regression models were used to predict return–to–activity prognosis and consequently determine bone stress risk factors. Methods: Patients with a diagnosis of FNSF attending Oxsport clinic between 01/06/2020 and 01/01/2020 were selected from the Rheumatology Assessment Database Innovation in Oxford (RhADiOn) and OxSport Stress Fracture Database (n = 14). (1) Clinical practice was audited against five criteria based on local and National Institute for Health Care Excellence guidance, with a 100% standard. (2) Demographics of the FNSF cohort were examined with Student’s T-Test. (3) Lastly, linear regression and Random Forest regression models were used on this patient cohort to predict return–to–activity time. Consequently, an analysis of feature importance was conducted after fitting each model. Results: OxSport clinical practice met standard (100%) in 3/5 criteria. The criteria not met were patient waiting times and documentation of all bone stress risk factors. Importantly, analysis of patient demographics showed that of the population with complete bone stress risk factor assessments, 53% were positive for modifiable bone stress risk factors. Lastly, linear regression analysis was utilized to identify demographic factors that predicted return–to–activity time [R2 = 79.172%; average error 0.226]. This analysis identified four key variables that predicted return-to-activity time: vitamin D level, total hip DEXA T value, femoral neck DEXA T value, and history of an eating disorder/disordered eating. Furthermore, random forest regression models were employed for this task [R2 = 97.805%; average error 0.024]. Analysis of the importance of each feature again identified a set of 4 variables, 3 of which matched with the linear regression analysis (vitamin D level, total hip DEXA T value, and femoral neck DEXA T value) and the fourth: age. Conclusion: OxSport clinical practice could be improved by more comprehensively evaluating bone stress risk factors. The importance of this evaluation is demonstrated by the population found positive for these risk factors. Using this cohort, potential bone stress risk factors that significantly impacted return-to-activity prognosis were predicted using regression models. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=eating%20disorder" title="eating disorder">eating disorder</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20stress%20risk%20factor" title=" bone stress risk factor"> bone stress risk factor</a>, <a href="https://publications.waset.org/abstracts/search?q=femoral%20neck%20stress%20fracture" title=" femoral neck stress fracture"> femoral neck stress fracture</a>, <a href="https://publications.waset.org/abstracts/search?q=vitamin%20D" title=" vitamin D"> vitamin D</a> </p> <a href="https://publications.waset.org/abstracts/140591/management-of-femoral-neck-stress-fractures-at-a-specialist-centre-and-predictive-factors-to-return-to-activity-time-an-audit" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140591.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">186</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14537</span> Design Improvement of Dental Implant-Based on Bone Remodelling</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Solehuddin%20Shuib">Solehuddin Shuib</a>, <a href="https://publications.waset.org/abstracts/search?q=Koay%20Boon%20Aik"> Koay Boon Aik</a>, <a href="https://publications.waset.org/abstracts/search?q=Zainul%20Ahmad%20Rajion"> Zainul Ahmad Rajion</a> </p> <p class="card-text"><strong>Abstract:</strong></p> There are many types of mechanical failure on the dental implant. In this project, the failure that needs to take into consideration is the bone resorption on the dental implant. Human bone has its ability to remodel after the implantation. As the dental implant is installed into the bone, the bone will detect and change the bone structure to achieve new biomechanical environment. This phenomenon is known as bone remodeling. The objective of the project is to improve the performance of dental implant by using different types of design. These designs are used to analyze and predict the failure of the dental implant by using finite element analysis (FEA) namely ANSYS. The bone is assumed to be fully attached to the implant or cement. Hence, results are then compared with other researchers. The results were presented in the form of Von Mises stress, normal stress, shear stress analysis, and displacement. The selected design will be analyzed further based on a theoretical calculation of bone remodeling on the dental implant. The results have shown that the design constructed passed the failure analysis. Therefore, the selected design is proven to have a stable performance at the recovery stage. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dental%20implant" title="dental implant">dental implant</a>, <a href="https://publications.waset.org/abstracts/search?q=FEA" title=" FEA"> FEA</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20remodeling" title=" bone remodeling"> bone remodeling</a>, <a href="https://publications.waset.org/abstracts/search?q=design" title=" design"> design</a> </p> <a href="https://publications.waset.org/abstracts/19662/design-improvement-of-dental-implant-based-on-bone-remodelling" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19662.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">509</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14536</span> Effect of Aerobic Exercise on Estrogen Hormone and Bone Mineral Density in Osteoporotic Women</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Noha%20Mohamed%20Abdelhafez%20Dahy">Noha Mohamed Abdelhafez Dahy</a>, <a href="https://publications.waset.org/abstracts/search?q=Azza%20Abd%20El-Aziz"> Azza Abd El-Aziz</a>, <a href="https://publications.waset.org/abstracts/search?q=Eman%20Ahmed"> Eman Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Marwa%20El-Sayed"> Marwa El-Sayed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Osteoporosis is a metabolic bone disease characterized by low bone mass, deterioration of bone tissue, and disruption of bone microarchitecture, which leads to compromised bone strength and an increased risk of fracture, commonly it occurs in women 10-15 years after menopause, the mean age of menopause is 51 years. Menopause is natural physiological changes primary because of decline of ovaries function with age which leads to decrease of estrogen hormone production which is the main hormone for bone continuous remodeling for bone density maintenance. Exercise increase stimulation of bone growth to keep bone mass by the effect of the mechanical stimulation, antigravity loading and stress exerted on musculoskeletal muscles. Purpose: This study aimed to determine the effect of aerobic exercise on estrogen hormone and bone mineral density (BMD) in osteoporotic women and the correlation between the estrogen and BMD. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Osteoporosis" title="Osteoporosis">Osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=Postmenopause" title=" Postmenopause"> Postmenopause</a>, <a href="https://publications.waset.org/abstracts/search?q=Aerobic%20exercise" title=" Aerobic exercise"> Aerobic exercise</a>, <a href="https://publications.waset.org/abstracts/search?q=DEXA" title=" DEXA"> DEXA</a>, <a href="https://publications.waset.org/abstracts/search?q=Serum%20Estrogen" title=" Serum Estrogen"> Serum Estrogen</a> </p> <a href="https://publications.waset.org/abstracts/166825/effect-of-aerobic-exercise-on-estrogen-hormone-and-bone-mineral-density-in-osteoporotic-women" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166825.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">94</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14535</span> Viscoelastic Characterization of Bovine Trabecular Bone Samples</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20Ramirez%20D.%20Edgar">I. Ramirez D. Edgar</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Angeles%20H.%20Jos%C3%A9"> J. Angeles H. José</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruiz%20C.%20Osvaldo"> Ruiz C. Osvaldo</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Jacobo%20A.%20Victor"> H. Jacobo A. Victor</a>, <a href="https://publications.waset.org/abstracts/search?q=Ortiz%20P.%20Armando"> Ortiz P. Armando</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Knowledge of bone mechanical properties is important for bone substitutes design and fabrication, and more efficient prostheses development. The aim of this study is to characterize the viscoelastic behavior of bone specimens, through stress relaxation and fatigue tests performed to trabecular bone samples from bovine femoral heads. Relaxation tests consisted on preloading the samples at five different magnitudes and evaluate them for 1020 seconds, adjusting the results to a KWW mathematical model. Fatigue tests consisted of 700 load cycles and analyze their status at the end of the tests. As a conclusion we have that between relaxation stress and each preload there is linear relation and for samples with initial Young´s modulus greater than 1.5 GPa showed no effects due fatigue test loading cycles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20viscoelasticity" title="bone viscoelasticity">bone viscoelasticity</a>, <a href="https://publications.waset.org/abstracts/search?q=fatigue%20test" title=" fatigue test"> fatigue test</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20relaxation%20test" title=" stress relaxation test"> stress relaxation test</a>, <a href="https://publications.waset.org/abstracts/search?q=trabecular%20bone%20properties" title=" trabecular bone properties"> trabecular bone properties</a> </p> <a href="https://publications.waset.org/abstracts/21146/viscoelastic-characterization-of-bovine-trabecular-bone-samples" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21146.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">495</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14534</span> Fluoride-Induced Stress and Its Association with Bone Developmental Pathway in Osteosarcoma Cells</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Deepa%20Gandhi">Deepa Gandhi</a>, <a href="https://publications.waset.org/abstracts/search?q=Pravin%20K.