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Chimie farmaceutică - Wikipedia

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Disponibil în 46 limbi" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-46" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">46 limbi</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%83%D9%8A%D9%85%D9%8A%D8%A7%D8%A1_%D8%AF%D9%88%D8%A7%D8%A6%D9%8A%D8%A9" title="كيمياء دوائية – arabă" lang="ar" hreflang="ar" data-title="كيمياء دوائية" data-language-autonym="العربية" data-language-local-name="arabă" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-ast mw-list-item"><a href="https://ast.wikipedia.org/wiki/Qu%C3%ADmica_melecinal" title="Química melecinal – asturiană" lang="ast" hreflang="ast" data-title="Química melecinal" data-language-autonym="Asturianu" data-language-local-name="asturiană" class="interlanguage-link-target"><span>Asturianu</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%9C%D0%B5%D0%B4%D0%B8%D1%86%D0%B8%D0%BD%D1%81%D0%BA%D0%B0_%D1%85%D0%B8%D0%BC%D0%B8%D1%8F" title="Медицинска химия – bulgară" lang="bg" hreflang="bg" data-title="Медицинска химия" data-language-autonym="Български" data-language-local-name="bulgară" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bn mw-list-item"><a href="https://bn.wikipedia.org/wiki/%E0%A6%94%E0%A6%B7%E0%A6%A7%E0%A7%80%E0%A6%AF%E0%A6%BC_%E0%A6%B0%E0%A6%B8%E0%A6%BE%E0%A6%AF%E0%A6%BC%E0%A6%A8" title="ঔষধীয় রসায়ন – bengaleză" lang="bn" hreflang="bn" data-title="ঔষধীয় রসায়ন" data-language-autonym="বাংলা" data-language-local-name="bengaleză" class="interlanguage-link-target"><span>বাংলা</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Medicinska_hemija" title="Medicinska hemija – bosniacă" lang="bs" hreflang="bs" data-title="Medicinska hemija" data-language-autonym="Bosanski" data-language-local-name="bosniacă" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Qu%C3%ADmica_farmac%C3%A8utica" title="Química farmacèutica – catalană" lang="ca" hreflang="ca" data-title="Química farmacèutica" data-language-autonym="Català" data-language-local-name="catalană" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-ckb mw-list-item"><a href="https://ckb.wikipedia.org/wiki/%DA%A9%DB%8C%D9%85%DB%8C%D8%A7%DB%8C_%D8%AF%DB%95%D8%B1%D9%85%D8%A7%D9%86%DB%8C" title="کیمیای دەرمانی – kurdă centrală" lang="ckb" hreflang="ckb" data-title="کیمیای دەرمانی" data-language-autonym="کوردی" data-language-local-name="kurdă centrală" class="interlanguage-link-target"><span>کوردی</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Medicinalkemi" title="Medicinalkemi – daneză" lang="da" hreflang="da" data-title="Medicinalkemi" data-language-autonym="Dansk" data-language-local-name="daneză" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Medizinische_Chemie" title="Medizinische Chemie – germană" lang="de" hreflang="de" data-title="Medizinische Chemie" data-language-autonym="Deutsch" data-language-local-name="germană" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Medicinal_chemistry" title="Medicinal chemistry – engleză" lang="en" hreflang="en" data-title="Medicinal chemistry" data-language-autonym="English" data-language-local-name="engleză" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Qu%C3%ADmica_medicinal" title="Química medicinal – spaniolă" lang="es" hreflang="es" data-title="Química medicinal" data-language-autonym="Español" data-language-local-name="spaniolă" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Kimika_sendagarri" title="Kimika sendagarri – bască" lang="eu" hreflang="eu" data-title="Kimika sendagarri" data-language-autonym="Euskara" data-language-local-name="bască" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%B4%DB%8C%D9%85%DB%8C_%D8%AF%D8%A7%D8%B1%D9%88%DB%8C%DB%8C" title="شیمی دارویی – persană" lang="fa" hreflang="fa" data-title="شیمی دارویی" data-language-autonym="فارسی" data-language-local-name="persană" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/L%C3%A4%C3%A4keainekemia" title="Lääkeainekemia – finlandeză" lang="fi" hreflang="fi" data-title="Lääkeainekemia" data-language-autonym="Suomi" data-language-local-name="finlandeză" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Chimie_pharmaceutique" title="Chimie pharmaceutique – franceză" lang="fr" hreflang="fr" data-title="Chimie pharmaceutique" data-language-autonym="Français" data-language-local-name="franceză" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%9B%D7%99%D7%9E%D7%99%D7%94_%D7%AA%D7%A8%D7%95%D7%A4%D7%AA%D7%99%D7%AA" title="כימיה תרופתית – ebraică" lang="he" hreflang="he" data-title="כימיה תרופתית" data-language-autonym="עברית" data-language-local-name="ebraică" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%94%E0%A4%B7%E0%A4%A7%E0%A5%80%E0%A4%AF_%E0%A4%B0%E0%A4%B8%E0%A4%BE%E0%A4%AF%E0%A4%A8" title="औषधीय रसायन – hindi" lang="hi" hreflang="hi" data-title="औषधीय रसायन" data-language-autonym="हिन्दी" data-language-local-name="hindi" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Medicinska_kemija" title="Medicinska kemija – croată" lang="hr" hreflang="hr" data-title="Medicinska kemija" data-language-autonym="Hrvatski" data-language-local-name="croată" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Gy%C3%B3gyszerk%C3%A9mia" title="Gyógyszerkémia – maghiară" lang="hu" hreflang="hu" data-title="Gyógyszerkémia" data-language-autonym="Magyar" data-language-local-name="maghiară" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D4%B4%D5%A5%D5%B2%D5%B8%D6%80%D5%A1%D5%B5%D6%84%D5%A1%D5%B5%D5%AB%D5%B6_(%D5%A4%D5%A5%D5%B2%D5%A1%D5%A3%D5%B8%D6%80%D5%AE%D5%A1%D5%AF%D5%A1%D5%B6)_%D6%84%D5%AB%D5%B4%D5%AB%D5%A1" title="Դեղորայքային (դեղագործական) քիմիա – armeană" lang="hy" hreflang="hy" data-title="Դեղորայքային (դեղագործական) քիմիա" data-language-autonym="Հայերեն" data-language-local-name="armeană" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Kimia_medisinal" title="Kimia medisinal – indoneziană" lang="id" hreflang="id" data-title="Kimia medisinal" data-language-autonym="Bahasa Indonesia" data-language-local-name="indoneziană" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E5%8C%BB%E8%96%AC%E5%93%81%E5%8C%96%E5%AD%A6" title="医薬品化学 – japoneză" lang="ja" hreflang="ja" data-title="医薬品化学" data-language-autonym="日本語" data-language-local-name="japoneză" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-jv mw-list-item"><a href="https://jv.wikipedia.org/wiki/Kimia_medis" title="Kimia medis – javaneză" lang="jv" hreflang="jv" data-title="Kimia medis" data-language-autonym="Jawa" data-language-local-name="javaneză" class="interlanguage-link-target"><span>Jawa</span></a></li><li class="interlanguage-link interwiki-kn mw-list-item"><a href="https://kn.wikipedia.org/wiki/%E0%B2%94%E0%B2%B7%E0%B2%A7%E0%B3%80%E0%B2%AF_%E0%B2%B0%E0%B2%B8%E0%B2%BE%E0%B2%AF%E0%B2%A8%E0%B2%B6%E0%B2%BE%E0%B2%B8%E0%B3%8D%E0%B2%A4%E0%B3%8D%E0%B2%B0" title="ಔಷಧೀಯ ರಸಾಯನಶಾಸ್ತ್ರ – kannada" lang="kn" hreflang="kn" data-title="ಔಷಧೀಯ ರಸಾಯನಶಾಸ್ತ್ರ" data-language-autonym="ಕನ್ನಡ" data-language-local-name="kannada" class="interlanguage-link-target"><span>ಕನ್ನಡ</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%9D%98%EC%95%BD%ED%99%94%ED%95%99" title="의약화학 – coreeană" lang="ko" hreflang="ko" data-title="의약화학" data-language-autonym="한국어" data-language-local-name="coreeană" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%A4%D0%B0%D1%80%D0%BC%D0%B0%D1%86%D0%B5%D0%B2%D1%82%D1%81%D0%BA%D0%B0_%D1%85%D0%B5%D0%BC%D0%B8%D1%98%D0%B0" title="Фармацевтска хемија – macedoneană" lang="mk" hreflang="mk" data-title="Фармацевтска хемија" data-language-autonym="Македонски" data-language-local-name="macedoneană" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Kimia_perubatan" title="Kimia perubatan – malaeză" lang="ms" hreflang="ms" data-title="Kimia perubatan" data-language-autonym="Bahasa Melayu" data-language-local-name="malaeză" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Medicinale_chemie" title="Medicinale chemie – neerlandeză" lang="nl" hreflang="nl" data-title="Medicinale