Smallpox

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defer src="https://connect.facebook.net/en_US/sdk.js#xfbml=1&version=v3.2"></script> <article class="sf-detail-body-container sf-detail-body-wrapper health-topic--detail dynamic-content dynamic-content__article"> <header class="dynamic-content__header dynamic-content__container"> <div class="sf-header-image dynamic-content__image dynamic-content__image" data-url=""> <div class="inner"> <a class="magnific-popup" href="https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-000731-orig.tmb-1920v.jpg?sfvrsn=a761f1a2_9 1920w" title=" WHO /Isao Arita The WHO smallpox eradication campaign was launched in its intensified form in 1967, and in four years had wiped out smallpox in Latin America. Four more years toppled the disease's last bastion in Asia. The multi-national teams closed in on Somalia, scene of "the last stand". The eradication of smallpox from the world was certified by the Global Commission, an independent panel of scientists drawn from 19 nations, in December 1979 at WHO Headquarters, Geneva."> <img sizes="(max-width: 479px) 280px, (max-width: 549px) 440px, (max-width: 768px) 660px, (max-width: 1366px) 1024px, 1920px" srcset="https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-000731-orig.tmb-479v.jpg?sfvrsn=a761f1a2_9 479w, https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-000731-orig.tmb-549v.jpg?sfvrsn=a761f1a2_9 549w, https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-000731-orig.tmb-768v.jpg?sfvrsn=a761f1a2_9 768w, https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-000731-orig.tmb-1024v.jpg?sfvrsn=a761f1a2_9 1024w, https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-000731-orig.tmb-1366v.jpg?sfvrsn=a761f1a2_9 1366w, https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-000731-orig.tmb-1920v.jpg?sfvrsn=a761f1a2_9 1920w" class="single-image" alt="Smallpox" /> </a> </div> <div class="sf-image-credit"> <div class="sf-image-credit__content"> <div class="sf-image-credit__inner"> WHO /Isao Arita <br />The WHO smallpox eradication campaign was launched in its intensified form in 1967, and in four years had wiped out smallpox in Latin America. Four more years toppled the disease's last bastion in Asia. The multi-national teams closed in on Somalia, scene of "the last stand". The eradication of smallpox from the world was certified by the Global Commission, an independent panel of scientists drawn from 19 nations, in December 1979 at WHO Headquarters, Geneva. </div> </div> <div class="sf-image-credit__label"> <span class="sf-image-credit__copyright">©</span> <span class="sf-image-credit__text">Credits </span> <i class="icon plus-icon"></i> </div> </div> <script> var imageCreditClass = document.getElementsByClassName("sf-image-credit"); var preventFunction = function () { event.preventDefault() }; for (var i = 0; i < imageCreditClass.length; i++) { imageCreditClass[i].addEventListener('click', preventFunction);; } </script> </div> <div class="dynamic-content__title"> <h1 class="dynamic-content__title-text">Smallpox</h1> </div> </header> <section class="dynamic-content__section dynamic-content__container"> <div class="row"> <div class="col-md-7"> <div class="dynamic-content__section-content"> <div class="sf_cols tabWidget health-topic_tabWidget"> <div class="sf_colsOut flex-clear" data-placeholder-label="Tab wrapper"> <div class="ul-tabs--wrapper"> <ul class="tabs"></ul> </div> <div class="sf_colsIn single-tabContent"> <div class="sf_cols singleTabWrapper"> <div class="sf_colsOut tabHeaderWrapper" data-sf-element="Tab header" data-placeholder-label="Tab header"> <div class="sf_colsIn tabHeaderText"> <div class="sf-content-block content-block"> Overview </div> </div> </div> <div class="sf_colsOut tabContent" data-sf-element="Tab contents" data-placeholder-label="Tab contents"> <div class="sf_colsIn"> <p>Smallpox is an acute contagious disease caused by the variola virus, a member of the orthopoxvirus family. It was one of the most devastating diseases known to humanity and caused millions of deaths before it was eradicated. It is believed to have existed for at least 3000 years.  </p><p>The smallpox vaccine, created by Edward Jenner in 1796, was the first successful vaccine to be developed. He observed that milkmaids who previously had caught cowpox did not catch smallpox and showed that a similar inoculation could be used to prevent smallpox in other people.</p><p>The World Health Organization launched an intensified plan to eradicate smallpox in 1967. Widespread immunization and surveillance were conducted around the world for several years. The last known natural case was in Somalia in 1977. In 1980 WHO declared smallpox eradicated – the only infectious disease to achieve this distinction. This remains among the most notable and profound public health successes in history.