Schweizerische 3R-Kompetenzzentrum

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fill="#222240"/> <path id="Pfad_27" data-name="Pfad 27" d="M160.123,77.735a3.338,3.338,0,0,0,1.324-1.515.3.3,0,0,1,.4-.157l.009,0,.458.178c.2.086.263.221.178.408a4.522,4.522,0,0,1-1.757,2.063,5.194,5.194,0,0,1-2.852.764,4.966,4.966,0,0,1-2.967-.866,4.533,4.533,0,0,1-1.694-2.369,12.407,12.407,0,0,1-.356-3.412q0-1.248.038-1.885a6.81,6.81,0,0,1,.165-1.171,4.559,4.559,0,0,1,1.669-2.573,4.925,4.925,0,0,1,3.094-.967,4.561,4.561,0,0,1,4.864,4,8.356,8.356,0,0,1,.14,1.057q.039.547.038,1.668,0,.332-.305.331h-8.277a.09.09,0,0,0-.1.076.114.114,0,0,0,0,.026,12.252,12.252,0,0,0,.127,2.19,3.382,3.382,0,0,0,1.248,1.974,3.836,3.836,0,0,0,2.42.751,4.176,4.176,0,0,0,2.139-.573m-5.934-5.641a.09.09,0,0,0,.076.1H161.4a.09.09,0,0,0,.1-.076.057.057,0,0,0,0-.026,10.71,10.71,0,0,0-.127-1.935,3.432,3.432,0,0,0-1.222-1.974,3.967,3.967,0,0,0-4.61-.026,3.228,3.228,0,0,0-1.172,1.923,11.309,11.309,0,0,0-.178,2.012" fill="#222240"/> </g> </g> </svg> </a> <div class="megamenu blue"> <button class="dropbtn"><svg 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stroke-width="1"/> </svg> </button> </div> </div> </nav> <div class="no-banner"></div> <div class="blocks pb-200"> <div id="0e962a58-55c9-4d25-bf4b-f963002da138" class="block block-type-title_modul"> <section class="title mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <h1 style="color:#222240"> 3Rs resources </h1> </div> </div> </div> </section></div> <div id="95d3d29d-1c09-4992-b453-464b1e223b7d" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <img src="https://swiss3rcc.org/media/pages/3rs-resources/cd8009ec5c-1642821368/2021-3rcc-214-500x-crop.jpg" class=" img-fluid col-md-3 img_right" alt=""> <h2>New mouse-handling methods</h2> <p>Laboratory mice are routinely handled for husbandry and scientific procedures. Traditionally mice are initially picked up by the base of the tail, sometimes with a hand positioned to support the animal’s body. <strong>Picking up mice by the tail can compromise their welfare and affect scientific outcomes. </strong><a href="https://www.nc3rs.org.uk/news/recommended-techniques-handling-lab-mice-reduce-anxiety" target="_blank" rel="noopener noreferrer">Research </a>has shown that picking up mice by the tail induces aversion and high anxiety levels, as assessed by a range of measures, which can be minimised by instead using a tunnel or a cupped hand. As well as having animal welfare benefits the research, led by Jane Hurst at the University of Liverpool, has shown that picking up mice by the tail can impact on scientific outcomes, with mice handled by tunnel and cupping methods showing improved performance in <a href="https://nc3rs.org.uk/news/results-mouse-studies-deeply-affected-way-animals-are-handled" target="_blank" rel="noopener noreferrer">behavioural tests</a> compared to traditional tail handling. The research has since been replicated by other groups, who have shown that the method of handling can affect <a href="https://www.sciencedirect.com/science/article/abs/pii/S0031938415003571" target="_blank" rel="noopener noreferrer">physiological parameters</a> and behaviour, including the response to <a href="http://www.nature.com/articles/s41598-018-20716-3" target="_blank" rel="noopener noreferrer">reward</a>. The 3RCC contributed to the German translation of the poster. <strong>You may order posters in German and French by sending a message to chantal.britt[at]swiss3rcc.org.</strong></p><p>Find more information about mouse handling and watch tutorials on <a href="https://www.nc3rs.org.uk/how-to-pick-up-a-mouse" target="_blank" rel="noopener noreferrer">NC3Rs website</a>.