chemie" data-language-autonym="Nederlands" data-language-local-name="neerlandeză" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/Legemiddelkjemi" title="Legemiddelkjemi – norvegiană bokmål" lang="nb" hreflang="nb" data-title="Legemiddelkjemi" data-language-autonym="Norsk bokmål" data-language-local-name="norvegiană bokmål" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Chemia_lek%C3%B3w" title="Chemia leków – poloneză" lang="pl" hreflang="pl" data-title="Chemia leków" data-language-autonym="Polski" data-language-local-name="poloneză" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Qu%C3%ADmica_medicinal" title="Química medicinal – portugheză" lang="pt" hreflang="pt" data-title="Química medicinal" data-language-autonym="Português" data-language-local-name="portugheză" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9C%D0%B5%D0%B4%D0%B8%D1%86%D0%B8%D0%BD%D1%81%D0%BA%D0%B0%D1%8F_%D1%85%D0%B8%D0%BC%D0%B8%D1%8F" title="Медицинская химия – rusă" lang="ru" hreflang="ru" data-title="Медицинская химия" data-language-autonym="Русский" data-language-local-name="rusă" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Medicinska_hemija" title="Medicinska hemija – sârbo-croată" lang="sh" hreflang="sh" data-title="Medicinska hemija" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="sârbo-croată" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Pharmaceutical_chemistry" title="Pharmaceutical chemistry – Simple English" lang="en-simple" hreflang="en-simple" data-title="Pharmaceutical chemistry" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Medic%C3%ADnska_ch%C3%A9mia" title="Medicínska chémia – slovacă" lang="sk" hreflang="sk" data-title="Medicínska chémia" data-language-autonym="Slovenčina" data-language-local-name="slovacă" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sq mw-list-item"><a href="https://sq.wikipedia.org/wiki/Kimia_farmaceutike" title="Kimia farmaceutike – albaneză" lang="sq" hreflang="sq" data-title="Kimia farmaceutike" data-language-autonym="Shqip" data-language-local-name="albaneză" class="interlanguage-link-target"><span>Shqip</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Medicinska_hemija" title="Medicinska hemija – sârbă" lang="sr" hreflang="sr" data-title="Medicinska hemija" data-language-autonym="Српски / srpski" data-language-local-name="sârbă" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/L%C3%A4kemedelskemi" title="Läkemedelskemi – suedeză" lang="sv" hreflang="sv" data-title="Läkemedelskemi" data-language-autonym="Svenska" data-language-local-name="suedeză" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-ta mw-list-item"><a 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data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">De la Wikipedia, enciclopedia liberă</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="ro" dir="ltr"><figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/Fi%C8%99ier:Bzr_pm.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6f/Bzr_pm.png/220px-Bzr_pm.png" decoding="async" width="220" height="165" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/6f/Bzr_pm.png/330px-Bzr_pm.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/6f/Bzr_pm.png/440px-Bzr_pm.png 2x" data-file-width="1440" data-file-height="1080" /></a><figcaption>Model <a href="/wiki/Farmacofor" title="Farmacofor">farmacofor</a> al situsului de legare pentru <a href="/wiki/Benzodiazepine" class="mw-redirect" title="Benzodiazepine">benzodiazepine</a> pe receptorul GABAA.</figcaption></figure> <p><b>Chimia medicală</b> și <b>chimia farmaceutică</b> sunt discipline științifice care se află la intersecția dintre <a href="/wiki/Chimie" title="Chimie">chimie</a> (în special <a href="/wiki/Chimie_organic%C4%83" title="Chimie organică">chimia organică</a> de <a href="/wiki/Sintez%C4%83_organic%C4%83" title="Sinteză organică">sinteză</a>) și <a href="/wiki/Farmacologie" title="Farmacologie">farmacologie</a> și alte științe de specialitate din domeniul biologic. Astfel, chimia farmaceutică se ocupă cu studiul substanțelor chimice care sunt utilizate ca <a href="/wiki/Medicament" title="Medicament">medicamente</a>, dar și al materiilor prime auxiliare utilizare în procesul de obținere a produselor farmaceutice.