</p><p> </p> </div> </div> </div> <div class="sf_cols singleTabWrapper"> <div class="sf_colsOut tabHeaderWrapper" data-sf-element="Tab header" data-placeholder-label="Tab header"> <div class="sf_colsIn tabHeaderText"> <div class="sf-content-block content-block"> Symptoms </div> </div> </div> <div class="sf_colsOut tabContent" data-sf-element="Tab contents" data-placeholder-label="Tab contents"> <div class="sf_colsIn"> <p>Early symptoms of smallpox include high fever, fatigue and severe back pain, and less often, abdominal pain and vomiting. Two to 3 days later the virus produces a characteristic rash with bumps full of a clear liquid, which later fill with pus and finally develop a crust that dries and falls off. The rash begins on the face and hands, then spreads to the rest of the body. Lesions develop in the mucous membranes of the nose and mouth and ulcerate soon after formation. </p><p>Smallpox is transmitted from person to person via infective droplets during close contact with infected people who have symptoms of the disease, or in some cases through contaminated clothing and bedding. It has an incubation period of 7–17 days after exposure and only becomes infectious once a fever develops. People remain infectious until the last scabs fall off. </p><p>Smallpox was fatal in up to 30% of cases.</p><p><a href="/publications/m/item/who-smallpox-recognition-card">WHO smallpox recognition card</a></p><p></p> </div> </div> </div> <div class="sf_cols singleTabWrapper"> <div class="sf_colsOut tabHeaderWrapper" data-sf-element="Tab header" data-placeholder-label="Tab header"> <div class="sf_colsIn tabHeaderText"> <div class="sf-content-block content-block"> WHO response </div> </div> </div> <div class="sf_colsOut tabContent" data-sf-element="Tab contents" data-placeholder-label="Tab contents"> <div class="sf_colsIn"> <p>The period since eradication has been defined by a lengthy and complex debate focussed on the destruction of the last remaining stocks of live variola virus. In 1996, at the 49th World Health Assembly, Member States decided to have this stock destroyed in June 1999, and only to allow small samples to be kept for research purposes at two designated secure laboratories – one in the United States and one in the Russian Federation. Temporary retention of the existing stocks of variola virus are used for further essential research, which is overseen by the Advisory Committee for Variola Virus Research. This group meets on an annual basis.</p><p><strong></strong><strong></strong><strong>The WHO Smallpox Secretariat</strong> based in WHO Headquarters coordinates all smallpox eradication-related and post-eradication activities. These include overseeing permitted<a href="/activities/research-using-live-variola-virus"> </a><a href="/activities/research-using-live-variola-virus"></a>research with live variola virus for the development of countermeasures such as vaccine and antivirals. Since the eradication era, safer vaccines and specific treatments have been developed for smallpox and related diseases such as <a href="/health-topics/mpox">monkeypox</a>. The Secretariat is also responsible for emergency preparedness and manages a <a href="/groups/global-advisory-committee-on-vaccine-safety/topics/smallpox-vaccines">smallpox vaccine</a> emergency stockpile in the unlikely event that the disease re-emerges. The Secretariat manages the <a href="/activities/variola-virus-repository-safety-inspections">biosafety and biosecurity inspections</a> of the authorized variola virus repositories as mandated by the World Health Assembly, and ensures <a href="/emergencies/situations/smallpox/world-health-assembly-resolutions-and-reports">annual reporting</a> to WHO Governing Bodies. The Smallpox Secretariat supports WHO Archives in preserving the global history of smallpox and documenting the lessons learned from successful eradication of smallpox.<o:p></o:p></p><p> </p><div data-class="more-content"><div data-class="more-content-inner"><p>The <strong>WHO Smallpox Secretariat's </strong>current roles and responsibilities include: <o:p></o:p></p><p><strong style="background-color:transparent;text-align:inherit;text-transform:inherit;white-space:inherit;word-spacing:normal;caret-color:auto;">Variola virus research and development of countermeasures</strong> <o:p></o:p></p><ul><li>organizing annual meetings of the <a href="/groups/strategic-advisory-group-of-experts-on-immunization/working-groups/cholera-(november-2015---august-2017)">WHO Advisory Committee on Variola Virus Research (ACVVR)</a> </li><li>coordinating review of <a href="/activities/improving-treatment-for-snakebite-patients"></a><a href="/activities/improving-treatment-for-snakebite-patients">research </a>proposals for work with variola virus through the ACVVR </li><li>managing relationships with the two variola virus repositories (which are also WHO Collaborating Centres) </li><li>recording, processing and monitoring requests from researchers for variola virus DNA from the 2 repositories under specific rules </li><li>conducting biennial <a href="/activities/variola-virus-repository-safety-inspections">biosafety and biosecurity inspections</a> of the 2 global variola virus repositories </li><li>developing normative guidance regarding <a href="/publications/i/item/10665-241232">research on variola virus DNA</a> and related matters</li></ul><p> </p><p><strong>Emergency preparedness and response</strong></p><ul><li><span