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Soft Tissue Sarcoma | Conditions | UCSF Benioff Children's Hospitals

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<li><a rel="noopener noreferrer" href="https://give.ucsfbenioffchildrens.org/" target="_blank">Make a Gift</a></li> <li><a title="Get a Second Opinion" href="/refer-a-patient">Refer a Patient</a></li> </ul> <div class="mobile-nav-footer"> </div> </div> </div> </div> </div> </div> </div> </div> </header> <!-- /#header --> <!-- #content --> <main> <div id="content" class="container"> <div class="component conditions-hero main"> <div class="component-content"> <div class="conditions-hero-content"> <div class="conditions-hero-breadcrumb-wrapper"> <a href="/care/cancer">Cancer</a> </div> <h1 class="conditions-hero-content-header "><span>Soft</span> <span>tissue</span> <span>sarcoma</span></h1> <span class="lhn-anchor-mobile-open"></span> </div> <div class="conditions-hero-image"> <img src="/-/media/project/ucsf/ucsf-bch/images/condition/hero/soft-tissue-sarcoma-2x.jpg?h=1112&amp;iar=0&amp;w=1668&amp;rev=3419367a29864ea1bba911949bc807ec&amp;hash=F464F42C7F3E01571F6D0BE3DA01D045" alt="soft-tissue-sarcoma-2x" width="1668" height="1112" /> </div> </div> </div> <div class="component content container"> <div class="component-content"> <div class="row"><div class="col-lg-3"><div class="component share-print-email"> <div class="component-content"> <div class="share-component"> <a aria-label="Print Page" href="#" rel="nofollow" class="icon-ui-print" title="Print"></a> <a aria-label="Share Page" data-email-body="Thought you might want to see this:" class="icon-ui-share" data-email-body="Thought you might want to see this:" data-email-subject="Take a look at this link from UCSF"></a> </div> <div class="clearfix"></div> </div> </div> <aside class="component anchor-info-navigation" aria-label="Table of Contents"> <div class="component-content"> <ul> <li><a href="/conditions/soft-tissue-sarcoma#Overview">Overview</a></li> <li><a href="/conditions/soft-tissue-sarcoma#Signs_%26_symptoms">Signs &amp; symptoms</a></li> <li><a href="/conditions/soft-tissue-sarcoma#Diagnosis">Diagnosis</a></li> <li><a href="/conditions/soft-tissue-sarcoma#Treatment">Treatment</a></li> <li><a href="/conditions/soft-tissue-sarcoma#Where_to_get_care">Where to get care</a></li> <li><a href="/conditions/soft-tissue-sarcoma#Support_services">Support services</a></li> <li><a href="/conditions/soft-tissue-sarcoma#Helpful_resources">Helpful resources</a></li> </ul> </div> </aside></div><div class="col-lg-9"> <div class="component titled-rich-text rich-text col-xs-12"> <div class="component-content"> <h2 class="heading1 title-anchor field-title">Overview</h2><p>Soft tissues are the tissues that connect, support or surround organs of the body or other structures such as muscles, tendons, fat, blood vessels, nerves and tissue around the joints. Malignant or cancerous tumors that develop in a child's soft tissue are called sarcomas. They are relatively uncommon, accounting for less than one percent of all new cancer cases each year.</p> <p>Soft tissue sarcomas can develop almost anywhere in a child's body. About 50 percent are found in the arms, legs, hands or feet; 40 percent occur in the chest, back, hips, shoulder and abdomen; and 10 percent occur in the head and neck. There are many different kinds of soft tissue sarcomas that develop in children and young adults. They can invade surrounding tissue and spread to other organs of the body, forming secondary tumors. One of the most common forms is rhabdomyosarcoma, which begins growing in muscle tissue.</p> </div> </div> <div class="component cls-info-cards col-xs-12"> <div class="component-content"> <div class="cls-info-cards-columns"><div class="cls-info-cards-column info-cards-column-left"> <div class="component cls-info-card cls-info-card cls-info-card-small col-xs-12"> <div class="component-content"> <div class="cls-info-card-title"> <h2>Contact us</h2> </div> <div class="cls-info-card-content"> <p>To request an appointment, give us a call.</p> <p><button type="button" class="btn btn-tertiary"><span class="icon-ui-phone"></span><a href="tel:877-822-4453">(877) 822-4453</a></button></p> </div> </div> </div> </div><div class="cls-info-cards-column info-cards-column-right"></div></div> </div> </div> <div class="component titled-rich-text rich-text col-xs-12"> <div class="component-content"> <h2 class="heading1 title-anchor field-title">Signs &amp; symptoms</h2><p>In their early stages, soft tissue sarcomas usually don't produce any symptoms. Because soft tissue is relatively elastic, tumors can grow rather large, pushing aside normal tissue, before they are felt or cause problems. The first symptom is usually a painless lump or swelling.