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Search results for: Dita Mayasari
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class="col-md-9 mx-auto"> <form method="get" action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Dita Mayasari"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 12</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Dita Mayasari</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Hollowfiber Poly Lactid Co-Glycolic Acid (PLGA)-Collagen Coated by Chitosan as a Candidate of Small Diameter Vascular Graft</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dita%20Mayasari">Dita Mayasari</a>, <a href="https://publications.waset.org/abstracts/search?q=Zahrina%20Mardina"> Zahrina Mardina</a>, <a href="https://publications.waset.org/abstracts/search?q=Riki%20Siswanto"> Riki Siswanto</a>, <a href="https://publications.waset.org/abstracts/search?q=Agresta%20%20Ifada"> Agresta Ifada</a>, <a href="https://publications.waset.org/abstracts/search?q=Ova%20Oktavina"> Ova Oktavina</a>, <a href="https://publications.waset.org/abstracts/search?q=Prihartini%20Widiyanti"> Prihartini Widiyanti</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Heart failure is a serious major health problem with high number of mortality per year. Bypass is one of the solutions that has often been taken. Natural vascular graft (xenograft) as the substitute in bypass is inconvenient due to ethic problems and the risk of infection transmission caused by the usage of another species transgenic vascular. Nowadays, synthetic materials have been fabricated from polymers. The aim of this research is to make a synthetic vascular graft with great physical strength, high biocompatibility, and good affordability. The method of this research was mixing PLGA and collagen by magnetic stirrer. This composite were shaped by spinneret with water as coagulant. Then it was coated by chitosan with 3 variations of weight (1 gram, 2 grams, and 3 grams) to increase hemo and cytocompatibility, proliferation, and cell attachment in order for the vascular graft candidates to be more biocompatible. Mechanical strength for each variation was 5,306 MPa (chitosan 1 gram), 3,433 MPa (chitosan 2 grams) and 3,745 MPa (chitosan 3 grams). All the tensile values were higher than human vascular tensile strength. Toxicity test showed that the living cells in all variations were more than 60% in number, thus the vascular graft is not toxic. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chitosan" title="chitosan">chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=collagen" title=" collagen"> collagen</a>, <a href="https://publications.waset.org/abstracts/search?q=PLGA" title=" PLGA"> PLGA</a>, <a href="https://publications.waset.org/abstracts/search?q=spinneret" title=" spinneret"> spinneret</a> </p> <a href="https://publications.waset.org/abstracts/3156/hollowfiber-poly-lactid-co-glycolic-acid-plga-collagen-coated-by-chitosan-as-a-candidate-of-small-diameter-vascular-graft" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3156.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">398</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> Modelling and Maping Malnutrition Toddlers in Bojonegoro Regency with Mixed Geographically Weighted Regression Approach</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Elvira%20Mustikawati%20P.H.">Elvira Mustikawati P.H.</a>, <a href="https://publications.waset.org/abstracts/search?q=Iis%20Dewi%20Ratih"> Iis Dewi Ratih</a>, <a href="https://publications.waset.org/abstracts/search?q=Dita%20Amelia"> Dita Amelia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bojonegoro has proclaimed a policy of zero malnutrition. Therefore, as an effort to solve the cases of malnutrition children in Bojonegoro, this study used the approach geographically Mixed Weighted Regression (MGWR) to determine the factors that influence the percentage of malnourished children under five in which factors can be divided into locally influential factor in each district and global factors that influence throughout the district. Based on the test of goodness of fit models, R2 and AIC values in GWR models are better than MGWR models. R2 and AIC values in MGWR models are 84.37% and 14.28, while the GWR models respectively are 91.04% and -62.04. Based on the analysis with GWR models, District Sekar, Bubulan, Gondang, and Dander is a district with three predictor variables (percentage of vitamin A, the percentage of births assisted health personnel, and the percentage of clean water) that significantly influence the percentage of malnourished children under five. