New UCSF Study to Find out What Drives Cancer in Asian Americans

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id="block-ucsf-content" class="block block-system block-system-main-block"> <main class="main "> <a id="main-content" tabindex="-1"></a> <figure data-history-node-id="427586" class="article-medium-banner"> <figure> <picture class="field field-banner-image field--type-entity-reference field--label-hidden field__item"> <source srcset="/sites/default/files/styles/article_feature_banner__image/public/2024-05/scarlett-gomez-looking-at-data.jpg 1x, /sites/default/files/styles/feature_banner_2x/public/2024-05/scarlett-gomez-looking-at-data.jpg 2x" media="all and (min-width: 1280px)" type="image/jpeg" width="1440" height="780"/> <source srcset="/sites/default/files/styles/feature_banner_large/public/2024-05/scarlett-gomez-looking-at-data.jpg 1x, /sites/default/files/styles/feature_banner_2x/public/2024-05/scarlett-gomez-looking-at-data.jpg 2x" media="all and (min-width: 1050px) and (max-width: 1280px)" type="image/jpeg" width="1280" height="693"/> <source srcset="/sites/default/files/styles/feature_banner_medium/public/2024-05/scarlett-gomez-looking-at-data.jpg 1x, /sites/default/files/styles/feature_banner_medium_2x/public/2024-05/scarlett-gomez-looking-at-data.jpg 2x" media="all and (min-width: 850px) and (max-width: 1049px)" type="image/jpeg" width="1050" height="569"/> <source srcset="/sites/default/files/styles/feature_banner_narrow/public/2024-05/scarlett-gomez-looking-at-data.jpg 1x, /sites/default/files/styles/feature_banner_narrow_2x/public/2024-05/scarlett-gomez-looking-at-data.jpg 2x" media="all and (min-width: 769px) and (max-width: 849px)" type="image/jpeg" width="850" height="460"/> <source srcset="/sites/default/files/styles/feature_banner_small/public/2024-05/scarlett-gomez-looking-at-data.jpg 1x, /sites/default/files/styles/feature_banner_small_2x/public/2024-05/scarlett-gomez-looking-at-data.jpg 2x" media="all and (max-width: 768px)" type="image/jpeg" width="769" height="417"/> <source srcset="/sites/default/files/styles/featur_banner_x_small/public/2024-05/scarlett-gomez-looking-at-data.jpg 1x, /sites/default/files/styles/featur_banner_x_small_2x/public/2024-05/scarlett-gomez-looking-at-data.jpg 2x" media="all and (max-width: 599px)" type="image/jpeg" width="600" height="325"/> <img loading="eager" src="/sites/default/files/styles/article_feature_banner__image/public/2024-05/scarlett-gomez-looking-at-data.jpg" width="1440" height="780" alt="Scarlett Gomez and Debby Oh examine a screen with a map of the California Bay Area that displays cancer data. The room is dark, and in the foreground is a laptop, of which the screen reflects the researchers and the projection screen." class="element-fade"/> </picture> </figure> </figure> <div class="main-content narrow-page"> <header class="article-header article-medium-header"> <ul class="article-header__byline"> <li class="article-header__primary-area" data-primary-area="pa-research">Research</li> <li class="article-header__date"> <div class="field field-date-and-time field--type-datetime field--label-hidden field__item"><time datetime="2024-05-21T16:29:34Z" class="datetime"> May 21, 2024 </time> </div> </li> </ul> <h1><span class="field field--name-title field--type-string field--label-hidden">New UCSF Study to Find out What Drives Cancer in Asian Americans</span> </h1> <h2 class="field field-sub-title field--type-text field--label-hidden article-header__subheading">National Cancer Institute awards $12.45 million to lead the first long-term cancer study of diverse U.S. Asian ethnic groups.</h2> <p class="article-header__author"> By <a href="https://www.ucsf.edu/bio/victoria-colliver">Victoria Colliver</a> <span class="article-art-credit">Scarlett Gomez, PhD, MPH (left), examines Bay Area cancer rates. Photo by Noah Berger</span> </p> </header> <ul class="article-meta-share"> <li><a rel="nofollow" href="https://www.facebook.com/share.php?u=https://www.ucsf.edu/news/2024/05/427586/new-ucsf-study-find-out-what-drives-cancer-asian-americans" target="_blank" title="Share on Facebook"><span class="fab fa-facebook-square"></span> <span class="indent-text">Share on Facebook</span></a></li> <li><a rel="nofollow" href="https://www.twitter.com/share?text=New UCSF Study to Find out What Drives Cancer in Asian Americans&url=https://www.ucsf.edu/news/2024/05/427586/new-ucsf-study-find-out-what-drives-cancer-asian-americans" target="_blank" title="Share on Twitter"><span class="fa-brands fa-square-x-twitter"></span> <span class="indent-text">Share on Twitter</span></a></li> <li><a rel="nofollow" href="https://www.reddit.com/submit?url=https://www.ucsf.edu/news/2024/05/427586/new-ucsf-study-find-out-what-drives-cancer-asian-americans&title=New