style="background-color:transparent;font-family:inherit;text-align:inherit;text-transform:inherit;white-space:inherit;word-spacing:normal;caret-color:auto;font-size:inherit;">coordinating and preparing normative guidance on development and use of medical countermeasures for orthopoxviruses</span></li><li>developing preparedness and response strategies, and tools to implement preparedness measures </li><li>maintaining and managing the <a href="/groups/global-advisory-committee-on-vaccine-safety/topics/smallpox-vaccines">smallpox global vaccine stockpile</a> </li><li>coordinating development of a laboratory network for orthopoxvirus detection and diagnostics </li><li>developing normative guidance and response strategies for human <a href="/westernpacific/health-topics/mpox">monkeypox</a> and other orthopoxviruses </li><li>supporting capacity-building and developing training materials </li><li>contributing to global health security initiatives</li></ul><p><strong>Preserving global smallpox history</strong></p><ul><li>overseeing the <a href="/archives/fonds">Smallpox Eradication Programme archives</a> in collaboration with <a href="/archives">WHO Archives</a> and the <a href="/library">WHO Library</a> </li><li>leading on policy discussions and <a href="https://www.youtube.com/watch?v=freX6WB8Cag&t=7s" data-sf-ec-immutable="">commemorative events</a> regarding smallpox eradication </li><li>reporting annually to the<a href="/about/governance/executive-board"> WHO Executive Board</a> and the <a href="/about/governance/world-health-assembly">World Health Assembly</a></li></ul><p>The Secretariat also <strong>mobilizes and manages funding</strong> for these activities and for ad hoc events as required such as technical consultations and training. </p></div></div><div data-class="more-button"><div data-class="more-button-label" data-close="" data-open=""><text>Show less</text> <text>Show more</text></div></div><p> </p><p> </p> </div> </div> </div> </div> </div> </div> </div> </div> <div class="col-md-4 col-md-push-1"> <div class="dynamic-content__sidebar"> <div id="dynamic-content__accordion" class="dynamic-content__accordion sf-accordion"> <div class="sf-accordion__panel"><div class="sf-accordion__title"><a href="#" 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class="sf-accordion__content"><ul><li class=""><a href="#"><a href="/groups/who-advisory-committee-on-variola-virus-research/meeting-documents">WHO Advisory Committee on Variola Virus Research meeting reports</a></a></li><li class=""><a href="#"><a href="/emergencies/situations/smallpox/committee-on-orthopoxvirus-infections-meeting-reports">Committee on Orthopoxvirus Infections meeting reports</a></a></li><li class=""><a href="#"><a href="/emergencies/situations/smallpox/biosafety-inspection-reports">Biosafety inspection reports</a></a></li><li class=""><a href="#"><a href="E6F5A7F7-67F7-49F9-BFCF-64AC47FA8338"></a></a></li><li class=""><a href="#"><a href="/publications/i/item/the-independent-advisory-group-on-public-health-implications-of-synthetic-biology-technology-related-to-smallpox">The Independent Advisory Group on Public Health Implications of Synthetic Biology Technology Related to Smallpox</a></a></li><li class=""><a href="#"><a href="/emergencies/situations/smallpox/advisory-group-of-independent-experts-(agies)-to-review-the-smallpox-research-programme">Advisory group of Independent Experts (AGIES) to review the smallpox research programme</a> </a></li></ul></div></div></li><div class="sf-accordion__panel"><div class="sf-accordion__title"><a href="#" class="sf-accordion__trigger-panel">Post-eradication of smallpox <span class="sf-accordion__icon"></span></a></div><div class="sf-accordion__content"><ul><li class=""><a href="#"><a href="/news-room/feature-stories/detail/post-eradication">Read more on post-eradication</a> </a></li></ul></div></div></li><div class="sf-accordion__panel"><div class="sf-accordion__title"><a href="#" class="sf-accordion__trigger-panel">Preparedness and response <span class="sf-accordion__icon"></span></a></div><div class="sf-accordion__content"><ul><li class=""><a href="#"><a data-sf-ec-immutable="" href="https://www.who.int/csr/disease/smallpox/preparedness/en/" target="_blank"></a></a></li><li class=""><a href="#"><a href="/news-room/feature-stories/detail/preparedness-in-the-event-of-a-smallpox-outbreak">Preparedness </a>in case of any kind of smallpox event requires national and international attention</a></li><li class=""><a href="#"><a href="/publications/m/item/case-definition-for-notification-of-smallpox-under-the-ihr-(2005)">Case definition for smallpox</a> </a></li><li class=""><a href="#"><a href="/publications/m/item/smallpox-clinical-diagnosis">Clinical diagnosis</a> </a></li><li class=""><a href="#"><a href="/publications/m/item/smallpox-diagnostics-laboratory-network">Diagnostics</a> </a></li><li class=""><a href="#"><a href="/news-room/feature-stories/detail/smallpox-vaccines">Vaccines</a> </a></li></ul></div></div></li><div class="sf-accordion__panel"><div class="sf-accordion__title"><a href="#" class="sf-accordion__trigger-panel">WHO teams <span class="sf-accordion__icon"></span></a></div><div class="sf-accordion__content"><ul><li class=""><a href="#"><a