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RCA is committed to providing a platform for discovery of high-quality articles, journals, scholars, and academic assistants by biomedical researchers, universities, hospitals, research institutions, funding agencies, librarians, publishers, and journal editors worldwide." /> </head> <body> <form method="post" action="./search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" id="form1"> <div class="aspNetHidden"> <input type="hidden" name="__EVENTTARGET" id="__EVENTTARGET" value="" /> <input type="hidden" name="__EVENTARGUMENT" id="__EVENTARGUMENT" value="" /> <input type="hidden" name="__VIEWSTATE" id="__VIEWSTATE" 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(confirm("Confirm Delete the Friend?")) { LoadingPanel.Show(); var uri = "/api/BpgUser/DeleteFriend?id=" + id; $.ajax({ type: "get", url: uri, async: false }).done(function () { window.location.href = window.location.href; }); } } function SelectAllFriend() { $("input[name='checkfriend']").each(function () { $(this).attr("checked", $('#selectAllFriend').prop("checked")); }); onCheckFriendClick(); } function onCheckFriendClick() { var itemArray = new Array(); $("input[name='checkfriend']:checked").each(function () { itemArray.push($(this).val()); }); if (itemArray.length > 0) { $("#BatchMessageContainer").show(); } else { $("#BatchMessageContainer").hide(); } } function SendBatchMessages() { var itemArray = new Array(); var idArray = new Array(); $("input[name='checkfriend']:checked").each(function () { itemArray.push($(this).val()); idArray.push($(this).attr("data-id")); }); if (itemArray.length > 0) { if (itemArray.length == 1) { OpenMessage(idArray[0], itemArray[0]); } else { var friendIds = JSON.stringify(itemArray); OpenBatchFriendMessage(friendIds); } } } function ImportSingleArticle(doi, controlId) { if (doi != '') { LoadingPanel.Show(); var uri = "/api/BpgUser/ImportArticle?doiPmid=" + encodeURIComponent(doi); $.ajax({ type: "get", url: uri, beforeSend: function (xhr) { LoadingPanel.Show(); } }).done(function (data) { LoadingPanel.Hide(); if (data) { alert("Import Successfully!"); var currentControl = $("#" + controlId); currentControl.parent().hide(); } }).always(function () { LoadingPanel.Hide(); }); } } function ImportAllArticles() { LoadingPanel.Show(); var term = getQueryString2('term'); var uri = "/api/BpgUser/ImportArticlesFromSearch?term=" + term; $.ajax({ type: "get", url: uri, beforeSend: function (xhr) { LoadingPanel.Show(); } }).done(function () { LoadingPanel.Hide(); alert("Imorting is executing!"); }).always(function () { LoadingPanel.Hide(); }); } </script> <input type="hidden" name="ctl00$RootHolder$RCAId" id="RCAId" /> <input type="hidden" name="ctl00$RootHolder$RCAUserType" id="RCAUserType" /> <input type="hidden" name="ctl00$RootHolder$UserId" id="UserId" /> <input type="hidden" name="ctl00$RootHolder$IsCurrentUser" id="IsCurrentUser" /> <div class="search-result-container cl"> <div class="search-centered cl"> <div class="search-result-center-container cl"> <div class="left-part"> <div id="RootHolder_ExportContainer" class="export-container"> <div class="dxbButton_MetropolisBlue DefaultButton-Oral dxbButtonSys dxbTSys" id="RootHolder_DownloadArticle" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_DownloadArticle_I" class="dxb-hb" value="Download" type="button" name="ctl00$RootHolder$DownloadArticle" /><span class="dx-vam">Download</span> </div> </div><script id="dxss_1963926087" type="text/javascript">  </script> </div> <div class="mnavbar"> <table class="total-count-container cl"> <tr> <td> <a href="/" target="_blank" class="white-link">Total Articles</a> </td> </tr> </table> </div> <div class="mnavbox"> <label id="RootHolder_TotalCountText" class="total-count-text">366</label> <br /> <label style="font-size: 14px;">(from Reference Citation Analysis)</label> <div id="RootHolder_SearchArticlePDFContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithPdf" type="checkbox" id="RootHolder_ArticlesWithPdf" class="ArticlesWithPdf" onclick="SearchArticleWithPDF();" /> <label for="ArticlesWithPdf">Article PDFs (176)</label> </div> <div id="RootHolder_SearchTCContainer" style="padding-top: 1rem;"> <input name="ctl00$RootHolder$ArticlesWithTC" type="checkbox" id="RootHolder_ArticlesWithTC" class="ArticlesWithTC" onclick="SearchArticleWithTC();" /> <label for="ArticlesWithTC">Cited by ≥ 1 (228)</label> </div> </div> <div class="mnavbar" id="SearchedNameTitle"> <div> Searched Name </div> </div> <div class="mnavbox" id="SearchedNameText"> <label id="RootHolder_SearchTermText" class="search-term-text">Real-Time 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id="aisortedCheck" onclick="SetSorted('ai')" name="sortedbycheck" value="aisorted" /> <a href="javascript:void(0);" name="sortedby" onclick="SetSorted('ai')" id="aisorted">Impact Index Per Article</a> </li> <li> <input type="radio" id="citedf6sortedCheck" onclick="SetSorted('citedf6')" name="sortedbycheck" value="citedf6sorted" /> <a href="javascript:void(0);" name="sortedby" onclick="SetSorted('citedf6')" id="citedf6sorted"> Citation(s) in <i>RCA</i> </a> </li> </ul> </div> <div id="RootHolder_ResultsAnalysisContainer"> <div class="mnavbar"> <div> Results Analysis </div> </div> <div class="mnavbox"> <ul class="ul analysis-list"> <li> <input type="checkbox" id="YearAnalysis" onclick="InitializeResultAnalysisBtn();" name="analysis-check" value="year" />  <label for="YearAnalysis">Year Published Analysis</label> </li> <li> <input type="checkbox" id="ArticleTypeAnalysis" onclick="InitializeResultAnalysisBtn();" name="analysis-check" value="at" />  <label for="ArticleTypeAnalysis">Article 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id="PubDateFacetContainer"> <ul class="ul sortedby-list"> <li> <a href="javascript:SubmitSingleFacetSearch('create','6');">Today (<span id="indexCount6"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','5');">Yesterday (<span id="indexCount5"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','4');">This Week (<span id="indexCount4"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','3');">Last Week (<span id="indexCount3"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','2');">Current Month (<span id="indexCount2"></span>)</a> </li> <li> <a href="javascript:SubmitSingleFacetSearch('create','1');">Last Month (<span id="indexCount1"></span>)</a> </li> </ul> </div> <div id="journalFacetContainer"> <div class="mnavbar"> <div> Publication Titles </div> </div> <div class="mnavbox"> <div id="journalFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('journal');" class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinejournalcheck" target="_self">Refine</a> </div> </div> </div> <div id="fundFacetContainer"> <div class="mnavbar"> <div> Grant Agencies </div> </div> <div class="mnavbox"> <div id="fundFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('fund');" class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinefundcheck" target="_self">Refine</a> </div> </div> </div> <div id="subjectFacetContainer"> <div class="mnavbar"> <div> Category </div> </div> <div class="mnavbox"> <div id="subjectFacetItemContainer"> </div> <div class="refine-btn-container cl"> <a href="javascript:ShowResultItems('subject');" class="refine-link-btn" target="_self">Show more</a>   <a href="javascript:SubmitFacetSearch();" class="refine-link-btn refine-link-btn-right" name="refinesubjectcheck" target="_self">Refine</a> </div> </div> </div> </div> </div> <div class="right-part"> <div class="mnavbar" style="margin-bottom: 0.625rem;"> <div> Journal Articles </div> </div> <table class="article-result-list cl"> <thead> <tr> <td> <span class="dxeBase_MetropolisBlue" id="RootHolder_SearchResultList_NumberTitle">Number</span> </td> <td> <span class="dxeBase_MetropolisBlue" id="RootHolder_SearchResultList_NameTitle">Citation Analysis</span> </td> </tr> </thead> <tbody> <tr id="articlerow1"> <td style="min-width: 40px; text-align: center;"> 1 </td> <td> <div id="citation1" class="article-citation"> <b>Edelmann S</b>, Savini C, Moor D, Lämke J, Lieske K, Mazzara M, Emons H, Mankertz J, Weidner C. Does DNA extraction affect the specificity of a PCR method claiming the specific detectability of a genome-edited plant? <em>GM CROPS & FOOD</em> 2024;<b>15</b>:352-360. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39543963' target='_blank'>39543963</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572162' target='_blank'>PMC11572162</a> DOI: <a href='https://dx.doi.org/10.1080/21645698.2024.2423441' target='_blank'>10.1080/21645698.2024.2423441</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/21645698.2024.2423441','39543963', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(1);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(1);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(1);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1080/21645698.2024.2423441' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/20/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/17/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv1" value="10.1080/21645698.2024.2423441" /> <div style="display: none" id="articleAbstract1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Under current EU legislation, genetically modified organisms (GMOs) and derived food and feed products must be authorized as GM food, feed, or seed and appropriate detection methods must be made available for use in official controls. A Real-Time PCR method has recently been published by Chhalliyil et al. claiming to be specific for the detection and identification of genome-edited oilseed rape (OSR) lines commercialized in North America. In a previous study, we have independently assessed this method in three reference laboratories for sensitivity, specificity, and robustness. We found that the method does not meet all the minimum performance requirements (MPR) for GMO testing in the EU, which contradicts the claims of the method developer. Here we show, in addition to the previously published method assessment study that a modified DNA extraction is not the reason for the contradictory findings and does not affect the specificity of the method. We also discuss the procedures recently proposed by the method developers for interpreting PCR results with high Cq values. </div> <a href="javascript:ShowArticleAbstract(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA+extraction%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA extraction</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22GMO+detection%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">GMO detection</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22genome+editing%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">genome editing</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22official+control%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">official control</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22oilseed+rape+(OSR)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">oilseed rape (OSR)</a></li></ul> <a href="javascript:ShowArticleKeywords(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plants%2c+Genetically+Modified%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plants, Genetically Modified/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA%2c+Plant%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA, Plant/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Editing%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Editing/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genome%2c+Plant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genome, Plant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sensitivity+and+Specificity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sensitivity and Specificity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Polymerase Chain Reaction/methods</a></li></ul> <a href="javascript:ShowArticleMeSH(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(1);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow2"> <td style="min-width: 40px; text-align: center;"> 2 </td> <td> <div id="citation2" class="article-citation"> <b>Sarli M</b>, De Salvo MN, Díaz Pérez PM, Cicuttin GL, Nava S, Sebastian PS. Development and evaluation of a TaqMan® real-time PCR assay for species-specific detection of Ehrlichia canis. <em class='incite-journal-name' onclick='ShowInCiteJournal(8017);'>Diagn Microbiol Infect Dis</em> 2024;<b>110</b>:116517. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39217856' target='_blank'>39217856</a> DOI: <a href='https://dx.doi.org/10.1016/j.diagmicrobio.2024.116517' target='_blank'>10.1016/j.diagmicrobio.2024.116517</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.diagmicrobio.2024.116517','39217856', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(2);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(2);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(2);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.diagmicrobio.2024.116517' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8017);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv2" value="10.1016/j.diagmicrobio.2024.116517" /> <div style="display: none" id="articleAbstract2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The aim of this work was to develop a real-time PCR assay with a TaqMan® probe that detects a species-specific part of the 16S rDNA gene of Ehrlichia canis. Canine blood samples (n = 207), collected and tested by a conventional PCR assay within a study conducted by De Salvo et al., were simultaneously analyzed with the novel designed real-time PCR, and the results of both assays were compared. The agreement between the two methods was 97.6 % with a kappa value of 0.92186. Hereby, the standard error was 0.034416 and the 95 % confidence interval from 0.8544 to 0.98931. While the conventional PCR assay showed false negative results (2.42 %; 5/207), the real-time PCR assays showed a specificity of 100 %. The results of the current study showed that the developed assay presents sensitivity and specificity for the detection of E. canis in blood samples, adding a new tool for the diagnosis of this pathogen. </div> <a href="javascript:ShowArticleAbstract(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Canine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Canine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Haemoparasites%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Haemoparasites</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Tick-borne+disease%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Tick-borne disease</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Veterinary+medicine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Veterinary medicine</a></li></ul> <a href="javascript:ShowArticleKeywords(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ehrlichia+canis%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ehrlichia canis/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fveterinary%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/veterinary</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Species+Specificity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Species Specificity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RNA%2c+Ribosomal%2c+16S%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RNA, Ribosomal, 16S/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ehrlichiosis%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ehrlichiosis/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ehrlichiosis%2fveterinary%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ehrlichiosis/veterinary</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sensitivity+and+Specificity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sensitivity and Specificity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dogs%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dogs</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ticks%2fmicrobiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ticks/microbiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dog+Diseases%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dog Diseases/diagnosis</a></li></ul> <a href="javascript:ShowArticleMeSH(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(2);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow3"> <td style="min-width: 40px; text-align: center;"> 3 </td> <td> <div id="citation3" class="article-citation"> <b>Pomianowski K</b>, Burzyński A. Reference gene selection for real-time qPCR in European flounder (Platichthys flesus) using organ-specific RNA-seq data. <em class='incite-journal-name' onclick='ShowInCiteJournal(17395);'>Mol Biol Rep</em> 2024;<b>52</b>:3. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39570445' target='_blank'>39570445</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11582196' target='_blank'>PMC11582196</a> DOI: <a href='https://dx.doi.org/10.1007/s11033-024-10105-7' target='_blank'>10.1007/s11033-024-10105-7</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s11033-024-10105-7','39570445', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(3);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(3);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(3);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(3);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s11033-024-10105-7' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17395);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/22/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv3" value="10.1007/s11033-024-10105-7" /> <div style="display: none" id="articleAbstract3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">The European flounder is readily chosen as an experimental subject and model in physiological and ecotoxicological studies mostly because of its adaptability to laboratory conditions. Many studies utilise a quantitative PCR (qPCR) approach to ascertain the expression of target genes under experimental conditions. Such an approach relies heavily on the selection of reference genes with stable expression. Yet certain housekeeping genes are commonly used in this role, often without due consideration of their overall expression patterns. Therefore, new approaches should be developed to identify stable reference genes for a given species and to expand the general pool of genes suitable for the reference in qPCR analysis. </div><div class="abstract-label">METHODS AND RESULTS</div><div class="abstract-content">Here RNA-seq data of nine flounder organs led to identify four candidate genes of the most stable expression. It was achieved by differential expression analysis and tritoconstrictor script. Specific primers were designed for the complete ORF as well as for qPCR analysis. RT-qPCR efficiencies were tested on ORF amplicon templates. Most of the genes tested showed good amplification in a wide range of template dilutions (107-101), with a correlation coefficient (R2) ranging from 0.991 to 0.998 and a consistent efficiency (E) (Sybr Green I staining and TaqMan molecular probe). </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">The proposed approach based on differential expression analysis and a new bioinformatic tool is an appropriate selection method of candidates for reference genes in qPCR. The proposed approach, combining differential expression analysis with a new bioinformatics tool, provides an effective method for selecting reference gene candidates for qPCR. As a result, we can propose four genes (polr2f, yif1a, sf3b6, uba52), each with a set of validated primers, as suitable for consideration as reference genes in qPCR analysis in European flounder, an emerging model species. </div> <a href="javascript:ShowArticleAbstract(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Differential+expression+analysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Differential expression analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Fish%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Fish</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22HKG%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">HKG</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Housekeeping+genes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Housekeeping genes</a></li></ul> <a href="javascript:ShowArticleKeywords(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Flounder%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Flounder/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RNA-Seq%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RNA-Seq/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Essential%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Essential/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Organ+Specificity%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Organ Specificity/genetics</a></li></ul> <a href="javascript:ShowArticleMeSH(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Narodowe+Centrum+Nauki%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">2017/27/B/NZ4/01259 Narodowe Centrum Nauki</a></li></ul> <a href="javascript:ShowArticleGrant(3);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow4"> <td style="min-width: 40px; text-align: center;"> 4 </td> <td> <div id="citation4" class="article-citation"> <b>Boccanegra B</b>, Lenti R, Mantuano P, Conte E, Tulimiero L, Piercy RJ, Cappellari O, Hildyard JCW, De Luca A. Determination of qPCR reference genes suitable for normalizing gene expression in a novel model of Duchenne muscular dystrophy, the D2-mdx mouse. <em class='incite-journal-name' onclick='ShowInCiteJournal(19324);'>PLoS One</em> 2024;<b>19</b>:e0310714. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39535998' target='_blank'>39535998</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11560031' target='_blank'>PMC11560031</a> DOI: <a href='https://dx.doi.org/10.1371/journal.pone.0310714' target='_blank'>10.1371/journal.pone.0310714</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1371/journal.pone.0310714','39535998', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(4);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(4);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(4);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1371/journal.pone.0310714' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19324);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/16/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv4" value="10.1371/journal.pone.0310714" /> <div style="display: none" id="articleAbstract4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Duchenne muscular dystrophy (DMD) is a X-linked neuromuscular disorder arising from mutations in the dystrophin gene, leading to a progressive muscle wasting and disability. Currently there is no universal therapy, and there is thus a strong interest in preclinical studies for finding novel treatments. The most widely used and characterized mouse model for DMD is the C57BL/10ScSn-Dmdmdx/J (BL10-mdx), but this model exhibits mild pathology and does not replicate key features of human disease. The D2.B10-Dmdmdx/J (D2-mdx) mouse is a more recent model which seems to better mimics the complex human DMD phenotype. However, the D2-mdx mouse remains less extensively characterised than its BL10-mdx counterpart. Quantitative PCR analysis of gene expression is an important tool to monitor disease progression and evaluate therapeutic efficacy, but measurements must be normalised to stably expressed reference genes, which should ideally be determined and validated empirically. We examined gene expression in the gastrocnemius (GC), diaphragm (DIA) and heart in the D2-mdx mouse, the BL10-mdx mouse, and appropriate strain-matched wild-type controls (D2-wt and BL10-wt), from 4 to 52 weeks of age, using a large panel of candidate references (ACTB, AP3D1, CSNK2A2, GAPDH, HPRT1, PAK1IP1, RPL13A, SDHA, and in the heart, also HTATSF1 and HMBS). Data was analyzed using GeNorm, Bestkeeper, deltaCt and Normfinder algorithms to identify stable references under multiple possible scenarios. We show that CSNK2A2, AP3D1 and ACTB represent strong universal reference genes in both GC and DIA, regardless of age, muscle type, strain and genotype, while HTATSF1 and SDHA are optimal for the heart. GAPDH, HPRT1 and RPL13A were conversely revealed to be poor references, showing tissue-, age- or disease-specific changes in expression. Our results illustrate the importance of determining appropriate reference genes for specific comparative scenarios, but also reconfirm that universal panels can nevertheless be identified for normalising gene expression studies in even complex pathological states. </div> <a href="javascript:ShowArticleAbstract(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <a href="javascript:ShowArticleKeywords(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Muscular+Dystrophy%2c+Duchenne%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Muscular Dystrophy, Duchenne/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+mdx%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred mdx</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Muscle%2c+Skeletal%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Muscle, Skeletal/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Muscle%2c+Skeletal%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Muscle, Skeletal/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diaphragm%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diaphragm/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diaphragm%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diaphragm/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myocardium%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myocardium/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Myocardium%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Myocardium/pathology</a></li></ul> <a href="javascript:ShowArticleMeSH(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22PNRR+-+AGE-IT%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">PNRR - AGE-IT</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Of+Mice+and+Measures+OMAM+-+Charley%27s+Fund%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Of Mice and Measures OMAM - Charley's Fund</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22PRIN+MUR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">PRIN MUR</a></li></ul> <a href="javascript:ShowArticleGrant(4);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow5"> <td style="min-width: 40px; text-align: center;"> 5 </td> <td> <div id="citation5" class="article-citation"> <b>Li C</b>, Zhou L, Ma X, Zhu L, Li J, Meng L, Han M, Wang D, Shen H, Liu C. Stability assessment of housekeeping genes for qRT-PCR in <i>Yersinia enterocolitica</i> cultured at 22°C and 37°C. <em class='incite-journal-name' onclick='ShowInCiteJournal(16915);'>Microbiol Spectr</em> 2024;<b>12</b>:e0114624. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39365096' target='_blank'>39365096</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536982' target='_blank'>PMC11536982</a> DOI: <a href='https://dx.doi.org/10.1128/spectrum.01146-24' target='_blank'>10.1128/spectrum.01146-24</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1128/spectrum.01146-24','39365096', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(5);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(5);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(5);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(5);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1128/spectrum.01146-24' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(16915);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/05/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv5" value="10.1128/spectrum.01146-24" /> <div style="display: none" id="articleAbstract5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Yersinia enterocolitica, a species within the genus Yersinia, thrives optimally at 22-25°C but can also grow at the mammalian core body temperature of 37°C. This dual temperature adaptability necessitates establishing both temperature conditions in research to examine the effects on various biological processes. In quantitative real-time PCR (qRT-PCR) assays, the selection of appropriate housekeeping genes is vital for data accuracy. Nevertheless, the lack of alternatives and information often leads to the default use of the 16S rRNA gene despite potential limitations. This investigation sourced 16 potential reference genes through a comprehensive review of the literature and transcriptome sequencing data analysis. We validated the expression stability of these genes via qRT-PCR across 12 Y. enterocolitica strains, representing the four prevalent serotypes O:3, O:5,27, O:8, and O:9, isolated from diarrheal patient stool samples. This approach aimed to minimize the impact of serotype heterogeneity. After acquiring Cq values, gene stability was evaluated using four established algorithms-ΔCq, geNorm, NormFinder, and BestKeeper-and subsequently synthesized into a consolidated ranking through the Robust Rank Aggregation (RRA) method. Our study suggests that the genes glnS, nuoB, glmS, gyrB, dnaK, and thrS maintain consistent expression across varying culture temperatures, supporting their candidacy as robust housekeeping genes. We advise against the exclusive use of 16S rRNA for this purpose. Should tradition prevail in its utilization, it must be employed with discernment, preferably alongside one or two of the housekeeping genes identified in this study as internal controls.IMPORTANCEIn our study, we focused on identifying stable reference genes for quantitative real-time PCR (qRT-PCR) experiments on Y. enterocolitica cultured at different temperatures (22°C and 37°C). After thoroughly evaluating 16 candidate genes, we identified six genes-glnS, nuoB, glmS, gyrB, dnaK, and thrS-as exhibiting stable expression across these temperature conditions, making them ideal reference genes for Y. enterocolitica studies. This discovery is crucial for ensuring the accuracy and reliability of qRT-PCR data, as the choice of appropriate reference genes is key to normalizing expression data and minimizing experimental variability. Importantly, our research extended beyond bioinformatics analysis by incorporating validation with clinical strains, bridging the gap between theoretical predictions and practical application. This approach not only underscores the robustness and reliability of our findings but also directly addresses the critical need for experimental validation in the field. By providing a set of validated, stably expressed reference genes, our work offers valuable guidance for designing experiments involving Y. enterocolitica, enhancing the reliability of research outcomes, and advancing our understanding of this significant pathogen. </div> <a href="javascript:ShowArticleAbstract(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Yersinia+enterocolitica%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Yersinia enterocolitica</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22housekeeping+gene%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">housekeeping gene</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22qRT-PCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">qRT-PCR</a></li></ul> <a href="javascript:ShowArticleKeywords(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Yersinia+enterocolitica%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Yersinia enterocolitica/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Essential%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Essential/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Temperature%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Temperature</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RNA%2c+Ribosomal%2c+16S%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RNA, Ribosomal, 16S/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Yersinia+Infections%2fmicrobiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Yersinia Infections/microbiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bacterial+Proteins%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bacterial Proteins/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bacterial+Proteins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bacterial Proteins/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Feces%2fmicrobiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Feces/microbiology</a></li></ul> <a href="javascript:ShowArticleMeSH(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22MOST+%7c+National+Natural+Science+Foundation+of+China+(NSFC)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">82002205 MOST | National Natural Science Foundation of China (NSFC)</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22China+Postdoctoral+Science+Foundation+(China+Postdoctoral+Foundation+Project)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">2019M651802 China Postdoctoral Science Foundation (China Postdoctoral Foundation Project)</a></li></ul> <a href="javascript:ShowArticleGrant(5);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow6"> <td style="min-width: 40px; text-align: center;"> 6 </td> <td> <div id="citation6" class="article-citation"> <b>Pandita S</b>, Alam H, Shivhare R, Singh M, Singh S, Mishra G, Verma PC. Selection and validation of reference genes for quantitative expression analysis of regeneration-related genes in Cheilomenes sexmaculata by real-time qRT-PCR. <em class='incite-journal-name' onclick='ShowInCiteJournal(17395);'>Mol Biol Rep</em> 2024;<b>51</b>:1118. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39495376' target='_blank'>39495376</a> DOI: <a href='https://dx.doi.org/10.1007/s11033-024-10062-1' target='_blank'>10.1007/s11033-024-10062-1</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s11033-024-10062-1','39495376', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(6);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(6);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(6);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s11033-024-10062-1' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17395);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 09/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/24/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv6" value="10.1007/s11033-024-10062-1" /> <div style="display: none" id="articleAbstract6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Regeneration is a fascinating phenomenon that has intrigued scientists for a long time. Cheilomenes sexmaculata (Fabricius), a zig-zag ladybird beetle, possesses a high capacity for limb regeneration. The molecular mechanics of the zig-zag ladybird beetle are under-explored. Current research trends are focused on uncovering functional genes associated with limb regeneration. Most of these investigations involve quantitative real-time PCR (qRT-PCR) for their rapid and accurate analysis of gene expression levels. Hence, a stable and suitable reference gene is required to normalize the gene expression data. </div><div class="abstract-label">METHODS AND RESULTS</div><div class="abstract-content">In this study, five housekeeping genes were selected from the transcriptomics data (in-house unpublished data) of C. sexmaculata (Fabricius). The expression stabilities of the selected genes were evaluated under different time intervals post-amputation using geNorm, normFinder, and refFinder software. Actin was revealed to be the most stable housekeeping gene, along with elongation factor 2 and glyceraldehyde-3-phosphate dehydrogenase. A target gene named engrailed (an important segment-forming gene) was used to validate the selected reference genes. The expression levels were found to be consistent with the transcriptomics results. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">According to our study, actin, along with elongation factor 2 and glyceraldehyde-3-phosphate dehydrogenase, serve as the most stable reference genes and are suitable for regeneration-related research. This study is a groundbreaking effort to identify the most stable reference gene for limb regeneration in C. sexmaculata (Fabricius), and the findings can be applied to other related insect species. </div> <a href="javascript:ShowArticleAbstract(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22%5cn++++++++++++++++++++++++Cheilomenes+sexmaculata%5cn+++++++++++++++++++++%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank"> Cheilomenes sexmaculata </a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22GeNorm%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">GeNorm</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NormFinder%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NormFinder</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RefFinder%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RefFinder</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+genes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference genes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Regeneration%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Regeneration</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22qRT-PCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">qRT-PCR</a></li></ul> <a href="javascript:ShowArticleKeywords(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Coleoptera%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Coleoptera/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Coleoptera%2fphysiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Coleoptera/physiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Regeneration%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Regeneration/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Essential%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Essential/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcriptome%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcriptome/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Insect%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Insect/genetics</a></li></ul> <a href="javascript:ShowArticleMeSH(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(6);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow7"> <td style="min-width: 40px; text-align: center;"> 7 </td> <td> <div id="citation7" class="article-citation"> <b>Mack T</b>, Gianferri T, Niedermayer A, Debatin KM, Meyer LH, Muench V. Benchmarking miRNA reference genes in B-cell precursor acute lymphoblastic leukemia. <em class='incite-journal-name' onclick='ShowInCiteJournal(20954);'>Sci Rep</em> 2024;<b>14</b>:26390. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39488607' target='_blank'>39488607</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531470' target='_blank'>PMC11531470</a> DOI: <a href='https://dx.doi.org/10.1038/s41598-024-77733-8' target='_blank'>10.1038/s41598-024-77733-8</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1038/s41598-024-77733-8','39488607', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(7);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(7);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(7);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(7);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1038/s41598-024-77733-8' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(20954);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/24/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/04/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv7" value="10.1038/s41598-024-77733-8" /> <div style="display: none" id="articleAbstract7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">MicroRNAs (miRNAs) play dual roles in acute lymphoblastic leukemia (ALL) as both tumor suppressors and oncogenes, and miRNA expression profiles can be used for patient risk stratification. Precise assessment of miRNA levels is crucial for understanding their role and function in gene regulation. Quantitative real-time polymerase chain reaction (qPCR) is a reliable, rapid, and cost-effective method for analyzing miRNA expression, assuming that appropriate normalization to stable references is performed to ensure valid data. In this study, we evaluated the stability of six commonly used miRNA references (5sRNA, SNORD44, RNU6, RNU1A1, miR-103a-3p, and miR-532-5p) across nine B-cell precursor (BCP) ALL cell lines, 22 patient-derived xenograft (PDX) BCP ALL samples from different organ compartments of leukemia bearing mice, and peripheral blood mononuclear cells (PBMCs) from six healthy donors. We used four different algorithms (Normfinder, ∆CT, geNorm, and BestKeeper) to assess the most stably expressed reference across all samples. Moreover, we validated our data in an additional set of 13 PDX ALL samples and six healthy controls, identifying miR-103a-3p and miR-532-5p as the most stable references for miRNA normalization in BCP ALL studies. Additionally, we demonstrated the critical importance of using a stable reference to accurately interpret miRNA data. </div> <a href="javascript:ShowArticleAbstract(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22mirnas%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">mirnas</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22acute+lymphocytic+leukaemia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">acute lymphocytic leukaemia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22cancer+models%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">cancer models</a></li></ul> <a href="javascript:ShowArticleKeywords(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22MicroRNAs%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MicroRNAs/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Precursor+B-Cell+Lymphoblastic+Leukemia-Lymphoma%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cell+Line%2c+Tumor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cell Line, Tumor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Regulation%2c+Leukemic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Regulation, Leukemic</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li></ul> <a href="javascript:ShowArticleMeSH(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Universit%c3%a4tsklinikum+Ulm+(8941)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Universitätsklinikum Ulm (8941)</a></li></ul> <a href="javascript:ShowArticleGrant(7);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow8"> <td style="min-width: 40px; text-align: center;"> 8 </td> <td> <div id="citation8" class="article-citation"> <b>Juutinen A</b>, Tiwari A, Hokajärvi AM, Luomala O, Kolehmainen A, Nurmi E, Salmivirta E, Pitkänen T, Lipponen A. The effects of RT-qPCR standards on reproducibility and comparability in monitoring SARS-CoV-2 levels in wastewater. <em class='incite-journal-name' onclick='ShowInCiteJournal(20954);'>Sci Rep</em> 2024;<b>14</b>:25582. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39462074' target='_blank'>39462074</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11513023' target='_blank'>PMC11513023</a> DOI: <a href='https://dx.doi.org/10.1038/s41598-024-77155-6' target='_blank'>10.1038/s41598-024-77155-6</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1038/s41598-024-77155-6','39462074', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(8);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(8);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(8);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1038/s41598-024-77155-6' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(20954);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/28/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv8" value="10.1038/s41598-024-77155-6" /> <div style="display: none" id="articleAbstract8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Reverse transcription-quantitative PCR (RT-qPCR) is widely used for monitoring viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in wastewater. Various materials, including plasmid DNA, synthetic nucleic acids, PCR amplicons, genomic DNA, and cDNA, are currently used for SARS-CoV-2 quantification by generating standard curves. We assessed three common standards on quantifying SARS-CoV-2 RNA across nine wastewater treatment plants in Finland, as part of the national wastewater surveillance effort. We pairwise compared RT-qPCR results from 148 wastewater samples, using both IDT (#10006625, IDT, USA) and CODEX standards (#SC2-RNAC-1100, CODEX DNA), and 179 samples using both IDT and EURM019 standards (#EURM-019, European Commission, Joint Research Centre) in our assessment. Amongst the tested standards, the CODEX standard consistently yielded more stable results than either the IDT or EURM019 standards. We found that SARS-CoV-2 levels were higher with the IDT standard (4.36 Log10 GC/100 mL) compared to the CODEX standard (4.05 Log10 GC/100 mL). Similarly, quantification using the IDT standard was higher (5.27 Log10 GC/100 mL) than values obtained with the EURM019 (4.81 Log10 GC/100 mL). SARS-CoV-2 RNA quantified with IDT and CODEX standards exhibited stronger concordance (Spearman's correlation rho median of 0.79) compared to those quantified with IDT and EURM019 standards (rho median of 0.59). This study highlights the significant impact of standard material selection on SARS-CoV-2 RNA quantification, emphasizing the need for harmonization in standard material. </div> <a href="javascript:ShowArticleAbstract(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-time+quantitative+PCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-time quantitative PCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SARS-CoV-2%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SARS-CoV-2</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Standard+control%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Standard control</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Wastewater+surveillance%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Wastewater surveillance</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Wastewater-based+epidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Wastewater-based epidemiology</a></li></ul> <a href="javascript:ShowArticleKeywords(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Wastewater%2fvirology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Wastewater/virology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SARS-CoV-2%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SARS-CoV-2/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SARS-CoV-2%2fisolation+%26amp%3b+purification%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SARS-CoV-2/isolation & purification</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RNA%2c+Viral%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RNA, Viral/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RNA%2c+Viral%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RNA, Viral/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%2fvirology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19/virology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reproducibility+of+Results%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reproducibility of Results</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Finland%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Finland</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reverse+Transcriptase+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reverse Transcriptase Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reverse+Transcriptase+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reverse Transcriptase Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li></ul> <a href="javascript:ShowArticleMeSH(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(8);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow9"> <td style="min-width: 40px; text-align: center;"> 9 </td> <td> <div id="citation9" class="article-citation"> <b>Tan L</b>, Lu L, Sun W, Zhang X, Liu Y, Xiang Y, Yan H. Identification and validation of qRT-PCR reference genes for analyzing grape infection with gray mold. <em class='incite-journal-name' onclick='ShowInCiteJournal(3935);'>BMC Genomics</em> 2024;<b>25</b>:997. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39448910' target='_blank'>39448910</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11515470' target='_blank'>PMC11515470</a> DOI: <a href='https://dx.doi.org/10.1186/s12864-024-10889-9' target='_blank'>10.1186/s12864-024-10889-9</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1186/s12864-024-10889-9','39448910', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(9);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(9);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(9);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(9);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1186/s12864-024-10889-9' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3935);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/26/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv9" value="10.1186/s12864-024-10889-9" /> <div style="display: none" id="articleAbstract9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Grapes are highly valued for their nutritional and economic benefits, and have been widely studied for their biological attributes such as fruit development, quality formation, and stress resistance. One significant threat to grape quality is gray mold, caused by Botrytis cinerea, which can infect the flowers, fruits, leaves, and stems. The quantitative real-time PCR (qRT-PCR), known for its high sensitivity and quantitative accuracy, is an essential tool for analyzing gene expression related to the pathogenesis of gray mold, thereby providing deeper insights into the disease. </div><div class="abstract-label">RESULT</div><div class="abstract-content">In this study, we aim to identify stable internal reference genes crucial for accurate gene expression analysis via qRT-PCR. Utilizing transcriptome data from grapes under various disease stresses, we identified twelve candidate reference genes with consistently high expression levels. The stability of these genes was assessed through delta-CT, geNorm, NormFinder, BestKeeper, and RefFinder analyses after establishing the cycling thresholds (Ct) in different grape varieties treated with Botrytis cinerea. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">Our findings reveal that VIT-17s0000g02750 and VIT-06s0004g04280 exhibit stable expression and are suitable as new reference genes. This foundational work supports further research into the molecular mechanisms of grape biological processes. </div> <a href="javascript:ShowArticleAbstract(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Grape+gray+mold%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Grape gray mold</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22QRT-PCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">QRT-PCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+genes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference genes</a></li></ul> <a href="javascript:ShowArticleKeywords(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vitis%2fmicrobiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vitis/microbiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vitis%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vitis/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Botrytis%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Botrytis/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plant+Diseases%2fmicrobiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plant Diseases/microbiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plant+Diseases%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plant Diseases/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Plant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Plant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Regulation%2c+Plant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Regulation, Plant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcriptome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcriptome</a></li></ul> <a href="javascript:ShowArticleMeSH(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant9" class="article-abstract"> <b style="display: block; 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text-align: center;"> 10 </td> <td> <div id="citation10" class="article-citation"> <b>Qiu Y</b>, Bai Y, Wang W, Wang Q, Chen S, Zhang J. Reference Gene Selection for RT-qPCR Normalization in <i>Toxoplasma gondii</i> Exposed to Broxaldine. <em class='incite-journal-name' onclick='ShowInCiteJournal(11724);'>Int J Mol Sci</em> 2024;<b>25</b>:11403. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39518956' target='_blank'>39518956</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11546418' target='_blank'>PMC11546418</a> DOI: <a href='https://dx.doi.org/10.3390/ijms252111403' target='_blank'>10.3390/ijms252111403</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/ijms252111403','39518956', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(10);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(10);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(10);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(10);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/ijms252111403' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.3390/ijms252111403');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11724);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 09/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/16/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv10" value="10.3390/ijms252111403" /> <div style="display: none" id="articleAbstract10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Reverse transcription-quantitative real-time polymerase chain reaction (RT-qPCR) is widely used to accurately assess target gene expression. Evaluating gene expression requires the selection of appropriate reference genes. To identify reliable reference genes for Toxoplasma gondii (T. gondii) under varying concentrations of broxaldine (BRO), we employed the ΔCt method, BestKeeper, NormFinder, GeNorm, and the comprehensive web-based platform RefFinder to assess the expression stability of ten candidate reference genes in T. gondii. Herein, our findings reveal that the stability of these candidate reference genes is influenced by different experimental conditions. Under normal conditions, the most stable genes were TGME49_205470 and TGME49_226020. However, the most stable genes differed when BRO concentrations were at 1, 2, and 4 μg/mL. Across all samples, TGME49_247220 and TGME49_235930 were identified as the most stable reference genes. Moreover, we also confirmed the stability of TGME49_247220 and TGME49_235930 as reference genes through RT-qPCR assays. The present study provides a foundation for applying the RT-qPCR method to investigate target gene expression following BRO treatment in T. gondii. </div> <a href="javascript:ShowArticleAbstract(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RT-qPCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RT-qPCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Toxoplasma+gondii%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Toxoplasma gondii</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22broxaldine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">broxaldine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22gene+stability%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">gene stability</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22reference+genes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">reference genes</a></li></ul> <a href="javascript:ShowArticleKeywords(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Toxoplasma%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Toxoplasma/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Toxoplasma%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Toxoplasma/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Protozoan%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Protozoan</a></li></ul> <a href="javascript:ShowArticleMeSH(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22the+Earmarked+Fund+for+China+Agriculture+Research+System%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">grant CARS-37 the Earmarked Fund for China Agriculture Research System</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22the+Innovation+Project+of+Chinese+Academy+of+Agricultural+Sciences%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">grant 25-LZIHPS-05 the Innovation Project of Chinese Academy of Agricultural Sciences</a></li></ul> <a href="javascript:ShowArticleGrant(10);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow11"> <td style="min-width: 40px; text-align: center;"> 11 </td> <td> <div id="citation11" class="article-citation"> <b>Jäger R</b>. Genomic Multicopy Loci Targeted by Current Forensic Quantitative PCR Assays. <em class='incite-journal-name' onclick='ShowInCiteJournal(9760);'>Genes (Basel)</em> 2024;<b>15</b>:1299. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39457423' target='_blank'>39457423</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11507060' target='_blank'>PMC11507060</a> DOI: <a href='https://dx.doi.org/10.3390/genes15101299' target='_blank'>10.3390/genes15101299</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/genes15101299','39457423', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(11);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(11);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(11);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/genes15101299' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(9760);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 09/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/28/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv11" value="10.3390/genes15101299" /> <div style="display: none" id="articleAbstract11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Modern forensic DNA quantitation assays provide information on the suitability of a DNA extract for a particular type of analysis, on the amount of sample to put into the analysis in order to yield an optimal (or best possible) result, and on the requirement for optional steps to improve the analysis. To achieve a high sensitivity and specificity, these assays are based on quantitative PCR (qPCR) and analyze target DNA loci that are present in multiple copies distributed across the genome. These target loci allow the determination of the amount of DNA, the degree of DNA degradation, and the proportion of DNA from male contributors. In addition, internal control DNA of a known amount is analyzed in order to inform about the presence of PCR inhibitors. These assays are nowadays provided as commercial kits that have been technically validated and are compatible with common qPCR instruments. In this review, the principles of forensic qPCR assays will be explained, followed by information on the nature of DNA loci targeted by modern forensic qPCR assays. Finally, we critically draw attention to the current trend of manufacturers not to disclose the exact nature of the target loci of their commercial kits. </div> <a href="javascript:ShowArticleAbstract(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alu%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alu</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA+degradation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA degradation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plexor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plexor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22STR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">STR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22TaqMan%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">TaqMan</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Y+chromosome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Y chromosome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22forensic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">forensic</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22qPCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">qPCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22quantitative+PCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">quantitative PCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22real-time+PCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">real-time PCR</a></li></ul> <a href="javascript:ShowArticleKeywords(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Forensic+Genetics%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Forensic Genetics/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genetic+Loci%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genetic Loci</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22DNA+Fingerprinting%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DNA Fingerprinting/methods</a></li></ul> <a href="javascript:ShowArticleMeSH(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(11);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow12"> <td style="min-width: 40px; text-align: center;"> 12 </td> <td> <div id="citation12" class="article-citation"> <b>Bird P</b>, Mills J, Johnson R, McIntyre M, Valadez A. Understanding the Complexity of Microbiology Method Validation to Meet State-Specific Requirements for Cannabis. <em class='incite-journal-name' onclick='ShowInCiteJournal(13120);'>J AOAC Int</em> 2024;<b>107</b>:839-856. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38831615' target='_blank'>38831615</a> DOI: <a href='https://dx.doi.org/10.1093/jaoacint/qsae046' target='_blank'>10.1093/jaoacint/qsae046</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1093/jaoacint/qsae046','38831615', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(12);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(12);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(12);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1093/jaoacint/qsae046' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(13120);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/27/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 11/21/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 05/14/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 06/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv12" value="10.1093/jaoacint/qsae046" /> <div style="display: none" id="articleAbstract12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Federal legislation still prohibits the cultivation, sale, and consumption of cultivars of delta 9-tetrahydrocannabinol cannabis (>0.3%); however, as of November 2022, 39 states have legalized cannabis and cannabis derived products for medicinal consumption and 21 states have legalized for adult-use consumption. This state-by-state approach has produced a patch work of regulations that multi-state operators (MSOs) must learn to navigate. Furthermore, cannabis laboratories often lack the space and skill needed to perform method validations, adding another layer of complexity. While these barriers exist, it is paramount for MSOs to demonstrate the fitness of purpose of their methods. </div><div class="abstract-label">OBJECTIVE</div><div class="abstract-content">This review presents the complexity that an MSO navigated in developing microbiology method validation study designs for two proprietary real-time PCR (RT-PCR) assays to meet four state (California, Florida, Michigan, and Oklahoma) testing requirements. The testing in each state was conducted in addition to certification of the assays through the AOAC Performance Tested MethodSM (PTM) program. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Matrix studies were conducted targeting three analytes (Aspergillus spp., Salmonella spp., and Shiga toxin-producing Escherichia coli) as directed by the state regulatory authorities. For California, inclusivity and exclusivity studies were performed. The number of contamination levels, test portion replicates, and total target organisms evaluated varied by state. Culture confirmation was not performed outside of the AOAC PTM studies. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Data from each study was collected, summarized, and provided to the state regulatory agencies. Review of the data consisted of identifying discrepant results and verification of controls. After review, each assay was certified for use in the respective state. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">Requirements from each of the states demonstrate the complexities MSOs face and emphasize the need for a more standardized approach to streamline acceptance of alternative methods. </div><div class="abstract-label">HIGHLIGHTS</div><div class="abstract-content">While varying state regulations can be complex, validation studies performed for the candidate methods have led to adoption across 31 states. </div> <a href="javascript:ShowArticleAbstract(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <a href="javascript:ShowArticleKeywords(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cannabis%2fmicrobiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cannabis/microbiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22United+States%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">United States</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Validation+Studies+as+Topic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Validation Studies as Topic</a></li></ul> <a href="javascript:ShowArticleMeSH(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22bioM%c3%a9rieux%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">bioMérieux</a></li></ul> <a href="javascript:ShowArticleGrant(12);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow13"> <td style="min-width: 40px; text-align: center;"> 13 </td> <td> <div id="citation13" class="article-citation"> <b>Martins AWS</b>, Nunes LS, Blödorn EB, Dellagostin EN, Silveira TLR, Collares GL, Domingues WB, Pinhal D, Remião MH, Campos VF. Selection of references for quantitative real-time PCR analysis of microRNAs in Nile tilapia (Oreochromis niloticus) under osmotic stress. <em class='incite-journal-name' onclick='ShowInCiteJournal(169101);'>Comp Biochem Physiol B Biochem Mol Biol</em> 2024;<b>274</b>:111010. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39094679' target='_blank'>39094679</a> DOI: <a href='https://dx.doi.org/10.1016/j.cbpb.2024.111010' target='_blank'>10.1016/j.cbpb.2024.111010</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.cbpb.2024.111010','39094679', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(13);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(13);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(13);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.cbpb.2024.111010' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(169101);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/29/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/04/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv13" value="10.1016/j.cbpb.2024.111010" /> <div style="display: none" id="articleAbstract13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">MicroRNAs play crucial regulatory roles in various aspects of development and physiology, including environmental adaptation and stress responses in teleosts. RT-qPCR is the most commonly used method for studying microRNA expression, with the accuracy and reliability of results depending on the use of an appropriate reference gene for normalization. This study aimed to evaluate seven miRNAs (U6, Let-7a, miR-23a, miR-25-3, miR-103, miR-99-5, and miR-455) expression stability in different tissues of Nile tilapia subjected to osmotic stress. Fish were divided into two groups: a control and an experimental group, raised in 0 and 12 ppt salinity water respectively. After 21 days, brain, gills, liver, and posterior intestine were collected for analysis. Different mathematical algorithms (geNorm, NormFinder, BestKeeper, and the comparative ΔCt method) were employed to identify the most suitable reference miRNAs. The results indicate that the miR-455/miR-23a combination is a robust reference for normalizing miRNA expression levels in studies of osmotic stress responses in Nile tilapia. The stability of miRNA expression can vary depending on specific stress conditions and biological processes, underscoring the necessity of selecting appropriate normalizing miRNAs for each experimental context. This study identifies reliable reference genes for future RT-qPCR analyses of miRNA expression, thereby enhancing our understanding of molecular responses in fish to environmental challenges. These insights are fundamental to the development of new technologies for the improved management and sustainability of aquaculture practices. </div> <a href="javascript:ShowArticleAbstract(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chronic+stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chronic stress</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+expression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene expression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+miRNA%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference miRNA</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Salinity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Salinity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22qPCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">qPCR</a></li></ul> <a href="javascript:ShowArticleKeywords(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22MicroRNAs%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MicroRNAs/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22MicroRNAs%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">MicroRNAs/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cichlids%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cichlids/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cichlids%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cichlids/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Osmotic+Pressure%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Osmotic Pressure</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li></ul> <a href="javascript:ShowArticleMeSH(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(13);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow14"> <td style="min-width: 40px; text-align: center;"> 14 </td> <td> <div id="citation14" class="article-citation"> <b>Carvalho A</b>, Crisóstomo C, Leal F, Lima-Brito J. Selection of Reference Genes and <i>HSP17.9A</i> Expression Profiling in Heat-Stressed Grapevine Varieties. <em class='incite-journal-name' onclick='ShowInCiteJournal(9760);'>Genes (Basel)</em> 2024;<b>15</b>:1283. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39457407' target='_blank'>39457407</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11507026' target='_blank'>PMC11507026</a> DOI: <a href='https://dx.doi.org/10.3390/genes15101283' target='_blank'>10.3390/genes15101283</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/genes15101283','39457407', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(14);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(14);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(14);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(14);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/genes15101283' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(9760);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 09/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/28/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv14" value="10.3390/genes15101283" /> <div style="display: none" id="articleAbstract14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">"Touriga Franca" (TF) and "Touriga Nacional" (TN) are grapevine varieties cultivated in the 'Douro Superior' subregion (Northern Portugal) that experience stressful environmental conditions during the summer. </div><div class="abstract-label">OBJECTIVES</div><div class="abstract-content">Aiming to profile the expression of stress-responsive genes by quantitative real-time PCR (qPCR) in TF and TN plants growing naturally, three candidate reference genes were first tested under controlled conditions. </div><div class="abstract-label">METHODS</div><div class="abstract-content">To simulate a summer's day, TF and TN in vitro plants were exposed to 32 °C-3 h (heat acclimation) and 42 °C-1 h (severe heat stress, HS) followed by two recovery periods (32 °C-3 h and 24 °C-24 h). Leaf samples were collected at the end of each phase. Control plants were kept at 24 °C. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Among the candidate reference genes, the UBC and VAG pair showed the highest stability. The suitability of these genes for qPCR was validated by heat shock protein 17.9A (HSP17.9A) gene profiling. The HSP17.9A expression was up-regulated in both varieties and all experimental phases except in TF control plants. TN showed the highest HSP17.9A relative expression ratio after severe HS. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">TN responded faster than TF to the induced heat shocks. The UBC, VAG, and HSP17.9A genes revealed to be suitable for further qPCR assays in TF and TN grapevine varieties. </div> <a href="javascript:ShowArticleAbstract(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ubiquitin-conjugating+enzyme+(UBC)+gene%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ubiquitin-conjugating enzyme (UBC) gene</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vacuolar+ATPase+subunit+G+(VAG)+gene%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vacuolar ATPase subunit G (VAG) gene</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22gene+expression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">gene expression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22heat+shock+protein%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">heat shock protein</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22in+vitro+culture%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">in vitro culture</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22quantitative+real-time+PCR+(qPCR)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">quantitative real-time PCR (qPCR)</a></li></ul> <a href="javascript:ShowArticleKeywords(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Vitis%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Vitis/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heat-Shock+Response%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heat-Shock Response/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plant+Proteins%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plant Proteins/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Regulation%2c+Plant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Regulation, Plant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Heat-Shock+Proteins%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Heat-Shock Proteins/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plant+Leaves%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plant Leaves/genetics</a></li></ul> <a href="javascript:ShowArticleMeSH(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Portugal+2020+under+the+project+INNOVINE%26WINE+-+Vineyard+and+Wine+Innovation+Platform+(NORTE-01-0145-FEDER-000038%2c+research+line+Viticulture%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">BPD/UTAD/INNOVINE&WINE/593/2016 Portugal 2020 under the project INNOVINE&WINE - Vineyard and Wine Innovation Platform (NORTE-01-0145-FEDER-000038, research line Viticulture</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Funda%c3%a7%c3%a3o+para+a+Ci%c3%aancia+e+a+Tecnologia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">UIDB/04033/2020 (https://doi.org/10.54499/UIDB/04033/2020) Fundação para a Ciência e a Tecnologia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Funda%c3%a7%c3%a3o+para+a+Ci%c3%aancia+e+a+Tecnologia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">DL 57/2016/CP1378/CT0003 (doi:10.54499/DL57/2016/CP1378/CT0003) Fundação para a Ciência e a Tecnologia</a></li></ul> <a href="javascript:ShowArticleGrant(14);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow15"> <td style="min-width: 40px; text-align: center;"> 15 </td> <td> <div id="citation15" class="article-citation"> <b>de Souza MR</b>, Araújo IP, da Costa Arruda W, Lima AA, Ságio SA, Chalfun-Junior A, Barreto HG. RGeasy: a reference gene analysis tool for gene expression studies via RT-qPCR. <em class='incite-journal-name' onclick='ShowInCiteJournal(3935);'>BMC Genomics</em> 2024;<b>25</b>:907. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39350049' target='_blank'>39350049</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441100' target='_blank'>PMC11441100</a> DOI: <a href='https://dx.doi.org/10.1186/s12864-024-10808-y' target='_blank'>10.1186/s12864-024-10808-y</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1186/s12864-024-10808-y','39350049', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(15);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(15);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(15);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(15);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1186/s12864-024-10808-y' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rcastoragev2.blob.core.windows.net/a596d8b317b2eacf06302e236f6c8040/12864_2024_Article_10808.PMC11441100.pdf' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.1186/s12864-024-10808-y');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3935);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 12/12/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/04/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv15" value="10.1186/s12864-024-10808-y" /> <div style="display: none" id="articleAbstract15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Gene expression through RT-qPCR can be performed by the relative quantification method, which requires the expression normalization through reference genes. Therefore, it is essential to validate, experimentally, the candidate reference genes. Thus, although there are several studies that are performed to identify the most stable reference genes, most them validate genes for very specific conditions, not exploring the whole potential of the research since not all possible combinations of treatments and/or conditions of the study are explored. For this reason, new experiments must be conducted by researchers that have interest in analyzing gene expression of treatments and/or conditions present, but not explored, in these studies. Here, we present the RGeasy tool, which aims to facilitate the selection of reference genes, allowing the user to choose genes for a greater number of combinations of treatments/conditions, compared to the ones present in the original articles, through just a few clicks. RGeasy was validated with RT-qPCR data from gene expression studies performed in two coffee species, Coffea arabica and Coffea canephora, and it can be used for any animal, plant or microorganism species. In addition to displaying a rank of the most stable reference genes for each condition or treatment, the user also has access to the primer pairs for the selected reference genes. </div> <a href="javascript:ShowArticleAbstract(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endogenous+genes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endogenous genes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Normalization%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Normalization</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Relative+expression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Relative expression</a></li></ul> <a href="javascript:ShowArticleKeywords(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Software%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Software</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Plant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Plant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Coffea%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Coffea/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Regulation%2c+Plant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Regulation, Plant</a></li></ul> <a href="javascript:ShowArticleMeSH(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Coordena%c3%a7%c3%a3o+de+Aperfei%c3%a7oamento+de+Pessoal+de+N%c3%advel+Superior%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Finance Code 001 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior</a></li></ul> <a href="javascript:ShowArticleGrant(15);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow16"> <td style="min-width: 40px; text-align: center;"> 16 </td> <td> <div id="citation16" class="article-citation"> <b>Bunde TT</b>, Pedra ACK, de Oliveira NR, Dellagostin OA, Bohn TLO. A systematic review on the selection of reference genes for gene expression studies in rodents: are the classics the best choice? <em class='incite-journal-name' onclick='ShowInCiteJournal(17395);'>Mol Biol Rep</em> 2024;<b>51</b>:1017. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39327364' target='_blank'>39327364</a> DOI: <a href='https://dx.doi.org/10.1007/s11033-024-09950-3' target='_blank'>10.1007/s11033-024-09950-3</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s11033-024-09950-3','39327364', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(16);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(16);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(16);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s11033-024-09950-3' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17395);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/14/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/28/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv16" value="10.1007/s11033-024-09950-3" /> <div style="display: none" id="articleAbstract16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Rodents are commonly used as animal models in studies investigating various experimental conditions, often requiring gene expression analysis. Quantitative real-time reverse transcription PCR (RT-qPCR) is the most widely used tool to quantify target gene expression levels under different experimental conditions in various biological samples. Relative normalization with reference genes is a crucial step in RT-qPCR to obtain reliable quantification results. In this work, the main reference genes used in gene expression studies among the three rodents commonly employed in scientific research-hamster, rat, and mouse-are analyzed and described. An individual literature search for each rodent was conducted using specific search terms in three databases: PubMed, Scopus, and Web of Science. A total of 157 articles were selected (rats = 73, mice = 79, and hamsters = 5), identifying various reference genes. The most commonly used reference genes were analyzed according to each rodent, sample type, and experimental condition evaluated, revealing a great variability in the stability of each gene across different samples and conditions. Classic genes, which are expected to be stably expressed in both samples and conditions analyzed, demonstrated greater variability, corroborating existing concerns about the use of these genes. Therefore, this review provides important insights for researchers seeking to identify suitable reference genes for their validation studies in rodents. </div> <a href="javascript:ShowArticleAbstract(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hamster%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hamster</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Housekeeping+genes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Housekeeping genes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mouse%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mouse</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RT-qPCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RT-qPCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rat%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rat</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Relative+quantification%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Relative quantification</a></li></ul> <a href="javascript:ShowArticleKeywords(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rodentia%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rodentia/genetics</a></li></ul> <a href="javascript:ShowArticleMeSH(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(16);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow17"> <td style="min-width: 40px; text-align: center;"> 17 </td> <td> <div id="citation17" class="article-citation"> <b>Scarpaleggia M</b>, Garzillo G, Lucente M, Fraccalvieri C, Randazzo N, Massaro E, Galano B, Ricucci V, Bruzzone B, Domnich A. Diagnostic Accuracy of Five Molecular Assays for the Detection of Dengue Virus. <em>MEDICINA (KAUNAS, LITHUANIA)</em> 2024;<b>60</b>:1557. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39336598' target='_blank'>39336598</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11434457' target='_blank'>PMC11434457</a> DOI: <a href='https://dx.doi.org/10.3390/medicina60091557' target='_blank'>10.3390/medicina60091557</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/medicina60091557','39336598', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(17);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(17);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(17);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/medicina60091557' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/21/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/30/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv17" value="10.3390/medicina60091557" /> <div style="display: none" id="articleAbstract17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Background and Objectives: The steady spread of dengue virus (DENV) poses a profound public health threat worldwide. Reverse transcription real-time polymerase chain reaction (RT2-PCR) has been increasingly recognized as a reference method for the diagnosis of acute dengue infection. The goal of this study was to assess the diagnostic accuracy of five different RT2-PCR kits for the detection of DENV in a historically processed set of sera samples. Materials and Methods: In this retrospective study, 25 sera samples from routinely processed unique adult patients with a known DENV status (previously tested in both molecular and serological assays) were tested in parallel using four conventional (RealStar Dengue PCR Kit 3.0, Clonit'ngo Zika, Dengue & Chikungunya, BioPerfectus Zika Virus/Dengue Virus/Chikungunya Virus Real Time PCR Kit and Novaplex Tropical fever virus) and one sample-to-result (STANDARD M10 Arbovirus Panel) RT2-PCR assays. Additionally, an end-point dilution analysis was conducted in quintuplicate on six serial dilutions of an RNA preparation obtained from a culture-grown DENV serotype 1 strain for a total of 150 tests. Results: The overall accuracy of the evaluated tests ranged from 84% to 100%. In particular, the sensitivity of three conventional RT2-PCR assays (RealStar, Clonit'ngo and Novaplex) was 100% (95% CI: 79.6-100%), while it was lower (73.3%; 95% CI: 48.1-89.1%) for the BioPerfectus kit. The sample-to-result STANDARD M10 panel performed comparatively well, showing a sensitivity of 92.9% (95% CI: 68.5-98.7%). No false positive results were registered in any assay. The end-point dilution analysis suggested that the RealStar kit had the lowest limit of detection. Conclusions: Available RT2-PCR kits for the detection of DENV are highly specific and generally sensitive and, therefore, their implementation in diagnostic pathways is advisable. </div> <a href="javascript:ShowArticleAbstract(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RT2-PCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RT2-PCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22arboviruses%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">arboviruses</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22dengue%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">dengue</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22diagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22diagnostic+accuracy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">diagnostic accuracy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22molecular+diagnostics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">molecular diagnostics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22multiplex+RT2-PCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">multiplex RT2-PCR</a></li></ul> <a href="javascript:ShowArticleKeywords(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dengue+Virus%2fisolation+%26amp%3b+purification%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dengue Virus/isolation & purification</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dengue+Virus%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dengue Virus/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retrospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retrospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dengue%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dengue/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sensitivity+and+Specificity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sensitivity and Specificity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li></ul> <a href="javascript:ShowArticleMeSH(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(17);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow18"> <td style="min-width: 40px; text-align: center;"> 18 </td> <td> <div id="citation18" class="article-citation"> <b>Gao R</b>, He W, Zhu WT, Zhao X, Chen C, Wu Y, Wu S, Zhai JW, Liu ZJ. Selection of Reference Genes of Flower Development in <i>Ludisia discolor</i>. <em class='incite-journal-name' onclick='ShowInCiteJournal(9760);'>Genes (Basel)</em> 2024;<b>15</b>:1225. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39336816' target='_blank'>39336816</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11431258' target='_blank'>PMC11431258</a> DOI: <a href='https://dx.doi.org/10.3390/genes15091225' target='_blank'>10.3390/genes15091225</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/genes15091225','39336816', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(18);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(18);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(18);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(18);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/genes15091225' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(9760);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/30/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv18" value="10.3390/genes15091225" /> <div style="display: none" id="articleAbstract18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Background: RT-qPCR is a powerful strategy for recognizing the most appropriate reference genes, which can successfully minimize experimental mistakes through accurate normalization. Ludisia discolor, recognized for its ornamental value, features little, distinctive blossoms with twisted lips and gynostemium showing chiral asymmetry, together with striking blood-red fallen leaves periodically marked with golden blood vessels. Methods and Results: To ensure the accuracy of qRT-PCR, selecting appropriate reference genes for quantifying target gene expression levels is essential. This study aims to identify stable reference genes during the development of L. discolor. In this study, the entire floral buds, including the lips and gynostemium from different development stages, were taken as materials. Based upon the transcriptome information of L. discolor, nine housekeeping genes, ACT, HIS, EF1-α1, EF1-α2, PP2A, UBQ1, UBQ2, UBQ3, and TUB, were selected in this research study as prospect interior referral genes. The expression of these nine genes were found by RT-qPCR and afterwards comprehensively examined by four software options: geNorm, NormFinder, BestKeeper, and ΔCt. The outcomes of the analysis showed that ACT was the most steady gene, which could be the most effective inner referral gene for the expression evaluation of flower advancement in L. discolor. Conclusions: The results of this study will contribute to the molecular biology research of flower development in L. discolor and closely related species. </div> <a href="javascript:ShowArticleAbstract(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ludisia+discolor%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ludisia discolor</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RT-qPCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RT-qPCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22reference+gene%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">reference gene</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22stability+evaluation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">stability evaluation</a></li></ul> <a href="javascript:ShowArticleKeywords(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Flowers%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Flowers/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Flowers%2fgrowth+%26amp%3b+development%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Flowers/growth & development</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Regulation%2c+Plant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Regulation, Plant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Plant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Plant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Essential%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Essential/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Transcriptome%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Transcriptome/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Plant+Proteins%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Plant Proteins/genetics</a></li></ul> <a href="javascript:ShowArticleMeSH(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant18" class="article-abstract"> <b style="display: block; 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text-align: center;"> 19 </td> <td> <div id="citation19" class="article-citation"> <b>Vidal MR</b>, Lasmar LF, Nadai PCF, Oliveira C, Silva DMZA, Foresti F. Selecting reference genes for RT-qPCR studies involving the presence of B chromosomes in Psalidodon (Characiformes, Characidae). <em class='incite-journal-name' onclick='ShowInCiteJournal(17395);'>Mol Biol Rep</em> 2024;<b>51</b>:977. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39259380' target='_blank'>39259380</a> DOI: <a href='https://dx.doi.org/10.1007/s11033-024-09911-w' target='_blank'>10.1007/s11033-024-09911-w</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s11033-024-09911-w','39259380', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(19);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(19);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(19);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(19);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s11033-024-09911-w' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(17395);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/27/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/13/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv19" value="10.1007/s11033-024-09911-w" /> <div style="display: none" id="articleAbstract19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">B chromosomes are extra non-essential elements present in several eukaryotes. Unlike A chromosomes which are essential and present in all individuals of a species, B chromosomes are not necessary for normal functioning of an organism. Formerly regarded as genetically inactive, B chromosomes have been discovered to not only express their own genes, but also to exert influence on gene expression in A chromosomes. Recent studies have shown that, in some Psalidodon (Characiformes, Characidae) species, B chromosomes might be associated with phenotypic effects, such as changes in the reproductive cycle and gene expression. </div><div class="abstract-label">METHODS AND RESULTS</div><div class="abstract-content">In this study, we aimed to establish stable reference genes for RT-qPCR experiments conducted on gonads of three fish species within Psalidodon genus, both in the presence and absence of B chromosomes. The stability of five selected reference genes was assessed using NormFinder, geNorm, BestKeeper, and RefFinder algorithms. We determined ppiaa and pgk1 as the most stable genes in P. fasciatus, whereas ppiaa and hmbsa showed the highest stability in P. bockmanni. For P. paranae, tbp and hprt1 were the most stable genes in females, and ppiaa and hprt1 were the most stable in males. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">We determined the most stable reference genes in gonads of three Psalidodon species considering the presence of B chromosomes. This is the first report of reference gene stability in the genus and provides valuable tools to better understand the effects of B chromosomes at gene expression level. </div> <a href="javascript:ShowArticleAbstract(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22%5cn++++++++++++++++++++++++Astyanax%5cn+++++++++++++++++++++%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank"> Astyanax </a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+expression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene expression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Housekeeping+genes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Housekeeping genes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Supranumerary+chromosome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Supranumerary chromosome</a></li></ul> <a href="javascript:ShowArticleKeywords(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chromosomes%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chromosomes/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gonads%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gonads/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Characidae%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Characidae/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Characiformes%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Characiformes/genetics</a></li></ul> <a href="javascript:ShowArticleMeSH(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant19" class="article-abstract"> <b style="display: block; 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text-align: center;"> 20 </td> <td> <div id="citation20" class="article-citation"> <b>Disha-Ibrahimi S</b>, Drevenšek G, Drevenšek M, Marc J, Žitnik IP. PPIA, HRPT1, and PGK1 genes as the appropriate combination for RT-qPCR normalization in alveolar and femoral bone remodeling in olanzapine-treated rats. <em>ACTA PHARMACEUTICA (ZAGREB, CROATIA)</em> 2024;<b>74</b>:511-524. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39279526' target='_blank'>39279526</a> DOI: <a href='https://dx.doi.org/10.2478/acph-2024-0029' target='_blank'>10.2478/acph-2024-0029</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.2478/acph-2024-0029','39279526', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(20);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(20);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(20);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/18/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv20" value="10.2478/acph-2024-0029" /> <div style="display: none" id="articleAbstract20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Reliable gene expression analysis in bone remodeling studies requires an appropriate selection of internal controls, i.e. stable reference genes for the normalization of quantitative real-time PCR (RT-qPCR), the most common method used for quantifying gene expression measurements. Even the most widely used reference genes can have variable expression under different experimental conditions, or in different tissue types or treatment regimes, so selecting appropriate controls is a key step in ensuring reliable results. The aim of this research was to identify the most stable reference gene(s) for the study of olanzapine modulated bone remodeling in rats. RNA was isolated from the maxillary alveolar and femoral bones of olanzapine or placebo-treated Wistar rats and transcribed to cDNA. The expression of 12 candidate reference genes was assessed by RT-qPCR. Their expressions were analysed using GeNorm, NormFinder, BestKeeper and delta Ct algorithms, and by the comprehensive ranking method. PPIA, HRPT1 and PGK1 were the most stably expres sed reference genes and the combination of the three genes was optimal for normalization. This study is the first to identify the optimal reference genes for research in olanzapine-exposed rats, which serve as a pivotal benchmark for enhancing the accuracy and reliability of future RT-qPCR expression in bone studies. </div> <a href="javascript:ShowArticleAbstract(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RT-qPCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RT-qPCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22alveolar+bone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">alveolar bone</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22olanzapine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">olanzapine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22rat%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">rat</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22reference+genes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">reference genes</a></li></ul> <a href="javascript:ShowArticleKeywords(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Olanzapine%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Olanzapine/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Wistar%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Wistar</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Femur%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Femur/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Femur%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Femur/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bone+Remodeling%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bone Remodeling/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bone+Remodeling%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bone Remodeling/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Phosphoglycerate+Kinase%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Phosphoglycerate Kinase/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reproducibility+of+Results%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reproducibility of Results</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antipsychotic+Agents%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antipsychotic Agents/pharmacology</a></li></ul> <a href="javascript:ShowArticleMeSH(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(20);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow21"> <td style="min-width: 40px; text-align: center;"> 21 </td> <td> <div id="citation21" class="article-citation"> <b>MacLean AR</b>, Gunson R. Automation and standardisation of a quantitative multiplex PCR assay using PCR.Ai. <em class='incite-journal-name' onclick='ShowInCiteJournal(15731);'>J Virol Methods</em> 2024;<b>329</b>:114981. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39004191' target='_blank'>39004191</a> DOI: <a href='https://dx.doi.org/10.1016/j.jviromet.2024.114981' target='_blank'>10.1016/j.jviromet.2024.114981</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jviromet.2024.114981','39004191', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(21);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(21);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(21);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jviromet.2024.114981' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(15731);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 10/17/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 06/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/16/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv21" value="10.1016/j.jviromet.2024.114981" /> <div style="display: none" id="articleAbstract21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">We previously undertook a prospective clinical study to evaluate PCR.Ai's (www.pcr.ai) accuracy and impact when automating the manual data-analysis and quality control steps associated with routine clinical pathogen testing using a non-quantitative multiplex quantitative real-time PCR (qPCR). In this study we demonstrated 100 % concurrence between our manual routine analysis method and PCR.Ai. This paper expands the evaluation of PCR.Ai's (www.pcr.ai) accuracy and impact using a multiplex quantitative real-time PCR (qPCR). </div><div class="abstract-label">OBJECTIVES</div><div class="abstract-content">We evaluated the impact of PCR.Ai when used as the final interpretation/verification step for routine in-house multiplex quantitative qPCR tests for CMV, EBV and adenovirus from blood samples for a total of 1350 interpretations. </div><div class="abstract-label">STUDY DESIGN</div><div class="abstract-content">We compared PCR.Ai to our existing manual interpretation, to determine accuracy and hands on time savings. </div><div class="abstract-label">RESULTS AND CONCLUSIONS</div><div class="abstract-content">There was 100 % concurrence between validated CMV, EBV and adenovirus detection and quantitation by our manual routine analysis method and PCR.Ai. Furthermore, there were significant routine savings with PCR.Ai of 63 minutes/ run. Our conclusion is that for quantitative tests PCR.Ai is a highly accurate time-saving tool that reduces complexity of qPCR analysis and hence the need for specialists and hands-on time. It demonstrated capabilities to enable us to get results out more quickly with lower costs and less risk of errors. </div> <a href="javascript:ShowArticleAbstract(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Multiplex+PCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Multiplex PCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22PCR%3aAi%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">PCR:Ai</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Quantitation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Quantitation</a></li></ul> <a href="javascript:ShowArticleKeywords(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Multiplex+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Multiplex Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Multiplex+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Multiplex Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytomegalovirus%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytomegalovirus/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cytomegalovirus%2fisolation+%26amp%3b+purification%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cytomegalovirus/isolation & purification</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Automation%2c+Laboratory%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Automation, Laboratory/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Automation%2c+Laboratory%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Automation, Laboratory/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Herpesvirus+4%2c+Human%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Herpesvirus 4, Human/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Herpesvirus+4%2c+Human%2fisolation+%26amp%3b+purification%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Herpesvirus 4, Human/isolation & purification</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adenoviridae%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adenoviridae/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adenoviridae%2fisolation+%26amp%3b+purification%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adenoviridae/isolation & purification</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Automation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Automation</a></li></ul> <a href="javascript:ShowArticleMeSH(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(21);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow22"> <td style="min-width: 40px; text-align: center;"> 22 </td> <td> <div id="citation22" class="article-citation"> <b>Rajkhowa S</b>, Sonowal J, Sengar GS, Pegu SR, Deb R, Das PJ, Doley J, Paul S, Gupta VK. Assessment of reference genes for qRT-PCR normalization to elucidate host response to African swine fever infection. <em class='incite-journal-name' onclick='ShowInCiteJournal(4031);'>Braz J Microbiol</em> 2024;<b>55</b>:2943-2952. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38963474' target='_blank'>38963474</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11405621' target='_blank'>PMC11405621</a> DOI: <a href='https://dx.doi.org/10.1007/s42770-024-01439-2' target='_blank'>10.1007/s42770-024-01439-2</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s42770-024-01439-2','38963474', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(22);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(22);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(22);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(22);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s42770-024-01439-2' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(4031);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/24/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/05/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv22" value="10.1007/s42770-024-01439-2" /> <div style="display: none" id="articleAbstract22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Viral infection disrupts the normal regulation of the host gene's expression. In order to normalise the expression of dysregulated host genes upon virus infection, analysis of stable reference housekeeping genes using quantitative real-time-PCR (qRT-PCR) is necessary. In the present study, healthy and African swine fever virus (ASFV) infected porcine tissues were assessed for the expression stability of five widely used housekeeping genes (HPRT1, B2M, 18 S rRNA, PGK1 and H3F3A) as reference genes using standard algorithm. Total RNA from each tissue sample (lymph node, spleen, kidney, heart and liver) from healthy and ASFV-infected pigs was extracted and subsequently cDNA was synthesized, and subjected to qRT-PCR. Stability analysis of reference genes expression was performed using the Comparative delta CT, geNorm, BestKeeper and NormFinder algorithm available at RefFinder for the different groups. Direct Cycle threshold (CT) values of samples were used as an input for the web-based tool RefFinder. HPRT1 in spleen, 18 S rRNA in liver and kidney and H3F3A in heart and lymph nodes were found to be stable in the individual healthy tissue group (group A). The majority of the ASFV-infected organs (liver, kidney, heart, lymph node) exhibited H3F3A as stable reference gene with the exception of the ASFV-infected spleen, where HPRT1 was found to be the stable gene (group B). HPRT1 was found to be stable in all combinations of all CT values of both healthy and ASFV-infected porcine tissues (group C). Of five different reference genes investigated for their stability in qPCR analysis, the present study revealed that the 18 S rRNA, H3F3A and HPRT1 genes were optimal reference genes in healthy and ASFV-infected different porcine tissue samples. The study revealed the stable reference genes found in healthy as well as ASF-infected pigs and these reference genes identified through this study will form the baseline data which will be very useful in future investigations on gene expression in ASFV-infected pigs. </div> <a href="javascript:ShowArticleAbstract(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22ASFV%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">ASFV</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Data+normalization%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Data normalization</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Endogenous+control+gene%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Endogenous control gene</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+gene%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference gene</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Swine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Swine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22qRT-PCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">qRT-PCR</a></li></ul> <a href="javascript:ShowArticleKeywords(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22African+Swine+Fever%2fvirology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">African Swine Fever/virology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Swine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Swine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22African+Swine+Fever+Virus%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">African Swine Fever Virus/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Essential%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Essential/genetics</a></li></ul> <a href="javascript:ShowArticleMeSH(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Department+of+Biotechnology%2c+Ministry+of+Science+and+Technology%2c+India%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">No.BT/PR39032/ADV/90/285/2020 Department of Biotechnology, Ministry of Science and Technology, India</a></li></ul> <a href="javascript:ShowArticleGrant(22);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow23"> <td style="min-width: 40px; text-align: center;"> 23 </td> <td> <div id="citation23" class="article-citation"> <b>Shu X</b>, Hua G, Zheng X, Chen Z, Zhang J, Zhuang W, Chen J. Screening of reliable reference genes for the normalization of RT-qPCR in chicken oviduct tract. <em class='incite-journal-name' onclick='ShowInCiteJournal(19477);'>Poult Sci</em> 2024;<b>103</b>:103980. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38959666' target='_blank'>38959666</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11269787' target='_blank'>PMC11269787</a> DOI: <a href='https://dx.doi.org/10.1016/j.psj.2024.103980' target='_blank'>10.1016/j.psj.2024.103980</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.psj.2024.103980','38959666', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(23);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(23);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(23);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.psj.2024.103980' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(19477);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 05/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/05/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv23" value="10.1016/j.psj.2024.103980" /> <div style="display: none" id="articleAbstract23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Utilizing publicly available RNA-seq data to screen for ideal reference genes is more efficient and accurate than traditional methods. Previous studies have identified optimal reference genes in various chicken tissues, but none have specifically focused on the oviduct (including the infundibulum, magnum, isthmus, uterus, and vagina), which is crucial for egg production. Identifying stable reference genes in the oviduct is essential for improving research on gene expression levels. This study investigated genes with consistent expression patterns in the chicken oviduct, encompassing both individual oviduct tract tissues and the entire oviduct, by utilizing multiple RNA-seq datasets. The screening results revealed the discovery of 100 novel reference genes in each segment of oviduct tissues, primarily associated with cell cycle regulation and RNA binding. Moreover, the majority of housekeeping genes (HKGs) showed inconsistent expression levels across distinct samples, suggesting their lack of stability under varying conditions. The stability of the newly identified reference genes was assessed in comparison to previously validated stable reference genes in chicken oviduct and commonly utilized HKGs, employing traditional reference gene screening methods. HERPUD2, CSDE1, VPS35, PBRM1, LSM14A, and YWHAB were identified to be suitable novel reference gene for different parts of the oviduct. HERPUD2 and YWHAB were reliable for gene expression normalization throughout the oviduct tract. Furthermore, overexpression and interference assays in DF1 cells showed LSM14A and YWHAB play a crucial role in cell proliferation, highlighting the importance of these newly reference genes for further research. Overall, this study has expanded the options for reference genes in RT-qPCR experiments in different segments of the chicken oviduct and the entire oviduct. </div> <a href="javascript:ShowArticleAbstract(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RNA-seq%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RNA-seq</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RT-qPCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RT-qPCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22chicken%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">chicken</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22oviduct%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">oviduct</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22stable+reference+gene%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">stable reference gene</a></li></ul> <a href="javascript:ShowArticleKeywords(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chickens%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chickens/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Oviducts%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Oviducts/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fveterinary%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/veterinary</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Real-Time+Polymerase+Chain+Reaction%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Real-Time Polymerase Chain Reaction/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Genes%2c+Essential%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Genes, Essential</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Avian+Proteins%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Avian Proteins/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Avian+Proteins%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Avian Proteins/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reference+Standards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reference Standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fveterinary%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/veterinary</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Gene+Expression+Profiling%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Gene Expression Profiling/standards</a></li></ul> <a href="javascript:ShowArticleMeSH(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(23);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow24"> <td style="min-width: 40px; text-align: center;"> 24 </td> <td> <div id="citation24" class="article-citation"> <b>Nguyen Van JC</b>, Khaterchi A. [Feedback on the detection of SARS-CoV-2 by the point-of-care testing]. <em class='incite-journal-name' onclick='ShowInCiteJournal(1905);'>Ann Biol Clin (Paris)</em> 2024;<b>82</b>:281-293. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38873974' target='_blank'>38873974</a> DOI: <a href='https://dx.doi.org/10.1684/abc.2024.1891' target='_blank'>10.1684/abc.2024.1891</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1684/abc.2024.1891','38873974', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(24);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(24);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(24);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1684/abc.2024.1891' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(1905);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 06/15/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv24" value="10.1684/abc.2024.1891" /> <div style="display: none" id="articleAbstract24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">In order to improve the detection and rapid diagnosis of the SARS-CoV-2 coronavirus, we evaluated the ID NOW™ COVID-19 isothermal gene amplification technique in parallel with the real-time PCR technique (Diasorin) routinely used in the laboratory during a prospective study in the 2020 season. As this technique showed satisfactory sensitivity and specificity of 98% and 97.5% respectively, we then proposed to implement the detection of SARS-CoV-2 coronavirus in the emergency department and maternity as a point-of-care test (POCT) for the 2020-2021 season and to evaluate its clinical and organizational impact. This article summarizes the results obtained and highlights the advantages and limitations of this strategy implemented in the emergency department, particularly in terms of time spent in the department, hospitalization rates, anticoagulant treatment and early isolation of patients, as well as the organizational impact on the maternity unit. Based on this experience, we report on the regulatory constraints that apply when setting up a POCT and the steps required to validate the accreditation in accordance with standard NF EN ISO 22870. </div> <a href="javascript:ShowArticleAbstract(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22EBMD%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">EBMD</a></li><li><a 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target="_blank">molecular biology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22virology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">virology</a></li></ul> <a href="javascript:ShowArticleKeywords(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19/diagnosis</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Molecular+Diagnostic+Techniques%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Molecular Diagnostic Techniques</a></li></ul> <a href="javascript:ShowArticleMeSH(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(24);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow25"> <td style="min-width: 40px; text-align: center;"> 25 </td> <td> <div id="citation25" class="article-citation"> <b>Bustin SA</b>. RT-qPCR Testing and Performance Metrics in the COVID-19 Era. <em class='incite-journal-name' onclick='ShowInCiteJournal(11724);'>Int J Mol Sci</em> 2024;<b>25</b>:9326. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39273275' target='_blank'>39273275</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11394961' target='_blank'>PMC11394961</a> DOI: <a href='https://dx.doi.org/10.3390/ijms25179326' target='_blank'>10.3390/ijms25179326</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.3390/ijms25179326','39273275', 'Real-Time Polymerase Chain Reaction/standards')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(25);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(25);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(25);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.3390/ijms25179326' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11724);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/06/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/15/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv25" value="10.3390/ijms25179326" /> <div style="display: none" id="articleAbstract25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The COVID-19 pandemic highlighted the crucial role of diagnostic testing in managing infectious diseases, particularly through the use of reverse transcription-quantitative polymerase chain reaction (RT-qPCR) tests. RT-qPCR has been pivotal in detecting and quantifying viral RNA, enabling the identification and management of SARS-CoV-2 infections. However, despite its widespread use, there remains a notable gap in understanding fundamental diagnostic metrics such as sensitivity and specificity among many scientists and healthcare practitioners. This gap is not merely academic; it has profound implications for interpreting test results, making public health decisions, and affecting patient outcomes. This review aims to clarify the distinctions between laboratory- and field-based metrics in the context of RT-qPCR testing for SARS-CoV-2 and summarise the global efforts that led to the development and optimisation of these tests during the pandemic. It is intended to enhance the understanding of these fundamental concepts among scientists and healthcare professionals who may not be familiar with the nuances of diagnostic test evaluation. Such knowledge is crucial for accurately interpreting test results, making informed public health decisions, and ultimately managing infectious disease outbreaks more effectively. </div> <a href="javascript:ShowArticleAbstract(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RT-qPCR%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RT-qPCR</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SARS-CoV-2%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SARS-CoV-2</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22diagnostic+testing%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">diagnostic testing</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22sensitivity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">sensitivity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22specificity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">specificity</a></li></ul> <a href="javascript:ShowArticleKeywords(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%2fvirology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19/virology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SARS-CoV-2%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SARS-CoV-2/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SARS-CoV-2%2fisolation+%26amp%3b+purification%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SARS-CoV-2/isolation & purification</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RNA%2c+Viral%2fgenetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RNA, Viral/genetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RNA%2c+Viral%2fanalysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RNA, Viral/analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sensitivity+and+Specificity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sensitivity and Specificity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19+Nucleic+Acid+Testing%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19 Nucleic Acid Testing/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19+Nucleic+Acid+Testing%2fstandards%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19 Nucleic Acid Testing/standards</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19+Testing%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" 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<div class="cl"></div> </div> </div> </div> <table class="dxlpLoadingPanel_MetropolisBlue dxlpControl_MetropolisBlue" id="RootHolder_LeftLoadingPanel" style="position:absolute;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="text-align:Center;vertical-align:Top;"><span id="RootHolder_LeftLoadingPanel_TL">Loading…</span></td> </tr> </table><div id="RootHolder_LeftLoadingPanel_LD" class="dxlpLoadingDiv_MetropolisBlue dxlpControl_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1950550554" type="text/javascript">  </script> <div id="RootHolder_articleCitationPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:450px;width:600px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img 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style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1115091042" type="text/javascript">  </script> <div id="RootHolder_chartPopupControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:1000px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_chartPopupControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam"></span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_chartPopupControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_chartPopupControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_chartPopupControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_chartPopupControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_420552910" type="text/javascript">  </script> <div id="RootHolder_pcImportArticlesControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:50px;width:50px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcImportArticlesControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Import Articles</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="RootHolder_pcImportArticlesControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcImportArticlesControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcImportArticlesControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcImportArticlesControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_365297802" type="text/javascript">  </script> <div id="RootHolder_pcEditArticleControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcEditArticleControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Edit My Journal Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_pcEditArticleControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcEditArticleControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcEditArticleControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcEditArticleControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_298765222" type="text/javascript">  </script> <div id="RootHolder_userIndexComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:400px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Article Influence Index</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle2">Article Influence Index</span></b> </p> <p> Total Citations in Crossref ÷ Total Articles = <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle3">Article Influence Index</span><sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="RootHolder_userIndexComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_userIndexComputePopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_userIndexComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1286575841" type="text/javascript">  </script> <div id="RootHolder_articleExportPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:280px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow" style="font-size:11pt;"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_articleExportPopup_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Export Articles to File</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="dxtcLite_MetropolisBlue dxtcSys dxtc-init dxtc-top dxtc-pc" id="RootHolder_articleExportPopup_ExportFilePageControl" style="width:100%;"> <ul class="dxtc-strip dxtc-row dxtc-stripContainer"> <li class="dxtc-leftIndent"> </li><li class="dxtc-tab dxtc-lead" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-activeTab dxtc-lead"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-spacer"> </li><li class="dxtc-tab dxtc-last"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-activeTab dxtc-last" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-rightIndent"> </li> </ul><div class="dxtc-content"> <div> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_SearchTermText1">Real-Time Polymerase Chain Reaction/standards (366 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:5px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_1662381219" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailEndIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" value="366" type="text" /></td> </tr> </table><script id="dxss_616434442" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_1167331127" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_54524200" type="text/javascript">  </script><script id="dxss_1678130197" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" style="font-weight:bold;">JCR Year:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" type="hidden" value="2023" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" value="2023" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2023</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2022</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2021</td> </tr> </table> </div></td> </tr> </table><script id="dxss_830317689" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_167955898" type="text/javascript">  </script><script id="dxss_2013408041" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1062639383" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_104403608" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1973673553" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_6" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLTSys dxflItemSys dxflCheckBoxWithTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" style="font-weight:bold;">Record Content:</label></td> </tr><tr> <td class="dxflNestedControlCell_MetropolisBlue"> <table> <tr> <td style="vertical-align: middle; padding: 5px;"> <table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields" style="color:#BD4100;"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$cbSelectAllFields" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label>Select All Fields</label></td> </tr> </table><script id="dxss_1176833720" type="text/javascript">  </script> </td> </tr> <tr> <td style="padding: 5px;"> <table class="dxeCheckBoxList_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields" style="width:100%;border-collapse:separate;"> <tr> <td class="dxe"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields" /><table style="width:100%;"> <tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB0" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Author(s)</label></td> </tr> </table><script id="dxss_771536870" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB1" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Title</label></td> </tr> </table><script id="dxss_1086331335" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB2" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Keywords</label></td> </tr> </table><script id="dxss_1308541020" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB3" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">MESH Headings</label></td> </tr> </table><script id="dxss_896786043" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB4" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Journal Title</label></td> </tr> </table><script id="dxss_450242410" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB5" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Year</label></td> </tr> </table><script id="dxss_765036875" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB6" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Type</label></td> </tr> </table><script id="dxss_1629835480" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB7" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Language</label></td> </tr> </table><script id="dxss_1218080503" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB8" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Published Date</label></td> </tr> </table><script id="dxss_1428514578" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB9" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author</label></td> </tr> </table><script id="dxss_1113720113" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB10" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author’s Affiliations</label></td> </tr> </table><script id="dxss_310841941" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB11" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author</label></td> </tr> </table><script id="dxss_1301541094" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB12" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author’s Affiliations</label></td> </tr> </table><script id="dxss_675718561" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB13" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Email</label></td> </tr> </table><script id="dxss_2006865700" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB14" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">All Authors's Affiliations</label></td> </tr> </table><script id="dxss_1204905793" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB15" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Grant</label></td> </tr> </table><script id="dxss_407477242" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB16" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">ISSN</label></td> </tr> </table><script id="dxss_218345291" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB17" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Publisher</label></td> </tr> </table><script id="dxss_1394037744" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB18" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexing / Abstracting</label></td> </tr> </table><script id="dxss_319681069" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB19" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Factor</label></td> </tr> </table><script id="dxss_1292701966" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB20" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">JCR Quartile</label></td> </tr> </table><script id="dxss_1844280938" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB21" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Index Per Article</label></td> </tr> </table><script id="dxss_838303323" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB22" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Category</label></td> </tr> </table><script id="dxss_1464125856" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB23" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Times Cited in RCA</label></td> </tr> </table><script id="dxss_148257179" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB24" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Peer-Reviewed Journal</label></td> </tr> </table><script id="dxss_950217086" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB25" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Open Access</label></td> </tr> </table><script id="dxss_1732367175" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB26" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">DOI</label></td> </tr> </table><script id="dxss_1936777588" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB27" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">PMID</label></td> </tr> </table><script id="dxss_745806673" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB28" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Citation</label></td> </tr> </table><script id="dxss_1835441810" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB29" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexed in RCA</label></td> </tr> </table><script id="dxss_847142451" type="text/javascript">  </script></td><td></td><td></td> </tr> </table></td> </tr> </table><script id="dxss_1169734383" type="text/javascript">  </script> </td> </tr> </table> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_7" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportedDetailFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_1198171345" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_1960175520" type="text/javascript">  </script> </div> </div><div style="display:none;"> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_SearchTermText2">Real-Time Polymerase Chain Reaction/standards (366 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:10px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_814491935" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportEndSIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" value="366" type="text" /></td> </tr> </table><script id="dxss_1331245653" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:10px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_2046065225" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_1926633208" type="text/javascript">  </script><script id="dxss_228619664" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:20px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" type="hidden" value="1" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" value="Excel" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1509722775" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_960798088" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_835950349" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportedFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_308093146" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_424125632" type="text/javascript">  </script> </div> </div> </div> </div><b class="dx-clear"></b><table id="RootHolder_articleExportPopup_ExportFilePageControl_LP" class="dxtcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_TL">Loading…</span></td> </tr> </table><script id="dxss_2124675053" type="text/javascript">  </script> </div> </div><div class="dxpc-footer"> <div class="popup-footer-button-container"> <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles_I" class="dxb-hb" value="Export" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnExportArticles" /><span class="dx-vam">Export</span> </div> </div><script id="dxss_77486387" type="text/javascript">  </script>    <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnCancel" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnCancel_I" class="dxb-hb" value="Cancel" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnCancel" /><span class="dx-vam">Cancel</span> </div> </div><script id="dxss_2118985763" type="text/javascript">  </script> </div> </div> </div> </div><div id="RootHolder_articleExportPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_articleExportPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="font-size:11pt;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="font-size:11pt;padding-left:0px;"><span id="RootHolder_articleExportPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_578446409" type="text/javascript">  </script> </div> <div class="bottom-part cl"> © 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA </div> <div class="scroll"> <a href="#top" target="_self"> <img src="/Contents/Images/backtop3.png" /> </a> </div> <div id="categorySelectorPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Select the Category</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="categorySelectorPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="categorySelectorPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="categorySelectorPopup_TL">Loading…</span></td> </tr> </table><div id="categorySelectorPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_166253781" type="text/javascript">  </script> <div id="pcLoginPopUp_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:700px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="pcLoginPopUp_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="pcLoginPopUp_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="pcLoginPopUp_TL">Loading…</span></td> </tr> </table><div id="pcLoginPopUp_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_430910140" type="text/javascript">  </script> <div id="aiComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:300px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Impact Index Per Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for Impact Index Per Article</b> </p> <p> Times Cited ÷ Number of Years = Impact Index Per Article<sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="aiComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="aiComputePopup_TL">Loading…</span></td> </tr> </table><div id="aiComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_698179129" type="text/javascript">  </script> <script type="text/javascript"> //<![CDATA[ var callBackFrameUrl='/WebResource.axd?d=beToSAE3vdsL1QUQUxjWdX-3aFLejnBliGvqSCZYULGFdxZmRlcJcqs71AKVNTQEXljNmd0slFkUZ_AFaCke4Q2&t=638628207619783110'; WebForm_InitCallback();//]]> </script> </form> </body> </html>