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> Mai exact, substanțele medicamentoase sunt studiate din punctul de vedere al identificării și sintezei, dar și posibilitatea de dezvoltare de noi entități chimice adecvate pentru utilizare terapeutică.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> </p><p>Chimia farmaceutică este o știință extrem de interdisciplinară și combină chimia organică cu biochimia, chimia computațională, farmacologia, biologia moleculară, statistica și chimia fizică. </p><p>Compușii chimici utilizați ca și substanțe medicamentoase sunt de obicei <a href="/wiki/Compus_organic" title="Compus organic">compuși organici</a>, și pot fi împărțiți în două clase: molecule organice mici (<a href="/wiki/Atorvastatin%C4%83" title="Atorvastatină">atorvastatină</a>, <a href="/w/index.php?title=Fluticazon%C4%83&amp;action=edit&amp;redlink=1" class="new" title="Fluticazonă — pagină inexistentă">fluticazonă</a>, <a href="/wiki/Clopidogrel" title="Clopidogrel">clopidogrel</a>) și produse biofarmaceutice (<a href="/wiki/Infliximab" title="Infliximab">infliximab</a>, <a href="/wiki/Eritropoietin%C4%83" title="Eritropoietină">eritropoietină</a>, <a href="/wiki/Insulin%C4%83" title="Insulină">insulină</a>). De asemenea, și <a href="/wiki/Compus_anorganic" title="Compus anorganic">compușii anorganici</a> și <a href="/wiki/Chimie_organometalic%C4%83" title="Chimie organometalică">organometalici</a> sunt folositori ca medicamente (agenți pe bază de <a href="/wiki/Litiu" title="Litiu">litiu</a> sau <a href="/wiki/Platin%C4%83" title="Platină">platină</a>, precum carbonatul de litiu și <a href="/wiki/Cisplatin" class="mw-redirect" title="Cisplatin">cisplatinul</a>). </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Descoperirea_medicamentelor">Descoperirea medicamentelor</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Chimie_farmaceutic%C4%83&amp;veaction=edit&amp;section=1" title="Modifică secțiunea: Descoperirea medicamentelor" class="mw-editsection-visualeditor"><span>modificare</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Chimie_farmaceutic%C4%83&amp;action=edit&amp;section=1" title="Edit section&#039;s source code: Descoperirea medicamentelor"><span>modificare sursă</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading2"><h2 id="Vezi_și"><span id="Vezi_.C8.99i"></span>Vezi și</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Chimie_farmaceutic%C4%83&amp;veaction=edit&amp;section=2" title="Modifică secțiunea: Vezi și" class="mw-editsection-visualeditor"><span>modificare</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Chimie_farmaceutic%C4%83&amp;action=edit&amp;section=2" title="Edit section&#039;s source code: Vezi și"><span>modificare sursă</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Farmacocinetic%C4%83" title="Farmacocinetică">Farmacocinetică</a></li> <li><a href="/wiki/Farmacognozie" title="Farmacognozie">Farmacognozie</a></li> <li><a href="/wiki/Farmacologie" title="Farmacologie">Farmacologie</a></li> <li><a href="/wiki/Farmacofor" title="Farmacofor">Farmacofor</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Referințe"><span id="Referin.C8.9Be"></span>Referințe</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Chimie_farmaceutic%C4%83&amp;veaction=edit&amp;section=3" title="Modifică secțiunea: Referințe" class="mw-editsection-visualeditor"><span>modificare</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Chimie_farmaceutic%C4%83&amp;action=edit&amp;section=3" title="Edit section&#039;s source code: Referințe"><span>modificare sursă</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><b><a href="#cite_ref-1">^</a></b> <span class="reference-text"><cite class="citation book">Zotta, Victor (<time datetime="1985">1985</time>). <i>Chimie farmaceutică</i>. București: Editura Medicală.