</p> <p> As the tumor grows, it may cause pain or soreness as it presses against nearby nerves and muscles.</p> </div> </div> <div class="component titled-rich-text rich-text col-xs-12"> <div class="component-content"> <h2 class="heading1 title-anchor field-title">Diagnosis</h2><p>The only reliable way to determine if a soft tissue tumor is benign or cancerous is through a surgical <a href="/medical-tests/biopsy">biopsy</a>. During this procedure, your child's doctor makes an incision or uses a special needle to remove a sample of tumor tissue. A pathologist examines the tissue under a microscope.</p> <p> If cancer is present, the pathologist can usually determine the type of cancer and its grade.</p> <p>The grade of the tumor is determined by how abnormal the cells appear when examined under a microscope. The grade predicts the probable growth rate of the tumor and its tendency to spread. Low-grade sarcomas, although cancerous, are unlikely to metastasize or spread. High-grade sarcomas are more likely to spread to other parts of the body.</p> </div> </div> <div class="component titled-rich-text rich-text col-xs-12"> <div class="component-content"> <h2 class="heading1 title-anchor field-title">Treatment</h2><p>Treatment options for soft tissue sarcomas include surgery, radiation therapy and chemotherapy. The specific treatment plan for your child will depend on the stage of the cancer, which is based on size and grade of the tumor and whether it has spread to other parts of the body.</p> <p>In some cases, genetic mutations are involved in infant and childhood soft tissue sarcomas. If doctors identify a genetic link, families may be referred to the <a href="/clinics/medical-genetics-and-genomics-clinic">Medical Genetics and Genomics Clinic</a>&nbsp;for counseling.</p> <h3>Surgery</h3> <p>Surgery is the most common treatment for soft tissue sarcomas. Your doctor may remove the cancer and a safe margin of healthy tissue around it. Depending on the size and location of the sarcoma, it may be necessary to remove all or part of an arm or leg but amputation is rare. In most cases radiation or chemotherapy is given before surgery to shrink the tumor, or after surgery to kill remaining cancer cells.</p> <h3>Radiation Therapy</h3> <p>Radiation therapy is treatment with high-dose X-rays, given before surgery to shrink tumors or after surgery to kill any cancer cells that may have been left behind.</p> <h3>Chemotherapy</h3> <p>Chemotherapy is treatment with anti-cancer drugs. Chemotherapy may be used to shrink tumors and make the tumor more accessible for removal by surgery or radiation treatment, or sometimes both. Patients with soft tissue sarcomas usually receive chemotherapy intravenously, meaning it's injected into a blood vessel.</p> <p>If the cancer has spread to other areas of the body, treatment is more difficult. In some situations, intense therapy with drugs, radiation and surgery followed by bone marrow or peripheral stem cell transplant may be used. Some children may be eligible to participate in research projects, or clinical trials, to test new anti-cancer drugs.</p> </div> </div> <div class="component disclaimer col-xs-12"> <div class="component-content"> <div class="field-ucsf-bch-text"><p><em>UCSF Benioff Children's Hospitals medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your child's doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your child's provider.</em></p></div> </div> </div> <div class="component numbered-clinic-rollup col-xs-12"> <div class="component-content"> <h2 class="heading1">Where to get care (3)</h2> <div class="cards"> <div class="numbered-clinic-card"> <div class="numbered-clinic-card-first"> <div class="numbered-clinic-card-first-image"> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/clinic/numbered-clinic-card/infusion-center-320x320-2x.jpg?rev=d64cdded554a41878d9f6cd568e77bcd&amp;hash=4B6B60FE24108606C4CF89834F32B8D0" alt="infusion-center-320x320-2x" width="640" height="640"> <span>3</span> </div> <h2 class="numbered-clinic-card-header first">Infusion Center</h2> </div> <div class="numbered-clinic-card-second"> <h2 class="numbered-clinic-card-header second">Infusion Center</h2> <div class="numbered-clinic-card-second-locations"> <a href="/clinics/infusion-center" target="_self" title="Infusion Center"></a> <span><p>San Francisco / Oakland / Walnut Creek</p></span> </div> </div> </div> <div class="numbered-clinic-card"> <div class="numbered-clinic-card-first"> <div