href="/teams/environment-climate-change-and-health/emergencies/disease-outbreaks">Communicable Diseases</a> </a></li></ul></div></div></li><div class="sf-accordion__panel"><div class="sf-accordion__title"><a href="#" class="sf-accordion__trigger-panel">Archived disease outbreak news<p data-sf-tooltip="input-title" sftextdirection="" role="input" aria-label="Title" data-placeholder="Title"> <span class="sf-accordion__icon"></span></a></div><div class="sf-accordion__content"><ul><li class=""><a href="#"><a href="/emergencies/disease-outbreak-news/item/2000_06_20e-en">2000 - Accidental exposure to smallpox vaccine in the Russian Federation</a> </a></li></ul></div></div></li> </div> </div> </div> </div> <div class="row"> <div class="col-md-7"> <div id="statistics-slider-6fef08c4-65db-4cc8-997b-327ab6a5aca9" class="statistics-slider "> <div class="statistics-slide"> <figure class="statistics-slide__figure"> <div class="Map"></div> </figure> <div class="statistics-slide__text-box"> <h2 class="text-box__heading">Eradicated 1980</h2> <h3 class="text-box__subheading">a global achievement</h3> <p class="text-box__content">For at least 3000 years smallpox had devastated humanity.</p> </div> </div> </div> <script> $(function () { var gallery = $('.statistics-slider .statistics-slide'); if (gallery.children().length > 1) { $('#statistics-slider-6fef08c4-65db-4cc8-997b-327ab6a5aca9').slick({ arrows: false, dots: true, infinite: true }); } }); </script> </div> </div> </section> </article> <script type='text/javascript' src='/ResourcePackages/WHO/assets/dist/scripts/accordion-list.min.js?v=14.0.7729.18497'></script> <script type="text/javascript"> (function () { new AccordionJS('dynamic-content__accordion'); })(); function buildMagnificThumbnail() { let imgUrl = $('.magnific-popup').attr('href'); if ($(window).width() < 480) { imgUrl = imgUrl.replace(/1920/g, '479'); } else if ($(window).width() >= 480 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data-placeholder-label="Column 1"> <div class="section-heading"> <p>Our work</p> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_C298_Col00" class="sf_colsIn col-md-6" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div class="sf-slider-related ui-slider--multiple"> <div class="sf-slick-slider slick-slider"> <div class="list-view horizontal-list sf-visible"> <div class="list-view--item horizontal-list-item"> <a href="https://www.who.int/activities/variola-virus-repository-safety-inspections" class="link-container" aria-label="Variola virus repository safety inspections" role="link"> <div class="thumb"> <div class="background-image background-image--small" data-image="/images/default-source/health-topics/smallpox/who-a-011153-orig.tmb-768v.jpg?Culture=en&sfvrsn=21f65ce6_6" style="background-image: url('/images/default-source/health-topics/smallpox/who-a-011153-orig.tmb-549v.jpg?Culture=en&sfvrsn=21f65ce6_6')"> </div> </div> <div class="info"> <div class="date"> </div> <p class="heading text-underline">Variola virus repository safety inspections</p> </div> </a> </div> <div class="list-view--item horizontal-list-item"> <a href="https://www.who.int/activities/research-using-live-variola-virus" class="link-container" aria-label="Research using live variola virus" role="link"> <div class="thumb"> <div class="background-image background-image--small" data-image="https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-010997-orig.tmb-768v.jpg?sfvrsn=d2c82767_6" style="background-image: url('https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-010997-orig.tmb-549v.jpg?sfvrsn=d2c82767_6')"> </div> </div> <div class="info"> <div class="date"> </div> <p class="heading text-underline">Research using live variola virus</p> </div> </a> </div> </div> </div> </div> </div> <div id="PageContent_C298_Col01" class="sf_colsIn col-md-6" data-sf-element="Column 2" data-placeholder-label="Column 2"> <div class="list-view vertical-list"> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/news-room/articles-detail/orthopoxvirus-laboratory-survey" class="link-container" aria-label="Orthopoxvirus laboratory survey" role="link"> <div class="info"> <div class="date"> <span class="timestamp">10 November 2021</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">Case study</div> </div> </div> <p class="heading text-underline">Orthopoxvirus laboratory survey</p> </div> </a> </div> </div> </div> </div> <div class="section-heading"> <p>Smallpox eradication</p> </div> <div class="list-view horizontal-list matching-height"> <div class="list-view--item horizontal-list-item matching-height--item"> <a href="https://www.who.int/news-room/feature-stories/detail/preparedness-in-the-event-of-a-smallpox-outbreak" class="link-container" aria-label="Preparedness in the event of a smallpox outbreak" role="link"> <div class="thumb"> <div class="background-image background-image--small" data-image="https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-000725.tmb-768v.png?sfvrsn=d5667187_2" style="background-image: url('https://cdn.who.int/media/images/default-source/health-topics/smallpox/who-a-000725.tmb-549v.png?sfvrsn=d5667187_2')"></div> </div> <div class="info"> <div class="date"> <span class="timestamp">1 