%20Naoghare"> Pravin K. Naoghare</a>, <a href="https://publications.waset.org/abstracts/search?q=Amit%20Bafana"> Amit Bafana</a>, <a href="https://publications.waset.org/abstracts/search?q=Krishnamurthi%20Kannan"> Krishnamurthi Kannan</a>, <a href="https://publications.waset.org/abstracts/search?q=Saravanadevi%20Sivanesana"> Saravanadevi Sivanesana</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Oxidative stress is known to depreciate normal functioning of osteoblast cells. Present study reports oxidative/inflammatory signatures in fluoride exposed human osteosarcoma (HOS) cells and its possible association with the genes involved in bone developmental pathway. Microarray analysis was performed to understand the possible molecular mechanisms of stress-mediated bone lose in HOS cells. Cells were chronically exposed with sub-lethal concentration of fluoride. Global gene expression is profiling revealed 34 up regulated and 2598 down-regulated genes, which were associated with several biological processes including bone development, osteoblast differentiation, stress response, inflammatory response, apoptosis, regulation of cell proliferation. Microarray data were further validated through qRT-PCR and western blot analyses using key representative genes. Based on these findings, it can be proposed that chronic exposure of fluoride may impair bone development via oxidative and inflammatory stress. The present finding also provides important biological clues, which will be helpful for the development of therapeutic targets against diseases related bone. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone" title="bone">bone</a>, <a href="https://publications.waset.org/abstracts/search?q=HOS%20cells" title=" HOS cells"> HOS cells</a>, <a href="https://publications.waset.org/abstracts/search?q=microarray" title=" microarray"> microarray</a>, <a href="https://publications.waset.org/abstracts/search?q=stress" title=" stress"> stress</a> </p> <a href="https://publications.waset.org/abstracts/40877/fluoride-induced-stress-and-its-association-with-bone-developmental-pathway-in-osteosarcoma-cells" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/40877.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">383</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14533</span> Risk Association of RANKL and OPG Gene Polymorphism with Breast to Bone Metastasis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Najeeb%20Ullah%20Khan">Najeeb Ullah Khan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The receptor activator NF-κβ ligand (RANKL) and Osteoprotegerin (OPG) polymorphisms have been associated with the progression of breast cancer to bone metastasis. Here, we aimed to investigate the association of RANKL and OPG gene polymorphism with breast to bone metastasis in the Pashtun population, Pakistan. Methods: Genomic DNA was obtained from all the study subjects (106 breast cancer, 58 breast to bone metastasis, and 51 healthy controls). RANKL (rs9533156) and OPG (rs2073618, rs3102735) polymorphisms were genotyped using Tetra-ARMS PCR. Results: Our results indicated that the frequencies of OPG (rs3102735) risk allele and genotypes carrying risk allele in breast cancer vs healthy control (C- p=0.005; CC- p=0.0208; TC- p=0.0181), bone metastasis vs healthy control (C- p=0.0211; CC- p=0.0153; TC- p=0.0775), and breast cancer vs breast to bone metastasis (C- p=0.0001; CC- p=0.0001; TC- p=0.001) were found significantly associated with disease risk. However, there was no significant association observed for OPG (rs2073618) risk allele and risk allele containing genotypes in all study groups. Similarly, RANKL (rs9533156) risk alleles and corresponding genotypes in breast cancer vs healthy control (C- p=0.0001; CC- p=0.0001; TC- p=0.0084), bone metastasis vs healthy control (C- p=0.0001; CC- p=0.0001; TC- p=0.5593), and breast cancer vs breast to bone metastasis (C- p=0.0185; CC- p=0.6077; TC- p=0.1436) showed significant association except for the risk allele carrying genotypes in breast cancer to bone metastasis (TC, p=0.1436; CC, p=0.6077). Conclusion: OPG (rs3102735) and RANKL (rs9533156) showed significant association with breast to bone metastasis, while OPG (rs2073618) didn’t show a significant association with breast to bone metastasis in Pashtun population of Pakistan. However, more investigation will be required to disseminate the results while gene sequencing or whole-exome sequencing. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=breast%20cancer" title="breast cancer">breast cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20metastasis" title=" bone metastasis"> bone metastasis</a>, <a href="https://publications.waset.org/abstracts/search?q=OPG" title=" OPG"> OPG</a>, <a href="https://publications.waset.org/abstracts/search?q=RANKL" title=" RANKL"> RANKL</a>, <a href="https://publications.waset.org/abstracts/search?q=polymorphism" title=" polymorphism"> polymorphism</a> </p> <a href="https://publications.waset.org/abstracts/140839/risk-association-of-rankl-and-opg-gene-polymorphism-with-breast-to-bone-metastasis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140839.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">198</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14532</span> Stress-Strain Relation for Human Trabecular Bone Based on Nanoindentation Measurements</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marek%20Pawlikowski">Marek Pawlikowski</a>, <a href="https://publications.waset.org/abstracts/search?q=Krzysztof%20Jankowski"> Krzysztof Jankowski</a>, <a href="https://publications.waset.org/abstracts/search?q=Konstanty%20Skalski"> Konstanty Skalski</a>, <a href="https://publications.waset.org/abstracts/search?q=Anna%20Makuch"> Anna Makuch</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nanoindentation or depth-sensing indentation (DSI) technique has proven to be very useful to measure mechanical properties of various tissues at a micro-scale. Bone tissue, both trabecular and cortical one, is one of the most commonly tested tissues by means of DSI. Most often such tests on bone samples are carried out to compare the mechanical properties of lamellar and interlamellar bone, osteonal bone as well as compact and cancellous bone. In the paper, a relation between stress and strain for human trabecular bone is presented. The relation is based on the results of nanoindentation tests. The formulation of a constitutive model for human trabecular bone is based on nanoindentation tests. In the study, the approach proposed by Olivier-Pharr is adapted. The tests were carried out on samples of trabecular tissue extracted from human femoral heads. The heads were harvested during surgeries of artificial hip joint implantation. Before samples preparation, the heads were kept in 95% alcohol in temperature 4 Celsius degrees. The cubic samples cut out of the heads were stored in the same conditions. The dimensions of the specimens were 25 mm x 25 mm x 20 mm. The number of 20 samples have been tested. The age range of donors was between 56 and 83 years old. The tests were conducted with the indenter spherical tip of the diameter 0.200 mm. The maximum load was P = 500 mN and the loading rate 500 mN/min. The data obtained from the DSI tests allows one only to determine bone behoviour in terms of nanoindentation force vs. nanoindentation depth. However, it is more interesting and useful to know the characteristics of trabecular bone in the stress-strain domain. This allows one to simulate trabecular bone behaviour in a more realistic way. The stress-strain curves obtained in the study show relation between the age and the mechanical behaviour of trabecular bone. It was also observed that the bone matrix of trabecular tissue indicates an ability of energy absorption. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=constitutive%20model" title="constitutive model">constitutive model</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20behaviour" title=" mechanical behaviour"> mechanical behaviour</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoindentation" title=" nanoindentation"> nanoindentation</a>, <a href="https://publications.waset.org/abstracts/search?q=trabecular%20bone" title=" trabecular bone"> trabecular bone</a> </p> <a href="https://publications.waset.org/abstracts/74950/stress-strain-relation-for-human-trabecular-bone-based-on-nanoindentation-measurements" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74950.