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=GWR" title="GWR">GWR</a>, <a href="https://publications.waset.org/abstracts/search?q=MGWR" title=" MGWR"> MGWR</a>, <a href="https://publications.waset.org/abstracts/search?q=R2" title=" R2"> R2</a>, <a href="https://publications.waset.org/abstracts/search?q=AIC" title=" AIC"> AIC</a> </p> <a href="https://publications.waset.org/abstracts/2014/modelling-and-maping-malnutrition-toddlers-in-bojonegoro-regency-with-mixed-geographically-weighted-regression-approach" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2014.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">296</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Teacher Mental Health during Online Teaching</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Elisabeth%20Desiana%20Mayasari">Elisabeth Desiana Mayasari</a>, <a href="https://publications.waset.org/abstracts/search?q=Laurensia%20Aptik%20Evanjeli"> Laurensia Aptik Evanjeli</a>, <a href="https://publications.waset.org/abstracts/search?q=Brigitta%20Erlita%20Tri%20Anggadewi"> Brigitta Erlita Tri Anggadewi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The condition of the COVID-19 pandemic demands adaptation in various aspects of human life, including in the field of education. Teachers are expected to do distance learning or Learning From Home (LFH). The teacher said that he experienced stress, anxiety, feeling depressed, and afraid based on the interview. Learning adaptations and pandemic situations can impact the mental health of teachers, so the purpose of this study is to determine the mental health of teachers while teaching online. This research was conducted with a quantitative approach using a survey method. The subjects in this study were 330 elementary school teachers under the auspices of a foundation in Yogyakarta. Teachers' mental health was measured using the Indonesian version of The Mental Health Inventory (MHI-38), which has a reliability of 0.888. The results showed that the teachers generally had a good mental health condition marked by a lower negative aspect score than the positive aspect. In addition, the overall mental health aspect shows that some teachers have better mental health when compared to the average score, as well as higher positive aspect scores in all sub-aspects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mental%20health" title="mental health">mental health</a>, <a href="https://publications.waset.org/abstracts/search?q=teacher" title=" teacher"> teacher</a>, <a href="https://publications.waset.org/abstracts/search?q=COVID-19%20pandemic" title=" COVID-19 pandemic"> COVID-19 pandemic</a>, <a href="https://publications.waset.org/abstracts/search?q=MHI-38" title=" MHI-38"> MHI-38</a> </p> <a href="https://publications.waset.org/abstracts/143897/teacher-mental-health-during-online-teaching" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/143897.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">183</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> The Effect of Different Composition of Dairy Cattle Feces Briquette on Moisture and Briquette Density</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dita%20Aviana%20Dewi">Dita Aviana Dewi</a>, <a href="https://publications.waset.org/abstracts/search?q=Heri%20Muji"> Heri Muji</a>, <a href="https://publications.waset.org/abstracts/search?q=Dian%20Nur%20Amalia"> Dian Nur Amalia</a>, <a href="https://publications.waset.org/abstracts/search?q=Nanung%20Agus%20Fitriyanto"> Nanung Agus Fitriyanto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Utilization of cow feces as a source of alternative energy can be done with turn it as briquettes. Cow feces generate heat around 4000 Cal/g and the methane gas (CH4) are quite high. Methane gas is one of the essential elements in briquettes which serve as the ignition, so that is resulting briquettes combustible. This study aims to know the difference of the composition of the constituents of briquette moisture content and density. Dairy cattle feces used as the main ingredient with additional material from the waste of the agricultural industry in the form of husk. This study was conducted with three treatments, namely T0= feces 1: husk 1, T1= feces 2: husk 1, and T2= feces 3: husk 1. Each treatment was replicated three times. The experimental design used was Complete Random Design Pattern in line with testing of Dunnet. The observed variables are moisture content and density of the briquettes. Results of this study showed an average moisture content of T0 is 31,17%, T1 is 28,14%, and T2 is 49.95%. The average density of briquettes at T0 is 1,0787 g/cm3, T1 is 1,1448 g/cm3, and T2 is 1,1133 g/cm3. Summary of the study is to take the difference of the composition of the feces and the husk do not have significant effects on moisture content and density of briquettes (p < 0.05). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dairy%20cattle%20feces" title="dairy cattle feces">dairy cattle feces</a>, <a href="https://publications.waset.org/abstracts/search?q=briquette" title=" briquette"> briquette</a>, <a href="https://publications.waset.org/abstracts/search?q=moisture" title=" moisture"> moisture</a>, <a href="https://publications.waset.org/abstracts/search?q=density" title=" density"> density</a> </p> <a href="https://publications.waset.org/abstracts/27127/the-effect-of-different-composition-of-dairy-cattle-feces-briquette-on-moisture-and-briquette-density" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27127.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">738</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> The Implementation of Entrepreneurial Marketing in Small Business Enterprise</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Iin%20Mayasari">Iin Mayasari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study aims at exploring the influence of aspects of entrepreneurial marketing on a firm鈥檚 performance. Entrepreneurs are not only supported by resources control to obtain sustainable competitive advantage, but it should also be supported by intangible resources. Entrepreneurial marketing provides the opportunity for entrepreneurs to proactively find better ways to create value for desired customers, to create innovation, and to build customer equity. Entrepreneurial marketing has the medium between entrepreneurship and marketing, and serves as an umbrella for many of the emergent perspectives on marketing. It has eight underlying dimensions. They are proactiveness, calculated risk-taking, innovativeness, an opportunity focus, entrepreneurial orientation, resource leveraging, customer intensity, and value creating. The research method of the study was a qualitative study by having an interview with 8 small companies in Kudus Region, the Central Java, Indonesia. The interviewees were the owner and the manager of the company that had the scope work of small business enterprise in wood crafting industry. The interview was related to the implementation of the elements of the entrepreneurial marketing. The result showed that the small business enterprises had implemented the elements of entrepreneurial marketing in supporting their daily activities. The understanding based on the theoretical implementation was well executed by the owner and managers. The problems in managing small business enterprises were related to the full support by the government and the branding management. Furthermore, the innovation process should be improved especially the use of internet to promote the product, to expand the market and to increase the firm鈥檚 performance. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=entrepreneurial%20marketing" title="entrepreneurial marketing">entrepreneurial marketing</a>, <a href="https://publications.waset.org/abstracts/search?q=innovativeness" title=" innovativeness"> innovativeness</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20taking" title=" risk taking"> risk taking</a>, <a href="https://publications.waset.org/abstracts/search?q=opportunity%20focus" title=" opportunity focus"> opportunity focus</a> </p> <a href="https://publications.waset.org/abstracts/65492/the-implementation-of-entrepreneurial-marketing-in-small-business-enterprise" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/65492.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">298</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Understanding the Complexity of Corruption and Anti-Corruption in Indonesia's Mining Industry: Challenges and Opportunities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Khoirul%20Umam">Ahmad Khoirul Umam</a>, <a href="https://publications.waset.org/abstracts/search?q=Iin%20Mayasari"> Iin Mayasari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Indonesia is blessed with rich natural resources and frequently dubbed as the 6th richest country in the world in terms of mining resources, including minerals and coal. Mining can contribute to the socio-economic development by generating state revenue for development, elevating poverty through employment, opening and developing remote areas, putting in basic infrastructure and creating new centres of developments. However, favouritism and rent-seeking behaviour committed by government officials, politicians, and business players in licensing and permit giving in mining and forestry sectors have resisted reforms. Even though Indonesia鈥檚 Corruption Eradication Commission (KPK) successfully targeted untouchable actors, public criticism continues to focus on questions of why corruption apparently remains systemic in mining industry in the country? This paper revealed that structural anomalies, as well as legacies of the Soeharto era鈥檚 power inequities, have severely inhibited Indonesia鈥檚 bureaucratic arrangements that continue to influence adversely the elements of transparency and accountability in mining industry governance. In the more liberalized and decentralized political system, the deficiencies have gradually assisted vested interest groups to band together, thus creating a coalition that can challenge, resist, and contain anti-graft actions. Therefore, Indonesia needs much more serious anti-corruption actions that would require eliminating the monopoly over power, enhancing competition, limiting discretion, and clarifying the rules of business and political competition in the mining sector in the country. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anti-corruption" title="anti-corruption">anti-corruption</a>, <a href="https://publications.waset.org/abstracts/search?q=public%20integrity" title=" public integrity"> public integrity</a>, <a href="https://publications.waset.org/abstracts/search?q=private%20integrity" title=" private integrity"> private integrity</a>, <a href="https://publications.waset.org/abstracts/search?q=mining%20industry" title=" mining industry"> mining industry</a>, <a href="https://publications.waset.org/abstracts/search?q=democratization" title=" democratization"> democratization</a> </p> <a href="https://publications.waset.org/abstracts/109029/understanding-the-complexity-of-corruption-and-anti-corruption-in-indonesias-mining-industry-challenges-and-opportunities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/109029.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">111</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Evaluation of Railway Network and Service Performance Based on Transportation Sustainability in DKI Jakarta</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nur%20Bella%20Octoria%20Bella">Nur Bella Octoria Bella</a>, <a href="https://publications.waset.org/abstracts/search?q=Ayomi%20Dita%20Rarasati"> Ayomi Dita Rarasati</a> </p> <p class="card-text"><strong>Abstract:</strong></p> DKI Jakarta is Indonesia's capital city with the 10th highest congestion rate in the world based on the 2019 traffic index. Other than that based on World Air Quality Report in 2019 showed DKI Jakarta's air pollutant concentrate 49.4 碌g and the 5th highest air pollutant in the world. In the urban city nowadays, the mobility rate is high enough and the efficiency for sustainability assessment in transport infrastructure development is needed. This efficiency is the important key for sustainable infrastructure development. DKI Jakarta is nowadays in the process of constructing the railway infrastructure to support the transportation system. The problems appearing are the railway infrastructure networks and the service in DKI Jakarta already planned based on sustainability factors or not. Therefore, the aim of this research is to make the evaluation of railways infrastructure networks performance and services in DKI Jakarta regards on the railway sustainability key factors. Further, this evaluation will be used to make the railway sustainability assessment framework and to offer some of the alternative solutions to improve railway transportation sustainability in DKI Jakarta. Firstly a very detailed literature review of papers that have focused on railway sustainability factors and their improvements of railway sustainability, published in the scientific journal in the period 2011 until 2021. Regarding the sustainability factors from the literature review, further, it is used to assess the current condition of railway infrastructure in DKI Jakarta. The evaluation will be using a Likert rate questionnaire and directed to the transportation railway expert and the passenger. Furthermore, the mapping and evaluation rate based on the sustainability factors will be compared to the effect factors using the Analytical Hierarchical Process (AHP). This research offers the network's performance and service rate impact on the sustainability aspect and the passenger willingness for using the rail public transportation in DKI Jakarta. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=transportation%20sustainability" title="transportation sustainability">transportation sustainability</a>, <a href="https://publications.waset.org/abstracts/search?q=railway%20transportation" title=" railway transportation"> railway transportation</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainability" title=" sustainability"> sustainability</a>, <a href="https://publications.waset.org/abstracts/search?q=DKI%20Jakarta" title=" DKI Jakarta"> DKI Jakarta</a> </p> <a href="https://publications.waset.org/abstracts/145104/evaluation-of-railway-network-and-service-performance-based-on-transportation-sustainability-in-dki-jakarta" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/145104.