UCSF Study to Find out What Drives Cancer in Asian Americans" target="_blank" title="Share on Reddit"><span class="fab fa-reddit-square"></span> <span class="indent-text">Share on Reddit</span></a></li> <li><a rel="nofollow" href="/cdn-cgi/l/email-protection#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" title="Email this article"><span class="fas fa-envelope-square"></span> <span class="indent-text">Email this article</span></a></li> <li><a rel="nofollow" onclick="window.print();return false;" href="https://www.ucsf.edu/news/2024/05/427586/new-ucsf-study-find-out-what-drives-cancer-asian-americans" title="Print this article"><span class="fas fa-print"></span> <span class="indent-text">Print this article</span></a></li> </ul> <div class="page_narrow"><p>UC San Francisco researchers have received $12.45 million from the National Cancer Institute (NCI) to lead the first long-term study of cancer among Asian Americans, a highly diverse yet understudied group.</p> <p>Despite a growing incidence of cancers that in some cases exceed those of other groups, there has never been a national longitudinal study of cancer in the Asian American community, and there are many open questions.</p> <blockquote class="blockquote blockquote--full-right blockquote--color-violet"> <p class="blockquote-content__text">The fact there’s been so little funded research in the cancer etiology of Asian Americans continues to perpetuate the sense that the cancer burden in these populations is very low.”</p> <footer> <p class="blockquote-content__cite">Scarlett Lin Gomez, PhD, MPH</p> </footer> </blockquote> <p>For example, the researchers are seeking to understand why Asian American women who never smoked are susceptible to lung cancer, and why Asian Americans have become the first racial/ethnic group for whom cancer is the leading cause of death.</p> <p>Researchers also plan to study the increasing rates of breast cancer, especially among young Asian American women; and the relatively high rates of nasopharyngeal cancer, a type of head-and-neck cancer, in Chinese Americans; as well as liver cancer in Southeast Asian Americans; gastric cancer in Korean and Japanese Americans; and thyroid cancer in Filipino Americans.</p> <p>Asian Americans are the fastest growing racial and ethnic group in the United States and comprise 7% of the population. Yet, as of 2020, less than 1% of funding from the National Institutes of Health was devoted to research on Asian Americans. A 2016 review of NCI grants found almost no studies on the causes of cancer among Asian Americans.</p> <p>“The fact there’s been so little funded research in the cancer etiology of Asian Americans continues to perpetuate the sense that the cancer burden in these populations is very low,” said <a href="https://profiles.ucsf.edu/scarlett.gomez">Scarlett Lin Gomez</a>, PhD, MPH, co-leader of the Cancer Control Program at the Helen Diller Family Comprehensive Cancer Center, a professor of epidemiology and biostatistics, and one of three co-principal investigators of the study. “That the NCI recognized this as a major gap and will be providing funding for this historic cohort is a significant step forward.”</p> <div style="background-color:#f2f4f6; padding-left:7%; padding-right:7%; padding-top:5%; padding-bottom:3%;"> <p class="null">Iona Cheng, PhD, MPH; Scarlett Lin Gomez, PhD, MPH; and Salma Shariff Marco, PhD, MPH, are the three co-principal investigators of the first long-term study of cancer among Asian Americans.</p> <dom-threecolumn-layout data-column1-color="transparent" data-column1-size="33" data-column2-color="transparent" data-column2-size="33" data-column3-color="transparent" data-column3-size="33"> <div class="column1" slot="column1" style="--column1-color: var(--bg-transparent); --column1-size: var(--size-33); --column1-font-color: var(--font-black)"> <figure class="caption caption-drupal-entity"> <figure data-embed-button="media_assets" data-entity-embed-display="entity_reference:media_thumbnail" data-entity-embed-display-settings="{"image_style":"","image_link":"","image_loading":{"attribute":"lazy"},"link_title":"","link_url":"","target":0}" data-entity-type="media" data-entity-uuid="d9f9444c-9dd1-4854-8438-2f815f6f941b" data-langcode="en" class="embedded-entity"><picture> <img loading="lazy" src="/sites/default/files/2024-05/Iona-Cheng.jpg" width="800" height="800" alt="Headshot of Iona Cheng." class="element-fade"> </picture></figure> <figcaption><strong>Iona Cheng, PhD, MPH</strong></figcaption> </figure> </div> <div class="column2" slot="column2" style="--column2-color: var(--bg-transparent); --column2-size: var(--size-33); --column2-font-color: var(--font-black)"> <figure class="caption caption-drupal-entity"> <figure