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">225</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14531</span> The Role of Lifetime Stress in the Relation between Socioeconomic Status and Health-Risk Behaviors</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Teresa%20Smith">Teresa Smith</a>, <a href="https://publications.waset.org/abstracts/search?q=Farrah%20Jacquez"> Farrah Jacquez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Health-risk behaviors (e.g., smoking, poor diet) directly increase the risk for chronic disease and morbidity. There is substantial evidence of a negative association between socioeconomic status (SES) and engagement in health-risk behaviors. However, due to the complexity of SES, researchers have suggested looking beyond this factor to fully understand the mechanisms that underlie engagement in health-risk behaviors. Stress is one plausible mechanism through which SES impacts health-risk behaviors. Currently, it remains unclear how stress occurring across the life course might impact health behaviors and explain the association between SES and these behaviors. To address the gaps in the literature, 172 adults between the ages of 18-49 were surveyed about their lifetime stress exposure, sociodemographic variables, and health-risk behaviors via an online recruitment portal, Prolific. Five major findings emerged from the current study. First, SES was negatively associated with engagement in health-risk behaviors and lifetime stress above and beyond current stress and other relevant demographics. Second, lifetime stress was significantly associated with health-risk behaviors above and beyond current stress and relevant demographic variables. Third, lifetime stress fully mediated the association between SES and health-risk behaviors above and beyond current stress and other demographics. Fourth, the severity of stress experienced emerged as the most significant lifetime stress variable that explains the relation between SES and health-risk behaviors. Fifth and finally, lower SES and experiencing financial and legal/crime stressors increased the likelihood of engaging in health-risk behaviors. The current study results align with previous research and suggest that stress occurring over the lifespan impacts the relation between SES and health-risk behaviors, which are in turn known to impact health outcomes. However, our findings move the current literature forward by providing a more nuanced understanding of the specific aspects of stress that influence this association. Specifically, the severity of stress experienced across the entire lifespan was the most important aspect of stress when examining the association between SES and health-risk behaviors. Further, individuals most at risk for engaging in health-risk behaviors are those of the lowest SES and experience financial and legal/crime stressors. These findings have the potential to inform interventions and policies aimed at addressing health-risk behaviors by providing a more sophisticated understanding of the impact of stress. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stress" title="stress">stress</a>, <a href="https://publications.waset.org/abstracts/search?q=health%20behaviors" title=" health behaviors"> health behaviors</a>, <a href="https://publications.waset.org/abstracts/search?q=socioeconomic%20status" title=" socioeconomic status"> socioeconomic status</a>, <a href="https://publications.waset.org/abstracts/search?q=health" title=" health"> health</a> </p> <a href="https://publications.waset.org/abstracts/133185/the-role-of-lifetime-stress-in-the-relation-between-socioeconomic-status-and-health-risk-behaviors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/133185.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">152</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14530</span> A Review on Bone Grafting, Artificial Bone Substitutes and Bone Tissue Engineering</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kasun%20Gayashan%20Samarawickrama">Kasun Gayashan Samarawickrama</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bone diseases, defects, and fractions are commonly seen in modern life. Since bone is regenerating dynamic living tissue, it will undergo healing process naturally, it cannot recover from major bone injuries, diseases and defects. In order to overcome them, bone grafting technique was introduced. Gold standard was the best method for bone grafting for the past decades. Due to limitations of gold standard, alternative methods have been implemented. Apart from them artificial bone substitutes and bone tissue engineering have become the emerging methods with technology for bone grafting. Many bone diseases and defects will be healed permanently with these promising techniques in future. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20grafting" title="bone grafting">bone grafting</a>, <a href="https://publications.waset.org/abstracts/search?q=gold%20standard" title=" gold standard"> gold standard</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20substitutes" title=" bone substitutes"> bone substitutes</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20tissue%20engineering" title=" bone tissue engineering"> bone tissue engineering</a> </p> <a href="https://publications.waset.org/abstracts/79771/a-review-on-bone-grafting-artificial-bone-substitutes-and-bone-tissue-engineering" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79771.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">306</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14529</span> Forced Swim Stress Does Not Induce Structural Chromosomal Aberrations in Rat Bone Marrow</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Y.%20Alfaifi">Mohammad Y. Alfaifi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Anything that poses a challenge or a threat to our well-being is a stress. Understanding the genetic material and cellular response of rats threatened with Repeated swimming stress provides insights that can influence human health. The aim of the present study was to assess the genetical damage and cytological changes caused by exposure of the test organism (Rattus rattus) to forced swimming stress. For this purpose, animals have been submerged in water path 15 minutes daily for 2 weeks. Following that, we performed a micronuclei (MN) test using MNNCE (Micronucleated normocromatic erythrocytes) and MNPCE (Micronucleated polychromatic erythrocytes), NDI (Nuclear division index) and cytological parameters using NDCI (nuclear division cytotoxicity index), necrotic and apoptotic cells in rat's bone marrow samples. Results showed that there was a slightly but not significant increase in the frequency of micronucleated as well as in cytological parameters in bone marrow cells. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=submergence%20stress" title="submergence stress">submergence stress</a>, <a href="https://publications.waset.org/abstracts/search?q=micronucleus" title=" micronucleus"> micronucleus</a>, <a href="https://publications.waset.org/abstracts/search?q=NDI" title=" NDI"> NDI</a>, <a href="https://publications.waset.org/abstracts/search?q=NDCI" title=" NDCI"> NDCI</a>, <a href="https://publications.waset.org/abstracts/search?q=toxicity" title=" toxicity"> toxicity</a>, <a href="https://publications.waset.org/abstracts/search?q=chromosomal%20aberrations" title=" chromosomal aberrations"> chromosomal aberrations</a> </p> <a href="https://publications.waset.org/abstracts/13505/forced-swim-stress-does-not-induce-structural-chromosomal-aberrations-in-rat-bone-marrow" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13505.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">398</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14528</span> Stress Study in Implants Dental</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Benlebna">M. Benlebna</a>, <a href="https://publications.waset.org/abstracts/search?q=B.%20Serier"> B. Serier</a>, <a href="https://publications.waset.org/abstracts/search?q=B.%20Bachir%20Bouiadjra"> B. Bachir Bouiadjra</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Khalkhal"> S. Khalkhal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study focuses on the mechanical behavior of a dental prosthesis subjected to dynamic loads chewing. It covers a three-dimensional analysis by the finite element method, the level of distribution of equivalent stresses induced in the bone between the implants (depending on the number of implants). The studied structure, consisting of a braced, implant and mandibular bone is subjected to dynamic loading of variable amplitude in three directions corrono-apical, mesial-distal and bucco-lingual. These efforts simulate those of mastication. We show that compared to the implantation of a single implant, implantology using two implants promotes the weakening of the bones. This weakness is all the more likely that the implants are located in close proximity to one another. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stress" title="stress">stress</a>, <a href="https://publications.waset.org/abstracts/search?q=bone" title=" bone"> bone</a>, <a href="https://publications.waset.org/abstracts/search?q=dental%20implant" title=" dental implant"> dental implant</a>, <a href="https://publications.waset.org/abstracts/search?q=distribution" title=" distribution"> distribution</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20levels" title=" stress levels"> stress levels</a>, <a href="https://publications.waset.org/abstracts/search?q=dynamic" title=" dynamic"> dynamic</a>, <a href="https://publications.waset.org/abstracts/search?q=effort" title=" effort"> effort</a>, <a href="https://publications.waset.org/abstracts/search?q=interaction" title=" interaction"> interaction</a>, <a href="https://publications.waset.org/abstracts/search?q=prosthesis" title=" prosthesis"> prosthesis</a> </p> <a href="https://publications.waset.org/abstracts/13570/stress-study-in-implants-dental" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13570.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">407</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14527</span> Epidemiology and Risk Factors of Injury and Stress Fractures in Male and Female Runners</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Balazs%20Patczai">Balazs Patczai</a>, <a href="https://publications.waset.org/abstracts/search?q=Katalin%20Gocze"> Katalin Gocze</a>, <a href="https://publications.waset.org/abstracts/search?q=Gabriella%20Kiss"> Gabriella Kiss</a>, <a href="https://publications.waset.org/abstracts/search?q=Dorottya%20%20Szabo"> Dorottya Szabo</a>, <a href="https://publications.waset.org/abstracts/search?q=Tibor%20Mintal"> Tibor Mintal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Running has become increasingly popular on a global scale in the past decades. Amateur athletes are taking their sport to a new level in an attempt to surpass their performance goals. The aim of our study was to assess the musculoskeletal condition of amateur runners and the prevalence of injuries with a special focus on stress fracture risk. Methods: The cross sectional analysis included ankle mobility, hamstring and lower back flexibility, the use of Renne’s test for iliotibial band syndrome, functional tests for trunk and rotary stability, and measurements of bone density. Data was collected at 2 major half-marathon events in Hungary. Results: Participants (n=134) mean age was 41.76±8.57 years (males: 40.67±8.83, females: 42.08±8.56). Measures of hamstring and lower back flexibility fell into the category of good for both genders (males: 7.13±6.83cm, females: 10.17±6.67cm). No side asymmetry nor gender differences were characteristic in the case of ankle mobility. Trunk stability was significantly better for males than in females (p=0.004). Markers of bone health were in the low normal range for females and were significantly better for males (T-score: p=0.003, T-ratio: p=0.014, Z-score: p=0.034, Z-ratio: p=0.011). 