</p><p>During the COVID-19 pandemic, the NC3Rs <a href="https://nc3rs.org.uk/news/nc3rs-and-3rs-during-covid-19" target="_blank" rel="noopener noreferrer">offers </a>different <a href="https://www.nc3rs.org.uk/e-learning-resources" target="_blank" rel="noopener noreferrer">e-learning resources</a>, <a href="https://www.nc3rs.org.uk/experimental-design" target="_blank" rel="noopener noreferrer">experimental desing resources</a> and for example information on <a href="https://www.nc3rs.org.uk/3rs-resources/housing-and-husbandry" target="_blank" rel="noopener noreferrer">housing and husbandry</a>. </p> </div> </div> </div> </div> </section></div> <div id="c5a98d36-978a-4d0e-a56d-c24eace8fc85" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <img src="https://swiss3rcc.org/media/pages/3rs-resources/873537e93d-1642821724/2021-3rcc-240-500x-crop.jpg" class=" img-fluid col-md-3 img_left" alt=""> <h2>How to tickle a rat: get your certificate!</h2> <p>At the Gaskill lab at Purdue University, scientists conduct research to better understand the best methods to improve rat welfare. One of their areas of focus is <strong>rat tickling. </strong>Rat tickling is a technique that was developed to study play and positive affect in laboratory rats. It mimics rat rough-and-tumble play using a human hand. Typically it involves using your hand to “wrestle” with a rat in a playful manner. Tickling improves handling, minimizes fear, and can act as social enrichment. Tickling is also fun for the handlers and can increase personnel satisfaction! increase their positive approach behavior, reduce rat fear, minimize negative effects from negative procedures such as transport or injection, may decrease handling time, increase personnel satisfaction, and act as social enrichment for isolated rats. Rats prefer to be tickled than stroked by their human handlers.</p><p>Check out the tutorial and training videos on <a href="https://ag.purdue.edu/ansc/gaskill/resources/" target="_blank" rel="noopener noreferrer">website</a> of Purdue University and take the rat tickling certificate course <a href="http://bit.ly/RatTicklingCertificate?_ga=2.154312952.1947785687.1585307088-115653022.1585307088" target="_blank" rel="noopener noreferrer">available</a>.</p><p>Quick <a href="https://ag.purdue.edu/ansc/gaskill/wp-content/uploads/2018/08/How-to-Tickle-a-Rat-Handout_2018_engl_fra_deut.pdf" target="_blank" rel="noopener noreferrer">slide presentation</a> in English, German, French, credit Megan LaFollette, Purdue University</p> </div> </div> </div> </div> </section></div> <div id="a513452f-39a7-4551-8827-9a06c0445cc7" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <h2>UZH SampleSizeR tool helps researchers calculate samples sizes</h2> <p>The statistics group at the University of Zurich led by Bernadetta Tarigan built a tool that allows researchers to calculate the optimal sample sizes within completely randomized design (CRD). The tool was developed specifically with to help investigators design better animal studies.<br><br><a href="http://shiny.math.uzh.ch/git/reinhard.furrer/SampleSizeR/" target="_blank" rel="noopener noreferrer">SampleSizeR</a> Tool of UZH</p> </div> </div> </div> </div> </section></div> <div id="008619eb-0d6e-411f-a6af-bb6d89c1bf0d" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <h2>3R Smart provides training material in German</h2> <p>The 3R Smart is an information and training platform, which addresses interested laymen as well as scientists and technical staff. The project is funded by the German Ministry of Education and Research (BMBF) and coordinated and developed by the University of Veterinary Medicine Hannover Foundation and the Philipps University Marburg.