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Leuven surgeons transplant four organs during one procedure in a toddler | UZ Leuven

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The young patient was successfully operated on and is doing well. " /> <meta property="og:description" content="A team of UZ Leuven doctors has recently replaced all abdominal organs in a toddler for the first time in Belgium: stomach, liver, pancreas as well as the small intestine were transplanted in one procedure. The young patient was successfully operated on and is doing well. 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The young patient was successfully operated on and is doing well. </div> <div class="toc hero__toc"> <div class="toc__title">On this page</div> <ul class="toc__list"> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#complex-procedure">Complex procedure</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#multivisceral-transplants-at-uz-leuven">Multivisceral transplants at UZ Leuven</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#lift-members">LIFT members</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#related">Related</a> </span> </li> </ul> </div> </div> <div class="hero__media"> <figure class="media"> <div class="media__content"> <img class="media__img hero__media__img" src="https://wmimages.uzleuven.be/styles/57eef194148f5468c7316818506af58a703ab731/2023-12/50617.jpg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6Imluc2lkZSIsIndpZHRoIjoxMzIwLCJoZWlnaHQiOjgwMCwid2l0aG91dEVubGFyZ2VtZW50Ijp0cnVlfX1d&amp;sign=633547d2ea94aba0088f2b42164464a5960291a14c0cde7fc6b48adad7b8e830" alt="" /> <figcaption class="media__caption"> <span class="media__caption__text"><p>漏 UZ Leuven</p> </span> </figcaption> </div> </figure> </div> </header> <div class="l-content"> <article class="l-content__cbs "> <div class="cbs "> <div id="68fdd6ea-58f0-4158-80c5-19bfe31be1d2" class="block--text text"> <p>A transplantation of all abdominal organs, also known as a multivisceral transplant, is performed when multiple abdominal organs fail and have to be replaced by healthy organs. This&nbsp;<strong>rare and invasive procedure&nbsp;</strong>is also a treatment option in patients with extensive thrombosis of the abdominal vessels or for certain tumours. This procedure is for some patients the only live-saving option.&nbsp;</p> <p>This type of multivisceral transplant in a toddler is incidentally also a first within&nbsp;<a href="https://www.eurotransplant.org/" target="_blank" rel="noreferrer noopener">Eurotransplant</a>, which included eight countries: Austria, Belgium, Croatia, Germany, Hungary, Luxemburg, the&nbsp; Netherlands and Slovenia.</p> <p>&nbsp;</p> </div> <div id="e7c3e493-d08a-4235-a264-dff5e25f9a74" class="block--text text"> <h2 id="complex-procedure">Complex procedure</h2> <p>A transplant where all abdominal organs are being replaced, requires&nbsp;<strong>intense collaboration</strong>&nbsp;between specialists of various disciplines and departments: transplant surgeons, specialised anaesthesiologists and intensivists, interventional radiologists, perfusionists,&nbsp;gastroenterology and hepatology specialists, peadiatricians and transplant coordinators and nurses.&nbsp;</p> <p>When a suitable donor presents itself, the first priority is to get this multidisciplinary team up and running at short notice.&nbsp;Then two surgical teams simultaneously operate on the donor, which is often found abroad, and the receiver in order to reduce the retention time. Especially intestines need to be moved very quickly from one body to the other. This type of invasive procedure also holds big risks for the patients cardiovascular and metabolic system, especially when removing the sick organs and restarting the blood circulation of the new organs after implantation. After the transplant the patient will be monitored for the rest of his life.