5.2% of females had a previous stress fracture and 24.1% experienced irregular menstrual cycles during the past year. As for the knowledge on the possible association of energy deficiency, menstrual disturbances and their effect on bone health, Only 8.6% of females have heard of the female athlete triad either during their studies or from a health professional. Discussion: The overall musculoskeletal state was satisfactory for both genders both physically and functionally. More attention and effort should be placed on primary and secondary prevention of amateur runners. Very few active women are well informed about the effects of low energy availability and menstrual dysfunction and the negative impact these have on bone health. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20health" title="bone health">bone health</a>, <a href="https://publications.waset.org/abstracts/search?q=flexibility" title=" flexibility"> flexibility</a>, <a href="https://publications.waset.org/abstracts/search?q=running" title=" running"> running</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20fracture" title=" stress fracture"> stress fracture</a> </p> <a href="https://publications.waset.org/abstracts/121546/epidemiology-and-risk-factors-of-injury-and-stress-fractures-in-male-and-female-runners" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/121546.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">129</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14526</span> Effect of Class V Cavity Configuration and Loading Situation on the Stress Concentration</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jia-Yu%20Wu">Jia-Yu Wu</a>, <a href="https://publications.waset.org/abstracts/search?q=Chih-Han%20Chang"> Chih-Han Chang</a>, <a href="https://publications.waset.org/abstracts/search?q=Shu-Fen%20Chuang"> Shu-Fen Chuang</a>, <a href="https://publications.waset.org/abstracts/search?q=Rong-Yang%20Lai"> Rong-Yang Lai</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: This study was to examine the stress distribution of tooth with different class V restorations under different loading situations and geometry by 3D finite element (FE) analysis. `Methods: A series of FE models of mandibular premolars containing class V cavities were constructed using micro-CT. The class V cavities were assigned as the combinations of different cavity depths x occlusal -gingival heights: 1x2, 1x4, 2x2, and 2x4 mm. Three alveolar bone loss conditions were examined: 0, 1, and 2 mm. 200 N force was exerted on the buccal cusp tip under various directions (vertical, V; obliquely 30° angled, O; oblique and parallel the individual occlusal cavity wall, P). A 3-D FE analysis was performed and the von-Mises stress was used to summarize the data of stress distribution and maximum stress. Results: The maximal stress did not vary in different alveolar bone heights. For each geometry, the maximal stress was found at bilateral corners of the cavity. The peak stress of restorations was significantly higher under load P compared to those under loads V and O while the latter two were similar. 2x2mm cavity exhibited significantly increased (2.88 fold) stress under load P compared to that under load V, followed by 1x2mm (2.11 fold), 2x4mm (1.98 fold) and 1x4mm (1.1fold). Conclusion: Load direction causes the greatest impact on the results of stress, while the effect of alveolar bone loss is minor. Load direction parallel to the cavity wall may enhance the stress concentration especially in deep and narrow class cavities. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=class%20v%20restoration" title="class v restoration">class v restoration</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20analysis" title=" finite element analysis"> finite element analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=loading%20situation" title=" loading situation"> loading situation</a>, <a href="https://publications.waset.org/abstracts/search?q=stress" title=" stress"> stress</a> </p> <a href="https://publications.waset.org/abstracts/66073/effect-of-class-v-cavity-configuration-and-loading-situation-on-the-stress-concentration" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/66073.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">250</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14525</span> Suitability Evaluation of CNW as Scaffold for Osteoblast</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hoo%20Cheol%20Lee">Hoo Cheol Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Dae%20Seung%20Kim"> Dae Seung Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Sang%20Myung%20Jung"> Sang Myung Jung</a>, <a href="https://publications.waset.org/abstracts/search?q=Gwang%20Heum%20Yoon"> Gwang Heum Yoon</a>, <a href="https://publications.waset.org/abstracts/search?q=Hwa%20Sung%20Shin"> Hwa Sung Shin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Loss of bone tissue can occur due to a bone tissue disease and aging or fracture. Renewable formation of bone is mainly made by its differentiation and metabolism. For this reason, osteoblasts have been studied for regeneration of bone tissue. So, tissue engineering has attracted attention as a recovery means. In tissue engineering, a particularly important factor is a scaffold that supports cell growth. For osteoblast scaffold, we used the cellulose nanowhisker (CNW) extracted from marine organism. CNW is one of an abundant material obtained from a number of plants and animals. CNW is polymer consisting of monomer cellulose and this composition offers biodegradability and biocompatibility to CNW. Mechanical strength of CNW is superior to the existing natural polymers. In addition, substances of marine origin have a low risk of secondary infection by bacteria and pathogen in contrast with those of land-derived. For evaluating its suitability as an osteoblast scaffold, we fabricate CNW film for osteoblast culture and performed the MTT assay and ALP assay to confirm its cytotoxicity and effect on differentiation. Taking together these results, we assessed CNW is a potential candidate of a material for bone tissue regeneration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20regeneration" title="bone regeneration">bone regeneration</a>, <a href="https://publications.waset.org/abstracts/search?q=cellulose%20nanowhisker" title=" cellulose nanowhisker"> cellulose nanowhisker</a>, <a href="https://publications.waset.org/abstracts/search?q=marine%20derived%20material" title=" marine derived material"> marine derived material</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoblast" title=" osteoblast"> osteoblast</a> </p> <a href="https://publications.waset.org/abstracts/7802/suitability-evaluation-of-cnw-as-scaffold-for-osteoblast" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7802.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">353</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14524</span> Simplified Linearized Layering Method for Stress Intensity Factor Determination</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jeries%20J.%20Abou-Hanna">Jeries J. Abou-Hanna</a>, <a href="https://publications.waset.org/abstracts/search?q=Bradley%20Storm"> Bradley Storm</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper looks to reduce the complexity of determining stress intensity factors while maintaining high levels of accuracy by the use of a linearized layering approach. Many techniques for stress intensity factor determination exist, but they can be limited by conservative results, requiring too many user parameters, or by being too computationally intensive. Multiple notch geometries with various crack lengths were investigated in this study to better understand the effectiveness of the proposed method. By linearizing the average stresses in radial layers around the crack tip, stress intensity factors were found to have error ranging from -10.03% to 8.94% when compared to analytically exact solutions. This approach proved to be a robust and efficient method of accurately determining stress intensity factors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fracture%20mechanics" title="fracture mechanics">fracture mechanics</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20method" title=" finite element method"> finite element method</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20intensity%20factor" title=" stress intensity factor"> stress intensity factor</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20linearization" title=" stress linearization"> stress linearization</a> </p> <a href="https://publications.waset.org/abstracts/146820/simplified-linearized-layering-method-for-stress-intensity-factor-determination" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/146820.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">149</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14523</span> Alteration of Bone Strength in Osteoporosis of Mouse Femora: Computational Study Based on Micro CT Images</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Changsoo%20Chon">Changsoo Chon</a>, <a href="https://publications.waset.org/abstracts/search?q=Sangkuy%20Han"> Sangkuy Han</a>, <a href="https://publications.waset.org/abstracts/search?q=Donghyun%20Seo"> Donghyun Seo</a>, <a href="https://publications.waset.org/abstracts/search?q=Jihyung%20Park"> Jihyung Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Bokku%20Kang"> Bokku Kang</a>, <a href="https://publications.waset.org/abstracts/search?q=Hansung%20Kim"> Hansung Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Keyoungjin%20Chun"> Keyoungjin Chun</a>, <a href="https://publications.waset.org/abstracts/search?q=Cheolwoong%20Ko"> Cheolwoong Ko</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The purpose of the study is to develop a finite element model based on 3D bone structural images of Micro-CT and to analyze the stress distribution for the osteoporosis mouse femora. In this study, results of finite element analysis show that the early osteoporosis of mouse model decreased a bone density in trabecular region; however, the bone density in cortical region increased. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=micro-CT" title="micro-CT">micro-CT</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20analysis" title=" finite element analysis"> finite element analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title=" osteoporosis"> osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20strength" title=" bone strength"> bone strength</a> </p> <a href="https://publications.waset.org/abstracts/48362/alteration-of-bone-strength-in-osteoporosis-of-mouse-femora-computational-study-based-on-micro-ct-images" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48362.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">369</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14522</span> Checking Planetary Clutch on the Romania Tractor Using Mathematical Equations</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Vahedi%20Torshizi">Mohammad Vahedi Torshizi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this investigation, at first, bending stress, contact stress, Safety factor of bending and Safety factor of contact between sun gear and planet gear tooth was determined using mathematical equations. Also, The amount of Sun Revolution in, Speed carrier, power Transmitted of the sun, sun torque, sun peripheral speed, Enter the tangential force gears, was calculated using mathematical equations. According to the obtained results, maximum of bending stress and contact stress occurred in three plantary and low status of four plantary. Also, maximum of Speed carrier, sun peripheral speed, Safety factor of bending and Safety factor of contact obtained in four plantary and maximum of power Transmitted of the sun, Enter the tangential force gears, bending stress and contact stress was in three pantry and factors And other factors were equal in the two planets. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bending%20stress" title="bending stress">bending stress</a>, <a href="https://publications.waset.org/abstracts/search?q=contact%20stress" title=" contact stress"> contact stress</a>, <a href="https://publications.waset.org/abstracts/search?q=plantary" title=" plantary"> plantary</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical%20equations" title=" mathematical equations"> mathematical equations</a> </p> <a href="https://publications.waset.org/abstracts/58238/checking-planetary-clutch-on-the-romania-tractor-using-mathematical-equations" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58238.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">292</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14521</span> Bone Mineral Density in Type 2 Diabetes Mellitus Postmenopausal Egyptian Female Patients: Correlation with Fetuin-A Level and Metabolic Parameters</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20A.%20M.%20Shoaib">Ahmed A. M. Shoaib</a>, <a href="https://publications.waset.org/abstracts/search?q=Heba%20A.%20Esaily"> Heba A. Esaily</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahmoud%20M.%20Emara"> Mahmoud M. Emara</a>, <a href="https://publications.waset.org/abstracts/search?q=Eman%20A.%20E.%20Badr"> Eman A. E. Badr</a>, <a href="https://publications.waset.org/abstracts/search?q=Amany%20S.%20Khalifa"> Amany S. Khalifa</a>, <a href="https://publications.waset.org/abstracts/search?q=Mayada%20M.%20M."> Mayada M. M.</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdel-Raizk"> Abdel-Raizk </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: DM is associated with metabolic bone diseases, osteoporosis, low-impact fractures and falls in geriatrics. Fetuin-A, which is a serum protein produced by the liver and promotes bone mineralization, is an independent risk factor for type 2 diabetes. Aim: Evaluation of fetuin-A level and bone mineral density in postmenopausal Egyptian female patients with type 2 diabetes mellitus and their correlation with each other & with other metabolic parameters. Patients and methods: Seventy postmenopausal female patients with type II diabetes and thirty postmenopausal female as control were included in this study. Measurement of Fetuin-A together with metabolic parameters and DXA in wrist, hip and spine, ALP, CBC, FBS, PP2H and HBA1c was done in all participants. Results: - Fetuin-A level was found to be highly significant (p< 0.001) between diabetic and nondiabetic groups and negatively correlated with BMD in spine. No difference in BMD was found between patients and control groups while significant negative correlation was found between FBS and hip BMD (<0.05) and between 2hpp and HBA1c with spine BMD in the diabetic group (<0.05). Osteoporosis represented 12.9% in spine area and 7.2% in hip and wrist areas in diabetic patients, while osteopenia were found in 58.5%, 57.1%, and 37.1% in diabetic patients in spine, wrist, and hip respectively. Conclusion: - type II diabetes cannot be considered as a risk factor for osteoporosis; while glycemic parameters (FBS, 2hpp & HBA1c) and serum Fetuin-A levels were correlated with BMD in diabetics. Good glycemic control can be protective against osteoporosis in diabetic elderly. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fetuin-A" title="fetuin-A">fetuin-A</a>, <a href="https://publications.waset.org/abstracts/search?q=BMD" title=" BMD"> BMD</a>, <a href="https://publications.waset.org/abstracts/search?q=postmenopausal" title=" postmenopausal"> postmenopausal</a>, <a href="https://publications.waset.org/abstracts/search?q=DM%20type%20II" title=" DM type II"> DM type II</a> </p> <a href="https://publications.waset.org/abstracts/48745/bone-mineral-density-in-type-2-diabetes-mellitus-postmenopausal-egyptian-female-patients-correlation-with-fetuin-a-level-and-metabolic-parameters" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48745.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">269</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14520</span> Induced Bone Tissue Temperature in Drilling Procedures: A Comparative Laboratory Study with and without Lubrication</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=L.%20Roseiro">L. Roseiro</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Veiga"> C. Veiga</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20Maranha"> V. Maranha</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Neto"> A. Neto</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Laraqi"> N. Laraqi</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Ba%C3%AFri"> A. Baïri</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Alilat"> N. Alilat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In orthopedic surgery there are various situations in which the surgeon needs to implement methods of cutting and drilling the bone. With this type of procedure the generated friction leads to a localized increase in temperature, which may lead to the bone necrosis. Recognizing the importance of studying this phenomenon, an experimental evaluation of the temperatures developed during the procedure of drilling bone has been done. Additionally the influence of the use of the procedure with / without additional lubrication during drilling of bone has also been done. The obtained results are presented and discussed and suggests an advantage in using additional lubrication as a way to minimize the appearance of bone tissue necrosis during bone drilling procedures. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20necrosis" title="bone necrosis">bone necrosis</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20drilling" title=" bone drilling"> bone drilling</a>, <a href="https://publications.waset.org/abstracts/search?q=thermography" title=" thermography"> thermography</a>, <a href="https://publications.waset.org/abstracts/search?q=surgery" title=" surgery"> surgery</a> </p> <a href="https://publications.waset.org/abstracts/16605/induced-bone-tissue-temperature-in-drilling-procedures-a-comparative-laboratory-study-with-and-without-lubrication" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16605.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">604</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14519</span> Static and Dynamic Load on Hip Contact of Hip Prosthesis and Thai Femoral Bones</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20Chalernpon">K. Chalernpon</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Aroonjarattham"> P. Aroonjarattham</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Aroonjarattham"> K. Aroonjarattham</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Total hip replacement had been one of the most successful operations in hip arthritis surgery. The purpose of this research had been to develop a dynamic hip contact of Thai femoral bone to analyze the stress distribution on the implant and the strain distribution on the bone model under daily activities and compared with the static load simulation. The results showed the different of maximum von Mises stress 0.14 percent under walking and 0.03 percent under climbing stair condition and the different of equivalent total strain 0.52 percent under walking and 0.05 percent under climbing stair condition. The muscular forces should be evaluated with dynamic condition to reduce the maximum von Mises stress and equivalent total strain. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dynamic%20loading" title="dynamic loading">dynamic loading</a>, <a href="https://publications.waset.org/abstracts/search?q=static%20load" title=" static load"> static load</a>, <a href="https://publications.waset.org/abstracts/search?q=hip%20prosthesis" title=" hip prosthesis"> hip prosthesis</a>, <a href="https://publications.waset.org/abstracts/search?q=Thai%20femur" title=" Thai femur"> Thai femur</a>, <a href="https://publications.waset.org/abstracts/search?q=femoral%20bone" title=" femoral bone"> femoral bone</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20analysis" title=" finite element analysis"> finite element analysis</a> </p> <a href="https://publications.waset.org/abstracts/17096/static-and-dynamic-load-on-hip-contact-of-hip-prosthesis-and-thai-femoral-bones" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17096.