</p> </div> </div> </div> </div> </section></div> <div id="ffcf633d-3c17-4623-8e69-62132a5ae8ce" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <h2>Radboud's Syrcle offers online modules on how to conduct systematic reviews</h2> <p>The SYstematic Review Center for Laboratory animal Experimentation (SYRCLE) envisions a world in which any animal-based research conducted is justified, rigorous and of high translational value. Our mission is to develop, apply and disseminate the methodology of systematic reviews of animal studies to advance responsible animal-based research.</p> </div> </div> </div> </div> </section></div> <div id="ff9ec8e7-9fb0-45cd-a5f1-8dd3f5595b37" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <h2>Norecopa resources for home learning</h2> <p>Norway's National Consensus Platform for the advancement of the 3Rs suggests resources which may be suitable for schoolchildren and undergraduate students undertaking home learning in connection with the Covid-19 pandemic. Emphasis has been placed on products which are available online, thereby avoiding the need for purchase of equipment.</p> </div> </div> </div> </div> </section></div> <div id="54343d17-6d31-4c1f-af68-1f15b8487066" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <h2>Research Animal Training offer e-learning modules</h2> <p>A collection of educational resources to support you when studying for a Home Office Licensee PIL AB or PIL C course. Resources are also provided to support some of the training needs of those applying for a Project Licence.</p><p>The articles and eLearning modules on this site align with the learning outcomes specified for each <a href="https://researchanimaltraining.com/training-courses/licence-requirements/" target="_blank" rel="noopener noreferrer">EU training module</a>. Some learning outcomes require practical tuition and this should be provided in person to you. Further information for <a href="https://researchanimaltraining.com/training-courses" target="_blank" rel="noopener noreferrer">course attendees</a>, a listing of the <a href="https://researchanimaltraining.com/elearning-modules/" target="_blank" rel="noopener noreferrer">eLearning modules</a> currently available, a website <a href="https://researchanimaltraining.com/features/" target="_blank" rel="noopener noreferrer">feature list</a>, <a href="https://researchanimaltraining.com/features/" target="_blank" rel="noopener noreferrer">FAQ page</a> and some <a href="https://researchanimaltraining.com/features/" target="_blank" rel="noopener noreferrer">example screens</a> .</p> </div> </div> </div> </div> </section></div> <div id="ef8a7e24-ddb9-427c-81a5-d565bf524611" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <h2>Berlin Institute of Health's educational resources</h2> <p>Around the world, many researchers have found themselves in self-isolation, and are unable to continue performing lab-based studies. However, this can be an opportunity to learn and expand professional and scientific horizons. We have created a list of resources to help you make the best of this strange and challenging time, and increase the quality of your research in the future.</p> </div> </div> </div> </div> </section></div> <div id="b9af87a9-f354-461d-b297-d5479671cce6" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <h2>Resources of the Swiss Institute of Bioinformatics</h2> <p>SIB experts and resources are taking part in the global effort to develop dedicated data services, analysis tools and improve knowledge sharing to fight the COVID-19 pandemic.</p><p>Find a list of tools on a dedicated <a href="https://www.sib.swiss/about-sib/news/10660-sib-resources-supporting-sars-cov-2-research?utm_source=newsletter&utm_medium=email&utm_campaign=swiss-bioinformatics-08_04_2020&utm_content=covid-resources-list" target="_blank" rel="noopener noreferrer">website</a> of the SIB.