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<!doctype html> <html lang="ru"> <head> <title>Вирусные векторы и генная терапи | 63698</title> <meta name="keywords" content="Самира Мирбаха , "/> <meta name="description" content="The discovery of DNA as the biomolecule of genetic inheritance and disease opened the prospect of therapies in which mutant and damaged genes could be alte..63698"/> <meta name="citation_publisher" content="Лонгдом издательская СЛ" /> <meta name="citation_journal_title" content="Достижения в области генной инженерии"> <meta name="citation_title" content="Вирусные векторы и генная терапия "> <meta name="citation_author" content="Самира Мирбаха" /> <meta name="citation_year" content=""> <meta name="citation_volume" content="10"> <meta name="citation_issue" content="1"> <meta name="citation_abstract" content="The discovery of DNA as the biomolecule of genetic inheritance and disease opened the prospect of therapies in which mutant and damaged genes could be altered for the improvement of the human condition. Genome-editing is a technology that allows specific changes in the genes of interest. This approach is capable of manipulating the genome of living cells or organisms in various ways: insertions or deletions of chosen genes, introduction of point mutations, knockout or correction of specific genes3 Gene therapy provides a unique approach to treat a variety of both inherited and acquired diseases2 by delivering a therapeutic gene material to correct the loss�?�of�?�function caused by mutation or to express the deficient gene product. Despite years of preclinical studies, it was not until the early 1990s that the first gene therapies were studied in humans In fact, the first clinical trial to gain approval for transfer of a foreign gene into humans was conducted at the National Cancer Institute in Bethesda in 1990.6 In spite of numerous setbacks, efficacious gene-based therapies still hold the great promise to revolutionize the clinical management of human diseases. 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class="heading-1">Абстрактный</h2> <h3 class="">Вирусные векторы и генная терапия </h3> <p> <i class="fas fa-user"></i> Самира Мирбаха </p> <p>The discovery of DNA as the biomolecule of genetic inheritance and disease opened the prospect of therapies in which mutant and damaged genes could be altered for the improvement of the human condition. Genome-editing is a technology that allows specific changes in the genes of interest. This approach is capable of manipulating the genome of living cells or organisms in various ways: insertions or deletions of chosen genes, introduction of point mutations, knockout or correction of specific genes3 Gene therapy provides a unique approach to treat a variety of both inherited and acquired diseases2 by delivering a therapeutic gene material to correct the loss�?�of�?�function caused by mutation or to express the deficient gene product. Despite years of preclinical studies, it was not until the early 1990s that the first gene therapies were studied in humans In fact, the first clinical trial to gain approval for transfer of a foreign gene into humans was conducted at the National Cancer Institute in Bethesda in 1990.6 In spite of numerous setbacks, efficacious gene-based therapies still hold the great promise to revolutionize the clinical management of human diseases.</p> <div class="alert alert-info text-left"><b>Отказ от ответственности:</b> Этот тезис был переведен с использованием инструментов искусственного интеллекта и еще не прошел рецензирование или проверку.</div> <div class="nav social-icons"> <a class="nav-link w-auto">Поделитесь этой статьей</a> <a title="Нажмите здесь" target="_blank" href="https://www.facebook.com/sharer.php?u=https://russian.longdom.org/abstract/viral-vectors-and-the-gene-therapy-63698.html" rel="noopener"><i class="fab fa-facebook-f"></i></a> <a class="nav-link" title="Нажмите здесь" target="_blank" href="https://twitter.com/share?url=https://russian.longdom.org/abstract/viral-vectors-and-the-gene-therapy-63698.html" rel="noopener"><i class="fab fa-twitter"></i></a> <a class="nav-link" title="Нажмите здесь" target="_blank" href="https://www.linkedin.com/shareArticle?mini=true&url=https://russian.longdom.org/abstract/viral-vectors-and-the-gene-therapy-63698.html" rel="noopener"><i class="fab fa-linkedin-in"></i></a> <a class="nav-link" title="Нажмите здесь" target="_blank" href="https://plus.google.com/share?url=https://russian.longdom.org/abstract/viral-vectors-and-the-gene-therapy-63698.html" rel="noopener"><i class="fab fa-google-plus-g"></i></a> </div> </div> </div> </div> </section> <footer class="bg-blue-grey-900 py-3"> <div class="container"> <div class="row"> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">Ссылки на контент</h4> <ul class="list-unstyled footer-links font-size-3"> <li><a class="" href="https://russian.longdom.org/privacy-policy.html" title="Нажмите здесь">Политика конфиденциальности</a></li> <li><a class="" href="https://russian.longdom.org/terms-conditions.html" title="Нажмите здесь">Условия использования</a></li> <li><a class="" href="https://russian.longdom.org/authors-reviewers-editors.html" title="Нажмите здесь">Авторы, рецензенты и редакторы</a></li> </ul> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">Связаться с Лонгдом</h4> <p><strong>Longdom Group SA</strong><br /> Авеню Роджера Вандендрише,<br /> 18, 1150 Брюссель, Бельгия<br /> Телефон: +442038085340<br /> <strong>Электронная почта:</strong> <a class="white" href="mailto:info@longdom.org" title="Нажмите здесь">info@longdom.org</a></p> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">Соединять</h4> <nav class="nav nav-pills social-icons-footer flex-column a-pl-0"> <a href="https://www.facebook.com/longdompublisher" title="Нажмите здесь" target="_blank" class="nav-link bg-facebook-hover"><i class="fab fa-facebook-f bg-facebook"></i></a> <a href="https://www.linkedin.com/company/longdom-publishing-sl/" title="Нажмите здесь" target="_blank" class="nav-link bg-linkedin-hover"><i class="fab fa-linkedin-in bg-linkedin"></i></a> <a href="https://twitter.com/LongdomP" title="Нажмите здесь" target="_blank" class="nav-link bg-twitter-hover"><i class="fab fa-twitter bg-twitter"></i></a> <a href="https://www.instagram.com/longdom_publisher/" title="Нажмите здесь" target="_blank" class="nav-link bg-instagram-hover"><i class="fab fa-instagram bg-instagram"></i></a> </nav> </div> </div> <div class="row text-center"> <div class="col"> <p>Авторские права © 2025 <a href="https://russian.longdom.org/" title="Нажмите здесь" class="white">Издательство Longdom SL</a>.</p> </div> </div> </div> </footer>  <a href="#0" class="cd-top js-cd-top">Top</a>   <script src="https://code.jquery.com/jquery-3.3.1.min.js"></script> <script src="https://cdnjs.cloudflare.com/ajax/libs/popper.js/1.14.7/umd/popper.min.js"></script> <script src="https://stackpath.bootstrapcdn.com/bootstrap/4.3.1/js/bootstrap.min.js"></script>  <script> jQuery(function($) { $(window).scroll(function fix_element() { $('#target').css( $(window).scrollTop() > 100 ? 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