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">351</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14518</span> Simulated Mechanical Analysis on Hydroxyapatite Coated Porous Polylactic Acid Scaffold for Bone Grafting</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ala%20Abobakr%20Abdulhafidh%20Al-Dubai">Ala Abobakr Abdulhafidh Al-Dubai</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bone loss has risen due to fractures, surgeries, and traumatic injuries. Scientists and engineers have worked over the years to find solutions to heal and accelerate bone regeneration. The bone grafting technique has been utilized, which projects significant improvement in the bone regeneration area. An extensive study is essential on the relation between the mechanical properties of bone scaffolds and the pore size of the scaffolds, as well as the relation between the mechanical properties of bone scaffolds with the development of bioactive coating on the scaffolds. In reducing the cost and time, a mechanical simulation analysis is beneficial to simulate both relations. Therefore, this study highlights the simulated mechanical analyses on three-dimensional (3D) polylactic acid (PLA) scaffolds at two different pore sizes (P: 400 and 600 μm) and two different internals distances of (D: 600 and 900 μm), with and without the presence of hydroxyapatite (HA) coating. The 3D scaffold models were designed using SOLIDWORKS software. The respective material properties were assigned with the fixation of boundary conditions on the meshed 3D models. Two different loads were applied on the PLA scaffolds, including side loads of 200 N and vertical loads of 2 kN. While only vertical loads of 2 kN were applied on the HA coated PLA scaffolds. The PLA scaffold P600D900, which has the largest pore size and maximum internal distance, generated the minimum stress under the applied vertical load. However, that same scaffold became weaker under the applied side load due to the high construction gap between the pores. The development of HA coating on top of the PLA scaffolds induced greater stress generation compared to the non-coated scaffolds which is tailorable for bone implantation. This study concludes that the pore size and the construction of HA coating on bone scaffolds affect the mechanical strength of the bone scaffolds. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite%20coating" title="hydroxyapatite coating">hydroxyapatite coating</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20scaffold" title=" bone scaffold"> bone scaffold</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20simulation" title=" mechanical simulation"> mechanical simulation</a>, <a href="https://publications.waset.org/abstracts/search?q=three-dimensional%20%283D%29" title=" three-dimensional (3D)"> three-dimensional (3D)</a>, <a href="https://publications.waset.org/abstracts/search?q=polylactic%20acid%20%28PLA%29." title=" polylactic acid (PLA)."> polylactic acid (PLA).</a> </p> <a href="https://publications.waset.org/abstracts/182078/simulated-mechanical-analysis-on-hydroxyapatite-coated-porous-polylactic-acid-scaffold-for-bone-grafting" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/182078.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">65</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14517</span> Stress Intensity Factor for Dynamic Cracking of Composite Material by X-FEM Method</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=S.%20Lecheb">S. Lecheb</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Nour"> A. Nour</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Chellil"> A. Chellil</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Mechakra"> H. Mechakra</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Hamad"> N. Hamad</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Kebir"> H. Kebir</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The work involves develops attended by a numerical execution of the eXtend Finite Element Method premises a measurement by the fracture process cracked so many cracked plates an application will be processed for the calculation of the stress intensity factor SIF. In the first we give in statically part the distribution of stress, displacement field and strain of composite plate in two cases uncrack/edge crack, also in dynamical part the first six modes shape. Secondly, we calculate Stress Intensity Factor SIF for different orientation angle θ of central crack with length (2a=0.4mm) in plan strain condition, KI and KII are obtained for mode I and mode II respectively using X-FEM method. Finally from crack inclined involving mixed modes results, the comparison we chose dangerous inclination and the best crack angle when K is minimal. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stress%20intensity%20factor%20%28SIF%29" title="stress intensity factor (SIF)">stress intensity factor (SIF)</a>, <a href="https://publications.waset.org/abstracts/search?q=crack%20orientation" title=" crack orientation"> crack orientation</a>, <a href="https://publications.waset.org/abstracts/search?q=glass%2Fepoxy" title=" glass/epoxy"> glass/epoxy</a>, <a href="https://publications.waset.org/abstracts/search?q=natural%20frequencies" title=" natural frequencies"> natural frequencies</a>, <a href="https://publications.waset.org/abstracts/search?q=X-FEM" title=" X-FEM"> X-FEM</a> </p> <a href="https://publications.waset.org/abstracts/5631/stress-intensity-factor-for-dynamic-cracking-of-composite-material-by-x-fem-method" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/5631.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">520</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14516</span> Effects of Egg Yolk Peptide on the Retardation of Bone Growth Induced by Low-Calcium Diets</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kang-Hyun%20Leem">Kang-Hyun Leem</a>, <a href="https://publications.waset.org/abstracts/search?q=Myung-Gyou%20Kim"> Myung-Gyou Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Hye%20Kyung%20Kim"> Hye Kyung Kim </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Eggs have long been an important contributor to the nutritional quality of the human, and recognized as a very valuable source of proteins for human nutrition. Egg yolk is composed of various important chemical substances for human health. Growth means not only the increase of body weight but also the elongation of height and the enlargement of each organ's anatomical and morphological size. A calcium shortage causes the growth retardation on the body growth. In this study, we examined the therapeutic effects of egg yolk peptide (EYP) on the retardation of the longitudinal bone growth induced by low-calcium diet (0.05%) in adolescent rats. Low calcium diets were administrated for 15 days. During the last five days, calcium and/or vitamin D and/or EYP were administrated. The body weights, longitudinal bone growth rates, the heights of growth plates, and bone morphogenetic protein (BMP)-2 and insulin-like growth factor (IGF)-1 expressions were measured using histochemical analysis. Low calcium diets caused the significant reduction in body weight gains and the longitudinal bone growth. The heights of growth plates and the expressions of BMP-2 and IGF-1 showed the impairment of body growth as well. Calcium and/or vitamin D administration could not significantly increase the longitudinal bone growth. However, calcium, vitamin D, and EYP administration significantly increased the bone growth, the growth plate height, and BMP-2 and IGF-1 expressions. These results suggest that EYP enhances the longitudinal bone growth in the calcium and/or vitamin D deficiency and it could be a promising agent for the treatment of children suffering from malnutrition. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=egg%20yolk%20peptide" title="egg yolk peptide">egg yolk peptide</a>, <a href="https://publications.waset.org/abstracts/search?q=low-calcium%20diet" title=" low-calcium diet"> low-calcium diet</a>, <a href="https://publications.waset.org/abstracts/search?q=longitudinal%20bone%20growth" title=" longitudinal bone growth"> longitudinal bone growth</a>, <a href="https://publications.waset.org/abstracts/search?q=morphogenetic%20protein-2" title=" morphogenetic protein-2"> morphogenetic protein-2</a>, <a href="https://publications.waset.org/abstracts/search?q=insulin-like%20growth%20factor-1" title=" insulin-like growth factor-1"> insulin-like growth factor-1</a>, <a href="https://publications.waset.org/abstracts/search?q=vitamin%20D" title=" vitamin D"> vitamin D</a> </p> <a href="https://publications.waset.org/abstracts/11287/effects-of-egg-yolk-peptide-on-the-retardation-of-bone-growth-induced-by-low-calcium-diets" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11287.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">450</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14515</span> Obtain the Stress Intensity Factor (SIF) in a Medium Containing a Penny-Shaped Crack by the Ritz Method</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Tavangari">A. Tavangari</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Salehzadeh"> N. Salehzadeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the crack growth analysis, the Stress Intensity Factor (SIF) is a fundamental prerequisite. In the present study, the mode I stress intensity factor (SIF) of three-dimensional penny-Shaped crack is obtained in an isotropic elastic cylindrical medium with arbitrary dimensions under arbitrary loading at the top of the cylinder, by the semi-analytical method based on the Rayleigh-Ritz method. This method that is based on minimizing the potential energy amount of the whole of the system, gives a very close results to the previous studies. Defining the displacements (elastic fields) by hypothetical functions in a defined coordinate system is the base of this research. So for creating the singularity conditions at the tip of the crack the appropriate terms should be found. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=penny-shaped%20crack" title="penny-shaped crack">penny-shaped crack</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20intensity%20factor" title=" stress intensity factor"> stress intensity factor</a>, <a href="https://publications.waset.org/abstracts/search?q=fracture%20mechanics" title=" fracture mechanics"> fracture mechanics</a>, <a href="https://publications.waset.org/abstracts/search?q=Ritz%20method" title=" Ritz method"> Ritz method</a> </p> <a href="https://publications.waset.org/abstracts/9300/obtain-the-stress-intensity-factor-sif-in-a-medium-containing-a-penny-shaped-crack-by-the-ritz-method" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9300.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">370</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14514</span> An Assessment of the Risk and Protective Factors Impacting Criminal Gang Involvement among At-Risk Boys Resident at a Juvenile Home in Trinidad and Tobago: The Peer/Individual Domain of the Risk Factor Prevention ParadIGM </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dianne%20Williams">Dianne Williams</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study examined the peer/individual domain of the Risk Factor Prevention Paradigm (RFPP) to assess the risk and protective factors that impact criminal gang involvement among at-risk males residing in a juvenile home in Trinidad and Tobago. The RFPP allows for the identification of both risk and protective factors in a single, holistic framework to identify the relationship between risk factors, protective factors, and criminal gang involvement among at-risk male adolescents. Findings showed that having anti-social peers was the most significant risk factor associated with criminal gang involvement, while the most significant protective factor was having a positive social attitude. Moreover, while 65% of the boys reported never having been in a gang, 70% reported having hit, struck or used a weapon against someone, while 52% reported being involved in other violent incidents on more than two occasions. This suggests that while involvement with criminal gangs may not be common among this population, predisposing behavioral patterns are present. Results are expected to assist in the development of targeted strategies to reduce the attractiveness of gang membership. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=risk%20factor%20prevention%20paradigm" title="risk factor prevention paradigm">risk factor prevention paradigm</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20factors" title=" risk factors"> risk factors</a>, <a href="https://publications.waset.org/abstracts/search?q=protective%20factors" title=" protective factors"> protective factors</a>, <a href="https://publications.waset.org/abstracts/search?q=peer%2Findividual%20domain" title=" peer/individual domain"> peer/individual domain</a>, <a href="https://publications.waset.org/abstracts/search?q=gang%20involvement" title=" gang involvement"> gang involvement</a>, <a href="https://publications.waset.org/abstracts/search?q=at-risk%20youth" title=" at-risk youth"> at-risk youth</a>, <a href="https://publications.waset.org/abstracts/search?q=trinidad%20and%20tobago" title=" trinidad and tobago"> trinidad and tobago</a>, <a href="https://publications.waset.org/abstracts/search?q=juvenile%20home" title=" juvenile home"> juvenile home</a> </p> <a href="https://publications.waset.org/abstracts/35675/an-assessment-of-the-risk-and-protective-factors-impacting-criminal-gang-involvement-among-at-risk-boys-resident-at-a-juvenile-home-in-trinidad-and-tobago-the-peerindividual-domain-of-the-risk-factor-prevention-paradigm" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/35675.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">611</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14513</span> An Analysis of the Impact of Immunosuppression upon the Prevalence and Risk of Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aruha%20Khan">Aruha Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Brynn%20E.%20Kankel"> Brynn E. Kankel</a>, <a href="https://publications.waset.org/abstracts/search?q=Paraskevi%20Papadopoulou"> Paraskevi Papadopoulou</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years, extensive research upon ‘stress’ has provided insight into its two distinct guises, namely the short–term (fight–or–flight) response versus the long–term (chronic) response. Specifically, the long–term or chronic response is associated with the suppression or dysregulation of immune function. It is also widely noted that the occurrence of cancer is greatly correlated to the suppression of the immune system. It is thus necessary to explore the impact of long–term or chronic stress upon the prevalence and risk of cancer. To what extent can the dysregulation of immune function caused by long–term exposure to stress be controlled or minimized? This study focuses explicitly upon immunosuppression due to its ability to increase disease susceptibility, including cancer itself. Based upon an analysis of the literature relating to the fundamental structure of the immune system alongside the prospective linkage of chronic stress and the development of cancer, immunosuppression may not necessarily correlate directly to the acquisition of cancer—although it remains a contributing factor. A cross-sectional analysis of the survey data from the University of Tennessee Medical Center (UTMC) and Harvard Medical School (HMS) will provide additional supporting evidence (or otherwise) for the hypothesis of the study about whether immunosuppression (caused by the chronic stress response) notably impacts the prevalence of cancer. Finally, a multidimensional framework related to education on chronic stress and its effects is proposed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=immune%20system" title="immune system">immune system</a>, <a href="https://publications.waset.org/abstracts/search?q=immunosuppression" title=" immunosuppression"> immunosuppression</a>, <a href="https://publications.waset.org/abstracts/search?q=long%E2%80%93term%20%28chronic%29%20stress" title=" long–term (chronic) stress"> long–term (chronic) stress</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20of%20cancer" title=" risk of cancer"> risk of cancer</a> </p> <a href="https://publications.waset.org/abstracts/118862/an-analysis-of-the-impact-of-immunosuppression-upon-the-prevalence-and-risk-of-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/118862.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">140</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14512</span> Severe Bone Marrow Edema on Sacroiliac Joint MRI Increases the Risk of Low BMD in Patients with Axial Spondyloarthritis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kwi%20Young%20Kang">Kwi Young Kang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: To determine the association between inflammatory and structural lesions on sacroiliac joint (SIJ) MRI and BMD and to identify risk factors for low BMD in patients with axial spondyloarthritis (axSpA). Methods: Seventy-six patients who fulfilled the ASAS axSpA criteria were enrolled. All underwent SIJ MRI and BMD measurement at the lumbar spine, femoral neck, and total hip. Inflammatory and structural lesions on SIJ MRI were scored. Laboratory tests and assessment of radiographic and disease activity were performed at the time of MRI. The association between SIJ MRI findings and BMD was evaluated. Results: Among the 76 patients, 14 (18%) had low BMD. Patients with low BMD showed significantly higher bone marrow edema (BME) and deep BME scores on MRI than those with normal BMD (p<0.047 and 0.007, respectively). Inflammatory lesions on SIJ MRI correlated with BMD at the femoral neck and total hip. Multivariate analysis identified the presence of deep BME on SIJ MRI, increased CRP, and sacroiliitis on X-ray as risk factors for low BMD (OR: 5.6, 14.6, and 2.5, respectively). Conclusion: The presence of deep BME on SIJ MRI, increased CRP levels, and severity of sacroiliitis on X-ray were independent risk factors for low BMD. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=axial%20spondyloarthritis" title="axial spondyloarthritis">axial spondyloarthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=sacroiliac%20joint%20MRI" title=" sacroiliac joint MRI"> sacroiliac joint MRI</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20mineral%20density" title=" bone mineral density"> bone mineral density</a>, <a href="https://publications.waset.org/abstracts/search?q=sacroiliitis" title=" sacroiliitis"> sacroiliitis</a> </p> <a href="https://publications.waset.org/abstracts/39768/severe-bone-marrow-edema-on-sacroiliac-joint-mri-increases-the-risk-of-low-bmd-in-patients-with-axial-spondyloarthritis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/39768.