December 2017</span> </div> <p class="heading text-underline">Preparedness in the event of a smallpox outbreak</p> <div class="description"> <p></p> </div> </div> </a> </div> <div class="list-view--item horizontal-list-item matching-height--item"> <a href="https://www.who.int/news-room/feature-stories/detail/post-eradication" class="link-container" aria-label="Post-eradication" role="link"> <div class="thumb"> <div class="background-image background-image--small" data-image="/images/default-source/health-topics/smallpox/last-case-02.tmb-768v.jpg?Culture=en&sfvrsn=ff255b65_2" style="background-image: url('/images/default-source/health-topics/smallpox/last-case-02.tmb-549v.jpg?Culture=en&sfvrsn=ff255b65_2')"></div> </div> <div class="info"> <div class="date"> <span class="timestamp">28 June 2016</span> </div> <p class="heading text-underline">Post-eradication</p> <div class="description"> <p></p> </div> </div> </a> </div> <div class="list-view--item horizontal-list-item matching-height--item"> <a href="https://www.who.int/news-room/feature-stories/detail/smallpox-vaccines" class="link-container" aria-label="Smallpox vaccines" role="link"> <div class="thumb"> <div class="background-image background-image--small" data-image="/images/default-source/departments/immunization-ivb/images/smallpox-eradication-campaign-south-america.tmb-768v.jpg?Culture=en&sfvrsn=869285fa_1" style="background-image: url('/images/default-source/departments/immunization-ivb/images/smallpox-eradication-campaign-south-america.tmb-549v.jpg?Culture=en&sfvrsn=869285fa_1')"></div> </div> <div class="info"> <div class="date"> <span class="timestamp">31 May 2016</span> </div> <p class="heading text-underline">Smallpox vaccines</p> <div class="description"> <p></p> </div> </div> </a> </div> <div class="list-view--item horizontal-list-item matching-height--item"> <a href="https://www.who.int/news-room/feature-stories/detail/synthetic-biology-technologies" class="link-container" aria-label="Synthetic biology technologies" role="link"> <div class="thumb"> <div class="background-image background-image--small" data-image="/images/default-source/health-topics/smallpox/who-a-000735-orig.tmb-768v.jpg?Culture=en&sfvrsn=d9b7146b_6" style="background-image: url('/images/default-source/health-topics/smallpox/who-a-000735-orig.tmb-549v.jpg?Culture=en&sfvrsn=d9b7146b_6')"></div> </div> <div class="info"> <div class="date"> <span class="timestamp">1 June 2015</span> </div> <p class="heading text-underline">Synthetic biology technologies</p> <div class="description"> <p></p> </div> </div> </a> </div> </div><div class="row" data-sf-element="Row"> <div id="PageContent_C301_Col00" class="sf_colsIn col-md-6" data-sf-element="Column 1" data-placeholder-label="Column 1"><div class="row" data-sf-element="Row"> <div id="PageContent_C300_Col00" class="sf_colsIn col-md-6" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div class="list-view vertical-list"> <div class="list-view--item vertical-list-item vertical-list-item--hightlight-image"> <a href="https://www.who.int/news-room/feature-stories/detail/the-smallpox-eradication-programme---sep-(1966-1980)" class="link-container" aria-label="Smallpox Eradication Programme - SEP (1966-1980)" role="link"> <div class="thumb"> <div class="background-image" data-image="/images/default-source/health-topics/smallpox/who-a-027548468c78fc8c2f4734868a8c0768106330.tmb-479v.png?Culture=en&sfvrsn=d398e43d_2" style="background-image: url('/images/default-source/health-topics/smallpox/who-a-027548468c78fc8c2f4734868a8c0768106330.tmb-479v.png?Culture=en&sfvrsn=d398e43d_2')"></div> </div> <div class="info"> <div class="date"> <span class="timestamp">1 May 2010</span> </div> <p class="heading text-underline">Smallpox Eradication Programme - SEP (1966-1980)</p> </div> </a> </div> </div> </div> <div id="PageContent_C300_Col01" class="sf_colsIn col-md-6" data-sf-element="Column 2" data-placeholder-label="Column 2"> <div class="card--list" role="article"> <div class="card-item__container"> <figure class="card-item__figure"> <a href="/archives/fonds" target="_self" > <img src="https://cdn.who.int/media/images/default-source/health-topics/smallpox/poster-06.jpg?sfvrsn=af50d2b9_1" title="POSTER_06" alt=""> </a> </figure> <div class="card-item__body"> <div class="card-item__header"> <a href="/archives/fonds" target="_self"> <h3 id="09c8245a454e4eb58bd8c7eaa7fe2ddb" class="card-item-item__title">Archives of the smallpox eradication programme</h3> </a> </div> <div class="card-item__actions"> </div> </div> </div> </div> </div> </div> </div> <div id="PageContent_C301_Col01" class="sf_colsIn col-md-6" data-sf-element="Column 2" data-placeholder-label="Column 2"> </div> </div> </div> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_C264_Col00" class="sf_colsIn col-md-12" data-sf-element="Column 1" data-placeholder-label="Column 1"><div id="PageContent_C292_Col00" class="sf_colsIn container" data-sf-element="Container" data-placeholder-label="Container"> </div> <div class="section-heading"> <h2>News</h2> <a href="https://www.who.int/news?healthtopics=4e223afd-0114-4f4d-be56-b8c5f968f7a0&publishingoffices=aeebab07-3d0c-4a24-b6ef-7c11b7139e43">All →</a> </div> <div class="sf-slider-related ui-slider--multiple"> <div class="sf-slick-slider slick-slider"> <div class="list-view horizontal-list sf-visible"> <div class="list-view--item horizontal-list-item"> <a href="https://www.who.int/news/item/08-05-2020-commemorating-smallpox-eradication-a-legacy-of-hope-for-covid-19-and-other-diseases" class="link-container" aria-label="Commemorating Smallpox Eradication – a legacy of hope, for COVID-19 and other diseases" role="link"> <div class="thumb"> <div class="background-image background-image--small" data-image="https://cdn.who.int/media/images/default-source/health-topics/smallpox/foto-es.tmb-768v.png?sfvrsn=fbc6909b_13" style="background-image: url('https://cdn.who.int/media/images/default-source/health-topics/smallpox/foto-es.tmb-549v.png?sfvrsn=fbc6909b_13')"> </div> </div> <div class="info"> <div class="date"> <span class="timestamp">8 May 2020</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">News release</div> </div> </div> <p class="heading text-underline">Commemorating Smallpox Eradication – a legacy of hope, for COVID-19 and other diseases</p> </div> </a> </div> <div class="list-view--item horizontal-list-item"> <a href="https://www.who.int/news/item/08-05-2020-un-issues-a-stamp-to-commemorate-the-40th-anniversary-of-the-eradication-of-smallpox" class="link-container" aria-label="UN issues a stamp to commemorate the 40th anniversary of the eradication of smallpox" role="link"> <div class="thumb"> <div class="background-image background-image--small" data-image="/images/default-source/default-album/smallpox-sm-fdc-2020-2.tmb-768v.jpg?Culture=en&sfvrsn=769b2e24_1" style="background-image: url('/images/default-source/default-album/smallpox-sm-fdc-2020-2.tmb-549v.jpg?Culture=en&sfvrsn=769b2e24_1')"> </div> </div> <div class="info"> <div class="date"> <span class="timestamp">8 May 2020</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">News release</div> </div> </div> <p class="heading text-underline">UN issues a stamp to commemorate the 40th anniversary of the eradication of smallpox</p> </div> </a> </div> <div class="list-view--item horizontal-list-item"> <a href="https://www.who.int/news/item/13-12-2019-who-commemorates-the-40th-anniversary-of-smallpox-eradication" class="link-container" aria-label="WHO commemorates the 40th anniversary of smallpox eradication" role="link"> <div class="thumb"> <div class="background-image background-image--small" data-image="https://cdn.who.int/media/images/default-source/imported/small-pox-eradication.tmb-768v.jpg?sfvrsn=28a6e1a_3" style="background-image: url('https://cdn.who.int/media/images/default-source/imported/small-pox-eradication.tmb-549v.jpg?sfvrsn=28a6e1a_3')"> </div> </div> <div class="info"> <div class="date"> <span class="timestamp">13 December 2019</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">News release</div> </div> </div> <p class="heading text-underline">WHO commemorates the 40th anniversary of smallpox eradication</p> </div> </a> </div> <div class="list-view--item horizontal-list-item"> <a href="https://www.who.int/news/item/17-05-2010-statue-commemorates-smallpox-eradication" class="link-container" aria-label="Statue commemorates smallpox eradication" role="link"> <div class="thumb"> <div class="background-image background-image--small" data-image="https://cdn.who.int/media/images/default-source/dr-tedros-one-year-together/smallpox-statue-at-who-headquarters-in-geneva-switzerland.tmb-768v.jpg?sfvrsn=3086d8b3_12" style="background-image: url('https://cdn.who.int/media/images/default-source/dr-tedros-one-year-together/smallpox-statue-at-who-headquarters-in-geneva-switzerland.tmb-549v.jpg?sfvrsn=3086d8b3_12')"> </div> </div> <div class="info"> <div class="date"> <span class="timestamp">17 May 2010</span> <div class="sf-tags-list"> <div class="sf-tags-list-item">Note for Media</div> </div> </div> <p class="heading text-underline">Statue commemorates smallpox eradication</p> </div> </a> </div> </div> </div> </div> </div> </div> <div class="section-heading"> <p>Publications</p> <a href="https://www.who.int/publications/i?healthtopics=4e223afd-0114-4f4d-be56-b8c5f968f7a0">All →</a> </div> <div class="sf-publications"> <div class="sf-publications-list sf-publications-list__horizontal row"> <div class="sf-publications-item list-item col-sm-3"> <div class="sf-publications-item__container"> <figure class="sf-publications-item__figure"> <img src="https://iris.who.int/bitstream/handle/10665/377616/WHO-WHE-EPP-2024.1-eng.pdf.jpg?sequence=4" alt="WHO Inspection report of the variola virus repository at CDC, 2-6 May 2022" /> </figure> <div class="sf-publications-item__body"> <div class="sf-publications-item__header"> <div class="sf-publications-item__date"> <span>20 June 2024</span> </div> <a href="https://www.who.int/publications/i/item/WHO-WHE-EPP-2024-1"> <h3 class="sf-publications-item__title">WHO Inspection report of the variola virus repository at CDC, 2-6 May 2022</h3> </a> </div> <div class="sf-publications-item__description"> <p>Report of the World Health Organization (&lrm;WHO)&lrm; Biosafety and Biosecurity Inspection Team of the Variola Virus Maximum Containment