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">163</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> High-Resolution Flood Hazard Mapping Using Two-Dimensional Hydrodynamic Model Anuga: Case Study of Jakarta, Indonesia </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hengki%20Eko%20Putra">Hengki Eko Putra</a>, <a href="https://publications.waset.org/abstracts/search?q=Dennish%20Ari%20Putro"> Dennish Ari Putro</a>, <a href="https://publications.waset.org/abstracts/search?q=Tri%20Wahyu%20Hadi"> Tri Wahyu Hadi</a>, <a href="https://publications.waset.org/abstracts/search?q=Edi%20Riawan"> Edi Riawan</a>, <a href="https://publications.waset.org/abstracts/search?q=Junnaedhi%20Dewa%20Gede"> Junnaedhi Dewa Gede</a>, <a href="https://publications.waset.org/abstracts/search?q=Aditia%20Rojali"> Aditia Rojali</a>, <a href="https://publications.waset.org/abstracts/search?q=Fariza%20Dian%20Prasetyo"> Fariza Dian Prasetyo</a>, <a href="https://publications.waset.org/abstracts/search?q=Yudhistira%20Satya%20Pribadi"> Yudhistira Satya Pribadi</a>, <a href="https://publications.waset.org/abstracts/search?q=Dita%20Fatria%20Andarini"> Dita Fatria Andarini</a>, <a href="https://publications.waset.org/abstracts/search?q=Mila%20Khaerunisa"> Mila Khaerunisa</a>, <a href="https://publications.waset.org/abstracts/search?q=Raditya%20Hanung%20Prakoswa"> Raditya Hanung Prakoswa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Catastrophe risk management can only be done if we are able to calculate the exposed risks. Jakarta is an important city economically, socially, and politically and in the same time exposed to severe floods. On the other hand, flood risk calculation is still very limited in the area. This study has calculated the risk of flooding for Jakarta using 2-Dimensional Model ANUGA. 2-Dimensional model ANUGA and 1-Dimensional Model HEC-RAS are used to calculate the risk of flooding from 13 major rivers in Jakarta. ANUGA can simulate physical and dynamical processes between the streamflow against river geometry and land cover to produce a 1-meter resolution inundation map. The value of streamflow as an input for the model obtained from hydrological analysis on rainfall data using hydrologic model HEC-HMS. The probabilistic streamflow derived from probabilistic rainfall using statistical distribution Log-Pearson III, Normal and Gumbel, through compatibility test using Chi Square and Smirnov-Kolmogorov. Flood event on 2007 is used as a comparison to evaluate the accuracy of model output. Property damage estimations were calculated based on flood depth for 1, 5, 10, 25, 50, and 100 years return period against housing value data from the BPS-Statistics Indonesia, Centre for Research and Development of Housing and Settlements, Ministry of Public Work Indonesia. The vulnerability factor was derived from flood insurance claim. Jakarta's flood loss estimation for the return period of 1, 5, 10, 25, 50, and 100 years, respectively are Rp 1.30 t; Rp 16.18 t; Rp 16.85 t; Rp 21.21 t; Rp 24.32 t; and Rp 24.67 t of the total value of building Rp 434.43 t. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=2D%20hydrodynamic%20model" title="2D hydrodynamic model">2D hydrodynamic model</a>, <a href="https://publications.waset.org/abstracts/search?q=ANUGA" title=" ANUGA"> ANUGA</a>, <a href="https://publications.waset.org/abstracts/search?q=flood" title=" flood"> flood</a>, <a href="https://publications.waset.org/abstracts/search?q=flood%20modeling" title=" flood modeling"> flood modeling</a> </p> <a href="https://publications.waset.org/abstracts/58115/high-resolution-flood-hazard-mapping-using-two-dimensional-hydrodynamic-model-anuga-case-study-of-jakarta-indonesia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58115.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">275</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Nanoemulsion Formulation of Ethanolic Extracts of Propolis and Its Antioxidant Activity</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rachmat%20Mauludin">Rachmat Mauludin</a>, <a href="https://publications.waset.org/abstracts/search?q=Dita%20Sasri%20Primaviri"> Dita Sasri Primaviri</a>, <a href="https://publications.waset.org/abstracts/search?q=Irda%20Fidrianny"> Irda Fidrianny</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Propolis contains several antioxidant compounds which can be used in topical application to protect skin against free radical, prevent skin cancer and skin aging. Previous study showed that 70% ethanolic extract of propolis (EEP) provided the greatest antioxidant activity. Since EEP has very small solubility in water, the extract was prepared in nanoemulsion (NE). Nanoemulsion is chosen as cosmetic dosage forms according to its properties namely to decrease the risk of skin鈥檚 irritation, increase penetration, prolong its time to remain in our skin, and improve stability. Propolis was extracted using reflux methods and concentrated using rotavapor. EEP was characterized with several tests such as phytochemical screening, density, and