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[{"id":54468803,"identifier":"Attachment_54468803","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":34602867,"created_at":"2017-09-18T20:49:18.160-07:00","from_world_paper_id":null,"updated_at":"2024-11-15T02:03:16.813-08:00","_data":{"grobid_abstract":"Despite the advancement in medicine, management of heart failure (HF), which usually presents as a disease syndrome, has been a challenge to healthcare providers. This is reflected by the relatively higher rate of readmissions along with increased mortality and morbidity associated with HF. In this review article, we first provide a general overview of types of HF pathogenesis and diagnostic features of HF including the crucial role of exercise in determining the severity of heart failure, the efficacy of therapeutic strategies and the morbidity/mortality of HF. We then discuss the quality control measures to prevent the growing readmission rates for HF. We also attempt to elucidate published and ongoing clinical trials for HF in an effort to evaluate the standard and novel therapeutic approaches, including stem cell and gene therapies, to reduce the morbidity and mortality. Finally, we discuss the appropriate utilization/documentation and medical coding based on the severity of the HF alone and with minor and major co-morbidities. We consider that this review provides an extensive overview of the HF in terms of disease pathophysiology, management and documentation for the general readers, as well as for the clinicians/physicians/hospitalists.","grobid_abstract_attachment_id":"54468803"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Clinical Medicine Heart Failure: Diagnosis, Management and Utilization","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [68423253]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div 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PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Clinical Medicine Heart Failure: Diagnosis, Management and Utilization</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="68423253" href="https://independent.academia.edu/SaulBarriosGonzalez"><img alt="Profile image of Saul Barrios Gonzalez" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Saul Barrios Gonzalez</a></div><div class="ds-work-card--detail"></div><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" 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data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="55255972" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/55255972/Heart_Failure_Diagnosis_Management_and_Utilization">Heart Failure: Diagnosis, Management and Utilization</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="51979595" href="https://independent.academia.edu/AjinkyaInamdar">Ajinkya Inamdar</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Clinical Medicine, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Heart Failure: Diagnosis, Management and Utilization","attachmentId":71212252,"attachmentType":"pdf","work_url":"https://www.academia.edu/55255972/Heart_Failure_Diagnosis_Management_and_Utilization","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/55255972/Heart_Failure_Diagnosis_Management_and_Utilization"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="96055274" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/96055274/Introductory_Editorial_Heart_Failure_An_Exploration_of_Recent_Advances_in_Research_and_Treatment_A_">Introductory Editorial - Heart Failure: An Exploration of Recent Advances in Research and Treatment (A)</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="41633552" href="https://independent.academia.edu/ASzema">A. Szema</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinical Medicine Insights: Cardiology, 2015</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Introductory Editorial - Heart Failure: An Exploration of Recent Advances in Research and Treatment (A)","attachmentId":98060344,"attachmentType":"pdf","work_url":"https://www.academia.edu/96055274/Introductory_Editorial_Heart_Failure_An_Exploration_of_Recent_Advances_in_Research_and_Treatment_A_","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/96055274/Introductory_Editorial_Heart_Failure_An_Exploration_of_Recent_Advances_in_Research_and_Treatment_A_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="101651366" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/101651366/Heart_Failure_A_Major_Management_Challenge_With_Encouraging_Recent_Progress">Heart Failure: A Major Management Challenge With Encouraging Recent Progress</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="212372087" href="https://independent.academia.edu/PeterMacdonald29">Peter Macdonald</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Clinical Therapeutics, 2015</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Heart Failure: A Major Management Challenge With Encouraging Recent Progress","attachmentId":102133594,"attachmentType":"pdf","work_url":"https://www.academia.edu/101651366/Heart_Failure_A_Major_Management_Challenge_With_Encouraging_Recent_Progress","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/101651366/Heart_Failure_A_Major_Management_Challenge_With_Encouraging_Recent_Progress"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="92479142" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/92479142/Heart_Failure_HF_Recent_innovations_in_clinical_therapy_and_critical_profiles_of_acute_and_chronic_forms">Heart Failure (HF): Recent innovations in clinical therapy and critical profiles of acute and chronic forms</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="994898" href="https://univpm.academia.edu/GiulioPerrotta">Giulio Perrotta</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Cardiovascular Medicine and Cardiology, 2022</p><p class="ds-related-work--abstract ds2-5-body-sm">Background and objectives: Heart failure is a pathological condition characterized by the inability of the heart to pump (cardiac output) an adequate amount of blood to meet the metabolic needs of the body or, at any rate, to be able to do so only at the expense of increased filling pressures in one or more cardiac chambers and the upstream venous circulation. The research group states here the primary objective of expanding the indications contained in the ESC 2021 with the results of the last year on the subject of treatment profiles, to facilitate a better understanding of the overall clinical picture and contribute to the next edition of the guidelines.