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Chimie+farmaceutic%C4%83&amp;rft.place=Bucure%C8%99ti&amp;rft.pub=Editura+Medical%C4%83&amp;rft.date=1985&amp;rft.aulast=Zotta&amp;rft.aufirst=Victor&amp;rfr_id=info%3Asid%2Fro.wikipedia.org%3AChimie+farmaceutic%C4%83" class="Z3988"><span style="display:none;">&#160;</span></span><style data-mw-deduplicate="TemplateStyles:r16236537">.mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes:"„""”""«""»"}.mw-parser-output .citation .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-maint{display:none;color:#33aa33;margin-left:0.3em}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}</style></span> </li> <li id="cite_note-2"><b><a href="#cite_ref-2">^</a></b> <span class="reference-text"><cite class="citation book">Andrew Davis; Simon E Ward, ed. (<time datetime="2015">2015</time>). <i>Handbook of Medicinal Chemistry: Principles and Practice Editors</i>. Royal Society of Chemistry. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1039%2F9781782621836">10.1039/9781782621836</a>. <a href="/wiki/International_Standard_Book_Number" title="International Standard Book Number">ISBN</a>&#160;<a href="/wiki/Special:Referin%C8%9Be_%C3%AEn_c%C4%83r%C8%9Bi/978-1-78262-419-6" title="Special:Referințe în cărți/978-1-78262-419-6">978-1-78262-419-6</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Handbook+of+Medicinal+Chemistry%3A+Principles+and+Practice+Editors&amp;rft.pub=Royal+Society+of+Chemistry&amp;rft.date=2015&amp;rft_id=info%3Adoi%2F10.1039%2F9781782621836&amp;rft.isbn=978-1-78262-419-6&amp;rfr_id=info%3Asid%2Fro.wikipedia.org%3AChimie+farmaceutic%C4%83" class="Z3988"><span style="display:none;">&#160;</span></span><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r16236537"></span> </li> <li id="cite_note-3"><b><a href="#cite_ref-3">^</a></b> <span class="reference-text"><cite class="citation book">Roland Barret (<time datetime="2018">2018</time>). <i>Medicinal Chemistry: Fundamentals</i>. London: Elsevier. <a href="/wiki/International_Standard_Book_Number" title="International Standard Book Number">ISBN</a>&#160;<a href="/wiki/Special:Referin%C8%9Be_%C3%AEn_c%C4%83r%C8%9Bi/978-1-78548-288-5" title="Special:Referințe în cărți/978-1-78548-288-5">978-1-78548-288-5</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=book&amp;rft.btitle=Medicinal+Chemistry%3A+Fundamentals&amp;rft.place=London&amp;rft.pub=Elsevier&amp;rft.date=2018&amp;rft.isbn=978-1-78548-288-5&amp;rft.au=Roland+Barret&amp;rfr_id=info%3Asid%2Fro.wikipedia.org%3AChimie+farmaceutic%C4%83" class="Z3988"><span style="display:none;">&#160;</span></span><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r16236537"></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Legături_externe"><span id="Leg.C4.83turi_externe"></span>Legături externe</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Chimie_farmaceutic%C4%83&amp;veaction=edit&amp;section=4" title="Modifică secțiunea: Legături externe" class="mw-editsection-visualeditor"><span>modificare</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Chimie_farmaceutic%C4%83&amp;action=edit&amp;section=4" title="Edit section&#039;s source code: Legături externe"><span>modificare sursă</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://www.scribd.com/document/328427393/Chimie-Farmaceutica-Ioana-Mateiu-pdf">Chimie Farmaceutica</a> - Ioana Mateiu</li></ul> <p><br /> </p> <table class="navbox" cellspacing="0" style=""> <tbody><tr> <td style="padding:2px;"> <table cellspacing="0" class="nowraplinks collapsible autocollapse" style="width:100%;background:transparent;color:inherit;;"> <tbody><tr> <th style=";" colspan="2" class="navbox-title"><div style="float:left; width:6em;text-align:left;"><div class="noprint plainlinks" style="padding:0; font-size:xx-small; color:var(--color-base, #000); white-space:nowrap; ;"><span style=";;border:none;"><a href="/wiki/Format:Ramurile_chimiei" title="Format:Ramurile chimiei"><span title="Vizualizare format" style=";;border:none;;">v</span></a>&#160;<span style="font-size:80%;">•</span>&#160;<a href="/wiki/Discu%C8%9Bie_Format:Ramurile_chimiei" title="Discuție