&nbsp;</p> </div> <blockquote class="quote" id="we-mobilise-various-teams-and-specialists-at-very-short-notice-and-sometimes-in-the-middle-of-the-night"> <div class="quote__content "> <svg class="quote__quotemark" width="50" height="36" xmlns="http://www.w3.org/2000/svg"><path d="M10.976 13.09c6.034 0 10.926 5.13 10.926 11.455C21.902 30.872 17.01 36 10.976 36 4.94 36 .049 30.872.049 24.545L0 22.91C0 10.257 9.784 0 21.854 0v6.545c-4.17 0-8.09 1.703-11.038 4.793a16.413 16.413 0 0 0-1.553 1.893c.558-.092 1.13-.14 1.713-.14zm28.097 0C45.108 13.09 50 18.22 50 24.546 50 30.872 45.108 36 39.073 36c-6.034 0-10.927-5.128-10.927-11.455l-.048-1.636C28.098 10.257 37.882 0 49.95 0v6.545c-4.17 0-8.09 1.703-11.038 4.793a16.404 16.404 0 0 0-1.552 1.893c.558-.092 1.13-.14 1.712-.14z" fill="#007ACC" fill-rule="nonzero"/></svg> <div class="quote__text"> We mobilise various teams and specialists at very short notice and sometimes in the middle of the night </div> <img class="quote__img quote__img--no-crop" src="https://wmimages.uzleuven.be/styles/1d41396c1273794b4b4f4759cfde2dfc2f9128dd/2023-12/112754.jpg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjI0MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOnRydWV9fV0=&amp;sign=b43151ad529944e4c8dcd6b84cf7afa8bba3eb67ba094d9036c0edbd129b9e78" /> </div> </blockquote> <div id="6a97f49a-484e-46d7-8d42-605da5b524f3" class="block--text text"> <p><strong>Prof. dr. Jacques Pirenne</strong>, head of the abdominal transplant surgery department at UZ Leuven: &ldquo;The organisation of a multivisceral transplant is a challenge:&nbsp;We mobilise various teams and specialists at very short notice and sometimes in the middle of the night. We are therefore very pleased to announce that the young patient is doing well and is able to eat normally again.&rdquo;</p> </div> <div id="81098b7a-cf5f-41c8-9b03-c990d4f15943" class="block--text text"> <h2 id="multivisceral-transplants-at-uz-leuven">Multivisceral transplants at UZ Leuven</h2> <p>UZ Leuven already performed nine similar multivisceral transplants, eleven combined liver-pancreas-intestinal transplants (without the stomach) and nine isolated intestinal transplants in adults and children. Instestines are particularly susceptible to rejection, but the simultaneous transplant of the liver and the small intestine (as was the case for this young patient) and the standard application of a specially designed protocol improve the outcome. The 5 year survival rate of patient is 80%, similar to other organ transplants.</p> </div> <figure class="media is-large js-lightbox" id=""> <div class="media__wrapper"> <div class="media__controls"> <button class="fullscreen-btn js-lightbox-btn"> <svg class="flickity-button-icon is-expand" viewBox="0 0 32 32" aria-label="View full-screen" title="View full-screen"><path d="M15,20,7,28h5v4H0V20H4v5l8-8Zm5-5,8-8v5h4V0H20V4h5l-8,8Z"></path></svg> <svg class="flickity-button-icon is-inline" viewBox="0 0 32 32" aria-label="Exit full-screen" title="Exit full-screen"><path d="M32,3l-7,7h5v4H18V2h4V7l7-7ZM3,32l7-7v5h4V18H2v4H7L0,29Z"></path></svg> </button> </div> <div class="media__content"> <img class="media__img" src="https://wmimages.uzleuven.be/styles/bb8d67e3da164c4556ec65b16a74c7b3c5a6622b/2023-12/multiviscerale_transplantatie.jpg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6Imluc2lkZSIsIndpZHRoIjoxNDIwLCJoZWlnaHQiOjEwODAsIndpdGhvdXRFbmxhcmdlbWVudCI6dHJ1ZX19XQ==&amp;sign=6721ec3ff00fc8f071dc74f747277800197b766827c34f7b6da753fa8a0e1b9f" alt="" /> <figcaption class="media__caption"> <span class="media__caption__text"><p>漏 UZ Leuven</p> </span> </figcaption> </div> </div> </figure> <div class="cta bg-light-blue"> <div class="cta__content cta--align-image-right"> <div class="cta__wrapper"> <h2 class="cta__title heading-3"> </h2> <div class="cta__description text is-reset"> <p>UZ Leuven had by now become an international reference centre for the treatment of patients with intestinal failure and intestinal transplants. Six years ago, the Leuven Intestinal Failure and Transplantation Center (LIFT) was set up, a unique multidisciplinary evaluation and treatment centre for patients with intestinal failure. Under the supervision of prof. dr. Tim Vanuytsel (gastro-enterologist), prof. dr. Laurens Ceulemans and prof. dr. Jacques Pirenne (transplant surgeons) the centre stimulates Leuvense gastro-enterologists, abdominal surgeons and transplant surgeons to research ground-breaking treatment methods together.