</p> </div> </div> </div> </div> </section></div> <div id="b9606f33-1e3d-4d67-bc13-049898be5cf3" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <h2>American Society for Cellular and Computational Toxicology webinars</h2> <p>American Society for Cellular and Computational Toxicology holds <a href="https://www.ascctox.org/webinars" target="_blank" rel="noopener noreferrer">webinars</a> on new animal-free testing methodologies. The webinars are available for all to attend and watch at no cost. However, after the event the videos are only available to ASCCT members.</p> </div> </div> </div> </div> </section></div> <div id="705d54d6-855c-4a5a-a959-2c71f7701edd" class="block block-type-textimage_modul"> <section class="textimage mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <div class="clearfix"> <h2>Johns Hopkins CAAT offers range of non-animal resources</h2> <p>Johns Hopkins University's Center for Alternatives to Animal Testing (<a href="https://caat.jhsph.edu/" target="_blank" rel="noopener noreferrer">CAAT</a>) offers a range of programs that seek to provide a better, safer, more humane future for people and animals.</p> </div> </div> </div> </div> </section></div> <div id="0c50272f-5b13-4303-bf4c-5410631efaeb" class="block block-type-text_modul"> <section class="text mt_80_normal"> <div class="container"> <div class="row"> <div class="col"> <h2>Online-Portal informiert über Fortschritte in der 3R-Forschung</h2> <p>Die Forschungsverbünde „Severity Assessment in Animal Based Research“ und „R2N-Replace und Reduce aus Niedersachsen“ bzw. „Micro-Replace-Systeme“ geben auf der Webseite <u><a href="https://www.3r-forschung.de/" title="https://www.3r-forschung.de/" rel="noopener noreferrer">www.3R-Forschung.de</a></u> umfänglich Einblicke in Inhalte und Entwicklungen der 3R-Forschung. Die Online-Plattform bietet Interessierten die Möglichkeit, sich über den Stand und die Fortschritte der 3R-Forschung zur Vermeidung, Verringerung und Verfeinerung (Replace, Reduce, Refine) von Tierversuchen zu informieren. </p><p>Das Portal soll das Bewusstsein und Verständnis für das 3R-Prinzip fördern und den Austausch von Informationen und bewährten Verfahren zwischen Forschungseinrichtungen und anderen Organisationen erleichtern. Nutzende finden auf der Website <u><a href="https://www.3r-forschung.de/" title="https://www.3r-forschung.de/" rel="noopener noreferrer">www.3R-Forschung.de</a></u> Factsheets, Grafiken und Texte, die einen niedrigschwelligen Einstieg in Themen rund um das 3R-Prinzip bieten. Interessierte können sich durch <u><a href="https://www.3r-forschung.de/interview-mit-prof-dr-andre-bleich/" title="https://www.3r-forschung.de/interview-mit-prof-dr-andre-bleich/" rel="noopener noreferrer">Interview</a></u>s über Ziele und Erfolge in der 3R-Forschung informieren sowie durch Factsheets im <u><a href="https://www.3r-forschung.de/_3r-downloads/" title="https://www.3r-forschung.de/_3r-downloads/" rel="noopener noreferrer">Download-Bereich</a></u> informative Grafiken herunterladen. Das <u><a href="https://3r-forschung.de/wp-content/uploads/2022/07/3r_portal_factsheet_alternativmethoden.pdf" title="https://3r-forschung.de/wp-content/uploads/2022/07/3r_portal_factsheet_alternativmethoden.pdf" rel="noopener noreferrer">Factsheet „Alternativmethoden“</a></u> etwa liefert interessantes Wissen, wie Forschende Tierversuche im Sinne des „Replace“ durch tierversuchsfreie Technologien und Modelle ersetzen können. </p><p> </p> </div> </div> </div> </section></div> </div> <footer class="footer"> <div class="container"> <div class="row"> <div class="col-12 col-lg-4 footer-logo"> <a class="navbrand" href="https://swiss3rcc.org/de"> <svg xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="227.428" height="80.009" viewBox="0 0 227.428 80.009"> <defs> <clipPath id="clip-path"> <rect id="Rechteck_2" data-name="Rechteck 2" width="227.428" height="80.009" transform="translate(0 0)" fill="none"/> </clipPath> </defs> <g id="Logo" transform="translate(0 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