data-embed-button="media_assets" data-entity-embed-display="entity_reference:media_thumbnail" data-entity-embed-display-settings="{"image_style":"","image_link":"","image_loading":{"attribute":"lazy"},"link_title":"","link_url":"","target":0}" data-entity-type="media" data-entity-uuid="0a7f1c13-e70f-4cb8-9c1a-289f3c6122fb" data-langcode="en" class="embedded-entity"><picture> <img loading="lazy" src="/sites/default/files/2024-05/Scarlett-Gomez.jpg" width="800" height="800" alt="Headshot of Scarlett Gomez." class="element-fade"> </picture></figure> <figcaption><strong>Scarlett Lin Gomez, PhD, MPH</strong></figcaption> </figure> </div> <div class="column3" slot="column3" style="--column3-color: var(--bg-transparent); --column3-size: var(--size-33); --column3-font-color: var(--font-black)"> <figure class="caption caption-drupal-entity"> <figure data-embed-button="media_assets" data-entity-embed-display="entity_reference:media_thumbnail" data-entity-embed-display-settings="{"image_style":"","image_link":"","image_loading":{"attribute":"lazy"},"link_title":"","link_url":"","target":0}" data-entity-type="media" data-entity-uuid="08bf6448-b87d-4e06-82e0-e1e1558e9026" data-langcode="en" class="embedded-entity"><picture> <img loading="lazy" src="/sites/default/files/2024-05/salma-shariff.jpg" width="800" height="800" alt="Headshot of Salma Shariff-Marco." class="element-fade"> </picture></figure> <figcaption><strong>Salma Shariff-Marco, PhD, MPH</strong></figcaption> </figure> </div> </dom-threecolumn-layout> <p class="small-text"><em>Photos by Marco Sanchez</em></p> </div> <p> </p> <h2>Study seeks participants from every Asian American group</h2> <p>The grant supports the creation of a national cohort called ASPIRE, or ASian American ProspectIve REseach. Gomez, along with co-principal investigators <a href="https://profiles.ucsf.edu/iona.cheng">Iona Cheng</a>, PhD, MPH, and <a href="https://profiles.ucsf.edu/salma.shariff-marco">Salma Shariff-Marco</a>, PhD, MPH, will lead the effort in collaboration with UC Davis, UC Irvine, UC Los Angeles, Cedars-Sinai, the University of Hawaii, Temple University, and Jefferson University.</p> <p>"As the first national cohort to study cancer risks in our diverse Asian American communities, this is a historic milestone,” said former U.S. Assistant Secretary for Health, Howard Koh, MD, MPH, of the Harvard T. H. Chan School of Public Health and the Harvard Kennedy School, who serves on ASPIRE’s scientific advisory board. “Our communities have been waiting for this moment for a lifetime, and we hope they will join the call to action to be a part of ASPIRE."</p> <p>The initial cohort will be supported by a national network of partners across about 20 academic institutions, 40 community organizations, and two policy groups committed to Asian American health. In the coming years, they plan to recruit 20,000 men and women between the ages of 40 and 75 years old from all Asian American ethnic groups with diverse socioeconomic levels and lifestyles. They aim to expand the study to at least 50,000 participants.</p> <p>Recruitment will be centered in selected regions that comprise more than a third of the Asian American population: California (the Bay Area, L.A, Orange County, and Sacramento) as well as the New York metropolitan region, including North Jersey, and the Philadelphia metropolitan area, which includes South Jersey. Researchers also will recruit nationally.</p> <h2>Alarming trends that need continued study</h2> <p>Cancer patterns for Asian Americans differ from those found in Asian countries, and new research shows anti-Asian discrimination has increased such cancer health risks as tobacco use and obesity. It also affects the extent to which Asian Americans get screened for cancer and utilize other types of health care.</p> <p>“There are unique cancer burdens in these groups, and the patterns and trends get lost when Asian American data are aggregated into one single statistic,” said Cheng, a professor of epidemiology and biostatistics. “We don’t have cohort studies that can tell us what the risk factors are for cancer in diverse Asian American populations.”</p> </div> <div class="tags-menu-region"> <h3 class="tags-menu__title">Topics</h3> <ul class="tags-menu"> <li class="tags-menu__item"><a href="/topics/cancer" hreflang="en">Cancer</a></li> <li class="tags-menu__item"><a href="/topics/epidemiology" hreflang="en">Epidemiology</a></li> <li class="tags-menu__item"><a href="/topics/public-health" hreflang="en">Public Health</a></li> <li class="tags-menu__item"><a href="/topics/womens-health" hreflang="en">Women’s Health</a></li> </ul> </div> </div> </main> <aside 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New UCSF Study to Find out What Drives Cancer in Asian Americans | UC San Francisco