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Heart Failure (HF): Recent innovations in clinical therapy and critical profiles of acute and chronic forms","attachmentId":95477291,"attachmentType":"pdf","work_url":"https://www.academia.edu/92479142/Heart_Failure_HF_Recent_innovations_in_clinical_therapy_and_critical_profiles_of_acute_and_chronic_forms","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/92479142/Heart_Failure_HF_Recent_innovations_in_clinical_therapy_and_critical_profiles_of_acute_and_chronic_forms"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="77569482" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/77569482/New_Insights_in_the_Diagnosis_and_Treatment_of_Heart_Failure">New Insights in the Diagnosis and Treatment of Heart Failure</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33042091" href="https://johnshopkins.academia.edu/GiulioAgnetti">Giulio Agnetti</a></div><p class="ds-related-work--metadata ds2-5-body-xs">BioMed Research International, 2015</p><p class="ds-related-work--abstract ds2-5-body-sm">Cardiovascular disease is the leading cause of mortality in the US and in westernized countries with ischemic heart disease accounting for the majority of these deaths. Paradoxically, the improvements in the medical and surgical treatments of acute coronary syndrome are leading to an increasing number of “survivors” who are then developing heart failure. Despite considerable advances in its management, the gold standard for the treatment of end-stage heart failure patients remains heart transplantation. Nevertheless, this procedure can be offered only to a small percentage of patients who could benefit from a new heart due to the limited availability of donor organs. The aim of this review is to evaluate the safety and efficacy of innovative approaches in the diagnosis and treatment of patients refractory to standard medical therapy and excluded from cardiac transplantation lists.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"New Insights in the Diagnosis and Treatment of Heart Failure","attachmentId":84855265,"attachmentType":"pdf","work_url":"https://www.academia.edu/77569482/New_Insights_in_the_Diagnosis_and_Treatment_of_Heart_Failure","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/77569482/New_Insights_in_the_Diagnosis_and_Treatment_of_Heart_Failure"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="32218411" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/32218411/Heart_failure_epidemiology_investigation_and_management">Heart failure: epidemiology, investigation and management</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="62366368" href="https://independent.academia.edu/RoyGardner">Roy Gardner</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Medicine, 2010</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link 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data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/115289230/JCS_2017_JHFS_2017_Guideline_on_Diagnosis_and_Treatment_of_Acute_and_Chronic_Heart_Failure_Digest_Version_">JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure　― Digest Version ―</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="49363542" href="https://independent.academia.edu/YoshihikoSeino">Yoshihiko Seino</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Circulation Journal, 2019</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure　― Digest Version ―","attachmentId":111739572,"attachmentType":"pdf","work_url":"https://www.academia.edu/115289230/JCS_2017_JHFS_2017_Guideline_on_Diagnosis_and_Treatment_of_Acute_and_Chronic_Heart_Failure_Digest_Version_","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/115289230/JCS_2017_JHFS_2017_Guideline_on_Diagnosis_and_Treatment_of_Acute_and_Chronic_Heart_Failure_Digest_Version_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="60908952" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/60908952/Epidemiology_and_aetiology_of_heart_failure">Epidemiology and aetiology of heart failure</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="34921972" href="https://healthsciences-ucla.academia.edu/BobackZiaeian">Boback Ziaeian</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Nature Reviews Cardiology, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Epidemiology and aetiology of heart failure","attachmentId":74147403,"attachmentType":"pdf","work_url":"https://www.academia.edu/60908952/Epidemiology_and_aetiology_of_heart_failure","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/60908952/Epidemiology_and_aetiology_of_heart_failure"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="77340083" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/77340083/Heart_Failure_Causes_Investigations_and_Updates_on_Management">Heart Failure: Causes, Investigations and Updates on Management</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="121089227" href="https://mansoura.academia.edu/omarelsaka">omar elsaka</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2021</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: HF heart failure is a serious cardiovascular disease with its increased incidence, serious illness, high mortality and rapidly increasing medical costs. HF patients are increasing worldwide and South Korea is no exception. Over the past 40 years, there have been significant improvements in the definition, diagnosis, and treatment of HF. There are ongoing efforts to improve HF risk classification using biomarkers, imaging and genetic testing. Newly developed drugs and HF devices are widely accepted in clinical practice. In addition, specific treatments for end-stage renal disease, including left ventricular defense devices and heart transplants, will soon emerge. This review summarizes recent HF management and new diagnostic and therapeutic approaches to improve outcomes in HF patients. 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