&nbsp;</p> </div> </div> </div> </div> <h2 class="" id="lift-members"> <span>LIFT members</span> </h2> <div class="attachment" id=""> <div class="attachment__icon"> <svg class="attachment__box" width="52" height="62" viewBox="0 0 52 62"><defs><filter x="-42.9%" y="-42.9%" width="185.7%" height="185.7%" filterUnits="objectBoundingBox" id="a"><feGaussianBlur stdDeviation="2" in="SourceGraphic"/></filter></defs><g fill="none" fill-rule="evenodd"><path fill="#E9F7FF" d="M0 2h35.013L50 17.003V62H0z"/><path fill="#ADDBF4" opacity=".75" filter="url(#a)" d="M48 15v1H34V2h1l3.584 9.584z" transform="translate(0 2)"/><path fill="#E9F7FF" d="M50 17H35V2z"/></g></svg> <span class="attachment__extension">PPTX</span> </div> <div class="attachment__content"> <a class="attachment__link" href="https://www.uzleuven.be/nl/media/39e0667c-4f18-4a3f-b60e-2702ac28bb3f/lift-leden.pptx" download target="_blank" rel="nofollow noreferrer">lift-leden.pptx</a> <div class="attachment__meta"> PPTX - 335.87 Kb</div> </div> </div> <div class="message is-default is-year-report"> <div class="message__content"> <h3 class="message__title">This article is part of the Annual report 2023</h3> <ul class="list is-styled"> <li><a href="/en/annual-reports/annual-report-2023/news/uz-leuven-helps-build-climate-neutral-leuven">UZ Leuven helps build a climate-neutral Leuven</a></li> <li><a href="/en/annual-reports/annual-report-2023/news/uz-leuven-recognised-first-forensic-medical-institute-our">UZ Leuven recognised as the first forensic medical institute in our country</a></li> <li><a href="/en/annual-reports/annual-report-2023/news/coloured-arrows-gasthuisberg-campus-make-way-modern-street">Coloured arrows at the Gasthuisberg campus make way for modern street plan</a></li> </ul> <a href="/en/annual-reports/2023" class="link-btn"> <svg class="link-btn__icon icon is-ghost is-small" width="18" height="18"><use xlink:href="#arrow-right"></use></svg> <span class="link-btn__text"><span class="link-btn__text__content">View all articles from the Annual report 2023</span></span> </a> </div> </div> <h2 class="heading-2" id="related">Related</h2> <div class="message is-accent is-link" href="/en/news/first-combined-genetic-and-epigenetic-test-ensures-quicker-diagnosis-rare-diseases"> <div class="message__content"> <div class="message__meta meta">More about "Rare diseases"</div> <h3 class="message__title heading-3">First combined genetic and epigenetic test ensures quicker diagnosis of rare diseases</h3> <div class="messsage__date meta">15 January 2025</div> <div class="message__text">Researchers of the centre for human genetics (CME) developed a new diagnostic method for detecting both genetic and epigenetic anomalies with one single analysis. The technique improves the diagnosis of rare developmental disorders and will soon become standard clinical practice.</div> <a class="link-btn" href="/en/news/first-combined-genetic-and-epigenetic-test-ensures-quicker-diagnosis-rare-diseases" target="" rel=""> <svg class="link-btn__icon icon is-ghost is-small" width="18" height="18"><use xlink:href="#arrow-right"></use></svg> <span class="link-btn__text"><span class="link-btn__text__content">More info</span></span> </a> </div> </div> <div class="message is-accent is-link" href="/en/news/belgium-has-been-waiting-20-years-national-recognition-its-centres-expertise-rare-diseases"> <div class="message__content"> <div class="message__meta meta">More about "Rare diseases"</div> <h3 class="message__title heading-3">Belgium has been waiting for 20 years for national recognition of its centres of expertise for rare diseases</h3> <div class="messsage__date meta">7 November 2024</div> <div class="message__text">Belgian doctors, hospitals and patients are collectively sounding the alarm. With a new Flemish and federal government in the making, they are calling for the Rare Diseases Plan to be put high on the agenda again. Belgium is one of the few European countries that does not have national reference centres for rare diseases. 鈥淭he patient bears the brunt of this."</div> <a class="link-btn" href="/en/news/belgium-has-been-waiting-20-years-national-recognition-its-centres-expertise-rare-diseases" target="" rel=""> <svg class="link-btn__icon icon is-ghost is-small" width="18" height="18"><use xlink:href="#arrow-right"></use></svg> <span class="link-btn__text"><span class="link-btn__text__content">More info</span></span> </a> </div> </div> <div class="message is-accent is-link" href="/en/news/first-abdominal-wall-transplant-belgium"> <div class="message__content"> <div class="message__meta meta">More about "Darmtransplantatie"</div> <h3 class="message__title heading-3">First abdominal wall transplant in Belgium</h3> <div class="messsage__date meta">19 January 2022</div> <div class="message__text">At UZ Leuven, two intestine transplant patients were succesfully given a new abdominal wall. This procedure has only been done about 50 times across the world.