antioxidant activity using DPPH method. Optimation of total surfactant, co-surfactant, oil, and amount of EEP that can be included in NE were required to get the best NE formulation. The evaluations included to organoleptic observation, globul size, polydispersity index, morphology using TEM, viscosity, pH, centrifuge, stability, Freeze and Thaw test, radical scavenging activity using DPPH method, and primary irritation test. The yield extracts was 11.12% from raw propolis contained of steroid/triterpenoid, flavonoid, and saponin based on phytochemical screening. EEP had the value of DPPH scavenging activity 61.14% and IC50 0.41629 ppm. The best NE formulation consisted of 26.25% Kolliphor RH40; 8.75% glycerine; 5% rice bran oil; and 3% EEP. NE was transparant, had globul size of 21.9 nm; polydispersity index of 0.338; and pH of 5.67. Based on TEM morphology, NE was almost spherical and has particle size below 50 nm. NE propolis revealed to be physically stable after stability test within 63 days at 25oC, centrifuged for 30 mins at 13.000 rpm, and passed 6 cycles of Freeze and Thaw test without separated. NE propolis reduced 58% of free radical DPPH similar to antioxidant activity of the original extracts. Antioxidant activity of NE propolis is relatively stable after stored for 6 weeks. NE Propolis was proven to be safe by primary irritation test with the value of primary irritation index (OECD) was 0. The best formulation for NE propolis contained of 26.25% Kolliphor RH40; 8.75% glycerine; 5% rice bran oil; and 3% EEP with globul size of 21.9 nm and polydispersity index of 0.338. NE propolis was stable and had antioxidant activity similar to EEP. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=propolis" title="propolis">propolis</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoemulsion" title=" nanoemulsion"> nanoemulsion</a>, <a href="https://publications.waset.org/abstracts/search?q=irritation%20test" title=" irritation test"> irritation test</a> </p> <a href="https://publications.waset.org/abstracts/20332/nanoemulsion-formulation-of-ethanolic-extracts-of-propolis-and-its-antioxidant-activity" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/20332.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">305</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Propolis as Antioxidant Formulated in Nanoemulsion</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rachmat%20Mauludin">Rachmat Mauludin</a>, <a href="https://publications.waset.org/abstracts/search?q=Irda%20Fidrianny"> Irda Fidrianny</a>, <a href="https://publications.waset.org/abstracts/search?q=Dita%20Sasri%20Primaviri"> Dita Sasri Primaviri</a>, <a href="https://publications.waset.org/abstracts/search?q=Okti%20Alifiana"> Okti Alifiana</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Natural products such as propolis, green tea and corncob are containing several compounds called antioxidant. Antioxidant can be used in topical application to protect skin against free radical, prevent skin cancer and skin aging. Previous study showed that the extract of propolis that has the highest antioxidant activity was ethanolic extract of propolis (EEP). It is important to make a dosage form that could keep the stability and could protect the effectiveness of antioxidant activity of the extracts. In this research, nanoemulsion (NE) was chosen to formulate those natural products. NE is a dispersion system between oil phase and water phase that formed by mechanical force with a lot amount of surfactants and has globule size below 100 nm. In pharmaceutical industries, NE was preferable for its stability, biodegradability, biocompatibility, its ease to be absorbed and eliminated, and for its use as carrier for lipophilic drugs. First, all of the natural products were extracted using reflux methods. Green tea and corncob were extracted using 96% ethanol while propolis using 70% ethanol. Then, the extracts were concentrated using rotavapor to obtain viscous extracts. The yield of EEP was 11.12%; green tea extract (GTE) was 23.37%; and corncob extract (CCE) was 17.23%. EEP contained steroid/triterpenoid, flavonoid and saponin. GTE contained flavonoid, tannin, and quinone while CCE contained flavonoid, phenol and tannin. The antioxidant activities of the extracts were then measured using DPPH scavenging capacity methods. The values of DPPH scavenging capacity were 61.14% for EEP; 97.16% for GTE; and 78.28% for CCE. The value of IC50 for EEP was 0.41629 ppm. After the extracts were evaluated, NE was prepared. Several surfactants and co-surfactants were used in many combinations and ratios in order to form a NE. Tween 80 and Kolliphor RH40 were used as surfactants while glycerin and propylene glycol were used as co-surfactants. The best NE consists of 26.25% of Kolliphor RH40; 8.75% of glycerin; 5% of rice bran oil; 3% of extracts; and 57% of water. EEP NE had globule size around 23.72 nm; polydispersity index below 0.5; and did not cause any irritation on rabbits. EEP NE was proven to be stable after passing stability test within 63 days at room temperature and 6 cycles of Freeze and Thaw test without separated. Based on TEM (Transmission Electron Microscopy) test, EEP NE had spherical structure with most of its size below 50 nm. The antioxidant activity of EEP NE was monitored for 6 weeks and showed no significant difference. The value of DPPH scavenging capacity for EEP NE was around 58%; for GTE NE was 96.75%; and for CCE NE was 55.69%. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=propolis" title="propolis">propolis</a>, <a href="https://publications.waset.org/abstracts/search?q=green%20tea" title=" green tea"> green tea</a>, <a href="https://publications.waset.org/abstracts/search?q=corncob" title=" corncob"> corncob</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoemulsion" title=" nanoemulsion"> nanoemulsion</a> </p> <a href="https://publications.waset.org/abstracts/19818/propolis-as-antioxidant-formulated-in-nanoemulsion" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19818.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">321</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Phage Capsid for Efficient Delivery of Cytotoxic Drugs</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Simona%20Dostalova">Simona Dostalova</a>, <a href="https://publications.waset.org/abstracts/search?q=Dita%20Munzova"> Dita Munzova</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20Maria%20Jimenez%20Jimenez"> Ana Maria Jimenez Jimenez</a>, <a href="https://publications.waset.org/abstracts/search?q=Marketa%20Vaculovicova"> Marketa Vaculovicova</a>, <a href="https://publications.waset.org/abstracts/search?q=Vojtech%20Adam"> Vojtech Adam</a>, <a href="https://publications.waset.org/abstracts/search?q=Rene%20Kizek"> Rene Kizek</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The boom of nanomedicine in recent years has led to the development of numerous new nanomaterials that can be used as nanocarriers in the drug delivery. These nanocarriers can either be synthetic or natural-based. The disadvantage of many synthetic nanocarriers is their toxicity in patient鈥檚 body. Protein cages that can naturally be found in human body do not exhibit such disadvantage. However, the release of cargo from some protein cages in target cells can be problematic. As a special type of protein cages can serve the capsid of many viruses, including phage. Phages infect bacterial cells; therefore they are not harmful to human cells. The targeting of phage particles to cancer cells can be solved by producing of empty phage capsids during which the targeting moieties (e.g. peptides) can be cloned into genes of phage capsid to decorate its surface. Moreover, the produced capsids do not contain viral nucleic acid and are therefore not infectious to beneficial bacteria in the patient鈥檚 body. The protein cage composed of viral capsid is larger than other frequently used apoferritin cage but its size is still small enough to benefit from passive targeting by Enhanced Permeability and Retention effect. In this work, bacteriophage 位 was used, both whole and its empty capsid for delivery of different cytotoxic drugs (cisplatin, carboplatin, oxaliplatin, etoposide and doxorubicin). Large quantities of phage 位 were obtained from phage 位-producing strain of E. coli cultivated in medium with 0.2 % maltose. After killing of E. coli with chloroform and its removal by centrifugation, the phage was concentrated by ultracentrifugation at 130 000 g and 4 掳C for 3 h. The encapsulation of the drugs was performed by infusion method and four different concentrations of the drugs were encapsulated (200; 100; 50; 25 碌g/ml). Free molecules of drugs were removed by dialysis. The encapsulation was verified using spectrophotometric and electrochemical methods. The amount of encapsulated drug linearly increased with the amount of applied drug (determination coefficient R2=0.8013). 76% of applied drug was encapsulated in phage 位 particles (concentration of 10 碌g/ml), even with the highest applied concentration of drugs, 200 碌g/ml. Only 1% of encapsulated drug was detected in phage DNA. Similar results were obtained with encapsulation in phage empty capsid. Therefore, it can be concluded that the encapsulation of drugs into phage particles is efficient and mostly occurs by interaction of drugs with protein capsid. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cytostatics" title="cytostatics">cytostatics</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20delivery" title=" drug delivery"> drug delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=nanocarriers" title=" nanocarriers"> nanocarriers</a>, <a href="https://publications.waset.org/abstracts/search?q=phage%20capsid" title=" phage capsid"> phage capsid</a> </p> <a href="https://publications.waset.org/abstracts/24931/phage-capsid-for-efficient-delivery-of-cytotoxic-drugs" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24931.