class="numbered-clinic-card-first-image"> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/clinic/numbered-clinic-card/oncology-clinic-320x320-2x.jpg?rev=aefa5d584aa24b6bbf865b4f7b3fe3d7&amp;hash=E86BC5B421E49D97C1D57C84BAE20ABF" alt="oncology-clinic-320x320-2x" width="640" height="640"> <span>3</span> </div> <h2 class="numbered-clinic-card-header first">Oncology Clinic</h2> </div> <div class="numbered-clinic-card-second"> <h2 class="numbered-clinic-card-header second">Oncology Clinic</h2> <div class="numbered-clinic-card-second-locations"> <a href="/clinics/oncology-clinic" target="_self" title="Oncology Clinic"></a> <span><p>San Francisco / Oakland / Walnut Creek</p></span> </div> </div> </div> <div class="numbered-clinic-card"> <div class="numbered-clinic-card-first"> <div class="numbered-clinic-card-first-image"> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/clinic/numbered-clinic-card/survivorship-clinic-320x320-2x.jpg?rev=a1da8453711f4cea9d3abbd4f3d070b6&amp;hash=4FD6C306EDF7AEBE8727F5FBF6D62FE5" alt="disorders-of-sex-development-clinic-320x320-2x" width="640" height="640"> <span>2</span> </div> <h2 class="numbered-clinic-card-header first">Survivorship Program</h2> </div> <div class="numbered-clinic-card-second"> <h2 class="numbered-clinic-card-header second">Survivorship Program</h2> <div class="numbered-clinic-card-second-locations"> <a href="/clinics/survivorship-program" target="_blank" title="Survivorship Program"></a> <span><p>Oakland / San Francisco</p></span> </div> </div> </div> </div> </div> </div><div class="component patient-services cards-component col-xs-12"> <div class="component-content"> <div class="patient-services-header"> <h2 class="heading1 title-anchor"> Support services </h2> <div class="view-all"> </div> </div> <div class="cards"> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/camp-okizu" class="phantom-link" title="Camp Okizu"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/service/hero/camp-okizu-2x.jpg?h=376&amp;w=973&amp;rev=54abdc333b254dc5878d7b60dc926a3c&amp;hash=1A66121BCE3E3160A4D90AFCA1CDD28E" alt="camp-okizu-2x" width="2880" height="1112" /> <div class="field-icon"> <div class="eyebrow"> </div> </div> <p class="font-larger"> Camp Okizu </p> <p> This overnight summer camp for children with cancer, siblings and families offers fun activities, education sessions and support in a beautiful setting. </p> <span class="field-read-more-link"><span class="include-ucsf-arrow"></span></span> </div> </div> </div> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/child-life" class="phantom-link" title="Child Life"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/service/hero/child-life-hero-2x-v1.jpg?h=376&amp;w=973&amp;rev=2b62da174c47471ab37503a4aee376d7&amp;hash=D2BEBDE74B2CDE51B159EFF3E08A4132" alt="" width="2880" height="1112" /> <div class="field-icon"> <div class="eyebrow"> </div> </div> <p class="font-larger"> Child Life </p> <p> Certified child life specialists ease the stress and anxiety of childhood illness through therapeutic play, schooling and family-focused support. </p> <span class="field-read-more-link"><span class="include-ucsf-arrow"></span></span> </div> </div> </div> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/family-amenities" class="phantom-link" title="Family Amenities"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/service/hero/family-amenities1-2x.jpg?h=376&amp;w=973&amp;rev=432dbfb1d5cc47c3bf265a316fcf8b8c&amp;hash=BFD6C7BC3D86B44792582F7300E78430" alt="" width="2880" height="1112" /> <div class="field-icon"> <div class="eyebrow"> </div> </div> <p class="font-larger"> Family Amenities </p> <p> Family-friendly amenities help you relax and take care of yourself while staying close to your child. We offer lounges, kitchens, showers, breastfeeding rooms and more. </p> <span class="field-read-more-link"><span class="include-ucsf-arrow"></span></span> </div> </div> </div> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/glogau-teddy-bear-rescue-fund" class="phantom-link" title="Glogau Teddy Bear Rescue Fund"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/service/hero/glogau-teddy-bear-rescue-fund-2x.jpg?h=376&amp;w=973&amp;rev=0dc09555543b41f5b4d52f1aa9b96eec&amp;hash=E86670B13A31E1EEAE1DAD8AD2119D84" alt="glogau-teddy-bear-rescue-fund-2x" width="2880" height="1112" /> <div class="field-icon"> <div class="eyebrow"> </div> </div> <p class="font-larger"> Glogau Teddy Bear Rescue Fund </p> <p> Families that need additional assistance during their child&#39;s hospital stay have access to toys, hotel vouchers and other amenities. Find out more. </p> <span class="field-read-more-link"><span class="include-ucsf-arrow"></span></span> </div> </div> </div> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/international-services" class="phantom-link" title="International