Format:Ramurile chimiei"><span title="Discuție format" style=";;border:none;;">d</span></a>&#160;<span style="font-size:80%;">•</span>&#160;<a class="external text" href="https://ro.wikipedia.org/w/index.php?title=Format:Ramurile_chimiei&amp;action=edit"><span title="Acest format se poate modifica. Folosiți butonul de previzualizare înainte de a salva." style=";;border:none;;">m</span></a></span></div></div><span class="" style="font-size: 110%;">Ramurile <a href="/wiki/Chimie" title="Chimie">chimiei</a></span> </th></tr> <tr style="height:2px;"> <td> </td></tr> <tr> <td class="navbox-group" style=";;"><a href="/wiki/Chimie_fizic%C4%83" title="Chimie fizică">Fizice</a> </td> <td style="text-align:left;border-left:2px solid #fdfdfd;width:100%;padding:0px;;;" class="navbox-list navbox-odd"> <div style="padding:0em 0.25em"> <a href="/wiki/Chimie_coloidal%C4%83" title="Chimie coloidală">Chimie coloidală</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_cuantic%C4%83" title="Chimie cuantică">Chimie cuantică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_fizic%C4%83" title="Chimie fizică">Chimie fizică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_nuclear%C4%83" title="Chimie nucleară">Chimie nucleară</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimia_st%C4%83rii_solide" title="Chimia stării solide">Chimia stării solide</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Cinetic%C4%83_chimic%C4%83" title="Cinetică chimică">Cinetică chimică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Cristalochimie" title="Cristalochimie">Cristalochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Electrochimie" title="Electrochimie">Electrochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Femtochimie" title="Femtochimie">Femtochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Fotochimie" title="Fotochimie">Fotochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Magnetochimie" title="Magnetochimie">Magnetochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Radiochimie" title="Radiochimie">Radiochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Sonochimie" title="Sonochimie">Sonochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Spectroscopie" title="Spectroscopie">Spectroscopie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Stereochimie" title="Stereochimie">Stereochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/%C8%98tiin%C8%9Ba_suprafe%C8%9Belor" title="Știința suprafețelor">Știința suprafețelor</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Termochimie" title="Termochimie">Termochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Termodinamic%C4%83_chimic%C4%83" title="Termodinamică chimică">Termodinamică chimică</a></div> </td></tr> <tr style="height:2px"> <td> </td></tr> <tr> <td class="navbox-group" style=";;"><a href="/wiki/Chimie_organic%C4%83" title="Chimie organică">Organice</a> </td> <td style="text-align:left;border-left:2px solid #fdfdfd;width:100%;padding:0px;;;" class="navbox-list navbox-even"><div style="padding:0em 0.25em"> <a href="/wiki/Biochimie" title="Biochimie">Biochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Biogeochimie" title="Biogeochimie">Biogeochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Biologie_chimic%C4%83" title="Biologie chimică">Biologie chimică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_bioorganic%C4%83" title="Chimie bioorganică">Chimie bioorganică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_biofizic%C4%83" title="Chimie biofizică">Chimie biofizică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_clinic%C4%83" title="Chimie clinică">Chimie clinică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a class="mw-selflink selflink">Chimie farmaceutică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/w/index.php?title=Chimia_fulerenelor&amp;action=edit&amp;redlink=1" class="new" title="Chimia fulerenelor — pagină inexistentă">Chimia fulerenelor</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_medical%C4%83" class="mw-redirect" title="Chimie