</div> <a class="link-btn" href="/en/news/first-abdominal-wall-transplant-belgium" target="" rel=""> <svg class="link-btn__icon icon is-ghost is-small" width="18" height="18"><use xlink:href="#arrow-right"></use></svg> <span class="link-btn__text"><span class="link-btn__text__content">More info</span></span> </a> </div> </div> <div id="feedback" data-i18n="{&quot;formSource&quot;:&quot;node:47e524c5-105e-4c1d-bb20-b05a92122cdd&quot;,&quot;done&quot;:&quot;Thanks for your feedback.&quot;,&quot;title&quot;:&quot;Remarks about this page?&quot;,&quot;button_yes&quot;:&quot;Let us know&quot;,&quot;email_label&quot;:&quot;Email&quot;,&quot;feedback_label&quot;:&quot;Feedback&quot;,&quot;submit_label&quot;:&quot;Submit feedback&quot;,&quot;error_messages&quot;:{&quot;required&quot;:&quot;This field is required.&quot;,&quot;email&quot;:&quot;Invalid email.&quot;,&quot;min_char&quot;:&quot;At least 20 characters are required.&quot;},&quot;description&quot;:&quot;For personal medical enquiries, you have to make an appointment with a physician.&quot;}"></div> <div class="meta"> Last edit: 12 january 2024 </div> </div> </article> </div> </main> <footer> <div class="footer"> <div class="footer__row"> <div class="footer__inside"> <div class="footer__columns"> <div class="footer__column"> <h4 class="footer__heading heading-3">Contact</h4> <p><a href="tel:+3216332211" target="_blank" rel="noreferrer noopener">+32 16 33 22 11</a></p> <p>Herestraat 49, 3000 Leuven, Belgium</p> <p><a href="/en/node/13495">All&nbsp;contact information</a></p> <div class="social-list"> <span class="social-list__title">Also find us on:</span> <ul class="list horizontal-list is-small"> <li> <a class="footer__social icon--facebook" href="https://www.facebook.com/uzleuven" target="_blank" rel="noopener noreferrer"> <svg width="24" height="24"><use xlink:href="#facebook"></use></svg> <span class="visually-hidden">Facebook</span> </a> </li> <li> <a class="footer__social icon--twitter" href="https://twitter.com/uzleuven" target="_blank" rel="noopener noreferrer"> <svg width="24" height="24"><use xlink:href="#twitter"></use></svg> <span class="visually-hidden">Twitter</span> </a> </li> <li> <a class="footer__social icon--linkedin" href="https://www.linkedin.com/company/uz-leuven" target="_blank" rel="noopener noreferrer"> <svg width="24" height="24"><use xlink:href="#linkedin"></use></svg> <span class="visually-hidden">LinkedIn</span> </a> </li> </ul> </div> </div> <div class="footer__column"> <h4 class="footer__heading heading-3"> <a class="heading-link" href="/en/consultation-and-admission"><span class="heading-link__text">Consultation and admission</span></a> </h4> <ul class="list"> <li> <a href="/en/consultation-and-admission/consultation-and-function-tests">Consultation</a> </li> <li> <a href="/en/consultation-and-admission/admission">Admission</a> </li> <li> <a href="/en/visits">Visiting hours</a> </li> <li> <a href="/en/greeting-card">Send a greeting card</a> </li> </ul> </div> <div class="footer__column"> <h4 class="footer__heading heading-3"> <a class="heading-link" href="/en/about-us"><span class="heading-link__text">About UZ Leuven</span></a> </h4> <ul class="list"> <li> <a href="/en/news-and-calendar">News and publications</a> </li> <li> <a href="/en/press-and-media">For press and media</a> </li> </ul> </div> </div> </div> </div> <div class="footer__row"> <div class="footer__inside"> <div class="footer__logos footer__columns"></div> </div> </div> </div> <div class="closure"> <div class="closure__inside"> <div class="closure__content"> <ul class="list horizontal-list is-nav closure__links" id="closure"> <li class="closure__item"><a class="closure__link" href="/en/cookie-policy">Cookie policy</a></li> <li class="closure__item"><a class="closure__link" href="/en/privacy-and-your-patient-record">Privacy</a></li> </ul> </div> <div class="closure__wieni"> <a class="wieni" href="https://www.wieni.be" target="_blank" title="site by wieni" rel="noopener noreferrer"> <svg class="wieni__logo" width="61" height="22"><use xlink:href="#wieni"></use></svg> </a> </div> </div> </div> </footer> </div> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"en\/","currentPath":"node\/20954","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"wmcustom_urls":{"search":"\/en\/search"},"analytics":{"nodeType":"Nieuws","isMedischeDienst":0},"outdatedBrowser":{"title":"Your browser is out-of-date","message":"\u003Cp\u003EIt seems you\u0027re using an outdated version of browser-name. 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