Services"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/service/hero/international-services-2x.jpg?h=376&amp;w=973&amp;rev=a295537e635e4e4983a2955c6221f5be&amp;hash=6AA251AB263516FECDE335D7C1DA2A84" alt="international-services-2x" width="2880" height="1112" /> <div class="field-icon"> <div class="eyebrow"> </div> </div> <p class="font-larger"> International Services </p> <p> If you&#39;re coming to UCSF from outside the U.S., we coordinate your child&#39;s appointments and provide other helpful services. Here&#39;s how to get started. </p> <span class="field-read-more-link"><span class="include-ucsf-arrow"></span></span> </div> </div> </div> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/interpreter-services-and-communication-assistance" class="phantom-link" title="Interpreter Services &amp; Communication Assistance"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/service/hero/interpreter-services-and-communication-assistance-2x.jpg?h=376&amp;w=973&amp;rev=8dec0cd4e0d141df931ac7a1596b6718&amp;hash=2198F2762E1DF198611DCE4BA0B924D8" alt="interpreters-2x" width="2880" height="1112" /> <div class="field-icon"> <div class="eyebrow"> </div> </div> <p class="font-larger"> Interpreter Services &amp; Communication Assistance </p> <p> Interpreter services in many languages and TDDs are available for families that need help communicating with care teams. Here&#39;s how to access them. </p> <span class="field-read-more-link"><span class="include-ucsf-arrow"></span></span> </div> </div> </div> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/social-services" class="phantom-link" title="Social Services"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/service/hero/social-services-2x.jpg?h=376&amp;w=973&amp;rev=b7db25aa488a49c4ab7f4559076e384b&amp;hash=E1AA5DBFDE00B38752727BB311444033" alt="social-services-2x" width="2880" height="1112" /> <div class="field-icon"> <div class="eyebrow"> </div> </div> <p class="font-larger"> Social Services </p> <p> Social workers ease the effect of illness, injury and hospitalization on your family with counseling and assistance to help you navigate the challenges. </p> <span class="field-read-more-link"><span class="include-ucsf-arrow"></span></span> </div> </div> </div> <div class="card"> <div class="component-content"> <div class="card-content"> <a href="/services/spiritual-care" class="phantom-link" title="Spiritual Care"></a> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/service/hero/spiritual-care-2x.jpg?h=376&amp;w=973&amp;rev=c9c3696232e4424690cd4a0e701e1426&amp;hash=E72E1ABBE378F88130FF7DA286EBDD03" alt="spiritual-care-2x" width="2880" height="1112" /> <div class="field-icon"> <div class="eyebrow"> </div> </div> <p class="font-larger"> Spiritual Care </p> <p> Chaplains help UCSF patients, families and staff cope with the spiritual and emotional challenges of childhood illness. Learn more. </p> <span class="field-read-more-link"><span class="include-ucsf-arrow"></span></span> </div> </div> </div> </div> </div> </div> <div class="component link-list meta-links col-xs-12"> <div class="component-content"> <div> <h2 class="heading1 title-anchor">Helpful resources</h2> <p class="font-larger"></p> </div> <ul class="use-arrow-icon "> <li class="item0 odd first "> <p class="font-smaller"> <a href="http://www.cancer.org/docroot/home/index.asp" target=_blank>American Cancer Society</a> </p> </li> <li class="item1 even "> <p class="font-smaller"> <a href="http://www.candlelighters.org/" target=_blank>Candlelighters Childhood Cancer Foundation</a> </p> </li> <li class="item2 odd "> <p class="font-smaller"> <a href="http://www.childrensoncologygroup.org/" target=_blank>Children&#39;s Oncology Group</a> </p> </li> <li class="item3 even last "> <p class="font-smaller"> <a href="https://www.cancer.gov/types/soft-tissue-sarcoma" target=_blank>National Cancer Institute</a> </p> </li> </ul> </div> </div> <div class="component accolades col-xs-12"> <div class="component-content"> <h2 class="heading1">Awards &amp; recognition</h2> <ul> <li class="component accolade"> <div class="component-content"> <div class="image-wrapper"> <img loading="lazy" src="/-/media/project/ucsf/ucsf-bch/images/accolades/us-news-badges-2024-2025/us-news-best-childrens-hospitals-cancer-24-25-200x200-2x.png?h=200&amp;iar=0&amp;w=200&amp;rev=1df8142a424842aea0494fd4e28f9778&amp;hash=C5DC0DC2128101A18181D77A7E61C597" alt="" width="200" height="200" /> </div> <p class="font-larger">Best in Northern California for cancer care</p> </div> </li> <li class="component accolade"> <div class="component-content"> <div class="image-wrapper"> <img loading="lazy" 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