medicală">Chimie medicală</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_organic%C4%83" title="Chimie organică">Chimie organică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_fizic%C4%83" title="Chimie fizică">Chimie organică fizică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimia_polimerilor" title="Chimia polimerilor">Chimia polimerilor</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Farmacie" title="Farmacie">Farmacie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Fitochimie" title="Fitochimie">Fitochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Neurochimie" title="Neurochimie">Neurochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Petrochimie" title="Petrochimie">Petrochimie</a></div> </td></tr> <tr style="height:2px"> <td> </td></tr> <tr> <td class="navbox-group" style=";;"><a href="/wiki/Chimie_anorganic%C4%83" title="Chimie anorganică">Anorganice</a> </td> <td style="text-align:left;border-left:2px solid #fdfdfd;width:100%;padding:0px;;;" class="navbox-list navbox-odd"><div style="padding:0em 0.25em"> <a href="/w/index.php?title=Chimia_agregatelor&amp;action=edit&amp;redlink=1" class="new" title="Chimia agregatelor — pagină inexistentă">Chimia agregatelor</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_anorganic%C4%83" title="Chimie anorganică">Chimie anorganică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_bioanorganic%C4%83" title="Chimie bioanorganică">Chimie bioanorganică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_organometalic%C4%83" title="Chimie organometalică">Chimie organometalică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/%C8%98tiin%C8%9Ba_materialelor" title="Știința materialelor">Știința materialelor</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Geochimie" title="Geochimie">Geochimie</a></div> </td></tr> <tr style="height:2px"> <td> </td></tr> <tr> <td class="navbox-group" style=";;">Altele </td> <td style="text-align:left;border-left:2px solid #fdfdfd;width:100%;padding:0px;;;" class="navbox-list navbox-even"><div style="padding:0em 0.25em"> <a href="/wiki/Astrochimie" title="Astrochimie">Astrochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimia_actinidelor" title="Chimia actinidelor">Chimia actinidelor</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_alimentar%C4%83" title="Chimie alimentară">Chimie alimentară</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_ambiental%C4%83" title="Chimie ambientală">Chimie ambientală</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_analitic%C4%83" title="Chimie analitică">Chimie analitică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_atmosferic%C4%83" title="Chimie atmosferică">Chimie atmosferică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_computa%C8%9Bional%C4%83" title="Chimie computațională">Chimie computațională</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_ecologic%C4%83" class="mw-redirect" title="Chimie ecologică">Chimie ecologică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_general%C4%83" title="Chimie generală">Chimie generală</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_supramolecular%C4%83" title="Chimie supramoleculară">Chimie supramoleculară</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_teoretic%C4%83" title="Chimie teoretică">Chimie teoretică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chimie_verde" title="Chimie verde">Chimie verde</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chemoinformatic%C4%83" title="Chemoinformatică">Chemoinformatică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Chemometrie" title="Chemometrie">Chemometrie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Cosmochimie" title="Cosmochimie">Cosmochimie</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; <a href="/wiki/Educa%C8%9Bie_chimic%C4%83" title="Educație chimică">Educație chimică</a> &#160;<span style="font-weight:bold;">&#183;</span>&#32; 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