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">493</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Metabolomics Fingerprinting Analysis of Melastoma malabathricum L. Leaf of Geographical Variation Using HPLC-DAD Combined with Chemometric Tools</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dian%20Mayasari">Dian Mayasari</a>, <a href="https://publications.waset.org/abstracts/search?q=Yosi%20Bayu%20Murti"> Yosi Bayu Murti</a>, <a href="https://publications.waset.org/abstracts/search?q=Sylvia%20Utami%20Tunjung%20Pratiwi"> Sylvia Utami Tunjung Pratiwi</a>, <a href="https://publications.waset.org/abstracts/search?q=Sudarsono"> Sudarsono</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Melastoma malabathricum L. is an Indo-Pacific herb that has been traditionally used to treat several ailments such as wounds, dysentery, diarrhea, toothache, and diabetes. This plant is common across tropical Indo-Pacific archipelagos and is tolerant of a range of soils, from low-lying areas subject to saltwater inundation to the salt-free conditions of mountain slopes. How the soil and environmental variation influences secondary metabolite production in the herb, and an understanding of the plant鈥檚 utility as traditional medicine, remain largely unknown and unexplored. The objective of this study is to evaluate the variability of the metabolic profiles of M. malabathricum L. across its geographic distribution. By employing high-performance liquid chromatography-diode array detector (HPLC-DAD), a highly established, simple, sensitive, and reliable method was employed for establishing the chemical fingerprints of 72 samples of M. malabathricum L. leaves from various geographical locations in Indonesia. Specimens collected from six terrestrial and archipelago regions of Indonesia were analyzed by HPLC to generate chromatogram peak profiles that could be compared across each region. Data corresponding to the common peak areas of HPLC chromatographic fingerprint were analyzed by hierarchical component analysis (HCA) and principal component analysis (PCA) to extract information on the most significant variables contributing to characterization and classification of analyzed samples data. Principal component values were identified as PC1 and PC2 with 41.14% and 19.32%, respectively. Based on variety and origin, the high-performance liquid chromatography method validated the chemical fingerprint results used to screen the in vitro antioxidant activity of M. malabathricum L. The result shows that the developed method has potential values for the quality of similar M. malabathrium L. samples. These findings provide a pathway for the development and utilization of references for the identification of M. malabathricum L. Our results indicate the importance of considering geographic distribution during field-collection efforts as they demonstrate regional metabolic variation in secondary metabolites of M. malabathricum L., as illustrated by HPLC chromatogram peaks and their antioxidant activities. The results also confirm the utility of this simple approach to a rapid evaluation of metabolic variation between plants and their potential ethnobotanical properties, potentially due to the environments from whence they were collected. This information will facilitate the optimization of growth conditions to suit particular medicinal qualities. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fingerprint" title="fingerprint">fingerprint</a>, <a href="https://publications.waset.org/abstracts/search?q=high%20performance%20liquid%20chromatography" title=" high performance liquid chromatography"> high performance liquid chromatography</a>, <a href="https://publications.waset.org/abstracts/search?q=Melastoma%20malabathricum%20l." title=" Melastoma malabathricum l."> Melastoma malabathricum l.</a>, <a href="https://publications.waset.org/abstracts/search?q=metabolic%20profiles" title=" metabolic profiles"> metabolic profiles</a>, <a href="https://publications.waset.org/abstracts/search?q=principal%20component%20analysis" title=" principal component analysis "> principal component analysis </a> </p> <a href="https://publications.waset.org/abstracts/133098/metabolomics-fingerprinting-analysis-of-melastoma-malabathricum-l-leaf-of-geographical-variation-using-hplc-dad-combined-with-chemometric-tools" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/133098.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">162</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates 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