Laboratories... </p> </div> <div class="sf-publications-item__actions"> <div class="sf-publications-item__file"> <a class="download-url " href="https://iris.who.int/bitstream/handle/10665/377616/WHO-WHE-EPP-2024.1-eng.pdf?sequence=1" aria-label="Download" target="_blank">Download</a> </div> <div class="sf-publications-item__url"> <a href="https://www.who.int/publications/i/item/WHO-WHE-EPP-2024-1" class="page-url" aria-label="Read More">Read More</a> </div> </div> </div> </div> </div> <div class="sf-publications-item list-item col-sm-3"> <div class="sf-publications-item__container"> <figure class="sf-publications-item__figure"> <img src="https://iris.who.int/bitstream/handle/10665/376923/9789240095519-eng.pdf.jpg?sequence=4" alt="WHO advisory committee on variola virus research: report of the twenty-fifth meeting, Geneva, Switzerland, 25-26 October 2023" /> </figure> <div class="sf-publications-item__body"> <div class="sf-publications-item__header"> <div class="sf-publications-item__date"> <span>30 May 2024</span> </div> <a href="https://www.who.int/publications/i/item/9789240095519"> <h3 class="sf-publications-item__title">WHO advisory committee on variola virus research: report of the twenty-fifth meeting, Geneva, Switzerland,... </h3> </a> </div> <div class="sf-publications-item__description"> <p>The World Health Organization (WHO) Advisory Committee on variola virus Research (ACVVR), held its twenty-fifth meeting on 25-26 October 2023. The recommendations... </p> </div> <div class="sf-publications-item__actions"> <div class="sf-publications-item__file"> <a class="download-url " href="https://iris.who.int/bitstream/handle/10665/376923/9789240095519-eng.pdf?sequence=1" aria-label="Download" target="_blank">Download</a> </div> <div class="sf-publications-item__url"> <a href="https://www.who.int/publications/i/item/9789240095519" class="page-url" aria-label="Read More">Read More</a> </div> </div> </div> </div> </div> <div class="sf-publications-item list-item col-sm-3"> <div class="sf-publications-item__container"> <figure class="sf-publications-item__figure"> <img src="https://iris.who.int/bitstream/handle/10665/376927/WHO-WHE-EPP-2024.2-eng.pdf.jpg?sequence=4" alt="Report of the ‎WHO Biosafety and Biosecurity Inspection Team of the Variola Virus Maximum Containment Laboratories to the State Research Centre of Virology and Biotechnology: Koltsovo, Novosibirsk Oblast, Russian Federation, 2-7 October 2023" /> </figure> <div class="sf-publications-item__body"> <div class="sf-publications-item__header"> <div class="sf-publications-item__date"> <span>30 May 2024</span> </div> <a href="https://www.who.int/publications/i/item/WHO-WHE-EPP-2024-2"> <h3 class="sf-publications-item__title">Report of the ‎WHO Biosafety and Biosecurity Inspection Team of the Variola Virus Maximum Containment... </h3> </a> </div> <div class="sf-publications-item__description"> <p>Report of the World Health Organization (&lrm;WHO)&lrm; Biosafety and Biosecurity Inspection Team of the Variola Virus Maximum Containment Laboratories... </p> </div> <div class="sf-publications-item__actions"> <div class="sf-publications-item__file"> <a class="download-url " href="https://iris.who.int/bitstream/handle/10665/376927/WHO-WHE-EPP-2024.2-eng.pdf?sequence=1" aria-label="Download" target="_blank">Download</a> </div> <div class="sf-publications-item__url"> <a href="https://www.who.int/publications/i/item/WHO-WHE-EPP-2024-2" class="page-url" aria-label="Read More">Read More</a> </div> </div> </div> </div> </div> <div class="sf-publications-item list-item col-sm-3"> <div class="sf-publications-item__container"> <figure class="sf-publications-item__figure"> <img src="https://iris.who.int/bitstream/handle/10665/372843/9789240076310-eng.pdf.jpg?sequence=4" alt="WHO Advisory Committee on Variola Virus Research: report of the twenty-fourth meeting, Geneva, 29–30 November 2022" /> </figure> <div class="sf-publications-item__body"> <div class="sf-publications-item__header"> <div class="sf-publications-item__date"> <span>21 September 2023</span> </div> <a href="https://www.who.int/publications/i/item/9789240076310"> <h3 class="sf-publications-item__title">WHO Advisory Committee on Variola Virus Research: report of the twenty-fourth meeting, Geneva, 29–30... </h3> </a> </div> <div class="sf-publications-item__description"> <p>The World Health Organization (WHO) Advisory Committee on variola virus Research (ACVVR), held its twenty-fourth meeting on 29-30 November 2022 at WHO... </p> </div> <div class="sf-publications-item__actions"> <div class="sf-publications-item__file"> <a class="download-url " href="https://iris.who.int/bitstream/handle/10665/372843/9789240076310-eng.pdf?sequence=1" aria-label="Download" target="_blank">Download</a> </div> <div class="sf-publications-item__url"> <a href="https://www.who.int/publications/i/item/9789240076310" class="page-url" aria-label="Read More">Read More</a> </div> </div> </div> </div> </div> </div> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_C273_Col00" class="sf_colsIn col-md-12" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div class="section-heading"> <p>Videos</p> </div> <script