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">535</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14511</span> Female Athlete Triad: How Much Is Known</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nadine%20Abuqtaish">Nadine Abuqtaish</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Females’ participation in athletic sports events has increased in the last decades, and the discovery of eating disorders and menstrual dysfunction has been evident since the early 1980s. The term “Female athlete triad” was initially defined by the Task Force on Women’s Issues of the American College of Sports Medicine (ACSM) in 1992. Menstrual irregularities have been prevalent in competitive female athletes, especially in their adolescence and early adulthood age. Nutritional restrictions to maintain a certain physique and lean look are sought to be advantageous in female athletes such as gymnastics, cheerleading, or weight-sensitive sports such as endurance sports (cycling and marathoners). This stress places the female at risk of irregularities in their menstrual cycle which can lead them to lose their circadian estrogen levels. Estrogen is an important female reproductive hormone that plays a role in maintaining bone mass. Bone mineral density peaks by the age 25. Inadequate estrogen due to missed menstrual cycle or amenorrhea has been estimated to cause a yearly loss of 2% of bone mass, increasing the risk of osteoporosis in the postmenopausal phase. This paper is intended to have a better depth understanding of whether female athletes are being monitored by their official entities or coaches. A qualitative research method through online search engines and keywords “females, athletes, triad, amenorrhea, anorexia, osteoporosis” were used to collect the available primary sources from official public library databases. The latest consensus was published in 2014 by the Female Athlete Triad Coalition and the need for further research and emphasis on this issue is still lacking. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=female" title="female">female</a>, <a href="https://publications.waset.org/abstracts/search?q=athlete" title=" athlete"> athlete</a>, <a href="https://publications.waset.org/abstracts/search?q=triad" title=" triad"> triad</a>, <a href="https://publications.waset.org/abstracts/search?q=amenorrhea" title=" amenorrhea"> amenorrhea</a>, <a href="https://publications.waset.org/abstracts/search?q=anorexia" title=" anorexia"> anorexia</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20loss" title=" bone loss"> bone loss</a> </p> <a href="https://publications.waset.org/abstracts/152724/female-athlete-triad-how-much-is-known" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152724.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">66</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14510</span> Finite Element Analysis of Mini-Plate Stabilization of Mandible Fracture</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Piotr%20Wadolowski">Piotr Wadolowski</a>, <a href="https://publications.waset.org/abstracts/search?q=Grzegorz%20Krzesinski"> Grzegorz Krzesinski</a>, <a href="https://publications.waset.org/abstracts/search?q=Piotr%20Gutowski"> Piotr Gutowski</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the presented investigation is to recognize the possible mechanical issues of mini-plate connection used to treat mandible fractures and to check the impact of different factors for the stresses and displacements within the bone-stabilizer system. The mini-plate osteosynthesis technique is a common type of internal fixation using metal plates connected to the fractured bone parts by a set of screws. The selected two types of plate application methodology used by maxillofacial surgeons were investigated in the work. Those patterns differ in location and number of plates. The bone geometry was modeled on the base of computed tomography scans of hospitalized patient done just after mini-plate application. The solid volume geometry consisting of cortical and cancellous bone was created based on gained cloud of points. Temporomandibular joint and muscle system were simulated to imitate the real masticatory system behavior. Finite elements mesh and analysis were performed by ANSYS software. To simulate realistic connection behavior nonlinear contact conditions were used between the connecting elements and bones. The influence of the initial compression of the connected bone parts or the gap between them was analyzed. Nonlinear material properties of the bone tissues and elastic-plastic model of titanium alloy were used. The three cases of loading assuming the force of magnitude of 100N acting on the left molars, the right molars and the incisors were investigated. Stress distribution within connecting plate shows that the compression of the bone parts in the connection results in high stress concentration in the plate and the screws, however the maximum stress levels do not exceed material (titanium) yield limit. There are no significant differences between negative offset (gap) and no-offset conditions. The location of the external force influences the magnitude of stresses around both the plate and bone parts. Two-plate system gives generally lower von Misses stress under the same loading than the one-plating approach. Von Mises stress distribution within the cortical bone shows reduction of high stress field for the cases without the compression (neutral initial contact). For the initial prestressing there is a visible significant stress increase around the fixing holes at the bottom mini-plate due to the assembly stress. The local stress concentration may be the reason of bone destruction in those regions. The performed calculations prove that the bone-mini-plate system is able to properly stabilize the fractured mandible bone. There is visible strong dependency between the mini-plate location and stress distribution within the stabilizer structure and the surrounding bone tissue. The results (stresses within the bone tissues and within the devices, relative displacements of the bone parts at the interface) corresponding to different models of the connection provide a basis for the mechanical optimization of the mini-plate connections. The results of the performed numerical simulations were compared to clinical observation. They provide information helpful for better understanding of the load transfer in the mandible with the stabilizer and for improving stabilization techniques. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20modeling" title="finite element modeling">finite element modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=mandible%20fracture" title=" mandible fracture"> mandible fracture</a>, <a href="https://publications.waset.org/abstracts/search?q=mini-plate%20connection" title=" mini-plate connection"> mini-plate connection</a>, <a href="https://publications.waset.org/abstracts/search?q=osteosynthesis" title=" osteosynthesis"> osteosynthesis</a> </p> <a href="https://publications.waset.org/abstracts/58124/finite-element-analysis-of-mini-plate-stabilization-of-mandible-fracture" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58124.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">252</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14509</span> Occupational Stress and Lipid Profile among Drivers in Ismailia City, Egypt</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amani%20Waheed">Amani Waheed</a>, <a href="https://publications.waset.org/abstracts/search?q=Adel%20Mishriky"> Adel Mishriky</a>, <a href="https://publications.waset.org/abstracts/search?q=Rasha%20Farouk"> Rasha Farouk</a>, <a href="https://publications.waset.org/abstracts/search?q=Essam%20%20Abdallah"> Essam Abdallah</a>, <a href="https://publications.waset.org/abstracts/search?q=Sarah%20Hussein"> Sarah Hussein</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Occupational stress plays a crucial role in professional drivers' health. They are exposed to high workloads, low physical activity, high demand and low decisions as well as poor lifestyle factors including poor diet, sedentary work, and smoking. Dyslipidemia is a well-established modifiable cardiovascular risk factor. Occupational stress and other forms of chronic stress have been associated with raised levels of atherogenic lipids. Although stress management has some evidence in improving lipid profile, the association between occupational stress and dyslipidemia is not clear. Objectives: To assess the relational between occupational stress and lipid profile among professional drivers. Methodology: A cross-sectional study conducted at a large company in Ismailia City, Egypt, where, 131 professional drivers divided into 44 car drivers, 43 bus drivers, and 44 truck drivers were eligible after applying exclusion criteria. Occupational stress index (OSI), non-occupational risk factors of dyslipidemia were assessed using interview structured questionnaire. Blood pressure, body mass index (BMI) and lipid profile were measured. Results: The mean of total OSI score was 79.98 ± 6.14. The total OSI score is highest among truck drivers (82.16 ± 4.62), then bus drivers (80.26 ± 6.02) and lowest among car drivers (77.55 ± 6.79) with statistically significant. Eighty percent had Dyslipidemia. The duration of driving hours per day, exposure to passive smoking and increased BMI were the risk factors. No statistical significance between Total OSI score and dyslipidemia. Using, logistic regression analysis, occupational stress, duration of driving hours per day, and BMI were positive significant predictors for dyslipidemia. Conclusion: Professional drivers are exposed to occupational stress. A high proportion of drivers have dyslipidemia. Total OSI score doesn't have statistically significant relation with dyslipidemia. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=body%20mass%20index" title="body mass index">body mass index</a>, <a href="https://publications.waset.org/abstracts/search?q=dyslipidaemia" title=" dyslipidaemia"> dyslipidaemia</a>, <a href="https://publications.waset.org/abstracts/search?q=occupational%20stress" title=" occupational stress"> occupational stress</a>, <a href="https://publications.waset.org/abstracts/search?q=professional%20drivers" title=" professional drivers"> professional drivers</a> </p> <a href="https://publications.waset.org/abstracts/96336/occupational-stress-and-lipid-profile-among-drivers-in-ismailia-city-egypt" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96336.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">174</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=bone%20stress%20risk%20factor&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=bone%20stress%20risk%20factor&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=bone%20stress%20risk%20factor&page=4">4</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=bone%20stress%20risk%20factor&page=5">5</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=bone%20stress%20risk%20factor&page=6">6</a></li> <li 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