type='text/javascript' src='/ResourcePackages/WHO/assets/dist/scripts/multimedia-modal.min.js?v=14.0.7729.18497'></script> <script async defer src="https://connect.facebook.net/en_US/sdk.js#xfbml=1&version=v3.2"></script> <div class="sf-multimedia"> <div class="sf-multimedia-list sf-multimedia-list__small row"> <div class="sf-multimedia-item sf-multimedia-item__video col-md-3 col-xs-6"> <a class="sf-multimedia-item__container" href="#" onclick='new ModalJS( "YoutubeVideo", "https://www.youtube.com/watch?v=Di3T2-IiFTs")'> <span class="sf-multimedia-item__link page-url play-button"></span> <figure class="sf-multimedia-item__figure" style="background-image: url('https://cdn.who.int/media/images/default-source/health-topics/smallpox/smallpox-thumb.tmb-549v.png?sfvrsn=8049fe6d_1');" role="img" aria-label="A black and white old photograph of a boy's face looking down at his arm." title="A black and white old photograph of a boy's face looking down at his arm."> <img src="https://cdn.who.int/media/images/default-source/health-topics/smallpox/smallpox-thumb.tmb-549v.png?sfvrsn=8049fe6d_1" alt="A black and white old photograph of a boy's face looking down at his arm." style="display: none;" /> </figure> <div class="sf-multimedia-item__body"> <div class="sf-multimedia-item__date">7 April 2023</div> <h3 class="sf-multimedia-item__heading">Smallpox eradication: science, solutions, solidarity</h3> <div class="sf-multimedia-item__actions"> <div class="sf-multimedia-item__url"> </div> </div> </div> </a> </div> <div class="sf-multimedia-item sf-multimedia-item__video col-md-3 col-xs-6"> <a class="sf-multimedia-item__container" href="#" onclick='new ModalJS( "YoutubeVideo", "https://www.youtube.com/watch?v=FZY3aHKigDU")'> <span class="sf-multimedia-item__link page-url play-button"></span> <figure class="sf-multimedia-item__figure" style="background-image: url('/images/default-source/health-topics/smallpox/smallpox-tedros.tmb-549v.png?Culture=en&sfvrsn=781438f9_2');" role="img" aria-label="" title=""> <img src="/images/default-source/health-topics/smallpox/smallpox-tedros.tmb-549v.png?Culture=en&sfvrsn=781438f9_2" alt="" style="display: none;" /> </figure> <div class="sf-multimedia-item__body"> <div class="sf-multimedia-item__date">8 May 2020</div> <h3 class="sf-multimedia-item__heading">Dr Tedros on the milestone of smallpox eradication and lessons learned for COVID-19 response</h3> <div class="sf-multimedia-item__actions"> <div class="sf-multimedia-item__url"> </div> </div> </div> </a> </div> <div class="sf-multimedia-item sf-multimedia-item__video col-md-3 col-xs-6"> <a class="sf-multimedia-item__container" href="#" onclick='new ModalJS( "YoutubeVideo", "https://www.youtube.com/watch?v=freX6WB8Cag")'> <span class="sf-multimedia-item__link page-url play-button"></span> <figure class="sf-multimedia-item__figure" style="background-image: url('https://cdn.who.int/media/images/default-source/health-topics/smallpox/smallpox-video-8may2020.tmb-549v.png?sfvrsn=af4a188_2');" role="img" aria-label="" title=""> <img src="https://cdn.who.int/media/images/default-source/health-topics/smallpox/smallpox-video-8may2020.tmb-549v.png?sfvrsn=af4a188_2" alt="" style="display: none;" /> </figure> <div class="sf-multimedia-item__body"> <div class="sf-multimedia-item__date">7 May 2020</div> <h3 class="sf-multimedia-item__heading">40th anniversary of smallpox eradication</h3> <div class="sf-multimedia-item__actions"> <div class="sf-multimedia-item__url"> </div> </div> </div> </a> </div> <div class="sf-multimedia-item sf-multimedia-item__video col-md-3 col-xs-6"> <a class="sf-multimedia-item__container" href="#" onclick='new ModalJS( "YoutubeVideo", "https://www.youtube.com/watch?v=_Tw9iif3ATQ&feature=youtu.be")'> <span class="sf-multimedia-item__link page-url play-button"></span> <figure class="sf-multimedia-item__figure" style="background-image: url('/images/default-source/health-topics/smallpox/live-stream-video-13december2019.tmb-549v.png?Culture=en&sfvrsn=96c80079_2');" role="img" aria-label="" title=""> <img src="/images/default-source/health-topics/smallpox/live-stream-video-13december2019.tmb-549v.png?Culture=en&sfvrsn=96c80079_2" alt="" style="display: none;" /> </figure> <div class="sf-multimedia-item__body"> <div class="sf-multimedia-item__date">13 December 2019</div> <h3 class="sf-multimedia-item__heading">Commemoration of 40 years since smallpox eradication - live stream 13 December 2019</h3> <div class="sf-multimedia-item__actions"> <div class="sf-multimedia-item__url"> </div> </div> </div> </a> </div> </div> </div> </div> </div> <div class="row" data-sf-element="Row"> <div id="PageContent_C255_Col00" class="sf_colsIn col-md-4" data-sf-element="Column 1" data-placeholder-label="Column 1"> <div class="section-heading"> <h2>Related health topics</h2> </div> <div class="list-view vertical-list vertical-list--image"> <div class="list-view--item vertical-list-item"> <a href="https://www.who.int/health-topics/international-health-regulations" class="link-container table" aria-label="International Health Regulations" role="link"> <div class="table-cell"> <div class="thumb"> <div class="background-image background-image--small" 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